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In this inaugural special live episode of Parola Progetto, recorded at Salotto in Brooklyn and presented in English, we are honored to host Paola Antonelli.As the Senior Curator of the Department of Architecture and Design at The Museum of Modern Art (MoMA) and the museum's Director of Research and Development, Antonelli brings a wealth of experience and insight. During our conversation, we delve into her distinguished career at MoMA, discussing the dynamics of success and rejection, the evolving role of curating, and how museums function as research and development hubs for society. Antonelli offers her perspectives on technology, artificial intelligence, and the future of design, highlighting the critical importance of thoughtful analysis and cultural awareness in these fields.The links of this episode:Salotto, a hub for cultural research and production run by NYC-based Italian creative professionals https://salotto.nycDesign Emergency, curated by Alice Rawsthorn and Paola Antonelli https://www.instagram.com/design.emergencyMoMA R&D Salons http://momarnd.moma.org/salons“Broken Nature: Design Takes on Human Survival”, curated by Paola Antonelli at La Triennale di Milano in 2019 https://triennale.org/en/events/broken-nature “Planet City” by Liam Young https://www.moma.org/collection/works/450744 “Pirouette. Experiments and Turning Points in Design” curated by Paola Antonelli at MoMA in 2025https://www.moma.org/calendar/exhibitions/5756“ITEMS. Is Fashion Modern?”, curated by Paola Antonelli at MoMA in 2018https://www.moma.org/calendar/exhibitions/1638 "The Emperor of All Maladies: A Biography of Cancer" by Siddhartha Mukherjee https://en.wikipedia.org/wiki/The_Emperor_of_All_Maladies
Jessica Hische is a lettering artist and New York Times bestselling author based in Oakland, California. She specializes in typographical work for logos, film, books, and other commercial applications. Her clients include Wes Anderson, The United States Postal Service, Target, Hallmark, and Penguin Books, and her work has been featured in design and illustration annuals both in the U.S. and internationally. She's been named a Print Magazine New Visual Artist (20 under 30), one of Forbes 30 under 30 in Art and Design, an ADC Young Gun, a “Person to Watch” by GD USA, and an Adweek “Creative 100.” In our conversation, we discuss:• My new logo and brand!• Jessica's process for refreshing my logo/brand• Why most startups shouldn't worry about their logo/brand• The psychology behind different typography choices• Balancing creativity with business needs in logo design• Jessica's unique approach to pricing logo work• How AI is (and isn't) impacting the design world• Jessica's other creative pursuits, including children's books and art supply stores—Brought to you by:• The Enterprise Ready Conference — For B2B leaders building enterprise SaaS• OneSchema — Import CSV data 10x faster• Merge — A single API to add hundreds of integrations into your app—Find the transcript at: https://www.lennysnewsletter.com/p/seeing-like-a-designer-jessica-hische—Where to find Jessica Hische:• Threads: https://www.threads.net/@jessicahische• Instagram: https://www.instagram.com/jessicahische• Website: https://jessicahische.is—Where to find Lenny:• Newsletter: https://www.lennysnewsletter.com• X: https://twitter.com/lennysan• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/—In this episode, we cover:(00:00) Jessica's background(01:32) The logo refresh process(09:45) When to refresh your logo(11:45) High-level overview(18:04) Approaching Lenny's brand refresh(24:25) How to see like a designer(37:53) Lenny's new logo: where we landed(44:07) Brand's role in company success(50:04) Jessica's flexible pricing strategies and collaborative design process(57:14) Balancing multiple creative projects(01:01:48) Using AI in creative work(01:05:50) Upcoming projects and final thoughts(01:08:24) Lightning round—Referenced:• Jeni's: https://jenis.com• James Edmondson on LinkedIn: https://www.linkedin.com/in/jamestedmondson/• Figma Config: https://config.figma.com/• Helvetica: https://en.wikipedia.org/wiki/Helvetica• MyFonts: https://www.myfonts.com/• Geometric sans serif fonts: https://www.myfonts.com/pages/tags/geometric%20sans%20serif-fonts• The Rise of Fractional Executives: https://www.reforge.com/blog/leveraging-fractional-executives• JH&F: https://jessicahische.shop/pages/my-oakland-store• Drawling: https://drawling.shop/• Jessica Hische's books on Amazon: https://www.amazon.com/stores/Jessica-Hische/author/B082XDN54V• Dreamforce: https://www.salesforce.com/dreamforce• Bezier handles: https://www.tella.tv/definition/bezier-handles• My First Book of Fancy Letters: https://www.amazon.com/My-First-Book-Fancy-Letters/dp/0593385012/r• The Creative Act: A Way of Being: https://www.amazon.com/Creative-Act-Way-Being/dp/0593652886/• Inside Paragraphs: Typographic Fundamentals: https://www.amazon.com/Inside-Paragraphs-Fundamentals-Cyrus-Highsmith/dp/1616899417• Just Kids: https://www.amazon.com/Just-Kids-Patti-Smith/dp/0060936223• Robert Mapplethorpe: https://en.wikipedia.org/wiki/Robert_Mapplethorpe• The Emperor of All Maladies: A Biography of Cancer: https://www.amazon.com/Emperor-All-Maladies-Biography-Cancer/dp/1439170916/r• Severance on Prime Video: https://www.amazon.com/Severance-Toby-Stephens/dp/B001ARYGCU• Penco brown bag stand: https://penco.jp/en/products/db079/• XOXO: https://xoxofest.com/• Mariame Kaba quotes: https://www.goodreads.com/author/quotes/8156101.Mariame_Kaba—Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.—Lenny may be an investor in the companies discussed. Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe
Chapter 1 What's The Gene Book by Siddhartha MukherjeeThe Gene: An Intimate History is a book written by Siddhartha Mukherjee, an Indian-American physician and writer. Published in 2016, the book explores the history, science, and ethical implications of genes, genetics, and the field of genomics. It delves into various topics such as hereditary diseases, genetic engineering, the role of genes in shaping our identities, and the future of genetic research. The Gene received critical acclaim and was a Pulitzer Prize finalist in the nonfiction category. It is regarded as an engaging and accessible exploration of the complex subject of genetics.Chapter 2 Is The Gene Book A Good BookYes, "The Gene: An Intimate History" by Siddhartha Mukherjee is widely considered to be a good book. It has received positive reviews from both critics and readers alike. The book explores the history and science behind genetics and gene research, delving into the discovery of genes, their impact on human lives, and the ethical implications of genetic manipulation. Mukherjee's writing style is engaging and accessible, making complex scientific concepts easily understandable for the general audience. Overall, "The Gene" is highly recommended for those interested in genetics and its impact on society.Chapter 3 The Gene Book by Siddhartha Mukherjee SummaryThe Gene Book by Siddhartha Mukherjee is a comprehensive exploration of the history, science, and implications of genetics. Throughout the book, Mukherjee delves into the origins of genetics, starting with the discovery of DNA and the early understanding of inheritance.Mukherjee also delves into the revolutionary discoveries made in the field of genetics, such as the mapping of the human genome and the development of techniques to manipulate and edit genes. He explores the ethical and moral questions that arise from these advancements, discussing topics like designer babies, gene therapy, and genetic testing.The book also includes personal anecdotes and stories from Mukherjee's own family, as he has a history of mental illness in his family. He discusses the genetic component of mental illness and the search for genetic markers that can help in diagnosis and treatment.Throughout the book, Mukherjee emphasizes the complexity of genetics and the interplay between genes and environmental factors. He challenges the notion of genetic determinism and highlights the importance of understanding genetics in a broader context.In summary, The Gene Book by Siddhartha Mukherjee is a thought-provoking exploration of the history, science, and ethical considerations surrounding genetics. It provides a comprehensive overview of the field while also delving into personal stories and issues of societal importance. Chapter 4 The Gene Book AuthorSiddhartha Mukherjee is an Indian-American physician, scientist, and writer. He was born on July 21, 1970, in New Delhi, India. Mukherjee is renowned for his book "The Gene: An Intimate History," which was published on May 17, 2016."The Gene: An Intimate History" explores the history, discovery, and implications of the gene, giving insights into its role in heredity, evolution, and human existence. The book received critical acclaim and won several awards, including the 2017 Royal Society Insight Investment Science Book Prize.In addition to "The Gene," Siddhartha Mukherjee has also written a book called "The Emperor of All Maladies: A Biography of Cancer," which was published in 2010. This book chronicles the history of cancer, including its potential causes, treatments, and ongoing
“When I meet with patients, I try and remind them, ‘Yes, you do have these side effects that can happen' and make sure that they're informed, but also try and reassure them that not everyone gets it as severe as maybe the movies and TV shows portray,” Dane Fritzsche, PharmD, BCOP, informatics pharmacist from the Fred Hutchinson Cancer Center at the University of Washington Medicine in Seattle, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a discussion about what oncology nurses need to know about alkylating agents for patients with cancer. This episode is the first in a series about drug classes, which we'll include a link to in the episode notes. You can earn free NCPD contact hours after listening to this episode and completing the evaluation linked below. Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0 Earn 0.75 contact hours of nursing continuing professional development (NCPD), which may be applied to the oncology nursing practice and treatment ILNA categories, by listening to the full recording and completing an evaluation at myoutcomes.ons.org by November 17, 2025. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of NCPD by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: The learner will report an increase in knowledge related to alkylating agents. Episode Notes Complete this evaluation for free NCPD. Oncology Nursing Podcast Episode 242: Oncology Pharmacology 2023: Today's Treatments and Tomorrow's Breakthroughs ONS Voice oncology drug reference sheets Clinical Journal of Oncology Nursing article: Chemoprevention: An Overview of Pharmacologic Agents and Nursing Considerations ONS book: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) ONS Huddle Card: Alkylating Agents The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee ChemoCare drug information Hematology/Oncology Pharmacy Association (HOPA) National Cancer Institute's A to Z List of Cancer Drugs Patient education guides created as a collaboration between ONS, HOPA, NCODA, and the Association of Community Cancer Centers: Oral Chemotherapy Education Sheets IV Cancer Treatment Education Sheets To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast Club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From Today's Episode “Alkylating agents are a very interesting class of chemotherapy agents, both mechanistically as well as historically. I remember back in pharmacy school learning this was actually the first class of medicines used to treat cancer, and it actually starts way back in World War I with the use of sulfur mustard gas, in kind of a military fashion, and then noticing some of the responses that soldiers as well as civilians who were actually exposed to that. They would develop things like bone marrow suppression, as well as other antitumor effects. Sadly, it's rough to see mustard gas as being the first agent to lead to something so remarkable, because it was a weapon of devastation, but it did lead to some breakthroughs.” TS 1:43 “The first thing that jumps to my mind when thinking about alkylating agents is their toxicities and then their supportive care agents that we use to make sure that we're treating our patients well and making their care optimum. So, when I, as an oncology pharmacist, would look at these orders, I immediately am jumping to, are we giving them appropriate antiemetics? Because a lot of these agents are highly emetogenic or moderately emetogenic by NCCN. A lot of them have other organ toxicities, like are really harsh on the kidneys. Are they getting their pre- and post-hydration? And then also many of these agents are very bone marrow suppressing, meaning they're targeting the red blood cells, they're hitting platelets, they're reducing our ANCs and making patients at higher risk for infection, you know, so do we need growth factor support here? Are the patients—their current labs—are they able to take another dose at this time or do we need to dose reduce or delay therapy because their platelets are just too low now?” TS 09:54 “Honestly, it's probably one of the most important things is collaborating together to help provide optimal patient care. And to me, kind of the biggest thing that jumps out is just good communication between the various team members. I can't tell you how many times I would learn crucial information either from an infusion nurse chatting with the patient or walking down the hall or giving a call to one of our lovely clinical nurse coordinators here at Fred Hutch. You know, I always wanted to make sure that I go in and have the full picture of where the patient's at, what, if any, challenges there have been with this patient's particular case, just to make sure that I'm up to date about them and able to provide as good of care as I can.” TS 14:55 “Unfortunately, this class of drugs does come with kind of those generic chemotherapy side effects that we think of: hair loss, nausea and vomiting, and bone marrow suppression. That just comes as a function of how these work. These agents are not selective for just cancer. They're more selective for rapidly dividing cells. So, that leaves our normal cells that rapidly divide like our hair, our GI tract, our bone marrow, you know, to get hit by these.” TS 17:50 “The next thing I always drill my residents on, when I'm teaching them how to provide actionable and helpful information about their regimens that they're getting, is kind of like you're saying, outlining those expectations. How do you prevent these side effects? When do these side effects even start to show up? Like, am I going to immediately be nauseous right when the cisplatin gets turned on? Well, maybe, not super common, but it's more common that we'll see it in, you know, at the end, in the next couple of days and within the next 72 hours or going into the nuances between acute versus chronic nausea and things like that. So, it's really trying to empower the patients with information. How do they prevent this? What are we doing to help prevent it? And then when should they call us? When is the stuff that we're preventing didn't help? When should they call us to get more help?” TS 24:04 “I think that's a misconception that we as healthcare professionals can really help alleviate with our patients, reminding them that, yes, they do carry risks, but we also have a lot of supportive care agents to kind of help minimize that toxicity. And then we have this whole team of professionals behind you to help carry you through the treatment.” TS 29:34
Chapter 1 What's The Emperor of All Maladies"The Emperor of All Maladies: A Biography of Cancer" is a non-fiction book written by Siddhartha Mukherjee, an Indian-American physician and researcher. Published in 2010, the book provides a comprehensive history of cancer, focusing on its origins, treatment methods, and the ongoing battle against the disease. It explores the scientific, social, and personal aspects of cancer, and delves into the stories of patients, researchers, and physicians who have shaped the fight against cancer throughout history. "The Emperor of All Maladies" won the Pulitzer Prize for General Nonfiction in 2011 and has been widely acclaimed for its narrative style and depth of research.Chapter 2 Why is The Emperor of All Maladies Worth ReadThe Emperor of All Maladies by Siddhartha Mukherjee is worth reading for several reasons:1. Comprehensive and engaging storytelling: Mukherjee tells the history of cancer in a captivating and accessible manner. He weaves together personal stories of patients and their struggles with insightful scientific explanations, making the book suitable for both lay readers and those with a scientific background.2. In-depth exploration of a complex disease: Cancer is a multifaceted and elusive disease, and Mukherjee takes the time to explore its many aspects. He discusses its origins, the various treatments developed over the years, the social and political factors surrounding cancer research, and the implications for the future.3. Humanizes the disease: By sharing personal accounts of patients and their experiences, Mukherjee puts a face to the disease. This human perspective helps readers empathize with those affected by cancer and understand the devastating impact it has on their lives.4. Explores the triumphs and failures: The book covers both breakthroughs and setbacks in cancer research, highlighting the perseverance and determination of scientists throughout history. It gives readers a deeper appreciation for the complexities involved in fighting this disease.5. Raises important questions: The Emperor of All Maladies makes readers think about the ethical dilemmas faced by doctors and researchers in the field of cancer. It prompts discussions about the balance between scientific progress and patient welfare, the cost of treatment, and the role of societal attitudes toward cancer.Overall, The Emperor of All Maladies is a thought-provoking and informative book that offers a comprehensive overview of cancer, its history, and the ongoing efforts to understand and combat it.Chapter 3 The Emperor of All Maladies SummaryThe Emperor of All Maladies: A Biography of Cancer is a non-fiction book by Siddhartha Mukherjee published in 2010. The book provides a comprehensive and engaging narrative of the history, biology, and treatment of cancer.Mukherjee begins the book by tracing the origins of cancer, exploring its appearances in ancient civilizations and his own personal encounters with patients as an oncologist. He delves into the roots of cancer research, discussing key breakthroughs such as the discovery of DNA and the first successful treatments of childhood leukemia.The author then navigates through the evolution of cancer treatment, from early surgeries and radiation therapy, to the development of chemotherapy drugs like Methotrexate and Tamoxifen. He also explores the rise of cancer organizations such as the American Cancer Society and the National Cancer Institute, highlighting their impact on research and public awareness.Mukherjee also sheds light on the various challenges and controversies surrounding cancer research and treatment. He discusses the ethical dilemmas faced by...
