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In this new episode, Crawlspace Media's Tim Pilleri and Lance Reenstierna discuss the mysterious death of Austria's Christian Pilnacek in October of 2023 with Dr.'s Sarah Schiffecker and David Perlmutter from Texas Tech University. Christian Pilnacek was a prominent Austrian lawyer and former judge who rose to become one of the most powerful officials in the country's Ministry of Justice before being suspended amid controversy. While his October 2023 death in a Danube tributary was quickly ruled a suicide, the circumstances remain surrounded by mystery due to allegations of a sloppy investigation and suspected political interference. Check out Dr. Schiffecker's work: https://www.depts.ttu.edu/comc/faculty/faculty/sschiffecker.php. Check out Dr. Perlmutter's work: https://www.depts.ttu.edu/comc/faculty/faculty/dperlmutter.php. Check out Quince: https://quince.com/MISSING. Check out Mint Mobile: mintmobile.com/missing. Check out Kensington Publishing: https://www.kensingtonbooks.com. Main podcast theme by Kevin Macleod. Check out his work at https://incompetech.com/. Additional music by David Williams. See his work at http://williamsflutes.com. Follow Missing: IG: https://www.instagram.com/MissingCSM/. Youtube: https://www.youtube.com/missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Neurologist and bestselling author Dr. David Perlmutter returns to discuss the groundbreaking science behind his new book, Brain Defenders. Together, we unpack why Alzheimer's disease may be driven less by amyloid plaques and more by chronic inflammation, metabolic dysfunction, and changes in the brain's immune cells. Dr. Perlmutter explains the critical role of microglia, how blood sugar and insulin resistance affect the brain, why gut health is directly connected to cognitive function, and what lifestyle habits have the strongest evidence for protecting memory as we age. → Leave Us A Voice Message! Topics Discussed: → What causes Alzheimer's disease? → How do you prevent Alzheimer'? → What foods improve brain health? → Can inflammation cause dementia? → Does blood sugar affect memory? Sponsored By: → Function | Check your health the way I do. Function provides 160+ lab tests for $1/day and member pricing on advanced imaging. Join at https://functionhealth.com/bewellbykelly and use code BEWELL25 for a $25 credit. → Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com. → Shop minnow's new apré-ski capsule collection at https://shopminnow.com and enter code MEETMINNOW15 at checkout to receive 15% off your first order. → LMNT | Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at https://drinklmnt.com/Kelly. Find your favorite LMNT flavor, or share with a friend. → Branch Basics | Go to https://branchbasics.com/BEWELLPODCAST and use code: BEWELLPODCASTfor 15% off your first purchase. Timestamps: → 00:00:00 - Introduction → 00:03:07 - Why Alzheimer's Research Is Changing → 00:05:42 - Microglia Explained → 00:10:44 - Understanding Immunomatabolism → 00:15:10 - Insulin Resistance + "Type 3 Diabetes" → 00:19:27 - Long COVID + Brain Recovery → 00:30:20 - Lifestyle Changes For Brain Health → 00:35:22 - The Gut Microbiome → 00:37:27 - Tracking Gut Health → 00:39:26 - Early Biomarkers/Testing → 00:45:20 - Exercise + Muscle → 00:49:51 - Children's Nutrition → 00:52:48 - Women's Dementia Risk → 00:58:53 - GLP1s + Other Peptides → 01:07:41 - Dr. Perlmutter's Daily Brain Health Routine Further Listening: → Nutrition for a Healthy Brain & Body (Without Counting Calories) | Max Lugavere Check Out David: → Book | Braindefenders.com → Website → Instagram Check Out Kelly: → Instagram → Youtube → Facebook
Neurologist Dr. David Perlmutter Explains Brain Inflammation and Alzheimer's Risk Your brain has its own immune system, and when it turns against you, it becomes the hidden driver behind Alzheimer's, Parkinson's, depression, and even long COVID. This episode hands you the science to recognize it early and reverse it. Get Dr. Perlmutter's new book Brain Defenders: https://drperlmutter.com/books/brain-defenders/ Host Dave Asprey sits down with Dr. David Perlmutter, a board-certified neurologist and six-time New York Times bestselling author whose work sits at the intersection of neurology, nutrition, and brain health. He is a Fellow of the American College of Nutrition, serves on its Board of Directors, and sits on the Editorial Board of the Journal of Alzheimer's Disease. His books, including the number one bestseller Grain Brain, span 32 languages and have sold over a million copies, and his upcoming release, Brain Defenders, explores the pivotal role of microglia, the brain's immune cells, in protecting, repairing, and reprogramming the brain for lifelong resilience. Dave and Dr. Perlmutter break down how microglia, the brain's resident immune cells, shift from a supportive state into a destructive one called M1, and why this shift, not amyloid plaque, may be the real driver of Alzheimer's, Parkinson's, and other neurodegenerative conditions. They dig into why the leading amyloid-clearing drugs fail to improve cognition, what a landmark JAMA study revealed about reversing cognitive decline through lifestyle intervention alone, and why a single daily serving of ultra-processed food raised Alzheimer's risk by 13 percent in a 12.7 year study. They also cover new research on GLP-1 drugs and brain inflammation, the surprising role of gum disease and oral bacteria in dementia risk, and why 40 hertz light therapy is emerging as a low-cost tool for clearing brain plaque and calming neuroinflammation. You'll Learn: Why the shift from supportive to destructive brain immune cells may be the true root cause of Alzheimer's and Parkinson's Why leading Alzheimer's drugs fail to improve cognition, and what the original research behind the amyloid hypothesis actually showed How one daily serving of ultra-processed food raises Alzheimer's risk, and what a landmark lifestyle intervention study found instead Whether GLP-1 drugs help or harm brain inflammation, based on new Parkinson's and Alzheimer's trial data How gum disease and oral bacteria are linked to dementia, and simple daily habits that reduce that risk Why 40 hertz light therapy is emerging as a tool to clear brain plaque and calm neuroinflammation How ketones, DHA, and metabolic health protect the brain after head injury Thank you to our sponsors! - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - ZenBud | Dave's Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount. - Pique | Head over to Piquelife.com/Dave to get 20% off your order. That's P-I-Q-U-E life dot com slash DAVE - PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: microglia, brain inflammation, Alzheimer's prevention, Parkinson's disease, amyloid hypothesis, neurodegeneration, GLP-1 drugs, semaglutide, ultra-processed food, gum disease and dementia, oral microbiome, 40 hertz light therapy, ketones, DHA, mitochondria, brain fog, long COVID, David Perlmutter, Brain Defenders, Grain Brain, functional medicine, biohacking, longevity, neuroplasticity Resources: • Get Dr. Perlmutter's New Book Brain Defenders: https://drperlmutter.com/books/brain-defenders/ • Learn More About Dr. Perlmutter's Work At: https://drperlmutter.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:40 – Intro 02:38 – Ultra-Processed Foods 06:34 – Are Carbs Bad? 08:48 – Alcohol & Brain Health 12:28 – Microglia & Inflammation 24:37 – Head Injury & Recovery 29:27 – Oral Bacteria & Dementia 34:08 – GLP-1s & Brain Inflammation 40:20 – 40 Hertz Light Therapy 48:35 – Air Pollution vs. Lead 50:27 – David's Closing Truth See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
