Podcasts about rhythmia

Dr. Jeff McNairy, Psy.D., M.P.H., and Chief Medical Officer at Rythmia, has worked in the healthcare field for 25 years. He has worked in various medical environments and has seen the struggle individuals have when actually trying to heal. Through Dr. McNairy's intense experience with the most desperate patient populations (addition, acute mental health, and trauma), he has seen that the only real healing can come from within with the transformative potential of Ayahuasca when combined with medical expertise and modern therapies. Learn more about your ad choices. Visit megaphone.fm/adchoices

For the penultimate episode of season two: belonging, hosts Lauren McQ and Rebecca Rush retreat into the wide world of psychedelics as medicine with special guest Brittany Wilson of Original Instruction School. Brittany is an herbalist and midwife who has lived with indigenous cultures in South America and has been leading ayahuasca retreats for over a decade. The ladies discuss how most plant medicine doesn't get you high, tech bros, the dubious backgrounds of white shamans, Rhythmia in Costa Rica, and group dynamics.   On Patreon, Rebecca interviews Rosemary Gladstar, mother of modern herbalism and founder of California School of Herbal Studies.    

Discover 9 powerful types of spirit guides that I work with regularly and how you can easily call on them for help in your life too! EXCITING NEWS to share with you all! I'll be teaching a workshop at Rythmia and participating in plant medicine ceremonies this upcoming August 2021. I'll be teaching there in the week of Aug 1st- Aug 8th, 2021 so if you want to join me in Costa Rica in August, check this link to learn more about Rhythmia and how you can join me! https://rythmia.link/lopesevent ----------------------

Learn what it actually means to be yourself, why it's crucial for you to be authentic in these new energies, and how to be yourself in 4 easy steps. EXCITING NEWS to share with you all! I'll be teaching a workshop at Rythmia and participating in plant medicine ceremonies this upcoming August 2021. I'll be teaching there in the week of Aug 1st- Aug 8th, 2021 so if you want to join me in Costa Rica in August, check this link to learn more about Rhythmia and how you can join me! https://rythmia.link/lopesevent -------------------- WORKBOOK

Learn what emotional triggers are from a spiritual perspective, where they come from, and how to heal them quickly in 4 easy steps. EXCITING NEWS to share with you all! I'll be teaching a workshop at Rythmia and participating in plant medicine ceremonies this upcoming August 2021. I'll be teaching there in the week of Aug 1st- Aug 7th, 2021 so if you want to join me in Costa Rica in August, check this link to learn more about Rhythmia and how you can join me! https://rythmia.link/lopesevent -------------------- WORKBOOK

Nicole is a transformational breathwork facilitator. The sessions I've had with her have been extremely powerful & transformative & I'm so happy to have her on the pod! In this episode Nicole shares her story & the art & science of conscious breathing.   Topics of Discussion: How transformational breathwork changed her life How the physical, mental, spiritual & emotional bodies are related & effected by our breath The science of body mapping What to expect in a breathwork session The breath, body & belief connection Creating a breath work program at Rhythmia in Costa Rica And so much more   Nicole's Website Nicole's Instagram Nicole's YouTube Channel   If you enjoyed this episode & want to support the show please share with a friend or loved one and/or subscribe, rate & review. Your support is so helpful & I'm so grateful!   Support the show by making a monthly donation on Patreon Cortney's Instagram The Unique Way Podcast Instagram Cortney's Website   Sign up for my weekly newsletter & get free access to my Human Design Masterclass. This newsletter is my fav place to connect & are always packed with free yoga classes, fav products, upcoming events, playlists, new podcasts, etc..

In Part 2 of the podcast, Cassandra delves further into her self discovery while at Rhythmia.  As you may know, Cassandra has done a lot of work that relates to her loss, but this was a whole other level she didn’t expect. Up until that point on the night of the very first ceremony, Cassandra focused more on ayahuasca as a drug rather than a medicine. But as she got there, her mind was set at ease and a lot of her anxieties, after watching how these group of humans interact and the amount of respect, love, and admiration that they have for the plant, was released. Well, there was still a bit of anxiousness left but not to the point that she’d turn around and run. The three days she was there were different experiences on each day. Continue listening to this episode to hear a more personal and detailed experience of Cassandra’s stay at Rhythmia, the Ayahuasca Ceremony, and what she felt after everything. Also, Cassandra mentions that there are new things to expect for this podcast, so if you’re curious listen on.Key Points From This Episode:Detailed experience during the retreat at RhythmiaExperience with Ayahuasca CeremonyChat about breathwork The 4 different ways ayahuasca will speak to peopleTalks about her celestial surgeriesMentions her 2 intentions she wants to focus onGetting into higher states of consciousness without using plant medicine Something new to comeTweetables:“Different levels of consciousness and different levels of connection with higher self can be done just from being present.” -Cassandra Shuck“I see this as being a coming of age ceremony…and experience for kids and teenagers who are stepping into who they’re supposed to be and trying to figure that out.” -Cassandra Shuck“When you’re on a spiritual path there are so many things lining up for you. And there are so many things working in your favor if we allow ourselves to see them.” -Cassandra ShuckMentioned links:Cassandra ShuckRhythmia Life Advancement CenterCassandra Shuck’s Rhythmia Link:  877-835-1811Stacked Against Episode 1

Welcome to Detox for Vibrant Health, This show is all about simple ways to detox your body, mind and environment so you can reclaim your vibrant health and live the life of your dreams. I’m your host Jessica Green, board certified holistic health coach, detoxification specialist and sustainable building expert. Today I have Sandra Possing joining me from Northern California. Sandra is a speaker and mindset coach. She empowers high achieving, sensitive women to develop unshakeable self belief and manifest their dream lives. The focus of today's episode is about detoxing and decluttering your mindset, emotional detoxing and also streamlining your life so you can focus on what’s important rather than being distracted. Who doesn't want this?! This was such a fun interview and here are her top tips for shifting your mindset. 1. Awareness - Be aware of the thoughts your thinking then forgive yourself for the thought. When you do this you take the power out of it. 2. Chose a different, slightly better thought 3. Notice if your thoughts feel expansive (excitement) or contracting (fear) Join Sandra for her Uplevel Your Life in 39 Days program here. This program is all about "me time". You can connect with Sandra on Facebook at https://www.facebook.com/sandrapossinglifecoach/ And on Instagram at https://www.instagram.com/sandrapossing/ References mentioned in this podcast Brene Brown - You can find her works here https://brenebrown.com/blog/2019/04/26/book-read-first/ Wim Hof Method - All about breath work and cold therapy https://www.wimhofmethod.com Plant Medicine - Check out Rhythmia retreats for a deep dive https://www.rythmia.com Brooke Castillo from Life Coach School https://thelifecoachschool.com Byron Katie The Work https://thework.com Gabby Bernstein - Her website is filled with resources https://gabbybernstein.com Denise Duffield - Inspiration for manifesting and business https://www.luckybitch.com Have you been struggling with achieving your vibrant health? The most successful women always know when to ask for help. That's what I'm here for. Book a chat with me today! https://p.bttr.to/2VI5WSW

Hello Gorgeous Souls! On today’s episode of the Manifestation Babe podcast, I will be sharing my six-month Ayahuasca update with you guys! I thought this series was over, but here we are officially on episode five. I highly recommend you guys listen to episodes 116, 120, 121, and 122 first for context. In episode 161 I share why I did Rythmia. In 120 and 121, I recap what I could remember at the time from ceremonies 1, 2, 3, and 4, and episode 122 outlines the lessons I learned and will be taking with me in my everyday life. Rhythmia was the most TRANSFORMATIONAL time for me, it was truly LIFE CHANGING. I am excited to share with you my six-month update.    I have been receiving so much great feedback from you guys around how I have encouraged you to book your tickets to Rythmia as well, so in this episode, I will be sharing my thoughts on if I would do Rythmia again and my six-month post-Costa Rica update. Lastly, I’ll be sharing everything that happened that I did not expect from the moment I left Costa Rica. I hope you find this episode INSPIRATIONAL!   If I have inspired you to go to Rhythmia, if you have learned anything from my Ayahuasca series, or you resonate with this episode or know someone who will find massive value from this series, please be sure to tag me @manifestationbabe on Instagram and share this episode with your community to spread the word! Also, be sure to leave a review on iTunes in order to receive a free manifestation hypnosis. Just screenshot it before submitting and email it to my team at hello@manifestationbabe.com and I will see you in the next episode.   In This Episode You Will Learn:    Things I did not expect to happen after Rythmia (6:35) The scariest change I experienced (15:24) How Ayahuasca has opened up my psychic abilities (22:00) How my vision affected my business (27:17) My biggest warning before attending Rythmia (36:25) Questions I Answer:    What terrified Brennan and I after Rythmia? (8:03) How long does Ayahuasca stay in your system and consciousness? (18:33) How my tolerance for things that do not serve me has changed? (23:02) How I have been tested in regard to the visions I saw during the ceremonies? (27:10) How does Ayahuasca work in regards to old habits? (30:25) Will I ever attend Rythmia again? (32:30) Links/Resources  (#122) What I Learned From Drinking Ayahuasca and How It Transformed My Life       (#121) So I Drank the Ayahuasca (Ceremony 3 & 4 Recap)       (#120) So I Drank the Ayahuasca & Here's What Happened (Ceremony 1 & 2 Recap)       (#116) Why I'm Going to Costa Rica to Drink a Hallucinogenic Brew (Ayahuasca) The Morning Manifesters Journal For Massive Momentum, Motivation & Magic Manifestationbabe.com/links Follow me on Instagram  Join our Manifestation Babe community!  Visit our website!

‘Plant medicine is going to explode in the next few years.’ In this special podcast, we’re joined by Mindvalley founder Vishen Lakhiani and globally celebrated ‘Chicken Soup for the Soul’ author Jack Canfield to explore Plant medicine. They share some fascinating stories about their Ayahuasca experiences. Get strapped in...it’s going to be an epic, if not bumpy, ride! So why is the famed plant medicine deemed as an illegal drug right now? And what can you expect to experience if you take the plunge? Listen out for: Vishen’s first Ayahuasca Experience and why it wasn’t remarkable. Vishen’s second Ayahuasca Experience & how the universe communicated with him... The 3 questions you can ask when you are in Ayahuasca.  The 7 day Ayahuasca retreat at Rhythmia where you can have a transformational experience. The Humorous Conversation between Jack and his Soul. Why is the famed plant medicine deemed as an illegal drug in some countries? And where can you have the experience yourself? Like this episode? Subscribe to our Podcast on iTunes and Spotify. Tag us @Mindvalley on Instagram or Twitter too! Mentions: Want to learn more about Altered States of Mind ? Join Vishen on this FREE masterclass where he shares tips on How to access Altered States of Mind for profound creativity and intuitive guidance - https://go.mindvalley.com/AlteredStates To purchase your top quality CBD oil, go to https://camillaorganics.com/

The Final part of our mini-series on psychedelics, I conclude the story of my experience at Rhythmia, Life Advancement center, share my lessons from my "trip"   Website: https://www.filthywellness.com/     Follow me on Instagram: https://www.instagram.com/gregxavier_/   Filthy Wellness Podcast On Instagram: https://www.instagram.com/filthywellnesspodcast/   Buy "How To Change Your Mind" on Amazon   Disclaimer: The podcast does not provide medical advice. The Filthy Wellness Podcast is for information purposes only. The medical and/or nutritional information contained within the podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition. Listening to the podcast constitutes acknowledgment and acceptance of these limitations and disclaimers.

Today's episode is so vibrant! Kehla had the opportunity to interview this incredible woman & Life Coach Zoey who shares her journey into living her dream life after leaving the corporate world. In the episode the ladies riff on a variety of topics regarding: taking the leap of faith in life into what you actually want to be doing, how Zoey started Youtube & became viral, minimalism, what it's like using psychedelics such as ayahuasca & shrooms for deep healing, creating quantum leaps, manifestation, attraction vs. creation & so much more The conversation in this episode is fun, authentic & of course juicy with personal experience/thoughts being shared! Enjoy!   Mentioned resources: Rhythmia - Spiritual Retreat Center Zoey's books on Amazon The Queen Mind Tribe - Zoey + Lauren's Facebook Group "Mind Power" - by John Kehoe "Reality of Truth" - Documentary The Landmark Forum - Personal Development course Episode #1 Imagination Creates Reality - Neville Goddard podcast episode   Follow Zoey on: Instagram Facebook YouTube The Lo & Zo show (podcast)   Join Kehla’s facebook group Follow Kehla on Instagram Check out Kehla's website   Please share these episodes, like, comment so that these powerful messages can get out into the world & help the people who need it most Thank you so much for tuning in!

This week’s Q&A is a doozy. You know, when I started doing these solo episodes, I really thought they’d be shorter than my interviews. But, as it turns out, I have a lot to say about this stuff! There’s just so much information out there — and misinformation — and I want to make sure you all get the best and most comprehensive answers I can provide. If you want to ask a question for a future episode, come join The Life Stylist Podcast Facebook Group. You can watch the next episode live, ask questions to both me and the group, and build a community of like-minded biohackers.  Plus, if I don’t get to your question on a future episode, one of our brilliant members will almost certainly help you out (and probably with an even better answer). The amount of knowledge and the enthusiasm of members is astonishing, and as you’ll learn in this episode, I have some big plans for the community in 2020.   00:12:00 — Michael asks: Any updates on the aftermath of your Rhythmia experience? Since this question was posted, I went back to Costa Rica for four more ayahuasca ceremonies, this time at Soltara. On February 18th, I’m dropping a two-part episode documenting the entire experience in a play-by-play gonzo reporting podcast series, just like the Rythmia episodes.  Then on February 21st, I’m posting a special bonus show where I do a deep dive comparison between the two Costa Rican ayahuasca centers.  I also recently participated in 3 different peyote ceremonies and recorded a podcast about that whole experience, which will be released this spring.   00:16:40 — That said, after Rhythmia, I would say the changes I feel are: I feel much less triggered emotionally Psychic wounds are healed; old memories have lost their ‘charge' Much less dependent on my spiritual practices to stay connected to god I’ve been microdosing ayahuasca before bed, which has helped me stay connected Looking forward to experimenting with some other plant medicines when it feels right Ayahuasca is not for everyone. It's a serious commitment and not something I would promote. It has to be something you are personally drawn to partake in. But for me, it was incredibly expanding, and something I foresee becoming a semi-regular part of my healing journey.   00:36:00 — Evan wants to know what you can do to improve air quality in your home due to living in LA. #1 Plants Here are some of the best for cleaning indoor air: Bamboo Palm Chinese Evergreen Gerbera Daisy Dragon Tree Pot Mum Peace Lily Spider Plant Mass Cane/Corn Plant #2 air filters Run a Living Air ozone generator in your home when you ARE NOT THERE, then open windows and air the house out when you return to give your house a deep clean, air-wise. Be careful — do not breathe ozone! I have two Austin Air Healthmate HEPA filters and a Dyson fan heater, which has a filter element. The Dyson sucks due to it having WiFi, but for right now I’m taking one for the team in order to be warm and filter the air in the living room, at least a little. Keep in mind that the air filter business is super shady and competitive, just like the mattress and sauna industries. There’s so much in-fighting and misinformation that it’s hard to know who to trust. Based on my research, here are some of the most effective filters on the market: Molekule AirOasis IQAir Dyson Pure Hot + Cool Pure Air Doctor (Dr. Roy)   00:57:45 — Karen comes to us with an important question: “When (not if) Facebook joins in on the great health purge and shuts this page down, what is an alternate place we can 'gather' for our discussions?” I am currently equally terrified and disgusted by the censorship of big tech giants like FB, Twitter, Apple, YouTube, Google, and even Instagram. They are shutting down free speech, especially from out-of-the-box thinkers and natural healing advocates like Kelly Brogan and anyone who dares question the safety of vaccines, etc. They picked Alex Jones as their first test case, and since nobody in alternative media stuck up for him, they are now going after anyone who opposes the mainstream narrative. They are completely totalitarian, fascistic, and absolutely engaged in illegal antitrust violations.  We can’t wait around for government intervention, so to answer your question, I am currently working behind the scenes to create my own platform, free of the Nazi-like censors on Facebook where we can all interact in an open dialog that is supportive of all people, regardless of beliefs. Who knows how long podcasts like mine will even be allowed on Apple Podcasts since Apple is one of the worst censorship offenders. I am not afraid, for every human has the god-given right to free speech and those of us who have the courage to challenge societal norms and risk being silenced will not only survive the storm but prosper in the end. Truth and love always prevail over deception and evil.   01:17:20 — Carlos asks: “It was suggested to me by my doctor to look into Riboflavin for my tension headaches

