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Recorded after a snowy weekend on a Monday night at the Palm Street Studio with Grumpy Griller's chili! Jardiance takes its toll on your taint and ruins holiday tv viewing with Phil's son. A great band name comes from the chaos. The Rock has a very funny SNL commercial about a certain medication. Urban DIC calls in to bring shame to our team's opponent's cities and fans. Is it over for the Lions? Some stoner thoughts and lots of taint talk. Featuring Brian "Bandit", The Grumpy Griller, Brian "The Blade", Hall of Famer Junior!, Phil Nichol, and Adam Filkins. Make good choices!
Federal hükümet, PBS yani İlaç Destek Programı'na kronik böbrek hastalığı için bir ilaç ekleyecek. 65.000'den fazla Avustralyalının, Empagliflozin olarak da bilinen Jardiance 'a daha ucuz erişimden faydalanması bekleniyor.
Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In today's episode I dive deep into a topic that almost nobody talks about even though it affects tens of millions of people every single year. We're breaking down the full peptide stack for kidney health and renal longevity. When I first got into biohacking I didn't think much about kidneys at all. I assumed they just silently did their thing in the background. But over the years, as I started working with more people and publishing more content, I realized how common kidney dysfunction is and how quickly it can go downhill if you don't catch it early. That's when I went down the rabbit hole of what actually causes kidney decline and what we can do to strengthen and protect renal function long before a diagnosis ever shows up.Inside this episode I walk through the most important vulnerabilities the kidneys face as we age. These are things like oxidative stress, mitochondrial breakdown, metabolic strain, hypertension, hyperglycemia, inflammation, structural damage to the filtration barrier, and even vascular deterioration. Most people don't realize the kidneys use up to ten percent of the body's entire oxygen supply which makes them extremely sensitive to damage. I explain exactly how these vulnerabilities accumulate over time and why proactive support is just as important for someone who is “normal” as it is for someone with early-stage CKD.From there I walk you step-by-step through the five-peptide kidney restoration protocol I put together. This stack includes SS-31, Jardiance, glutathione, ARA-290, and MOTS-C. I explain what each one does, why it matters, the exact dose and frequency I recommend, and what role it plays in repairing, protecting, and unloading the kidneys. I talk about mitochondrial protection, reducing hyperfiltration, lowering mechanical stress, restoring antioxidant defenses, repairing microvasculature, activating AMPK, improving metabolic flexibility, and reversing early fibrosis. This isn't theory. I've watched these compounds move the needle for real people in the real world.I also walk you through the synergy of the full stack. When these agents work together, they offload the metabolic burden on the kidneys while strengthening the cellular machinery that has to keep you alive for decades. I compare it to walking around with a sixty-pound weight vest: eventually that load catches up. This protocol systematically removes that load while improving the kidney's structural resilience at the same time.At the end I cover what to monitor on bloodwork, how to cycle the protocol, what can be used long-term, and the signs you want to get in front of before they spiral into full kidney disease. Whether you have diagnosed kidney problems or you simply want to protect your renal function as part of your longevity plan, this episode gives you a blueprint you can use immediately.As always, make sure you are on my email list so you never miss my content even if platforms delete me. Thank you for being here and letting me bring this information to you. I have so much gratitude for everyone supporting the channel. Enjoy the episode and share it with anyone who needs it.
ඕස්ට්රේලියානු ෆෙඩරල් රජය ඖෂධ ප්රතිලාභ යෝජනා ක්රමයට නිදන්ගත වකුගඩු රෝග සඳහා ලබාදෙන ඖෂධයක් එකතු කරන බව නිවේදනය කළා. Jardiance නැතහොත් එම්පැග්ලිෆ්ලොසින් ලෙසද හැඳින්වෙන මෙම ඖෂධය BSP පහසුකම වෙත ඇතුලත් කිරීමෙන් 65,000 කට වැඩි ඕස්ට්රේලියානුවන් පිරිසකට ප්රතිලාභ ලබනු ඇතැයි අපේක්ෂා කෙරේ. අද කාලීන විග්රහයෙන් විමසා බැලෙන්නේ මේ පිළිබඳවයි.
Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I dive deep into what I believe could be the most powerful synergy in the entire world of longevity and metabolic optimization — the combination of SGLT2 inhibitors (like Jardiance and Farxiga) with GLP-1 agonists (like Retatrutide, Tirzepatide, and Semaglutide).These medications were originally created for diabetics, but what we're learning now is that they may be rewriting the entire playbook on healthspan and lifespan extension. I break down the research showing how SGLT2 inhibitors not only lower blood glucose but also improve cardiovascular health, protect the kidneys, reduce inflammation, and even clear senescent cells — all while mimicking the effects of caloric restriction and fasting.Then, I explain how pairing them with a GLP-1 creates a metabolic symphony unlike anything else we've ever seen. Together, they reduce insulin resistance, improve energy metabolism, and activate the same longevity pathways linked to caloric restriction, AMPK activation, and mitochondrial renewal.If you care about living longer, staying leaner, and protecting every organ system in your body, this episode is a must-listen. I share what I've seen personally, what's happening in clinical data, and why I believe the GLP-1 + SGLT2 combo could end up being one of the greatest discoveries in modern medicine for both health and performance.
ကီၢ်စၢဖှိၣ်ပဒိၣ်ကပၢနုာ်ဃုာ်ဝဲဒၣ် ကသံၣ်လၢပှၤအိၣ်ဒီး ကလ့ၢ်တၢ်ဆါယံၤထၢသ့ၣ်တဖၣ်အဂီၢ်ဖဲ Pharmaceutical Benefits Scheme, ကသံၣ်ကသီတၢ်န့ၢ်ဘျုးအတၢ်ရဲၣ်တၢ်ကျဲၤ အပူၤန့ၣ်လီၤ. မ့ၢ်လၢတၢ်အံၤအဃိ ပှၤအီစထြ့လယါဖိအါန့ၢ် ၆၅,ဝဝဝ ဂၤ အိၣ်ဒိးတၢ်မုၢ်လၢ် လၢကဒိးန့ၢ်ဘၣ် တၢ်အဘျုးအဖှိၣ် ခီဖျိလၢကသံၣ်ဒ်သိး Jardiance, လၢအဘၣ်တၢ်သ့ၣ်ညါစ့ၢ်ကီးအီၤဒ်သိး, Empagliflozin န့ၣ် အပှ့ၤကဘၣ်လီၤဒၣ်အဃိန့ၣ်လီၤ.
Savezna vlada će u Program farmaceutskih beneficija dodati lijek za hroničnu bolest bubrega. Očekuje se da će više od 65.000 Australaca imati koristi od jeftinijeg pristupa lijeku Jardiance, poznatom i kao Empagliflozin.
Од сада ће још око 70.000 Аустралијанаца моћи да по сниженој цени набављају лек Емпаглифлозин, који се продаје под именом Џардијанс (Jardiance), саопштила Савезна влада. Ова терапија која може да успори даље оштећење бубрега и да помогне у дужем очувању њихове функције, доступна је кроз Програм фармацеутских бенефиција (ПБС) по цени од 7,70 долара за власнике концесионих картица, односно 31,60 долара за остале који испуњавају услове. Од 1. јануара 2026. следи ново појефтињење.
Ua fa'aopoopo e le mālō tele le vailaau togafitiga mo fatuga'o, le Jardiance i le lisi o vaila'au togafitiga i lalo o le Pharmaceutical Benefits Scheme (PBS).
The federal government will add a medicine for chronic kidney disease into the Pharmaceutical Benefits Scheme. More than 65.000 Australians are expected to benefit from the cheaper access to Jardiance , also known as Empagliflozin. - Hukûmeta federal dê dermanekî nexweşiya gurçikê ya kronîk li Bernameya Feydeyên Dermanan (PBS) zêde bike. Tê payîn ku zêdetirî 65.000 Australî dê dermanê Jardiance, ku wekî Empagliflozin jî tê zanîn, sûdê werbigirin.
Rząd federalny włączy lek na przewlekłą chorobę nerek do programu Pharmaceutical Benefits Scheme (PBS) – systemu refundacji leków w Australii. Ponad 65 tysięcy Australijczyków ma skorzystać z tańszego dostępu do leku Jardiance, znanego także jako empagliflozyna.
El Gobierno australiano ha anunciado que el medicamento Jardiance, utilizado para tratar la enfermedad renal crónica, se incorporará al PBS, reduciendo su costo y beneficiando a más de 65.000 australianos.
