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Dr. Hoffman continues his conversation with Dr. Sharad Paul, author of "Biohacking Your Genes: 25 Laws for a Smarter, Healthier, and Longer Life."
In this episode of the Intelligent Medicine Podcast, Dr. Ronald Hoffman interviews Dr. Sharad Paul, a New Zealand physician, on his book, "Biohacking Your Genes: 25 Laws for a Smarter, Healthier, and Longer Life." They discuss how genes serve as a blueprint but not a destiny, stressing the role of lifestyle and habits in managing genetic risks. Dr. Paul expands on the impact of diet, supplements, and exercise tailored to genetic makeup, citing his holistic approach versus extreme gene-editing biohacking. The conversation touches on vitamin D's role in health, the misconception about sun exposure, and the relationship between genetics and skin health. Nutrigenomics is explored, illustrating how genetic testing can influence dietary and lifestyle choices, while also covering genetic predispositions related to mood, sodium, and sugar sensitivity. The podcast concludes with actionable tips for optimizing skin health through diet and protective measures.
Broken heart syndrome, which is left ventricular dysfunction in the absence of coronary artery disease, is so-called because it can be triggered by extreme stress, such as loss of a loved one. Stress can also, in people with existing disease, trigger an acute coronary event and exacerbate arrhythmias.In this episode, the MIMS Learning editors Dawn Liz Powell and Rhiannon Ashman review how stress — both in the short and long term — can affect the heart. They look at broken heart syndrome (also known as takotsubo syndrome) and how stress can lead to an unhealthy lifestyle and, consequently, is a risk factor for cardiovascular disease.The editors also discuss how GPs and other primary care health professionals can support patients who are chronically stressed both by helping them to manage their stress levels and by addressing the risk factors that can develop as a consequence, directly or indirectly, of stress.You can access the website version of this podcast on MIMS Learning to make notes for your appraisal. MIMS Learning offers hundreds of hours of CPD for healthcare professionals, along with a handy CPD organiser.Please note: this podcast is presented by medical editors and discusses educational content written or presented by doctors, nurses and other healthcare professionals on the MIMS Learning website and at live events.Further learning on MIMS LearningAchieving new cholesterol targets in primary careCoronary artery disease in womenGuidance update: latest NICE guidelines on cardiovascular disease risk assessment and reductionGuidance update: latest NICE guidelines on type 2 diabetes in adultsGuidance update: NICE guidelines on hypertensionObesity in adultsPodcast: Professor Alex Miras on supporting people with obesityPodcast: NASP's Monica Boulton on making best use of social prescribing in primary careResources for supporting people to improve their mental wellbeingTakotsubo syndrome: clinical reviewWellbeing masterclass Hosted on Acast. See acast.com/privacy for more information.
Neuroprotection is just about pricey moonshot Alzheimer drugs; Green tea, melatonin, quercetin, aerobic exercise tackle brain inflammation; Glyphosate may contribute to Alzheimer's surge; Supplements to extend sleep; A popular social media influencer makes shady claims about blood pressure supplements; Diet can influence the prognosis of early ovarian cancer; Omega-3s slow biological aging; A natural antidote to hair graying.
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published updated meta-analysis on impact of gender-affirming hormonal therapy on cardiovascular risk factors in transgender health.
In this episode, Dr. Valentin Fuster discusses groundbreaking research on the interplay between cardiovascular risk factors and chronic kidney disease (CKD) progression among Chinese adults. Highlighting a study that reveals how effective management of hypertension, cholesterol, and blood glucose can significantly reduce the risks of cardiovascular events and mortality in CKD patients, the conversation emphasizes the crucial need for targeted treatment strategies to improve patient outcomes.
The debate between animal-based and plant-based meat alternatives (PBMAs) has garnered significant attention, especially concerning their impact on cardiovascular health. As PBMAs become increasingly popular, questions about their nutritional profiles and long-term health implications have emerged. Are these alternatives genuinely healthier than traditional meat, or do their highly processed nature and high sodium content undermine potential benefits? This discussion is crucial as dietary choices increasingly influence public health policies and consumer behaviors. Dr. Matthew Nagra's recent review in the Canadian Journal of Cardiology sheds light on these issues by analyzing the nutritional differences between PBMAs and meat. The review highlights the potential cardiovascular benefits of PBMAs, such as lower levels of saturated fat and cholesterol, alongside higher fiber content. However, the review also points out the significant variability in PBMAs' nutritional content, raising questions about standardization and consumer guidance. Understanding these differences is key to making informed dietary decisions and shaping future food industry practices. With growing consumer interest and public health implications, several pertinent questions arise: How do different PBMAs compare in their nutritional impact? What role does food processing play in their health outcomes? How can consumers make the best choices given the variability in PBMAs? In our discussion, Dr. Nagra will cover all these details, providing a comprehensive look at the current state of PBMAs and their role in a healthy diet. Timestamps: 01:59 Introducing Dr. Matthew Nagra 10:48 Nutritional Profiles of Plant-Based Meat Alternatives 14:39 Cardiovascular Risk Factors and Review Findings 21:17 Public Perception and Criticisms 25:10 Practical Advice for Choosing Plant-Based Meat Alternatives 34:29 Future Research Directions 43:51 Key Ideas Segment (Premium-only) Links: Subscribe to Sigma Nutrition Premium Go to episode page Receive our free weekly email: the Sigma Synopsis Enroll in the next cohort of our Applied Nutrition Literacy course
Wondering how to fine-tune your nutrition for peak endurance performance? I've got you covered. Today, I'll be sharing my top 10 "superfoods" that every endurance athlete should consider incorporating into their diet. I'm not talking about the typical marketing gimmick superfoods; I'm talking about nutrient-dense foods that genuinely enhance performance and overall health. Berries are rich in antioxidants, in particular flavonoids, that help combat inflammation and oxidative stress from workouts. They're also a great option for a low-carb, low-calorie snack that satisfies your sweet tooth. Berries are best when they're fresh, locally grown, and in season, but frozen berries can provide a good variety all year round! Eggs are an excellent source of high-quality protein and contain the amino acid leucine, which promotes muscle protein synthesis. They are also nutrient-dense, providing B vitamins, choline, selenium, vitamin A, iron, and phosphorus. Remember to eat the whole egg, not just the whites, as the yolks contain most of the nutrients. Quinoa is a protein-rich grain, packed with fibre and essential amino acids. It's a great choice plant-based source of protein for vegetarian or vegan athletes. It's also particularly beneficial for anyone balancing their carbohydrate and protein intake. Legumes are nutrient powerhouses rich in protein and fibre. They are great for gut health and help in muscle repair and recovery. They can be added to salads, casseroles, and even spaghetti but, add them to your diet slowly to avoid gastrointestinal discomfort. Nuts and Seeds offer a great mix of protein and healthy fats. Each type offers different benefits so try and include a variety in your diet. While they are calorie-dense, studies have shown we absorb fewer calories from nuts than previously believed, so don't hold back! Mushrooms are an excellent source of B vitamins, antioxidants, and essential minerals. They're also one of the few foods that can provide vitamin D, which they generate when exposed to UV light. Mushrooms offer so many benefits that I'm thinking of giving them their own episode in the future. In the meantime, make sure you add them to your diet wherever possible. Beetroots are known for their high nitrate content, which enhances blood flow and oxygen delivery to muscles. While you'd need to eat a lot to see significant performance benefits, adding beetroots into your diet will support your overall cardiovascular health. Extra Virgin Olive Oil is a great source of monosaturated fat, which we rarely get enough of. It also contains bioactive molecules that help reduce oxidative stress and inflammation. Recent studies even suggest that its anti-inflammatory properties can rival those of ibuprofen. Deep-Sea Fatty Fish, like salmon, tuna, and mackerel, are rich in omega-3 fatty acids, essential for cardiovascular health, joint health, and overall brain function. Most people eat fish occasionally, but not enough to receive the full benefits. Aim to include these in your diet two to three times a week. Green Leafy Vegetables are nutrient-dense, rich in vitamins A, C, K, E, and essential minerals. These versatile vegetables are great for protecting against disease and promoting overall health. So, don't just stick to spinach and kale; there are so many options here and eating a variety will bring maximum benefits! Remember, nutrition is about variety and balance. No single food item will make you a better athlete overnight, but incorporating a diverse range of these nutrient-dense foods into your diet will set you up for long-term health and optimal performance in your triathlon training. If you have any questions about incorporating these foods into your diet or want to discuss specific nutrition strategies, please feel free to reach out. REFERENCES: Richard C, Cristall L, Fleming E, Lewis ED, Ricupero M, Jacobs RL, Field CJ. Impact of Egg Consumption on Cardiovascular Risk Factors in Individuals with Type 2 Diabetes and at Risk for Developing Diabetes: A Systematic Review of Randomized Nutritional Intervention Studies. Can J Diabetes. 2017 Aug;41(4):453-463. doi: 10.1016/j.jcjd.2016.12.002. Epub 2017 Mar 27. PMID: 28359773. Hess J et al. Impact of Agaricus bisporus Mushroom Consumption on Gut Health Markers in Healthy Adults. Nutrients. 2018 Oct 2;10(10). pii: E1402. doi: 10.3390/nu10101402. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213353/ LINKS: Check how well you're doing when it comes to your nutrition with our 50 step checklist to Triathlon Nutrition Mastery: dietitianapproved.com/checklist Start working on your nutrition now with my Triathlon Nutrition Kickstart course: dietitianapproved.com/kickstart It's for you if you're a triathlete and you feel like you've got your training under control and you're ready to layer in your nutrition. It's your warmup on the path to becoming a SUPERCHARGED triathlete – woohoo! Join the waitlist for our next opening of the Triathlon Nutrition Academy www.dietitianapproved.com/academy Website: www.dietitianapproved.com Instagram: @Dietitian.Approved @triathlonnutritionacademy Facebook: www.facebook.com/DietitianApproved The Triathlon Nutrition Academy is a podcast by Dietitian Approved. All rights reserved. www.dietitianapproved.com/academySee omnystudio.com/listener for privacy information.