Here’s to living a life on purpose! In today’s pod, I had the absolute honor of interviewing a new yet dear friend of mine: Natalie Ledwell. Natalie is a risk-taker, non-conformist, rule breaker and maker who believes that nothing is impossible. She’s an authentic and internationally renowned motivational speaker, best selling author, law of attraction guru, and co-founder of Mind Movies. Her mission is to empower 10 million adults and kids all around the world to lives fulfilled with joy, happiness, and passion—the lives that they were destined to live. Natalie and I met on the plane home from Rhythmia and immediately connected. Since then, I spent New Year’s Eve with her and other close friends, as well as a whole afternoon in her home in Marina Del Rey. Throughout our conversation, Natalie puts it all on the line. She shares, in detail, her Ayahuasca journey and how it’s impacted her life. Specifically, she talks about her experience of healing her heart, learning what it truly means to surrender, and the lessons she brought back home with her. Without further ado, enjoy my yummy behind-the-scenes conversation with the remarkable soul, Natalie Ledwell. Some Questions I Ask: What did you see during your Ayahuasca experience? (7:58)What drew you to Ayahuasca? (18:24)What’s your journey been like since you’ve come back home? (35:06)What’s the ultimate intention behind Mind Movies? (39:20)In This Episode, You Will Learn: How Natalie’s heart was healed during her first Ayahuasca experience. (7:03)How Natalie learned how to truly surrender herself. (14:17)What tips Natalie has for surrendering during an Ayahuasca experience. (21:18)How merging back with her soul has influenced Natalie’s day-to-day life. (35:27)What Natalie’s morning rituals look like & how they influence her day. (47:37)Connect with Natalie Ledwell: WebsiteFacebookTwitterYouTubeResources: Mastery Momentum MastermindMind MoviesThe Inspiration Show PodcastPersonal Growth Studies See acast.com/privacy for privacy and opt-out information.

Ritu fills in Ken about her surgery, Ken tries to talk her out of her upcoming Costa Rica trip, and they discuss how they're both feeling about comedy.

After an unbelievable spiritual awakening at Rhythmia in Costa Rica, I am officially back to share my entire Ayahuasca experience with you here on the Manifestation Babe podcast! I found myself struggling to put the pieces together before recording this episode because there simply is no way to truly describe the transformative journey I went on.    In this episode, I cover my overall experience at Rhythmia, what was included, how I felt in the facility, and my experience taking Ayahuasca in the first two ceremonies. These episodes will be recorded in a series, so the next episode you can expect is a recap of the ceremonies from day 3 and 4. I will end the series with what I learned and took back home with me from this beautiful, sacred experience.    I hope you enjoy this episode and keep an open mind as I share with you the most life changing journey I’ve ever been on.    P.s 2020 is the year of the visionary and we’re letting go of anything and everything that did not serve us, to show up in the new year with massive momentum! We are officially jumping into a new decade and I want to invite you to join me in creating the BEST year of your life. Join me in my 3-day annual boot camp Epically Aligned, and learn to fully let go of all your disempowering beliefs, and enter into 2020 UNSTOPPABLE! If you want to predict your year, you have to create it!   Click here to create the best year of your life in Epically Aligned 2020 Bootcamp!  In This Episode You’ll Learn    Why I didn’t attend Rhythmia as an “influencer” (10:30) 3 magical intentions at Rhythmia (29:16) The Big 4 at Rhythmia (33:54) Ceremony #1 - Full Recap (44:20) Ceremony #2 - Full Recap (81:01) Questions I Answer:    What was my overall experience at Rhythmia? (15:30) What is the Labrinth at Rhythmia? (26:35)  What kind of journeys can you have on Ayahuasca? (36:20) Links/Resources    Join Epically Aligned 2020 Bootcamp   The Medicine Documentary   Follow me on Instagram    Join our Manifestation Babe community!    Visit our website!   Manifestationbabe.com/links  

Have you ever REALLY faced your fears? A few days ago, I returned home from my first ever experience at Rythmia Life Advancement Center in Costa Rica, where I stepped into a portal into the world of healing and spirituality—through Ayahuasca. For me, this experience was incredibly eye-opening; for the first time, I really faced my own demons, yet I also had the most epic, transformative, and healing week of my life in Costa Rica. I’m so excited to share it with you this week. In this episode, Dr. Jeff McNairy, the co-founder of Rythmia, and I discuss the science, art, and experiences that come with this medicinal experience. He specifically emphasizes that only real healing can come from within. Are you ready to face yourself? Some Questions I Ask: Tell me about your background. (6:29)How did you meet your co-founder and co-partner at Rythmia? (8:49)What causes a soul to split? (20:42)How did Rhythmia come to exist? (23:23)For those who are afraid of the Ayahuasca experience, what would you offer them? (37:07)Who is Ayahuasca for? (41:52)What’s the distinction between light workers and light warriors? (57:23)In This Episode, You Will Learn: Why Dr. Jeff was drawn to working with a patient, even though it seemed like he wasn’t getting any better. (11:28)How Ayahuasca changed Jerry’s life. (13:46)What it looks like to split from your soul. (17:25)How animals function as vehicles for us to connect with the spirit world. (22:22)About my experience with Ayahuasca. (33:41)Some examples of extraordinary successes from Ayahuasca. (47:45)What an awakened soul looks like. (1:00:24)Connect with Dr. Jeff: WebsiteRythmiaYouTube: Rythmia Life Advancement Center See acast.com/privacy for privacy and opt-out information.

"I'm not a thought leader, I'm not woke, I'm a guy that's a cheerleader for a plant." I'm so happy to introduce you to Gerry Powell, today's guest on NION Radio. 10 years ago, Gerry had just sold his company for $94 million dollars, had 5 houses, 20 plus cars, and 2 planes. He had achieved the American dream but was hooked on Demerol, was an alcoholic and was suicidal. Not even the top addiction rehab in the world could free him from his pain. But when a friend introduced him to an African plant, in one night he was healed from a lifetime of suffering. Today, Gerry is happy and free, and driven by the ease of awakening through plant medicine versus conventional routes, he has made it his life’s mission to show others there can be a shortcut to happiness. Being the founder and organizer of the Rhythmia event, I got to spend a lot of time around Gerry Powell during my time there, and he has given me so much in my own journey with my life and spirituality through plant medicine. Listen in to learn how Gerry began working with plant medicine, what Rhythmia has done for him and others, and how he uses data to improve the event. You can Subscribe and Listen to the Podcast on Apple Podcasts. And please leave me a Rating and Review! "Anytime you have a date with divinity, you are changed." Some things we learn in this podcast: How Gerry went from successful but depressed to a fully changed person through plant medicine [5:52] Why Gerry doesn't consider himself a thought leader [12:19] What inspired the development of Rhythmia [14:55] What our experiences with plant medicine can teach us about our world [17:41] Why Gerry doesn't feel bad about not leaving Rhythmia for months at a time [21:36] The feeling of being merged and how it changes everything you experience in your life [29:16] Why having a near death experience often changes people in the same way that plant medicine does [36:27] Why some people are okay with doing it once, while others come back again and again [39:07] What Gerry means by everybody getting their "miracle" [44:23] How the data that Gerry is collecting is being used to create a better experience for every Rhythmia event [48:46] How Rhythmia's team is maintained to keep their ceremony as good as it can be [52:17] Links Mentioned: How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence Sh*t The Moon Said: The Miraculous and Mystical Journey of Gerard Armond Powell Dying To Be Me: My Journey from Cancer, to Near Death, to True Healing Connect with Gerry Powell on Rhythmia's website | Facebook | YouTube | Instagram

"It's like if you got shot by a bullet and it got lodged in your body. Well you're not just going to leave it in there. You're going to want to excavate it." Have you ever felt totally trapped by how you react and sometimes overreact to situations? Like you're not in control and by the time you know what's happening, the damage has been done? This kind of behavior is often caused by deeply rooted trauma that can take years of therapy to overcome. But what if there was an easier way? A backdoor into your subconscious where you can work on taking care of that trauma? Today's episode of NION Radio is all about my journey with plant medicine and the power I see in it as a tool for growth, both personally and creatively. I go over my recent experience at Rhythmia in Costa Rica, the different medicines and their effects, and how creatives can benefit from these experiences. You can Subscribe and Listen to the Podcast on Apple Podcasts. And please leave me a Rating and Review! "Ayahuasca is a big tool for clearing those subconscious traumas." Some things we learn in this podcast: Nick's first experimentation with plant medicine and how that changed his outlook on life [1:16] What Nick experienced at Rhythmia in Costa Rica [2:40] How plant medicine can help you dig down deep into your subconscious and heal wounds from the past [5:17] How Ayahuasca works and how it works differently in different people [7:38] What Nick learned about himself and his past [11:32] Why clearing out your negative energies increases your creative flow [13:46] The understated importance of our gut [14:49] Links Mentioned: Rhythmia A New Earth: Awakening to Your Life's Purpose Ziva Meditation with Emily Fletcher Becoming Supernatural: How Common People Are Doing the Uncommon

Cami Petyn is a full-time Youtuber (Supreme Banana) and author of her first book Silence, a collection of her poetry and photography. She has been making Youtube videos for over 5 years, discussing her life and health journey. She is a mental health advocate, vegan, and lover of all things self-help, psychology, and spirituality.  We jump into talking about healing different traumas through a wide range of modalities, including therapy, fasting, kundalini yoga, meditation, psychedelics, and gratitude. Cami has recovered from an eating disorder in the past and opens up about intuitive versus restrictive eating as a vegan, plus her healthy relationship with food now.    We also talk about:  Cold therapy and cold showers Ayahuasca at Rhythmia in Costa Rica Overcoming anxiety and depression Choosing the right food for you Resources: Supreme Banana Youtube channel Cami Petyn Instagram @cami.petyn  Silence book by Cami Petyn   For more Biohacking with Brittany: Instagram @biohackingbrittany Connect on Facebook Subscribe to my newsletter through www.biohackingbrittany.com  Download my free Cycle-Syncing one-pager 

Get more podcast content, support Third Eye Drops and receive exclusive rewards by becoming a Patreon patron What's this?! Two mind melds in two days?! Sort of... Regardless of the nomenclature, I had a tremendous time hosting this conversation at WITMA featuring the following lovely humans --  Ramin Nazer - Comedian, artist and podcaster Colin Frangicetto - Artist and musician Zach Leary - Host of It's All Happening and the MAPS Podcast Brandee Lynn - Partner in Rhythmia (an amazing ayahuasca retreat and resort) Tricia Eastman - Psychedelic facilitator  For a video version of this panel, stay tuned to THIRDEYEDROPS.com Leave us some love on iTunes by clicking 5 starts and the subscribe button!

