Podcast appearances and mentions of ace inhibitors

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sacubitril/Valsartan vs ACE Inhibitors or ARBs: A Systematic Review and Meta-Analysis of Randomized Trials

We're back, after a brief hiatus! Today we talk about duration of therapy for bacteremia, Factor XI inhibition for atrial fibrillation, whether to stop ACEi or ARB before elective surgery, and whether GLP-1 agonists are beneficial in heart failure with preserved ejection fraction. Go to minute 7:30 to skip the banter. 7 vs 14 Days of Antibiotics for Bacteremia (BALANCE)Abelacimab vs Rivaroxaban for Atrial Fibrillation (AZALEA-TIMI-71)Asenduxian vs Apixaban for Atrial Fibrillation (OCEANIC-AF)ACEi or ARB Discontinuation Before Surgery (STOP or NOT)Tirzepatide for HFpEF and Obesity (SUMMIT)Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R

$5 Q-BANK: https://patreon.com/highyieldfamilymedicine Intro 0:30, Hypertension classifications 1:45, Lifestyle modifications 3:00, Thiazide diuretics 4:16, ACE Inhibitors and ARBs 5:59 Calcium channel blockers 8:15, Beta blockers 9:36, Mineralocorticoid receptor antagonists 10:49, Goal-directed medical therapy 12:49, Resistent hypertension 15:37, Other antihypertensives 16:38, Hypertensive emergency 20:33, Hypertension in pregnancy 23:00, Primary hyperaldosteronism 24:38, Renal artery stenosis 26:24, Cushing syndrome 27:22 Pheochromocytoma 28:53, Obstructive sleep apnea 30:26, Coarctation of the aorta 31:30, Practice questions 32:30

This episode covers the physiology of the renin-angiotensin-aldosterone system.Written notes can be found at https://zerotofinals.com/physiology/endocrine/reninangiotensinaldosteronesystem/ or in the endocrinology section of the 2nd edition of the Zero to Finals Medicine book.The audio in the episode was expertly edited by Harry Watchman.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-380 Overview: This episode brings you a comparison of thiazide diuretics, angiotensin-converting enzyme (ACE) inhibitors, and calcium channel blockers on cardiovascular outcomes, stroke, and all-cause mortality. Gain evidence-based insights to help you make informed choices for your patients' care. Episode resource links: Circulation . 2024 Jan 23;149(4):279-289. doi: 10.1161/CIRCULATIONAHA.123.066485. Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-380 Overview: This episode brings you a comparison of thiazide diuretics, angiotensin-converting enzyme (ACE) inhibitors, and calcium channel blockers on cardiovascular outcomes, stroke, and all-cause mortality. Gain evidence-based insights to help you make informed choices for your patients' care. Episode resource links: Circulation . 2024 Jan 23;149(4):279-289. doi: 10.1161/CIRCULATIONAHA.123.066485. Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

“The search for daunorubicin's sister really led to this discovery of doxorubicin, which is an analog with much greater activity. The discovery of doxorubicin can be coined kind of as, ‘one of the best drugs born in Milan, Italy.' And after that, a few analogs were developed and tested, and two that we currently use today, are idarubicin and epirubicin,” Puja Patel, PharmD, BCOP, clinical oncology pharmacist at the Delnor Hospital Northwestern Medicine Cancer Center in Geneva, IL, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a discussion about anthracyclines and other antitumor antibiotics. This episode is part of a series about drug classes, which we'll include a link to in the episode notes.  You can earn free NCPD contact hours after listening to this episode and completing the evaluation linked below.   Music Credit: “Fireflies and Stardust” by Kevin MacLeod  Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD), which may be applied to the nursing practice, oncology nursing practice, symptom management, palliative care, supportive care, or treatment ILNA categories, by listening to the full recording and completing an evaluation at myoutcomes.ons.org by January 26, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of NCPD by the American Nurses Credentialing Center's Commission on Accreditation.  Learning outcome: The learner will report an increase in knowledge of anthracyclines and antitumor antibiotics.  Episode Notes  Complete this evaluation for free NCPD.   Oncology Nursing Podcast: Pharmacology 101 series  ONS Voice oncology drug reference sheets  IV Cancer Treatment Education Sheets  ONS Voice articles:  The Evidence Is Building for ACE Inhibitors in Anthracycline-Associated Cardiotoxicity  Outpatient Oncology Drug Series: Doxorubicin Is the Infamous Red Devil  Clinical Journal of Oncology Nursing articles:  Nursing Alchemy: Transforming R-CHOP Information Into Essentials  Dyspnea: Common Side Effect  Cardiac Toxicity: Using Angiotensin-Converting Enzyme Inhibitors to Prevent Anthracycline-Induced Left Ventricular Dysfunction and Cardiomyopathy  Oncology Nursing Forum article: Symptom Clusters in Lymphoma Survivors Before, During, and After Chemotherapy: A Prospective Study  ONS Huddle Card: Antitumor Antibiotics  Additional healthcare professional resources:  Blindspot: Hidden Biases of Good People  Harvard University Implicit Association Test  OncoPharm Podcast  ASCO Education Podcast  Additional patient resources:  National Comprehensive Cancer Network patient resources  National Comprehensive Cancer Network patient webinars  National Cancer Institute resources for patients   To discuss the information in this episode with other oncology nurses, visit the ONS Communities.   To find resources for creating an ONS Podcast Club in your chapter or nursing community, visit the ONS Podcast Library.  To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org.  Highlights From Today's Episode  “Anthracyclines are kind of categorized as topoisomerase II inhibitors, and these agents are very powerful in that they have—it's really like three drugs in one—they have various mechanisms.” TS 3:55  “We need to create a stable environment, and so we actually cut one of the cords, and that's exactly what topoisomerase is doing. It's cutting one of the DNA strands. And in this case, it's cutting two strands, and that's why it's called topoisomerase II, so it's cutting both of the strands. It's cutting the DNA, releasing some of that tension, allowing for replication, and then rejoining that portion. So, it's a very important enzyme, and it'll go about doing this for the entire strand of DNA.” TS 4:50  “The other second mechanism is kind of the effect on DNA. So, you'll come across reading the term ‘DNA intercalation.' So, what does that word mean? When you take the word ‘intercalate,' the definition of it means ‘intrusive inserting of something in an existing series or sequence.' The analogy that I could think of here is simple: It's thinking about too many passengers squeezing in the backseat of your car. There could be safety issues, there's weight issues, there's instability maybe while driving. And that's what this doxorubicin is doing. It's sliding right in between the base pairs of the DNA double helix, destroying hydrogen bonds between those two bases, which then change the shape of that double helix. And by changing the shape, topoisomerase II, which we just talked about, can no longer go in and bind to DNA. It can't relax that super coil. And so, DNA synthesis doesn't happen.” TS 6:02  “So, the main toxicity that our listeners might be familiar with is cardiotoxicity. And also with cardiotoxicity, breaking it down a little bit, there's an onset that occurs during treatment or even years to decades, and that's kind of this delayed cardiotoxicity. Signs and symptoms of acute cardiotoxicity could vary from EKG changes present as tachycardia, tachyarrhythmia. Delayed cardiotoxicity is anything from heart failure to left ventricular ejection fraction decrease.” TS 9:41  “We're worried about heart failure in these patients. So, we might see EKG changes, we might see LVEF [left ventricular ejection fraction] changes, and we're kind of tracking these agents based on what is called cumulative dose tracking or lifetime dose. So, all of these agents have specific lifetime maximums that we need to be aware of.” TS 14:53  “So, smoking, hypertension, diabetes, dyslipidemia, obesity, or you're older in age, or perhaps you have a compromised cardiac function—you're at greater risk for developing these cardiotoxicities. An example that I've had in my clinic is I've identified some of these patients that have these risk factors, and we go into a little bit more aggressive monitoring for the echocardiogram or MUGA [multigated acquisition]. And when we put in those orders, we often get denials from insurance. We submit the guidelines in, kind of, appeals to help those patients kind of proactively realize if we're putting them in a greater cardiac risk.” TS 15:47  “One of the biggest things is for nurses to kind of look over their policies for administration for vesicants and specifically checking blood return for these agents, because many of them are given, you know, IV push. So, checking blood return every 2–5 ml is really important to make sure that you are in the right space. And then these agents, some of them can also be given continuously. So, you're thinking about, first of all, you should have a central line in for these agents because they're vesicants. But if it's being given continuous, there is something that's called anthracycline streaking, and it's not the same as an extravasation. So, I think being able to decipher the difference between the two is really, kind of, comes with experience.” TS 20:36  “I think awareness is really essential. And thankfully, you know, thankfully or not, I guess, you were with the patient for this entire time, right? Because you're pushing every 2–5 ml, you're checking. So, it's a very kind of intimate experience in and of itself. So, I think just being very vigilant is very important.” TS 22:24  “So, to talk about bleomycin here, for example, kinetically, two-thirds of this drug is eliminated renally. And so, we would think that there would need to be renal adjustments if there's renal changes. So, for creatinine clearance greater than 50, there are no renal dose adjustments. But after that, every 10 ml per minute decrease in GFR [glomerular filtration rate], there are dose reductions that are required. And this drug, in particular, has a lot of gradations in terms of renal dysfunction that I've seen.” TS 27:30  “Thinking about bleomycin, it's IV over 10 minutes, and you want to think about the lifetime maximum dose. So, when you are working up your patient, that's something to kind of think about. Dactinomycin is highly emetogenic, so making sure that there's antibiotics on board. It's also a vesicant, so thinking about vesicants precautions. Cold compresses is how you would help treat that if there is an extravasation.” TS 33:14   “I think trust is the foundation oncology really because we are asking our patients to do so many things outside of our infusion center, picking up medications, taking medications, calling us about signs and symptoms, going and getting all these imaging know. So, if there isn't that foundation of trust, having this perfect curative treatment plan may be more challenging to really be carried out.” TS 38:06  “We've developed these very powerful agents, and they're non–cell specific. So, I think the next step would be, how can we reformulate them to make them less toxic and provide more of a targeted approach? And so, perhaps an antibody-drug conjugate that is specifically attacking the lymphoma or the breast cell can deliver this chemotherapy with a cytotoxic payload is there in the horizon.” TS 39:07  “I think the misconception that ‘I will develop heart damage' is really important. Doxorubicin has the infamous name of the red devil, but I think it's important to let your patients know that heart failure increases with cumulative dosing. You know, talking to them about 300 mg/m2 is associated with a 1.5% heart failure risk. Whereas going all the way across to 500 mg/m2, now you're looking at 6%–20% probability of developing heart failure.” TS 42:30  “I think taking the time and understanding the literature. Typically, we don't start these agents with LVEF less than 50–55. There's some great review articles in JCO [Journal of Clinical Oncology] that kind of define what cardiomyopathy decrease looks like and decreases in LVEF over 10% to a value below the institutional limit of normal, I think, is a nice point to have as a value, a number to kind of work with.” TS 43:53  “Working with your nurse educator and leader to help achieve OCN®, oncology certified nurse, certification is really important. And I think live simulated experiences are really beneficial, maybe even looking at extravasations or having an infusion-related reaction, because here in the acute setting, we're really kind of in this like responsive mode. But if we practice, we can respond more deliberately and more calmly.” TS 45:05 

CJASN Editor-in-Chief Rajnish Mehrotra interviews 2023 CJASN Trainee of the Year winner Rosa D. Wouda on her article, "Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements."