澳大利亚联邦政府将把一种用于治疗慢性肾病的药物纳入药品福利计划(PBS)。预计将有超过6.5万名澳大利亚人受益,人们将能够以更便宜的价格购买一款名叫恩格列净(Jardiance)的肾病药物。
Chính phủ liên bang sẽ bổ sung một loại thuốc điều trị bệnh thận mãn tính vào Chương trình Phúc lợi Dược phẩm PBS. Hơn 65.000 người Úc sẽ được hưởng lợi từ việc tiếp cận thuốc Jardiance, còn được gọi là Empagliflozin, với giá rẻ hơn.
Dowladda federaalka ayaa barnaamijka Pharmaceutical Benefits Scheme (PBS) ku dartay daawo lagu daweeyo cudurka kelyaha. In ka badan 65,000 oo reer Australia ah ayaa la filayaa inay ka faa'iidaystaan helitaanka daawadan oo la yiraahdo Jardiance.
The federal government will add a medicine for chronic kidney disease into the Pharmaceutical Benefits Scheme. More than 65.000 Australians are expected to benefit from the cheaper access to Jardiance , also known as Empagliflozin.
Dr. K talks with geriatric diabetes expert Dr. Sei Lee about the different medications available to treat diabetes, including Ozempic and Jardiance, and how to use them safely and effectively in later life.
What can help a woman in her mid-40s with breast calcifications? Would taking supplements and enzymes help?My husband suffered from hospital delirium and seven months later is still strugglingIs milk thistle beneficial to take? I read an article that curcumin is highly toxic to the liver. What say you?
More on lithium orotate for Alzheimer's diseaseMy sister had cow valve surgery and has to take Jardiance. Are there other alternatives?I'm taking BHRT for hot flashes. Are there any other drugs I should consider taking?
Join Drs. Neil Skolnik and Sara Wettergreen as they answer one of the most common questions people living with diabetes have: “What diabetes medication is best for me?” In this episode, they'll explore how choosing the right medication depends on your individual health, lifestyle, and goals. Discover practical tips to better help you work with your care team to make informed decisions and find the best treatment plan for you. Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health, Abington, PA Sara Wettergreen, PharmD, BCACP, BC-ADM, Assistant Professor, Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences; and Ambulatory Care Clinical Pharmacist, UCHealth Lone Tree Primary Care, Aurora, CO Do you have questions or comments you'd like to share with Neil and Sara? Leave a message at (703) 755-7288. Thank you for listening, and don't forget to “follow” Diabetes Day by Day! Diabetes Medications: Biguanides Brand: Glucophage, Fortamet, Glumetza Generic: Metformin, Metformin XR Sulfonylureas (Second Generation) Brand: Glucotrol, Amaryl, Diaβeta, Glynase Generic: Glipizide, Glipizide XL, Glimepiride, Glyburide Thiazolidinediones (TZDs) Brand: Actos, Avandia Generic: Pioglitazone, Rosiglitazone (no longer available) DPP-4 Inhibitors Brand: Januvia, Onglyza, Tradjenta, Nesina Generic: Sitagliptin, Saxagliptin, Linagliptin, Alogliptin SGLT2 Inhibitors Brand: Invokana, Farxiga, Jardiance, Steglatro, Brenzavvy Generic: Canagliflozin, Dapagliflozin, Empagliflozin, Ertugliflozin, Bexagliflozin GLP-1 Receptor Agonists Brand: Victoza, Trulicity, Ozempic, Rybelsus, Mounjaro (dual GIP/GLP-1) Generic: Liraglutide, Dulaglutide, Semaglutide, Tirzepatide Insulins (selected examples) Brand: Humalog, NovoLog, Apidra, Lantus, Basaglar, Levemir, Tresiba, Humulin N, Novolin N, Humulin R, Novolin R Generic: Insulin lispro, Insulin aspart, Insulin glulisine, Insulin glargine, Insulin detemir, Insulin degludec, NPH insulin, Regular insulin
Forget Hollywood. The real celebrities are the people fake-dancing in Big Pharma commercials while a voice rattles off side effects like “anal leakage, sudden death, and mild jazz hands.” The Rizzuto Show crew plays America's new favorite game: Guess That Drug Ad! From Wegovy to Jardiance, we break down which pill pays the bills, who's dancing in the rain, and why TV is basically just one giant pharmaceutical catalog. Follow The Rizzuto Show @rizzshow on all your favorite social media, including YouTube, Facebook, Twitter, Instagram, TikTok, and more. Connect with The Rizzuto Show online at 1057thepoint.com/rizz See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode we discuss: Jay Campbell, Hunter Williams, and Mark Bell's supplement stacks for staying insulin sensitive on the sugar diet Whether using Metformin while on the sugar diet helps improve insulin sensitivity The major differences between the sugar diet and the bioenergetic approach Real-life examples of weight regain and other negative experiences after the sugar diet Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/ Theresa's Instagram: https://www.instagram.com/livingrootswellness/ Timestamps: 0:00 – intro 0:24 – the costs of metformin: mitochondrial toxicity, increased lactate, inefficient ATP production, and slowed metabolism 5:22 – is using Metformin a good idea on the sugar diet? 10:30 – the dangers of increasing FGF21 while on Metformin 13:53 – increasing FGF21 activity is counter to the bioenergetic view of health 20:23 – Hunter Williams' supplement stack for insulin sensitivity: metformin, Jardiance, retatrutide, and dihydroberberine 21:42 – the negative effects of Jardiance 24:59 – whether retatrutide and other GLP-1 agonists are healthy from a bioenergetic perspective 27:30 – whether there are any benefits to using medications like metformin, Jardiance, retatrutide, and dihydroberberine 31:54 – how increasing FGF21 with the sugar diet could lead to heart problems such as arrhythmias and atrial fibrillation (AFIB) 38:58 – does the sugar diet boost metabolic rate the same way the bioenergetic approach does? 46:27 – examples of how the sugar diet downregulates metabolism through stress 50:51 – the cumulative effects of stress: how much stress can we handle? 55:15 – how to recover from the negative effects of the sugar diet 58:24 – is stress beneficial? is it possible to avoid stress altogether? 59:51 – problems with dropping fat too low, especially in lean individuals 1:03:50 – the risks of rapid weight loss and the importance of keeping long-term goals in mind 1:08:02 – why cutting out entire macronutrient groups can backfire and what to do instead 1:11:20 – how extreme diets prime our bodies for weight regain 1:14:54 – real-life examples of weight regain after the sugar diet and why it happens 1:20:18 – is there a smarter way to do the sugar diet? 1:24:01 – are there legitimate benefits to the sugar diet?