At this point in my Rythmia journey, I’ve already received a tremendous gift – I found my true purpose – but we’re still not done yet. Because we have two more incredible healers to meet in this episode: R. Christian Minson, the resident Director of the Breathwork Program at Rythmia Life Advancement Center, and Dr. Jeff McNairy, the Chief Medical Officer at Rythmia. Christian practices Transformational Breath, a practice that harnesses the power of your own innate healing capacity through cutting edge breathing techniques that access deeper amounts of life force energy, helping you to connect with yourself emotionally, physically, and spiritually. With Christian as your guide, the breathing brings you on insightful journeys that open you up to life changing events and shifts in consciousness. ​The results are meditative states of deep peace, energized enthusiasm for life, and an opening to the mystical realms of consciousness. It’s hard to believe that something so transformational can come from breath until you experience it, but it’s impossible to forget once you do. Christian was originally called to be a healer because he experienced the power of breathwork first hand – and if you listened to part one of my Rythmia journey, you can probably tell that this is a common theme here at Rythmia; the healed become the healers. And this is, at its essence, what Rythmia offers visitors: the opportunity to discover the light worker or light warrior essence within. Because when your light shines a bit brighter, you’re able to go out in the world and be of greater service. But this probably wouldn’t be possible or safe if it weren’t for Jeff McNairy, who has been working in the healthcare field for 25 years. He’s seen, over and over again, people struggling to heal because the current Western system of healthcare is simply deficient. It is more concerned with managing symptoms and prescribing “medicine” than healing. However, through working with some of the most intense patient populations – including those who struggle with addiction and trauma, like Rythmia co-founder Gerard Powell – he has seen that the only real healing can come from within; you have to find the root cause of your unhappiness, health concern, and discontent, then resolve it. And in working with Gerry and everyone else who has visited Rythmia since it opened, Jeff has seen that one plant medicine session conducted in a safe, clinically appropriate environment can be as effective as 10 years of psychotherapy. Like breathwork, it’s hard to believe that plant medicines can be so transformational – and then you experience it under the right conditions. It’s ancient modalities meeting modern psychology, all in the jungles of Costa Rica, and I invite you to come join me for the rest of this wild, profound, and emotional ride.   Topics Discussed With Christian: What breathwork is & how it can help you in ways that yoga can’t Why Christian became a monk for a decade (and then made the transition back to being a worldly person) How the healers at Rythmia help visitors find the light warrior essence within them What separates Transformational Breath from the hundreds of other breathwork practices out there Rebirthing through breath Plant medicine and breathwork both open up the door to consciousness – but breathwork opens the door and gently beckons you in while plant medicine grabs you and shoves you through the doorway The benefits of integrating a natural habitat into your spiritual experiences How breathwork works with plant medicine to evolve your experience & help you claim it as your own   Topics Discussed With Jeff: How the staff at Rythmia ensures that the plant medicine experience is safe for everyone involved A lot of what we call mental illness is just people in pain without any way to process that pain Using a drug to get off drugs (AKA why plant medicine is so effective for treating addiction) How it it possible that I had a psychedelic experience and, now, feel even more committed to being sober? (Trust me, that would never happen after a bump of coke...) When Jeff first met Gerry, who was then a very different person than the person you met in the last episode, and their transformational entré into the world of plant medicines The difference between iboga and ayahuasca, experientially and physically A common thread of trauma that has rippled throughout my life, especially my romantic life How the plant medicine helps you work through your own trauma and start the healing process We can’t connect with other people until we get connected with ourselves Why Rythmia accepts people who are shunned or devalued in many Western medical facilities due to their particular mental illness What science is starting to learn about the pineal gland & DMT How a dog helped me find God The three intentions that will help you find everything you’re looking for at Rhythmia   More about this episode. Connect with Luke on social media to learn how to take your lifestyle to the next level, plus catch exclusive live interviews & events: INSTAGRAM - @lukestorey // https://www.instagram.com/lukestorey/ FACEBOOK - https://www.facebook.com/MrLukeStorey/ TWITTER - @MrLukeStorey // https://twitter.com/MRLUKESTOREY YOUTUBE - https://www.youtube.com/c/LukeStorey   THIS SHOW IS BROUGHT TO YOU BY: ORGANIFI. I talk about the Organifi green juice a lot because it’s delicious and I eat it every day, but did you know that they also make a red juice? This red juice powder is packed with antioxidants, immune-boosting herbs, and adaptogens like reishi and cordyceps mushrooms (which are really hard to make taste good – I have no idea how they did this). It’s super quick and easy nutrition on-the-go. Save 20% using code “LIFESTYLIST” at http://www.organifi.com/luke. AND... ALITURA NATURALS. Your skin is the largest organ and it needs to be treated like another mouth. If you're as careful about what you put on your skin as you are about feeding your body, then you’ve got to check out my good friend and previous podcast guest’s skincare line, Alitura Naturals. Alitura was created out of desperation after it’s founder, model, and actor, Andy Hnilo, found his face unrecognizable after getting hit and run over by two cars. Alitura, latin for ‘feeding and nourishing,’ was created out if a small studio apartment, purely out of necessity to heal Andy’s scarring and abrasions. Carefully sourced with research proven ingredients containing natural, organic, nutrient-rich ingredients that feed and nourish your skin, so you can look as vibrant as you feel. And as a special gift for my listeners, use code “lifestylist” for 20% off and FREE SHIPPING in the US on your order at http://alituranaturals.com. AND... ONDA WELLNESS. If you’re a discerning health enthusiast like myself, you’ve probably sat and scratched your head at the health food store trying to figure out which CBD product you should buy. They all make big claims, they all say they’re the best, but what actually works? Well, I just found a brand that I’m super stoked about, and I want to share it with you: ONDA offers a patented and truly full-spectrum line of products that aren’t dependent on the use of alcohol, CO2, or other solvents for extraction – and this is important because when you’re getting the medicine out of the plant, you don’t want to add poisons to it! You can try it for yourself and get 15% off using code LUKE15 at www.ondawellness.com. HELP SUPPORT THIS SHOW! Starting and growing a podcast requires a ton of time, energy, and money. Do you appreciate this information, and want to support my mission to deliver as much life enhancing information as possible to as many people as possible? The easiest, and most effective way you can help is to do this: Go to Lukestorey.com/support and donate towards show production costs Subscribe to the show by clicking “subscribe” in iTunes Write us a review in iTunes Share this show with one friend right now You’d be amazed how much these four simple steps do to help us grow! Here’s the magic link for reviews in iTunes. Or, if you want to get there yourself, you can follow these instructions. Thank you from the bottom of my heart for listening and joining me on this journey we call life

Cami Nicole Petyn — otherwise known as Supreme Banana — is a Youtuber, social media personality, and all-round entertaining human being who has been putting her life, messages, and content on the digital landscape for around four years now. Among also being a published author, vegan advocate, and seeker of philosophy, Cami has an interest in the biohacking mental and spiritual benefits of psychedelic compounds, which is one of the main topic we're discussing today. Not long ago, Cami experienced ayahuasca for the first time, attending a 4-day retreat in Costa Rica to sit with this plant medicine teacher. Although I haven't personally yet experienced ayahuasca, I was drawn to interview Cami for three reasons: first, I've experienced DMT (similar to ayahuasca, but smoked), I've had a desire to experiment with ayahuasca for quite some time, and I'm always extremely interested in hearing stories of people's first time with these intense psychedelic compounds. In this episode, we discuss how to escape the cycle of social media controlling your thoughts and emotions, what is life for an influencer and how unglamorous it can actually be sometimes, information on what ayahuasca is like for a first-time users, how Cami dealt with fours straight days of doing ayahuasca in Costa Rica, set and setting, the difference between a great ayahuasca experience and a not-so-great one, what ego death feels like, Cami's description of "Peach Air" and what that means in terms of an ayahuasca trip, how to know you're ready to experience a psychedelic experience like this, and so much more. One thing that's extremely important to consider when seeking out ayahuasca, is finding a location, setting, and shaman that will correctly guide you through the experience. Cami and other people I know speak extremely highly of Rhythmia, who Cami also mentions in this episode, which I will link to below. Get her videos and other content into your eyeballs via the links below.   CAMI'S YOUTUBE: Supreme Banana CAMI'S INSTAGRAM: @mssupremebanana CAMI'S TWITTER: @mssupremebanana CAMI'S BOOK: https://amzn.to/2PdCaAa    A NEW EARTH BOOK: https://amzn.to/2KMnXf1  YOU ARE A BADASS BOOK: https://amzn.to/2XhLw0u  RHYTHMIA: https://www.rythmia.com/    STUDY - KIDS WANTING TO BE INFLUENCERS: https://bit.ly/2Gnxi7h  STUDY - SOCIAL MEDIA & THE BRAIN: https://bit.ly/2N8kurK    CONNECT Connect with Leon The Alchemist online for more intensive biohacking, longevity, and performance advice daily, with exclusive content you won't find anywhere else: INSTAGRAM: @LeonTheAlchemist | https://www.instagram.com/leonthealchemist  TWITTER: @AlchemistLeon | https://twitter.com/alchemistleon LINKTREE: https://linktr.ee/leonthealchemist WEBSITE: http://bioalchemy.co COURSE: http://bio.ax/   LEARN Want to take your biohacking skills to the next level? Wake up feeling better each and every day? Or as Dr Aubrey De Grey has suggested, see if you can implement some of the longevity biohacks that may see you living to 1,000 years or more with advancements in technology? Then my intensive biohacking course The Alchemist's Guide to Biohacking (http://bio.ax/) is something you should consider becoming a student of. Use the code "HALF" during the first month of this podcast being launched to get 50% off lifetime access, with all future updates. Check it out at: http://bio.ax/    SUPPORT I spend a ton of time putting together this podcast, and would love your support. Whether as simple as reviewing this podcast, to checking out the products I recommend, or even becoming a student of my intensive biohacking course "The Alchemist's Guide To Biohacking", I appreciate every human who supports me, however large or small the action. ITUNES: https://apple.co/2GQnXH2  SUB ON GOOGLE: https://bit.ly/2SbvJ05  BIOHACKING COURSE: http://bio.ax/

What inspires you to work out and eat right? We know there are long-term health benefits to exercise and good nutrition, but sometimes that’s just not enough to keep us engaged. What if you knew you could use your strength, your proprioception and even the social skills you are developing through your wellness practice to embark on epic adventures? What if good health allowed you to expand what’s possible—and live a totally badass life? Adam and Vanessa Lambert are the cocreators of Bee the Wellness, an innovative personal coaching company based in California. The pair has 10 years of experience in ancestral nutrition and training, and they are passionate about educating and empowering clients on their journeys to optimal health. Bee the Wellness offers one-on-one and group coaching as well as transformative retreats in Machu Picchu, New Zealand, Montana, Costa Rica and Africa. Today, Adam and Vanessa join us to share their take on living a badass life. They discuss how Bee the Wellness leverages adventure to keep people engaged and expand what is possible for their tribe. Vanessa and Adam describe the upcoming Rhythmia Retreat in Costa Rica, sharing their own profound personal experiences with plant-based medicine. They also discuss the epic adventures offered through Bee the Wellness, sharing the details of the Montana Retreat at Glacier National Park. Listen in for insight on incorporating movement, mindset and mindfulness into your life and learn how to become a part of the inclusive Bee the Wellness community! Topics Covered [2:07] Vanessa’s health and fitness journey Shy kid, put in sports to build confidence Turn to physicality when face challenges Early days of CrossFit, ancestral movement [6:47] Adam’s health and fitness journey Promoted to company officer of firefighters Introduced S&C to improve squad abilities Work with Robb Wolf (support first responders) [10:16] The power of adventure in living a badass life Source of motivation to keep people engaged ‘Expand what’s possible in experience of life’ [12:29] What to expect at Rhythmia in Costa Rica Plant-based medicine retreat (psychedelics) Altered state for healing, spiritual development [15:43] Adam’s experience with ayahuasca Objective, alternate view of internal dialogue Allows for fundamental shifts in perception [19:21] How Rhythmia changed Vanessa’s life for the better Realized coffee creating stress response Able to easily, gently step away [22:57] The legal issues around plant-based medicine Fully legal in Costa Rica Licensing process = well-monitored, safer [23:52] Vanessa & Adam’s Montana Epic Adventure Retreat Held on ranch near Glacier National Park Hiking, horseback riding + custom coaching Movement, mindset and mindfulness habits [27:17] The breathing techniques Vanessa & Adam teach Box Breathing, counting breaths PRI and Wim Hof methods [28:44] How Vanessa & Adam incorporate mindfulness Lead guided meditations ‘Infuse experience with moments of mindfulness’ [31:29] Vanessa & Adams focus on building a tribe Inclusivity baked in as priority of company Community pays forward, welcome newbies [36:01] The benefit of Vanessa’s Authentic Self Program Coaching to prepare for plant-medicine work Additional support before and after Rhythmia Learn More About Adam & Vanessa Lambert Bee the Wellness Bee the Wellness Podcast Bee the Wellness Retreats & Adventures Resources Robb Wolf Mark Sisson Core Performance by Mark Verstegen and Pete Williams Ayahuasca Foundation Postural Restoration Institute Wim Hof Method Vanessa’s Authentic Self Program Wellness Force Radio EP185 Personal Growth & Plant Medicine Bee the Wellness EP153 Rhythmia Wrap-Up Bee the Wellness EP141 Rhythmia Founder Gerard Powell

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

worker We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and cr...

We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and creating my ...

We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and creating my ...

We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and creating my ...

We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and creating my ...

We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and creating my ...

We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life. So, come on and watch the video below:  For my Guided Meditation MP3 on raising your vibrational set-point Click Below… http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6 Follow me on Instagram aaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review here https://www.youtube.com/watch?v=6sV-bD5242k (Click here to watch on YouTube) I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months. Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November. We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos. She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and creating my ...

We are going to show you a full moon ceremony for integrating your shadow self. This is a completely transformative time on the planet right now with the full moon that's coming up and doing this ceremony and what we share with you will change your life.So, come on and watch the video below: For my Guided Meditation MP3 on raising your vibrational set-point Click Below…http://bit.ly/2DjkxZu  To experience THE SHIFT, click here http://bit.ly/2ImCGZ6Follow me on Instagramaaron_doughty44 Subscribe to the Show on itunes herecan you leave a review for the podcast? I would soo appreciate it You can leave a review herehttps://www.youtube.com/watch?v=6sV-bD5242k(Click here to watch on YouTube)I'm here with Leeor Alexandra. Keep your vibrations way, way, way, way up, and today what we're going to be sharing with you is exactly how you can integrate your shadow using the power of the moon or we're going to be sharing our own experience with this. This is something I think is so transformative. If you are reading this blog right now, then the full moon is coming up and we want to share with you a way that you can get a similar result that can transform our lives from the comfort of your own home. Using the powerful process, we share, but we want to do today is we want to share with you some of the profound insights that we've had over the last one, like two months.Three months, two or three months since we went to Rhythmia and Costa Rica and just to share with you how you can go through and integrate what is called your shadows. This can be like a little shadow training where we're going to share with you how we transformed our integrated, what's called our shadow to do shadow work, which then has transformed our whole entire lives. And I know, I know looking at you and seeing you in the last two or three months, you're a totally different person and I'm sure you say the same thing about me these last two or three months. I'm a totally different person because we went to Costa Rica and this isn't about Costa Rica, but we're going to share a little bit about our experience at Costa Rica. And we both went to Costa Rica and it was the second week of November.We were there for a whole week and we were doing something that's called plant medicine was. I know it sounds kind of weird. I know when I first went I was like, I'm not doing this, like I'm just going to go for the vacation, you know, and I was kind of reluctant to do it, but once I did, it's where you go really deep in your subconscious mind and you understand things that were holding you back or things that were kind of causing a certain pattern in your life that you just weren't aware of. And what I thought we would do is share a little bit about those things that we experienced and how that transformed our own lives. I know that when you went, you had a profound experience. We've talked a little bit about that, about, and if you guys don't know, by the way, this is Leeor Alexandra, she makes amazing YouTube videos.She's very well known on YouTube and for what she does and how much she puts out amazing content on Law of Attraction spirituality, very similar to my content. If you haven't followed her already then definitely do that anyways. At Rhythmia, after the plant medicine, which I really wasn't sure if I was even going to do the first night, was very intense because that's when I had the deepest shadow work and the shadow work was what was happening was that the plant medicine was showing me parts of myself, things I've forgotten are put into the, into the depths of my subconscious mind in order to function normally because I couldn't heal from it. I didn't have the tools to heal from what I experienced in my childhood and growing up teenage years, a lot of things, a lot of traumatizing Korean things that I never realized were impacting my behavior. And they were affecting the way that it was manifesting and creating my reality because I didn't realize how deep my issues w...