This week, Scott sat down with his Lawfare colleagues Editor in Chief and co-host emeritus Benjamin Wittes and Senior Editors Anna Bower and Michael Feinberg to talk through the latest in national security news, including:“Humphrey's Executioner.” On June 29, the Supreme Court closed out its term with a trio of decisions on the president's power to fire officials at supposedly independent agencies. In Trump v. Slaughter, a 6–3 majority upheld Trump's firing of FTC Commissioner Rebecca Slaughter and overruled the 90-year-old precedent Humphrey's Executor, handing the president at-will removal power over roughly two dozen multimember agencies. The same day, in Trump v. Cook, the Court refused 5–4 to let Trump remove Federal Reserve Governor Lisa Cook, carving out a special exemption for the central bank. And a day later, in Blanche v. Perlmutter, the justices declined to let Trump oust Register of Copyrights Shira Perlmutter, whose office sits within the legislative branch. Taken together, what do these cases tell us about the unitary executive and the future of agency independence?“For Your Lies Only.” The Office of the Director of National Intelligence is in freefall. Since Bill Pulte—a housing-finance official with no intelligence background—took over as acting DNI on June 19, he has demanded a roster of every employee, fired the head of the office that oversees the President's Daily Brief, and all but liquidated the National Intelligence Council. The fight over his appointment has already cost the government its Section 702 surveillance authority, which lawmakers let lapse rather than leave in his hands, and Trump abruptly canceled the confirmation hearing for his own permanent nominee, Jay Clayton, to keep the “less shackled” Pulte in place. How did the nation's top intelligence coordinator get here—and how much damage can a politicized ODNI actually do?“Fixer Upper.” In one of the stranger turns of the Trump era, Michael Cohen—the former “fixer” whose testimony helped convict Trump of 34 felonies—says he and the president have reconciled. Cohen, who once vowed to flee the country if Trump won, said that the ice between them “didn't just melt, it broke,” and he is now taking a weekend slot on a conservative station with what he says was Trump's “glowing recommendation.” The thaw arrives as Trump's appeal of his New York conviction and related civil fraud judgment grind forward—and after Cohen publicly claimed he felt “pressured and coerced” to testify. What might Cohen's turn mean for that pending appeal?In object lessons, everyone is in a unifying mood. Ben demonstrates how RAGtime, his co-creation with AI overlord Claude to develop and analyze datasets, can find common cause between this week's co-hosts. Mike is enthusiastic about the new Criterion Collection bringing together all of Stanley Kubrick's works. Scott is reaching for perhaps humanity's greatest unifier—a certain beverage that can be enjoyed across political persuasions and coasts alike. And Anna is bringing us all to the world of personal essays with Jo Ann Beard's “The Fourth State of Matter.” To receive ad-free podcasts, become a Lawfare Material Supporter at www.patreon.com/lawfare. You can also support Lawfare by making a one-time donation at https://givebutter.com/lawfare-institute.Support this show http://supporter.acast.com/lawfare. Hosted on Acast. See acast.com/privacy for more information.
This week, Scott sat down with his Lawfare colleagues Editor in Chief and co-host emeritus Benjamin Wittes and Senior Editors Anna Bower and Michael Feinberg to talk through the latest in national security news, including:“Humphrey's Executioner.” On June 29, the Supreme Court closed out its term with a trio of decisions on the president's power to fire officials at supposedly independent agencies. In Trump v. Slaughter, a 6–3 majority upheld Trump's firing of FTC Commissioner Rebecca Slaughter and overruled the 90-year-old precedent Humphrey's Executor, handing the president at-will removal power over roughly two dozen multimember agencies. The same day, in Trump v. Cook, the Court refused 5–4 to let Trump remove Federal Reserve Governor Lisa Cook, carving out a special exemption for the central bank. And a day later, in Blanche v. Perlmutter, the justices declined to let Trump oust Register of Copyrights Shira Perlmutter, whose office sits within the legislative branch. Taken together, what do these cases tell us about the unitary executive and the future of agency independence?“For Your Lies Only.” The Office of the Director of National Intelligence is in freefall. Since Bill Pulte—a housing-finance official with no intelligence background—took over as acting DNI on June 19, he has demanded a roster of every employee, fired the head of the office that oversees the President's Daily Brief, and all but liquidated the National Intelligence Council. The fight over his appointment has already cost the government its Section 702 surveillance authority, which lawmakers let lapse rather than leave in his hands, and Trump abruptly canceled the confirmation hearing for his own permanent nominee, Jay Clayton, to keep the “less shackled” Pulte in place. How did the nation's top intelligence coordinator get here—and how much damage can a politicized ODNI actually do?“Fixer Upper.” In one of the stranger turns of the Trump era, Michael Cohen—the former “fixer” whose testimony helped convict Trump of 34 felonies—says he and the president have reconciled. Cohen, who once vowed to flee the country if Trump won, said that the ice between them “didn't just melt, it broke,” and he is now taking a weekend slot on a conservative station with what he says was Trump's “glowing recommendation.” The thaw arrives as Trump's appeal of his New York conviction and related civil fraud judgment grind forward—and after Cohen publicly claimed he felt “pressured and coerced” to testify. What might Cohen's turn mean for that pending appeal?In object lessons, everyone is in a unifying mood. Ben demonstrates how RAGtime, his co-creation with AI overlord Claude to develop and analyze datasets, can find common cause between this week's co-hosts. Mike is enthusiastic about the new Criterion Collection bringing together all of Stanley Kubrick's works. Scott is reaching for perhaps humanity's greatest unifier—a certain beverage that can be enjoyed across political persuasions and coasts alike. And Anna is bringing us all to the world of personal essays with Jo Ann Beard's “The Fourth State of Matter.” To receive ad-free podcasts, become a Lawfare Material Supporter at www.patreon.com/lawfare. You can also support Lawfare by making a one-time donation at https://givebutter.com/lawfare-institute. Hosted on Acast. See acast.com/privacy for more information.