It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: FDA approves the first fast-acting biosimilar insulin in the US, Tandem issues warning, DOJ stands up for remote monitoring in schools, GLP1 use protects against dementia, and more! Find out more about Moms' Night Out Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX We've got the first and only biosimilar FDA approved and moving to market. Kirsty – insulin aspart, which is a biosimilar to Novolog will be available as a single-patient-use prefilled pen for subcutaneous use and a multiple-dose vial for subcutaneous and intravenous use. KIRSTY has been available in Europe and Canada since 2022. This same company makes Semglee, the first biosimilar for long acting? Sales of Insulin Aspart in the United States were approximately $1.9 billion in 2024, according to IQVIA. https://www.globenewswire.com/news-release/2025/07/15/3115973/0/en/Biocon-Biologics-Expands-Diabetes-Portfolio-with-FDA-Approval-of-Kirsty-the-First-and-Only-Interchangeable-Rapid-Acting-Insulin-Aspart-in-the-United-States.html XX Tandem Diabetes Care (Nasdaq:TNDM) has issued an urgent medical device correction for some t:slim X2 automated insulin pumps. In a July 22 notice, the San Diego-based company warned of pumps that may exhibit a higher rate of speaker failure. During normal use, the insulin pump software monitors current flowing through the speaker during use. Measurements that fall within a pre-determined range indicate a functioning speaker. Meanwhile, measurements falling outside the range indicate a speaker failure. When the measurements land outside the expected range, the system declares a malfunction, referred to as “Malfunction 16.” If the pump declares this malfunction, insulin delivery will stop and the pump will no longer be operational. Malfunction 16 terminates communication between the pump and continuous glucose monitor (CGM), as well as the t:slim mobile app. If not addressed, the issue can lead to hyperglycemia, which can result in hospitalization or medical intervention. The company reports 700 adverse events and 59 reported injuries to date, with no reports of death. Tandem identified that certain speaker versions have a higher rate of Malfunction 16 events due to a wiring issue within the speaker. Users can continue using their pump but with added precautions because Malfunction 16 can occur at any time. They should use the t:slim mobile app with push notifications turned on so the app alerts them if the malfunction occurs, the company said. Additionally, Tandem intends to release a software update aimed at enhancing the early detection of speaker failure. The update also introduces persistent vibration alarms to help reduce potential safety risk. Tandem plans to notify affected pump users when it makes the update available. https://www.drugdeliverybusiness.com/tandem-warns-insulin-pump-speaker-malfunction/ XX BIG WIN! The DOJ protects T1D rights again! The US Attorney's office for the Western District of Washington State reached a settlement with a public school district that once again confirms remotely monitoring students' CGMs is a reasonable accommodation that schools must provide to comply with the Americans with Disabilities Act. If its true for one state its true for all states under federal law! If your local schools still refuse to remotely monitor CGMs of their students, provide them with this letter to compel them to FOLLOWT1Ds and FOLLOW Federal Laws. If they still refuse contact us! https://followt1ds.org/ XX new study finds people taking GLP-1 agonists had a significantly lower cumulative risk of developing dementia, when compared to metformin users. Past studies show that people who have type 2 diabetes — a chronic condition where the body does not use its insulin properly — are at a higher risk of developing dementia. The study found that when comparing the neuroprotective abilities of two diabetes medications — metformin and glucagon-like peptide-1 receptor agonists (GLP-1 agonists) — participants taking GLP-1 agonists had a significantly lower cumulative risk of developing dementia, when compared to metformin. https://www.medicalnewstoday.com/articles/glp-1s-may-offer-better-dementia-protection-than-metformin XX Front office changes coming to Dexcom. CEO Kevin Sayer will step down & give the reins to current Chief Operating Officer Jake Leach. Scheduled for January 1, 2026, Leach will also join Dexcom's board of directors where Sayer will remain executive chairman. One of our frequent guests here.. Leach has worked at Dexcom for 21 years. He served as chief technology officer from 2018 to 2022 before he was named COO in late 2022. He was given the title of president in May. https://www.medtechdive.com/news/dexcom-ceo-change-kevin-sayer-jake-leach/756382/ XX A major international study has revealed that many children and young adults in Sub-Saharan Africa who are diagnosed with type 1 diabetes (T1D) may actually have a different, non-immune-based form of the condition. Unlike the traditional autoimmune version of T1D, this form appears to develop without the immune system attacking the insulin-producing cells. This finding could significantly reshape how diabetes is diagnosed and treated across the region, potentially leading to more precise care and better health outcomes. The researchers found that many young people in Sub-Saharan Africa diagnosed with T1D often don't have the usual markers in their blood (called islet autoantibodies) typically seen in people with T1D in other parts of the world. Specifically, 65% of participants with T1D in this region did not have islet autoantibodies. When the researchers compared this data to studies in the U.S., they found a smaller but significant proportion (15%) of Black participants diagnosed with T1D had a similar form of diabetes found in Sub-Saharan Africa – characterized by negative autoantibodies and a low T1D genetic risk score. However, white Americans with T1D showed the typical autoimmune pattern, even if they didn't have detectable autoantibodies, their genetics still pointed to autoimmune diabetes. “The identification of this T1D diabetes subtype in Sub-Saharan African populations and among individuals of African ancestry in the U.S. suggests a potential ancestral or genetic link,” Dabelea notes. “These findings highlight the need to consider alternative etiologies in this group and a deeper understanding of the underlying mechanisms may provide important insights for future prevention and treatment strategies.” https://scitechdaily.com/new-diabetes-subtype-discovered-in-africa-challenges-global-assumptions/ XX Formal recognition for the specialty of Diabetology. Diabetology is the specialty focused on the full continuum of diabetes care — encompassing diagnosis, treatment, prevention, technology integration, education, and cardiometabolic management. While it intersects with endocrinology, primary care, and public health, diabetology is uniquely defined by its depth and focus on diabetes alone. The American College of Diabetology (ACD) is the national professional organization representing clinicians who specialize in diabetes care. ACD advances clinical excellence and education to improve the lives of those affected by diabetes. https://www.businesswire.com/news/home/20250725766248/en/American-College-of-Diabetology-Announces-Formal-Taxonomy-Classification-for-Diabetology XX Tidepool announces cloud-to-cloud integration with Abbott's FreeStyle Libre portfolio. From the release: This integration allows people living with diabetes using the FreeStyle Libre portfolio to connect their data to their Tidepool account seamlessly. For healthcare providers, this means more comprehensive insights and streamlined workflows, with FreeStyle Libre systems data flowing continuously into the Tidepool Data Platform. https://www.tidepool.org/blog/abbott-freestyle-libre-integration-launched XX Stelo dexom ai food XX With high drug prices remaining an ongoing concern for U.S. politicians, Roche is considering following in the footsteps of some of its peers with a direct-to-consumer (DTC) model to cut out the middlemen. About 50% of the money spent on drugs in the U.S. healthcare system goes straight to PBMs instead of the companies that create the medicines, Roche CEO Thomas Schinecker called out in a press conference on Thursday. Bringing the drugs directly to the consumer could be a solution to positively impact pricing for patients “without destroying innovation,” Schinecker added on a separate Thursday call with investors, noting that the company has discussed the matter with the U.S. government and its Department of Health and Human Services. The pricing talks come after President Donald Trump inked a “Most Favored Nation” executive order in May, aiming to tie U.S. drug prices to lower prices in other developed nations. The plan was quickly called out by industry voices such as the PhRMA trade group, which labeled it a “bad deal” for U.S. patients. https://www.fiercepharma.com/pharma/roche-weighing-direct-consumer-drug-sales-ease-us-drug-pricing-woes-cut-out-pbms-ceo-says XX SAB BIO secures substantial $175M financing to advance T1D therapy with impressive investor lineup and extended cash runway until 2028. Most critically, this financing fully funds the pivotal Phase 2b SAFEGUARD study evaluating SAB-142 for delaying progression of autoimmune Type 1 diabetes in newly diagnosed patients. By extending the cash runway into mid-2028, SAB has effectively eliminated near-term financing risk and provided clear visibility through this crucial clinical trial and potential commercialization preparation. Participation from strategic investor Sanofi, along with new investors RA Capital Management, Commodore Capital, Vivo Capital, Blackstone Multi-Asset Investing, Spruce Street Capital, Forge Life Science Partners and Woodline Partners LP, and existing investors Sessa Capital, the T1D Fund, and ATW Partners https://www.stocktitan.net/news/SABS/sab-bio-announces-oversubscribed-175-million-private-fwsf2t91ek4z.html XX In a landmark 14-year study, researchers have found that artificially sweetened drinks raise the risk of developing type 2 diabetes by more than a third, significantly higher than those loaded with sugar. It challenges the long-standing perception of diet drinks being a healthier alternative and suggests they may carry metabolic risks of their own. In the first longitudinal study of its kind, led by Monash University, researchers tracked 36,608 participants over an average period of 13.9 years to assess how both sugar-sweetened beverages (SSBs) and artificially sweetened beverages (ASBs) impacted health outcomes. The self-reported health data, from the Melbourne Collaborative Cohort Study, was drawn from participants aged 40 to 69 years at the time of recruitment. What they found was that drinking just one can of artificially sweetened soda increased the risk of developing type 2 diabetes by 38%, compared to people who didn't consume these drinks at all. For those consuming the same amount of sugary drinks, the risk was 23% higher. This suggests there's more than obesity at play. The researchers believe this result is due to an independent metabolic effect, possibly gut microbiome disruption or a change in glucose metabolism. While the study didn't identify which artificial sweeteners were at play, Evidence suggests that artificial sweeteners can alter the composition and function of gut bacteria, leading to glucose intolerance – a precursor to type 2 diabetes. And that some sweeteners may trigger insulin release, desensitize metabolic responses over time, or confuse the body's glucose regulation system – even without actual sugar in the picture. Another hypothesis is that regular exposure to the kind of intense sweetness that artificial products deliver may condition the body to anticipate sugar calories that never come, affecting appetite regulation, insulin sensitivity and broader metabolic pathways. However, the authors suggest that how sweeteners affect the gut microbiota and glucose regulation are the most likely drivers of increased diabetes risk. https://newatlas.com/diet-nutrition/one-drink-diabetes-risk/ XX After months of deliberation, information gathering and public testimony, a state board unanimously agreed Monday that two common medications for type-2 diabetes and other conditions appear to pose an affordability challenge to the state and Marylanders. The state Prescription Drug Affordability Board approved two resolutions saying that prescription drugs Jardiance and Farxiga likely pose an “an affordability challenge for the state health care system” and the state should look for ways to bring down those costs. Health care advocates call the long-awaited resolution an “important first step” in the process in bringing down prescription costs for those on the state's health plan. That milestone has been years in the making. Created in 2019 by the General Assembly, the Prescription Drug Affordability Board was slow to launch due in part to a veto from former Gov. Larry Hogan (R) amid pandemic-induced economic uncertainty in 2020 that delayed the board's formation. The board also cited out-of-pocket costs for consumers and state and local spending on those drugs as indicators that there may be an affordability challenge. The board will now look at options to address the potential affordability challenge, which could include setting an upper payment limit on those drugs. But it's not clear when the state will see cost savings. That said, some members of the health care system and the pharmaceutical industry say that policies such as upper payment limits could weaken access to life-saving drugs. Others say that the board has not engaged enough viewpoints from the health care industry. https://marylandmatters.org/2025/07/29/state-board-determines-two-type-2-diabetes-drugs-may-be-unaffordable/ XX One year after it was revealed that Chrissy Teigen and John Legend's son, Miles, was diagnosed with type 1 diabetes, Teigen is revealing how she's making her son feel more included. Teigen first opened up about her 7-year-old son's diagnosis after she and her two oldest kids, Miles and 9-year-old daughter Luna were at the 2024 summer Olympics cheering on Simone Biles. Teigen posted a photo of Miles and Luna holding up a sign. Also visible in the picture was the insulin pump on Miles' arm. Now, Teigen is sharing some insight into how she's making Miles more comfortable with having type 1 diabetes, including giving LeBron James' Barbie doll type 1 diabetes as well. In a video shared on Instagram, Teigen is seen taking the T1D Barbie, removing her insulin pump and gluing the pump onto LeBron James' Barbie. “Turning T1D Barbie into T1D Lebron James for my son,” Teigen captioned the video, revealing James is Miles' hero. 41 million followers https://www.yahoo.com/lifestyle/articles/chrissy-teigen-gives-lebron-james-154608782.html
"Why is it such a big deal for kids to get cars?" It's our contractually obligated sports media segment that Dan Le Batard is jealous of! Shannon Sharpe is out at ESPN, OJ Mayo's name is completely unfair to his brother, and Zaslow's kid can't stop singing the Jardiance jingle. Learn more about your ad choices. Visit podcastchoices.com/adchoices
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Episode 2676 - Vinnie Tortorich and Anna Vocino discuss recent traveling adventures, the risk of side effects with some medications, and more. https://vinnietortorich.com/2025/07/the-risk-of-side-effects-episode-2676 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH ALL THE PODCAST EPISODES ON YOUTUBE - The Risk of Side Effects Several of Vinnie's most recent expert guests want to discuss GLP-1s. Vinnie has said from the beginning that he didn't trust the long-term effects of using GLP-1s. (6:45) Studies show that up to 50% of the weight lost from use of GLP-1 can be muscle loss! Your body needs muscle mass to thrive! (15:00) People need to move to stay strong and agile. (16:00) The Western world is spoiled because of modern-day conveniences. Anna has been traveling and has found it hard to find clean food. (22:30) She shares her experience and how she's noticed that her taste buds have changed. Vinnie plays a commercial for Jardiance, and they deconstruct the side effects. (40:00) The drug doesn't tend to reverse Type 2 diabetes; however, eating the right foods can. You can purchase the NSNG® e-book for $10, and it will be beneficial if you follow the advice.(46:00) The VIP Group will be opening again soon, and the workout videos that Vinnie created will be available for FREE for members. (47:00) Vinnie recounts his visit back to his hometown and the conversations with friends in his age group, including the number of medications they were on. (54:00) Drug companies are heading towards being Trillion-dollar companies! More News If you are interested in the NSNG® VIP group, register here! Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! There's a new NSNG® Foods promo code you can use! The promo code ONLY works on the NSNG® Foods website, NOT on Amazon. https://nsngfoods.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere:
In the "Medicare Advantage Minute" we learn that some politicians have opined that MA plans might be overdue for an overhaul! Welcome to the party! The "Your Medicare Benefits 2025" segment teaches us how Medicare is likely to cover Mental Health & Substance Use Disorders. Are you worried about having a medical emergency while you are on vacation? I review an article that presents strategies for spending less while enjoying life more. Finally, a personal friend of mine had been paying $800 for quarterly refills of his expensive drug. On vacation in St. Maartin he acquired a refill for $230. After I gave him another source he reported his best result at $156 for a 90 day source. Maybe I can help you, too! Contact me at: DBJ@MLMMailbag.com (Most severe critic: A+) Visit us on: BabyBoomer.ORG Inspired by: "MEDICARE FOR THE LAZY MAN 2025; Simplest & Easiest Guide Ever!" "MEDICARE DRUG PLANS: A SIMPLE D-I-Y GUIDE" For sale on Amazon.com. After enjoying the books, please consider returning to leave a short customer review to help future readers. Official website: https://www.MedicareForTheLazyMan.com.
In this episode, Adam kicks off the show with a surprisingly deep dive into the symbolism and social dynamics of sandwich-making, unpacking how something so simple says a lot about parenting, care, and culture. He then calls out Dr. Drew's notoriously bad bedside manners and rants about people who constantly unload their health issues on him. Later, Adam takes aim at a bizarre Jardiance commercial, tearing into its absurd list of side effects.In the news, Adam reacts to President Biden's first comments after a recent cancer diagnosis and his attempt at humor regarding his mental competency. He questions whether Democrats prioritize gun control over illegal immigration, shares his thoughts on the recent Boulder, Colorado terror attack, and breaks down how mass immigration can influence culture.Finally, Mission Impossible stuntman-turned-actor Stephen Oyoung joins Adam in the studio to talk about his journey into Hollywood, working alongside Tom Cruise, and the crazy world of action filmmaking. They also discuss Asian representation in media, Stephen's SoCal upbringing, his love of martial arts, and how Loveline helped shape his early years. Get it on.FOR MORE WITH ELISHA KRAUSS: INSTAGRAM: @elishakraussWEBSITE: elishakrauss.com JOURNAL: https://www.washingtonexaminer.com/author/elisha-krauss/FOR MORE WITH STEPHEN OYOUNGINSTAGRAM: @stephenoyoungTWITTER: @mrstephenoyoungThank you for supporting our sponsors:BetOnlineHomeChef.com/ADAMHomes.comoreillyauto.com/ADAMPluto.tvRosettastone.com/ADAMRuffGreens.com - Use promo code “Adam”SIMPLISAFE.COM/ADAMLIVE SHOWS: June 11 - Palm Springs, CAJune 13 - Salt Lake City, UT (2 shows)June 14 - Salt Lake City, UT (2 shows)June 19 - Las Vegas, NV (2 shows)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Federal employee rights will change in the Trump-backed budget legislation “One Big Beautiful Bill.” Will budget-busting drugs like Jardiance and Farxiga soon cost less in Maryland? A new law sets up a mechanism. The state is fixing to charge for viewing land records and the Maryland State Bar and title attorneys are not happy. In Frederick County, MD, a fake mooning incident at a school board meeting. We have the audio, which may be more incendiary than the video. And more. Music by Arlington-based experimental music composer Pierre Bernasconi.
Shenanigans are really swell, stupid banter and a big story to tell (Side effects of Shenanigans include questioning the choices in your life). This week's show gives the sweet and talented Deanna Colón. This singer and entertainer has performed with and for Diana Ross and Patti Labelle, been on America's Got Talent & Masterchef, and been in commercials like Bad Bunny's Pepsi ad and the Jardiance jingle. We get to learn about who the “Bomb Chica” is and hear about her life. We go off the rails as always and discuss Mike's signature dish, whether or not we'd go to space, and Scott tells a a cray story about one of the worst intro's in comedy show history. Have a listen!