Commentary by Ashish Kumar
Join Dr. Sanjeev Goel and Dr. Anil Maheshwari in a deep dive into cardiovascular health, discussing key risk factors, advanced lipid tests, and the importance of individualized care. Learn about cholesterol markers, genetic influences, and lifestyle modifications that can lower cardiovascular risk. Gain insights into the complexity of heart health and the latest advancements in cardiovascular care. TIMESTAMPS: 00:00 - Intro 01:21 - Advocating for Your Health 03:45 - Ethnicity and Cardiovascular Risk 05:05 - Family History and Cardiovascular Risk 07:05 - LDL (Low-Density Lipoprotein) 10:32 - LDL Guidelines 12:51 - Oxidized LDL 14:03 - HDL (High-Density Lipoprotein) 16:33 - Total Cholesterol to HDL Ratio 19:54 - Triglycerides and Non-HDL Cholesterol 21:49 - Apolipoprotein B (APO B) and Lipoprotein A (Lp(a)) 24:21 - Lipoprotein A (continued), Genetic Risk, and Medication Considerations 30:13 - High Sensitivity CRP (hs-CRP) and Inflammation 33:15 - Additional Tests and Medication Options 36:02 - Conclusion Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs * Link to Study https://jamanetwork.com/journals/jama...
In this episode, I sit down with Dr. Jack Wolfson, a renowned cardiologist with a unique perspective on heart health that challenges conventional wisdom. Dr. Wolfson shares his insights on the true causes of cardiovascular disease, the overlooked importance of lifestyle factors, and why organ meats might be the missing piece in your diet for heart health. We also discuss the critical role of environmental factors, including mold exposure, and how they impact your cardiovascular system. Dr. Wolfson's approach offers practical, actionable advice grounded in nature, helping you make informed choices about your health and well-being. In this episode: 00:00 - Introduction 03:02 - The Critical Role of Lifestyle in Heart Health 04:44 - Top 3 Cardiovascular Risk Factors 05:18 - Nutrition and Diet: What Really Matters 08:01 - Advanced Markers for Assessing Heart Disease Risk 18:36 - Personal Blood Work Discussion and Insights 29:16 - The Importance of Organs in Your Diet 36:40 - Final Thoughts and Episode Wrap-Up Don't forget to subscribe for more insightful conversations with experts in health, fitness, and beyond. #PrimalShiftPodcast #JackWolfson #CardiovascularHealth Learn more: Shop my 100% grass-fed freeze-dried beef organ supplements. Learn the top health benefits of consuming organ meat (blog post). Make sure you tell your doctor to include these key metabolic health markers on your blood panel (YouTube video). Chronic inflammation (and thus, chronic disease) is largely driven by lifestyle factors, such as diet, environmental toxins, exercise and sleep. Check out my guide to living a healthy lifestyle for actionable tips you can implement today. Thank you to this episode's sponsor, OneSkin! OneSkin's lineup of topical skin health products leverage the power of the company's proprietary OS-01 peptide to remove dead skin cells, improve collagen production, increase skin hydration and more. Check out my before and after photos in my OneSkin review and visit OneSkin here. About Dr Jack Wolfson:Dr. Jack Wolfson is a board-certified cardiologist, a best-selling author, husband and father, as well as one of the nation's top natural heart doctors. Over the past two decades, more than 1 million people have enjoyed the warmth, compassion and transformational power of his natural heart health courses and events. Website: https://drjackwolfson.com Instagram: https://www.instagram.com/natural_heart_doctor/?hl=es Youtube: https://www.youtube.com/@NaturalHeartDoctor More From Michael Kummer: Website: https://michaelkummer.com YouTube: https://youtube.com/@MichaelKummer Instagram: https://instagram.com/mkummer82
The Real Truth About Health Free 17 Day Live Online Conference Podcast
In this segment, Dr. Heather Shenkman discusses the intricacies of the DASH diet and highlights various alternatives and supplements that can aid in reducing high blood pressure. She underscores the vital role of lifestyle changes in managing blood pressure alongside necessary medications. Shenkman also touches upon the impact of a plant-based diet in lowering cholesterol levels, emphasizing patient-centric strategies for better blood pressure control. #HeartHealth #LifestyleChanges #PlantBasedDiet
Guests Gwen Klinkner, DNP, RN, BC-ADM, CDCES, FADCES, and Melissa Magwire, RN, MSN, CDCES describe how to help patients with diabetes navigate behavior change principles to achieve glucose management including nutrition and exercise. They also examine pharmacotherapies for weight loss with glucose-lowering medications.CE Link: pcna.net/podcast/euglycemiaSURMOUNT Trials: https://www.nejm.org/doi/full/10.1056/NEJMoa2206038 ADCES: https://www.diabeteseducator.org/PNCA.net AHA.org Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes: doi: 10.1136/bmj.321.7258.405Comprehensive Management of Cardiovascular Risk Factors for Adults With Type 2 Diabetes: AHA Scientific Statement: doi:10.1161/CIR.0000000000001040Diabetes Self-management Education and Support in Adults With Type 2 Diabetes: A Consensus Report of the ADA, ADCES, AND, AAFP, AAPA, AANP, APhA: doi:10.1177/0145721720930959See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Commentary by Dr. Bonnie Ky
Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! Learn how to RAMP UP into longer fasting windows! Gain insights into the non-weight loss benefits of fasting! Personalize your own fasting schedule and consistent FAT LOSS results! Get answers to what breaks a fast, how to break a fast, and tips and tricks to accelerate your fasting wins! THE BLUEPRINT TO FASTING FOR FAT LOSS DOWNLOAD In today's episode, Dr. Scott and Tommy discuss why fasting is a sustainable and viable approach to improve your health dramatically, the optimal time for physical activity around food intake, physical activities and exercise in relationship to diabetes, fasting and exercise recommendation and so much more. Show Transcript: www.thefastingforlife.com/blog Nutrisense CGM LINK to Discount [target url = https://bit.ly/44H6IQc] - Get $30 off and one-month free dietician support with the PROMO CODE “FASTINGFORLIFE” www.nutrisense.io/fastingforlife [target url = https://bit.ly/44H6IQc] Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! Fasting For Life Community - Join HERE New to the podcast and wondering where to start? Head to the website and download our Fast Start Guide, 6 simple steps to put One Meal a Day Fasting (OMAD) into practice! Get our NEW sleep guide here! SLEEP GUIDE DIRECT DOWNLOAD If you enjoy the podcast, would you please tap on the stars below and consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them Article Links https://pubmed.ncbi.nlm.nih.gov/27926890/ https://pubmed.ncbi.nlm.nih.gov/22780564/ https://pubmed.ncbi.nlm.nih.gov/15505129/ https://www.medicalnewstoday.com/articles/317536#blood-sugar-charts
Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Steve Grinspoon, MD Many studies over the last few years have shown that the risks of cardiovascular disease have increased between 50 to 100 percent among patients with HIV. So what steps need to be taken to help reduce this risk for our patients? Here to discuss what we need to know is Dr. Mary Katherine Cheeley and Dr. Steven Grinspoon, Professor of Medicine at Harvard Medical School and Chief of the Metabolism Unit at Massachusetts General Hospital.