On this episode, I discuss aliskiren pharmacology, adverse effects, drug interactions, and much more. Aliskiren should not be used with ACE Inhibitors or ARBs. I discuss why that is in this episode. Aliskiren has a long enough half-life at approximately 24 hours so it is recommended to only take this once daily. Hyperkalemia is a major concern with aliskiren. It is important to monitor potassium levels and renal function.

The second of the RAAS system blockers! Very similar to the ACE Inhibitors with a little twist. "And all the Sartans assembled........."

Here we are with the ACE Inhibitors!! Yet another versatile class of drugs and oh how smart those scientists were to discover them. Listen up.

Download the cheat: https://bit.ly/50-meds  View the lesson: https://bit.ly/LithiumLithonateNursingConsiderations      Generic Name lithium Trade Name Lithizine Indication mania Action alters cation transport and neurotransmitter reuptake Therapeutic Class Mood Stabilizer Pharmacologic Class none Nursing Considerations • do not administer with NSAIDs • monitor drug blood levels frequently • may cause seizures, arrhythmias, fatigue, confusion, nausea, anorexia, hypothyroidism, tremors • Ace Inhibitors may increase serum levels • instruct patient to maintain adequate fluid intake • therapeutic level: 0.5-1.5 mEq/L

For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:  ·Newsletter Sign Up·Jubilee website·PrevMed's website·PrevMed's Rumble channel·PrevMed's YouTube channel·PrevMed's Facebook page·PrevMed's Instagram·PrevMed's LinkedIn·PrevMed's Twitter ·PrevMed's Pinterest

PODCAST HIGHLIGHTS: 02:53 MEDICATION and NUTRIENT REPLACEMENT 04:52 ACE Inhibitors 07:11 SELF MONITORING 07:56 ACE INHIBITORS SELF CARE 12:25 NUTRIENT DEFICIENCIES 14:50 Vitamin D TESTING 15:56 BETA BLOCKERS 25:19 WAYS TO LOWER BLOOD PRESSURE 26:50 HIGH HEMOGLOBIN 28:12 RELAXATION 31:48 BIOFEEDBACK DEVICES 34:45 LOWER INFLAMMATION 37:03 HERBS & SUPPLEMENTS 39:27 PEMF MAT https://youtu.be/J57LyNxHK08 Transcript from...... Continue Reading →

ACE Inhibitors, Beta Blockers, ARB, Calcium Channel Blockers & many more.

Episode 33: Prophylactic Series: Why Telmisartan in Enhanced Competitors?   In this episode of J3 University, Luke and I discuss the risk of PED usage and how blood pressure medications serve as a hard reduction strategy. All blood pressure medications are covered and specially answering why Telmisartan is spoken about more frequently.      Timestamps   NPC Nationals and Pro Card Wins- 00:00:08   Enhanced Bodybuilder Risk- 00:03:10   Renin-angiotensin-aldosterone system, Classes of Medication- 00:07:52   ARB vs ACE Inhibitors- 00:13:31   Telmisartan Actions/Benefits- 00:15:15   Blood viscosity/blood dump, Improvement in lab work- 00:19:14   Access to medication- 00:24:36   Deploying for reduction in Water retention- 00:29:46   Where to find more info- 00:34:00   J3 UNIVERSITY: http://j3university.com FACEBOOK: https://www.facebook.com/J3-University-103894631667528 INSTAGRAM: https://www.instagram.com/johnjewett3/   Luke Miller INSTAGRAM: https://www.instagram.com/noswitchfitness/?hl=en Luke Miller coaching: https://noswitchfitness.com/contact/          

This episode will provide information about Angiotensin Converting Enzyme inhibitors(ACE inhibitors) and Angiotensin Receptor Blockers(ARB's) and their effect in treating High Blood Pressure. It will explain, in understandable language, how and where these medications work, how and when to take them, and what are the common side effects and cautions to be aware of. A transcript of this episode will be available for printing and sharing. All links to references used will also be made available. 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-253   Overview: ACE (angiotensin-converting enzyme) inhibitors and ARBs (angiotensin receptor blockers) are both recommended as first-line treatments for hypertension. ACE inhibitors have known side effects, such as cough, that are frustrating for many patients, while ARBs appear to have less annoying side effects. This podcast will review a recently published retrospective, comparative cohort study comparing the effectiveness and safety of ACE inhibitors vs ARBs in the first-line treatment of hypertension.   Episode resource links: Hypertension. 2021;78:591–603. DOI: 10.1161/HYPERTENSIONAHA.120.16667   ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/ NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2018;71:e127–e248. doi: 10.1016/j.jacc.2017.11.006 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-253   Overview: ACE (angiotensin-converting enzyme) inhibitors and ARBs (angiotensin receptor blockers) are both recommended as first-line treatments for hypertension. ACE inhibitors have known side effects, such as cough, that are frustrating for many patients, while ARBs appear to have less annoying side effects. This podcast will review a recently published retrospective, comparative cohort study comparing the effectiveness and safety of ACE inhibitors vs ARBs in the first-line treatment of hypertension.   Episode resource links: Hypertension. 2021;78:591–603. DOI: 10.1161/HYPERTENSIONAHA.120.16667   ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/ NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2018;71:e127–e248. doi: 10.1016/j.jacc.2017.11.006 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Commentary by Dr. Valentin Fuster

Heart donations safe from illicit drug users. Heart failure diagnosis missed earlier. Side effects of ARBs vs ACE Inhibitors. WATCHMAN FLX safety and performance.

In this episode, we review the high-yield topic of ACE Inhibitors from the Renal section. --- Send in a voice message: https://anchor.fm/medbulletsstep1/message

Before we ask a patient to take any drug we should be confident that the benefits outweigh the risks. This involves considerations like duration of therapy and whether the drug is being used to treat a disease versus prevent it. But even more important is an understanding of how the pharmacology of the drug matches up to the pathophysiology of the disease. The better we understand both, the better we'll be at deciding when to use any drug for any disease. In todays episode we apply these tenets of drug therapy to a common question, "does my patient with diabetes need to be on an ACEi or ARB?" To answer that question, we'll discuss the merits of drugs for disease prevention versus disease treatment. The use of risk factors for disease may or may not be sufficient to justify drug therapy. An LDL cholesterol of 220 is sufficient to initiate cholesterol lowering therapy. But is diabetes a sufficient reason to initiate an ACEi or ARB? We'll figure that out....and whether or not the answer surprises you, we'll learn things along the way that will be useful in virtually all settings of applied pharmacotherapy.

We'll cover an update on the use of ACE inhibitors and ARB drugs amid COVID-19, particularly on the "double-edged sword" nature of the two BP medications. Here's the link to the JAHA article: https://www.ahajournals.org/doi/10.11.... We'll also cover our telemedicine program for non-emergency care, other COVID-19 updates, vitamins C and D3, DIC (disseminated intravascular coagulation), prediabetes, and calcium score. For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:  ·PrevMed's website·PrevMed's YouTube channel·PrevMed's Facebook page

In this video, we discussed "social" vs. "physical" isolation in the midst of COVID-19. Plus updates on ACE Inhibitors, zinc supplements and ionophores, chloroquine and hydroxychloroquine, reinfection, coronavirus testing, and in-home medical care.For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:  ·PrevMed's website·PrevMed's YouTube channel·PrevMed's Facebook page

In this live session, we discussed the current CDC policies regarding COVID-19 testing (very little of it) and "social isolation" vs. what's worked in other countries (greatly expanded testing, case finding, and quarantine). Plus, updates on ACE Inhibitors, zinc supplements and ionophores, chloroquine and hydroxychloroquine, HIV antivirals and coronavirus, reinfection, coronavirus test, and in-home medical care (telemedicine).For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:  ·PrevMed's website·PrevMed's YouTube channel·PrevMed's Facebook page

Children are also affected by COVID-19, and they are part of the transmission. In this video, we'll talk about COVID-19 and children, as based on this NEJM article: https://www.nejm.org/doi/full/10.1056...​. Plus, I'll provide updates and answers about ACE Inhibitors; baby aspirin and NSAIDs; zinc supplements, quercetin, and ionophores; chloroquine and hydroxychloroquine; and the clinical trial of HIV antivirals Lopinavir & Ritonavir against the coronavirus.For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:  ·PrevMed's website·PrevMed's YouTube channel·PrevMed's Facebook page

Let's talk about new updates on the science of COVID-19.   (1) A study published in Lancet has been hypothesizing increased COVID-19 risk with the intake of ACE inhibitors or ARB:  https://www.thelancet.com/journals/la...​.(2) The European Society of Cardiology (ESC), however, stated that doctors shouldn't change patient's use of ACE inhibitor and ARB:  https://www.escardio.org/Councils/Cou...​. We'll also talk about coronavirus testing, zinc supplements, antimalarial drugs chloroquine, and hydroxychloroquine, social isolation, and telemedicine as measures against the current COVID-19 pandemic. For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:  ·PrevMed's website·PrevMed's YouTube channel·PrevMed's Facebook page

Show note at pharmacyjoe.com/episode600 . In this episode, I ll discuss the mechanism of interaction between ACE inhibitors and angiotension II. The post 600: What is the mechanism of interaction between ACE inhibitors and angiotension II? appeared first on Pharmacy Joe.

High blood pressure is often called “the silent killer” due to the fact that so many people don't realize they have high blood pressure until it is too late.High blood pressure is often called “the silent killer” due to the fact that so many people don't realize they have high blood pressure until it is too late.  Persistently high blood pressure can lead to kidney disease, dementia, heart disease, stroke, arterial disease, and vision problems. Conventional medicine uses medications for high blood pressure such as Diuretics, Beta Blockers, ACE Inhibitors, Calcium Channel Blockers, or Aldosterone Blockers. These medications are often effective. But can also cause many side effects such as heart muscle dysfunction, asthma, low heart rate, irregular heartbeat, dry mouth, kidney dysfunction, swelling of ankles, and rapid heartbeat. These negative side effects can often be avoided by following a more natural approach based on excellent scientific evidence. Listen to this episode for foods to eat, foods to avoid, tips for managing stress, the importance of sunshine, and more!You can find Aubrey on her website, LinkedIn, or Instagram And you can find Dr. Bens on his website

Today we’re taking a deep dive into angiotensin converting enzyme inhibitors (otherwise known as ACE inhibitors). In this podcast episode you will learn:  The RAAS pathway (understanding this is crucial to understanding how and why ACE inhibitors work!) How to easily spot an ACE inhibitor What conditions ACE inhibitors are used to treat Adverse effects of ACE inhibitors...including one that can be life threatening! Are you as obsessed about patient safety as I am? Learn how to BULLETPROOF your medication administration here: https://straightanursing.ck.page/fc69f2501b Are you looking for an awesome community to support you on your nursing school journey? Join my Facebook group, Thriving Nursing Students and instantly have more than 14K new friends :-) https://www.facebook.com/groups/thrivingnursingstudents Read the show notes and see references here: https://www.straightanursingstudent.com/ace-inhibitors/

Have you been trying to keep up with the COVID literature, but too shattered after work these days to read anything except the local take out menu?Your ears are in the right place, we help you get up to date on what you need to know in COVID-19, including:TOCILIZUMAB: Why it's been approved and when you might be using it.ICU DELIRIUM: Why you should put the benzos away and get the iPad out.ASYMPTOMATIC TRANSMISSION:What percentage of your family actually had COVID at Christmas?VENOUS THROMBOEMBOLISM:  Wondering why everyone is messing around with the prophylaxis dose?OXYGEN: is it safe in the early 90's?PRONING: what's the point and do patients actually do it?ACE INHIBITORS: can we finally declare them safe in COVID?