Episode 2623: Vinnie Tortorich and Chris Shaffer discuss news items that address junk food in the SNAP program, weight loss drug risks, and more. https://vinnietortorich.com/2025/03/weight-loss-drug-risks-episode-2623 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH ALL THE PODCAST EPISODES ON YOUTUBE - Weight Loss Drug Risks Several states are trying to ban junk foods from being purchased from the SNAP program. (10:00) Each state defines junk food differently, but many define it as soda and candy. (13:30) The focus is trying to get people to purchase whole foods. The American Heart Association is pushing back against this move. (21:00) The various reasons the AHA gives are discussed and not all of them make sense. Vinnie and Chris review the list of companies and how much they contribute to the AHA each year. (28:15) One excuse claims the number of products is “just too hard” to list. The UK is now banning ads for junk food. (35:45) They discuss the drug Jardiance and the health disclaimers at the end of the ad. (38:00) Next in the discussion is Zepbound, which was used for sleep apnea, but is also marketed as a weight loss drug. (47:30) Vinnie emphasizes that going low-carb will give you none of the side effects that the medications will have. More News If you are interested in the NSNG® VIP group, closed for registration, but you can get on the wait list - Don't forget to check out Serena Scott Thomas on Days Of Our Lives on the Peacock channel. “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook is available! You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! Don't forget you can invest in Anna's Eat Happy Kitchen through StartEngine. Details are at Eat Happy Kitchen. There's a new NSNG® Foods promo code you can use! The promo code ONLY works on the NSNG® Foods website, NOT on Amazon. https://nsngfoods.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere:
This week we are joined by Deanna Colon! Deanna is a singer, songwriter, actress, vocal coach, and chef. Deanna was a contestant on Season 8 of NBC's #1 rated show, “America's Got Talent”, making it to the live, quarter semifinal round at Radio City Music Hall in NYC. She was also the lead singer/dancer/actress for 2 years of BIG LOTS holiday commercials.Deanna has sung background vocals for many recording artists, including Nick Jonas, Celine Dion, Lea Michele, Justin Bieber, and Paula Abdul. On Season 10 of the FOX show Master Chef, Deanna won a coveted white apron from the judges and became a member of the elite Top 20. She also has garnered almost 300K followers on her Tik Tok cooking show “Fork My Life”. In 2023, Deanna was cast as the lead singer/actress/dancer in a huge national spot for pharmaceutical brand Jardiance. Make sure to check her out!In this episode, Deanna shares her multifaceted journey through the culinary and entertainment worlds. Deanna reflects on her upbringing in a family restaurant, the importance of travel and life experiences, and her discovery of a talent for singing that led her to a scholarship at Berklee College of Music. We share starstruck moments with music legends, reflect on the complexities of fame and personal safety, and discuss the reality of competition shows in the entertainment industry. Deanna discusses the importance of versatility in creative careers, her personal experiences with body image and acceptance, and the comfort food that brings her joy. Deanna also emphasizes the need for self-love and the challenges of being an outsider, while also highlighting her passion for cooking and connecting with others through food. Give this episode a listen!Recommendations From This Episode: WildCard KitchenMystic PizzaFollow Deanna Colon: @deannabombchica on Instagram and TikTokFollow Carly: @carlyjmontagFollow Emily: @thefunnywalshFollow the podcast: @aloneatlunchpodPlease rate and review the podcast! Spread the word! Tell your friends! Email us: aloneatlunch@gmail.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Ellen Kamhi talks with Dr. Swathi Varanasi-Diaz, an award-winning healthcare professional recognized for her trailblazing work at the forefront of personalized medicine and healthcare innovation. She earned her Doctor of Pharmacy from the Medical University of South Carolina and became the first pharmacist in the U.S. to complete a postdoctoral residency in integrative medicine and preventive health. Following this achievement, she co-founded the Integrative Health Pharmacy Residency Program. Her credentials also include a postdoctoral fellowship in biotech and nutrition from Cornell University. Her research has been published in peer-reviewed academic journals and she has served as faculty and guest lecturer at numerous academic institutions. In 2023, was honored as one of 50 Most Influential Leaders in Pharmacy. https://myosmd.com/
Welcome to the 45th episode of my drug pronunciation series! As we continue through the alphabet from A-Z, we're on the letter “E” for empagliflozin. Also check out episode 228 for ezetimibe and episode 134 for eszopiclone. In this episode, I break down empagliflozin and Jardiance into syllables, tell you which syllables to emphasize, and share my sources. The written pronunciations are helpful. They are below
Max gets ready for the big live show by doing some breathing exercises with Roger and talking through the show agenda on Wednesday, September 11th, 2024.LIVE SHOW IS TONIGHT AT 7PM AT CAVEAT NYC!!https://www.caveat.nyc/events/sports-talk-right-now-9-11-2024 Hosted on Acast. See acast.com/privacy for more information.
On today's MJ Morning Show: 'America's Cobbler' had a heart attack Buc-ees car wash Morons in the news Doctors warn of 'carnivore diet' (sounds to us like Atkins diet) A psych hospital isn't releasing patients? What is 'chroming'? 'The Babadook' MJ's October flight got changed... and more than he realized (it's fun to hear him get angry) Teacher put a 3-year-old in a headlock MJ has more rice cookers to give away Jardiance ad for Fester? You may unintentionally offend someone by wearing this... we took lots of calls Marketing firm admits to listening to people through their phones Trial date set for the Ketamine Queen Someone just signed on for a podcast... Okay, it was the 'Hawk Tuah' girl '1,000 lbs Sisters' sister arrested after being bitten by a camel... Um... what? Travis Kelce angry about fake contract Backlash against Capri Sun How much does Scottie Scheffler's caddy earn? Doctor tells patient she has a short life expectancy after seeing this Brian May of Queen lost use of his arm because of a stroke... but he's feeling much better, now... Rachael Ray fans concerned after her latest video Tip to law enforcement officers... don't leave your firearm in a Racetrac bathroom Intersection takeover arrests America's Cobbler, Jim McFarland, spoke to MJ Railing on Titanic isn't safe Fan knocked out at Tampa Bay Rays game by a home run ball Video of a Pepsi van barely getting across train tracks to avoid becoming scrap metal Car crashes through a Phoenix home, narrowly missing couple and their dogs
Can a simple lifestyle change reduce healthcare costs and improve patient outcomes without adding a cent to the budget? In this week's Crazy Medical Story on The Independent Physician's Blueprint, we explore a groundbreaking approach that could revolutionize the treatment of diabetes.In a recent study published by JAMA's Network Open Access, intermittent fasting outperformed standard medications like Jardiance and Metformin in controlling blood sugar levels. Coach JPMD shares his personal experience with intermittent fasting and its transformative effects on his energy and health. Discover how this underutilized strategy could be a game-changer for your patients and practice.Listen to learn how incorporating intermittent fasting into your medical practice can not only help manage diabetes more effectively but also reduce reliance on costly medications. This episode provides insights into a practical, evidence-based approach to improving patient outcomes without breaking the bank.Ready to rethink your approach to diabetes management? Tune in now and start implementing these life-changing strategies in your practice today!Reference: Guo L, Xi Y, Jin W, et al. A 5:2 Intermittent Fasting Meal Replacement Diet and Glycemic Control for Adults With Diabetes: The EARLY Randomized Clinical Trial. JAMA Netw Open. 2024;7(6):e2416786. doi:10.1001/jamanetworkopen.2024.16786Dr.Mindy Pelz - "Fast Like a Girl" https://drmindypelz.com/ Discover how medical graduates, junior doctors, and young physicians can navigate residency training programs, surgical residency, and locum tenens to increase income, enjoy independent practice, decrease stress, achieve financial freedom, and retire early, while maintaining patient satisfaction and exploring physician side gigs to tackle medical school loans.
DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE! In today's episode of the "Fasting for Life" podcast, we discuss the use of intermittent fasting as a lifestyle intervention for managing and potentially reversing type 2 diabetes. We highlight a recent study comparing the outcomes of a 5:2 meal replacement fasting group to those on metformin or Jardiance, demonstrating superior results in the fasting group for glucose control, weight loss, and reduced side effects. The practical takeaway is emphasizing small, manageable lifestyle changes rather than extreme measures to achieve sustainable health improvements. We encourage listeners to consider integrating intermittent fasting and deliberate meal choices into their lives for long-term wellness benefits. FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! Learn how to RAMP UP into longer fasting windows! Gain insights into the non-weight loss benefits of fasting! Personalize your own fasting schedule and consistent FAT LOSS results! Get answers to what breaks a fast, how to break a fast, and tips and tricks to accelerate your fasting wins! THE BLUEPRINT TO FASTING FOR FAT LOSS DOWNLOAD Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! Fasting For Life Community - Join HERE New to the podcast and wondering where to start? Head to the website and download our Fast Start Guide, 6 simple steps to put One Meal a Day Fasting (OMAD) into practice! Get our NEW sleep guide here! SLEEP GUIDE DIRECT DOWNLOAD If you enjoy the podcast, would you please tap on the stars below and consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Research Links:
It's In the News! A look at the top diabetes stories and headlines happening now. Top stories this week: A new study looks at insulin needs in men vs women, updates on stem cell transplants and a new look at COVID 19 and T1D plus a fully implantable CGM is announced. We'll also tell you about a T1D athlete drafted to the MLB. Lots more in this week's episode, full transcipt below. Find out more about Moms' Night Out Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Edgepark Medical Supplies Check out VIVI Cap to protect your insulin from extreme temperatures Learn more about AG1 from Athletic Greens Drive research that matters through the T1D Exchange The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX In the news is brought to you by Edgepark simplify your diabetes journey with Edgepark XX Do men and women have different insulin requirements? A new study conducted across Europe says yes – women overall need less. Published in the Journal of Diabetes Science and Technology this looked at over 9,000 adults with type 1 diabetes using data from patients using the Diabeloop Generation 1 (DBLG1) hybrid closed-loop pump system. In this study, women needed 14-percent less insulin overall than men. These researchers say these findings have important implications for the practical management of insulin therapy and highlight the necessity of considering gender as a crucial factor in diabetes treatment. The treatment guidelines provided by American and European Diabetes Societies do not currently have gender-specific recommendations for insulin-weight ratios. The co-founder and Chief Scientific and Technical Officer for Diabeloop. “This study also highlights the capacity to discover new insights from big-data analysis of real-world data.” *Insulin Requirements According to Gender and Weight in a Population of 9036 Adult Persons With Type 1 Diabetes Using Closed-Loop Insulin Delivery, https://doi.org/10.1177/19322968241252366). https://www.theglobeandmail.com/investing/markets/markets-news/GetNews/27419187/diabeloop-study-reveals-significative-gender-differences-in-insulin-requirements-for-type-1-diabetes-patients/ XX New drug therapy in those lucky diabetic mice boosted insulin-producing cells by 700% over three months, effectively reversing the disease. Scientists at Mount Sinai and City of Hope have been able to grow new beta cells in the body, in a matter of months. The therapy involved a combination of two drugs: one is harmine, a natural molecule found in certain plants, which works to inhibit an enzyme called DYRK1A found in beta cells. The second is a GLP1 receptor agonist. The latter is a class of diabetes drug that includes Ozempic, The researchers tested the therapy in mouse models of type 1 and 2 diabetes.. The signs of the disease quickly reversed, and stayed that way even a month after stopping the treatment. The results are intriguing, but of course being an animal study means there's still much more work to be done before it could find clinical use. So far, harmine alone has recently undergone a phase 1 clinical trial in humans to test its safety and tolerability, while other DYRK1A inhibitors are planned for trials in humans next year. https://newatlas.com/medical/diabetes-reversing-drug-boosts-insulin-producing-cells/ XX Stem cell–derived beta-cell replacement therapy continues to show benefit in people with type 1 diabetes at a high risk for severe hypoglycemia. New info from Vertex shows that of a total 17 patients who received a full dose of their investigational allogeneic stem cell–derived, fully differentiated pancreatic islet cell replacement therapy (VX-880), three, thus far, have achieved the primary study efficacy endpoint of elimination of severe hypoglycemic episodes with A1c < 7% at 1 year and the secondary endpoint of insulin independence. Others are on the same trajectory, Piotr Witkowski, MD, PhD, professor of surgery at The University of Chicago, Chicago, said at the recent American Diabetes Association (ADA) 84th Scientific Sessions. In his presentation, Witkowski also provided details about the deaths of two study participants that the company had announced in January 2024, neither of which were related to the VX-880 product. In fact, there have been no severe adverse events related to the product itself, with most due to either the infusion procedure or the immunosuppression. "These data highlight the curative potential of VX-880 in people living with type 1 diabetes and support further evaluation of VX-880 toward pivotal development," Witkowski said. For now, patients selected for the study are those who experience frequent severe hypoglycemia deemed to be a greater risk to the patient than that of immunosuppression. However, Ahn pointed out, "With VX-880, the obvious fly in the ointment is the need for immunosuppression which carries significant risk…There are multiple solutions being proposed, but we are still waiting for data as promising as the initial Vertex data is on that front." https://www.medscape.com/viewarticle/stem-cell-derived-islets-continue-show-benefit-t1d-2024a1000cx1 XX Still lots of COVID studies coming in about type 1. A German study suggests COVID 19 may speed up progression of existing but presymptomatic T1D in kids. These researchers had been screening and following children in an early presymptomatic stage of type 1 diabetes for several years. They noticed an increase in the numbers of Incidence of clinical type 1 diabetes nearly doubled after the pandemic started. "We know that the virus can infect the pancreatic islets so it could be causing damage or change in the beta cells that make insulin," said Ziegler when discussing possible mechanisms behind this association. "Second, there is generalized inflammation during the infection and there may be a stimulation of the immune response. Third, there could be metabolic stress from the infection that affects the beta cells that make insulin. To dive into this topic, youth were identified in the German Fr1da-screening program from 2015 to 2023. All patients had presymptomatic diabetes defined as persistent, confirmed positive results for two or more islet autoantibodies. Their progression was monitored at 3- to 6-month intervals. Clinical type 1 diabetes was defined according to American Diabetes Association COVID infection was either self-reported via the family or identified with SARS-CoV-2 antibodies were confirmed in blood samples collected at study visits. Vaccination against COVID-19 may be one way to protect presymptomatic type 1 diabetes youth from progression, Ziegler added. She said her group is currently testing whether COVID-19 vaccination can reduce new-onset, presymptomatic type 1 diabetes in a clinical trial of children with genetic risk factors for the condition. https://www.medpagetoday.com/endocrinology/type1diabetes/111084 XX The FDA says no – for now - to Novo Nordisk's weekly insulin. This has been approved in Canada and should be available there shortly. But the FDA says it wants more information related to the manufacturing process and the type 1 diabetes indication to complete the review. Novo said it does not expect to be able to fulfil the requests this year, and that it will work closely with the FDA regarding the next steps. The regulator's decision follows its outside panel's vote against the use of the weekly insulin icodec, in patients with type 1 diabetes due to risks of low blood sugar. https://www.reuters.com/business/healthcare-pharmaceuticals/us-fda-declines-approve-novo-nordisks-weekly-insulin-2024-07-10/ XX A couple of weeks ago we spoke to the attorneys taking on CGM monitronig in schools. They've helped a family in Connecticut and set a precdent. A child with autism and diabetes was not getting reasonable accommodations under the federal Americans with Disabilities Act in a public preschool program. I'll link up the press release from the DOJ but this family wasn't getting any support and it just wasn't safe. The lawyers here tell me the ruling and settlement is just going to help them going forward as they try to make schools complient with CGM as a reasonable accomodatin. https://www.justice.gov/usao-ct/pr/aba-therapy-provider-make-changes-comply-americans-disabilities-act XX Ozempic could lower the risk of dementia and a range of other mental problems compared with other existing treatments for patients with diabetes. What's more, researchers found that Ozempic cut nicotine dependence in those patients. This study relied on medical records from more than 100,000 U.S. diabetes patients, including more than 20,000 who were