Heart attacks and dementia are linked, a new Johns Hopkins study shows. Michelle Johannsen, a stroke and cardiovascular expert and study author, says reducing your risk factors even before the first problem starts is the best strategy. Johannsen: If you're … Starting to control cardiovascular risk factors early is your best course, Elizabeth Tracey reports Read More »
We've probably all been reprimanded for eating too fast at the dinner table or suffered the dreaded “itis” from eating way too much food at a family gathering. Our society and the systems we've developed to feed it have ballooned to such a point that they easily override our natural bodily systems that tell us when we've had enough to eat. When nearly 50% of the United States population is projected to have obesity by 2030, can something as simple as changing the speed with which we eat really be an effective tool for weight loss and sustaining a healthy body?In today's short episode of ZOE Science & Nutrition, Jonathan and Sarah ask: What is eating rate and does it have any impact on our health?Studies referenced in the episode:Does Eating Fast Make You Gain More Weight?Eating slowly increases the postprandial response of the anorexigenic gut hormones, peptide YY and glucagon-like peptide-1 Association between eating rate and obesity: a systematic review and meta-analysis Eating too fast may lead to weight gain, heart disease Is eating too quickly bad for your health? How Important Is Eating Rate in the Physiological Response to Food Intake, Control of Body Weight, and Glycemia? A systematic review and meta-analysis examining the effect of eating rate on energy intake and hunger Effects of eating rate and eating topography on meal size and satiety The effect of eating rate on satiety in healthy and overweight people – A pilot study Association between Self-Reported Eating Rate, Energy Intake, and Cardiovascular Risk Factors in a Multi-Ethnic Asian Population Association between Self-Reported Eating Rate, Energy Intake, and Cardiovascular Risk Factors in a Multi-Ethnic Asian PopulationControl of overweight and obesity in childhood through education in meal time habits. The ‘good manners for a healthy future' programme*Eating slowly led to decreases in energy intake within meals in healthy...
Commentary by Dr. Valentin Fuster
This episode, we're sitting down with Dr. Sandhya Bassin to discuss the connection between plant-based nutrition and endocrine health. Sources: A plant-based diet for the prevention and treatment of type 2 diabetes McMacken M, Shah S. A plant-based diet for the prevention and treatment of type 2 diabetes. J Geriatr Cardiol. 2017 May;14(5):342-354. doi: 10.11909/j.issn.1671-5411.2017.05.009. PMID: 28630614; PMCID: PMC5466941. Effect of High Protein vs High Carbohydrate Intake on Insulin Sensitivity, Body Weight, Hemoglobin A1c, and Blood Pressure in Patients with Type 2 Diabetes Mellitus Sargrad KR, Homko C, Mozzoli M, Boden G. Effect of high protein vs high carbohydrate intake on insulin sensitivity, body weight, hemoglobin A1c, and blood pressure in patients with type 2 diabetes mellitus. J Am Diet Assoc. 2005 Apr;105(4):573-80. doi: 10.1016/j.jada.2005.01.009. PMID: 15800559. A Low-Fat Vegan Diet Improves Glycemic Control and Cardiovascular Risk Factors in a Randomized Clinical Trial in Individuals With Type 2 Diabetes Barnard ND, Cohen J, Jenkins DJ, Turner-McGrievy G, Gloede L, Jaster B, Seidl K, Green AA, Talpers S. A low-fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes. Diabetes Care. 2006 Aug;29(8):1777-83. doi: 10.2337/dc06-0606. PMID: 16873779.
Interview with Xin You Tai, MD, author of Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors. Hosted by Cynthia E. Armand, MD. Related Content: Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors
Interview with Xin You Tai, MD, author of Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors. Hosted by Cynthia E. Armand, MD. Related Content: Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors
Today we are continuing our cholesterol series. In Part One we discussed what cholesterol actually is, as it is often vilified in conventional medicine. We learned that our body needs cholesterol in order to build healthy cells. Cholesterol is a part of the outer layer of our cells, the membrane of the cells. It is also the initial part of the steroidogenic pathway. In Part Two we dove deep into LDL and HDL. We discussed that cholesterol cannot travel throughout the body on its own – it needs a friend. LDL is responsible for moving cholesterol throughout the body to the tissues, whereas HDL's role is to bring cholesterol from the tissues back to the liver. Today we are going to discuss apolipoproteins, in particular, Apo B and Apo A. We are going to talk about what they are – the role they play in the body – the cardiovascular risks or benefits associated with higher levels. Just a quick disclaimer that this podcast is meant for educational purposes only and is not meant to diagnose or be a substitute for medical advice from your practitioner. ** Follow me on Instagram: https://www.instagram.com/thefunctionalnursepractitioner/ ** Level up your products: https://www.ewg.org/ewgverified/ ** Find a certified Functional Medicine Practitioner: https://www.ifm.org/find-a-practitioner/ ** Interesting articles for more information** ApoPred: Identification of Apolipoproteins and Their Subfamilies With Multifarious Features: https://www.frontiersin.org/articles/10.3389/fcell.2020.621144/full Effect of APOB polymorphism rs562338 (G/A) on serum proteome of coronary artery disease patients: a “proteogenomic” approach: https://www.nature.com/articles/s41598-021-02211-4 Biochemistry, Apolipoprotein B: https://www.ncbi.nlm.nih.gov/books/NBK538139/ Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540246/ Physiological Bases for the Superiority of Apolipoprotein B Over Low-Density Lipoprotein Cholesterol and Non–HighDensity Lipoprotein Cholesterol as a Marker of Cardiovascular Risk: https://www.ahajournals.org/doi/10.1161/JAHA.122.025858 The Association between Apolipoprotein B, Cardiovascular Risk Factors and Subclinical Atherosclerosis—Findings from the SEPHAR National Registry on Hypertension in Romania: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917572/ Pleiotropic Effects of APOB Variants on Lipid Profiles, Metabolic Syndrome, and the Risk of Diabetes Mellitus: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735756/ Apolipoprotein B Displays Superior Predictive Value Than Other Lipids for Long-Term Prognosis in Coronary Atherosclerosis Patients and Particular Subpopulations: A Retrospective Study: https://pubmed.ncbi.nlm.nih.gov/35902283/ ApoB and Non-HDL Cholesterol Versus LDL Cholesterol for Ischemic Stroke Risk: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545003/ Glycation Reduces the Stability of ApoAI and Increases HDL Dysfunction in Diet-Controlled Type 2 Diabetes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800833/ HDL Particle Subspecies and Their Association With Incident Type 2 Diabetes: The PREVEND Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118359/ Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target: https://www.mdpi.com/2218-1989/11/10/690 A Role for Proteoglycans in Vascular Disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110991/ Association of apolipoprotein A1 with osteoporosis: a cross-sectional study: https://pubmed.ncbi.nlm.nih.gov/36864426/ Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926306/ ApoA1 and ApoA1-specific self-antibodies in cardiovascular disease: https://www.nature.com/articles/labinvest201656
While the US Department of Health and Human Services recommends a sodium intake of less than 2,300 mg/day, about 9 of 10 American adults exceed that limit. Increased sodium intake is believed to have a direct effect on a variety of negative cardiovascular outcomes such as coronary heart disease, left ventricular hypertrophy, and stroke. Recognizing the impact of dietary sodium on diseases like hypertension and CVD, the FDA recently released voluntary guidance for industry on the target mean and upper concentrations for sodium in commercially processed, packaged, and prepared foods. The guidance was intended to provide a measurable voluntary goal to help Americans to reduce their average sodium intake by 12% over the next 2.5 years, and plans for further iterative reductions in the future. In addition to daily dietary (food and drink) sodium, both prescription and over-the-counter medications can contribute to increasing patients' total sodium intake per day. Additionally, other risk factors—such as smoking the absence of physical activity, and poor sleep hygiene—that contribute to developing cardiovascular conditions can be modified by maintaining a healthy and balanced lifestyle. This episode is produced by Sleep Review. It is episode 5 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and NarcolepsyLink.com for more information. In episode 5, listen as Sleep Review's Sree Roy and cardiologist-sleep specialist Barbara Hutchinson, MD, PhD, FACC, discuss:The FDA recently released guidance on voluntary target concentrations for sodium, in commercially processed packaged and prepared foods. What are your thoughts on this reduced goal for sodium intake, in terms of impact on cardiovascular risk?What are some links between high sodium intake and adverse cardiovascular outcomes?What should people be aware of with regard to medication use and sodium intake?How should cardiovascular risk be discussed when determining the management plan for sleep disorders?Can you share an example of modifying a sleep disorder patient's management plan, due to an emerging cardiovascular risk or disease?Beyond sodium intake, what are some of the other modifiable cardiovascular risk factors that everyone, regardless of whether they have a sleep disorder or not, should be aware of?