The double helix of DNA twists in the heart of every human cell, and it comes with some editing software known as epigenetics that power what parts turn on and off and when. Scientists are still still working to understand exactly how genetics and epigenetics work, but we are learning more every day.Nessa Carey is the former International Director at PraxisUnico and the author of several books on genetics. Her latest book is titled Hacking the Code of Life: How gene editing will rewrite our futures.Nessa and Greg discuss how genetics and epigenetics work and are related, with some concrete examples. Nessa discusses how genetics have been used to clone species and cells in laboratories and the differences between other animals and humans. Greg and Nessa talk about the uses and limitations of gene technology and the exciting possibilities of the gene editing technology CRISPR.*unSILOed Podcast is produced by University FM.*Episode Quotes:Not all scientists are the same01:00:39: We have to get better at recognizing that not all scientists are the same. Some are really good problem solvers, some are really good creative thinkers, and it's about finding the right ways to support those people to maximum effect. And we need both. We need the problem solvers as well as the genuinely, deeply creative people. And that is expensive, but on the other hand, you don't get the great breakthroughs. If we only had the problem solvers, all we would have now are better iron lungs for polio. We'd never have a vaccine. But sometimes you need those problem solvers to get other things done as well. So we need to be supporting all different types of research.On the complexity of biology17:27: The reality is biology is very, very complicated. All of those systems need to work. If any of them fall apart, the whole thing falls apart. But we're surprisingly tribal and surprisingly wedded to our own theories. I think in biology, we quite often don't realize we're constantly putting ourselves on Gartner's hype cycle, and everybody gets very invested in whichever bit they like and where it's in the cycle at the time.The beauty and cultural value of funding science01:01:52: It's a mistake to think we should fund science because, eventually, it'll fund us back. We should fund science because it's beautiful. We should fund it because it's a magnificent cultural activity that adds to the wealth of human gorgeousness in the same way that fine arts and great literature do. Stuff shouldn't just be funded because it has an economic imperative. Isn't it just beautiful to understand more about how the world works?Why is epigenetics a notable example of scientific paradigm shifts?14:49: Epigenetics has been a great example of how you get paradigm shifts in scientific fields. You get this situation where there's the prevailing theory, and it survives a lot of onslaughts. But then eventually, it crumbles, and the new theory emerges. So, it's been great both scientifically and in terms of the philosophy of science.Show Links:Recommended Resources:Waddington LandscapeThe Emperor of All Maladies: A Biography of CancerGartner Hype CycleJohn Gurdon and Shinya Yamanaka's WorkAnne Ferguson-SmithGuest Profile:Profile on The Royal SocietyNessa Carey's WebsiteNessa Carey on LinkedInNessa Carey on XHer Work:Hacking the Code of Life: How gene editing will rewrite our futuresThe Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and InheritanceJunk DNA: A Journey Through the Dark Matter of the GenomeHuffington Post Articles
How can we live happier lives? That's today's big question, and my guest is Dr. Marc Schulz, the co-author with Dr. Robert Waldinger of “The Good Life: Lessons From the World's Longest Scientific Study of Happiness” They're the most recent generation of co-directors of the Harvard Study of Adult Development, the longest study of happiness ever conducted. Marc is the Associate Director of the Harvard Study of Adult Development and the Sue Kardus PhD 1971 Chair in Psychology at Bryn Mawr College, where he also directs the data science program. And previously, he chaired the Psychology Department and Clinical Development Psychology PhD program at Bryn Mawr.Now, look, how can we lead happier lives is obviously nuanced, complicated question.But I don't think it'll surprise you that almost 90 years of data from this study has shown that well-nourished relationships inside and outside the home are a major key, if not, the major key to what you might call a happy life. It's not money, it's not work or any of these things -- it's the people we relate to.What can 90 years of comprehensive research teach us about protecting and nourishing our most important relationships in times of radical change? Whether that's about having kids or about climate change, this is the most important thing. -----------Have feedback or questions? Tweet us, or send a message to questions@importantnotimportant.comNew here? Get started with our fan favorite episodes at podcast.importantnotimportant.com.-----------INI Book Club:The Good Life: Lessons From the World's Longest Scientific Study of Happiness by Robert Waldinger and Marc SchulzThe Emperor of All Maladies: A Biography of Cancer by Siddhartha MukherjeeFind all of our guest recommendations at the INI Book Club: https://bookshop.org/lists/important-not-important-book-clubLinks:Connect with Dr. Schulz and keep up with his workWatch Robert Waldinger's Ted TalkFollow us:Subscribe to our newsletter at importantnotimportant.comFollow us on Twitter: twitter.com/ImportantNotImpSubscribe to our YouTube channelFollow Quinn: twitter.com/quinnemmettEdited by
Qué ocurre cuando un founder debe ser despedido por el board? Qué trajo los viajes de negocios de Cristobal y Lucas? Un retiro para emprendedores? No te pierdas este emocionante episodio en el que Lucas Lopatin y Cristóbal Perdomo comparten sus últimas aventuras en el mundo empresarial. Cristóbal visitó el Latam Tech Forum y nos cuenta sus impresiones sobre PayPal Latam, mientras que Lucas participó en un evento Mastermind con algunos de los mejores emprendedores del mundo, y nos revela lo que aprendió en ese viaje. Si buscas consejos y motivación para comenzar la semana este episodio es para ti! __ 1:21 Los últimos viajes de negocios 4:29 Latam Tech Forum 8:26 PayPal en Latam 10:50 The Local 15:02 El P de las acciones 23:25 Mastermind para emprendedores 33:11 Boards y opiniones 40:19 el temor de los Founders a los Boards 45:08 Boards eficientes __ Links Mencionados: The Song of the Cell: An Exploration of Medicine and the New Human https://www.amazon.com/Song-Cell-Exploration-Medicine-Human/dp/1982117354/ref=sxts_entity_rec_bsx_s_def_w00_t_aufl?content-id=amzn1.sym.5dfe0744-8339-45c6-96a9-57dc1646b40b%3Aamzn1.sym.5dfe0744-8339-45c6-96a9-57dc1646b40b&cv_ct_cx=siddhartha+mukherjee&keywords=siddhartha+mukherjee&pd_rd_i=1982117354&pd_rd_r=e4309710-f7de-4610-82df-369cf2b02866&pd_rd_w=CxbBk&pd_rd_wg=Gf8gl&pf_rd_p=5dfe0744-8339-45c6-96a9-57dc1646b40b&pf_rd_r=31R79Q2K58NA0T4EJPEF&qid=1683325710&sbo=RZvfv%2F%2FHxDF%2BO5021pAnSA%3D%3D&sr=1-1-7fa08180-4dd8-4dbc-855e-e1a63c54b7ca The Gene: An Intimate History https://www.amazon.com/Gene-Intimate-History-Siddhartha-Mukherjee/dp/147673352X/ref=sxts_entity_rec_bsx_s_def_w00_t_aufl?content-id=amzn1.sym.5dfe0744-8339-45c6-96a9-57dc1646b40b%3Aamzn1.sym.5dfe0744-8339-45c6-96a9-57dc1646b40b&cv_ct_cx=siddhartha+mukherjee&keywords=siddhartha+mukherjee&pd_rd_i=147673352X&pd_rd_r=e4309710-f7de-4610-82df-369cf2b02866&pd_rd_w=CxbBk&pd_rd_wg=Gf8gl&pf_rd_p=5dfe0744-8339-45c6-96a9-57dc1646b40b&pf_rd_r=31R79Q2K58NA0T4EJPEF&qid=1683325710&sbo=RZvfv%2F%2FHxDF%2BO5021pAnSA%3D%3D&sr=1-3-7fa08180-4dd8-4dbc-855e-e1a63c54b7ca The Emperor of All Maladies: A Biography of Cancer https://www.amazon.com/Emperor-All-Maladies-Biography-Cancer/dp/1439170916/ref=sxts_entity_rec_bsx_s_def_w00_t_aufl?content-id=amzn1.sym.5dfe0744-8339-45c6-96a9-57dc1646b40b%3Aamzn1.sym.5dfe0744-8339-45c6-96a9-57dc1646b40b&cv_ct_cx=siddhartha+mukherjee&keywords=siddhartha+mukherjee&pd_rd_i=1439170916&pd_rd_r=e4309710-f7de-4610-82df-369cf2b02866&pd_rd_w=CxbBk&pd_rd_wg=Gf8gl&pf_rd_p=5dfe0744-8339-45c6-96a9-57dc1646b40b&pf_rd_r=31R79Q2K58NA0T4EJPEF&qid=1683325710&sbo=RZvfv%2F%2FHxDF%2BO5021pAnSA%3D%3D&sr=1-2-7fa08180-4dd8-4dbc-855e-e1a63c54b7ca World-Class Assistant https://yourworldclassassistant.com/ Startup Boards: Getting the Most Out of Your Board of Directors https://www.amazon.com/Startup-Boards-Getting-Board-Directors/dp/1118443667 __ Conocé a Bosco Soler! Sitio Web Podcast Twitter Instagram LinkedIn Tenes alguna pregunta? Escribinos y seguinos en: Twitter: @CristobaPerdomo y @llopatin Linkedin: Lucas Lopatin y Cristobal Perdomo y Visitá: Indie Build Wollef --- Send in a voice message: https://podcasters.spotify.com/pod/show/indie-vs-unicornio/message
Siddhartha Mukherjee is an oncologist, professor, researcher, and biotech entrepreneur. He's also a writer, and a fine one at that. His first book, “The Emperor of All Maladies: A Biography of Cancer,” won a Pulitzer Prize. His second, “The Gene: An Intimate History,” shot to the top of the New York Times bestseller list and was made into a documentary by Ken Burns. In his latest book, “The Song of the Cell: An Exploration of Medicine and the New Human,” he says our radical new ability to manipulate cells is changing how we treat everything from Alzheimer's to cancer. --- We launched a new podcast! It's called The Next Big Idea Daily. Follow it now on Spotify or Apple Podcasts or wherever you listen.