Dr Paul Wang:                   Welcome to the monthly podcast, On the Beat, for Circulation: Arrhythmia, and Electrophysiology. I'm Dr Paul Wang, Editor-in-Chief, with some of the key highlights from this month's issue.                                                 Koji Miyamoto and associates conducted the AD-Balloon Study, which investigates the ideal number of free cycles during second-generation cryoballoon pulmonary vein isolation. In a prospective, multicenter, randomized clinical trial, the authors compared in 110 patients the addition of a three minute freeze after pulmonary vein isolation had been achieved to pulmonary vein isolation alone. Delayed-enhancement magnetic resonance imaging was also performed one to two months after the pulmonary vein isolation to assess the ablation lesions. The freedom from atrial arrhythmias at one year was similar. Log rank test, P equals 0.78 in the two groups, 87.3% in the extra three-minute freeze group, and 89.1% in the pulmonary vein isolation group. There was no significant difference in the frequency of gaps on the pulmonary vein isolation lines in the delayed-enhancement magnetic resonance imaging. The authors conclude that an insurance freeze after achieving pulmonary vein isolation may be unnecessary and time consuming.                                                 In our next study, Robert Sheldon and associates examined the genetic basis of vasovagal syncope. They studied 160 subjects in 9 kindreds comprising 82 fainters and 78 controls. Common genetic variants were genotype for 12 genes for vascular signaling, potassium channels, the serotonin 5-HT1A receptor, the serotonin transporter and catecholamine-O-methyltransferase or COMT. They found that in 9 of 12 variants, there was no significant association between genotype and phenotype. However, the serotonin 5-HT1A receptor, HTR1-A G alleles were associated with syncope in males but not in females. P equals 0.005. The men with serotonin 5-HT1 receptor C alleles had a 9% likelihood of syncope while Gg males had a 77% likelihood of syncope. The SL6A4 promoter L alleles were associated with decreased syncope in males but increase in females. P equals 0.059. The Ll males had a 25% syncope likelihood and Ss males had a 47% syncope likelihood. The COMT A alleles were associated with decreased syncope in males but increased in females. P equals 0.017. The Gg males had a 50% syncope likelihood and A males had a 15% syncope likelihood. The Gg females had 52% syncope likelihood and the Aa females had a 73% syncope likelihood. The authors concluded that there is a sex-dependent effect of alleles of serotonin signaling in vasovagal syncope, supporting the serotonin hypothesis of the physiology of vasovagal syncope.                                                 In the next study, Michael Barkagan and associates sought to examine whether the standard criteria for mitral line block with endocardial and epicardial activation mapping may not distinguish from slow conduction or conduction via epicardial bridging connections. In 56 patients, the authors creates a posterior mitral line using radiofrequency ablation. Mitral block determined by pacing with conduction block defined as trans-isthmus time of 100 milliseconds or greater in reversal of coronary sinus activation during pacing from the left atrial appendage was achieved in 51 out of 56 or 91% of patients. In 11 of 51 or 22% of patients, high-resolution activation mapping, using Rhythmia, of the endocardium and epicardium via the coronary sinus demonstrated residual endocardial in 27% or residual epicardial in 73% connections. Epicardial bridging connections were distant from the line, 2.4 plus or minus 1.6 centimeters, inserting laterally at the proximal-mid coronary sinus and septally at the left atrial ridge. Patients with residual conduction were prone to complex circuits involving the epicardium in 7 of 11 patients. Mitral line block was achieved in 75% by targeting these insertion sites. The trans-isthmus time had limited predictive value for distinguishing block from pseudoblock. The authors concluded the connections are a frequent cause of complex circuits, and their insertion sites can be targeted for ablation.                                                 In our next paper, Santiago Rivera and associates examined the causes of QRS variability in Papillary muscle arrhythmias usually attributed to anisotropy. In 33 patients with papillary muscle arrhythmias prospectively undergoing cardiac resonance imaging, papillary muscle connections away from the papillary muscle base were identified. Arrhythmogenic papillary muscles, N equals 35, exhibited a higher number of papillary muscle connections, 72 versus 18, P equals 0.01. Patients with inconsistent QRS precordial transition and inconsistent QRS access exhibited a 100% prevalence of papillary muscle connections. Those with consistent precordial transition and consistent QRS access showed 40% and 26% prevalence of papillary muscle connections respectively. Inconsistent QRS precordial transition and inconsistent QRS access predicted the presence of papillary muscle connections with 59% or 28% sensitivity and 100% specificity respectively. Those papillary muscles exhibiting clinical recurrence after ablation presented a higher prevalence of papillary muscle connections, 91% versus 60%, P=0.04.                                                 In our next paper, Jason Coult and associates examined the quantitative measures of the electrocardiogram waveform during ventricular fibrillation to assess myocardial physiology and predict cardiac arrest outcomes. They collected five second ventricular fibrillation ECG segments with and without chest compressions prior to 2,755 defibrillation shocks from 1,151 out of hospital cardiac arrest patients. 24 individual measures and 3 combination measures were optimized to predict functionally intact survival using 460 training cases. Measures predicted functionally intact survival in 691 independent test cases with an area under the receiver operating curve (AUC) ranging from 0.56 to 0.75 without chest compressions and 0.53 to 0.75 with compressions, P less than 0.001. Of all measures evaluated, the support vector machine model ranked highest both without chest compressions, AUC equals 0.75, and with compressions, AUC equals 0.75. The authors concluded the waveform measures predict functionally intact survival when calculated during chest compressions, but prognostic performance is generally reduced compared to analysis without compressions. Support vector machine models exhibited similar performance with and without compressions while also achieving the highest area under the curve.                                                 In our last paper, Hailey Jansen, Martin Mackasey and associates examined the effective natriuretic peptides in the specific natriuretic peptide receptor NPR-C on angiotensin II-mediated atrial fibrillation. The authors examined wild-type and NPR-C knockout mice to investigate the effects of angiotensin II administered three milligrams per kilo per day for three weeks on atrial fibrillation susceptibility and atrial function. In wild-type mice, angiotensin II increased susceptibility to atrial fibrillation and associated with a prolonged P wave duration, increased atrial refractory period, and slowed atrial conduction. These effects were exacerbated in angiotensin II-treated NPR-C knockout mice. Angiotensin II prolonged action potential duration and reduced action potential upstroke velocity. Angiotensin II also increased fibrosis in the atria in wild-type mice while angiotensin II-treated NPR-C knockout mice exhibited substantially higher atrial fibrosis. Co-treating wild-type mice with angiotensin II and the NPR-C agonist cANF, those dependently reduced atrial fibrillation inducibility by preventing some of the angiotensin II-induced changes in atrial myocyte electrophysiology and preventing atrial fibrosis. The authors suggested that the NPR-C receptor may represent a new target for the prevention of angiotensin II-induced atrial fibrillation via protective effects on atrial, electrical and structural remodeling.                                                 That's it for this month! We hope that you'll find the journal to be the go-to place for everyone interested in the field. See you next time! This program is copyright American Heart Association 2019.

My friend, we’ve arrived at the end of yet another incredible year of 250+ podcast episodes discovering the physical and emotional intelligence to live life well.   ---> Join the Wellness Warrior VIP Club: get exclusive discounts on new wellness tools, be first in line for new podcasts, get access to invite-only events, and so much more.** ---> Get The Morning 21: A powerful (and free) system designed to give you more energy, let go of old weight, and live life well. JOIN THE FACEBOOK GROUP | *REVIEW THIS PODCA   **Enter To Win A Free 90 Day Supply of Organifi! To enter to win a *Free 90 Day Supply of Organifi: all you have to do is leave a 5 star review right here for the podcast on iTunes right from your phone or computer during the contest period (12/28-1/1) and you'll be automatically entered to win. **Entrants must leave a 5 star podcast review for Wellness Force Radio on iTunes by 1/1/2019 at 11:59pm EST Here's how you can click to leave a review from your iPhone, easily right now. Just follow the directions in the video at wellnessforce.com/251. That will take you right to the review screen on your iPhone and after you hit “send” that’s it, you’re entered! Just a quick head’s up, after you hit send, your review won’t show on iTunes for 24 hours.  Any questions on how to enter from your computer? A quick 30-second video will show you how below at wellnessforce.com/251 **(1) winner will be chosen by a random computer and your iTunes username will be announced on January 1st right from the Wellness Force Facebook page, so make sure you like our page and turn on notifications to claim your prize on January 1st. Free Giveaway: Win A Free 90 Day Supply of Organifi!  Here's To Another Incredible Year If you’ve been listening to Wellness Force for a while, or if you’ve been with us since the beginning, you know by now that great things tend to take us time, effort, and the hardest one of them all - trusting the process - especially when it comes to our wellness. For episode 251, we spotlight 8 of our favorite moments over 2018, to pull the gems of wisdom, moments of laughter, and the real-life action steps that I've learned to both trust and believe in. I want to share my truth: This entrepreneurial and podcast path has not been 100% rainbows. Even since early childhood, I have known, deep down, that I march to the beat of a different drummer. Maybe you feel that too, and that’s why you’re here. I’ve faced inner and outer demons I wouldn’t wish on anyone, and since I began to wake up in 2012, I’ve done some deep work to let go of old stories about genetics, beliefs, and the people and things that don't serve my wellness. But yet as hard as this has been, I’ve also learned that when you operate from a place of love and service to others, and if you really want something, all the universe conspires in helping you to achieve it. This podcast has been my life since 2015, and today, I get to give thanks to YOU! 2018's Top 8 Wellness Force Dr. Cortney Warren In episode 177, Clinical Psychologist, Researcher, TEDx Talk Speaker, and Author of Lies We Tell Ourselves: The Psychology of Self-Deception, Dr. Cortney Warren, dives into how you can transform your life while experiencing trauma, misery, and self-doubt. Furthermore, Dr. Warren shares the importance of taking a deep look at yourself, being honest, and accepting who you are without judgment. Only when you do that, can you develop the strength to change your life despite hesitation or fear.   Dr. Michael Gervais What does it mean to be human and perform to your optimal level? How is authenticity the most powerful tool that will allow you to be truly you? Our next guest is, licensed psychologist, Co-founder of Compete to Create, and Podcast Host of Finding Mastery, Dr. Michael Gervais, who will teach you how to unlock the center of your mastery through self-expression, inner work, and gratitude. In episode 201, you will find out why practicing being in the present moment will lead to healthy habits, behavior change, and positive new traits.   Peter Sage As you listen to episode 245 with International Speaker, Entrepreneur, and Author of The Inside Track, Peter Sage, will help you discover the real difference between pursuing your passion and following your potential. As Peter has taught various entrepreneurs of all different backgrounds, the different levels of consciousness and the art of surrender will help you re-contextualize your negative thoughts when outer life doesn't fit your inner world. Discover how to go from the lowest level of vibration of victimhood to your best self through letting go, coming from a place of power, and putting your trust into something greater than yourself.    Paul Chek - Part 1 What actions can you do to become a better universal citizen of today's modern world? In Part 1 of 3 in episode 226, Author of How to Eat, Move and Be Healthy, Creator of the PPS Success Mastery Program, Founder of the C.H.E.K. Institute, Paul Chek, reveals the vital importance to honoring your mind, body, and spirit through The 4 Doctors - Doctor Happiness, Doctor Diet, Doctor Quiet, and Doctor Movement. Taking a deep look at modern society, learn how you can begin to properly feed your physical body, emotions, and mind through organic nutrition, real connection, and new ways of thinking.   Gerry Powell In episode 185, entrepreneur, Founder of Rythmia Life Advancement Center and Author of  Sh*t The Moon Said,  Gerry Powell, explains who plant medicine is for, how plant medicine heals (if done correctly), and how it can benefit your wellness journey. Discover the truth about plant medicine as Gerry debunks myths and shares how it has the power to help you come face to face with the reality of truth about who you are and your purpose in life. Learn how plant medicine has helped Gerry and visitors of Rhythmia find their miracle and change their lives' trajectory for the better.   Kyle Kingsbury What can breathwork, hedonic calendaring, and plant medicine ceremonies teach you about your actual self, your fears, and your spirituality? In this next clip from episode 219, retired American professional mixed martial artist and now Director of Human Optimization at Onnit, Kyle Kingsbury, reveals that it's okay and necessary to set healthy boundaries when you truly need it in order to let go of those pent-up thoughts and emotions so that they can no longer consume your energy.  As you listen, you'll discover how you can satisfy the need for ‘more' based on what makes you feel good, whole, and happy.   Aubrey Marcus  In episode 196, CEO of Onnit and the author of Own The Day, Own Your Life, Aubrey Marcus, reminds us that we have the power to move on from the past. We were not the same people that we were before and we don’t have to allow our past to define and label us. It is Aubrey’s mission to help each person understand that they have the ability to make their life their own. By giving people the tools to transform their work, relationships, and wellness, he’s helping create a world of optimized individuals who are looking to become the best versions of themselves.   Mary Shores How can you stop your negative thought patterns in order to rewrite your story and live life to its fullest?  From episode 191, author of Conscious Communications, Mary Shores, has a mission to help people clear themselves from their financial debt and feel good about doing it. Each day she is helping people cleanse their minds and get back in alignment with who they are and what they want from life. From debt collector and business owner, she was able to go on a spiritual path in order to help herself and others change their beliefs about what they can and cannot do.   Join Us For 2019 We've arrived to the end of 2018, and there are hundreds of more episodes to come filled with energy and inspiration. I want to thank so many incredible humans who have helped make 2018 another amazing year for Wellness Force My heart is full for everyone who has made this podcast possible, so I know I'm gonna miss a ton of people in these shout-outs to Buzzy Torek and the whole team over at Epicast Network for making the show sound so powerful, to Shanna at Organifi for believing in us and supporting the show with trustworthy products, to Lauren Bryant for all you do in our Wellness Force Community, to my brother, James, for being the example of how to live from the heart, to my mother, Mary, and father, Dan, for giving me the gift of life, and to my teachers: Alan Watts, Napoleon Hill, Abraham Hicks, Carl Sagan, Jason Silva, Jade Teta, Robb Wolf, Rythmia, Mary Shores and countless more, both alive and who are watching all of us from the expanse of the universe. To every single guest we’ve had on the show. And, last but not least, to all my #WellnessWarriors in the Wellness Force Family: I see you, I love you, and I support what you are doing to raise the consciousness our world needs right now. My friend, I know you already know this, but thank you for being here and being a part of this community who are up to big things, and doing the physical and emotional work needed to live life well. Until I see you again real soon, I’m wishing you love and wellness.  - Josh Trent        Join The Wellness Warrior VIP Club:  **Click on the photo above to get exclusive discounts on new wellness tools, be first in line for new podcasts, get access to invite-only events, and so much more.**   More Top Episodes 226 Paul Chek: The Revolution Is Coming (3 Part Series) 131 Drew Manning: Emotional Fitness 129 Gretchen Rubin: The Four Tendencies  183 Dr. Kyra Bobinet: Brain Science 196 Aubrey Marcus: Own The Day 103 Robb Wolf: Wired To Eat Best of The Best: The Top 10 Guests From over 200 Shows Get More Wellness In Your Life Join the WFR Community on Facebook Tweet us on Twitter: Send us a fun tweet (or a what's up) Comment on the Facebook page Rate & Review Wellness Force  

Ancient cultures have used plant-based medicines to heal humans for centuries. Only since modern times have treatments been designed to keep people on a lifetime schedule of pharmaceuticals. Jeff McNairy, Psy.D., M.P.H. joins Drew to discuss his passion to change medicine for the better and his role at Rythmia Life Advancement Center in Costa Rica. Dr. McNairy explains the chemical components of ayahuasca tea, drug interactions and possible side effects, and how Rythmia stays fully in compliance with the Ministry of Health in Costa Rica. If you think drinking ayahuasca tea is just something hippies do you want to listen to this episode.   If you like the podcast subscribe & review it on iTunes | Stitcher.   Key Takeaways:   [5:04] How Ice-T influenced Jeff to follow his passion to change the field of medicine for the better.     [7:46] Jeff started his career working with kids to empower them and increase their self-esteem.   [15:12] Jeff has seen plant-based medicine push people to make dynamic internal shifts.   [21:12] Rhythmia in Costa Rica is a bridge between ancient, plant-based medicine and modern, westernized medicine.   [24:47] Possible risks of taking plant-based medicines without the proper protocols.   [27:28] How is ayahuasca tea made and how does it affect the body?   [30:29] Is it possible to have an ayahuasca experience in the U.S. and what do U.S.-based doctors think about it?   Sponsors: Complete Wellness Supplements — Shop for Drew’s Hand-formulated, Pre-workout Greens, Apple Cider Vinegar in Pill Form, and now Keto Boost with Cordyceps and Beet Root Powder Dry Farm Wines — Use this link for a bottle of wine for $.01 with any order   Mentioned in This Episode: Dr. Jeff McNairy Website Rythmia Spiritual Retreat Center Listen to Episode 166: Drew Does Ayahuasca Fit2Fat2Fit Take the Fit2Fat2Fit Podcast Listener Survey Fit2Fat2Fit on Facebook Fit2Fat2Fit Book Drew on Social Media: @fit2fat2fit Email Drew: Drew@fit2fat2fit.com @CompleteWellness on Facebook