Trauma System GuidelinesInterview with the Salem Hospital Trauma System CoordinatorLisinopril, ACE Inhibitors, AngioedemaEmployee Spotlight - Falck EMT's and Paramedic School during COVIDCoagulation Cascade, PH Balance and Permissive Hypotension and Saline in TraumaMusic supplied by various artists on:http://www.Pixabay.com

In our constant belief that we are at war with nature and all of the germs, we are killing ourselves ever faster and it is ludicrous and sad because we have twenty, thirty years of data on the microbiome to know that it's the microbiome that prevents cancer, autoimmune disease, depression, anxiety, sleep disorders, and infertility; it's all the microbiome. Yet somehow, from this ridiculous fear story, suddenly the whole world including scientists are okay with killing every organism on earth. COVID19 is just a very sad, low-vibration event. - Dr. Zach Bush   More than ever, a voice like Dr. Zach Bush needs to be heard and because this has been our most popular episode this year, we are doing a special release of it today. The Radical Truth About COVID-19 For all of us, 2020 has been in many ways the year of the phoenix rising from the ashes. Right now we are still watching it burn down to the ground. So we invite you to listen to Dr. Zach Bush including 5 other guests in our CV19 Truth Series: Protecting Your Health Freedom This special edition 6-part CV19 Truth Series: Protecting Your Health Freedom podcast with host, Josh Trent, spotlights the best and most trusted information you will find in the online wellness world when it comes to taking your health and wellness into your own hands. Get 15% off your CURED Nutrition order with the code WELLNESSFORCE   ---> Get The Morning 21 System: A simple and powerful 21 minute system designed to give you more energy to let go of old weight and live life well.   JOIN THE FACEBOOK GROUP | *REVIEW THE PODCAST*   Wellness Force Radio Episode 345 Triple board-certified physician, Founder and CEO of ION*Biome and Executive Producer for the docu-series, Farmer's Footprint, Dr. Zach Bush, explains why COVID19 actually isn't a respiratory virus, explores humanity's awakening in the global shutdown, how spraying pesticides and insecticides has increased COVID19's impact and the use of hydroxychloroquine and cyanide poisoning kits against COVID19.   Is the approach to healing COVID19 patients with respirators all wrong? Discover what tools and methods might be the key to help heal COVID19 patients efficiently and quickly.   ION*Biome ***Get 15% off of your ION*Biome order with the code JOSH1KS  ION*Gut Health supports the body’s production of beneficial enzymes through redox signaling (cellular communication). Those beneficial enzymes support the tight junctions (the seals between cells) in our gut lining – the barrier protecting us from toxic substances like glyphosate and gluten while allowing the entry of beneficial nutrients. Keeping Your Gut Healthy It’s a critical barrier to keep strong so that a vibrant microbiome can flourish. Good health depends entirely on gut health because a lot more than digestion happens in the gut. It’s also where proper immune system function begins and the majority of our neurotransmitters, such as serotonin, are created. Say yes to ION*Gut Health and you are saying yes to optimal gut-brain connectivity and feel-good transmissions, protection from the toxins we face every day in our air, water, and food, immune function, digestive wellness, and supported gluten tolerance. ***Discount code cannot be applied to subscription orders Listen To Episode 345 As Dr. Zach Bush Uncovers:   [1:30] Humanity's Awakening In The Global Shutdown Dr. Zach Bush ION*Biome 344 Leslie Manookian Dr. Ben Lynch: Dirty Genes & COVID19 Joe Rogan's great media revolution, now brought to you by Spotify CURED Nutrition Zach Bush, MD On A Pandemic Of Possibility - Rich Roll Farmer's Footprint Intrinsic Health Series M Clinic The incredible work Dr. Zach has done to further improve our connection to the earth. How Mother Nature has designed herself so that when there is an extreme event, she responds with more life and biodiversity. Exploring what the virus really is and other past coronaviruses. How big data housing sites like Amazon are now able to know when a woman is pregnant even before she knows. Big data knows you’re pregnant (and that’s not all) How humanity is having a quickening as we enter this global shutdown due to the coronavirus. Why we needed this pause as we're in this metaphorical 'womb' even if it is not gentle on us. Ramifications from debt, substance abuse, to home abuse that have increased during the lockdown of the country. How human behavior has become a virus to Mother Earth and COVID19 is allowing her to heal. Why coronaviruses aren't anything new; we've seen them before for hundreds of years.   [16:00] Why COVID19 Actually Isn't A Respiratory Virus Looking at the stats of COVID19 and the fact that patients do not have a fever, do not have a low white blood cell count and do not have any change in their respiratory rate to conclude that COVID19 is a respiratory virus. What COVID19 actually is: a toxin poisoning to the red blood cell to a small percentage of people around the world in the cities with the highest rates of air pollution. Similarities between COVID19 symptoms and someone who has had cyanide poisoning; not pneumonia. (19:00) The importance of medical staff realizing that this is not some mysterious virus they should be afraid of as variants of it have already been introduced to humans in the past. How pharmaceuticals create an imbalance and put people at risk for cardiovascular disease, kidney disease, and diabetes during this "COVID19 pandemic." (24:00) The two drugs that the AMA demands be used to treat those three diseases above: ACE Inhibitors and Statin plus the fact that ACE Inhibitors cause the main COVID19 symptom, a cough, as it sensitizes the lung. Unpacking how exactly pharmaceuticals make people more susceptible to illness as the COVID19 virus is attached to other toxic particles in the air.   [25:00] How Spraying Insecticide Has Increased COVID19's Impact How our mortality significantly went up this year due to the toxicity of the planet with all of the pollution and chemicals dumped into the environment. Why spraying insecticide and toxic chemicals all over and into the air to try to sterilize the environment has increased COVID19's impact on humans. The importance of understanding that we are killing ourselves faster by harming the environment because our natural microbiome is what prevents disease and disorders. How to get out of the way of nature and just be in harmony with it for her health and our own as she continues to serve us. The importance of understanding the second law of thermodynamics: the total entropy of an isolated system can never decrease over time, and is constant if and only if all processes are reversible. (27:00) How the second law of thermodynamics applies to depression, disease, spirituality, business, economics, politics, and more. The fact that viruses are all around us: in our land, air, and ocean plus why they are not our enemies and we would be long gone thousands of years ago if they were. (30:00) The immense economic shift as the biggest consolidation of wealth (in just a couple of hands) in human history takes advantage of the COVID19 hype and fear. Price-Pottenger The Weston A. Price Foundation 321 Sally Fallon Morell & Hilda Labrada Gore   [31:00] Use of Hydroxychloroquine And Cyanide Poisoning Kits Against COVID19 Unpacking the fact that Wuhan has the most damaged ecosystem on the planet with all of the glyphosate being sprayed and has the biggest production of chemical raised pork thus this toxic stew of their microbiome is sending out an important genomic update to the rest of the world. Similarities between SARS and COVID19 symptoms including the approach to stopping them. What a hypoxic injury is as cyanide and other toxins enter red blood cells thus making the use of a respirator useless. (33:00) Unpacking why COVID19 patients are not dying from a lack of respiratory capacity, lack of oxygen in the atmosphere, or lack of oxygen in the respirator machine but from their lack of oxygen-carrying capacity. The importance of treating a COVID19 patient's hemoglobin; not the respiratory system because this is about healing a blood toxin; not a respiratory virus. How hydroxychloroquine changes the shape of the red blood cell and could actually be one of the very few medicines to increase the body's capacity to carry oxygen. The powerful impact that could happen to treat COVID19 in minutes when we use a simple cyanide poisoning kit that every hospital has vs having patients weeks on a respirator that might not even help them. (35:00)   [41:00] The Man-Made Environmental Devastation Created On Farms How Mother Earth is doing throughout all of this as she tries to breathe through her soils and oceans. The devastation that our planet has gone through including the impact of Roundup being sprayed everywhere. Soil Health Academy Dr. Allen Williams This is Your Brain on "Food Chemistry" How overplowing a field kills the mycelia or life beneath the topsoil thus causing it to lose important nutrients. Why we'll continue to see more coronaviruses impacting humanity as our air quality continues to suffer from CO2, methane, PM2.5, and other greenhouse gases. (47:50) The fact that PM2.5 is the least of our concerns if we realize that the oceans continue to take more and more CO2 and acidify which would wipe out 85% to 97% of life on earth. How we've gotten to the point of being in the midst of the planet's 6th extinction as we've already wiped out 50% of our biology and accelerating. The incredible new life that will be born on this planet when we really start to care about the planet and stop our harmful behavior. Unpacking the grand misperception that America is feeding the world when it's really just 30% as we continue to spray out chemicals onto all of our crops that have adopted mega farming. The reality that 70% of 7 billion people on earth are fed by traditional farming practices in poor countries with small amounts of farmland as farmers are abused by economic rules and lose out to the big corporation competition. How to directly help farmers in your community by buying CSA labeled foods.   [59:00] ION*Biome & The Gut-Brain Access His product, ION*Biome, and how it helps to improve our gut-brain access for great physical, emotional, and mental health. Exploring what REDOX science is: Reduction and Oxidation and its impacts on our health. His past and current research on cancer, healing the body, and how he came to create ION*Biome. Unpacking how our exosomes of genetic information from our genome could change behavior just like a virus of other cells. Breaking down our genetic DNA and RNA in relation to bacteria and fungi in our environment plus the food we just ate that's updating our genome. The fact that we have microbiome all throughout our bodies and even in the brain. Our natural biological methodologies for cellular communication across life forms at a deeper level. Exploring time, space, and this continuous vibration of the electromagnetic field that connects all of us. How we manifest events around us as the body absorbs and sends out intentions or information to the universe.   [1:16:00] Connecting The Head & The Heart Organizing our priorities to be able to be there for the people in our lives that mean the most to us. Why there is an opportunity to grow and be more when we feel disappointed that we aren't able to be present for others. How we get so caught up in life that we forget to pause and give gratitude for everything we experience and are as humans. The true calling of physicians and health care workers plus his personal message for them. Exploring the intelligence of the physical and spiritual worlds in our universe. Why a microscopic boundary is the beginning of self-identity and healthy macro boundaries: spiritual and emotional. How to let go and surrender by stop holding onto everything you believe from the roles you have played to the identities you've taken on. Patrick Gentempo The deep spiritual conversation he was gifted to have with Patrick Gentempo. Unpacking Patrick Gentempo's message: Humanity is dying largely because we keep thinking that the fabric of life is love; the fabric of the universe we live in is beauty. Love is not a thing, action, or result; love is the experience of witnessing beauty. Why we can't manifest love; all we can do is see the beauty and react to that. Through that, we will be a vessel of love. Explaining why you don't lack self-love; you just haven't given yourself the breath and time to find your own beauty. Jenn Perell Bush M21 Wellness Guide Wellness Force Community Power Quotes From The Show How To Improve A COVID19 Patient's Oxygen-Carrying Capacity   "It turns out that the main thing hydroxychloroquine does is change the shape of the red blood cell. Malaria is a parasite that attacks the red blood cell and so hydroxychloroquine, as it turns out, is one of the few medications someone could reach for to help improve the oxygen-carrying capacity of the blood. Now there's a much more efficient approach called a cyanide poisoning kit that takes just three quick injections to change the shape of the hemoglobin into methemoglobin and it does fine. We can treat a COVID19 patient with a simple cyanide poisoning kit that every hospital has in a matter of minutes rather than weeks on a respirator where the patient is dying from pneumonia." - Dr. Zach Bush   Becoming A Vessel Of Love "We don't have to manifest love; in fact, we cannot manifest love. All we can do is see beauty and react to that. Through that, we will be a vessel of love and we will pour love through ourselves not because we know how to love but because we can recognize beauty. So, for everyone trying to struggle with why you don't have self-love, it's not because you don't love yourself, it's because you just haven't given yourself the breath and the time to find your own beauty. So, find that beauty, dig in, and you're going to be able to love like you've never known before." - Dr. Zach Bush     The Toxicity Of Our Chemical Fears, Response, & Behavior "We're seeing a lot of people dying from heart disease, cancer, and autoimmune conditions right now. Our mortality went up this year significantly because of the toxicity of the planet. We've never dumped more chemicals than we have in the last year and I don't think it's surprising necessarily that the US is seeing some of the highest mortality right now because as soon as we thought this was a virus killing us, we went and sprayed insecticide and toxic chemicals into the air all over South Korea and China. All of those toxins then went airborne and ended up in cities like Seattle and New York a couple of weeks later. That band of air that is traveling across the globe all the time is carrying the toxicity of our chemical fear and response to a toxin that was developed from our chemical behavior of transportation and energy sectors." - Dr. Zach Bush     How Does COVID-19 Actually Impact Us? "Our patients are dying from a lack of oxygen-carrying capacity not a lack of respiratory capacity or lack of oxygen in the atmosphere or lack of oxygen in the respirator machine. They're dying because we're not treating the hemoglobin." - Dr. Zach Bush   Links From Today's Show  CURED Nutrition ION*Biome 344 Leslie Manookian Dr. Ben Lynch: Dirty Genes & COVID19 Zach Bush, MD On A Pandemic Of Possibility - Rich Roll Joe Rogan's great media revolution, now brought to you by Spotify Farmer's Footprint Intrinsic Health Series M Clinic Leave Wellness Force a review on iTunes Big data knows you’re pregnant (and that’s not all) Price-Pottenger The Weston A. Price Foundation 321 Sally Fallon Morell & Hilda Labrada Gore Soil Health Academy Dr. Allen Williams This is Your Brain on "Food Chemistry" Patrick Gentempo Jenn Perell Bush M21 Wellness Guide Wellness Force Community Dr. Zach Bush Facebook Twitter Instagram YouTube   About Dr. Zach Bush Dr. Zach Bush is a physician specializing in internal medicine, endocrinology, and hospice care. He is an internationally recognized educator and thought leader on the microbiome as it relates to health, disease, and food systems.     CURED Nutrition Get 15% off your CURED Nutrition order with the code WELLNESSFORCE It's taken me over a year to find the right hemp and CBD company to introduce to the Wellness Force Community and I could not be more thrilled that it's CURED Nutrition! CURED Nutrition is a movement inspired by nature and grounded in a shared desire to leave a lasting impression on you, our community, and this world. Together, they're a collective of heart-centered human beings who are inviting you – the conscious creatives, dreamers, and healers – to join their family. Learn how CURED hemp and CBD products can enhance your daily wellness routine. Try Cured Today They're Colorado-based organically grown hemp products that have been engineered to transform your approach toward an elevated life. Tap into your inherent potential – your greatest mind-body alignment – and nourish it with the supplements you were designed to thrive on. A greater existence is waiting.   More Top Episodes 226 Paul Chek: The Revolution Is Coming (3 Part Series) 131 Drew Manning: Emotional Fitness 129 Gretchen Rubin: The Four Tendencies  183 Dr. Kyra Bobinet: Brain Science 196 Aubrey Marcus: Own The Day 103 Robb Wolf: Wired To Eat Best of The Best: The Top 10 Guests From over 200 Shows Get More Wellness In Your Life (for free) Join the Wellness Force Community on Facebook Get the M21 Calm Mind + Immunity Boosting Guide