Immune Regulation, Omega-3 Nuance, and Himalayan Tartary Buckwheat with Dr. Austin Perlmutter, chief science officer of Big Bold Health. He details immune regulation as a nuanced, multidimensional system shaped by diet and lifestyle rather than simple “boosting.” Perlmutter explains Big Bold Health's focus on immunometabolism, educating about immune complexity, and conducting studies on nutraceuticals, including use of CGMs and clinical trials. He discusses why eating fish often outperforms refined fish-oil supplements, noting conventional processing (heat, bleaching, deodorizing, esterification) and loss of other lipids and nutrients. Perlmutter highlights specialized pro-resolving mediators (resolvins, protectins, maresins) and vitamins A and D as potentially better preserved in minimally processed oils, and reviews typical omega-3 intake and target ranges. The conversation also covers immunosenescence/inflammaging and Big Bold Health research on sprouted Himalayan Tartary Buckwheat, its high polyphenols (rutin, quercetin), microbiome effects, and studies including epigenetic aging clocks and brain outcomes.
In this new episode, Crawlspace Media's Tim Pilleri and Lance Reenstierna speak with Dr.'s Sarah Schiffecker and David Perlmutter about the media circus surrounding the Karen Read case. In this episode, we explore the complex case of Karen Reed, media coverage, and the impact of technology on justice. Our experts discuss media circus, social media influence, and the evolving standards of evidence in criminal justice. Check out Dr. Schiffecker's work: https://www.depts.ttu.edu/comc/faculty/faculty/sschiffecker.php. Check out Dr. Perlmutter's work: https://www.depts.ttu.edu/comc/faculty/faculty/dperlmutter.php. Check out Quince: https://quince.com/MISSING. Check out Mint Mobile: mintmobile.com/missing. Check out Kensington Publishing: https://www.kensingtonbooks.com. Main podcast theme by Kevin Macleod. Check out his work at https://incompetech.com/. Additional music by David Williams. See his work at http://williamsflutes.com. Follow Missing: IG: https://www.instagram.com/MissingCSM/. Youtube: https://www.youtube.com/missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Sci-fi has taken many forms as a genre, and since it happens to be a genre that both Dr. Perlmutter and Chris have an affinity for, why not cover one of the true classics. While those who saw Forbidden Planet in theaters may not have realized that it was merely an amuse bouche for the more pop culture pliable Star Trek, the film is definitely one worth talking about and reappraising from a modern-day perspective.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-kulturecast--2883470/support.
The countdown reaches the most divisive Avengers title. Adam makes the case that Avengers: Age of Ultron isn't a bad movie so much as a conflicted one, the first Marvel tentpole that put serving the wider universe ahead of being its own thing. Along the way: the tonal whiplash that kills every death scene, the Whedon dialogue problem, and a deep dive into how the Agents of SHIELD and Inhumans experiment, a Perlmutter mandate born of X-Men envy, was the original dry run for the "homework" problem that would later sink the Multiverse Saga. A solid but bottom-of-the-Avengers 4 out of 5. Next week: Civil War.
We're running it back with some films we've already watched with a Robert Eggers film that has become a modern day classic: The VVitch. Starring Anya-Taylor Joy as Thomasin, she along with her family live in 1630s New England which may or may not be under the sway of a witch in the woods. Thomasin and her family are doomed to find out whether or not the witch is real or not. Dr. David. D. Perlmutter and Julie Brannan join the episode to talk all about it.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-kulturecast--2883470/support.