Welcome back to another episode. Today we're going to be talking about something that's really cool. I think you're really going to like it. I'm so excited to share with you. Are you almost ready? Let's get into it. Today we're going to be talking about something a little bit more esoteric but also really freaking awesome at the same time. Follow me on Instagramaaron_doughty44 Subscribe to the Show on iTunes herecan you leave a review for the podcast? I would soo appreciate it  You can leave a review here Instead of the effort because I'm not sure if iTunes penalizes for saying curse words. I don't think so. Joe Rogan, I think does it all the time. I'm pretty sure he's okay. I just made a YouTube video on this, so I'm excited to talk about this. Just a little recap. I just got back a couple of days ago from California. I went to San Diego for a couple of days with my buddy Victor. We went to San Diego. We went to a whole bunch of good places to eat. We got some work done. We brainstorm some ideas, what we do, Victor Oddo, he's a YouTuber and my best friend. We went jet skiing. That was really cool. We went jet skiing, we went. Jet Skiing is very interesting by interesting. Went to mission bay in San Diego. It's a really cool victory and I each got our own. It's funny, we were going to get one and then take turns, but we're so glad that we got to because I would have been kind of funny. One of us holding each other around and just going from one from one place to the other. We were on the jet ski going around and there were these two, these two girls that like fell out their jet ski and we came to save the day. Victor did a little bit more than I did or a lot more than I did. He got off the jet ski and we help these girls get back on them. We spent a good amount of time helping out at people, you know, trying to add value, we still had a lot of fun. We got those things up to like 40 something miles an hour maybe. I think Victor got his up to 50. I can only get mine up to like 40 something miles an hour. It's fast. When you go for some miles on top of the ocean, you're like, damn, damn, that's kind of what that's going to look like. And what else do we do? Then we went up to, uh, basically we went for two days and then after those two days what happened is we went up to Los Angeles, we met up at Alexandra who's a good friend of ours. We're all going to Rhythmia place in Costa Rica soon. I wanted Viktor to meet Leo orcs. He hasn't met her yet and is one of my good friends. We all met up and everything went really well. They got along great as very happy and then we would some really good Mediterranean a spot. And then what I did is I flew Victor back because originally Victor and I were going to drive back to Vegas together, but another company hit me up a continent. Got a crew of people I've been watching on YouTube for a while that I respect what they do. And I ended up meeting up with them and a film and a video together that'll be coming out next week. It's gotten named Owen. Uh, so it was really cool. And then I was up there so I was getting to see. I mean they were very successful at what they do. I was able to go to his house as he has a house in the Hollywood Hills. It's like five stories. It's overlooking like the whole Los Angeles. And we filmed a video up there is really cool. We made a video on understanding the low vibration energy and how to transcend it. A guy named Julian, me and Owen. We got a good video coming out soon. I don't know when this episode will come out, but that actually that, that video will probably come out soon after the APP, the podcast episode comes out, so be on the lookout for it. It's going to be on low vibrational energy and how to transcend it. I'm kind of like that. It's kind of a cool acronym. I went there and I hung out and we talked about business. We talked about a whole bunch of different stuff and kind of helping each other out. And he was,

Welcome back to another episode. Today we're going to be talking about something that's really cool. I think you're really going to like it. I'm so excited to share with you. Are you almost ready? Let's get into it. Today we're going to be talking about something a little bit more esoteric but also really freaking awesome at the same time. Follow me on Instagramaaron_doughty44 Subscribe to the Show on iTunes herecan you leave a review for the podcast? I would soo appreciate it  You can leave a review here Instead of the effort because I'm not sure if iTunes penalizes for saying curse words. I don't think so. Joe Rogan, I think does it all the time. I'm pretty sure he's okay. I just made a YouTube video on this, so I'm excited to talk about this. Just a little recap. I just got back a couple of days ago from California. I went to San Diego for a couple of days with my buddy Victor. We went to San Diego. We went to a whole bunch of good places to eat. We got some work done. We brainstorm some ideas, what we do, Victor Oddo, he's a YouTuber and my best friend. We went jet skiing. That was really cool. We went jet skiing, we went. Jet Skiing is very interesting by interesting. Went to mission bay in San Diego. It's a really cool victory and I each got our own. It's funny, we were going to get one and then take turns, but we're so glad that we got to because I would have been kind of funny. One of us holding each other around and just going from one from one place to the other. We were on the jet ski going around and there were these two, these two girls that like fell out their jet ski and we came to save the day. Victor did a little bit more than I did or a lot more than I did. He got off the jet ski and we help these girls get back on them. We spent a good amount of time helping out at people, you know, trying to add value, we still had a lot of fun. We got those things up to like 40 something miles an hour maybe. I think Victor got his up to 50. I can only get mine up to like 40 something miles an hour. It's fast. When you go for some miles on top of the ocean, you're like, damn, damn, that's kind of what that's going to look like. And what else do we do? Then we went up to, uh, basically we went for two days and then after those two days what happened is we went up to Los Angeles, we met up at Alexandra who's a good friend of ours. We're all going to Rhythmia place in Costa Rica soon. I wanted Viktor to meet Leo orcs. He hasn't met her yet and is one of my good friends. We all met up and everything went really well. They got along great as very happy and then we would some really good Mediterranean a spot. And then what I did is I flew Victor back because originally Victor and I were going to drive back to Vegas together, but another company hit me up a continent. Got a crew of people I've been watching on YouTube for a while that I respect what they do. And I ended up meeting up with them and a film and a video together that'll be coming out next week. It's gotten named Owen. Uh, so it was really cool. And then I was up there so I was getting to see. I mean they were very successful at what they do. I was able to go to his house as he has a house in the Hollywood Hills. It's like five stories. It's overlooking like the whole Los Angeles. And we filmed a video up there is really cool. We made a video on understanding the low vibration energy and how to transcend it. A guy named Julian, me and Owen. We got a good video coming out soon. I don't know when this episode will come out, but that actually that, that video will probably come out soon after the APP, the podcast episode comes out, so be on the lookout for it. It's going to be on low vibrational energy and how to transcend it. I'm kind of like that. It's kind of a cool acronym. I went there and I hung out and we talked about business. We talked about a whole bunch of different stuff and kind of helping each other out. And he was,

Welcome back to another episode. Today we're going to be talking about something that's really cool. I think you're really going to like it. I'm so excited to share with you. Are you almost ready? Let's get into it. Today we're going to be talking about something a little bit more esoteric but also really freaking awesome at the same time. Follow me on Instagramaaron_doughty44 Subscribe to the Show on iTunes herecan you leave a review for the podcast? I would soo appreciate it  You can leave a review here Instead of the effort because I'm not sure if iTunes penalizes for saying curse words. I don't think so. Joe Rogan, I think does it all the time. I'm pretty sure he's okay. I just made a YouTube video on this, so I'm excited to talk about this. Just a little recap. I just got back a couple of days ago from California. I went to San Diego for a couple of days with my buddy Victor. We went to San Diego. We went to a whole bunch of good places to eat. We got some work done. We brainstorm some ideas, what we do, Victor Oddo, he's a YouTuber and my best friend. We went jet skiing. That was really cool. We went jet skiing, we went. Jet Skiing is very interesting by interesting. Went to mission bay in San Diego. It's a really cool victory and I each got our own. It's funny, we were going to get one and then take turns, but we're so glad that we got to because I would have been kind of funny. One of us holding each other around and just going from one from one place to the other. We were on the jet ski going around and there were these two, these two girls that like fell out their jet ski and we came to save the day. Victor did a little bit more than I did or a lot more than I did. He got off the jet ski and we help these girls get back on them. We spent a good amount of time helping out at people, you know, trying to add value, we still had a lot of fun. We got those things up to like 40 something miles an hour maybe. I think Victor got his up to 50. I can only get mine up to like 40 something miles an hour. It's fast. When you go for some miles on top of the ocean, you're like, damn, damn, that's kind of what that's going to look like. And what else do we do? Then we went up to, uh, basically we went for two days and then after those two days what happened is we went up to Los Angeles, we met up at Alexandra who's a good friend of ours. We're all going to Rhythmia place in Costa Rica soon. I wanted Viktor to meet Leo orcs. He hasn't met her yet and is one of my good friends. We all met up and everything went really well. They got along great as very happy and then we would some really good Mediterranean a spot. And then what I did is I flew Victor back because originally Victor and I were going to drive back to Vegas together, but another company hit me up a continent. Got a crew of people I've been watching on YouTube for a while that I respect what they do. And I ended up meeting up with them and a film and a video together that'll be coming out next week. It's gotten named Owen. Uh, so it was really cool. And then I was up there so I was getting to see. I mean they were very successful at what they do. I was able to go to his house as he has a house in the Hollywood Hills. It's like five stories. It's overlooking like the whole Los Angeles. And we filmed a video up there is really cool. We made a video on understanding the low vibration energy and how to transcend it. A guy named Julian, me and Owen. We got a good video coming out soon. I don't know when this episode will come out, but that actually that, that video will probably come out soon after the APP, the podcast episode comes out, so be on the lookout for it. It's going to be on low vibrational energy and how to transcend it. I'm kind of like that. It's kind of a cool acronym. I went there and I hung out and we talked about business. We talked about a whole bunch of different stuff and kind of helping each other out. And he was,

Welcome back to another episode. Today we're going to be talking about something that's really cool. I think you're really going to like it. I'm so excited to share with you. Are you almost ready? Let's get into it. Today we're going to be talking about something a little bit more esoteric but also really freaking awesome at the same time. Follow me on Instagramaaron_doughty44 Subscribe to the Show on iTunes herecan you leave a review for the podcast? I would soo appreciate it  You can leave a review here Instead of the effort because I'm not sure if iTunes penalizes for saying curse words. I don't think so. Joe Rogan, I think does it all the time. I'm pretty sure he's okay. I just made a YouTube video on this, so I'm excited to talk about this. Just a little recap. I just got back a couple of days ago from California. I went to San Diego for a couple of days with my buddy Victor. We went to San Diego. We went to a whole bunch of good places to eat. We got some work done. We brainstorm some ideas, what we do, Victor Oddo, he's a YouTuber and my best friend. We went jet skiing. That was really cool. We went jet skiing, we went. Jet Skiing is very interesting by interesting. Went to mission bay in San Diego. It's a really cool victory and I each got our own. It's funny, we were going to get one and then take turns, but we're so glad that we got to because I would have been kind of funny. One of us holding each other around and just going from one from one place to the other. We were on the jet ski going around and there were these two, these two girls that like fell out their jet ski and we came to save the day. Victor did a little bit more than I did or a lot more than I did. He got off the jet ski and we help these girls get back on them. We spent a good amount of time helping out at people, you know, trying to add value, we still had a lot of fun. We got those things up to like 40 something miles an hour maybe. I think Victor got his up to 50. I can only get mine up to like 40 something miles an hour. It's fast. When you go for some miles on top of the ocean, you're like, damn, damn, that's kind of what that's going to look like. And what else do we do? Then we went up to, uh, basically we went for two days and then after those two days what happened is we went up to Los Angeles, we met up at Alexandra who's a good friend of ours. We're all going to Rhythmia place in Costa Rica soon. I wanted Viktor to meet Leo orcs. He hasn't met her yet and is one of my good friends. We all met up and everything went really well. They got along great as very happy and then we would some really good Mediterranean a spot. And then what I did is I flew Victor back because originally Victor and I were going to drive back to Vegas together, but another company hit me up a continent. Got a crew of people I've been watching on YouTube for a while that I respect what they do. And I ended up meeting up with them and a film and a video together that'll be coming out next week. It's gotten named Owen. Uh, so it was really cool. And then I was up there so I was getting to see. I mean they were very successful at what they do. I was able to go to his house as he has a house in the Hollywood Hills. It's like five stories. It's overlooking like the whole Los Angeles. And we filmed a video up there is really cool. We made a video on understanding the low vibration energy and how to transcend it. A guy named Julian, me and Owen. We got a good video coming out soon. I don't know when this episode will come out, but that actually that, that video will probably come out soon after the APP, the podcast episode comes out, so be on the lookout for it. It's going to be on low vibrational energy and how to transcend it. I'm kind of like that. It's kind of a cool acronym. I went there and I hung out and we talked about business. We talked about a whole bunch of different stuff and kind of helping each other out. And he was,

Gerard is an American entrepreneur. In 2015, Powell founded Rythmia Life Advancement Center in Costa Rica, after an experience with plant medicine helped him overcome depression. The medically-licensed luxury retreat center focuses on spiritual awakening and facilitates plant medicine journeys.   To joins us at Rythmia in November click HERE  