prescribed semaglutide between December 2017 and May 2021. After a year, patients who took Ozempic had a 48% lower risk of developing dementia than those on Januvia. The risk in Ozempic patients was also 37% lower than those who took Glucotrol and 9% lower than those on Jardiance. Notably, previous research has determined that diabetes patients are at a greater risk of developing dementia. But the authors emphasized that the analysis is observational. The results need to be replicated in a controlled trial that assigns patients to randomly take Ozempic and the other drugs, according to Dr. Max Taquet, another Oxford clinical lecturer and senior study author. https://www.cnbc.com/2024/07/16/healthy-returns-ozempic-may-lower-dementia-risk-nicotine-use.html XX Edgepark Commercial XX The Omnipod 5 with Dexcom G7 integration is now available through select pharmacies with full availability expected in the fall. The System uses new Pods that are compatible with both Dexcom G6 and G7, but the prescription code will stay the same as the current Omnipod 5 Pods. This means the community will have similar insurance coverage and access to what they have with Omnipod 5 today. If you're looking to start on Omnipod 5 and you're currently using Dexcom G7, your doctor will need to send a prescription for both the Omnipod 5 Intro Kit and Omnipod 5 Pods, compatible with Dexcom G6-G7, to ASPN Pharmacies. You can learn more at https://www.omnipod.com/innovation/dexcom-g7. If you are already using Omnipod 5, you will get the new Pods compatible with Dexcom G6 and G7 through your Pod refills. You do not need a new prescription. The week of July 29th, you will receive a free software update for the Omnipod 5 App to your Controller or compatible Android smartphone which is needed to use the System with Dexcom G7. Accept the update. We recommend you continue to use your current Omnipod 5 Pods and Dexcom G6 supplies until the new Pods compatible with Omnipod 5 with Dexcom G6-G7 are available at your preferred pharmacy. We'll email our users when the new Pods are available in most pharmacies. You can learn more at https://www.omnipod.com/innovation/new-compatible-devices XX Big promises about long-term implantable blood glucose monitor from a company called Focus. They say they're partnering with Glucotrack to quote - transform how people with diabetes interact with their condition. They're not calling this a CGM – rather it's a CBGM, continuous blood glucose monitor because it will measure glucose levels in blood, not in interstital fluid like CGMs do. They company says this is a fully subdermal location, with no external wearable. In preclinical studies, the CBGM has a MARD of 4.7% at day 90. That is MUCH lower than CGMs on the market – Dexcom and Libre are in the low 8s right now. BUT.. it hasn't been fully tested in people yet. Human clinical trials are set to start later this year. https://www.drugdeliverybusiness.com/focus-collaborates-glucotrack-implantable-cbgm/ XX Big congrats to Jamie Ferrer (Chy-may Fer-rare) On Monday, Ferrer's dream was realized when the Twins selected the Florida State outfielder in the fourth round (No. 126 overall) during Day 2 of the MLB Draft. Minnesota vice president of amateur scouting Sean Johnson said the club had its eyes on Ferrer since high school. “Recently, I was in Orlando at a conference called, “Friends for Life with CWD [Children with Diabetes],” and we had an event that was a sports day. … Kids would come up to me and either them or their families would ask me how I dealt with this [or that],” Ferrer said. “And seeing their faces light up whenever I said I was diagnosed at three and I played college baseball. … You hear people tell you no and that you can't do this because you have Type 1 diabetes … So why not inspire as many people as I can?” “I'm super proud of being a Type 1 athlete, and it's something that I'll never shy away from talking about or showing off my insulin pump because it's who I am and it's something that I've had to deal with my entire life.” https://www.mlb.com/news/jaime-ferrer-selected-no-126-overall-by-twins-in-2024-mlb-draft XX Join us again soon!
This episode has everything: curdled milk, tiny hats, the Tour de France, Big Gretch. And that's all before the break! In our SECOND segment, we explore our favorite topic of the week: ads.Move over Don Draper, because these two BBWs are coming through to serve up some of the best commercial moments you've ever heard. NOTHING helps ease the discomfort of humanity's agonizing downward spiral like a catchy little jingle! We learn about Lindy's legacy status in the advertising world and share some of the most iconic line reads from our favorite commercials (Robert Loggia???). Email us at deartextmeback@gmail.com to share what ads live rent-free in your brainestrone!Check out these (currently un-sponsored) faves!For amazing ice cream recipes, The Perfect Scoop by David LebovitzBrown Sugar-Bourbon Ice Cream by Bon AppetitGet into Cycling with us and watch the Tour de France on PeacockEnjoy Lindy's shoutout by THEE Big Gretch!And of course, go listen to ep where Lindy and Meagan wax poetic about the Jardiance commercial: Lindy and Meagan Corner the Husband Demographic⋆。°✩⋆。°✩⋆。°✩⋆。°If you like this episode and want us to keep making the show forever, please subscribe to our Patreon. This podcast will always be free, but we need your help to produce it -- and if you support our Patreon, you'll get all kinds of goodies in addition to the show itself! Learn more about the different tiers and rewards here: https://www.patreon.com/TextMeBackPodAlso! Please keep in touch with us! You can text OR CALL us at the Best Friend Party Phone: (703) 829-0003.We're on Instagram at @textmebackpod!Full videos of our episodes are on YouTube at @textlindyandmeaganbackYou can email us at deartextmeback@gmail.com!WE WANT TO HEAR FROM YOU SO BAD!⋆。°✩⋆。°✩⋆。°✩⋆。°TEXT ME BACK is a production of Lindy West and Meagan Hatcher-Mays, proud members of the BFF Network. Our senior producer is Meagan Hatcher-Mays. Our other senior producer is Lindy West. Our show is supported by COPILOT Collective and produced by Alli Slice.Our music is by Chief Ahamefule J. Oluo. Diana Bowen is our video and creative advisor. Our digital strategist is Chance Nichols.You can also follow the podcast on Instagram and TikTok @textmebackpod. And for even more bestie content, follow Lindy and Meagan on Instagram at @thelindywest and @importantmeagan!Special thanks as always to our perfect angels: Jeannie Yandel, Brandi Fullwood, and Isolde Raftery.⋆。°✩⋆。°✩⋆。°✩⋆。°See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
What will we pay for the next groundbreaking drug? In episode 4 of our 5-episode series, “Insight Unpacked: American Healthcare and Its Web of Misaligned Incentives,” we explore the trade-off at the heart of pharmaceutical innovation. On this episode, we hear from Kellogg faculty members Amanda Starc and Craig Garthwaite, as well as Boston University School of Law's Kevin Outterson. Visit the episode page for supplementary materials.
In hour two of A Numbers Game, Gill Alexander and Kelley Bydlon are joined by Chris Fallica to talk about today's Euro 2024 and Copa America matches, Deanna Colon joins to talk about her Jardiance commercial success and more, and Jason Weingarten joins to give out his best bets for today's MLB slate.See omnystudio.com/listener for privacy information.
In hour two of A Numbers Game, Gill Alexander and Kelley Bydlon are joined by Chris Fallica to talk about today's Euro 2024 and Copa America matches, Deanna Colon joins to talk about her Jardiance commercial success and more, and Jason Weingarten joins to give out his best bets for today's MLB slate.See omnystudio.com/listener for privacy information.
This week we are proud to report that we have a husband listener! Welcome, buddy! And what a time to be a new listener and/or a husband, because in this episode Lindy and Meagan are doing the Lord's work: ranking dragons. We're talking about Smaug. We're talking about Puff. We're talking about…the other ones.BUT THEN, as if that wasn't enough, Lindy and Meagan bravely breach a topic few have dedicated so much air time to. It's a little something with a big story to tell, it's the must-have accessory for your high A1C, it's an ear worm even mightier than the one in RFK Jr.'s brain. It's the Jardiance jingle, and in case you were wondering: yes, we play it in its entirety.If YOU are a husband who listens to the show, we want to hear from your wife! Let her know how much you love the show, and have her text or call us at the Best Friend Party Phone: (703) 829-0003.⋆。°✩⋆。°✩⋆。°✩⋆。°If you like this episode and want us to keep making the show forever, please subscribe to our Patreon. This podcast will always be free, but we need your help to produce it -- and if you support our Patreon, you'll get all kinds of goodies in addition to the show itself! Learn more about the different tiers and rewards here: https://www.patreon.com/TextMeBackPodAlso! Please keep in touch with us! You can text OR CALL us at the Best Friend Party Phone: (703) 829-0003.We're on Instagram at @textmebackpod!Full videos of our episodes are on YouTube at @textlindyandmeaganbackYou can email us at deartextmeback@gmail.com!WE WANT TO HEAR FROM YOU SO BAD!⋆。°✩⋆。°✩⋆。°✩⋆。°TEXT ME BACK is a production of Lindy West and Meagan Hatcher-Mays, proud members of the BFF Network. Our senior producer is Meagan Hatcher-Mays. Our other senior producer is Lindy West. Our show is supported by COPILOT Collective and produced by Alli Slice.Our music is by Chief Ahamefule J. Oluo. Diana Bowen is our video and creative advisor. Our digital strategist is Chance Nichols.You can also follow the podcast on Instagram and TikTok @textmebackpod. And for even more bestie content, follow Lindy and Meagan on Instagram at @thelindywest and @importantmeagan!Special thanks as always to our perfect angels: Jeannie Yandel, Brandi Fullwood, and Isolde Raftery.⋆。°✩⋆。°✩⋆。°✩⋆。°See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Garry discusses a recent interview with one of the cast members of the Jardiance commercial. Plus, the former home of Paul Reubens is for sale.