Why They Disappeared: Coping with Ghosting & Betrayal with Gretta PerlmutterHave you ever been left on "read" forever? In modern dating, few things are as frustrating or painful as a sudden, unexplained ending. In this episode of the Cupid's Coach Podcast, host Julie Ferman welcomes Gretta Perlmutter, a Certified Post Betrayal Transformation® Coach and host of the Coping With Ghosting podcast. Gretta shares her professional expertise and personal journey through "ghosting on repeat" to help you understand why people disappear and how to reclaim your peace of mind.Julie and Gretta break down the distinction between breaking a "social contract" and healthy self-protection, while exploring the surprising statistics that show ghosting is a multi-generational trend. Whether you're dealing with a "micro-ghost" on an app or a disappearance after a real date, this episode provides the courageous communication tools you need to move from victimhood to closure.Inside this Episode:Defining Ghosting: Why withdrawing without explanation is different from leaving an abusive situation.The Ghosting Stats: A look at why women (55%) are actually more likely to admit to ghosting than men (46%).Accidental vs. Intentional: Distinguishing between a lost phone and a lack of moral fiber or vulnerability.The "Obituary" Phase: Moving past the urge to Google why they stopped texting.Courageous Communication: Practical scripts for checking in on a date and how to end things respectfully.The Healing Journey: Why your value doesn't depend on a ghost's approval.Connect with Gretta Perlmutter: Explore resources and coaching at CopingWithGhosting.com.Connect with Julie Ferman: Ready to find a person who will never ghost you? Register for free matchmaking at JulieFerman.com.#CupidsCoach #GrettaPerlmutter #Ghosting #BetrayalHealing #DatingAdvice #RelationshipBetrayal #Closure #PostBetrayalTransformation
In this episode, Crawlspace Media's Tim Pilleri & Lance Reenstierna are joined by Dr. Sarah Schiffecker & Dr. David Perlmutter to try to solve the coldest murder in history. The discussion takes them back 5,300 years to the Italian Alps, where the legendary Ötzi became the victim of the worlds oldest documented murder. This conversation centers around questions of motive, means and opportunity. This episode was previously published on Crawlspace on March 29th, 2026. More on Ötzi: https://en.wikipedia.org/wiki/Ötzi. Check out Dr. Schiffecker's work: https://www.depts.ttu.edu/comc/faculty/faculty/sschiffecker.php Check out Dr. Perlmutter's work: https://www.depts.ttu.edu/comc/faculty/faculty/dperlmutter.php Check out Quince: https://quince.com/MISSING. Check out Mint Mobile: mintmobile.com/missing. Main podcast theme by Kevin Macleod. Check out his work at https://incompetech.com/. Additional music by David Williams. See his work at http://williamsflutes.com. Follow Missing: IG: https://www.instagram.com/MissingCSM/. Youtube: https://www.youtube.com/missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Episode 3250 of the Vietnam Veteran News Podcast will feature a story about Vietnam Vet Leo Perlmutter finally receiving his medals for the Vietnam War. The featured story is titled: Delayed Purple Heart Awarded To Vietnam Veteran It appeared on … Continue reading → The post Episode 3250 – Vietnam Vet Leo Perlmutter finally received his Vietnam Medals first appeared on Vietnam Veteran News.
In this new episode, Crawlspace Media's Tim Pilleri and Lance Reenstierna speak with Dr's Sarah Schiffecker and David Perlmutter from Texas Tech University about the mysterious disappearance of Air Force General William Neil McCasland from his home in Albuquerque, New Mexico on February 27th, 2026. If you have any information in General McCasland's disappearance, please text BCSO to 847411 or call 505-468-7070. Dr. Schiffecker's faculty page: https://www.depts.ttu.edu/comc/faculty/faculty/sschiffecker.php. Dr. Perlmutter's faculty page: https://www.depts.ttu.edu/comc/faculty/faculty/dperlmutter.php. Check out Quince: https://quince.com/MISSING. Check out Mint Mobile: mintmobile.com/missing. We have an upcoming live show with Another F*cking Horror Podcast! It's called Criminally Stupid - The Search For the World's Dumbest Criminal. For tickets, go to: https://www.eventbrite.com/e/criminally-stupid-the-search-for-the-worlds-dumbest-criminal-tickets-1984625623665. Main podcast theme by Kevin Macleod. Check out his work at https://incompetech.com/. Additional music by David Williams. See his work at http://williamsflutes.com. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr is joined by renowned neurologist and bestselling author Dr. David Perlmutter to explore one of the most important breakthroughs in brain health — the role of microglia. Often overlooked, microglial cells are the brain's immune system and play a central role in determining whether the brain thrives or degenerates over time. Dr. Perlmutter explains how these cells can shift between protective (M2) and destructive (M1) states — and how this shift underlies neurodegenerative diseases like Alzheimer's, Parkinson's, and more. Most importantly, this episode highlights how everyday lifestyle choices — from diet and exercise to metabolic health — directly influence brain function and long-term cognitive resilience. Join us as we delve into: What microglia are and why they control brain health The difference between M1 (destructive) and M2 (protective) states How metabolism shapes the brain's immune response Why conditions like Alzheimer's are rooted in immune dysfunction The connection between blood sugar, insulin, and brain degeneration This episode is for you if: You want to protect your brain and prevent cognitive decline You're interested in the science of Alzheimer's and neurodegeneration You want actionable strategies to improve brain health You're curious about the future of brain optimization and longevity You can also find this episode on… Youtube: https://youtu.be/EMrlchMOZKk Find more from Dr. David Perlmutter Website: https://www.drperlmutter.com Book: https://braindefenders.com LinkedIn: https://www.linkedin.com/in/david-perlmutter-md/ Instagram: https://www.instagram.com/davidperlmutter/ Facebook: https://www.facebook.com/DavidPerlmutterMd/ Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
Welcome back to Crawlspace. In this new episode, Tim Pilleri & Lance Reenstierna are once again joined by Dr. Sarah Schiffecker & Dr. David Perlmutter. Their conversation takes them back 5,300 years to the Italian Alps, where the legendary Ötzi became the victim of the worlds oldest documented murder. After his discovered in 1991, the questions of motive, means and opportunity remain an elusive enigma. WE HAVE A LIVE SHOW WITH THE SHOW, ANOTHER F*CKING HORROR PODCAST. IT'S CALLED: CRIMINALLY STUPID - THE SEARCH FOR THE WORLDS DUMBEST CRIMINAL. FOR TICKETS, GO TO: https://www.eventbrite.com/e/criminally-stupid-the-search-for-the-worlds-dumbest-criminal-tickets-1984625623665 Check out Dr. Schiffecker's work: https://www.depts.ttu.edu/comc/faculty/faculty/sschiffecker.php Check out Dr. Perlmutter's work: https://www.depts.ttu.edu/comc/faculty/faculty/dperlmutter.php Check out Quince: https://quince.com/MISSING. The music for Crawlspace was produced by David Flajnik. Listen to his music here: https://www.pond5.com/artist/bigdsound. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Private Investigations For the Missing Please donate if you can: https://investigationsforthemissing.org/. http://piftm.org/donate. https://twitter.com/PIFortheMissing. https://www.facebook.com/PIFortheMissing/. https://www.instagram.com/investigationsforthemissing/. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. David D. Perlmutter and Julie Brannan return to lend their insights into the 2025 conspiracy film Bugonia. This movie has so many references to modern day conspiracy culture, it takes the three of us to unpack!