In this episode Dr Elizabeth Lovegrove talks about research into ACE inhibitors and ARBs and the risk they pose in pregnancy. Pregnancy protection and pregnancies in women prescribed ACE inhibitors or ARBs: a cross-sectional study in primary care Read the paper: https://doi.org/10.3399/bjgp20X712997 (https://doi.org/10.3399/bjgp20X712997) Exposure to angiotensin-converting enzyme inhibitors or angiotensin receptor blockers during pregnancy is associated with teratogenic risk to the fetus. This study shows that the recording of pre-pregnancy advice and contraception in women of childbearing age, who are prescribed such medicines, is suboptimal and a number of pregnancies occur in this population. As this may place women and their babies at risk of exposure to teratogens, there is a need for significant improvements in the care of these patients.

The Filtrate:Matt SparksJoel TopfSwapnil HiremathJennie LinJordy CohenAnd two special guests:Morgan Grams, study author.Talar Kharadjian, nephrology fellow UC San DiegoShow Notes:History of albuminuria from Matt’s opening monolog: https://academic.oup.com/ndt/article/18/7/1281/1809803Microalbuminuria As A Predictor Of Clinical Nephropathy In Insulin-Dependent Diabetes Mellitus in the Lancet 1982.Microalbuminuria Predicts Clinical Proteinuria and Early Mortality in Maturity-Onset Diabetes in the NEJM 1984Episode of Freely Filtered with Dr. Feldman, the big guy at the top of the CRIC trial: NSAIDs vs Opioids.The Aldo study where they didn’t do a meta-analysis but they should have: Aldosteronism is everywhere.Estimating Urine Albumin-to-Creatinine Ratio from Protein-to-Creatinine Ratio: Development of Equations using Same-Day Measurements. Canadian data. CJASNThe kidney failure risk equation has a dotcom: https://kidneyfailurerisk.comKDIGO Controversies Conference on Early Identification & Intervention in CKDChoose Your Own Adventure: Cave of Time.Witte et al. in 2009 JASN on first morning urine vs 24 hour collection: First Morning Voids Are More Reliable Than Spot Urine Samples to Assess MicroalbuminuriaSensitivity and specificity for Joel to studyYour Manuscript On Peer ReviewNephrology Business Leaders University (NBLU)Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach with lead author Catherine Clasehttps://www.clothmasks.caElimination or Prolongation of ACE Inhibitors and ARB in Coronavirus Disease 2019 (REPLACECOVID)Fast Grant. Apparently they are not just for Brian ByrdNephJC ACE2 Stuff as Jordy calls it: http://www.nephjc.com/news/covidace2The BRACE-CORONA trial a 700 person RCT of ACEi and ARB in Covid-19. No effect. Tweet stream by Swapnil.MC Hammer is a science nerd: https://cen.acs.org/education/science-communication/Hammer-time-Science-Twitter-drummers/98/i31Hammerman origin story for the MC Hammer cartoon.Bowman Society Lecture - Race & Renal Function CalculationsBasic Research Forum for Emerging Kidney Scientists: A Partnership Between APS and ASN

Should patients with hypertension who are hospitalized due to COVID-19 continue to take angiotensin-converting enzyme inhibitors and angiotensin receptor blockers? Find out about this and more in today’s PV Roundup podcast.

Drs. Ron Waksman and Renato Lopes discuss the results of the BRACE CORONA study, which was presented as a late-breaking trial at the European Society of Cardiology virtual congress. The study examined the difference between continuing or suspending ACE inhibitors and angiotensin receptor blockers in COVID-19 patients. Dr. Lopes provides insights into the top-line findings, which is that there were no significant differences between the two treatment regimens. Watch the interview on CRTonline

Ace inhibitors, angiotensin receptor blockers, lisinopril, losartan Cardiac Pharmacology, Antihypertensive drugs, blood pressure medications, heart failure pharmacology, HF drugs, CHF drugs, hypertensive drugs, high blood pressure drugs, benazepril (Lotensin, Lotensin Hct), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc) perindopril (Aceon), quinapril (Accupril), Potassium wasting, azilsartan (Edarbi) candesartan (Atacand) eprosartan (Teveten) irbesartan (Avapro) telmisartan (Micardis) valsartan (Diovan) losartan (Cozaar) olmesartan (Benicar) Free quiz & full course at https://Simplenursing.com/nursing-school  Pharmacology Master Class - 100 videos not on YouTube - Try it for Free!    Pharmacology Master Class - Try it for Free: https://Simplenursing.com/nursing-school  100 videos not on YouTube    FREE Access to new app + 1,000 videos not on youtube!  https://Simplenursing.com/nursing-school   NCLEX FREE TRIAL:  https://simplenursing.com/NCLEX   STAY IN TOUCH

Unsere neue Folge ist online! Wir haben unseren Journal Club, Basics NIV, Basics Ernährung auf der ITS und Gerinnungsanamnese für euch vorbereitet! Ganz viel Spaß beim hören! Kommentare https://www.embryotox.de/arzneimittel/details/ondansetron/ Vermischtes Side Effects of ACE Inhibitors | Mnemonic                    CAPTOPRIL C – Cough A – Angioedema P – Potassium excess T – Taste […] Der Beitrag Podcast Mai 2020 – Folge 16 erschien zuerst auf pin-up-docs - don't panic.