While the US Department of Health and Human Services recommends a sodium intake of less than 2,300 mg/day, about 9 of 10 American adults exceed that limit. Increased sodium intake is believed to have a direct effect on a variety of negative cardiovascular outcomes such as coronary heart disease, left ventricular hypertrophy, and stroke. Recognizing the impact of dietary sodium on diseases like hypertension and CVD, the FDA recently released voluntary guidance for industry on the target mean and upper concentrations for sodium in commercially processed, packaged, and prepared foods. The guidance was intended to provide a measurable voluntary goal to help Americans to reduce their average sodium intake by 12% over the next 2.5 years, and plans for further iterative reductions in the future. In addition to daily dietary (food and drink) sodium, both prescription and over-the-counter medications can contribute to increasing patients' total sodium intake per day. Additionally, other risk factors—such as smoking the absence of physical activity, and poor sleep hygiene—that contribute to developing cardiovascular conditions can be modified by maintaining a healthy and balanced lifestyle. This episode is produced by Sleep Review. It is episode 5 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and NarcolepsyLink.com for more information. In episode 5, listen as Sleep Review's Sree Roy and cardiologist-sleep specialist Barbara Hutchinson, MD, PhD, FACC, discuss:The FDA recently released guidance on voluntary target concentrations for sodium, in commercially processed packaged and prepared foods. What are your thoughts on this reduced goal for sodium intake, in terms of impact on cardiovascular risk?What are some links between high sodium intake and adverse cardiovascular outcomes?What should people be aware of with regard to medication use and sodium intake?How should cardiovascular risk be discussed when determining the management plan for sleep disorders?Can you share an example of modifying a sleep disorder patient's management plan, due to an emerging cardiovascular risk or disease?Beyond sodium intake, what are some of the other modifiable cardiovascular risk factors that everyone, regardless of whether they have a sleep disorder or not, should be aware of?
Commentary by Dr. Shalini Moningi
Elyn is back to discuss the latest research on vascular contributions to Alzheimer disease! Tune in to hear about proteomic changes with amyloid deposition in the vasculature, new therapeutic avenues, and a more detailed account of the perivascular space. If you're interested in factors beyond amyloid and tau in the Alzheimer disease pathology, this is a great place to start! Sections in this episode: Cardiovascular Risk Factors (3:45) White Matter Hyperintensities (8:51) Cerebral Amyloid Angiopathy and the Blood-Brain Barrier (15:47) Therapeutic Avenues (24:00) -------------------------------------------------------------- To find the numbered bibliography with all the papers covered in this episode, click here, or use the link below:https://drive.google.com/file/d/1Gswzf5F_ptPPY2OVH3Qdk15aZpNMyaIo/view?usp=sharingTo access the folder with ALL our bibliographies, follow this link (it will be updated as we publish episodes and process bibliographies), or use the link below:https://drive.google.com/drive/folders/1bzSzkY9ZHzzY8Xhzt0HZfZhRG1Gq_Si-?usp=sharingYou can also find all of our bibliographies on our website: www.amindr.com. --------------------------------------------------------------Follow-up on social media for more updates!Twitter: @AMiNDR_podcastInstagram: @AMiNDR.podcastFacebook: AMiNDR Youtube: AMiNDR PodcastLinkedIn: AMiNDR Podcast Email: amindrpodcast@gmail.com -------------------------------------------------------------- Please help us spread the word about AMiNDR to your friends, colleagues, and networks! And if you could leave us a rating and/or review on your streaming app of choice (Apple Podcasts, Spotify, or wherever you listen to the podcast), that would be greatly appreciated! It helps us a lot and we thank you in advance for leaving a review! Don't forget to subscribe to hear about new episodes as they come out too. Thank you to our sponsor, the Canadian Consortium of Neurodegeneration in Aging, or CCNA, for their financial support of this podcast. This helps us to stay on the air and bring you high quality episodes. You can find out more about the CCNA on their website: https://ccna-ccnv.ca/. Our team of volunteers works tirelessly each month to bring you every episode of AMiNDR. This episode was scripted and hosted by Elyn Rowe, edited by Chihiro Abe, and reviewed by Cassi Friday and Judy Cheng. The bibliography was created by Lara Onbasi and the wordcloud was created by Sarah Louadi (www.wordart.com). Big thanks to the sorting team for taking on the enormous task of sorting all of the Alzheimer's Disease papers into episodes each month. For July 2022, the sorters were Sarah Louadi, Eden Dubchak, Ben Cornish, Ellen Koch, Dana Clausen, Christy Yu, and Elyn Rowe. Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Lara Onbasi for keeping everything running smoothly.Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic. https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w -------------------------------------------------------------- If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways. --------------------------------------------------------------*About AMiNDR: * Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"
Ever thought there was more to Alzheimer disease than the plaques and tangles? You've come to the right place. Join Elyn for a guide through the latest research on vascular contributions to Alzheimer disease. June 2022 brought lots of new insight into how vascular hallmarks interact with the classic AD hallmarks to influence cognition, emphasis on vascular pathology in familial Alzheimer disease, and so much more. Tune in for a riveting episode! Sections in this episode: Cardiovascular Risk Factors (4:06) Interactions of Vascular Pathology with AD Hallmarks (6:58) Vascular Abnormalities in Familial AD (12:28) APOE, Retinal Imaging, and Proteomics (18:12) Treatments Targeting the Vasculature (23:22) -------------------------------------------------------------- To find the numbered bibliography with all the papers covered in this episode, click here, or use the link below:https://drive.google.com/file/d/1S5T16qg9x-ERr9_UlcOq0BZCsTYmG6Vr/view?usp=sharingTo access the folder with ALL our bibliographies, follow this link (it will be updated as we publish episodes and process bibliographies), or use the link below:https://drive.google.com/drive/folders/1bzSzkY9ZHzzY8Xhzt0HZfZhRG1Gq_Si-?usp=sharingYou can also find all of our bibliographies on our website: www.amindr.com. --------------------------------------------------------------Follow-up on social media for more updates!Twitter: @AMiNDR_podcastInstagram: @AMiNDR.podcastFacebook: AMiNDR Youtube: AMiNDR PodcastLinkedIn: AMiNDR PodcastEmail: amindrpodcast@gmail.com -------------------------------------------------------------- Please help us spread the word about AMiNDR to your friends, colleagues, and networks! And if you could leave us a rating and/or review on your streaming app of choice (Apple Podcasts, Spotify, or wherever you listen to the podcast), that would be greatly appreciated! It helps us a lot and we thank you in advance for leaving a review! Don't forget to subscribe to hear about new episodes as they come out too. Thank you to our sponsor, the Canadian Consortium of Neurodegeneration in Aging, or CCNA, for their financial support of this podcast. This helps us to stay on the air and bring you high quality episodes. You can find out more about the CCNA on their website: https://ccna-ccnv.ca/. Our team of volunteers works tirelessly each month to bring you every episode of AMiNDR. This episode was scripted and hosted by Elyn Rowe, edited by Chihiro Abe, and reviewed by Cassi Friday and Judy Cheng. The bibliography and wordcloud were both created by Sarah Louadi (www.wordart.com). Big thanks to the sorting team for taking on the enormous task of sorting all of the Alzheimer's Disease papers into episodes each month. For June 2022, the sorters were Sarah Louadi, Eden Dubchak, Ben Cornish, Naila Kuhlmann, and Elyn Rowe. Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Lara Onbasi for keeping everything running smoothly.Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic. https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w -------------------------------------------------------------- If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways. --------------------------------------------------------------*About AMiNDR: * Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"
Matt, Jess, and guest host Marcia Pescador Jimenez discuss the impact of cardiovascular risk factors in childhood and their relation to cardiovascular events as adults, they review the benefits of […]
Commentary by Dr. Valentin Fuster
Commentary by Dr. Annabelle Voglman
How can we better manage cardiovascular risk in patients with type 2 diabetes? Find out about this and more in today's PV Roundup podcast.