One of the most polarizing questions in the mind of any photographer is "Should—or shouldn't I—get an agent?" The role of an agent in a photographer's career is often misunderstood, leading hungry creatives to think that securing representation is their number one key to success. In truth, the relationship between a photographer and agent is far more nuanced than simply booking more assignments. In today's podcast, we take a deep dive into this complex alliance in a discussion with two generations of top agents, whose combined careers span from the film-era to the latest in media buys. Listen in for a behind-the-scenes look at the many details involved, from the four P's Jennifer (JP) Perlmutter looks for in a photographer's work to Michael Ash's skill in editing a portfolio to allow a photographer's individual vision and passion to shine. Our experts also shed light on critical topics such as branding, while making distinctions between a physical and emotional brand. Get fresh insights about standing out in an oversaturated marketplace and the matter of seeing ahead of the curve on trends. As JP notes, "You don't have to hop on the current trend. You don't need to create the new trend. You need to create what's true to you, what's true to your vision, and then know that there are enough people out there—that there is your niche. There are the people who are going to love what you're doing." Guests: Jennifer Perlmutter & Michael Ash Episode Timeline: 3:16: Is there a difference between the terms agent and rep? 4:11: Michael Ash on his start as an agent in late 1970's New York. 7:46: Jennifer Perlmutter talks about her beginnings at the dawn of social media. 12:25: Having a good eye for talent, plus the qualifications and skillsets needed to be a rep. 16:54: Producing as part of an agent's role, plus a peek inside relationships between photographers and a rep. 20:16: Navigating connections between clients, photographers, and reps—plus contracts. 27:34: An agent's role in protecting a photographer's interests, plus their skill in editing and curating the work. 35:46: JP describes the Four P's—what she looks for in a photographer's work. 43:14: Episode Break 44:36: To brand or not to brand, plus distinctions between physical and emotional branding. 47:28: How do you stand out in an oversaturated marketplace and hone a unique vision? 53:29: The current trend for nostalgia and harkening back to the analog world. 57:56: Michael and JP discuss today's advertising marketplace and usage rates. 1:01:08: The matter of taste vs analytics in today's commercial marketplace. 1:04:21: How do you see ahead of the curve or know which trends are worth jumping on? Where do we go from here? 1:11:14: Apostrophe's mentorship program, advice for young creatives, and some thoughts on AI. Guest Bios: Michael Ash is a photographers' agent and creative consultant who began representing photographers in 1979, after failing to get drafted into Major League Baseball. Born in Brownsville, Brooklyn, and raised on the streets of New York, Michael founded and led a successful agency in New York City from 1979 to 2016, focused on guiding the careers of more than 40 photographers from around the globe. He introduced this international talent to the world of commercial photography through representation, creative direction, and mentorship. Michael is an expert in contract negotiation, editorial curation, and client development. Most importantly, he has a lifelong dedication to nurturing artistic vision and unique creativity. Jennifer "JP" Perlmutter is currently a senior photo and motion rep at Apostrophe, with nearly two decades of experience representing and producing for photographers and directors across commercial and editorial realms. A 2006 graduate of Emerson College, where she studied advertising and visual arts, JP fell in love with photography early on and built a career at the intersection of creativity and commerce. She's known for her collaborative approach, sharp production insight, and deep commitment to artist development, especially when it comes to mentoring emerging talent. Possessing a robust skill set that includes artist representation, marketing strategy, photography, print production, social media and more, JP has built meaningful connections between artists, agencies, and brands, helping creatives collaborate authentically and thrive. She's passionate about championing visual storytellers and creating space for new voices in an ever-evolving industry. Stay Connected: Michael Ash on Instagram: https://www.instagram.com/michaelash_original/ Michael Ash on LinkedIn: https://www.linkedin.com/in/michaelash2/ Jennifer Perlmutter on Instagram: https://www.instagram.com/jnperl/ Jennifer Perlmutter on LinkedIn: https://www.linkedin.com/in/jperlmutter/ Apostrophe Reps Website: https://apostrophe.is/ Apostrophe Reps on Instagram: https://www.instagram.com/apostrophereps/ Credits: Host: Derek Fahsbender Senior Creative Producer: Jill Waterman Senior Technical Producer: Mike Weinstein Executive Producer: Dana Glidden
Welcome back to Crawlspace. In this new episode, Tim Pilleri & Lance Reenstierna are joined by friend of the show, Dr. David Perlmutter and new friend of the show Dr. Sarah Schiffecker. The two break down the nuances of the recent tragedy that occurred near the summit of Austria's highest mountain, Grossglockner. How does a culture rich in climbing and conquering these majestic heights, come to terms with toxic masculinity, national pride and willful neglect? Video of Grossglockner lights courtesy of: https://www.wcvb.com/article/austria-grossglockner-manslaughter-sentence/70430714 Check out Dr. Schiffecker's work: https://www.depts.ttu.edu/comc/faculty/faculty/sschiffecker.php Check out Dr. Perlmutter's work: https://www.depts.ttu.edu/comc/faculty/faculty/dperlmutter.php Check out Quince: https://quince.com/MISSING. The music for Crawlspace was produced by David Flajnik. Listen to his music here: https://www.pond5.com/artist/bigdsound. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Private Investigations For the Missing Please donate if you can: https://investigationsforthemissing.org/. http://piftm.org/donate. https://twitter.com/PIFortheMissing. https://www.facebook.com/PIFortheMissing/. https://www.instagram.com/investigationsforthemissing/. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
We welcome Dr. Alexis Perlmutter of Perlmutter Dermatology, a physician-owned, private practice in Delmar, New York. Dr. Perlmutter specializes in both Pediatric and Adult Dermatology, as well as Dermatology Surgery. Ray Graf hosts.