Dr. Paul Wang:           Welcome to the monthly podcast On the Beat for Circulation Arrhythmia and Electrophysiology. I'm Dr Paul Wang, editor-in-chief, with some of the key highlights for this month's issue. We'll also hear from Dr. Suraj Kapa reporting on new research from the latest journal articles in the field.                                                 In our first article, Barry Maron associates report on the long term clinical course of hypertrophic cardiomyopathy patients following ICD therapy for ventricular arrhythmias. They studied a cohort of 486 high-risk hypertrophic cardiomyopathy patients with ICDs from eight international centers. Of these 486 patients over 6.4 years, 94 patients or 19% experienced appropriate ICD interventions, terminating VT or VF. Of the 94 patients receiving appropriate ICD therapy, 87 were asymptomatic or only mildly symptomatic at the time of appropriate ICD interventions. Of these 87 patients, 74 or 85% remained in classes one or two without significant change in clinical status of the subsequent 5.9 years up to 22 years. Among the 94 patients, there was one sudden death in three patients who died from non arrhythmic hypertrophic cardiomyopathy related processes. Post ICD intervention, freedom from hypertrophic cardiomyopathy, mortality was 100% at one year, 97% at five years, and 92% at 10 years, distinctly lower than the risk of ischemic or non ischemic cardiomyopathy in ICD trials.                                                 Hypertrophic cardiomyopathy patients with ICDs interventions reported the heightened anxiety and expectation of future shocks. However, they did not affect general psychological well-being or quality of life. The authors concluded that in hypertrophic cardiomyopathy, unlike ischemic heart disease, prevention of sudden death with ICD therapies unassociated with a significant increase in cardiovascular morbidity and mortality, nor transformation into heart failure deterioration, ICD therapy does not substantially impair overall psychological and physical well-being. In our next article, Abdulla Damluji and associates examined the cost of hospitalizations for cardiac arrest using the US nationwide inpatient sample from 2003 to 2012. Using the log transformation of inflation adjusted costs the authors examined 1,387,396 patients who were hospitalized after cardiac arrest. They had a mean age of 66 years. Inpatient procedures included coronary angiography in 15%, PCI in 7%, intra-aortic balloon pump in 4.4%, therapeutic hypothermia in 1.1%, and mechanical circulatory support in 0.1% of patients.                                                 Notably the rates of therapeutic hypothermia increased from 0 in 2003 to 2.7 in 2012, p less than 0.001. Both hospital charges inflation adjusted costs linear increased over time. In a multi-variant analysis predictors of inflation adjusted costs included large hospitals size, urban teaching hospital, and length of stay. Among co-morbidities, atrial fibrillation or fluid and electrolytes imbalance were the most common associated with cost. The authors found that during the period between 2003 and 2012 post cardiac arrest, hospitalizations had a steady rise and associated healthcare costs likely related to increase length of stay, medical procedures and systems of care.                                                 In our next paper, Peter Huntjens and associates examined intrinsic interventricular dyssynchrony as a predictor of human dynamic response to cardiac resynchronization. The authors use a cardiovascular computational model CircAdapt to characterize the isolated effect of intrinsic interventricular or intraventricular activation on resynchronization therapy response that is the change in LV dP/dt max. The simulated change in LV dP to dt max had a range of 1.3 to 26.5% increased considerably with increasing inter ventricular dyssynchrony. In contrast, the isolated effect of intra ventricular dyssynchrony was limited with the change in the LV dP/dt max range and the left ventricle from 12.3 to 18.3% in the right ventricle from 14 to 15.7%.                                                 Secondly, electrocardiographic imaging derived activation characteristics of 51 CRT candidates were used to create individual models of ventricular activation in CircAdapt. The model predicted change in LV dP/dt max was close to the actual value in left bundle branch block patients with 2.7% difference between measured and simulated when only intrinsic interventricular dyssynchrony was personalized. Among non left bundle branch block patients a change in LV dP/dt max was systematically over predicted by CircAdapt with a 9.2% difference between measured and simulated. Adding intra ventricular activation to the model did not improve the accuracy of response prediction. The authors found that computer revealed intrinsic interventricular dyssynchrony is the dominant component of the electrical substrate driving the response to CRT.                                                 In the next paper Kenji Kuroki and associates examined the use of voltage limit adjustment of substrate mapping and fast Fourier transform analysis of local ventricular bipolar electrograms during sinus rhythm to predict VT isthmuses. They performed these studies and nine post infarction patients who underwent catheter ablation for total of 13 monomorphic ventricular tachycardias. Relatively higher voltage areas on electroanatomical map or defined as high voltage channels, which were further classified as full or partial if the entire or more than 30% of the high voltage channel was detectable. 12 full high voltage channels were identified in seven of nine patients. Relatively higher fast Fourier transform areas were defined as high frequency channels, which were located on seven of 12 full high voltage channels. Five VT isthmuses or 71% were included in the seven full high voltage channels positive in high frequency channel positive sites.                                                 While no VT isthmuses were found in five full high voltage channel positive but high frequency channel negative sites, high frequency channels were identical to 9 out of 16 partial high voltage channels. Eight VT isthmuses or 89% were included in nine partial high voltage channel positive in high frequency channel positive sites, whereas no VTs isthmuses were found in the seven partial high voltage channel positive and high frequency channel negative sites.                                                 All high voltage channel positive in high-frequency channel positive sites predicted VT isthmus with a sensitivity of 100% and specificity of 80%. The authors concluded that based on this small series that combined use of voltage, limited adjustment and fast Fourier transform analysis may be useful method to detect VT isthmuses.                                                 In the next study, John Whitaker and associates examined the use of lesion index, LSI index, a proprietary algorithm combining contact force, radio-frequency application duration, and RF current. Cardiac CT was used to assess atrial tissue thickness. Ablation lines two to three per animal were created in the right atrium in seven mini pigs with point lesions using 25 watts of energy. Two weeks after the ablation, serial sections of targeted atrial tissue or examine histologically to identify gaps and transmural ablation. LSI guidelines had a lower incidence of histological gaps. Four gaps in the 69 catheter moved or 5.8% compared to ablation using LSI plus two millimeter lines in which there is seven gaps in 33 catheter moves or 21.2% and using LSI plus four millimeter lines in which there are 15 gaps in 23 moves or 65.2% p less than 0.0. The change in LSI was calculated retrospectively is a distance between two adjacent lesions above the mean LSI of the two lesions. Changing LSI values of 1.5 or less were associated with no gaps in transmural ablation.                                                 The authors concluded that in this mod of chronic atrial ablation delivery of uninterrupted transmural linear lesions may be facilitated using LSI to guide catheter movement. When change in LSI between adjacent legions is 1.5 millimeters or lower, no gaps in atrial linear lesions should be expected.                                                 In our next paper, Matthew Bennett and associate examined whether their response to antitachycardia pacing in patients with ICD could further discriminate ventricular from super ventricular arrhythmias in patients receiving ATP in the RAFT trial. The RAFT trial randomized 1,798 patients with New York Heart Association class two or three heart failure, left ventricular ejection fraction less than or equal to 30%, in QRS duration 120 millisecond or greater, to an ICD plus or a minus cardiac resynchronization. Beginning with 10,916 ATP attempts for 8,150 tachycardia episodes in 924 patients, the author's excluded tachycardias where ATP terminated the episode or were the specific etiology tachycardia was uncertain. In this study, they analyzed 3,676 ATP attempts delivered to 2,046 tachycardia episodes in 541 patients. The authors found that a shorter difference between the post pacing interval is PPI minus TCL, was more likely to be associated with VT than SVT, mean of 138.1 milliseconds for VT and 277.4 milliseconds for SVT p, less than 0.001. A PPI minus TCL value of less than or equal to 300 milliseconds had a sensitivity in 97.4% and a specificity of 28.3% for VT.                                                 The authors concluded that specifically the PPI minus TCL following antitachycardia pacing may help distinguish ventricular from supraventricular arrhythmias.                                                 In the next study, Shailee Shah and Amr Barakat and associates examined the outcomes after repeat AF ablation. The authors examined 137 patients out of a total of 10,378 patients undergoing Afib ablation who had had initial long-term success defined from recurrent arrhythmias for greater than 36 months off anti-arrhythmic drugs in subsequent underwent repeat ablation for recurrent atrial fibrillation. The median arrhythmia free period that define long-term success was 52 months. In redo-ablations reconnection of at least one of the pulmonary veins was found in 111 or 81% of patients. Additional non PV ablations were performed in 127 or 92.7% of patients. After a mean follow-up of 17 months, 103 patients or 75% were arrhythmia-free, 79 off anti-arrhythmics, and 24 on arrhythmics. The authors found that repeat ablations with re-isolation to the point of veins and modifying the atrial substrate had a good success rate.                                                 In the next article Qiongling Wang and associates hypothesized that genetic inhibition of CaMKII oxidation in a mouse model of Duchenne muscular dystrophy can alleviate abnormal calcium homeostasis thus preventing ventricular arrhythmias. The authors tested whether the selective loss of oxidation of the CaMKII effects ventricular arrhythmias in the mouse model of Duchenne muscular dystrophy. Genetic inhibition of ox-CaM kinase II by knocking replacement of the regulatory domain methionines with valines, which we'll call MMVV, prevented ventricular tachycardia in the mdx mice. Confocal calcium imaging of ventricular myocytes, isolated from the mdx MMVV mice revealed normalization of intra-calcium release events compared to myocytes from the mdx mice. Abnormal action potentials as assessed by optical mapping mdx were also alleviated by genetic inhibition of ox-CaMK II. Knockout of the NADPH oxidase regulatory sub-unit P 47 Fox normalized elevated ox-CaMK II, repaired intracellular calcium hemostasis and rescued inducible ventricular arrhythmias in the mdx mice. The authors concluded that inhibition of ROS or ox-CaMK II protects against pro-arrhythmic intracellular calcium handling, preventing ventricular arrhythmias in a mouse model of Duchenne muscular dystrophy.                                                 In the next article, Kyohei Marume and Teruo Noguchi and associates examined whether the combination of QRS duration of 120 milliseconds or greater in late gadolinium enhancement is a precise prognostic indicator for the primary endpoint of all cause death and a composite of sudden cardiac death or aborted sudden cardiac death in 531 patients with dilated cardiomyopathy. They also analyzed the association between the combination of late gadolinium enhancement and increased QRS duration in these end points among patients with a class one indication for implantable defibrillator. The author's divided study patients in three groups according to late gadolinium enhancement in QRS duration. Two negative indices that is late gadolinium enhancement negative and narrow QRS, one positive index with either late gadolinium enhancement positive or wide QRS or two positive indices late gadolinium positive and wide QRS and followed them for 3.8 years. Multiple variable Cox regression analysis identified to positive indices as significant predictors of all cause death. A hazard ratio of 4.29 p equals 0.026. Among the 317 patients with a class one indication for ICD, the five year event rate of sudden cardiac death or aborted sudden cardiac death was lowest in the two negative indices groups, 1.4%. With propensity score matching cohorts the two negative indices group had a significant lower event rate of sudden cardiac death or aborted sudden cardiac death than to two other groups hazard ratio 0.2, p equals 0.046.                                                 The authors concluded that the combination of late gadolinium enhancement in wide QRS provides additional prognostic stratification compared to late gadolinium enhancement status alone.                                                 In the next study, Matthew Sulkin and associates examined whether a novel local impedance measurement on an ablation catheter identifies catheter tissue coupling and is predictive of lesion formation. The author's first studied explanted hearts, 10 swine, and then in vivo 10 swine, using an investigational electro anatomical mapping system that measures impedance from an ablation catheter with mini electrodes incorporated into the distal electrode. Rhythmia and Intellanav, Boston Scientific.                                                 Explanted tissue was placed in a warmed 37 degree celsius saline bath mounted on a scale, and the local impedance was measured 15 millimeters away from the tissue to five millimeters of catheter tissue compression at multiple catheter angles. Lesions were created for 31 and 50 watts from 5 to 45 seconds for an N of 70. During in vivo valuation of the local impedance measurements of the myocardium 90 and blood pool 30 were guided by intracardiac ultrasound while operators were blinded to the local impedance data. Lesions were created with 31 and 50 watts for 45 seconds in the ventricle with an n of 72. The local impedance of myocardium, which was 119.7 ohms, was significantly greater than in blood pool 67.6 ohms the p of less than 0.01. Models that incorporate local impedance drop to predict lesion size had better performance that models incorporate force time integral r squared of 0.75 versus r squared of 0.54 and generator impedance drop r squared of 0.2 versus r squared of 0.58. Steam pops displayed a significantly higher starting local impedance and a larger change in local impedance compared to successful RF applications, p less than 0.01.                                                 The authors concluded that local impedance recorded for miniature electrodes provides a valuable measure of catheter tissue coupling and the change in local impedance is predictive of lesion formation during RF ablation.                                                 In the next paper, Boaz Avitall and associates found that the rising impedance recorded from a ring electrode placed two millimeters from the cryoballoon signifies ice formation covering the balloon surface and indicates ice expansion. The authors studied 12 canines in a total of 57 pulmonary veins, which were targeted for isolation. Two cryoapplications were delivered per vein with a minimum of 90 and a maximum 180 second duration. Cryoapplications was terminated upon reaching a 500 ohm change from baseline. Animals recovered 38 plus or minus six days post procedure, and the veins were assessed electrically for isolation. Heart tissue was histological examined. Extra cardiac structures were examined for damage. Pulmonary vein isolation was achieved in 100% of veins if the impedance reached 500 ohms in 90 to 180 seconds. When the final impedance was between 200 and 500 ohms within 180 seconds of freeze time, pulmonary vein isolation was achieved in 86.8%. For impedance of less than 200 ohms pulmonary vein isolation was achieved in 14%. No extra cardiac damage was recorded. The authors found that impedance rise of 500 ohms at less than 90 seconds with a freeze time of 90 seconds resulted in 100% pulmonary vein isolation.                                                 In our final papers Sally-Ann Clur and associates examined left ventricular isovolumetric relaxation time as the potential diagnostic marker for fetal Long QT Syndrome. Left ventricular isovolumetric contraction time, ejection time, left ventricular isovolumetric relaxation time, cycle length, and fetal heart rate were measured using pulse doppler wave forms in fetuses. Time intervals were expressed as percentage of cycle length, and the left ventricular myocardium performance index was calculated. Single measurements were stratified and compared between Long QT Syndrome fetuses and controls. Receiver operator curves were reformed for fetal heart rate in normalized left ventricular isovolumetric relaxation time. A linear mixed effect model including multiple measurements was used to analyze fetal heart rate, the left ventricular iso volume metric relaxation time, and the left ventricular myocardial performance index. There were 33 Long QT fetuses in 469 controls. In Long QT fetuses the left ventricular isovolumetric relaxation time was prolonged in all groups, p less than 0.001, as was the left ventricular isovolumetric relaxation time.                                                 The best cutoff to diagnose Long QT syndrome was the normalized left ventricular isovolumetric relaxation time greater than equal to 11.3 at less than or equal to 20 weeks, giving a sensitivity in 92% and a specificity of 70%. Simultaneous analysis of the normalized left ventricular isovolumetric relaxation time and fetal heart rate improved the sensitivity and specificity of Long QT Syndrome, AUC of 0.96. The normalized left ventricular isovolumetric relaxation time, the left ventricular myocardial performance index, and fetal heart rate trends differed significantly between Long QT Syndrome fetuses and controls throughout gestation.                                                 The authors concluded that left ventricular volumetric relaxation time is Prolonged QT fetuses. Findings of a prolonged normalize left ventricular isovolumetric relaxation time, and sinus bradycardia can improve the prenatal detection of fetal Long QT Syndrome.                                                 That's it for this month, but keep listening. Suraj Kapa will be surveying all journals for the latest topics of interest in our field. Remember to download the podcasts On the Beat. Take it away Suraj. Suraj Kapa:                          Thank you, Paul and welcome back to On the Beat were we will be summarizing hard-hitting articles across the entire electrophysiologic literature. Today we'll be starting within the realm of atrial fibrillation where we're review an article within the realm of anticoagulation and stroke prevention. Quon et al. published in last month's issue of JACC cardiac electrophysiology on anticoagulant use and risk of ischemic stroke and bleeding in patients with secondary atrial fibrillation. It is well known that use of anticoagulation in atrial fibrillation can reduce overall thromboembolic outcomes. However, its role in secondary atrial fibrillation is unclear. Thus, the authors sought to evaluate the effects anticoagulant use on stroke and bleeding risk. Amongst those where atrial fibrillation occurred in the setting of acute coronary syndrome, pulmonary disease, or sepsis. Amongst around 2300 patients evaluated retrospectively there was no evidence of a lower incidence of ischemic stroke among those treated with anticoagulants compared to those who are not.                                                 