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Cardiovascular Risk Factors, Ethnic Disparities, Covid-19, Mortality And Nutrition - Kim Williams, M.D. - Offstage Interview 2021 Kim Williams, M.D. • https://doctors.rush.edu/details/1728/kim-williams-sr-cardiovascular_disease-chicago-oak_park • Past President of the American College of Cardiology Kim Allan Williams Sr. (born 1955) is an American cardiologist. He is a Fellow of the American College of Cardiology and served as its president from 2015 to 2016. He is currently a trustee of the organization. He has board certifications in internal medicine, cardiovascular diseases, nuclear medicine, nuclear cardiology, and cardiovascular computed tomography. He has served on the faculty of the Pritzker School of Medicine, the Wayne State University School of Medicine in Detroit, Michigan, and since 2013 at Rush University Medical Center in Chicago, where he is the head of the cardiology department Williams has served as president of the American Society of Nuclear Cardiology, chairman of the Coalition of Cardiovascular Organizations, and chairman of the board of the Association of Black Cardiologists, among other positions. Passionate believers in whole food plant based diets, no chemicals, minimal pharmaceutical drugs, no GMO's. Fighting to stop climate change and extinction. Connect with The Real Truth About Health: Sign Up for our Membership Club and Get 30 Days Free
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Cardiovascular Risk Factors, Ethnic Disparities, Covid-19, Mortality And Nutrition - Kim Williams, M.D. Kim Williams, M.D. • https://doctors.rush.edu/details/1728/kim-williams-sr-cardiovascular_disease-chicago-oak_park • Past President of the American College of Cardiology Kim Allan Williams Sr. (born 1955) is an American cardiologist. He is a Fellow of the American College of Cardiology and served as its president from 2015 to 2016. He is currently a trustee of the organization. He has board certifications in internal medicine, cardiovascular diseases, nuclear medicine, nuclear cardiology, and cardiovascular computed tomography. He has served on the faculty of the Pritzker School of Medicine, the Wayne State University School of Medicine in Detroit, Michigan, and since 2013 at Rush University Medical Center in Chicago, where he is the head of the cardiology department Williams has served as president of the American Society of Nuclear Cardiology, chairman of the Coalition of Cardiovascular Organizations, and chairman of the board of the Association of Black Cardiologists, among other positions. Passionate believers in whole food plant based diets, no chemicals, minimal pharmaceutical drugs, no GMO's. Fighting to stop climate change and extinction. Connect with The Real Truth About Health: Sign Up for our Membership Club and Get 30 Days Free
Overview: Listen as Dr. Eden Miller and Dr. James O'Keefe discuss how diabetes can affect cardiovascular health. These key experts will also review key cardiovascular outcomes trials and their impact on treatment guidance for patients with type 2 diabetes. Guest: Eden M. Miller, DO & James H. O'Keefe, MD
Pregnancy-Related and Other Women Specific Cardiovascular Risk Factors Guest: Rekha Mankad, M.D. (@RMankadMD) Host: Stephen L. Kopecky, M.D. (@DrSteveKopecky) Data supports that women's risk of heart disease has been underrecognized — women are dying of heart disease at increasingly higher rates. Women have the same regular risk factors as men, including high blood pressure, high cholesterol, diabetes and smoking, but there are some additional female-specific risk factors. Joining us today to discuss pregnancy and cardiovascular risk is Rekha Mankad, M.D., a noninvasive cardiologist at Mayo Clinic in Rochester, Minnesota, with special interest in heart disease in women. Specific topics discussed: Guidelines that address women's risk factors for heart disease Complications related to menopause and pregnancy Impact of diabetes on heart disease in women Preventive screening and risk assessment Autoimmune diseases and heart disease in women Impact of marriage on women's risk of heart disease Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV. No CME credit offered for this episode. Podcast transcript can be found here.
Overview: Listen as Dr. Eden Miller and Dr. James O'Keefe discuss how diabetes can affect cardiovascular health. These key experts will also review key cardiovascular outcomes trials and their impact on treatment guidance for patients with type 2 diabetes. Guest: Eden M. Miller, DO & James H. O'Keefe, MD
Host: Eden Miller, DO Host: James O'Keefe, MD Drs. Eden Miller and James O'Keefe discuss how cardiovascular risk factors can impact patients with type 2 diabetes and provide an overview of resources to help HCPs manage the disease. This is part 2 of a 3-part podcast series. Please listen to podcast 1 before listening to this podcast. Copyright © 2021 Boehringer Ingelheim Pharmaceuticals, Inc. All rights reserved.SC-US-69642-D (06/2021)
In our first podcast I asked Joel to provide any interventional studies showing harm from red meat, or any unprocessed meat. He was unable to provide these studies at that time, or in the 2 weeks that followed before I released our podcast debate. After that time he wrote a blog post with his thoughts in response to many of the points I raised during the podcast, providing what he believed to be studies corroborating his points. This podcast is a solo-cast in which I respond to his blog post points to show some counter points and point out that I still do not believe his case for plant-based diets is able to be substantiated. I’ve reached out to Joel to see if he will come back on the podcast for a part two, but he has not yet responded. Will keep you posted! #theremembering Time stamps: 0:10:07 Did Dr. Joel Furhman ever send me those studies that demonstrated red meat has a damaging affect on humans? 0:12:42 Reviewing Dr. Joel Fuhrman's blog post regarding plant foods vs animal foods 0:18:27 Association of animal and plant protein intake with all-cause and cause-specific mortality 0:23:17 Meat intake and cause-specific mortality: a pooled analysis of asian prospective cohort studies 0:24:27 Mortality in british vegetarians 0:28:07 Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers 0:29:25 Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humans 0:29:47 Isocaloric diets high in animal or plant protein reduce liver fat and inflammation in individuals with type 2 diabetes 0:30:08 Effects of plant and animal high protein diets on immune-inflammatory biomarkers: a 6-week intervention trial 0:30:37 Changes in Dietary Fat Intake Alter Plasma Levels of Oxidized Low-Density Lipoprotein and Lipoprotein(a) 0:34:47 Cancer incidence in vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford) 0:37:14 Mortality in vegetarians and comparable nonvegetarians in the United Kingdom 0:38:47 Beef tallow increases apoptosis and decreases aberrant crypt foci formation relative to soybean oil in rat colon 0:41:12 Potential effects of reduced red meat compared with increased fiber intake on glucose metabolism and liver fat content: a randomized and controlled dietary intervention study 0:44:27 Validity of U.S. nutritional surveillance:National Health and Nutrition Examination Survey caloric energy intake data, 1971-2010 0:47:47 Effect of Legumes as Part of a Low Glycemic Index Diet on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes Mellitus - A Randomized Controlled Trial 0:50:37 Bean Consumption Is Associated with Greater Nutrient Intake, Reduced Systolic Blood Pressure, Lower Body Weight, and a Smaller Waist Circumference in Adults: Results from the National Health and Nutrition Examination Survey 1999-2002 0:57:52 The actions of exogenous leucine on mTOR signalling and amino acid transporters in human myotubes 1:01:37 Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population 1:05:27 Nutrition for the Japanese elderly 1:07:07 The capacity of foodstuffs to induce innate immune activation of human monocytes in vitro is dependent on food content of stimulants of Toll-like receptors 2 and 4 1:12:52 Fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis but impairs LPS dephosphorylation activity causing sepsis 1:16:07 Red meat and colon cancer: A review of mechanistic evidence for heme in the context of risk assessment methodology 1:19:32 Red meat enhances the colonic formation of the DNA adduct O6-carboxymethyl guanine: implications for colorectal cancer risk 1:24:07 Assessment of Causal Direction Between Gut Microbiota-Dependent Metabolites and Cardiometabolic Health: A Bidirectional Mendelian Randomization Analysis 1:25:27 Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels 1:26:22 Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease 1:35:37 Obesity is associated with hypothalamic injury in rodents and humans 1:36:07 Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice 1:36:37 Animal source foods: Sustainability problem or malnutrition and sustainability solution? Perspective matters Sponsors: Heart & Soil: www.heartandsoil.co White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order Belcampo: www.belcampo.com use code: CarnivoreMD for 20% off your order BluBlox: Blublox.com, use CarnivoreMD for 15% your order The Cold Plunge: TheColdPlunge.com, use code CarnivoreMD for $111 off your cold plunge
In this podcast, Susan Hutchinson, MD, discusses the implications for her team's research presented in the session "Oral Rimegepant 75 mg is Safe and Well Tolerated in Adults With Migraine and Cardiovascular Risk Factors: Results of a Multicenter, Long-Term, Open-Label Safety Study" at the American Academy of Neurology's 2021 Virtual Annual Meeting.