Welcome to the Prehospital Emergency Care Journal Podcast! In this Deep Dive episode, host Maia Dorsett speaks with Aaron E. Robinson, Sarah K. S. Knack, and Michael C. Perlmutter about their paper, Trends in Prehospital First-Attempt Use of Supraglottic Airways in Non-Cardiac Arrest Patients: A Descriptive Study. The conversation explores how airway management in EMS may be evolving, including growing interest in supraglottic airways as a first-line approach rather than solely a rescue device. The authors discuss key airway concepts—such as RSI, DSI, and rapid sequence airway—and review what their national dataset reveals about current practice patterns. Along the way, they examine variations in medication strategies, including the continued use of sedation-only approaches and airway placement without neuromuscular blockade or medications. The discussion raises important questions about how EMS clinicians balance speed, safety, and skill maintenance when managing critically ill airways in the field. Featured Article Robinson, A. E., Knack, S. K. S., Driver, B. E., Prekker, M. E., Perlmutter, M. C., Bunting, A. J., … Puskarich, M. A. (2026). Trends in Prehospital First-Attempt Use of Supraglottic Airways in Non-Cardiac Arrest Patients: A Descriptive Study. Prehospital Emergency Care, 1–8. https://doi.org/10.1080/10903127.2025.2593579 As always THANK YOU for listening. Hawnwan Philip Moy MD (@pecpodcast) Scott Goldberg MD, MPH (@EMS_Boston) Jeremiah Escajeda MD, MPH (@jerescajeda) Joelle Donofrio-Odmann DO (@PEMems) Maia Dorsett MD PhD (@maiadorsett) Lekshmi Kumar MD, MPH(@Gradymed1) Greg Muller DO (@DrMuller_DO) Ariana Weber MD (@aweberMD4) Rebecca Cash PhD (@CashRebeccaE) Michael Kim MD (@michaeljukim) Rachel Stemerman PhD (@steminformatics) Nikolai Arendovich MD
Anthropic claque la porte du Pentagone, OpenAI récupère le contrat : l'IA s'invite au cœur des tensions géopolitiques. Pendant ce temps, Apple dégaine de nouveaux produits et le Mobile World Congress dévoile les innovations qui façonneront la tech de demain.
In this new episode, Crawlspace Media's Tim Pilleri & Lance Reenstierna are joined once again by friend of the show and expert in all things media + crime related, Dr. David Perlmutter. As the clock continues to tick on the abduction of Nancy Guthrie, Dr. Perlmutter helps to break down how the media releases information, what is important for the public to know and what's important for the public to not know. If you have any information please submit a tip to the FBI at 1-800-225-5324. You could also submit a tip here: https://tips.fbi.gov/home. More info: https://www.fbi.gov/wanted/kidnap/nancy-guthrie. Savannah's Instagram video: https://www.instagram.com/p/DUW3mpqD8qd. Check out Quince: https://quince.com/MISSING. Main podcast theme by Kevin Macleod. Check out his work at https://incompetech.com/. Additional music by David Williams. See his work at http://williamsflutes.com. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome back to Crawlspace. In this new episode, Tim Pilleri & Lance Reenstierna are joined once again by friend of the show and expert in all things media + crime related, Dr. David Perlmutter. As the clock continues to tick on the abduction of Nancy Guthrie, Dr. Perlmutter helps to break down how the media releases information, what is important for the public to know and what's important for the public to not know. Nancy Guthrie was taken from her home in Catalina Foothills, Arizona on February 1st, 2026. Nancy is the mother of well known broadcaster Savannah Guthrie. If you have any information please submit a tip to the FBI at 1-800-225-5324. You could also submit a tip here: https://tips.fbi.gov/home. More info: https://www.fbi.gov/wanted/kidnap/nancy-guthrie. Savannah's Instagram video: https://www.instagram.com/p/DUW3mpqD8qd. Check out Quince: https://quince.com/MISSING. The music for Crawlspace was produced by David Flajnik. Listen to his music here: https://www.pond5.com/artist/bigdsound. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Most brain decline, mood instability, and impulsive behavior start with a breakdown in how the brain's immune cells produce and use energy. This episode shows how mitochondrial health inside microglia influences cognition, emotion, and long-term brain resilience, and how everyday inputs quietly push those systems toward damage or repair. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Dr. David Perlmutter, a board-certified neurologist and six-time New York Times bestselling author whose work focuses on the intersection of neurology, nutrition, metabolism, and brain health. A Fellow of the American College of Nutrition and member of the Editorial Board of the Journal of Alzheimer's Disease, Dr. Perlmutter brings decades of clinical and research experience to this conversation on how inflammation and mitochondrial function shape the brain across the lifespan. Together, they explore how microglial cells shift their behavior based on metabolic conditions, and how those shifts influence neurodegeneration, emotional regulation, impulse control, and cognitive performance. The discussion covers real-world inputs that shape these systems, including sleep optimization, fasting, ketosis, glucose regulation, gut signaling, environmental toxins, and tools referenced in the episode such as red and infrared light, 40 Hz light and sound, hyperbaric oxygen, lithium, nicotine, supplements, nootropics, GLP-1 agonists, and dietary approaches like carnivore and ketosis. The conversation connects brain biology to lived experience, showing how metabolism influences behavior, decision making, and long-term human performance through a Smarter Not Harder lens. You'll Learn: • How microglia shift between supportive and destructive states and why metabolism drives that change • How mitochondrial function inside immune cells influences inflammation and brain resilience • How inflammation affects the prefrontal cortex, impulse control, and reward-driven behavior • What the episode says about GLP-1 agonists and behavior changes like reduced cravings and gambling • How gut-derived signaling and short-chain fatty acid balance (butyrate vs propionate) relates to brain function • How tools like red and infrared light, hyperbaric oxygen, and 40 Hz light and sound connect to microglia • The lifestyle levers discussed in the episode: sleep optimization, fasting, ketosis, glucose control, and