Remember when Juul was a verb? The generecized word for vape? I REMEMBER! That business really came and went like a beautiful comet. Joining me to talk about the historic rise and fall of Juul is my dear friend Emma Day! The legal machinations behind regulating cigarettes is FASCINATING, and the status of cigarettes in the law affects the ways we make e-cigs. Also, we just talk about the smoking cessation industry in general, which is a hilarious thing we invented to solve the problem of overproducing unbelievably addictive yet dangerous objects. Emma is so fucking funny, please listen to her podcast Do You Have a Sec? everywhere! SOURCES: Books: The Cigarette: A Political History, Sarah Milov, 2019 The Emperor of All Maladies: A Biography of Cancer, Siddhartha Mukherjee, 2010 Golden Holocaust: Origins of the Cigarette Catastrophe and the Case for Abolition, Robert Proctor, 2011 Web: https://cdn.arstechnica.net/wp-content/uploads/2020/02/MassvsJuul.pdf https://www.fda.gov/news-events/fda-voices/how-fda-regulating-e-cigarettes https://www.nature.com/articles/d41586-019-02991-w https://www.reuters.com/article/us-health-vaping-juul/juul-use-more-than-doubled-among-u-s-teens-young-adults-in-one-year-idUSKBN1ZK2SV https://www.bloomberg.com/news/articles/2022-12-09/juul-to-pay-1-2-billion-in-youth-vaping-settlement https://www.grandviewresearch.com/industry-analysis/nicotine-replacement-therapy-market https://www.reuters.com/legal/litigation/juul-appeals-block-fda-ban-e-cigarettes-2022-06-24/ PS, I'm nominated for a Chicago Reader Award! Vote for me at this link (under "city life" for "best podcast") https://chicagoreader.com/best-of-chicago/2022-ballot-voting-nominations/#/gallery/357091644/
The Twenty Minute VC: Venture Capital | Startup Funding | The Pitch
Cathie Wood is the CEO & CIO @ ARK Invest, focusing solely on disruptive innovation, primarily in the public equity markets. ARK has become renowned for opening up its research and becoming a ‘sharing economy' company in the asset management space. Prior to ARK, Cathie spent twelve years at AllianceBernstein as CIO of Global Thematic Strategies where she managed over $5 billion. Cathie joined Alliance Capital from Tupelo Capital Management, a hedge fund she co-founded, which managed $800 million in global thematic strategies. Prior to Tupelo Capital, she worked for 18 years with Jennison Associates LLC as Chief Economist, Portfolio Manager and Director. In Today's Episode with Cathie Wood We Discuss: 1.) Entry into Hedge Funds at 20: How did Cathie get her first role in the world of finance at the tender age of 20? What is Cathie running from? What is Cathie running towards? What are some of Cathie's biggest lessons from seeing the dot com bust at Tupelo? What does Cathie know now that she wishes she had known when she started investing? 2.) Why Benchmarks and Passive Investing are Bad: Why does Cathie believe that benchmarks and indexes have become dangerous for consumers? Why does Cathie not believe what everyone else does regarding inflation? How much of the performance of large-cap tech stocks is tied to the growth of passive investing? Why does Cathie think the Fed is making a huge mistake? 3.) Time to Pick Companies: Why does Cathie believe that Facebook is emerging as an attractive value stock? How does Cathie believe Elon Musk and Jack Dorsey could build the largest universal wallet? If Cathie were to put all her money into one of their companies, what would it be? Why does Cathie believe Zoom is one of the most misunderstood companies? 4.) Why Venture: Why Now: Why did Cathie decide to do a venture fund with ARK now? Why did Cathie decide to do a no-carry structure with a higher management fee? How does that align incentives with investors? In venture, the asset chooses the capital, how does Cathie analyze why the best founders in the world will pick and work with ARK over other amazing VCs? What is the single biggest risk you are underwriting when investing in ARK's venture fund? Items Mentioned in Today's Episode: Cathie's Favourite Book: The Emperor of All Maladies: A Biography of Cancer
“People write medical histories, people write personal case histories, I didn't want to do either. People write memoirs; I wanted to do all of them in the same book. And I wanted to do that without blurring the boundaries between any and all of those… I consider those parts of living history.” Siddhartha Mukherjee is an oncologist, a professor, a bestselling author and a winner of the Pulitzer Prize for his first book, Emperor of All Maladies: A Biography of Cancer. He joins us on the show to talk about his latest book, The Song of the Cell: An Exploration of Medicine and the New Human, along with gene therapies, balancing the future of science with current patient care, the excitement that comes with scientific discovery, his literary influences and much more with Poured Over's host, Miwa Messer. Featured Books (Episode): The Song of the Cell by Siddhartha Mukherjee The Gene by Siddhartha Mukherjee The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee Featured Books (TBR Topoff): Mountains Beyond Mountains by Tracy Kidder The Facemaker by Lindsey Fitzharris Poured Over is produced and hosted by Miwa Messer and mixed by Harry Liang. Follow us here for new episodes Tuesdays and Thursdays (with occasional Saturdays).
In this episode, Xavier Bonilla has a dialogue with Siddhartha Mukherjee about cellular biology. They define what a cell is and talk about the importance of Leeuwenhoek and Hooke in observing and discovering the cell. They talk about the five basic principles of cell biology and explore the anatomy of a cell. They explain how important B cells and T cells are for the innate immune system and the adaptive immune system for fighting diseases such as SARS-CoV-2 and HIV. They also talk about the potential of stem cells for human medicine and many other topics. Siddhartha Mukherjee is an assistant professor of medicine at Columbia University and a cancer researcher and physician. He has his Bachelors in biology from Stanford University. As a Rhodes Scholar, he has a DPhil in immunology from Oxford University and an MD from Harvard University. He has published articles in journals such as Nature and The New England Journal of Medicine and in mainstream outlets such as The New York Times. He is the author of the 2011 Pulitzer Prize winning, The Emperor of All Maladies: A Biography of Cancer, The New York Times best-Seller, The Gene: An Intimate History, and the author of the new book, The Song of The Cell: An Exploration of Medicine and The New Human. You can find his work here. Twitter: @drsidmukherjee
For the next few months, we're sharing some of our favorite conversations from the podcast's archives. This week's segments first appeared in 2016 and 2018, respectively.Since winning the Pulitzer Prize in general nonfiction for his first book, “The Emperor of All Maladies: A Biography of Cancer,” in 2011, the physician and professor Siddhartha Mukherjee has gone on to write two more sweeping studies of medical and scientific subjects: “The Song of the Cell,” which will be released next week, and “The Gene: An Intimate History,” which came out in 2016. Mukherjee was a guest on the podcast when “The Gene” was published, and he told the host Pamela Paul that his earlier book about cancer had led him naturally to the topic of genetics and heredity. “The more I thought about disease, illness, the more I came back to the question of inheritance: What do we inherit, what do our families give to us? How much of it is genetic, how much of it is environmental?” he said.Also this week, we revisit Kate Atkinson's podcast appearance from 2018, when she discussed her World War II spy novel “Transcription” and its heroine, who starts out as “a very clever girl who's slightly out of order.” Atkinson's latest novel, “Shrines of Gaiety,” was published last month.We would love to hear your thoughts about this episode, and about the Book Review's podcast in general. You can send them to books@nytimes.com.
The medical field is a multi trillion dollar industry. In 2020 the U.S healthcare spending increased by 9.7 percent, reaching 4.1 trillion dollars. That averages out to be about $12,530 per person. With profits like that to be made, is it out of the realm of possibilities that there are cures for diseases that are being withheld? When you realize that almost 50% of people will face some type of cancer in their lifetime, the theory doesn't seem so far-fetched. EVERYTHING TRUE CRIME GUYS: https://linktr.ee/Truecrimeguysproductions Patreon.com/truecrimeguys Merch: truecrimeguys.threadless.com Sources: The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee https://www.hsph.harvard.edu/magazine/magazine_article/the-cancer-miracle-isnt-a-cure-its-prevention/ https://www.worldwidecancerresearch.org/news-opinion/2020/march/could-somebody-be-hiding-the-cure-for-cancer/ https://www.burzynskiclinic.com https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/cancer/art-20046762 https://www.cancer.gov/about-cancer/treatment https://youtu.be/Bl_5PZBXgc0 https://youtu.be/CxD7sFRIju0 https://youtu.be/DP7fFoKPWcM https://youtu.be/h2rR77VsF5c https://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-and-Reports/NationalHealthExpendData/NationalHealthAccountsHistorical https://youtu.be/OVrd1hWVpls
Our guest Ellen Albertson is a psychologist and self-compassion teacher living in the Champlain Islands of Vermont. She brings over 25 years of counseling, coaching, and healing experience to her holistic practice and transformational work. As an author and radio host, she's known as The Midlife Whisperer™, helping women raise their vibration so they have the energy, confidence, and clarity to make their next chapter their best chapter. When we spoke, Ellen had just spent the morning in her garden picking a bouquet for the radiation room and she zoomed off to treatment after we hung up. It's rare to be invited into someone's process when everything is still so raw. Wherever you are in your journey, I hope you find this candid conversation to be good company. Ellen's Resource List You Can Heal Your Life by Louise Hay The Art of Living: Peace and Freedom in the Here and Now Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee Documentary: Fantastic Fungi Radical Remission and Radical Hope by Kelly Turner Anticancer Living by Lorenzo Cohen The Cancer Revolution by Leigh Erin Connealy The Metabolic Approach to Cancer by Dr. Nasha Winters
We don't often look at preventative measures when it comes to our health. We typically look for ways to get better after we get sick — take a pill or undergo this operation, and everything will be better! Don't put off becoming more health-conscious until you've been diagnosed with a disease like cancer. The adage still holds: prevention is better than a cure. In this episode, Best Selling Science Author++ Travis Christofferson discusses the root causes of diseases and how we can take a preventive approach to health. He shares emerging cancer treatment research and encourages us to learn more about them. Focus on your overall health rather than specific diseases. When your body has a good immune system, it can help prevent illnesses like cancer! If you want to learn more about the latest in cancer research disease prevention, then this episode is for you! Here are three reasons why you should listen to the full episode: Understand the root causes of diseases and how we can prevent them rather than waiting for illness. Learn about emerging cancer treatment research, including the metabolic approach, ketosis, abscopal effect, etc. The state of our health care systems Get Customised Guidance for Your Genetic Make-Up For our epigenetics health programme, all about optimising your fitness, lifestyle, nutrition and mind performance to your particular genes, go to https://www.lisatamati.com/page/epigenetics-and-health-coaching/. Customised Online Coaching for Runners CUSTOMISED RUN COACHING PLANS — How to Run Faster, Be Stronger, Run Longer Without Burnout & Injuries Have you struggled to fit in training in your busy life? Maybe you don't know where to start, or perhaps you have done a few races but keep having motivation or injury troubles? Do you want to beat last year's time or finish at the front of the pack? Want to run your first 5-km or run a 100-miler? Do you want a holistic programme that is personalised & customised to your ability, goals, and lifestyle? Go to www.runninghotcoaching.com for our online run training coaching. Health Optimisation and Life Coaching Are you struggling with a health issue and not getting anywhere with the traditional medical system and need people who look outside the square who are up on the cutting edge of research and are connected to some of the greatest science and health minds in the world? Then reach out to us at lisa@lisatamati.com, we can jump on a call to see if we are a good fit for you. Mindset and Mental Toughness coaching. If you have a big challenge ahead, are dealing with adversity or want to take your performance to the next level and want to learn how to increase your mental toughness, emotional resilience, foundational health, and more, contact us at lisa@lisatamati.com. Order My Books My latest book Relentless chronicles the inspiring journey about how my mother and I defied the odds after an aneurysm left my mum Isobel with massive brain damage at age 74. The medical professionals told me there was absolutely no hope of any quality of life again. Still, I used every mindset tool, years of research and incredible tenacity to prove them wrong and bring my mother back to full health within three years. Get your copy here: https://shop.lisatamati.com/collections/books/products/relentless. For my other two best-selling books Running Hot and Running to Extremes, chronicling my ultrarunning adventures and expeditions all around the world, go to https://shop.lisatamati.com/collections/books. 