Dr. Susan Hutchinson discusses her abstract, "Oral Rimegepant 75 mg is Safe and Well Tolerated in Adults With Migraine and Cardiovascular Risk Factors: Results of a Multicenter, Long-Term, Open-Label Safety Study". You can view her abstract and others here: https://index.mirasmart.com/AAN2021/
Commentary by Dr. Elizabeth Hibler
Interview with Christoph U. Correll, MD, author of Association Between Cardiovascular Risk Factors and Cognitive Impairment in People With Schizophrenia: A Systematic Review and Meta-analysis
Interview with Christoph U. Correll, MD, author of Association Between Cardiovascular Risk Factors and Cognitive Impairment in People With Schizophrenia: A Systematic Review and Meta-analysis
In this episode Dr. Austin Robinson is leading our discussion of a paper entitled, “Bariatric Surgery-Induced Changes in Intima-Media Thickness and Cardiovascular Risk Factors in Class 3 Obesity: A 3-Year Follow-Up Study”. This paper was published in the journal of Obesity this August and continues our discussion of the many beneficial effects of bariatric surgery. Along with this episode we will also be posting a discussion with one of our colleagues at UIC Dr. Rich Severn. Rich is a DPT and PhD candidate at UIC whom we all worked with when we were at UIC. Be sure to catch our discussion with him on the awesome work he and his mentor Shane Phillips have done in collaboration with a bariatric surgery group at UIC examining the microvascular benefits of bariatric surgery. Main article DOI: 10.1002/oby.22905 DOIs for other relevant references: Arteriole Function in Obese Visceral Adipose (Boston Med) - DOI: 10.1161/ATVBAHA.111.235846 Arteriole Function in Obese Visceral Adipose (Shane Philips UIC) - DOI: 10.1111/micc.12164 NO Dependent Dilation and FMD -DOI: 10.1038/ajh.2012.8 Time Stamps Episode Introduction 00:00:00 – 00:02:00 Catching Up 00:02:00 – 00:13:24 Austin's Previous Work with Microvessels from Adipose Biopsies 00:13:24 – 00:26:19 Potential Consequences of Poor Adipose Vascular Function 00:26:19 – 00:31:42 Manuscript Introduction and Methods 00:31:42 – 00:42:17 Framingham Score and Study 00:42:17 – 00:45:13 Study Design 00:45:13 – 00:54:04 Results (Table 1) 00:54:04 – 00:58:29 Results (Table 2) 00:58:29 – 01:04:24 Results (Figure 1) 01:04:24 – 01:11:18 Results (Figure 2) 01:11:18 – 01:13:33 Results (Table 3) 01:13:33 – 01:14:33 Discussion/Main Take Away 01:14:33 – 01:24:51 Closing Remarks 01:24:51 – End
Interview with Martha Y. Kubik, PhD, RN, USPSTF member and coauthor of Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors
Hey friends, today it's all about nuts, and I don't mean going nuts from the kids or work; no, we're talking about the ones you nibble on when you need a snack or the ones you eat while at a holiday party. Some people aren't sure if eating nuts is healthy for them or not. As they are high in fat, most people associate that with not being a good thing. However, fats are not the enemy when we are talking about healthy fats, which nuts have. Sure, if you eat a whole bag full, that isn't ideal, but if we are talking about normal servings, which we will get into, there is nothing wrong with eating nuts. In fact, they are known to improve your health, not deplete it. Yes, you heard me right, nuts are tremendous! Now, let's get into why that is. It's not a good idea to avoid nuts Melissa Diane Smith, a holistic nutritionist, who looked closely at the 2017 Global Burden of Disease Study, summarized this, "nearly 500 researchers examined nearly 100,00 data sources" concerning the most comprehensive analysis of the cause of death. What they found was quite shocking. One of the leading causes, or 'dietary risk factors for death' was not eating enough nuts. "Eating more vegetables could potentially save 1.8 million lives, but eating more nuts and seeds might save 2.5 million." According to the study, one of the main 'healthy foods missing from most diets around the world actually are nuts and seeds!" What makes nuts so healthy? Remember when we were talking about healthy fats? Well, that is one reason nuts are so good for you. Others include but are not limited to: dietary fibervegetable proteinvitamins such as E, folic acid (a B vitamin), niacin, potassium.different minerals to include zinc, copper, and magnesium. In addition, they contain amino acid arginine, which helps your body build protein along with high antioxidant properties keeping your body's overall health. Keeping a strong heart Multiple studies show that eating "five or more servings (five ounces) of nuts per week" reduced "coronary heart disease incidence and death." Healthy blood sugar levels An article was written by Nutrients in November of 2017 that talks about "Benefits of Nut Consumption on Insulin Resistance and Cardiovascular Risk Factors." To summarize the findings they found, "nut consumption could play a role in reducing the risk of Type 2 Diabetes (T2DM) and cardiovascular disease (CVD) through improvement in glucose and lipid metabolism, weight maintenance and improved endothelial function" (a thin membrane that lines the inside of the heart and blood vessels.) As nuts are low in carbohydrates, they rarely raise a person's blood sugar levels. See the chart below for dietary information. Nutrient content of raw nuts per 100 g *. AlmondWalnutHazelnutMacadamiaPecanPistachioBrazil NutCashew NutPeanutPine NutChest NutEnergy (kcal)579654628718691560659553567673213Carbohydrate (g)21.5513.7116.713.8213.8627.1711.7430.191613.0845.54Protein (g)21.1515.2314.957.919.1720.1614.3218.222613.692.42Lysine (g)0.5680.4240.420.0180.2871.1380.490.9280.9260.540.143Arginine (g)2.4652.2782.2111.4021.1772.1342.142.1233.0852.4130.173Total fat (g)49.9365.2160.7575.7771.9745.3267.143.854968.372.26Saturated fat (g)3.86.1264.46412.0616.185.90716.1347.78374.890.425MUFA (g)31.558.93345.65258.87740.80123.25723.87923.7972418.760.78PUFA (g)12.32947.1747.921.50221.61414.3824.3997.8451634.070.894Total Fiber (g)12.56.79.78.69.610.67.538.53.78.1Folate (μg)449811311225122252403462Calcium (mg)26998114857010516037921627Magnesium (mg)27015816313012112137629216825132Sodium (mg)1205013121823Potassium (mg)7334416803684101025659660705597518Copper (mg)1.031158617250.7561.21.31.74321951.1441.3240.447Iron (mg)3.712.914.73.692.533.922.436.684.585.531.01Zinc (mg)3.123.092.451.34.532.24.065.783.276.450.52Selenium (μg)4.14.92.43.63.87191719.97.20.7NAα-tocopherol (mg)25.630.715.030.541.42.865.6508.339.33NAβ- 0.230.150.3300.3900.010.03NA0NAγ- 0.0720.830024.