toxin reduction • The compounds mentioned, including lithium, nicotine, urolithin A, CoQ10, rosmarinic acid, and dihydromyricetin Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Establish a powerful foundation for sustained wellness with Pique. Unlock 20% off: piquelife.com/DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: microglia brain health, brain immune system mitochondria, neuroinflammation podcast, mitochondrial dysfunction brain, david perlmutter podcast, dr david perlmutterneurologist, grain brain author podcast, alzheimers brain metabolism, parkinsons microglia, autism brain inflammation, gut brain immune signaling, short chain fatty acids brain, butyrate propionate brain, glp-1 brain behavior, glp-1 addiction research, red light therapy brain, infrared light mitochondria brain, 40 hz light sound brain, hyperbaric oxygen brain health, lithium microglia brain Resources: • Learn More About Dr. Perlmutter at: https://drperlmutter.com/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 - Introduction 1:45 - Autism Spectrum 4:38 - Alzheimer's & Beta Amyloid 7:02 - Brain Immune Cells 8:06 - GLP-1 & Parkinson's 10:44 - M1 vs M2 Microglia 13:08 - Pharmaceutical Microdosing 15:51 - Gene Therapy 19:09 - Mold & Toxins 21:58 - Environmental Pollution 26:05 - MPTP Discovery 29:07 - Healing Interventions 31:39 - Light & Sound Therapy 36:35 - Mitochondrial Function 44:57 - Inflammation & Prefrontal Cortex 48:00 - GLP-1 Global Impact 52:11 - Mitochondrial Community 56:05 - Consciousness & The Field 1:00:00 - Psychedelics 1:01:59 - Love & Judgment 1:06:35 - Death & Knowing 1:09:06 - Heart-Brain Connection 1:11:06 - Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dr. David D. Perlmutter gets promoted to the role of acting co-host and Julie Brannan joins us to talk about Apple TV's Pluribus and its more interesting conspiracy and conspiracy adjacent aspects.
Welcome to Crawlspace. In this new episode, Tim Pilleri & Lance Reenstierna are again joined old friend of the show, Dr. David Perlmutter. The topic this week is trying to understand the killings of Brown University students Mukhammad Aziz Umurzokov and Ella Cook & MIT professor Dr. Nuno Loureiro. Check out Dr. Perlmutter's work: https://www.depts.ttu.edu/comc/faculty/faculty/dperlmutter.php Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Private Investigations For the Missing Please donate if you can: https://investigationsforthemissing.org/. http://piftm.org/donate. https://twitter.com/PIFortheMissing. https://www.facebook.com/PIFortheMissing/. https://www.instagram.com/investigationsforthemissing/. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to Crawlspace. In this new episode, Tim Pilleri & Lance Reenstierna are joined by old friend of the show, Dr. David Perlmutter. The three of them discuss the horrific murders of Rob Reiner and his wife, Michele Singer Reiner at the hands of their son Nick. Dr. Perlmutter is a professor of Media & Communications at Texas Tech University. Check out Dr. Perlmutter's work: https://www.depts.ttu.edu/comc/faculty/faculty/dperlmutter.php Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Private Investigations For the Missing Please donate if you can: https://investigationsforthemissing.org/. http://piftm.org/donate. https://twitter.com/PIFortheMissing. https://www.facebook.com/PIFortheMissing/. https://www.instagram.com/investigationsforthemissing/. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Today we are revisiting a Berkeley Talks episode in which a cross-disciplinary panel of UC Berkeley professors, whose expertise ranges from political science to philosophy, discuss how they view decision-making from their respective fields, and how we can use these approaches to make better, more informed choices. Panelists include: Wes Holliday, professor of philosophy. Holliday studies group decision-making, including the best methods of voting, especially in the democratic context. Marika Landau-Wells, assistant professor of political science. Landau-Wells studies the effect that threat perception has on national security decision-making, and how some decisions we make to protect ourselves can endanger many others.Saul Perlmutter, Franklin W. and Karen Weber Dabby Professor of Physics and 2011 Nobel laureate. Perlmutter co-teaches a Big Ideas course, called Sense and Sensibility and Science, designed to equip students with basic tools to be better thinkers by exploring key aspects of scientific thinking.Linda Wilbrecht, professor of neuroscience and psychology. An adolescent scientist, Wilbrecht studies how adolescent learning and decision-making changes from ages 8 to 18, and how it compares to that of adults and children. Jennifer Johnson-Hanks, executive dean of the College of Letters and Science (moderator).The campus event was held on Oct. 9, 2024, as part of the College of Letters and Science's Salon Series, which brings together faculty and students from a swath of disciplines to interrogate and explore universal questions or ideas from disparate perspectives.Watch a video of the discussion.Listen to the episode and read the transcript on UC Berkeley News (news.berkeley.edu/podcasts/berkeley-talks).Music by HoliznaCC0.Photo by Vladislav Babienko via Unsplash. Hosted on Acast. See acast.com/privacy for more information.
My favorite professor of Communications Dr. David D. Perlmutter returns to expand on his idea of low effort conspiracy culture and its infiltration into almost all aspects of our lives with the aid of AI!
Nutritionist Leyla Muedin focuses on a new perspective in Alzheimer's research, particularly the role of microglial cells. She reveals insights from integrative neurologist Dr. David Perlmutter's presentation at the Integrative Healthcare Symposium, emphasizing the significance of microglial cells in Alzheimer's disease. The discussion highlights the traditional focus on beta amyloid plaques and introduces the importance of shifting from the M1 pro-inflammatory phenotype to the M2 anti-inflammatory phenotype of microglial cells. Dr. Perlmutter advocates for addressing systemic metabolic and inflammatory issues, pointing out factors like poor diet, lack of sleep, and high blood sugar, which are crucial in preventing Alzheimer's. The episode delves into lifestyle interventions such as ketogenic diets, fasting, and nutritional impacts to manage and potentially reverse the detrimental shift in microglial behavior.