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The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Ketone Products by Keto-Pro Exogenous Ketones developed by Nutritionist and Body Building champion Richard Smith. Keto-Pro BHB Exogenous Ketones – 250g MORE BHB per gram than other MARKET LEADERS. During In-house testing, Keto-Pro BHB raised ketones quicker, higher and for longer than other market leaders. Ketones My ‘Fierce' Sports Jewellery Collection For my gorgeous and inspiring sports jewellery collection, 'Fierce', go to https://shop.lisatamati.com/collections/lisa-tamati-bespoke-jewellery-collection. Episode Highlights [03:17] Travis' Background Travis has an undergraduate degree in biochemistry. He eventually took over the family business and got married. He then finished his master's degree, focusing on cancer metabolism for his independent study. The prevailing teaching during that time was that somatic mutations cause cancer. Travis was inspired by the book, Cancer as a Metabolic Disease, to do a thesis on metabolic theory. Otto Warburg proposed the metabolic theory many years ago, but the medical community dismissed it as simplistic. New evidence reignited interest in the approach. [08:10] The State of Healthcare Public and health institutions have long accepted the somatic approach to cancer, with billions of dollars backing it. The United States spends the most per capita on health care expenditure among developed countries yet has the lowest life expectancy. The issue with the healthcare system lies in variations of treatment, over-treatment, and drug development process. The healthcare industry is focused more on treating diseases rather than preventing them. Although technology has advanced to assist people in tracking their health, people's health is deteriorating. Even if people live longer, they often experience illness and disability in their final years. [12:48] Changing the Healthcare Industry The healthcare incentive structure must change. Doctors get paid for every drug and procedure they prescribe, leading to overtreatment. There are emerging practices where doctors get a big bonus per patient who doesn't need procedures, encouraging them to keep patients in good health. When blood sugar levels rise, doctors usually diagnose diabetes. However, we can test for fasting insulin regularly to intervene. This test can also help people prevent other diseases and become more health-conscious. Change takes time with systems and industries, but we can take simple lifestyle interventions now. [16:01] Why People Are Getting Sicker Maintaining our health can be challenging. We've been conditioned that taking a magic pill is preferable to putting in the effort. Remember that metabolic dysregulation causes aging, not the other way around. In the last 10,000 years, humanity has drastically shifted to consuming processed foods, carbohydrates, and oils, resulting in noticeable consequences. People have also become sedentary. A hunter-gatherer society has no obesity, insulin resistance, or chronic systemic inflammation. However, we frequently see this in the Western world. [20:32] The Root of Diseases Understanding cellular health and inflammatory processes are critical in keeping yourself healthy. Periods of food scarcity have happened throughout humanity's evolution. Our bodies enter ketosis due to the caloric deficit but most never reach this state. Studies have shown that ketosis can help prevent diseases ranging from Alzheimer's to Parkinson's to cancer and diabetes. Constantly eating keeps our immune system active and prevents it from resting, which has implications for chronic inflammatory diseases. [24:53] What Happens During Ketosis? Ketosis happens in a fasted state, and a ketogenic diet is nutritional maintenance. When we fast, our bodies will mobilise the fat we have in our bodies and begin a process of beta-oxidation to burn off fat. A caloric deficit makes this process faster, converting fats into ketone bodies, which then take the place of glucose. Ketones have more thermodynamic energy and ATP per carbon unit compared to glucose. Ketosis also boosts antioxidant levels. Since diseases are oxidative, ketosis can help to combat illnesses. Listen to the episode to learn more! [32:01] Growing Healthcare Trends Research has shown that fasting before chemotherapy can reduce some radiation side effects Sugar is fuel for cancer cells, but doctors continue giving and allowing patients to consume it. There's more awareness of the latest research. The annual Metabolic Therapeutic Conference has grown to around 1600 attendees. When we approach doctors, we will receive information their institution has taught and allowed them to give us. Even with COVID-19, people have yet to explore treatments like monoclonal antibodies, hyperbaric, and Vitamin C. [44:00] The Abscopal Effect on Cancer The abscopal effect is when you target a single tumour site, but it affects other tumour sites in the body. Travis shares a case where someone with breast cancer on a checkpoint inhibitor received a much lower radiation dose. In that case, radiation was sufficient to systematically stimulate the immune system to attack cancer, improving the patient's chances of survival. [47:41] Advancements in Immunotherapy Using peptides to manipulate the immune system is still a trial and error process. The immune system's job is to survey for cancer, get rid of it early, and create a checkpoint to avoid attacking itself. [49:44] Emerging Cancer Treatment Research In detection, metastasis is an early stage event rather than a late-stage one. Cancer cells break off, dying when it reaches the bloodstream. This selection pressure creates different genetic mutations in tumours. The somatic mutation theory argues that a series of sequential mutations cause cancer, with each tumour site having a unique set of driving mutations. The epigenetic metabolic theory posits that these mutations are a side effect of the disease. All cancers burn sugar and evade the immune system, but mutations vary too much. Treatments should focus on epigenetic expression rather than mutations. [55:16] Researching Treatment Options The medical field is filled with uncertainty. Cancer treatment options have not been compared. After an in-depth look at clinical trials, we find that what seems to be the best treatment paradigm isn't always the right option. When conducting research, consider the data and evaluate it using a risk-reward framework. You can choose from low-risk alternatives. [59:59] The Soil Approach to Cancer Cancer grows in the presence of a favourable microenvironment and molecular events. It takes a long time for a chronic irritant to develop cancer cells. Cancer cells take on characteristics of our earliest genes, including replication and the appearance of early embryos. You can help your cells "behave" by providing oxygen and avoiding chronic irritants. Nurture the microenvironment through exercising and eating the right foods. Instead of focusing on the seed or cancer, we should concentrate on the soil or microenvironment. [1:04:05] Health and Longevity While we don't know humankind's natural and optimal states, ketosis and fasting provide a glimpse. Cells stop metabolising as we age, causing inflammation. We may be able to extend life spans if we can reduce senescent cells. Travis shares a study in which mice received fisetin, found in strawberries, reducing senescent cells and prolonging their life. There's a lot of new research on substances that kill senescent cells, like senolytics, quercetin, and other compounds. [1:08:49] About StageZero Life Sciences StageZero Life Sciences looks into markers of inflammation, insulin resistance, etc. They also recommend potential lifestyle interventions to change those markers. They are currently available in Richmond, Virginia, Toronto, and Ontario, Canada. 7 Powerful Quotes 'It's just a combination of probably a terrible diet and just not moving enough because we were designed to go out and have to work every day to catch food. That's what we evolved, and when you uncouple your physiology from that environmental niche, you see all kinds of problems' ‘It appears that evolution has built in a powerful signal to that when you're in a caloric deficiency, you switch your metabolism…to something called ketosis where you completely shift what you're burning to these little small molecules that come from fat,' ‘We're terrible at focusing on prevention. We focus on the disease, trying to treat it once it's already manifest, which is an absolutely horrible strategy.' ‘If we look at cancer then as the prime drivers being metabolic and epigenetic, that means that all of those things potentially could be modifiable, right? We don't have to target mutations. We can look for ways to change the way cells are expressing genes and so forth, and metabolising substrates and things like that.' ‘Just mind the microenvironment of your body, which is giving you the right food, exercising. It's designed to do that. Every time you do that, it brings down those inflammatory processes, and so forth.' ‘We tend to think we're in this modern era, but with regard to cancer, we will look back 200 years from now, realise that we were just in the Dark Ages. We're still using radiation which was invented about 110 years ago; chemotherapy was invented around World War II. That's still the mainstay of cancer treatments.' ‘When you really look deep, the two problems really are variation in treatment, over-treatment. The drug development process, I think, is one of the main problems too,' Resources Gain exclusive access and bonuses to Pushing the Limits Podcast by becoming a patron! Want to learn more from Travis? Check out his books: Tripping Over the Truth: How the Metabolic Theory of Cancer is Overturning One of Medicine's Most Entrenched Paradigms Curable: How an Unlikely Group of Radical Innovators is Trying to Transform our Health Care System Ketones, The Fourth Fuel: Warburg to Krebs to Veech, the 250 Year Journey to Find the Fountain of Youth The Origin (and future) of the Ketogenic Diet, co-authored with Dr Dom D'Agostino Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer by Thomas Seyfried Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee The Cancer Code: A Revolutionary New Understanding of a Medical Mystery by Dr Jason Fung Healthy Conversations With Travis Christofferson and Guest, Jason Fung M D from StageZero Life Sciences Check out these previous episodes with Dr Elena Seranova: Episode 238 - Reverse Ageing to Live Longer and Healthier Episode 189 - Understanding Autophagy and Increasing Your Longevity Episode 183 - Sirtuins and NAD Supplements for Longevity Learn more about cancer and health through our previous episodes: The Six Cornerstones for Better Health with Dr Charles Meakin Cancer Revolution: The Metabolic Approach to Cancer with Maggie and Bradley Jones Abscopal effect following radiation monotherapy in breast cancer: A case report Fisetin is a senotherapeutic that extends health and lifespan Short-term fasting accompanying chemotherapy as supportive therapy in gynecological cancer: protocol for a multicenter randomised controlled clinical trial StageZero Life Sciences: Website | AVRT Program Foundation for Metabolic Cancer Therapies Connect with Travis: LinkedIn | Twitter | Facebook About Travis Travis Christofferson is the founder of The Foundation for Metabolic Cancer Therapies and works in Clinical Development at StageZero Life Sciences Ltd. He is also a science author of several books, including Tripping Over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms, Curable: How an Unlikely Group of Radical Innovators Is Trying to Transform Our Health Care System, Ketones, The Fourth Fuel, and co-author of The Origin (and future) of the Ketogenic Diet. Want to learn more about Travis' work? Check out Foundation for Metabolic Cancer Therapies. You can also connect with him on LinkedIn, Twitter, and Facebook.
Welcome back to WellSeekers as we continue our five part series focusing on cancer. In this series, we'll share inspiring and powerful conversations full of encouragement, hope, wisdom, touching personal stories, and most importantly real world solutions; all from a holistic perspective. We'll talk with professionals and friends of the show on what it's like to hear those words “you have cancer”, real life and practical wisdom and solutions for supporting those diagnosed and living with cancer, support for caregivers, and their heroic kind and self-less acts. So join us on this extraordinary series as we want to help you grow and thrive in the face of a cancer diagnosis if you've been diagnosed with cancer, are living with cancer, know someone dear to you with cancer, or want to prevent this fast growing, deadly and sometimes chronic disease.Today, we welcome Sarah Kown, a medical physicist and radiation oncology therapist and the Founder and CEO of Own Your Cancer Coaching. Sarah offers some great and practical advice on where to start, what to ask, what to know, and what to be mindful of. And we talk about how a cancer coach can help support you and your loved ones navigate a cancer diagnosis and cancer treatment. Along with personalized coaching services, Sarah also developed a new online course, and additional resources for cancer care for you and your loved ones to help support you on your cancer journeys and beyond. So join us today on WellSeekers with Lucia, as we're talking with Sarah on how to support those who have been diagnosed with cancer, those living with cancer, and caregivers alike!To learn more about Sarah and her company, visit her website at ownyourcancercoaching.comBe sure to check put and follow Sarah on IG @cancerspecialistRecommended books in this show:Six Months to Live . . . : Three Guys on the Ultimate Quest for a Miracle Six Month to Live by Arthur BoyleRadical Remission by Kelly TurnerEmperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee----------------WellSeekers with Lucia is a podcast exploring how to find your own story of well from the mind down focusing on holistic mental and emotional health, relationships, and wellness topics.Lucia Nazzaro, MA, MSW, LCSW, is an Emmy nominated multi-media storyteller, professor and expert. She works to create ways to help individuals & society find their story of well with a special focus on how we can rise and comeback from life transitions (both considered positive and negative), relationship issues, and issues that surround the human condition and ways to thrive in the face of adversity and challenge.
It was an honor to have Dr. Natasha Winters on the show. She came highly recommended by our former guest Alison Gannett whose body is right now healing from brain cancer. Dr. Winters is the author of The Metabolic Approach to Cancer: Integrating Deep Nutrition, the Ketogenic Diet, and Nontoxic Bio-Individualized Therapies If you haven't had a chance to hear that show I'll put it in the show notes below. It's really good and her story is eye opening. In that show Alison really sung the praises of Dr. Natasha Winters who has helped turn her life around with regards to the brain cancer her body has. I pose the question in the title of this podcast, can we find the cure for cancer if we constantly are "fighting" it. I even see shirts now that say Fu#$ Cancer. Dr. Winters in my humble opinion (after listening to thousands of hours of alternative health lectures, watching videos, attending seminars, reading books, reading articles and interviewing 500 people myself) that her approach to cancer is one of the best I've seen. I've been in this field since 2003 and have consumed everything I could get my hands on and Dr. Winters really does seem to tackle all the angles when it comes to cancer. It's not enough to focus on the emotional spiritual and still eat a diet that doesn't support healing. It's also not enough to completely neglect the role of emotional and spiritual issues while only focusing on the physical. All parts play a role in my opinion. It takes grit to deal with emotional, spiritual, physical and mental issues when you want your body to heal. I watched many videos of hers before the show to prep but the one below was the one I found most touching and inspiring. Make sure to check it out. On Last Thing! As always your support via your donations and bookmarking our Amazon link to use each time you purchase is how we keep our show going. Thank you for bookmarking our Amazon link even if you're not buying anything right now! :) Sponsor For This Episode: Extreme Health Academy IMRS PEMF Healing Mat Rapid Release Technology Pro 2 The Relax Sauna Bellicon Rebounders Daily Qigong Course Products Related To This Episode: Living Libations Squatty Potty Berkey Water Filters Surthrival Sol CBD BARF World Raw Dog Food Biomat Chemical Free Organic Skincare! Activation Products - Ocean's Alive & Magnesium Show Notes Show with Alison Gannett on cancer Dr. Amen Dr. Hamer Bernie Siegel The Emperor of All Maladies: A Biography of Cancer Haelan 951 Keto brain cancer feeding on fat Biofocus RGCC Greek Cancer Test Biocepts.com Foundation one chemo sensitivity The Real Dangers of Electronic Devices and EMFs - Dr. Joseph Mercola Folks, This Ain't Normal: A Farmer's Advice for Happier Hens, Healthier People, and a Better World Dr. Thomas Seyfried keto Dr. Adrienne C. Scheck keto and cancer Navarro test remissionnutrition.com Listen to other shows with this guest. Show Guest: Dr. Natasha Winters Guest Info: Dr. Nasha Winters, ND, FABNO, L.Ac, Dipl.OM is the visionary and CEO as well as best selling author, lecturer, and the primary consultant of Optimal TerrainTM. Informed by more than 25 years of experience in the health care industry and a thought leader in personalized precision medicine, Dr. Nasha works to educate clients, doctors and researchers world wide on how to apply integrative oncology philosophically and therapeutically. Show Topic: Cancer and the ketogenic diet Guest Website(s): http://optimalterrainconsulting.com/ Social Websites: https://www.facebook.com/optimalterrain/ https://www.facebook.com/drnashawinters Guest Product(s): The Metabolic Approach to Cancer: Integrating Deep Nutrition, the Ketogenic Diet, and Nontoxic Bio-Individualized Therapies Consider Supporting Us: (Opens in a new window - Every bit helps us to keep delivering even better shows that help you heal & thrive!