5 October 2020 COVID Update – Trump & Cardiovascular Risk Factors 主題: 有關特朗普感染新冠肺炎; 並心血管危險因素 City of Parramatta Libraries Health Awareness Talks in Cantonese Language. In partnership with Australian Chinese Medical Association. Health talks to promote better understanding and awareness of common health issues and related services in the Chinese Australian community. Presented by Professor Stephen Li. Chemical Pathologist | Clinical Lipidologist | Chartered Manager Director Core Pathology & Clinical Chemistry, Pathology West, NSW Health Pathology Director Westmead Hospital Lipid Clinic Chair, Community Health, ACMA Honorary President and Foundation Fellow, ACMA
The UK has officially entered an economic recession but what does that mean for your health? On this episode of the Fresh Heart Podcast we explore the health effects of financial downturns and how you can protect your heart in difficult economic times. Research looking at health in times of economic hardship is counterintuitive. Did you know there is data suggesting that when high income countries enter a recession, the mortality rate falls? Despite this surprising finding, recessions are stressful and they affect us all in different ways. Listen in and find out how to optimise your cardiac health during this difficult time. If you have been affected by the issues discussed in this podcast, you can find support in the links below. Financial support for Individuals: https://www.vulnerabilityregistrationservice.co.uk/get-financial-help-from-organisation-and-charities/ https://www.turn2us.org.uk/get-support https://www.stepchange.org/debt-info/emergency-funding.aspx You can find a list of helpful organisations that support mental health at: https://www.nhs.uk/conditions/stress-anxiety-depression/mental-health-helplines/ For more information about the Fresh Heart Project visit our website http://www.freshheartproject.com. If you have any suggestions or if you would like to share your own personal story please do get in touch @freshheartproject on Instagram, @freshheartproj on Twitter or via the website. Remember, be kind to yourself and small, sustainable steps lead to great change. Podcast References [1] Ruhm CJ. Are recessions good for your health? Q J Econ 2000; 115: 617-50 [2] Ruhm CJ. Good times make you sick. J Health Econ 2003; 22: 637-58 [3] Gerdtham UG, Ruhm CJ. Deaths rise in good economic times: evidence from the OECD. Econ Hum Biol 2006; 4: 298-316 [4] Ruhm CJ. A healthy economy can break your heart. Demography 2008; 44: 829-48 [5 ] Granados JAT et al. Cardiovascular Risk Factors, Depression, and Alcohol Consumption During Joblessness and During Recessions Among Young Adults in CARDIA. Am J Epidemiol 2018 Nov 1;187(11):2339-2345. [6] Astell-Burt T, Feng X. Health and the 2008 Economic Recession: Evidence from the United Kingdom (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577686/) . PLoS One. 2013; 8(2): e56674. Published online 2013 Feb 20.
Commentary by Dr. Valentin Fuster
Editor in Chief Fred Rivara and Deputy Editor Steve Fihn discuss research published in JAMA Network Open in August 2020
SHR # 2569 :: CBD May Help Avert Lung Destruction in COVID-19 plus BS Science Alert: Plant-based Meats Improve Some Cardiovascular Risk Factors - Dr. Babak Baban and Dr. Jack Yu - Cannabidiol, or CBD, may help reduce the cytokine storm and excessive lung inflammation that is killing many patients with COVID-19, researchers say. While more work, including clinical trials to determine optimal dosage and timing, is needed before CBD becomes part of the treatment for COVID-19, researchers at the Dental College of Georgia and Medical College of Georgia have early evidence it could help patients showing signs of respiratory distress avoid extreme interventions like mechanical ventilation as well as death from acute respiratory distress syndrome. PLUS When a plant-based meat alternative company pays for the science, is it any wonder that the outcome is in their favor?
SHR # 2569 :: CBD May Help Avert Lung Destruction in COVID-19 plus BS Science Alert: Plant-based Meats Improve Some Cardiovascular Risk Factors - Dr. Babak Baban and Dr. Jack Yu - Cannabidiol, or CBD, may help reduce the cytokine storm and excessive lung inflammation that is killing many patients with COVID-19, researchers say. While more work, including clinical trials to determine optimal dosage and timing, is needed before CBD becomes part of the treatment for COVID-19, researchers at the Dental College of Georgia and Medical College of Georgia have early evidence it could help patients showing signs of respiratory distress avoid extreme interventions like mechanical ventilation as well as death from acute respiratory distress syndrome. PLUS When a plant-based meat alternative company pays for the science, is it any wonder that the outcome is in their favor?
In this episode, Dr. Scott and Tommy talk about the latest obesity epidemic statistics and projections for the year 2030. Despite the dim outlook, they reveal a simple method anyone can use to protect themselves from the trend. They give details on how a small tweak in meal timing can have a MASSIVE impact in the body. Simple, effective, and backed by research, the intermittent fasting window of 16/8 is a simple solution to a growing problem. Citations 1. Projected U.S. State-Level Prevalence of Adult Obesity and Severe Obesity 2. Effects of Eight Weeks of Time-Restricted Feeding (16/8) on Basal Metabolism, Maximal Strength, Body Composition, Inflammation, and Cardiovascular Risk Factors in Resistance-Trained Males Show Transcript: www.thefastingforlife.com/blog If you enjoy the podcast, would you please tap on the stars below and consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to bring you the best original content each week. We also just enjoy reading them! Sign up for the Fasting for Life newsletter at www.thefastingforlife.com Follow Fasting for Life: www.facebook.com/thefastingforlife www.instagram.com/thefastingforlife
Recent studies indicate that for those with cardiovascular health issues, eggs are not the villain they were once thought to be.
Episode 9 - October 2018 Topic: Diet Dialogue: Approaching Patient Conversations Using National Nutrition Data Guests: Chris Taylor, PhD, and Ashlyn Smith, PA-C Support for this episode of Vital Minds is provided by Abbott Nutrition. Resources: National Health and Nutrition Examination Survey 1999–2016 Survey Content Brochure Long Term Effects of a Lifestyle Intervention on Weight and Cardiovascular Risk Factors in Individuals with Type 2 Diabetes: Four Year Results of the Look AHEAD Trial The Look AHEAD Trial: Implications for Lifestyle Intervention in Type 2 Diabetes Mellitus Diabetes Prevention Program (DPP) USDA Food and Nutrition Services AACE 2018 DM2 Guidelines (pp. 3-4, 24) ADA Standards of Medical Care in Diabetes 2018 (pp. 47-51) Why Muscle Mass Matters Costs of Malnutrition in Institutionalized and Community-Dwelling Older Adults: A Systematic Review USDA: What We Eat in America Patient Resources: My Game Plan: Food and Activity Tracker AADE Diabetes Wellness Program Dietary Guidelines for Americans USDA MyPlateRead more ›
Impact of Physical Activity on Glycemic Control and Prevalence of Cardiovascular Risk Factors in Adults With Type 1 Diabetes: A Cross-sectional Multicenter Study of 18,028 Patients. Diabetes Care. 2015 Aug;38(8):1536-43
This Week in Machine Learning & Artificial Intelligence (AI) Podcast
In this episode, I'm joined by Google Research Scientist Ryan Poplin, who recently co-authored the paper “Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning.” In our conversation, Ryan details his work training a deep learning model to predict various patient risk factors for heart disease, including some surprising ones like age and gender. We also dive into some interesting findings he discovered with regards to multi-task learning, as well as his use of an attention mechanisms to provide explainability. This was a really interesting discussion that I think you’ll really enjoy! The notes for this show can be found at twimlai.com/talk/122.
Dr. K explains what to know and do about cardiovascular risk factors, which often contribute to cerebral small vessel disease, a common brain health problem in older adults. She covers 12 key factors to discuss with healthcare providers, and 5 top approaches that most aging adults can use, to decrease their cardiovascular risk. The post 057 How to Manage Cardiovascular Risk Factors for Better Brain Health appeared first on Better Health While Aging.
Interview with Mary G. George, MD, MSPH, author of Prevalence of Cardiovascular Risk Factors and Strokes in Younger Adults, and James F. Burke, MD, author of Are More Young People Having Strokes?—A Simple Question With an Uncertain Answer
Commentary by Dr. Valentin Fuster
In this podcast Dr Helen Noble talks to Dr Alice Ammerman, from The University of North Carolina at Chapel Hill, USA about her recent commentary published in EBN. The study commentary titled " Behavioural counselling improves physiological outcomes in those with cardiovascular risk factors” reflected on a study which addressed four topics: (1) the effect of dietary and physical activity counselling on patient health outcomes; (2) intermediate CVD-related outcomes; (3) behavioural outcomes; and (4) harms of counselling. In this podcast they explore the need for the study, its strengths and weaknesses and the implications for clinical practice.