Our patients are dying from a lack of oxygen-carrying capacity not a lack of respiratory capacity or lack of oxygen in the atmosphere or lack of oxygen in the respirator machine. They're dying because we're not treating the hemoglobin. - Dr. Zach Bush   Is the approach to healing COVID19 patients with respirators all wrong? Get 15% off your CURED Nutrition order with the code WELLNESSFORCE   ---> Get The Morning 21 System: A simple and powerful 21 minute system designed to give you more energy to let go of old weight and live life well.   JOIN THE FACEBOOK GROUP | *REVIEW THE PODCAST*   Wellness Force Radio Episode 345 Triple board-certified physician, Founder and CEO of ION*Biome and Executive Producer for the docu-series, Farmer's Footprint, Dr. Zach Bush, explains why COVID19 actually isn't a respiratory virus, explores humanity's awakening in the global shutdown, how spraying pesticides and insecticides has increased COVID19's impact and the use of hydroxychloroquine and cyanide poisoning kits against COVID19. Discover what tools and methods might be the key to help heal COVID19 patients efficiently and quickly.   ION*Biome ***Get 15% off of your ION*Biome order with the code JOSH1KS  ION*Gut Health supports the body’s production of beneficial enzymes through redox signaling (cellular communication). Those beneficial enzymes support the tight junctions (the seals between cells) in our gut lining – the barrier protecting us from toxic substances like glyphosate and gluten while allowing the entry of beneficial nutrients. Keeping Your Gut Healthy It’s a critical barrier to keep strong so that a vibrant microbiome can flourish. Good health depends entirely on gut health because a lot more than digestion happens in the gut. It’s also where proper immune system function begins and the majority of our neurotransmitters, such as serotonin, are created. Say yes to ION*Gut Health and you are saying yes to optimal gut-brain connectivity and feel-good transmissions, protection from the toxins we face every day in our air, water, and food, immune function, digestive wellness, and supported gluten tolerance. ***Discount code cannot be applied to subscription orders Listen To Episode 345 As Dr. Zach Bush Uncovers:   [1:30] Humanity's Awakening In The Global Shutdown Dr. Zach Bush ION*Biome 344 Leslie Manookian Dr. Ben Lynch: Dirty Genes & COVID19 Joe Rogan's great media revolution, now brought to you by Spotify CURED Nutrition Zach Bush, MD On A Pandemic Of Possibility - Rich Roll Farmer's Footprint Intrinsic Health Series M Clinic The incredible work Dr. Zach has done to further improve our connection to the earth. How Mother Nature has designed herself so that when there is an extreme event, she responds with more life and biodiversity. Exploring what the virus really is and other past coronaviruses. How big data housing sites like Amazon are now able to know when a woman is pregnant even before she knows. Big data knows you’re pregnant (and that’s not all) How humanity is having a quickening as we enter this global shutdown due to the coronavirus. Why we needed this pause as we're in this metaphorical 'womb' even if it is not gentle on us. Ramifications from debt, substance abuse, to home abuse that have increased during the lockdown of the country. How human behavior has become a virus to Mother Earth and COVID19 is allowing her to heal. Why coronaviruses aren't anything new; we've seen them before for hundreds of years.   [16:00] Why COVID19 Actually Isn't A Respiratory Virus Looking at the stats of COVID19 and the fact that patients do not have a fever, do not have a low white blood cell count and do not have any change in their respiratory rate to conclude that COVID19 is a respiratory virus. What COVID19 actually is: a toxin poisoning to the red blood cell to a small percentage of people around the world in the cities with the highest rates of air pollution. Similarities between COVID19 symptoms and someone who has had cyanide poisoning; not pneumonia. (19:00) The importance of medical staff realizing that this is not some mysterious virus they should be afraid of as variants of it have already been introduced to humans in the past. How pharmaceuticals create an imbalance and put people at risk for cardiovascular disease, kidney disease, and diabetes during this "COVID19 pandemic." (24:00) The two drugs that the AMA demands be used to treat those three diseases above: ACE Inhibitors and Statin plus the fact that ACE Inhibitors cause the main COVID19 symptom, a cough, as it sensitizes the lung. Unpacking how exactly pharmaceuticals make people more susceptible to illness as the COVID19 virus is attached to other toxic particles in the air.   [25:00] How Spraying Insecticide Has Increased COVID19's Impact How our mortality significantly went up this year due to the toxicity of the planet with all of the pollution and chemicals dumped into the environment. Why spraying insecticide and toxic chemicals all over and into the air to try to sterilize the environment has increased COVID19's impact on humans. The importance of understanding that we are killing ourselves faster by harming the environment because our natural microbiome is what prevents disease and disorders. How to get out of the way of nature and just be in harmony with it for her health and our own as she continues to serve us. The importance of understanding the second law of thermodynamics: the total entropy of an isolated system can never decrease over time, and is constant if and only if all processes are reversible. (27:00) How the second law of thermodynamics applies to depression, disease, spirituality, business, economics, politics, and more. The fact that viruses are all around us: in our land, air, and ocean plus why they are not our enemies and we would be long gone thousands of years ago if they were. (30:00) The immense economic shift as the biggest consolidation of wealth (in just a couple of hands) in human history takes advantage of the COVID19 hype and fear. Price-Pottenger The Weston A. Price Foundation 321 Sally Fallon Morell & Hilda Labrada Gore   [31:00] Use of Hydroxychloroquine And Cyanide Poisoning Kits Against COVID19 Unpacking the fact that Wuhan has the most damaged ecosystem on the planet with all of the glyphosate being sprayed and has the biggest production of chemical raised pork thus this toxic stew of their microbiome is sending out an important genomic update to the rest of the world. Similarities between SARS and COVID19 symptoms including the approach to stopping them. What a hypoxic injury is as cyanide and other toxins enter red blood cells thus making the use of a respirator useless. (33:00) Unpacking why COVID19 patients are not dying from a lack of respiratory capacity, lack of oxygen in the atmosphere, or lack of oxygen in the respirator machine but from their lack of oxygen-carrying capacity. The importance of treating a COVID19 patient's hemoglobin; not the respiratory system because this is about healing a blood toxin; not a respiratory virus. How hydroxychloroquine changes the shape of the red blood cell and could actually be one of the very few medicines to increase the body's capacity to carry oxygen. The powerful impact that could happen to treat COVID19 in minutes when we use a simple cyanide poisoning kit that every hospital has vs having patients weeks on a respirator that might not even help them. (35:00)   [41:00] The Man-Made Environmental Devastation Created On Farms How Mother Earth is doing throughout all of this as she tries to breathe through her soils and oceans. The devastation that our planet has gone through including the impact of Roundup being sprayed everywhere. Soil Health Academy Dr. Allen Williams This is Your Brain on "Food Chemistry" How overplowing a field kills the mycelia or life beneath the topsoil thus causing it to lose important nutrients. Why we'll continue to see more coronaviruses impacting humanity as our air quality continues to suffer from CO2, methane, PM2.5, and other greenhouse gases. (47:50) The fact that PM2.5 is the least of our concerns if we realize that the oceans continue to take more and more CO2 and acidify which would wipe out 85% to 97% of life on earth. How we've gotten to the point of being in the midst of the planet's 6th extinction as we've already wiped out 50% of our biology and accelerating. The incredible new life that will be born on this planet when we really start to care about the planet and stop our harmful behavior. Unpacking the grand misperception that America is feeding the world when it's really just 30% as we continue to spray out chemicals onto all of our crops that have adopted mega farming. The reality that 70% of 7 billion people on earth are fed by traditional farming practices in poor countries with small amounts of farmland as farmers are abused by economic rules and lose out to the big corporation competition. How to directly help farmers in your community by buying CSA labeled foods.   [59:00] ION*Biome & The Gut-Brain Access His product, ION*Biome, and how it helps to improve our gut-brain access for great physical, emotional, and mental health. Exploring what REDOX science is: Reduction and Oxidation and its impacts on our health. His past and current research on cancer, healing the body, and how he came to create ION*Biome. Unpacking how our exosomes of genetic information from our genome could change behavior just like a virus of other cells. Breaking down our genetic DNA and RNA in relation to bacteria and fungi in our environment plus the food we just ate that's updating our genome. The fact that we have microbiome all throughout our bodies and even in the brain. Our natural biological methodologies for cellular communication across life forms at a deeper level. Exploring time, space, and this continuous vibration of the electromagnetic field that connects all of us. How we manifest events around us as the body absorbs and sends out intentions or information to the universe.   [1:16:00] Connecting The Head & The Heart Organizing our priorities to be able to be there for the people in our lives that mean the most to us. Why there is an opportunity to grow and be more when we feel disappointed that we aren't able to be present for others. How we get so caught up in life that we forget to pause and give gratitude for everything we experience and are as humans. The true calling of physicians and health care workers plus his personal message for them. Exploring the intelligence of the physical and spiritual worlds in our universe. Why a microscopic boundary is the beginning of self-identity and healthy macro boundaries: spiritual and emotional. How to let go and surrender by stop holding onto everything you believe from the roles you have played to the identities you've taken on. Patrick Gentempo The deep spiritual conversation he was gifted to have with Patrick Gentempo. Unpacking Patrick Gentempo's message: Humanity is dying largely because we keep thinking that the fabric of life is love; the fabric of the universe we live in is beauty. Love is not a thing, action, or result; love is the experience of witnessing beauty. Why we can't manifest love; all we can do is see the beauty and react to that. Through that, we will be a vessel of love. Explaining why you don't lack self-love; you just haven't given yourself the breath and time to find your own beauty. Jenn Perell Bush M21 Wellness Guide Wellness Force Community Power Quotes From The Show How To Improve A COVID19 Patient's Oxygen-Carrying Capacity   "It turns out that the main thing hydroxychloroquine does is change the shape of the red blood cell. Malaria is a parasite that attacks the red blood cell and so hydroxychloroquine, as it turns out, is one of the few medications someone could reach for to help improve the oxygen-carrying capacity of the blood. Now there's a much more efficient approach called a cyanide poisoning kit that takes just three quick injections to change the shape of the hemoglobin into methemoglobin and it does fine. We can treat a COVID19 patient with a simple cyanide poisoning kit that every hospital has in a matter of minutes rather than weeks on a respirator where the patient is dying from pneumonia." - Dr. Zach Bush   Becoming A Vessel Of Love "We don't have to manifest love; in fact, we cannot manifest love. All we can do is see beauty and react to that. Through that, we will be a vessel of love and we will pour love through ourselves not because we know how to love but because we can recognize beauty. So, for everyone trying to struggle with why you don't have self-love, it's not because you don't love yourself, it's because you just haven't given yourself the breath and the time to find your own beauty. So, find that beauty, dig in, and you're going to be able to love like you've never known before." - Dr. Zach Bush     The Toxicity Of Our Chemical Fears, Response, & Behavior "We're seeing a lot of people dying from heart disease, cancer, and autoimmune conditions right now. Our mortality went up this year significantly because of the toxicity of the planet. We've never dumped more chemicals than we have in the last year and I don't think it's surprising necessarily that the US is seeing some of the highest mortality right now because as soon as we thought this was a virus killing us, we went and sprayed insecticide and toxic chemicals into the air all over South Korea and China. All of those toxins then went airborne and ended up in cities like Seattle and New York a couple of weeks later. That band of air that is traveling across the globe all the time is carrying the toxicity of our chemical fear and response to a toxin that was developed from our chemical behavior of transportation and energy sectors." - Dr. Zach Bush     Our Constant War With Nature "In our constant belief that we are at war with nature and all of the germs, we are killing ourselves ever faster and it is ludicrous and sad because we have twenty, thirty years of data on the microbiome to know that it's the microbiome that prevents cancer, autoimmune disease, depression, anxiety, sleep disorders, and infertility; it's all the microbiome. Yet somehow, from this ridiculous fear story, suddenly the whole world including scientists are okay with killing every organism on earth. COVID19 is just a very sad, low-vibration event." - Dr. Zach Bush   Links From Today's Show  CURED Nutrition ION*Biome 344 Leslie Manookian Dr. Ben Lynch: Dirty Genes & COVID19 Zach Bush, MD On A Pandemic Of Possibility - Rich Roll Joe Rogan's great media revolution, now brought to you by Spotify Farmer's Footprint Intrinsic Health Series M Clinic Leave Wellness Force a review on iTunes Big data knows you’re pregnant (and that’s not all) Price-Pottenger The Weston A. Price Foundation 321 Sally Fallon Morell & Hilda Labrada Gore Soil Health Academy Dr. Allen Williams This is Your Brain on "Food Chemistry" Patrick Gentempo Jenn Perell Bush M21 Wellness Guide Wellness Force Community Dr. Zach Bush Facebook Twitter Instagram YouTube   About Dr. Zach Bush Dr. Zach Bush is a physician specializing in internal medicine, endocrinology, and hospice care. He is an internationally recognized educator and thought leader on the microbiome as it relates to health, disease, and food systems.     CURED Nutrition Get 15% off your CURED Nutrition order with the code WELLNESSFORCE It's taken me over a year to find the right hemp and CBD company to introduce to the Wellness Force Community and I could not be more thrilled that it's CURED Nutrition! CURED Nutrition is a movement inspired by nature and grounded in a shared desire to leave a lasting impression on you, our community, and this world. Together, they're a collective of heart-centered human beings who are inviting you – the conscious creatives, dreamers, and healers – to join their family. Learn how CURED hemp and CBD products can enhance your daily wellness routine. Try Cured Today They're Colorado-based organically grown hemp products that have been engineered to transform your approach toward an elevated life. Tap into your inherent potential – your greatest mind-body alignment – and nourish it with the supplements you were designed to thrive on. A greater existence is waiting.   More Top Episodes 226 Paul Chek: The Revolution Is Coming (3 Part Series) 131 Drew Manning: Emotional Fitness 129 Gretchen Rubin: The Four Tendencies  183 Dr. Kyra Bobinet: Brain Science 196 Aubrey Marcus: Own The Day 103 Robb Wolf: Wired To Eat Best of The Best: The Top 10 Guests From over 200 Shows Get More Wellness In Your Life (for free) Join the Wellness Force Community on Facebook Get the M21 Calm Mind + Immunity Boosting Guide [spacer height="20px" id="2"]