Katherine Forrest and Scott Caravello unpack the litigation in Thaler v. Perlmutter over whether purely AI-generated works can be copyrighted and analyze the Getty v. Stability ruling in the UK on AI model training and copyright infringement. ## Learn More About Paul, Weiss's Artificial Intelligence practice: https://www.paulweiss.com/industries/artificial-intelligence
Today, I am thrilled to connect with Dr. Austin Perlmutter, a board-certified internal medicine physician, New York Times bestselling author, researcher, educator, podcaster, and entrepreneur. He is on a mission to help people get their brains unstuck for better mental and cognitive health. In our conversation today, we explore brain inflammation and its connection to longevity, the differences between acute and chronic inflammation, the influence of environmental factors, and how exposure to negative news and biases can elevate stress and affect our brain health. We examine how consumer culture promotes stress and disconnection, and we unpack the immune-metabolic effects of estrogen and its impact on neuroplasticity and our ability to learn. We also focus on the role of nutrition and nutraceuticals, and we discuss the relationship between the brain, gut, and the vagus nerve. This discussion with Dr. Austin Perlmutter is rich and insightful, and I look forward to welcoming him back for further exploration into the science and research. IN THIS EPISODE, YOU WILL LEARN: Why brain inflammation becomes an issue for many women as they navigate middle age and beyond How inflammation leads to constant changes in our cognitive and mental state Various environmental factors and other inputs that could influence brain inflammation Some easy ways to positively impact your brain health and cognition How chronic stress affects the brain How the gut microbiome and the gut immune system influence cognitive and mental health The long-term health benefits of avoiding processed foods and following a Mediterranean diet The importance of being conscientious and purposeful about the quality of the foods you eat Dr. Perlmutter shares easy and cost-effective ways to improve your cognitive, mental, and overall health Bio: Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, published researcher, and a leading expert on how lifestyle and environmental factors impact mental health. His mission is to help people reclaim their mental and physical health by addressing the biological basis of “stuckness” that disrupts brain function and emotional balance. He is a co-producer of the Alzheimer's: The Science of Prevention series and the host of the Better Brain Blueprint series, where he provides actionable strategies to support brain resilience. Dr. Perlmutter currently serves as the Managing Director at Big Bold Health, a food-as-medicine company focused on helping people rejuvenate health through better immune function, where he has published a pioneering study exploring the effects of plant nutrients on human aging through epigenetics. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Austin Perlmutter On his website On social media: @draustinperlmutter Find out more about the research on immuno-metabolism pathways Big Bold Health on social media: @bigboldhealth
Most people track glucose or ketones, but almost no one is measuring the hidden signal that could be silently wrecking your metabolism, brain function, and longevity: uric acid. This episode reveals why this overlooked biomarker drives obesity, diabetes, cardiovascular disease, Alzheimer's, and even accelerated aging—and how you can hack it to unlock resilience, human performance, and smarter not harder health upgrades. Watch the podcast on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR We revisit host Dave Asprey sitting down with Dr. David Perlmutter, one of the world's leading functional medicine neurologists and the #1 New York Times bestselling author of Grain Brain and Drop Acid. Dr. Perlmutter has spent decades connecting gut health, brain optimization, and neuroplasticity with lifestyle interventions that truly change the trajectory of disease. In this conversation, he explains how uric acid acts as a metabolic switch that determines whether you burn fat or store it, whether your mitochondria power you up or slow you down, and whether your brain stays sharp or declines with age. They break down how fructose, purines, alcohol, and even dehydration spike uric acid, why Japan is decades ahead in using this as a health marker, and how supplements like quercetin and luteolin rival pharmaceuticals in keeping it under control. You'll also learn how ketosis, fasting, cold therapy, carnivore and plant-based approaches, and sleep optimization all interact with uric acid to shape your healthspan. This is biohacking at its most actionable—because once you measure this signal, you can control it, and once you control it, you radically upgrade your metabolism, your brain, and your longevity. This is essential listening for anyone serious about hacking their biology, building neuroplasticity, powering up mitochondria, exploring nootropics, and discovering smarter not harder ways to live longer and perform better. You'll Learn: • Why uric acid may be the most important overlooked biomarker for longevity • How it connects obesity, diabetes, cardiovascular disease, and Alzheimer's • The evolutionary reason your body uses uric acid as a survival signal • How fructose and hidden sugars sabotage metabolism and brain optimization • The role of quercetin, luteolin, and targeted supplements in lowering uric acid • Why measuring at home with a simple device can change your health trajectory • How functional medicine uses uric acid as a predictive tool for chronic disease Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: uric acid longevity, uric acid metabolism, fructose uric acid pathway, xanthine oxidase inhibition, quercetin uric acid, luteolin supplements, AMP kinase uric acid, AMP deaminase metabolism, uric acid and mitochondria, uric acid and neuroplasticity, uric acid Alzheimer's risk, uric acid dementia prevention, uric acid and nitric oxide, fructose metabolism hibernation biology, evolutionary mismatch uricase mutation, fructokinase inhibition, uric acid and insulin resistance, gout biohacking, uric acid and obesity, uric acid functional medicine Resources: • David's Website: https://drperlmutter.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:35 — Introduction 2:26 — Why Uric Acid Matters 5:55 — Measuring Uric Acid 8:17 — Disease Risk 9:38 — Metabolism Disruption 15:59 — What Raises Uric Acid 26:20 — Global Research 29:50 — Gut & Inflammation 32:55 — Seasonal Eating 47:36 — Brain Health 56:38 — Supplements & Testing 61:45 — The LUV Diet 71:41 — Closing Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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