Why medical students are advised - if you hear hoofbeats behind you, don't expect to see a zebra. In his guide to thinking better, Professor Steven Pinker explores Bayesian reasoning. Steven is joined by Talithia Williams, professor of mathematics at Harvey Mudd College and author of ‘Power in Numbers The Rebel Women of Mathematics', and by Siddartha Mukherjee, professor of medicine at Columbia University and the author of the Pulitzer Prise winning ‘The Emperor of All Maladies A Biography of Cancer' Together they'll help you evaluate ideas, recalibrate your credences and maybe even think a little better. Producers: Imogen Walford and Joe Kent Editor: Emma Rippon Think with Pinker is produced in partnership with The Open University.
In this series, PathPod gathers pathologists Around The Scope to discuss their work in depth. Today, we hear about the History of Pathology. Our host, Dr. Sara Jiang (@Sara_Jiang) speaks with Dr. Marie Christine, Aubry, current president of the History of Pathology Society, Dr. Jim Wright, a professor of Pathology and Laboratory Medicine and Pediatrics at the University of Calgary, Dr. Susan Lester, pathologist at Brigham and Women's Hospital, Dr. Santo Nicosia, emeritus professor of pathology at the University of South Florida in Tampa, and Dr. Julie Lemmon, a private practice pathologist and a student in the history of medicine program through Hopkins. How are medical museums related to medical education? What are the ethical challenges with anatomical collections? How does 3D printing relate to Phineas Gage? Do you know of a medical collection somewhere? Reach out to us! History of pathology society: https://hps.wisc.edu/ Twitter: @Histpathsoc Recommended books and articles: Guiding the Surgeon's Hand, by Juan Rosai: https://books.google.com/books/about/Guiding_the_Surgeon_s_Hand.html Dorothy in a Man's World, by Peter Dawson: https://www.amazon.com/Dorothy-Mans-World-Victorian-Physicians/dp/1523749032 Bathsheba's Breast, by James Olson: https://jhupbooks.press.jhu.edu/title/bathshebas-breast The Emperor of All Maladies: A Biography of Cancer, by Siddhartha Mukherjee: https://en.wikipedia.org/wiki/The_Emperor_of_All_Maladies The Great Influenza, by John Barry: https://www.penguinrandomhouse.com/books/288950/the-great-influenza-by-john-m-barry/ Roses and Rosettes-the two sides of James Homer Wright, by Jim Wright: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155993/ The Radicalization of Breast Cancer Surgery: Joseph Colt Bloodgood's Role in William Stewart Halsted's Legacy,, by Jim Wright: https://pubmed.ncbi.nlm.nih.gov/29681553/
We continue our discussion on breast cancer and this time we talk extensively about the history and science of cancer treatment. Using Akwi's and Gwendolyn's cases, Dr Foma explains treatment procedures and medications used for different kinds of cancer. We talk about the healthcare system in Cameroon, where Dr. Foma started practice. Akwi and Gwendolyn present their different non-profit organizations that work with cancer patients in Cameroon and advocate for cancer awareness. [00:01 - 02:40] Opening segment [02:40 - 08:21] Akwi's Experience with cancer treatment The diagnosis and testing process The steps she had to take before starting treatment The treatment process and reaction to medications [08:31 - 10:33] Discussion on Breast Reconstruction The healthcare factors of breast reconstruction [10:33 - 25:00] Preparing patients for treatment, different cancer medications and their applications Kinds of cancer and treatment methods Different drugs, uses and side effects Comparing and contrasting Gwen and Akwi's cancers and treatment processes [25: 01 - 38:22] History of Cancer treatment and myths Evolution of cancer treatment Improvements in chemotherapy Scientific developments in cancer treatment Treatment practices Alternative treatment myths [38:23 - 50:45] Life with and after breast cancer (Akwi's Story) Emotional factors Physical and lifestyle changes [50:46 - 58: 15] Best practices or habits for cancer patients Advice from Dr Foma on how to cope with cancer Dealing with the community Working with medical staff [58:16 - 01: 07: 05] Resources for Cancer patients Available resources Life for cancer patients in Cameroon Cancer and Cameroon's healthcare system [01:07:05 - END] Akwi and Gwendolyn's work with cancer patients in Cameroon Gwendolyn's Royal Warrior foundation's activities Akwi's Dare to Live with Anjoh foundation Dr Foma's work in Cameroon and suggestions for health administration. Quotable Tweets "My advice usually to those back home overall is that prevention is better than cure. The way Africa is, the way Cameroon is, the way our healthcare system is, prevention is the best tool we have." - Dr Munoh Foma "Sustainability is something we should always think about. All the organizations going to Cameroon should actually have that as part of their mission - whatever advocacy your are going in to provide. If you are providing machines, you want make sure those machines are friendly in the tropical region, you have people who are able to repair them, and also that they are machines you can find replacement parts for." - Dr Munoh Foma "Hospice is one thing we do not have and we are not even welcoming in our society. Fortunately, I am a hospice nurse and I have helped a lot of people transition. We are all going to die but there is nothing better than helping somebody or seeing your family member transition in a more peaceful or pain free way." - Gwendolyn Ngu "When I shared my story I had a couple of women reach out to me from Cameroon to tell me that they were either in treatment or were survivors and it really took me by surprise because back home I knew only of one person that had breast cancer. A lot of young women reach out to me and I tried to get more information about how their treatment process was. It was when I realized I was really lucky to have had to deal with cancer in America and have good insurance; back home, it is a jungle. That is why decided to create the foundation, so I could help." - Akwi Tah Referenced Material: Emperor of All Maladies: A Biography of Cancer You can connect with us on Facebook, Instagram, YouTube, Twitter, or send us an email at hello@livingafricanpodcast.com. Check out our website www.livingafricanpodcast.com for more resources and to learn more. Contact Akwi Tah: Instagram - DARE TO LIVE WITH ANJOH Facebook - Akwi Anjoh Website - www.daretolivewithanjoh.org and via WhatsApp +19802728050. Contact Dr Foma: Dr Foma Munoh Kenne, MD, MPH Richmond University Medical Center for Cancer Care 1000 South Ave. Office Tel: (718) 816-4949 Fmunohkenne@runcsi.org Staten Island, NY, 10314 Contact Gwendolyn Ngu: Facebook: Royal_warriorr Instagram: Royal Warrior Cancer Support Web: www.royalwarrior.org Email: info@royalwarrior.org You can connect with Anyoh on: Facebook (@anyohf), Instagram (@anyohfombad), and Twitter (@anyohfombad).
Lincoln Lau is back on the podcast! Nathan Mallonee interviews Lincoln, who is the director of research at International Care Ministries (ICM) in the Philippines. ICM has been conducting different RCTs in partnership with Innovations for Poverty Action, and Lincoln comes back to talk to us since they published the results of their first RCT and how they're using RCTs today. To find out more about ICM, visit: https://www.caremin.com Book recommendation: Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee
This episode we’re talking about Biology Non-Fiction! We discuss epidemiology, genetics, microbes, kissing, sex, and more! Plus: using physical bookmarks when reading ebooks! You can download the podcast directly, find it on Libsyn, or get it through Apple Podcasts, Stitcher, Google Podcasts, Spotify, or your favourite podcast delivery system. In this episode Anna Ferri | Meghan Whyte | Matthew Murray | RJ Edwards Things We Read (or tried to…) The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee Apollo's Arrow: The Profound and Enduring Impact of Coronavirus on the Way We Live by Nicholas A. Christakis Acquired Traits by Raissa Berg World of Wonders: In Praise of Fireflies, Whale Sharks, and Other Astonishments by Aimee Nezhukumatathil The Science of Kissing: What Our Lips Are Telling Us by Sheril Kirshenbaum Bonk: The Curious Coupling of Science and Sex by Mary Roach I Contain Multitudes: The Microbes Within Us and a Grander View of Life by Ed Yong Clean: The New Science of Skin by James Hamblin What Happens When You Quit Showering? Don't Just Sit There: Transitioning to a Standing and Dynamic Workstation for Whole-Body Health by Katy Bowman Foundation: Redefine Your Core, Conquer Back Pain, and Move with Confidence by Eric Goodman The Cure for Everything: Untangling Twisted Messages about Health, Fitness, and Happiness by Timothy Caulfield Other Media We Mentioned After Man: A Zoology of the Future by Dougal Dixon Man After Man: An Anthropology of the Future by Dougal Dixon The New Dinosaurs: An Alternative Evolution by Dougal Dixon 30-Second Biology: The 50 Most Thought-Provoking Theories Of Life, Each Explained In Half A Minute Know It All Biology: The 50 Most Elemental Concepts in Biology, Each Explained in Under a Minute Grunt: The Curious Science of Humans at War by Mary Roach Stiff: The Curious Lives of Human Cadavers by Mary Roach Packing for Mars: The Curious Science of Life in the Void by Mary Roach Gulp: Adventures on the Alimentary Canal by Mary Roach If Our Bodies Could Talk: A Guide to Operating and Maintaining a Human Body by James Hamblin Links, Articles, and Things Possum Every Hour Cégep (Wikipedia) Why Is Poop Brown? RJ’s Instagram post Plague doctor (Wikipedia) Naukograd (science city) (Wikipedia) Lamarckism (Wikipedia) Lysenkoism (Wikipedia) Genetics and The Modern Synthesis: Crash Course History of Science #35 Cybernetics (Wikipedia) Biology Non-Fiction Books by BIPOC (Black, Indigenous, & People of Colour) Authors Every month Book Club for Masochists: A Readers’ Advisory Podcasts chooses a genre at random and we read and discuss books from that genre. We also put together book lists for each episode/genre that feature works by BIPOC (Black, Indigenous, & People of Colour) authors. All of the lists can be found here. Science in Black and White: How Biology and Environment Shape Our Racial Divide by Alondra Oubré The Spectrum of Sex: The Science of Male, Female and Intersex by Hida Viloria and Maria Nieto Naming Nature: The Clash Between Instinct and Science by Carol Kaesuk Yoon Braiding Sweetgrass: Indigenous Wisdom, Scientific Knowledge, and the Teachings of Plants by Robin Wall Kimmerer Gathering Moss: A Natural and Cultural History of Mosses by Robin Wall Kimmerer Monarchs and Milkweed: A Migrating Butterfly, a Poisonous Plant, and Their Remarkable Story of Coevolution by Anurag Agrawal The Gene: An Intimate History by Siddhartha Mukherjee The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee I Contain Multitudes: The Microbes Within Us and a Grander View of Life by Ed Yong World of Wonders: In Praise of Fireflies, Whale Sharks, and Other Astonishments by Aimee Nezhukumatathil Give us feedback! Fill out the form to ask for a recommendation or suggest a genre or title for us to read! Check out our Tumblr, follow us on Twitter or Instagram, join our Facebook Group, or send us an email! Join us again on Tuesday, 16th we’ll be talking about Bad Book Reading Habits! Join us again on Tuesday, April 6th we’ll be talking about the genre of Psychological Horror! (With a special guest co-host!)
In this episode of the podcast, Sam Harris speaks with Siddhartha Mukherjee about our ongoing failure to adequately respond to the Covid-19 pandemic. They discuss the significance of asymptomatic spread, the lack of Chinese cooperation, the failures of testing, travel restrictions, the missteps of the FDA and the CDC, controversy around masks, the lack of coordination among the states, conspiracy thinking about mortality statistics, the political contamination of public health information, electronic medical records, preparing for the next pandemic, the immunology of Covid-19, the long term consequences of the disease, concerns about a vaccine, the coming prospect of school openings, and other topics. Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbyterian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His laboratory focuses on discovering new cancer drugs using innovative biological methods. He has published articles and commentary in such journals as Nature, New England Journal of Medicine, Neuron and the Journal of Clinical Investigation and in publications such as the New York Times, The New Yorker, and the New Republic. His work was nominated for Best American Science Writing, 2000. He won the Pulitzer Prize for his book The Emperor of All Maladies: A Biography of Cancer. His most recent book is The Gene: An Intimate History. Twitter: @DrSidMukherjee
Do you have a Day One or Day Two mentality and why does it matter? Alex Kantrowitz sits down with Kevin to talk about mindset and culture. Alex is a senior technology reporter at BuzzFeed News and author of Always Day One. Alex interviewed more than 130 tech insiders from hourly workers to executives to share how the “Tech Titans Plan to Stay on Top.” However, the lessons learned don't just apply to Silicon Valley. To become stronger and more successful leaders must continue to look at their business. They recognize change is constant and a Day One mindset will get you to your future state. This episode is brought to you by... From Manager to Remarkable Leader, Kevin's Flagship workshop based on his proven leadership model. Additional Leadership Resources Book Recommendations: Always Day One: How the Tech Titans Plan to Stay on Top Forever by Alex Kantrowitz The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee Connect with Alex Kantrowitz: Website | Twitter Related Podcast Episodes: Connecting Your Company Culture with Your Brand with Denise Lee Yohn. The Power of Corporate Culture with Chris Dyer. How to Think Like Amazon with John Rossman. Turning Culture into Competitive Advantage with Jeff Grimshaw. The Innovation Stack with Jim McKelvey.