Sign up for the free newsletter: chrismasterjohnphd.com/covid19-updates Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: chrismasterjohnphd.com/coronavirus DISCLAIMER: I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have a PhD in Nutritional Sciences and my expertise is in conducting and interpreting research related to my field. Please consult your physician before doing anything for prevention or treatment of COVID-19, and please seek the help of a physician immediately if you believe you may have COVID-19. SUBSCRIBE This series is based on my free daily newsletter, COVID-19 Research Updates. As a result of the time it takes to produce an video or podcast from a newsletter I wrote up, there's a slight delay between when I publish the newsletter and when you watch or listen to this. When you subscribe to the newsletter, you get the latest of my research every single day as soon as it's ready to come out. You get references and links to the sources for all the information, and you immediately get an archive of all the past issues. You can sign up at chrismasterjohnphd.com/covid19-updates SUPPORT It would mean the world to me if you support this service by purchasing a copy of my ebook, The Food and Supplement Guide to the Coronavirus. The guide contains my most up-to-date conclusions about what we should be doing for nutritional and herbal support on top of hygiene and social distancing for added protection. Due to the absence of randomized controlled trials testing nutritional or herbal prevention, these are my best guesses for what is likely to work without significant risk of harm, based on the existing science. Many people have asked why I am charging for this instead of giving it away for free, given that this is a time of crisis and people are in need. Unfortunately, I have not been immune to the effects this virus has had on the economy. My revenue from my other offerings started falling in February, and by mid-March I had days where my revenue was zero. I have three people who work for me full-time, and I am doing everything I can to avoid laying any of them off. By mid-March I had depleted 75% of my emergency fund in order to avoid any layoffs, and without charging for the guide I would not have been able to hold out much longer. Charging for the guide has allowed me to keep everyone working, replete some of my savings, and devote myself to researching COVID-19 full-time. As a result I now publish this daily COVID-19 series and the free newsletter, am involved in the design of several clinical trials that are in the process of being submitted for registration now, and am able to continually update the guide for free whenever my research warrants it. By purchasing the guide, you are enabling me to continue devoting my skills to the most important issue we now face. I am genuinely grateful for your contribution. You can purchase a copy at chrismasterjohnphd.com/coronavirus PLEASE NOTE: As a result of the COVID-19 crisis and the time I am committing to staying on top of relevant research, as well as the high volume of questions I receive, it may take me extra time to respond to questions here. For an up-to-date list of where I respond to questions most quickly, please see the contact page on chrismasterjohnphd.com.

Recorded May 2, 2020.Dr. O’Connell is joined again by Dr. Tim Horita to discuss the current state of medications including the highly publicized Hydroxychloroquine as well as other therapies including convalescent plasma.Questions from this episode include:I’d like to pick up where we left off and talk about antibody testing. There are a few terms that I want to make sure everyone understands. Can you explain the idea of seroprevalence and confirmed cases?The World Health Organization, or WHO, recently said that having COVID-19 may not prevent a second infection? Can you explain this for us?There has also been a lot of research on hydroxychloroquine as a medication to potentially prevent getting COVID-19 and also for treating more severe cases, and this includes a larger U.S. VA Hospital Study. Can you take us through what we currently know about hydroxychloroquine?Your host is Dr. Ted O’Connell, family physician, educator, and author of numerous textbooks and peer-reviewed articles. He holds academic appointments at UCSF, UC Davis, and Drexel University's medical schools and also founded the Kaiser Permanente Napa-Solano Community Medicine and Global Health Fellowship, the first program in the U.S. to formally combine both community medicine and global health. Follow Ted on Instagram (@tedoconnellmd) and Twitter (@tedoconnell)! Dr. Horita has been a practicing Family physician in Southern California for 23 years. He graduated with honors from Dartmouth Medical School in 1997. After serving as Chief Resident at the Kaiser Woodland Hills Family Medicine Residency, he became a member of their faculty, and later became program director. He continues to enjoy teaching medical students and residents, and is an Assistant Clinical Professor at the David Geffen School of Medicine at UCLA.Currently, Dr. Horita practices in Oxnard, California with the Southern California Permanente Medical Group, and in his community with the Westminster Free Clinic. His publications include several textbooks and a peer reviewed article in the journal American Family Physician.He is a member of the Alpha Omega Alpha Medical Honor Society, and in 2018 was awarded Fellow of the American Academy of Family Physicians.Links for This Episode:https://www.fightwithice.com/Submit Your Questions for the PodcastSend an email to info@arslonga.media or check out covidpodcast.comWhat Can You Do? You can help spread commonsense about COVID-19 by supporting this podcast. Hit subscribe, leave a positive review, and share it with your friends especially on social media. We can each do our part to ensure that scientifically accurate information about the pandemic spreads faster than rumors or fears. Remember to be vigilant, but remain calm. For the most trusted and real time information on COVID-19 and the coronavirus pandemic, both the CDC and WHO have dedicated web pages to keep the public informed. The information presented in this podcast is intended for educational purposes only and should not be construed as medical advice. Producers: Madison Linden and Christopher Breitigan. Executive Producer: Patrick C. Beeman, MD

How should we conduct remote consultations for suspected COVID-19? Find out about this and more in today’s PV Roundup podcast.

ACE inhibitors (angiotensin converting enzyme inhibitors) have been mentioned frequently in this series over the last month. This piece sees the long promised focus on ACE and the effects of estrogen as a way of dealing with some of the potentially fatal symptoms caused by COVID 19. It's still early days in the battle against this terrible virus, this piece presents some speculation as to where the conflict may head to. TopMedTalk provides evidence based discussions, here we ask how more evidence can be gathered as tantalizing theories emerge about dealing more effectively with these patients. Presented by Desiree Chappell with Monty Mythen and additional questions from Mike Grocott, alongside their guest Hugh Montgomery, Intensive Care Society Board Member and, Professor of Cardiovascular Genetics and Critical Care University College London. Thank you to our sponsor Edwards Lifesciences. Edwards clinical education (ECE): https://www.edwards.com/clinicaleducation

Listen to CMHC's Senior Planning Committee Member, Dr. Keith C. Ferdinand, Professor of Medicine at the Tulane University School of Medicine in New Orleans, LA, discuss whether ACEis and ARBs should be withdrawn in patients with COVID-19.

How coronavirus kills “healthy” people, with Cate Shanahan, M.D.    Check out my bestselling book, The Carnivore Code:  www.thecarnivorecodebook.com   You can find Dr Cate Shanahan and her new book at www.DrCate.com and www.FatBurnFix.com Dr. Cate Shanahan is a board certified Family Physician. Her expertise is diet-driven disease, specifically the twin roles of PUFAs and sugar in promoting weight gain, insulin resistance, prediabetes and other common diet-driven conditions. Her passion is educational programs that improve productivity & reduce employer healthcare costs by cultivating healthy habits at the individual and organization-wide levels.   After getting her BS in biology from Rutgers University, she trained in biochemistry and genetics at Cornell University’s graduate school before attending Robert Wood Johnson Medical School. She practiced in Hawaii for ten years where she studied ethnobotany and her healthiest patient’s culinary habits. She applied her learning and experiences in all these scientific fields to write Deep Nutrition: Why Your Genes Need Traditional Food. Together with Dr. Tim DiFrancesco and NBA legend Gary Vitti, she created the PRO Nutrition program for the LA Lakers and  helped forge a partnership between Whole Foods Market and numerous NBA teams. In May of 2018 she begin  Director of Metabolic Health for ABC Fine Wine and Spirits, a progressive, family run company interested in saving money by betterment of health.   Time Stamps: 10:24 How do we move forward with the Coronavirus crisis 14:29 Update on Coronavirus numbers. 15:44 What is a Coronavirus and how does it affect us? 18:54 How can ACE Inhibitors and Angiotensin receptor blockers affect those with Covid19? 25:23 Would Stephen recommend taking these medications? 30:03 Are healthy people at risk for this virus? 34:29 How do we define healthy? 38:39 Data on comorbidities and other studies. 46:37 Acute hyperglycemia and insulin resistance’s effect on the immune system. 51:51 Blood glucose levels? 56:59 Immune dysfunction in patients with Diabetes Melitus 57:54 The immune response in people with Diabetes. 1:01:51 Insulin receptor mediated stimulation and T cells. 1:03:39 Does insulin resistance impede our ability to fight a virus? 1:05:29 studies (continued) 1:07:19 Pop Sugar article on obesity. 1:09:03 The role of cholesterol in the immune system/role of fatty acid in defending against viruses 1:18:03 Statins and the immune system 1:32:13 Where to find Stephen’s work? 1:32:49 What is the most radical thing Stephen has done recently? Study mentioned: https://www.sciencedirect.com/science/article/a BluBlox: www.blubox.com use the code CarnivoreMD for 15% off your order   Ancestral Supplements https://ancestralsupplements.com/ Code SALADINOMD on the shopify site to receive 10% off.   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com