However, anticoagulation was associated with a higher risk of bleeding in those with new onset AF associated with acute pulmonary disease. The authors suggest as a result that there is unclear overall benefit for long-term anticoagulation in patients with presumed secondary atrial fibrillation. The difficulty in assessing this is how to define secondary atrial fibrillation. However, in many studies patients who developed in the setting of acute illness still had a high risk of developing quote unquote clinically significant AF in long-term follow-up. However, this was not necessarily absolute as many patients not necessarily develop AF that could be considered clinically significant. Thus, the clinical question that arises is: how long should we treat a patient with anticoagulation when they have presumed secondary atrial fibrillation. These data seem to suggest that there may be no net overall benefits. In other words, all-comers with secondary atrial fibrillation should not necessarily be forever treated with anti-coagulation. However, this slightly requires clinical trials to evaluate further.                                                 Next we delve into the realm of cardiac mapping and ablation where we view an article by Gaita et al. entitled 'Very long-term outcome following transcatheter ablation of atrial fibrillation. Are results maintained after 10 years of follow-up?', published in Europace last month. While pulmonary vein isolation is a widely accepted approach for treatment of atrial fibrillation, most reported studies review outcomes in terms of freedom of AF over a relatively short time period, generally two to five years. However longer term follow up is inconsistently reported. Gaita et al. sought to review 10 year outcomes amongst 255 patients undergoing ablation in a single center. They noted 52% remainder arrhythmia-free amongst a mixed cohort of both paroxysmal and persistent patients while 10% progressed to permanent atrial fiBrillation. They found that absence of increases in blood pressure, BMI, and fasting glucose was protective against an arrhythmia recurrence.                                                 These findings suggest that in a relatively small cohort of patients limited to a single center that even long-term outcomes after pulmonary vein isolation are generally quite good, exceeding 50%. However, future freedom from atrial fibrillation is heavily tied to control of other risk factors. In other words, if a patient is going to have poor control of diabetes, blood pressure, or gain weight, the benefit of their pulmonary vein isolation over long-term follow-up is likely less. These data thus highlight both the potential long-term benefit of PVI, but also the importance of counseling patients regarding the need for continued management and control of future and existing risk factors.                                                 Staying within the realm of atrial fibrillation we next review an article by Weng et al. entitled 'Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation' published in last month's issue of circulation. The probability of detecting atrial fibrillation in patients based on clinical factors and genetic risk is unknown. Weng et al. sought to clarify whether a combination of clinical and polygenic risk scores could be used to predict risk of developing atrial fibrillation over long-term followup in the Framingham Heart Study. Amongst 4,600 individuals, 580 developed incident atrial fibrillation and had an overall lifetime risk of developing atrial fibrillation of 37%. Those are the lowest risk tertile based on clinical risk factor burden and genetic predisposition had a lifetime risk of 22% versus 48% in the highest. Furthermore, a lower clinical risk factor burden was associated with delayed atrial fibrillation onset. In order to identify patients with atrial fibrillation, before negative sequelae such as stroke occur, patient and physician understanding of risk and monitoring needs is necessary. The fact is that it will be great to identify every single patient who has atrial fibrillation before they have a negative sequela of that atrial fibrillation such as ischemic stroke.                                                 However, performing continuous monitoring of all patients with potential negative sequelae of atrial fibrillation is extraordinarily difficult. The reason is it's excessively costly. We cannot monitor the entire population irrespective of whatever the risk factors are. However, if we're able to identify the highest risk cohorts early on before the atrial fibrillation onsets, this may offer opportunities for use of newer cheaper monitors. The work by Weng et al. suggests one such possible approach combines clinical and polygenic risk scores. Actionability of these data, however, remains to be seen and further validation other cohorts is necessary to clarify generalized ability.                                                 The next article we review is published in last month's issue of the Journal of American College of Cardiology by Lopes at al. entitled 'Digoxin and Mortality in Patients With Atrial Fibrillation. Lopes et al. sought to evaluate the impact of the Digoxin on mortality in patients with atrial fibrillation and the association with the Digoxin serum concentration and heart failure status. They value this association in over 17,000 patients. At baseline 32% were receiving Digoxin. Baseline Digoxin use did not associate with risk of death, but even in these patients a serum concentration of greater than 1.2 nanograms per milliliter was associated with a 56% increase in mortality risk. For each .5 nanogram per milliliter increase in oxygen concentration the hazard ratio increased by 19% for overall mortality. This was irrespective of heart failure status. Furthermore, in patients who are newly started in Digoxin over the follow-up period, the risk and death and sudden death was higher. These data suggests a significant risk associated with Digoxin use for management of atrial fibrillation irrespective of heart failure status. Furthermore, serum valleys above 1.2 require close consideration of dose de-escalation. Whether there is any optimal dose, however, from the study is unclear. These data amongst a host of prior data strongly suggest again strategic use of Digoxin  principally for the management of atrial fibrillation.                                                 Moving on within the realm of atrial fibrillation, we review an article published in last month's issue of Circulation Research by Yan et al. entitled Stress Signaling JNK2 Crosstalk with CaMKII Underlies Enhanced Atrial Arrhythmogenesis. In this more acellular based study the mechanism underlying atrial arrhythmogenesis associated with aging was evaluated. Yan et al. sought to figure out whether the stress response JNK in calcium mediated arrhythmias might contribute to atrial arrhythmogenesis in aged transgenic mouse models. They demonstrated significant increased activity of JNK2 and aging atria, those furthermore associated with rhythmic remodeling. This association was mediated through CaMKII and ryanodine receptor channel function, with activation of the former leading to increased calcium leak mediated by the ladder. This in turn related to increase atrial fibrillation likelihood. Identifying novel targets for atrial fibrillation therapy is critical. Given atrial fibrillation is a complex disease process related to a multitude of risk factors it can be assumed that the contribution of any single factor may be mediated through distinct mechanisms.                                                 Aging in particular as well regarded, but considered to be non-modifiable risk factor for atrial fibrillation. Identifying genes or pathways, the immediate aging associated fibrillation, may take the risk of aging as no longer a non-modifiable thing. The finding of the significance of JNK2 and associate downstream effects with AF risks and aging hearts may hold potential in offering unique therapeutic targets.                                                 Finally, within the realm of atrial fibrillation, we're viewing article by Chen et al. in last month's issue of the Journal of the American Heart Association entitled Association of Atrial Fibrillation With Cognitive Decline and Dementia Over 20 Years: The ARIC-NCS Study. Multiple studies have suggested a significant association between atrial fibrillation risk of dementia. However, these studies have limited time follow-up and were often done and predominantly white patients. Thus, the authors sought to use the data from ARIC, the Atherosclerosis Risk in Communities Neurocognitive Study, to assess the risk of cognitive decline associated with atrial fibrillation. Amongst over 12,000 participants, a quarter of whom are black and half of whom are white, they noted 2100 patients developed atrial fibrillation and 1,150 develop dementia over a 20 year follow up period.                                                 There was a significantly greater risk of cognitive decline amongst those who developed atrial fibrillation. In turn incident atrial fibrillation for the follow-up period was associated with a higher risk of dementia even after adjusting for other clinical and cardiovascular risk factors such as incidents that ischemic stroke. These data further strengthened prior evidence of a direct link between atrial fibrillation and risk of cognitive decline and dementia. Understanding this long-term risk raises the need to additionally identify approaches to prevent this occurrence, which in turn is dependent on understanding the underlying mechanisms. The finding that the risk of cognitive decline dementias independent of ischemic stroke events raises concern that either subclinical micro-embolic events or other factors may be playing a role in this risk and in turn raises question as to how best to prevent them. Until better understood, however, the question of whether the association is causal remains to be seen.                                                 Changing gears yet again, we now delve into the realm of ICDs, pacemakers and CRT. Published in last month, issue of Heart Rhythm Tarakji et al. published a paper entitled 'Unrecognized venous injuries after cardiac implantable electronic device transvenous lead extraction.' Overall risk of transvenous lead extraction includes that of potentially fatal venous laceration. The authors sought to evaluate the incidence of venous injury that may be unrecognized based on microscopic study of extracted leads. Amongst 861 leads obtained from 461 patients they noted 80 leads or almost 9%. Amongst 15% of patients showed segments vein on the lead body, most of which were transmural including the tissue layer. However, in terms of clinical significance, only 1% had need for emergent surgical intervention for clinically significant venous laceration. Risk factors for having the entire vein on the lead included age of lead, ICD leads, and the use of the laser sheath.                                                 These findings suggest that there may be a high incidence of subclinical venous injury after lead extraction though rarely resulting clinically apparent sequelae. As would be expected, venous injury, including transmural removal of portions of the vein traversed by the lead, was more common amongst older leads, which generally more often require laser sheets and ICD leads. The question is however, whether this carries any direct clinical implications. One they may be considered is the potential additive risk of an advancing new lead through the same venous channel, particularly in the setting of potential transmural venous injury that already exists.                                                 Next in last month's issue of Heart Rhythm we review an article by Sharma at al. entitled 'Permanent His-bundle pacing as an alternative to biventricular pacing for cardiac resynchronization therapy: A multicenter experience.' The use of resynchronization therapy for treatment of patients with heart failure and wide QRS has been shown to offer morbidity and mortality benefits. However, many patients maybe non-responders, and recent studies on His bundle pacing of suggested potential clinical benefits. His bundle pacing essentially only requires one pacing catheter attached within the region of the His bundle Sharma et al. sought to evaluate the safety and success rates of His bundle pacing for patients who have either failed standard resynchronization therapy or in whom most tried as a primary intervention. They noted His bundle pacing was successful in 90% of patients with reasonable myocardial and His bundle capture thresholds. Patients in both groups exhibits significant narrowing of QRS morphology and improvement in left ventricular ejection fraction from a mean of 30 to 43%. However, a total of seven patients had lead related complications.                                                 These database on a retrospective analysis of two types of patients, those failing standard biventricular therapy, and those on whom his bundle pacing was attempted as a primary modality suggest overall safety and efficacy in a handful of experienced centers. The promise of His bundle pacing is that a may allow for more effective resynchronization than standard approaches. The high rate of success suggests that His bundle pacing maybe both safe and reasonable to pursue. However randomized trials across more centers are needed to fully prove its benefit, particularly as a primary modality of treatments.                                                 Next we review ICDs and chronic kidney disease. In last month's issue of JAMA cardiology by Bansal at al. entitled 'Long-term Outcomes Associated With Implantable Cardioverter Defibrillator in Adults With Chronic Kidney Disease.' While the benefit of ICDs in patients with low EF is widely recognized, modifying factors that may increase risk of death are not as well defined. These include things like advanced age and chronic kidney disease. Bansal et al. sought to evaluate long-term outcomes and ICD therapy in patients with chronic kidney disease. In retrospective study of almost 5,900 ambulatory patients amongst whom 1550 had an ICD, they found no difference in all cause mortality. However, ICD placement was associated with an increased risk of subsequent hospitalization due to heart failure or any cause hospitalization.                                                 In light of recent studies such as DANISH the robust sense of ICD benefit is being questioned. One of the thoughts for the absence of similar benefit to prior studies lies in the improving care of ambulatory heart failure patients. In patients with chronic kidney disease several questions rises to the risk with ICD, including infectious risk in dialysis patients and the concomitant mortality risk with renal dysfunction. The author suggested in retrospective study, no incremental benefit of ICDs in patients with chronic kidney disease and perhaps some element of added risk is related to hospitalization. However, this study has several limitations. It is retrospective and many patients received ICDs may have been perceived to be sicker in some way. Thus care must be taken in interpretation, but consideration of randomized studies to adjudicate benefit are likely necessary.                                                 Finally, within the realm of devices, we reviewed an article by Tayal et al. entitled "Cardiac Resynchronization Therapy in Patients With Heart Failure and Narrow QRS Complexes.' publishing the Journal of American College of Cardiology last month. Several parameters have been stressed to identify benefit of resynchronization therapy in patients with wide QRS include cross correlation analysis with tissue doppler imaging. However, many patients may have evidence in mechanical dyssynchrony even in the absence of an apparent wide QRS thus Tayal et al. sought to evaluate the benefit of resynchronization therapy amongst 807 patients with heart failure and a narrow QRS mean criteria in a randomized study. Of the 807 46% had delayed mechanical activation. Those without delay mechanical activation had underwent we standardization therapy and were associated with worse overall outcomes likely due to new delayed mechanical activation potentially related to CRT pacing. These data support the absence of a role for resynchronization therapy in patients with a narrow QRS. This is expected as resynchronization therapy likely offers the most benefit in patients with mechanical dyssynchrony that results from electrical dyssynchrony.                                                 Since by its very nature resynchronization therapy relies on non physiologic cardiac pacing thus compared to normal cardiac activation the nature of resynchronization pacing is desynchronization. These data support the absence of a role for resynchronization therapy in patients with heart failure and narrow QRS complexes.                                                 Moving on to cellular electrophysiology we review an article by Kozasa et al. published in last month's issue of Journal of Physiology entitled 'HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node.' Heart rate is controlled by an interplay between sympathetic and parasympathetic components. In turn HCN4 abnormalities have been implicated in congenital sick sinus syndrome. The authors sought to clarify the contribution of HCN4 to sinus node autonomic regulation. They created a novel gain-of-function mouse where the HCN4 activity could be modulating from zero to three times normal. They then evaluated ambulatory heart-rate variability and responsive heart rate to vagus nerve stimulation. They found HCN4 over-expression did not increase heart rate, but attenuated heart-rate variability. It also attenuated bradycardic response to vagus nerve stimulation. Knockdown of HCN4 in turn lead to sinus arrhythmia and enhanced parasympathetic response. These data suggest HCN4 attenuates sinus node response to vagal stimuli thus stabilizing spontaneous firing of the node. The clinical application of this remain to be seen but are maybe important in that they highlight a mechanism for a heretofore poorly understood mechanism for how exactly HCN4 abnormalities may lead to sick sinus syndrome.                                                 Within the realm of ventricular arrhythmias we highlighted a number of articles published this past month. The first article we review was published in last month's issue of JACC clinical electrophysiology, entitled characterization of the electrode atomic substrate and cardiac sarcoidosis: correlation with imaging findings of scarring inflammation published by [inaudible 00:41:40] et al. In patients with cardiac sarcoidosis one of the questions is how to define the electronic atomic substrate, particularly before we entered the electrophysiology laboratory. Both active inflammation and replacement fibrosis maybe be seen in patients. The authors evaluated in 42 patients with cardiac sarcoidosis, the association between an abnormal electrograms and cardiac imaging findings including PET and Computed Tomography, as well as Cardiac MRI. They noted that amongst these 40 patients, a total of 21,000 electrograms were obtained, and a total of 19% of these were classified as abnormal. Most of the abnormalities occurred in the basal paravalvular segments and intraventricular septum. They further noted that many of these abnormalities in terms of electrograms were located outside the low voltage areas, particularly as it relates to fractionation. In about 90% of patients they notice late gadolinium enhancements and they noted abnormal FDG uptakes suggesting active inflammation in about 48%.                                                 However, it should be noted that only 29 of the 42 patients underwent cardiac imaging. Segments with abnormal electrograms tended to have more late gadolinium enhancement evidence scar transmurality, and also they noted that the association of abnormal PET scan did not necessarily occur with abnormal electrograms. Thus, they concluded that in patients with cardiac sarcoidosis and ventricular tachycardia pre-procedural imaging with cardiac MRI could be useful in detecting electroanatomic map abnormalities that may in turn be potential targets for substrate ablation. However, they were more likely associated with more scar transmurality and lower degrees of inflammation on PET scanning. These data are important in that they highlight potential non-invasive means by which to understand where substrate might occur in patients with the cardiac sarcoidosis. It is well recognized that cardiac sarcoidosis is associated with increased risk of ventricular arrhythmias. These risks have increased ventricular arrhythmias, might be targetable with ablation. Newer therapies might even offer non invasive means by which to perform ablation in patients best. Thus if we could identify non based on mechanisms of identifying the substrate, this will be even more critical.                                                 