Resources for the Community:https://www.ivimhealth.com/weightloss/ Telehealth for weight management________________________________________________________________________joinfridays.comUe code PLUS10 to save________________________________________________________________________https://joinweightcare.com/products/s...https://joinweightcare.com/products/t...The Plus SideZ subscribers get $300 off monthly Semaglutide and Tirzepatide programs with coupon code - PLUSSIDEZ. And $100 off our 3-month Semaglutide and Tirzepatide programs with coupon code - PLUSSIDEZ3.________________________________________________________________________In this episode, we chat with a community member, Deanna "BombChica" Colon about her struggles with obesity and working with a trainer that had their own obesity bias. She lent her voice for the Jardiance commercial and faced much online bullying. We cover the traumas of being obese in a “slim” world and connect over mutual obesity experiences from living in a larger body. We also chatted with Dr Weiss, a board certified obesity specialist that co founded Fridays, an obesity medicine tele-health company. The team covers obesity bias in medicine, the future of obesity treatment, and predict changes in practice used to determine health (such as BMI). ________________________________________________________________________⭐️Mounjaro Stanley⭐️griffintumblerco.Etsy.comUse code PODCAST10 for $ OFF________________________________________________________________________________________________________________________________________________#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP #GLP1 #Obesity#ObesitySupport the showKim Carlos @DMFKimonMounjaro on TikTokJernine Trott @TheeJernine on TikTokKat Carter @KatCarter7 on TikTokLydia Roberts @UnapologeticallyNapster on TikTok
In past episodes of this podcast, we've discussed disparities in healthcare. We've looked at evidence that shows members of historically underserved communities who are living with MS can face a more severe disease course. We've looked at studies that have shown some members of these racial and ethnic minority groups don't do as well on disease-modifying therapies, and their MS progresses more quickly. It's often been speculated that the reason behind these disparities is based on genetics -- that members of minority communities who are living with MS are genetically predisposed to experiencing a more severe disease course. My guest in this episode is Dr. Annette Langer-Gould, and Dr. Langer-Gould comes armed with evidence that points to a completely different set of answers for the cause of racial and ethnic disparities in MS disease severity and progression. We're also sharing registration details for the National MS Society's MS Activist Rally on April 25th! We'll tell you about an inverse vaccine that prevents the mouse model of MS (and we'll explain what an inverse vaccine is!) You'll find out where you can find the just-released video progress report from the International Progressive MS Alliance. We'll explain just-published results from an analysis that shows why anti-diabetic and weight-loss drugs like Ozempic, Jardiance, and Trulicity may be repurposed as MS therapies. And we're sharing study results with both good news and not so great news when it comes to being diagnosed and treated for MS in a timely manner. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: We're exploring the reason that members of underserved minority populations who are living with MS often experience a more severe disease course :22 The MS Activist Rally is happening on 4/25! 1:28 An inverse vaccine prevents the mouse model of MS 3:49 The International Progressive MS Alliance has released their 2024 progress report 6:13 Can weight-loss drugs be repurposed as MS therapies? 7:33 A study shows that getting diagnosed and treated for MS is dependent upon your country's healthcare system 10:26 Dr. Annette Langer-Gould has a sobering answer as to why some members of minority communities who are living with MS experience a more severe disease course 14:48 Share this episode 31:31 Have you downloaded the free RealTalk MS app? 31:51 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/346 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com REGISTER for the MS Activist Rally https://events.zoom.us/ev/Ame2jWSuHmriG94cyQmlWHr45mgnzxkDv8oMZRGsrS3ZxiSj5rro~Anqb3dHg3ewiz4KNHn2Ena4bgli_WXlza_zcygZN3GinnleB6rO15OCzGQ VIDEO: International Progressive MS Alliance 2024 Progress Report https://www.youtube.com/watch?v=4ojRaLp_J1w STUDY: Exploring the Association Between Weight Loss-Inducing Medications and Multiple Sclerosis: Insights from the FDA Adverse Event Reporting System Database https://journals.sagepub.com/doi/10.1177/17562864241241383 STUDY: Disease-Modifying Therapy Initiation Patterns in Multiple Sclerosis in Three Large Populations https://journals.sagepub.com/doi/10.1177/17562864241233044 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 346 Guest: Dr. Annette Langer-Gould Privacy Policy
Resources for the Community:https://www.ivimhealth.com/weightloss/ Telehealth for weight management________________________________________________________________________joinfridays.comUe code PLUS10 to save________________________________________________________________________https://joinweightcare.com/products/s...https://joinweightcare.com/products/t...The Plus SideZ subscribers get $300 off monthly Semaglutide and Tirzepatide programs with coupon code - PLUSSIDEZ. And $100 off our 3-month Semaglutide and Tirzepatide programs with coupon code - PLUSSIDEZ3.________________________________________________________________________In this episode, we chat with a community member, Deanna "BombChica" Colon about her struggles with obesity and working with a trainer that had their own obesity bias. She lent her voice for the Jardiance commercial and faced much online bullying. We cover the traumas of being obese in a “slim” world and connect over mutual obesity experiences from living in a larger body. We also chatted with Dr Weiss, a board certified obesity specialist that co founded Fridays, an obesity medicine tele-health company. The team covers obesity bias in medicine, the future of obesity treatment, and predict changes in practice used to determine health (such as BMI). ________________________________________________________________________⭐️Mounjaro Stanley⭐️griffintumblerco.Etsy.comUse code PODCAST10 for $ OFF________________________________________________________________________________________________________________________________________________#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP #GLP1 #Obesity #ObesitySupport the showKim Carlos @DMFKimonMounjaro on TikTokJernine Trott @TheeJernine on TikTokKat Carter @KatCarter7 on TikTokLydia Roberts @UnapologeticallyNapster on TikTok
Leor is an endocrinology fellow and he sees patients with diabetes, among other metabolic diseases associated with insulin resistance. He thinks the mainstream approach to dietary recommendations can actually serve as a barrier to improvement for some patients. Timestamps: 00:00 Trailer. 00:50 Introduction. 05:28 Insulin resistance medical and lifestyle challenges. 09:32 Insulin resistance linked to cardiovascular disease risk. 12:26 USDA promoting processed foods, overeating. 14:53 Individualized approach for managing hypoglycemia risk. 18:44 Improved health through carnivore diet and mindful eating. 19:57 Hesitant about recommending red meat in diets. 25:03 Research studies on carnivore diet and diabetes. 26:32 Thyroid affects cholesterol levels; replacement therapy. 28:59 Carnivore diet may help reduce autoimmune symptoms. 32:27 Jardiance trial shows reduced cardiovascular events, increased LDL. 36:11 Encouraging healthy eating over medications for weight loss. 38:42 Does eating stimulate heart rate like drug? 41:41 Plant-based approach. 45:43 Dietary advice from dietitians. 47:58 Reducing medications. 50:25 Where to find Leor. See open positions at Revero: https://jobs.lever.co/Revero/ Join Carnivore Diet for a free 30 day trial: https://carnivore.diet/join/ Carnivore Shirts: https://merch.carnivore.diet Subscribe to our Newsletter: https://carnivore.diet/subscribe/ . #revero #shawnbaker #Carnivorediet #MeatHeals #HealthCreation #humanfood #AnimalBased #ZeroCarb #DietCoach #FatAdapted #Carnivore #sugarfree
Dave Dameshek (ESPN and Extra Points podcast) joins Jason and Randy to discuss the NFL's Wild Card Weekend, Steelers football, Jardiance commercials, the Dallas Cowboys failing again, Bellichick's future, Tony Dungy trying to bring Jesus to Taylor Swift, Jimmy Butler's music career, Russell Westbrook challenging fans to fight, James Dolan allegedly trafficking a masseuse to Harvey Weinstein, and Jerry Jones (Chris Cox) calls in to talk about the Cowboys future, and so much more!