Id be happy to send you links to any of the articles talked about in this podcast but I cover the new test on the corona virus that claims to be great but the devil in the details as well as talk about more hear-say medicine and the ever popular ACE inhibitor debate

The Carnivore Code has arrived and it’s already a bestseller!! Get it here: www.thecarnivorecodebook.com   Stephen attained both his Doctorate of Chiropractic and Masters in Human Nutrition and Functional Medicine from the University of Western States in Portland, OR. He is a health coach, speaker, and the author of two books on health; The Health Evolution: Why Understanding Evolution is the Key to Vibrant Health and The Heart: Our Most Medically Misunderstood Organ. Dr. Hussey guides clients from around the world back to health by using the latest research and health attaining strategies. In his down time he likes to be outdoors, playing sports, reading, writing, and spending time with his wife and their pets.   Time Stamps: 10:24 How do we move forward with the Coronavirus crisis?14:29 Update on Coronavirus numbers.15:44 What is a Coronavirus and how does it affect us?18:54 How can ACE Inhibitors and Angiotensin receptor blockers affect those with Covid19?25:23 Would Stephen recommend taking these medications?30:03 Are healthy people at risk for this virus?34:29 How do we define healthy?38:39 Data on comorbidities and other studies. 46:37 Acute hyperglycemia and insulin resistance’s effect on the immune system.51:51 Blood glucose levels?56:59 Immune dysfunction in patients with Diabetes Melitus 57:54 The immune response in people with Diabetes.1:01:51 Insulin receptor mediated stimulation and T cells.1:03:39 Does insulin resistance impede our ability to fight a virus?1:05:29 studies (continued) 1:07:19 Pop Sugar article on obesity.1:09:03 The role of cholesterol in the immune system/role of fatty acid in defending against viruses 1:18:03 Statins and the immune system 1:32:13 Where to find Stephen’s work?1:32:49 What is the most radical thing Stephen has done recently? BluBlox: www.blubox.com use the code CarnivoreMD for 15% off your order   Ancestral Supplements https://ancestralsupplements.com/ Code SALADINOMD on the shopify site to receive 10% off.   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com

In this episode (recorded March 22, 2020), Dr. Ted O’Connell speaks with Dr. Sanaz Majd about important topics related to the COVID-19 pandemic such as:- What CFR is and how it is broken down.- The effects of ACE-inhibitors and ARBs on those who contract COVID-19.- What experts and medical societies are saying about ACE-inhibitors and ARBs.Furthermore, Dr. Majd discusses the various ways in which she is involved in medical education and provides a number of resources for medical students. Dr. Sanaz Majd is a board certified family physician in San Diego, California, and creator of her own popular YouTube channel. Dr. Majd received her undergraduate degree from the University of California San Diego and her medical degree from the Drexel University College of Medicine in Philadelphia. Dr. Majd is a medical writer and former host of The House Call Doctor podcast for a total of 9 years. To learn more about Dr. Majd, check her out on Twitter (@SMajdMD), Instagram (@smajdmd), Facebook, and TikTok! Your host is Dr. Ted O’Connell, family physician, educator, and author of numerous textbooks and peer-reviewed articles. He holds academic appointments at UCSF, UC Davis, and Drexel University's medical schools and also founded the Kaiser Permanente Napa-Solano Community Medicine and Global Health Fellowship, the first program in the U.S. to formally combine both community medicine and global health. Follow Ted on Instagram (@tedoconnellmd) and Twitter (@tedoconnell)! Submit Your Questions for the PodcastSend an email to info@arslonga.media or check out covidpodcast.comWhat Can You Do? You can help spread commonsense about COVID-19 by supporting this podcast. Hit subscribe, leave a positive review, and share it with your friends especially on social media. We can each do our part to ensure that scientifically accurate information about the pandemic spreads faster than rumors or fears. Remember to be vigilant, but remain calm. For the most trusted and real time information on COVID-19 and the coronavirus pandemic, both the CDC and WHO have dedicated web pages to keep the public informed. The information presented in this podcast is intended for educational purposes only and should not be construed as medical advice. Producers: Madison Linden and Christopher Breitigan.Executive Producer: Patrick C. Beeman, MD

SUPER short one today about COVID and ACE inhibitors (-pril) and Angiotenstin Receptors Antagonists, like Angio Recept Antag. Maybe ang rec ant. Or artan. Artans yeah, that’s it.

In this episode, Dr. O’Connell addresses misinformation regarding medications and their affects and interactions with the COVID-19 virus. Several agencies, including the FDA, have issued statements that they have found no evidence linking NSAID use and the worsening COVID-19 symptoms. There is also little scientific evidence that ACE inhibitors or ARB’s increase the risk for COVID-19 infection. The major medical societies in the United States and Europe recommend the continued use of ACE inhibitors and ARB’s even in the setting of COVID-19 infection.Special thanks to Pranay Bonagiri for helping research the topics discussed in todays episode.Your host is Dr. Ted O’Connell, family physician, educator, and author of numerous textbooks and peer-reviewed articles. He holds academic appointments at UCSF, UC Davis, and Drexel University's medical schools and also founded the Kaiser Permanente Napa-Solano Community Medicine and Global Health Fellowship, the first program in the U.S. to formally combine both community medicine and global health. Follow Ted on Instagram (@tedoconnellmd) and Twitter (@tedoconnell)! Submit Your Questions for the PodcastSend an email to info@arslonga.media or check out covidpodcast.comWhat Can You Do? You can help spread commonsense about COVID-19 by supporting this podcast. Hit subscribe, leave a positive review, and share it with your friends especially on social media. We can each do our part to ensure that scientifically accurate information about the pandemic spreads faster than rumors or fears. Remember to be vigilant, but remain calm. For the most trusted and real time information on COVID-19 and the coronavirus pandemic, both the CDC and WHO have dedicated web pages to keep the public informed. The information presented in this podcast is intended for educational purposes only and should not be construed as medical advice. Producers: Madison Linden and Christopher Breitigan. Executive Producer: Patrick C. Beeman, MD

Diagnostic testing, NSAIDs, ACE Inhibitors, antivirals, and more. Anthony Fauci, MD from NIAID discusses latest developments in the spread and clinical management of COVID-19 and the SARS-CoV-2 virus with JAMA Editor Howard Bauchner, MD. JAMA Coronavirus Resource Center

Diagnostic testing, NSAIDs, ACE Inhibitors, antivirals, and more. Anthony Fauci, MD from NIAID discusses latest developments in the spread and clinical management of COVID-19 and the SARS-CoV-2 virus with JAMA Editor Howard Bauchner, MD. JAMA Coronavirus Resource Center

The Carnivore Code has arrived and it’s already a bestseller!! Get it here: www.thecarnivorecodebook.com   There’s been so much happening so rapidly recently that I wanted to do a detailed episode about Coronavirus after really digging into the research. As we are able to create more in depth show notes we will post them at carnivoremd.com/coronavirus.  Time Stamps: 4:55 Shifting the focus away from hysteria and fear. 9;25 What is a coronavirus? 12:00 What is a virus? 13:30 Lifecycle of the Coronavirus (SARS2) 16:40 Binding/docking of proteins of coronavirus. 18:00 What is the ACE2 receptor? Why is this important in relation to hypertension? 24:20 What are the symptoms of COVID19? 26:40 What we can learn from Japan’s response to COVID19? 31:15 How the virus is transmitted. 37:00 Comparison of fatality rate to the Ro 40:10 Who is at most risk of suffering from COVID19? 44:05 How many people will get the virus? 47:30 Paul clarifying statements made on Coronavirus. 52:20 How the virus will impact our healthcare system. 56:42 Flattening the curve. 58:20 Testing for Coronavirus. 1:02:00 Incubation period. 1:03:55 Where did COVID19 come from? 1:06:00 Tracking the virus. 1:11:30 NSAiDS and SARS COV2. 1:14:21 ACE Inhibitors. 1:17:11 Who is most affected by this virus? 1:38:46 How to avoid insulin resistance. 1:42:11 Nutrient adequacy and the immune system. 1:53:46 Nutritional adequacy matters/summary.   Belcampo: Use the code CARNIVOREMD for 20% off your order!    Ancestral Supplements https://ancestralsupplements.com/ Code SALADINOMD on the shopify site to receive 10% off.   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com

In this episode, we have two guests on the show, Jared Hovatter and Madison Eichstadt. Jared is a bodybuilder who owns 2 gyms, The Flex Fitness in Morgantown, WV and 3 Guys Fitness in Masontown, WV. Madison is a nationally competitive powerlifter. She is currently in school to become a primary care physician. Topics: Who Madison is and what she's currently doing On Jared's bodybuilding competition On Madison's training Her thoughts on women who are afraid of lifting heavy weights Her favourite lift Type of water cut program she follows Why she wants to be a physician Her thoughts on birth control for women Her toughest lift Which class she typically competes in Her thoughts on women using steroids Jared's thoughts on men forcing their women to take steroids ACE Inhibitors vs. ARBs What Norvasc is and it's side effects Cardio exercise Jared likes to do before a competition Jared's thoughts on using growth hormone to get lean Why you need to monitor your body when taking steroids What Madison does to help keep an eye on her health How training affects women during their cycle On estrogen and progesterone How Jared set up his gym On having a doctor who's willing to understand and help Links: Madison on Instagram Jared on Instagram Flex Fitness website Flex Fitness on Facebook Flex Fitness on Instagram 3 Guys Fitness website 3 Guys Fitness on Facebook 3 Guys Fitness on Instagram

In this episode I cover hyperkalaemia.If you want to follow along with written notes on hyperkalaemia go to https://zerotofinals.com/medicine/renal/hyperkalaemia/ or the renal section in the Zero to Finals medicine book.This episode covers pathophysiology, causes, investigation and management of hyperkalaemia. The audio in the episode was expertly edited by Harry Watchman.

How a Brazilian scientist's knowledge of viper venom led to the discovery of a whole class of medication for high blood pressure. With Mike Freemantle.

This episode cover the cardiac medication ACE inhibitors. It includes: Mechanism of action Treatment Side effects Drug interactions Nursing considerations Patient education Contraindications It is a short, easy to understand study guide that covers the information nurses need to know. 

Today, I want to talk about a specific topic, that I've seen about 5 times total in my career: Ace inhibitor induced angioedema The first question we should ask is, why do we care (aside from it being fatal)? Well, many patient's have hypertension, and many of them are placed on an ACE inhibitor. This makes ACE inhibitors the number one cause of drug induced angioedema in the United States. The most important thing to remember is the pathophysiology.  Today, we'll do a quick review of... The pathophysiology behind why this occurs Why steroids and antihistamines will NOT help in this situation How our patient will present How long after an ACE is started will angioedema present? Diagnosing ACE induced angioedema Treating and managing your patient - Follow us on Instagram here: https://www.instagram.com/medgeeksinc - Check out our course material here: https://learn.medgeeks.co - This podcast should not be used in any legal capacity whatsoever, including but not limited to establishing standard of care in a legal sense or as a basis for expert witness testimony. No guarantee is given regarding the accuracy of any statements or opinions made on the podcast, video, or blog.