Learn About the Positive Benefits of Taking Coenzyme Q10 and Aged Garlic Extract on Cardiovascular Risk Factors, Vascular Elasticity and Endothelial Function, and the ABCs of Being "Heart Smart"! Kirk Hamilton interviews Matthew Budoff, MD, Professor of Medicine, David Geffen School of Medicine and Director of Cardiac CT at the Division of Cardiology at the Harbor-UCLA Medical Center in Torrance, California. Dr Budoff received his medical degree from the George Washington University School of Medicine in Washington, DC and completed an internship and residency in internal medicine, and a fellowship in cardiology, at Harbor- UCLA Medical Center. Dr Budoff has authored or co-authored more than 400 research papers, six books, and 36 book chapters. Most recently, he was named to the U.S. News & World Report list of Top Doctors for 2011. He is the co-author of the paper "Beneficial Effects of Aged Garlic Extract and Coenzyme Q10 on Vascular Elasticity and Endothelial Function: The FAITH Randomized Clinical Trial" in the journal Nutrition, August 2012. Download or Open:
Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 13/19
Epidemiological studies have shown that elevated air pollution levels and day-to-day variations in air temperature are associated with increases in cardiovascular events such as arrhythmias, myocardial infarctions, and sudden cardiac death. Precursors of these events might be acute changes in heart rate, a reduced heart rate variability (HRV), and changes in the repolarization of the heart, such as QTc-prolongation as well as changes in T-wave amplitude. Furthermore, elevated levels of blood markers of inflammation and coagulation might also lead to the observed adverse cardiac health outcomes. There is already a large body of literature with regard to air pollution effects on HRV parameters and blood markers but the exact biological pathways are still unclear. Little is known about the association between temperature and HRV as well as blood markers. Moreover, potential mechanisms how air pollutants and temperature affect repolarization have received less attention. Researchers have reported that individuals with genetic predispositions or underlying diseases such as diabetes mellitus type 2 might be more susceptible to air pollution exposure. Therefore, more comprehensive investigations in these groups of individuals are necessary in order to gain a better insight in the biological mechanisms. In the first publication of this thesis, I examined the effects of air temperature on markers of inflammation and coagulation in men with coronary or pulmonary disease. A temperature decrease was associated with changes in several blood biomarkers such as platelet counts, factor VII, fibrinogen, and C-reactive protein. However, the direction and timing of the relationship differed between patients with coronary and pulmonary disease. In a second publication, I observed a prolongation of the QT-interval in association with elevated levels of particulate matter (PM) in myocardial infarction survivors. This association was more pronounced in participants with at least one minor allele of the NFE2L2 single nucleotide polymorphism (SNP) rs2364725 which is believed to be involved in the defense against oxidative stress. Furthermore, I detected immediate T-wave flattening and delayed increases in T-wave amplitude associated with elevated air pollution levels. The association between temperature and the T-wave amplitude was inversely U-shaped with highest values at 5C. In a third study among participants with diabetes or impaired glucose tolerance (IGT), I detected reduced HRV, predominantly the standard deviation of normal-to-normal intervals, in association with increases in PM and ultrafine particles. These effects were more pronounced in participants with IGT. I also observed air pollution effect modifications by SNPs supposed to influence cardiac rhythm. In conclusion, this thesis confirms and extends published results on short-term air pollution effects on intermediate markers of cardiovascular system. Furthermore, it is among the first to examine air temperature effects on blood and ECG parameters. Certain medical conditions as well as certain genetic profiles seem to make some subpopulations more susceptible to environmental stressors. The observed changes in HRV and blood markers might partly explain the reported associations between environmental conditions and cardiovascular events.
Learn About the History of Lipids and Heart Disease Risk and the State of Lipids as Cardiovascular Risk Factors in 2011 Kirk Hamilton interviews Dr. William Castelli who received a B.S. in Zoology from Yale College and a Doctor of Medicine, Surgery and Obstetrics from the Catholic University of Louvain in Belgium. Dr. Castelli joined the Framingham Heart Study in 1965 where he reorganized the Framingham laboratory to measure lipoproteins such as LDL, VLDL, IDL, HDL and sinking Pre-Beta (Lp {a}). In 1979 Dr. Castelli became the third director of the Framingham Heart Study which now includes four generations of Framingham people. Associations with three medical schools in the area have led to his teaching epidemiology and prevention of atherosclerotic cardiovascular disease for 34 years at the Harvard Medical School, 22 years at the Boston University School of Medicine and 15 years at the University of Massachusetts Medical School. He currently is the medical director of a new wellness program at the MetroWest Medical Center in Framingham Massachusetts which specializes in the aggressive management of cardiovascular risk factors. He also lectures frequently on heart disease risk assessment and treatment. Download or Open:
Background: Type 1 diabetes mellitus is a generally accepted atherogenic risk factor. The aim of this prospective longitudinal study was to evaluate changes in carotid intima media thickness (cIMT) in children and adolescents with type 1 diabetes mellitus (T1DM) using standardized methods. Methods: We re-evaluated cIMT in 70 (38 f) of initial 150 (80 f) patients with T1DM after 4 years. At re-evaluation, mean (+/- SD) age was 16.45 +/- 2.59 y, mean diabetes duration was 9.2 +/- 3.24 y and patients had a mean HbA1c of 8.14 +/- 1.06%. Results: Mean cIMT z-scores increased significantly during 4 years (0.58 +/- 0.75, p < 0.001) as well as BMI-z-score (0.41 +/- 0.81, p < 0.01), systolic blood pressure (0.77 +/- 1.15, p < 0.01) and HbA1c (0.90 +/- 1.07, < 0.001). In a linear regression model systolic blood pressure z-score at first measurement (0.02, CI: 0.01, 0.04) was a significant predictor for the mean effect on cIMT z-score. In a logistic regression model significant risk factors for an increase in IMT of >= 1.5 z-scores were BMI z-scores (OR: 3.02, CI: 1.11, 10.14), diabetes duration (OR: 1.32, CI: 1.04, 1.77) and systolic blood pressure (OR: 1.14, CI: 1.04, 1.27) at first measurement each. Conclusions: Longitudinal cIMT measurements revealed progression in subclinical atherosclerosis during a four year period in diabetic children and adolescents. Systolic blood pressure and BMI were related to cIMT increment. Control of these risk factors by lifestyle and medical intervention may prevent progression of cIMT in diabetic children.
Guest: Samuel Gidding, MD Host: Alan S. Brown, MD, FNLA What age does atherosclerosis and increased risk of heart attacks begin? Can children be at risk, and under what conditions should children's cholesterol levels be checked? Host Dr. Alan Brown discusses lipids in pediatric patients with Dr. Sam Gidding, of the Nemours Cardiac Center at the Alfred I. duPont Hospital for Children in Wilmington, Delaware, and professor of pediatrics at the Jefferson Medical College. Brought to you by:
Background: Epidemiological studies have shown that microalbuminuria is an important risk factor for arteriosclerosis, coronary heart disease and other vascular diseases in persons with type 2 diabetes. In the present study we examined the prevalence and risk factors for micro- and macroalbuminuria and examined glycemic control as well as treatment of modifiable cardiovascular risk factors in persons with known type 2 diabetes in Germany. Methods: The presented data were derived from the `KORA Augsburg Diabetes Family Study', conducted between October 2001 and September 2002. Participants were adults aged 29 years and older with previously diagnosed type 2 diabetes (n = 581). Microalbuminuria was defined as an albumin-creatinine ratio of 30 to 300 mg/g, and macroalbuminuria as an albumin-creatinine ratio of more than 300 mg/g. Results: Microalbuminuria was revealed in 27.2% and macroalbuminuria in 9.0% of the 581 included diabetic persons. Multivariable regression analysis identified HBA1c, duration of diabetes, systolic blood pressure, serum creatinine, smoking and waist circumference as independent risk factors associated with albuminuria (micro- or macroalbuminuria). Relatively few persons with type 2 diabetes achieved treatment targets of HbA1c < 7% (46.6%), total cholesterol < 200 mg/dl (44.1%), and LDL cholesterol < 100 mg/dl (16.0%). Optimal HDL cholesterol values (> 45 mg/ dl in men, > 55 mg/ dl in women) were found in 55.8%, and blood pressure values < 130 and < 85 mmHg in 31.3% of the persons Conclusion: Albuminuria is common among German persons with known type 2 diabetes. Despite evidence-based guidelines, only a small proportion of type 2 diabetic persons achieved the recommended levels of glycemic control and control of cardiovascular risk factors.