Dr. Siddhartha Mukherjee chats about the new PBS documentary series "The Gene" based on his best selling book. The new docuseries is directed and produced by Ken Burns.Dr. Mukherjee is the author of The Emperor of All Maladies: A Biography of Cancer, winner of the 2011 Pulitzer Prize in general nonfiction, and The Laws of Medicine.#talkingpictures #celebrity #interview #flashbacktv #TonyToscano #TheGene #PBS #SiddharthaMukherjee #KenBurns
Before 1947, leukemia was understood to be an untreatable disease, but Dr. Sidney Farber refused to accept this conclusion, and used antifolates, to hopefully restore normal blood.Sidney Farber 1903 - 1973ttps://www.healio.com/hematology-oncology/news/print/hemonc-today/%7B5d9e673c-c88e-43a1-9122-55037e2eb7c7%7D/sidney-farber-1903-1973The Emperor of All Maladies: A Biography of Cancer. Siddartha Mukherjee, M.D. 2010.Buffalo NY flu 1918 - flu encyclopediahttps://www.influenzaarchive.org/cities/city-buffalo.html#Sidney Farber, Chemo Crusader - Saul Wisna - May 27, 2015 - WNYC Archive Collectionshttps://www.wnyc.org/story/sidney-farber-chemo-crusader/1918 Spanish Flu Pandemic Historyhttps://www.cdc.gov/flu/pandemic-resources/1918-pandemic-h1n1.htmlBlood specificshttps://www.oneblood.org/about-donating/blood-donor-basics/what-is-blood/University of Rochester Medical SchoolMonocyte to Macrophage - Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases, Yang, Zhang, et. al. National Institute of Health.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892095/Discovery of Leukemia - NY Timeshttps://www.nytimes.com/2012/06/05/health/history-of-battle-against-leukemia.htmlLeukemia Development from Bone Marrowhttps://my.clevelandclinic.org/health/diseases/4365-leukemiaVitamin B12 Information - National Institute of Healthhttps://ods.od.nih.gov/factsheets/VitaminB12-Consumer/Folic acid Information - ScienceDirecthttps://www.sciencedirect.com/topics/chemistry/folic-acidB12 and Folate Deficiency - National Health Service - UKhttps://www.nhs.uk/conditions/vitamin-b12-or-folate-deficiency-anaemia/Folate Deficiency vs Vitamin B12 Deficiency - Medicosis Perfectionalishttps://www.youtube.com/watch?v=XcKsctwgDcgAminopterin drug information - US Library of Medicine https://pubchem.ncbi.nlm.nih.gov/compound/AminopterinTruth or Consequences Broadcast - Ralph Edwards & Einar Gustafson - Dana-Farber Cancer Institute.http://www.jimmyfund.org/about-us/about-the-jimmy-fund/einar-gustafson-jimmy-was-inspiration-for-the-jimmy-fund/Dr. Sidney Farber Interview. Sidney Farber Chemo Crusader. Saul Wisna. May 27th, 2015. WNYC Archive Collections. https://www.wnyc.org/story/sidney-farber-chemo-crusader/
Dr. Siddhartha Mukherjee is the author of the best-selling book, “The Emperor of All Maladies: A Biography of Cancer." The book won a Pulitzer Prize and became the basis for a Ken Burns documentary series on the subject of cancer for PBS. In this fascinating conversation with Alan Alda, Dr. Mukherjee talks about the extraordinary power scientists like him have now to edit our genes using the tool known as CRISPR. Dr. Mukherjee uses CRISPR in his own laboratory at Columbia University to pioneer innovative ways to treat cancer. Dr. Mukherjee is a masterful storyteller and he possesses an obvious command of the science behind his books. He has a special ability to make science both personal and intimate, as you'll experience in this episode. Support the show.
In 2009, physician, researcher, and science writer, Dr. Siddhartha Mukherjee, published his Pulitzer Prize-winning book, The Emperor of All Maladies: A Biography of Cancer. In it, he describes the story of cancer as a human story marked by ingenuity, resilience, and perseverance, but also hubris, paternalism, and misperception. On November 13, 2019, a panel of physicians and researchers from the VCU Massey Cancer Center discussed the impact of Mukherjee’s book and the groundbreaking advances in cancer research, treatment, and prevention that has emerged during the past decade. A reception will follow the lecture. INTRODUCTORY REMARKS: Ross Mackenzie — Retired Syndicated Columnist and Editor of the Editorial Pages of The Richmond News Leader and the Richmond Times-Dispatch MODERATOR: Peter F. Buckley, M.D. — Dean, VCU School of Medicine PANEL: Walter Lawrence, M.D. — Founding Director, VCU Massey Cancer Center Steven Grant, M.D. — Shirley Carter and Sture Gordon Olsson Chair in Cancer Research; Professor and Eminent Scholar, Internal Medicine, School of Medicine; Associate Director for Translational Research, VCU Massey Cancer Center; Program Co-Leader, Developmental Therapeutics John M McCarty, M.D. — Professor of Medicine, G. Watson James Endowed Professor of Hematology; Interim Chief, Division of Pediatric Hematology/Oncology; Medical Director, Cellular Immunotherapies and Transplant Program; Medical Director, Cellular Therapeutics Laboratory; VCU Massey Cancer Center This was the third program in our Health in History Series, a partnership between the MCV Foundation and the Virginia Museum of History & Culture and sponsored by the Virginia Sargeant Reynolds Foundation.
Learn English with Siddhartha Mukherjee. Siddhartha has a word of advice for this year’s graduates: Listen. Mukherjee is best known for his 2011 Pulitzer Prize-winning book, The Emperor of All Maladies: A Biography of Cancer. It was turned into a three-part documentary by Ken Burns and included among Time magazine’s 100 best nonfiction books of the past century. He is the author of five books, including Start With Why. In this Speech, he also quotes: “Go get out of your heads and go out into the world and listen to it. And most importantly: make us listen to you.” For more, visit: https://www.englishspeecheschannel.com
Best selling author, researcher, scientist, and world-renowned physician Siddhartha Mukherjee joins Chadi to discuss his career path, what led him to write the inspiring book "The Emperor of All Maladies: A Biography of Cancer," and how his writing impacted his practice and vice versa.
In this episode, Siddhartha Mukherjee, oncologist, researcher, and author of the Pulitzer Prize-winning book “The Emperor of All Maladies: A Biography of Cancer,” discusses his writing process, his thoughts about medicine, cancer, immunotherapy, and his recent collaboration on a study combining a ketogenic diet with a drug in mice that provided remarkable and encouraging results. We discuss: Sid’s background [5:00]; How Sid and Peter met [6:00]; Sid’s Pulitzer Prize-winning book: The Emperor of All Maladies [8:00]; Sid’s writing process: the tenets of writing [12:30]; Our struggle to find preventable, human, chemical carcinogens of substantial impact [23:30]; The three laws of medicine — Law #1: A strong intuition is much more powerful than a weak test [26:30]; Law #2 of medicine: “Normals” teach us rules; “outliers” teach us laws [32:00]; Law #3 of medicine: For every perfect medical experiment, there is a perfect human bias [35:00]; The excitement around immunotherapy [38:15]; The story of Gleevec [46:00]; How does the body's metabolic state affect cancer? [49:30]; Can a nutritional state be exploited and/or a drug sensitivity be exploited through a nutritional intervention? [52:00]; How does Sid balance his family, writing, research, laboratory, and patients? [1:00:30]; and More. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.
Berkeley biochemist Jennifer Doudna joins oncologist Siddartha Mukherjee to discuss unprecedented advancements in gene editing and the effect new technologies will have on the future of humanity.Dr. Doudna’s research has led to what is being called the biggest scientific discovery of our era: the development of the genetic editing tool, CRISPR-Cas9. This revolutionary technology has quickly transformed the landscape of genome engineering, creating limitless possibilities for impact within biomedicine, agriculture, climate and energy, and more, including treating — and possibly curing — genetic diseases.Dr. Mukherjee is a celebrated physician and researcher. His book, The Emperor of All Maladies: A Biography of Cancer, won the Pulitzer Prize for nonfiction in 2011, was named one of the 100 most influential books written in English since 1923 by TIME magazine, and was listed as one of the 100 notable books of 2010 by the New York Times magazine.This conversation, which took place on Jan. 18, 2018, was sponsored by the Innovative Genomics Institute.Listen and read the transcript on Berkeley News. See acast.com/privacy for privacy and opt-out information.
This week, it's the latest edition of "Things Haven't Always Been Like This". Farah Peterson teaches us about the judges of the early 1800s and their now-strange-seeming institutional world in which judging and legislating were less distinct and more collaborative. This show’s links: Farah Peterson’s faculty profile (https://www.law.virginia.edu/faculty/profile/fp9r/2708426) Farah Peterson, Interpretation as Statecraft: Chancellor Kent and the Collaborative Era of American Statutory Interpretation (https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3201036) Dark Sky (https://www.hydratext.com/blog/2012/6/5/dark-sky.html) (blog post) Siddhartha Mukherjee, The Emperor of All Maladies: A Biography of Cancer (https://www.amazon.com/Emperor-All-Maladies-Biography-Cancer/dp/1439170916) Oral Argument 168: Galaxy-Sized Diamond (http://oralargument.org/168) (with Maggie McKinley on petitioning in Congress) Richard Verdon, A Large Meteor (https://twitter.com/kjhealy/status/1032589101877395462) Guido Calabresi, A Common Law for the Age of Statutes (https://books.google.com/books/about/A_Common_Law_for_the_Age_of_Statutes.html?id=KSy5QpdRMNsC) Special Guest: Farah Peterson.
Dr. Cliff Hudis is the CEO of the American Society of Clinical Oncology (ASCO). A medical oncologist by profession, he spent three decades at the Memorial Sloan Kettering Cancer Center, one of the most iconic institutions in the world, and served as Chief of the Breast Medicine Service from 1998 to 2016. In June 2016, he took on the role of CEO at ASCO, where he gets to lead the conversation globally about where the profession is going. In this episode of The Culture Gap, Cliff talks about cancer, the gaps in knowledge that have been closed in cancer discovery and research, and what he has learned from his experiences. He also gives us insight into what it takes to lead a team of brilliant professionals to come together for a larger purpose, and the lessons he has gained as a leader driving strategy and culture change. Welcome to Culture Gap. Key Takeaways: [:45] Daniel introduces his guest for this episode — Dr. Cliff Hudis. [1:59] Who is Cliff? [2:47] Who were some of the big influencers in Cliff's life that helped him become who he is today? He shares some of his background. [9:51] As a young oncologist at Memorial Sloan Kettering Cancer Center, what was going through Cliff's mind? Could he have imagined the changes that occurred over the subsequent decades? [13:13] What are some of the gaps in knowledge that have been closed in cancer discovery, specifically breast cancer? Which of these gaps that have been closed have surprised Cliff the most? [20:30] What was it like for Cliff to be a young leader given an incredible authority and responsibility? How did he balance the individuals on his team and respect their autonomy, while still coming together as a group to discover something larger? [26:39] Cliff shares some of his experiences with his patients. [28:08] Why did Cliff want the job as CEO of ASCO? [34:59] Why did Cliff want to set a strategy in the earliest months of his tenure at ASCO, and what are the changes that have happened to the strategy since its inception? [40:41] If Cliff could have a conversation with cancer, what would he ask it? [43:49] What is Cliff's advice to other CEOs? [49:17] Cliff's wife, Jane, is a successful leader in the retail space. What is the best leadership advice Jane has given Cliff as he has taken on his role at ASCO? Brought to You By: The Culture Gap Podcast THRUUE Podfly Productions Learn more about: Dr. Cliff Hudis The American Society of Clinical Oncology The Memorial Sloan Kettering Cancer Center The Emperor of All Maladies: A Biography of Cancer, by Siddhartha Mukherjee The Gene: An Intimate History, by Siddhartha Mukherjee
In this episode we're featuring an excerpt from a recent lecture given by Pulitzer prize-winner Dr. Siddhartha Mukherjee. Dr. Mukherjee is best known for his 2010 book "The Emperor of All Maladies: A Biography of Cancer" and his 2016 book called "The Gene: An Intimate History ". On October 10, 2017 Dr. Mukherjee visited New York University to give the Inaugural William C. Stubing Memorial Lecture called “Are We Ready to Edit Our Genomes?” where he presented a snapshot of the past, present and possible future of gene editing, and raised many scientific, humanistic and ethical questions about this rapidly evolving field. Also joining us on this podcast is S. Matthew Liao, the Director of the Center for Bioethics here at NYU GPH and also the Arthur Zitrin Professor of Bioethics. Stay tuned after listening to Dr. Mukherjee's lecture, as Professor Liao will be joining us in the second part of the episode with some thoughts and reflections about this complex and exciting field of work. To learn more about the NYU College of Global Public Health, and how our innovative programs are training the next generation of public health leaders, visit publichealth.nyu.edu.
Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbyterian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His laboratory focuses on discovering new cancer drugs using innovative biological methods. He has published articles and commentary in such journals as Nature, New England Journal of Medicine, Neuron and the Journal of Clinical Investigation and in publications such as the New York Times, The New Yorker, and the New Republic. His work was nominated for Best American Science Writing, 2000. He won the Pulitzer Prize for his book The Emperor of All Maladies: A Biography of Cancer. His most recent book is The Gene: An Intimate History. Twitter: @DrSidMukherjee
In this episode of the Making Sense podcast, Sam Harris speaks with Siddhartha Mukherjee about his Pulitzer Prize winning book, The Emperor of All Maladies: A Biography of Cancer. You can support the Making Sense podcast and receive subscriber-only content at samharris.org/subscribe.
Sam Harris speaks with Siddhartha Mukherjee about the human desire to understand and manipulate heredity, the genius of Gregor Mendel, the ethics of altering our genes, the future of genetic medicine, patent issues in genetic research, and other topics. Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbyterian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His laboratory focuses on discovering new cancer drugs using innovative biological methods. He has published articles and commentary in such journals as Nature, New England Journal of Medicine, Neuron and the Journal of Clinical Investigation and in publications such as The New York Times, The New Yorker, and The New Republic. His work was nominated for Best American Science Writing, 2000. He won the Pulitzer Prize for his book The Emperor of All Maladies: A Biography of Cancer. His most recent book is The Gene: An Intimate History. Episodes that have been re-released as part of the Best of Making Sense series may have been edited for relevance since their original airing.
Dr. Siddhartha Mukherjee, is assistant professor of medicine at Columbia University, physician at Columbia University Medical Center and author of the Pulitzer Prize winning The Emperor of All Maladies: A Biography of Cancer and the recently published The Gene: An Intimate History. I heard Sid speak at the 10th Annual Future of Genomic Medicine Conference and in this short interview he admits that he is surprised that his books have become so popular with general audiences but that scientists need to talk up to people and assume they can understand more about the implications of genetic breakthroughs. @DrSidMukherjee #FOGM17 @ScrippsSTSI
Dan Wagner is the Founder and CEO of Civis Analytics, a startup that helps companies, non-profits, and campaigns leverage their data to develop smarter strategy, make better decisions, and build stronger, data-driven organizations. Before founding Civis Analytics, Dan Wagner was the Chief Analytics Officer on President Obama's 2012 campaign, overseeing a 54-person team of analysts, engineers and organizers that provided analytics and technologies for voter contact, digital, paid media, fundraising and communication. After a discussion with Eric Schmidt, Executive Chairman of Alphabet Inc., on election night, Dan decided to keep his team together and start a company. In This Episode You Will Learn: How Civis Analytics started with great people and no set idea How President Obama built an empowered meritocracy in his 2012 reelection campaign The differences between building a company and a campaign How Civis Analytics got their first customers What you need to do excellent data science Why the government is getting involved in fighting cancer The timeline for making progress on the cancer moonshot Why they decided to build an innovative data science company in Chicago Why Dan would like to see more risky financing in Chicago The three things you need to ask yourself before starting a company Selected Links From The Episode: David Plouffe, 2008 Campaign Manager to President Obama David Axelrod, Senior Advisor to President Obama Civis Analytics's Cancer Moonshot Report NCI Genomic Data Commons A Few of Dan's Favorite Books: The Emperor of All Maladies: A Biography of Cancer by Siddartha Mukheriee Meditations by Marcus Aurelius Chronicle of a Death Foretold by Gabriel García Márquez "The Future of Data Analysis" (1962) by John Tukey
Cancer is the second leading cause of death among adults in the US and cancer care costs $125 billion a year. In this episode we hear from medical experts who have researched, written, and made progress in the fight against cancer. Ronald DePinho, president of the University of Texas MD Anderson Cancer Center, says it’s an exciting time because research has shed light on the instigators of the disease. With the knowledge we have now, he says, up to half of all cancers can be prevented. He’s featured in the podcast along with Eric Lander, president and director of the Broad Institute of MIT and Harvard, and Siddhartha Mukherjee, author of the Pulitzer Prize-winning book The Emperor of All Maladies: A Biography of Cancer.
Cancer is like a computer program gone wrong, the kernel panic of the human body. Unfortunately, we have no reboot button, and so cancer is the most serious of diseases. This year, almost six hundred thousand Americans will die from cancer. Despite the fact that cancer receives more NIH funding than any other illness, the death rates remain the same as in the 1950s. Tripping Over the Truth: The Return of the Metabolic Theory of Cancer tells the story of molecular biologist and science writer Travis Christofferson’s journey to discover why cancer has remained so elusive. The central theme of the book is that we’ve fundamentally mischaracterized the origin of cancer. Most scientists hold to the belief that cancer is a genetic disease, Travis explores the idea that cancer is, in fact, a disease of damaged metabolism. The metabolic theory of cancer stems from Nobel laureate Otto Warburg’s observation in 1924 that cancer cells lack the ability to produce energy using anything other than an ancient and inefficient process of fermentation. Warburg’s idea failed to gain critical mass, and by the 1960s had largely faded into oblivion. In 2012, Thomas Siegfried, Ph.D., released his book Cancer as a Metabolic Disease where he expanded on Warburg’s original hypothesis. In his book, Siegfried described how all cancer cells have damaged mitochondria, the organelle responsible for creating energy with oxygen. Inspired by The Emperor of All Maladies by Siddhartha Mukherjee, Travis has done a excellent job of telling the rich story behind the metabolic theory of cancer. In this interview, Travis and I discuss some of the potential benefits and mechanisms of a ketogenic diet, hyperbaric oxygen, gluconeogenesis inhibitors and ketone supplements as possible cancer therapy. I would like to thank Dr. Tommy Wood for some of the questions asked in this interview, especially those about glioblastoma and women with the BRCA1 mutation and breast cancer. Here’s the outline of this interview with Travis Christofferson: 0:00:15 Book: Tripping Over the Truth: The Return of the Metabolic Theory of Cancer Illuminates a New and Hopeful Path to a Cure 0:00:34 How Travis became in terested in biology. 0:00:54 Travis has a fundamental curiosity. 0:01:10 The best doctors are the ones that do experiments on themselves. 0:01:22 Book: Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer by Tom Siegfried. 0:01:38 Book: The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee. 0:02:16 Travis wanted to tell the rich story behind the science in Tom's book. 0:03:01 Podcast: Dominic D'Agostino on the Tim Ferriss show. 0:03:30 The Emperor is gene centric. 0:03:46 The difference between the genetic and metabolic theories of cancer. 0:04:08 Radiation, cell repair. 0:04:09 In the genetic theory, cancer arises through lesions on DNA. 0:04:43 The genetic theory is still the dominant theory. 0:04:55 In the metabolic theory, cancer is proliferated by damage to the mitochondria. 0:05:07 Cancer resorts to less efficient fermentation. 0:05:25 This less efficient metabolism sends a message to the DNA. 0:05:42 This new theory makes cancer look like a disease of order. 0:06:02 Everything that causes cancer damages mitochondria. 0:06:39 Paul Davies, cosmologist. 0:07:07 Worked with Stephen Hawking. 0:07:33 Video: Anna Barker at TEDMED 2010. 0:07:53 Cancer is incredibly complex compared to other diseases. 0:08:19 In 2008 atavistic model 0:08:48 Three million studies on cancer on PubMed. 0:09:20 In the beginning, there was single celled organisms. 0:09:26 With multicellular life, the rules changed. 0:09:43 The foetal genes are reexpressed in cancer. 0:10:03 This new understanding gives hope. 0:10:17 What can we do with this new knowledge. 0:10:28 Look after our mitochondria. 0:10:38 A ketogenic diet is a great way to achieve this. 0:10:48 Also intermittent fasting. 0:10:57 Metformin as an oncology drug. 0:11:20 Exploiting the express of early genes. 0:11:44 The Warburg Effect. 0:11:53 Hyperbaric oxygen. 0:12:01 Cancer cells decouple of the adaptive immune system. 0:12:07 Cancer patients with high fever then spontaneous remission. 0:12:25 Cancer cannot withstand infection. 0:12:56 How does the ketogenic diet work against cancer? 0:13:04 Lowering blood glucose. 0:13:11 Glucose is the preferred fuel of cancer. 0:13:25 Some cancers can utilise ketones. 0:13:45 But there's promise in all cancers. 0:14:05 There's some kind of signalling mechanism. 0:14:27 Less side-effects with chemo after fasting. 0:15:05 Dr. Tommy Wood pointed me at some studies showing that certain breast cancers can use ketones as fuel. One study of women with the BRCA1 mutation showed that those with upregulated ketone metabolism did worse, which suggests that a cancer can develop metabolic flexibility too, and would be able to avoid death on a ketogenic diet. 0:15:27 Everybody is different and your results therefore will vary. 0:15:51 The brain can obtain up to 80% of its energy requirenents from ketones. 0:16:09 Some neurons are too small to include a mitochondria. 0:16:21 There is a trial going on in Arizona with glioblastoma. 0:16:25 Dr. Adrienne C. Scheck. 0:16:29 Results by April. 0:16:41 Kid in Norway, prognosis is 8 months, that was 3 years ago. 0:17:12 Tumor has shrunk and remained stable now for 3 years. 0:17:31 Metabolic therapies are good at managing cancer, but may not be the cure. 0:17:55 The studies are all done from the same line of glioblastoma. 0:18:17 Glioblastoma is where the research started, but the principle is sound 0:18:41 Will glioblastoma be the first cancer that we see a cure for? 0:18:48 Glioblastoma is usually about a year from the time of diagnosis to death. 0:19:17 How do cancers show up in a PET scanner? 0:19:24 PET scanners detect radiolabeled glucose. 0:19:43 The tumour outcompetes normal cells for glucose and show they show up in the scanner. 0:20:25 If the tumours have been lighting up in scanners for a long time, why has it taken so long for anyone to think of this? 0:20:41 Dr. Scheck’s study is using a standard ketogenic diet. 0:20:43 In some people that doesn't drive down glucose very far. 0:21:06 You can drive blood glucose very low. 0:21:21 In extended fasts, blood glucose would go down in the 60s (mg/dL). 0:21:24 Now we have exogenous ketone supplementation. 0:21:27 And gluconeogenesis inhibitors. 0:22:50 What were gluconeogenesis inhibitors originally designed for? 0:23:05 We're only just starting to appreciate Metformin. 0:23:06 25-30% reduction in the chances of getting cancer on Metformin. 0:23:07 Nobody really knows how is works. 0:23:31 Phenylbutyrate. 0:23:55 Metformin also inhibits complex 1 of the ETC. 0:24:07 ROS are bad, but also signalling molecules. 0:24:23 Another line of research has shown that Metformin works through altering the gut microbiome. 0:24:44 Podcast: Exercise is an antioxidant. 0:25:02 Podcast: Tommy and me on the Robb Wolf podcast. 0:25:11 Podcast: Insulin resistance. 0:25:15 Podcast: Iron overload. 0:25:46 In biology, you focus on one thing. One protein, one pathway. 0:25:55 Dr. Coe? in Travis's book. 0:25:56 ATPase. 0:26:15 You need someone to do the detailed work, but then you need someone to step back. 0:26:30 Physics already has a mechanism in place to do that. 0:27:05 In physics, you can come up with an idea and there's more than enough data to test it out. 0:27:31 Worse, in nutrition the data conflicts each other. 0:27:33 The NCI said that 80% of the basic research in cancer biology were not reproducible. 0:27:56 Sorting through the studies is an art form. 0:28:08 Warren Buffett. 0:28:22 What do you think of the meta-analysis? 0:28:53 This is the Gold Standard of science! 0:29:11 Book: Good Calories, Bad Calories: Fats, Carbs, and the Controversial Science of Diet and Health by Gary Taubes 0:30:36 Ketone supplements are not currently be used in cancer therapy. 0:31:09 Dominic D'Agostino specialises in ketone supplementation. 0:31:34 Ketones are far more than a macronutrient. 0:31:49 Ketones are anti-inflammatory. 0:32:08 Seasonal ketosis. 0:32:22 Dr. Veech at the NIH: "it's not normal to have a McDonald’s on every street corner". 0:32:30 It's normal to starve periodically. 0:32:53 Alzheimer's is now being called type 3 diabetes. 0:33:41 Is it a good idea to be constantly in ketosis? 0:33:58 Dr. Peter Attia. 0:34:32 Two studies, one at the National Institute of Aging, one at the University of Wisconson 0:34:37 Caloric restriction in monkeys. 0:34:49 Caloric restriction doesn't help as much as we thought. 0:35:02 The monkeys fed a high-sugar diet did worse. 0:35:27 When is all this going to be more widely know, or even the standard of care? 0:35:40 Things move slowly, it's easy to get depressed. 0:35:57 The trial in Arizona could be groundbreaking. 0:36:34 3-Bromopyruvate (3BP) could be the final piece for the metabolic therapy. 0:37:05 Heroin as the treatment for cocaine addiction. 0:37:47 Radical mastectomy. 0:38:25 This went on for 80 years. 0:38:37 In the end, we discovered that a local lumpectomy was as effective. 0:38:58 The trials are so slow and expensive. 0:39:16 You have to eat something, why not this?. 0:39:42 Travis talked at Paleo f(x). 0:39:57 Anecdotally, word is getting out there. 0:40:24 The ketogenic diet to treat recurrence. 0:40:37 The ketogenic diet is empowering. 0:41:11 Travis wrote an article about recurrence on his website. 0:41:20 It's not about always about a single cell that got left behind. 0:41:36 20% of cases are new, i.e. the environment for cancer is still there. 0:42:09 The same is true of bacteria, if you create the environment, it will grow. 0:42:25 Nobody wants to take high-fat diets seriously for weight loss until we're talking about cancer. 0:42:48 Cachexia is the the worst case scenario. 0:43:40 Valter Longo, PhD. 0:44:21 The state of ketosis doesn't say anything about weight loss, and may even be protective against muscle wasting. 0:44:42 Travis and Dominic's articles on Robb Wolf's website. 0:45:41 The Charlie Foundation. 0:46:04 Travis's new blog with podcast, Metabolic Optimization. 0:46:43 Dominic holds the Guinness World record for the most weight squatted in 24 hours (he broke the record in six). 0:47:15 Travis is a fulltime author.