The critical findings of this particular paper lie in noting that most of the abnormalities still is in intra ventricular sePtum in basal segments, and also that it is MRI in late gadolinium enhancement and associates more with the abnormal electrograms. Interestingly, the absence of inflammation correlating with the presence of more abnormal electrograms suggests that it is not so much the act of inflammation as being reflected in the endocardial map, but the existence of scar.                                                 Next, again within JACC clinical electrophysiology we review an article by Porta-Sánchez et al. entitled 'Multicenter Study of Ischemic Ventricular Tachycardia Ablation With Decrement Evoked Potential Mapping With Extra Stimulus.' The authors sought to conduct a multicenter study of decrement evoked potential base functional tech ventricular tachycardia substrate modification to see if such mechanistic and physiologic strategies could result in reduction in VT burden. It is noted that really only a fraction of the myocardium in what we presume to be substrate based on the presence of low voltage areas are actually involved in the initiation and perpetuation of VT. Thus if we can identify the critical areas within the presumed substrate for ablation, this would be even a better way of potentially honing in on our targets. They included 20 consecutive patients with ischemic cardiomyopathy. During substrate mapping fractionated late potentials were targeted and an extra stimulus was provided to determine which display decrements. All patients underwent DEEP focus ablation with elimination being correlated with VT non-inducibility after radio-frequency ablation. Patients were predominantly male, and they noted that the specificity of these decrement evoked potentials to detect the cardiac isthmus for VT was better than that of using late potentials alone. They noted 15 of 20 patients were free of any VT after ablation of these targets over six months of follow-up, and there was a strong reduction in VT burden compared to six months pre ablation.                                                 They concluded that detriment evoked potential based strategies towards ablation for ventricular tachycardia might identify the functional substrate and those areas most critical to ablation. They in turn regarded that by its physiologic nature it offers greater access to folks to ablation therapies.                                                 This publication is important in that it highlights another means by which we can better hone in on the most critical regions for substrate evaluation in patients with ventricular tachycardia. The fact is more extensive ablation is not necessarily better and might result in increased risk of harm if we think about the potential effects of longer ablations or more ablation lesions. Thus if we could identify ways of only targeting those areas that are most critical to the VT circuits, we could perhaps short and ablation procedural time, allow for novel ways of approaching targeted ablation with limited amounts of ablation performed, or perhaps even improve overall VT outcomes by knowing the areas that are most critical to ensure adequate ablation therapy provided. However, we need to understand that this is still a limited number of patients evaluated in a non randomized manner. Thus whether or not more extensive ablation performed might have been better is as of yet unclear                                                 Staying within the realm of ventricular tachycardia we review an article published in last month's issue of Heart Rhythm by Winterfield et al. entitled the 'Impact of ventricular tachycardia ablation on healthcare utilization.' Catheter ablation of atrial tachycardia has been well accepted to reduce recurrent shocks in patients with ICDs. However, this is a potentially costly procedure, and thus effect on overall long-term health care utilization remains to be seen. The authors sought to evaluate in a large scale real world retrospective study the effect of VT ablation on overall medical expenditures in healthcare utilization. A total 523 patients met study inclusion criteria from the market scan database. After VT ablation median annual cardiac rhythm related medical expenditures actually decreased by over $5,000. Moreover the percentage of patients with at least one cardiac rhythm related hospitalization an ER visit decreased from 53 and 41% before ablation respectively, to 28 and 26% after ablation. Similar changes we're seeing in number of all cause hospitalizations and ER visits. During the year before VT ablation interestingly there was an increasing rate of healthcare resource utilization, but a drastic slowing after ablation.                                                 These data suggests that catheter ablation may lead to reduced hospitalization in overall healthcare utilization. The importance of these findings lies in understanding why we do the things we do. We can provide a number of therapies to patients, but we seek two different effects. One is the individual effect of improving their particular health. The second thing is trying to avoid increasing healthcare expenditures on a population level and making sure resources are utilized. If we can reduce recurrent hospitalizations and overall healthcare expenditure in patients by providing a therapy in addition to provide individual benefit, this is the optimal situation. These data suggests that VT ablation might provide such a benefits, that in fact it reduces overall healthcare utilization while improving overall outcomes.                                                 Next and finally within the realm of ventricular arrhythmias, we review more on the basic side the role of Titin cardiomyopathy leads to altered mitochondrial energetics, increased fibrosis and long-term life-threatening arrhythmias, published by Verdonschot et al. in last month's issue of European Heart Journal. It is known now that truncating Titin variants might be the most prevalent genetic cause of dilated cardiomyopathy. Thus, the authors sought to study clinical parameters and long term outcomes related to Titin abnormalities in dilated cardiomyopathy. They reviewed 303 consecutive and extensively phenotype dilated cardiomyopathy patients who underwent cardiac imaging, Holter monitoring, and endomyocardial biopsy and in turn also underwent DNA sequencing of 47 cardiomyopathy associated genes. 13% of these patients had Titin abnormalities. Over long-term followup they noted that these patients had increased ventricular arrhythmias compared to other types of dilated cardiomyopathy, but interestingly, they had similar survival rates. Arrhythmias in those Titin abnormal patients were most prominent in those who were subjected to an additional environmental trigger, including viral infection, cardiac inflammation, other systemic disease or toxic exposure. They also noted the cardiac mass was relatively reduced in titan admirable patients.                                                 They felt that all components of the mitochondrial electron transport chain we're simply up-regulated in Titin abnormal patients during RNA sequencing and interstitial fibrosis was also augmented. As a result, they concluded that Titin variant associated dilated cardiomyopathy was associated with an increased risk of ventricular arrhythmias, and also with more interstitial fibrosis. For a long time we have reviewed all non ischemic cardiomyopathy as essentially equal. However, more recent data has suggested that we can actually hone in on the cause. In turn, if we hone in on the cause, we might be able to understand the effects of specific therapies for ventricular arrhythmias based on that underlying cause. Patchy fibrosis might not be as amenable, for example, to ablation as discreet substrate that we might see in infarct related VT. Understanding the relative benefit in very specific types of myopathies might hold benefit in understanding how to, one, risk stratify these patients, and two, understand what type of therapy, whether pharmacologic or ablative, might result in greatest benefit to the patients.                                                 Changing gears entirely now to the role of genetics, we review multiple articles in various genetic syndromes published this past month. First, we reviewed an article by Providência et al. published in the last month's issue of heart entitled 'Impact of QTc formulae in the prevalence of short corrected QT interval and impact on probability and diagnosis of short QT syndrome.' The authors sought to assess the overall prevalence of short corrected QT intervals and the impact on diagnosis of short QT syndrome using different methods for correcting the QT interval. In this observational study they reviewed the sudden cardiac death screening of risk factors cohorts. They then applied multiple different correction formulae to the ECGs. They noted that the prevalence of individuals with the QTc less than 330 and 320 was extremely low, namely less than .07 and .02% respectively. They were also more frequently identified using the Framingham correction. The different QTc correction formulae could lead to a shift of anywhere from 5 to 10% of individuals in the cohort overall.                                                 They further noted, that based on consensus criteria, instead of 12 individuals diagnosed with short gut syndrome using the Bazett equation, a different number of individuals would have met diagnostic criteria with other formulae, 11 using Fridericia, 9 with Hodges, and 16 using the Framingham equation. Thus, they noted that overall the prevalence of short QT syndrome exceedingly low and an apparently healthy adult population. However, reclassification as meeting criteria might be heavily dependent on which QT correction formula is used. The importance of these findings is that not all QTs are created equal.                                                 Depending on how you compute the QT interval in which formula to use may affect how you actually risk characterize a patient. Unfortunately, these data do not necessarily tell us which is the right formula, but this highlights that it might be relevant to in the future evaluate the role of different formulae and identifying which is the most necessary to classify a patient.                                                 Moving on to an article published in last month's issue of the journal of clinical investigation by Chai et al. we review an article entitled 'Physiological genomics identifies genetic modifiers of Long QT Syndrome type 2 severity.' Congenital Long QT Syndrome is a very well recognized, inherited channelopathy associated life-threatening arrhythmias. LQTS type 2 is specifically caused by mutations in casein to encoding the potassium channel hERG. However, even with the mutation not all patients exhibit the same phenotype. Namely some patients are more at risk of life threatening arrhythmias in spite of having the same mutation as others who do not exhibit the same severity phenotype. The authors sought to evaluate whether specific modifiable factors within the remaining genetic code might be modifying the existing mutation. Thus, they sought to identify contributors to variable expressivity in an LQT 2 family by using induced pluripotent stem cell derived cardiomyocytes and whole exome sequencing in a synergistic manner.                                                 They found that patients with severely effected LQT 2 displayed prolonged action potentials compare to sales from mildly effected first-degree relatives. Furthermore, stem cells derived from patients were different in terms of how much L-type calcium current they exhibited. They noted that whole exome sequencing identified variants of KCNK17 and the GTP-binding protein REM2 in those patients with more severe phenotypes in whom greater L-type calcium current was seen. This suggests that abnormalities or even polymorphisms in other genes might be modifying the risk attributed to by mutations in the primary gene. This showcases the power of combining complimentary physiological and genomic analysis to identify genetic modifiers and potential therapeutic targets of a monogenic disorder. This is extraordinarily critical as we understand on one level that when we sequence a monogenic disorder that there might exist variants of uncertain significance, namely they have not been classified as disease causing, but could be. In turn, we also recognize that mutations in a family might effect different relatives differently. However, why this is has been relatively unclear.                                                 If we can understand and identify those patients who are most at risk of dangerous abnormal rhythms, this will be useful in how much to follow them, and what type of therapy to use in them. The fact that other genes might modify the risk even in the absence of specific mutations, suggests that novel approaches to characterizing the risk might help for the risk modified patients classification in general. Clinical use, however, remains to be seen.                                                 Moving on from long QT, we evaluate 'The Diagnostic Yield of Brugada Syndrome After Sudden Death With Normal Autopsy' noted in last month's issue of the Journal of American College of Cardiology and published by Papadakis et al. It is well known, the negative autopsies are not uncommon in patients, however, families might be wondering how at risk they are. Thus, the authors sought to assess the impact of systematic ajmaline provocation testing using high right precordial leads on the diagnostic yield Brugada syndrome in a large cohort of Sudden Arrhythmic Death syndrome families. Amongst 303 families affected by Sudden Arrhythmic Death Syndrome evaluation was done to determine whether or not there was a genetic inherited channelopathy cause. An inherited cardiac disease was diagnosed in 42% of the families and 22% of relatives Brugada syndrome was the most prevalent diagnosis overall amongst 28% of families. Ajmaline testing was required, however, to unmask the Brugada Syndrome in 97% of diagnosed individuals. Furthermore, they use of high right precordial leads showed a 16% incremental diagnostic yield of ajmaline testing for diagnosing Brugada syndrome.                                                 They further noted that a spontaneous type 1 regard or pattern or a clinically significant rhythmic event developed in 17% of these concealed regardless syndrome patients. The authors concluded the systematic use of ajmaline testing with high right precordial leads increases the yield of Brugada Syndrome testing in Sudden Arrhythmic Death Syndrome families. Furthermore, they noted that assessments should be performed in expert centers or patients could also be counseled appropriately. These findings are important and one of the big questions always becomes how aggressively to test family members of patients or of deceased individuals who experienced sudden arrhythmic death. Many of these patients have negative autopsies, and genetic autopsy might not be possible due to lack of tissue or blood products that can be adequately tested.                                                 The data here suggest that amongst a group of 303 sudden arrhythmic death, families that Brugada Syndrome is by far the most frequent diagnosis. If an inherited cardiac disease was identified. In turn, it is not ECG alone or echo alone that helps identify them, but requires drug provocation testing in addition to different electrode placements. Whether or not this will consistently offer benefit in patients in general or my result in overcalling remains to be seen next within the realm of genetic predisposition.                                                 We view an area where we don't know if there's a genetic predisposition in article published by Tester et al. entitled Cardiac Genetic Predisposition in Sudden Infant Death Syndrome in last month's issue of the journal of american college of cardiology. Sudden Infant Death Syndrome is the leading cause of post-neonatal mortality and genetic heart diseases might underlie some cases of SIDS. Thus the authors sought to determine the spectrum and prevalence of genetic heart disease associated mutations as a potential monogenic basis for Sudden Infant Death Syndrome. They study the largest cohort to date of unrelated SIDS cases, including a total of 419 individuals who underwent whole exome sequencing and targeted analysis for 90 genetic heart disease susceptibility genes. Overall, 12.6% of these cases had at least one potentially informative genetic heart disease associated variants. The yield was higher in those mixed European ancestry than those of European ancestry.                                                 Infants older than four months were more likely to host a potentially informative gene. Furthermore, they noted that only 18 of the 419 SIDS cases hold a [inaudible 01:01:26] or likely pathogenic variant. So in other words, only 4% of cases really had a variant that they could say was distinctly pathogenic or likely pathogenic. Thus, overall, the minority of SIDS cases have potentially informative variant in genetic heart disease susceptibility gene, and these individuals were mostly in the 4 to 12 month age group. Also, only 4% of cases had immediately clinically actionable variance, namely a variant, which is well recognized as pathogenic and where we could actually say that a specific therapy might have had some effect. These findings can have major implications for how best to investigate SIDS cases in families. It might suggest that SIDS cases where the individual was older, nearly 4 to 12 months of age might have a greater yield in terms of identifying variance.                                                 While this might not affect the deceased in fit, it might affect, families are planning on having another child in whom a variant can be identified.                                                 Finally, within the realm of genetics, we review an article published in last month's issue of Science Advances by Huang. et al. entitled 'Mechanisms of KCNQ1 Channel Dysfunction in Long QT Syndrome Involving Voltage Sensor Domain Mutations'. Mutations that induce loss of function of human KCNQ1 underlie the Long QT Syndrome type 1. While hundreds of mutations have been identified the molecular mechanism by which they result in impaired function are not as well understood. The authors sought to investigate impact of 51 specific variants located within the voltage sensor domain and emphasized effect on cell surface expression, protein folding, and structure. For each variant efficiency of trafficking of the plasma membrane, impact of proteasome inhibition, and protein stability were evaluated. They noted that more than half of the loss of function mutations were seen to destabilized structure of the voltage sensor domain, generally accompanied by mistrafficking and degradation by the proteasome.                                                 They also noted that five of the folding defective Long QT Syndrome mutant sites were located in the S0 helix, where they tend to interact with a number of other loss of function mutation sites in other segments of the voltage sensor domain. They suggested these observations reveal a critical role for the S0 helix as a central scaffold to help organize and stabilized KCNQ1 overall. They also note the importance of these findings is that mutation-induced destabilization of membrane proteins may be a more common cause of disease functioning in humans. The importance of these findings lies in better understanding why specific mutations lead to appa

Creatrix extraordinaire Jennifer Sodini stops by Synchronicity to discuss her recent trip to Rhythmia in Costa Rica, cosmic consciousness, the importance of forgiveness and the holy power of love. Check out Evolve and Ascend On the web: http://www.evolveandascend.com/ On Facebook: https://www.facebook.com/evolveandascend/   Support Synchronicity on Patreon so Noah doesn't go insane ----> https://www.patreon.com/synchronicity

Founder of Rhythmia, Gerard Powell, stops by Synchronicity to discuss money, misery and ayahuasca. Full write up available at https://syncpodcast.com/gerard Become a Patron and support Synchronicity today. Perks include access to all the music you hear on the show. Check it out at https://patreon.com/synchronicity