Does life exist on other planets? If we discover an alien civilization, does that mean God won’t love us or hang out anymore? Is Allen’s alien superpower the lamest thing ever or the greatest? Our co-hosts answer these questions and more in this week’s episode on God and aliens. Conversation on Faith and Aliens (00:25) Alien Superpower Segment (47:46) RELEVANT LINKS NASA Confirms Evidence That Liquid Water Flows on Today’s Mars (article) Ancient Cosmology (image) Lion King Astronomy Clip (youtube video) How many stars can you see on a clear, moonless night? (article) The Milky Way's 100 Billion Planets (NASA article) Exoplanet History - From Intuition to Discovery (article) How Many Galaxies Are there? (article) The Fermi Paradox — Where Are All The Aliens? (1/2) (youtube video) Kardashev Scale (wikipedia article) The Deep Future: Crash Course Big History #10 (youtube video about potential human colonization of the galaxy) A New Physics Theory of Life (article on “life arises when you shine light at matter for long enough”) Life Might Spread Across Universe Like an 'Epidemic' in New Math Theory (“panspermia article) C.S. Lewis’ Space Trilogy (book series) What C.S. Lewis thought about space exploration and aliens (article) Xenocide: Volume Three of the Ender Quintet (book) Creationist Ken Ham Says Aliens Will Go To Hell So Let's Stop Looking For Them (article) Pope Francis says he would baptise aliens: 'Who are we to close doors?' (article) Poisonwood Bible (book) Water On Mars! (Political cartoon of Nestle drilling for water) Process Theology (wikipedia article) Open Theism (wikipedia article) Fact or Fiction?: NASA Spent Millions to Develop a Pen that Would Write in Space, whereas the Soviet Cosmonauts Used a Pencil (article) The War on Science (youtube video - “the bank bailout cost more than NASA’s entire 50 year running budget”) The Emperor of All Maladies: A Biography of Cancer (book) The Martian (book) How a book about fish nearly sank Isaac Newton's Principia (article) Tardigrades (wikipedia article) And God Blessed The World With The Babel Incident (article - an irenicon) Why Christians should get on board with space exploration (article) Health Benefits Of Bananas And Their Peels: 10 Unusual Ways To Use The Entire Fruit (article) Doctor Who (TV show) Firefly (TV Show) The James Bond gadget that turns you into a FISH: Mask lets you breathe underwater without oxygen tanks (article) Use Your imagination - Hook (youtube video) CORRECTIONS For this episode (032): “The History of Fishes” was published in the 17th century (1686), Allen misspoke -- apologies. THANK YOU Thank you to Mike Golin for our intro and outro music. Check out his band Soulwise. WE WANT TO HEAR FROM YOU Thank you for supporting the podcast! Your ratings, reviews and feedback are not only encouraging to us personally, but they help others find the show. If you appreciate the content we provide please rate, review and subscribe to the podcast on iTunes and Stitcher. Join our conversations on faith and culture by interacting with us through the following links: Read Us on our blog An Irenicon Email Us at podcast@irenicast.com Follow Us on Twitter and Google+ Like Us on Facebook Listen to Us on iTunes, Stitcher, SoundCloud and TuneIn Speak to Us on our Feedback Page Love Us
This week Dave and Gunnar talk about home storage, open source 5th columnists at MSFT, the Amazon unicorn factory, Gunnar’s new job, new workflow, and Georgios Papanikolaou, a monthly visitor of guinea pigs. Subscribe via RSS or iTunes. Image courtesty of @feitclub Redshift in EPEL dynamically adjusts screen brightness and color based upon location and time of day like f.lux OpenSpritz and FBReader OpenSpritz Plugin for speed reading! Dave’s choice is jetzt on Firefox with a workaround Lauren, now in ebook form and as an Opensource.com 2014 People’s Choice Award nominee Bonus link: Ellie the robot is ready to compete Gunnar is thrilled about a revamped and open sourced dgshow.org his other new new project Soren! Gunnar’s Drobo 2.0? — Google Drive prices slashed! Anyone try Insync? Is Space Monkey the device Gunnar thought he heard mentioned on Back to Work? Anyone try the Synology Dropbox-like storage product? Goodyear Zeppelin arrives near Dave’s house Goodyear’s next generation iconic airship takes flight RHEL 6.6’s plans for inclusion of the SCAP Security Guide Heartbleed: oy. See if your favorite web site is vulnerable ← Runs on OpenShift! Sleep well — Red Hat has you covered Open Wifi: don’t listen to this radio in my window. By extension, is it then illegal to strobe someone else’s server? Gunnar’s been complaining about this since 2003 Microsoft releases source code for its OS and Word (MS-DOS 1.1 and 2.0 and Word for Windows 1.1a specifically) Microsoft Launches .NET Foundation To Foster The .NET Open Source Ecosystem AWS urges developers to scrub GitHub of secret keys ATM operators eye Linux as alternative to Windows XP Dave and Gunnar need this like we need smart watches: Google and Microsoft are out to stop dual-boot Windows/Android devices Nice open source list of 2 factor authentication sites + ways to pester those who don’t have it yet HT Dave Sirrine: ScratchJr — Coding for Young Kids Cisco cozies up to Red Hat and KVM RHEL on Google Compute Engine with Cloud Access! AWS Achieves DoD Provisional Authorization RIP, the server. It’s time to breathe the air of cloud connection ‘Amazon has destroyed the unicorn factory’ … How clouds are making sysadmins extinct AFSPC CIO thinks we’re doing consolidation, not cloud. Agree? Disagree? Talk amongst yourselves. HT Bob Kozdemba: How to request resources for Non-Profit, Open Source, or Educational Institutions A Customer We Like: NASA and their launch control center firing room featuring Red Hat (Enterprise) Linux (6)! slack.com looks really interesting for collaboration Gunnar plays with capture tools like NewsBlur and Blogtrottr but can’t quit rss2email and processing tools like Pinboard which he still needs to figure out D&G Book Club: The Emperor of All Maladies: A Biography of Cancer Ken Burns 6 hour documentary coming in 2015 The pap test for cervical cancer screening is due to Georgios Papanikolaou in 1928 where he studied the menstrual cycles of guinea pigs Related: The Immortal Life of Henrietta Lacks — start with the Radiolab episode and follow up episode Bonus book: Proficient Motorcycling: The Ultimate Guide to Riding Well Cutting Room Floor Pretty great interview with Horowitz of Andreesen Horowitz A persuasive case for government-run/subsidized Internet Semantic Versioning — It’s a thing Amazon Dash: genius Make your own GitHub ribbon with CSS alone Twilight Zone action figures (in black and white!) The Expert JakToGo: Great for smuggling hams into movie theaters too We Give Thanks Dave Sirrine for letting us know about ScratchJr Bob Kozdemba for helping spread the word about free OpenShift for non-profit, open source, and educational institutions
Siddhartha Mukherjee, winner of the 2011 Pulitzer Prize in nonfiction for his book The Emperor of All Maladies: A Biography of Cancer, examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an … Continue reading →
SHOW NOTE คุยเรื่องต้นกำเนิด "มะเร็ง" กับหมอเอ้ว ชัชพล เกียรติขจรธาดา รายละเอียดรูปเซลมะเร็งข้างบน - 1,2,3 หนังสือของพี่เอ้วมี 2 เล่มชื่อ "เรื่องเล่าจากร่างกาย" และ "เหตุผลของธรรมชาติ" หาซื้อได้ตามร้านหนังสือชั้นนำทั่วไป บรรยากาศห้องอัด - เซลมะเร็งในร่างกายค่อยๆ วิวัฒนาการผ่านกระบวนการคัดเลือก เปรียบได้กับวิวัฒนาการของสิ่งมีชีวิตระดับใหญ่ - 1,2,3,4,5,6,7,8 ถ้าอยากอ่านหนังสือเกี่ยวกับประวัติและที่มาของมะเร็ง เล่มนี้น่าสนใจครับ "The Emperor of All Maladies: A Biography of Cancer" - เรื่อง trade off เรื่องวิถีชีวิตปัจจุบันที่เปลี่ยนเร็วจนร่างกายวิวัฒนาการตามไม่ทัน จึงเป็นเหตุให้เกิดโรคต่างๆ - การใช้มุมมองของวิวัฒนาการวิเคราะห์ที่มาของโรคภัยไข้เจ็บต่างๆ เรียกว่าศาสตร์แขนง Darwinian medicine หรือ Evolutionary medicine -1,2,3,4,5 / / / รวมพวกปรสิตทั้งหลายที่พูดถึง - Toxoplasma gondii ทำให้หนูไม่กลัวแมว - พยาธิ Leucochloridium paradoxum ที่ทำให้หอยทากตาปูดเหมือนหนอน ล่อนกมาจิกกิน [youtube http://www.youtube.com/watch?v=fkiL-v4X8w8] - รา cordyceps ที่ทำให้มดกลายเป็นซอมบี้ https://www.youtube.com/watch?v=XuKjBIBBAL8 - พยาธิ hairworm ที่ทำให้ตั๊กแตนโดดน้ำตาย - วิดิโอ http://www.youtube.com/watch?v=D7r1S6-op8E http://www.youtube.com/watch?v=ojKIw4ZY9fE http://www.youtube.com/watch?v=e6iiPCQw7hY / / / ส่วนนี่คือเจ้าตุ๊กตาเต่าเบร้อตัวที่ป๋องแป๋งขำไม่หยุด จริงๆ มันคือของเล่นหมาแหละ แต่ผมชอบมากเลยเอามาตั้งโต๊ะซะ
From its first documented appearances thousands of years ago, through the epic battles in the 20th century to control it, the story of cancer is a story of human ingenuity and resilience. On Thursday's program, we'll talk with the Pulitzer Prize winning author of "The Emperor of All Maladies: A Biography of Cancer. It is the amazing story of the people and tools, drugs and tumors, chemicals and experiments that have led us to modern day treatments and therapies.
Medical author Siddhartha Mukherjee appears at the 2011 National Book Festival. Speaker Biography: "The Emperor of All Maladies: A Biography of Cancer" (Scribner), which won the 2011 Pulitzer Prize for general nonfiction, is Siddhartha Mukherjee's story of this dreaded disease -- from its origins to the global battle to cure, control and conquer it. Mukherjee is a cancer physician and researcher. An assistant professor of medicine at Columbia University and a staff cancer physician at Columbia University Medical Center, he is a Rhodes scholar with degrees from Stanford University, the University of Oxford and Harvard Medical School. He has published articles in Nature, The New England Journal of Medicine, The New York Times and The New Republic. For captions, transcript, and more information visit http://www.loc.gov/today/cyberlc/feature_wdesc.php?rec=5314.
Cancer is always a devastating diagnosis and too many times it is a final verdict for its victims. On Thursday's program, we'll talk with the Pulitzer Prize winning author of "The Emperor of All Maladies: A Biography of Cancer. It is much more than a story of uncontrolled cell growth, it is a history of battles waged over thousands of years and the people and tools, drugs and tumors, chemicals and experiments that have led us to modern day treatments and therapies.
Guest Siddhartha Mukherjee, Assistant Professor of Medicine, Columbia University, speaks with Diane Horn about his book "The Emperor of All Maladies: A Biography of Cancer."
Oncologist and acclaimed author Siddhartha Mukherjee takes us on a journey through the long and complex history of cancer, and discusses what it took to bring his Pulitzer Prize winning book, The Emperor of All Maladies: A Biography of Cancer, to life. Mukherjee spoke at the Academy on April 14, 2011 as part of the Science the City speakers series. The event was co-sponsored by the Farber Center for Radiation Oncology.