This podcast reviews the pharmaceutical class ACE inhibitors. The therapeutic class is antihypertensives. Discussion of this medication and memory helps to remember this medication are included. 

In addition to the three main classes of anti-hypertensives we already discussed, ACE Inhibitors like Lisinopril and Captopril, Beta Blockers like Metoprolol and Propranolol, and Calcium Channel Blockers like Nicardipine and Diltiazem, there are a number of other classes of… The post Cardiac Labs and Meds for Nurses appeared first on NURSING.com.

The January 2018 Archimedes podcast contains all sorts of fun looking at the safety of ACE-inhibitors in children - http://adc.bmj.com/content/103/1/106.1, squaring up to the Rule of Three (malaria tests in this instance) - http://adc.bmj.com/content/103/1/1.1 - and we also talk validation and revalidation in an attempt to predict the future http://adc.bmj.com/content/103/1/106.2. The ADC Archimedes podcast, home of the best evidence-paediatrics chat, is presented by Bob Phillips, the Social Media and Archimedes Editor. http://adc.bmj.com/content/103/1#Archimedes

Checking glucose levels in Type 2 Diabetes, ACE Inhibitors for women, and using Azithromycin in Asthma.

Prompted by the recent CAMEO trial publication on icatibant, we dive into angioedema with a focus on airway management. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Episode_107_0_Final_Cut.m4a Download Leave a Comment Tags: ACE Inhibitors, Allergy/Immunology, Angioedema, Icatibant Show Notes Take Home Points Airway management is paramount, expect a challenging intubation and consider controlling the airway early When controlling the airway, consider an awake approach and fiberoptics if available. Always be prepared for the can't intubate, can't oxygenate scenario with a double set up. If the patient has urticaria and pruritus, the process is likely histamine mediated and will respond to typical anaphylaxis treatment Finally, observe the patient for progression of swelling and don't forget to stop the inciting medication Read More Core EM: Angioedema EMCrit: Podcast 145 – Awake Intubation Lecture from SMACC ERCast: Angioedema

Prompted by the recent CAMEO trial publication on icatibant, we dive into angioedema with a focus on airway management. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Episode_107_0_Final_Cut.m4a Download Leave a Comment Tags: ACE Inhibitors, Allergy/Immunology, Angioedema, Icatibant Show Notes Take Home Points Airway management is paramount, expect a challenging intubation and consider controlling the airway early When controlling the airway, consider an awake approach and fiberoptics if available. Always be prepared for the can’t intubate, can’t oxygenate scenario with a double set up. If the patient has urticaria and pruritus, the process is likely histamine mediated and will respond to typical anaphylaxis treatment Finally, observe the patient for progression of swelling and don’t forget to stop the inciting medication Read More Core EM: Angioedema EMCrit: Podcast 145 – Awake Intubation Lecture from SMACC ERCast: Angioedema REBEL EM:

Dr Carolyn Lam:                Welcome to Circulation On the Run, your weekly podcast summary and backstage pass to the journal and its editors. I'm Dr. Carolyn Lam, associate editor from the National Heart Center, and Duke National University of Singapore. Our feature paper this week discusses the very important patient group with myocardial infarction and non-obstructive coronary artery disease, a paper that we will be digging deep into right after these summaries.                                                 The first paper identifies a novel therapeutic target in pulmonary arterial hypertension, and that is nicotinamide phosphoribosyltransferase, a cytozyme which regulates intracellular NAD levels and cellular redox state, regulates histone deacetylases, promotes cell proliferation, and inhibits apoptosis.                                                 This is a paper from first author Dr. Chen and co-corresponding authors Dr. Machado from University of Illinois Chicago and Dr. Garcia from the University of Arizona. The authors found that plasma and mRNA and protein levels of  nicotinamide phosphoribosyltransferase  were all increased in the lungs and the isolated pulmonary arterial endothelial cells from patients with pulmonary arterial hypertension.                                                 They were also increased in the lungs of rodent models of pulmonary hypertension. Nicotinamide phosphoribosyltransferase deficient mice were protected from hypoxia mediated pulmonary hypertension; whereas, enhanced activity promoted human arterial smooth muscle cell proliferation via paracrine effect and inhibition of activity attenuated pulmonary hypertension in rats.                                                 This paper, therefore, provides evidence that nicotinamide phosphoribosyltransferase plays a role in pulmonary vascular remodeling and its inhibition could be a potential therapeutic target for pulmonary arterial hypertension.                                                 The next study suggests that high sensitivity cardiac troponin T may be an early biochemical signature for clinical and subclinical heart failure. In this study from first author Dr. Seliger, corresponding author Dr. deFilippi, and colleagues from Inova Heart and Vascular Institute, the authors measured high sensitivity cardiac troponin T at baseline among almost five thousand participants in the multi-ethnic study of atherosclerosis MESA cohort, who were initially free of overt cardiovascular disease.                                                 Cardiac magnetic resonance imaging was performed at baseline and repeated 10 years later among 2,831 participants who remain free of interim cardiovascular disease events, among whom 1,723 also received gadolinium enhanced cardiac magnetic resonance for characterization of replacement fibrosis by late gadolinium enhancement. Results showed that a mild elevation of high sensitivity cardiac troponin T identified subjects at highest risk for an increase in left ventricular mass and end diastolic volume over the next 10 years.                                                 Higher levels also associated with an increased incidence of replacement fibrosis, but with no differentiation between ischemic or non-ischemic fibrosis patterns. For the more high levels remained an independent predictor for incident heart failure, coronary heart disease events and cardiovascular events, independent of underlying left ventricular hypertrophy or ejection faction.                                                 The implications are that myocyte injury, measured with a highly sensitive cardiac specific troponin assay may ultimately be an important early signal used to target therapy to prevent or delay left ventricular remodeling and progression to heart failure.                                                 Does maintenance of cardiovascular risk factors at target eliminate the excess risk of mortality in cardiovascular diseases associated with type 1 diabetes? Well, this question was addressed in the next paper by Dr. Rawshani and colleagues of the Swedish National Diabetes Register in Gothenburg Sweden. The authors compared more than 33,300 patients with type 1 diabetes to more than 166,500 match controls without diabetes from the Swedish National Diabetes Register. They found that patients with type 1 diabetes, with five selected cardiovascular risk factors at target, demonstrated a non-significant access risk of death compared to controls.                                                 These five risk factors included glycated hemoglobin, blood pressure, albuminuria, smoking, and LDL cholesterol. Nonetheless, despite having all risk factors at target, persons with type 1 diabetes still had 82% to 97% elevated risk of myocardial infarction and heart failure respectively. For every incremental risk factor not at target, the excess risk of death in cardiovascular outcomes increased in a graded fashion.                                                 In conclusion, there was a steep graded association between decreasing number of cardiovascular risk factors at target and major adverse cardiovascular outcomes with patients with type 1 diabetes. While achievement of current evidence based target levels of five cardiovascular risk factors markedly reduced or even potentially eliminated the excess mortality risk, these patients remained at higher risk of myocardial infarction and heart failure compared with controls.                                                 The final paper suggests that hemodynamic guided heart failure management may be beneficial in general clinical practice and not just in the context of controlled trials. In this study by Dr. Heywood and colleagues from Scripps Clinic Torrey Pines in La Jolla, California, the authors examined the first 2,000 patients implanted with the novel Pulmonary Artery Pressure Sensor, CardioMEMS, in the general cardiology practice setting.                                                 They found that patients uploaded information an average of every 1.2 days, and that pressures were significantly reduced by remote monitoring using the Pulmonary Artery Sensor where patients with the highest mean pulmonary artery pressures had the highest reduction in pressures. Furthermore, they found that these general use patients experienced a greater reduction in pulmonary artery pressure over time compared to those in the pivotal CHAMPION clinical trial.                                                 The results from this large observational study, therefore, demonstrates hemodynamic heart failure management may be effective in U.S. clinical practice with high rates of patient adherence and effective pressure management.                                                 This paper is accompanied by an excellent editorial by Drs. Gorter, Rienstra, and van Veldhuisen from University Medical Center, Groningen, Netherlands, which really places this paper in the clinical context of heart failure and particularly patients with heart failure and preserved ejection faction                                                 Well that wraps it up for your summaries. Now for our feature discussion.                                                 We're discussing a hugely important emerging issue today. And it's MINOCA, a myocardial infarction with non-obstructive coronary arteries, and a very important paper in today's issue, which really provides the first insight into potential long-term medical therapy in the management of MINOCA.                                                 However, now this issue of MINOCA is quite new and I'm sure new to many of those listening on the line. So, I am with the first and corresponding author of the paper, Dr. Bertil Lindahl from Uppsala Clinical Research Center in Sweden. Welcome. Dr Bertil Lindahl:               Thank You. Dr Carolyn Lam:                And also the associate editor who managed this paper, Dr. Gabriel Steg from Hospital Bichat in Paris, France. Welcome back. Dr Gabriel Steg:                Hello. Dr Carolyn Lam:                Now, we need to start by first understanding what we're talking about. MINOCA ... give us a good definition of what you mean by MINOCA. And does it include the non-coronary causes of AMI, or non-obstructive disease? Does it include myocarditis? Does it include the non-cardiac causes, like pulmonary embolism? Dr Bertil Lindahl:               Our definition of MINOCA used in this paper is that you received the ICD code for acute myocardial infarction. If you have a clinically clear case of myocarditis or Takotsubo and were not included in this analysis. But we know if we look into patients that have got the diagnosis of myocardial infarction ... if you performed, for instance, MRI afterward, you can see that a portion of the patients experience ... between 10 and 30 percent of the MINOCA patients, have evidence of myocarditis, although it was not clinically expected.                                                 So this is a heterogeneous population ... initial diagnosis was myocardial infarction. Dr Carolyn Lam:                Thank you for clarifying what you used in your study. Gabriel, could I just, you know, bring you in on this because you invited an excellent editorial that accompanies this paper. And, basically, it helps to get us past all this terminology you know, MINOCA now. Could you maybe just clarify the overall perspective of what it means? Dr Gabriel Steg:                Yeah. This area is fairly new and we still have a major nomenclature problem. Clearly it's been recognized for many years that patients who have a clinical syndrome of myocardial infarction do not necessarily have obstructive coronary artery disease. At least severe obstructive coronary artery disease. Many patients have mild lesions and some patients apparently have no lesion at all.                                                 Now, over the last few years we've understood that this is really a syndrome. And that under that big umbrella, there are patients who have non-cardiac causes of troponin elevation and chest pain. These should be excluded from MINOCA. If you have pulmonary embolism, this is not MINOCA. This is pulmonary embolism.                                                 The second aspect is there are more subtle distinctions to be made with fairly new entities such as Takotsubo. When this study was started, Takotsubo was an emerging disease concept. And so the authors were not able to properly rule out the Takotsubos and probably a few myocarditis from their data set. We now have learned over the past few years that MRI is an excellent tool to screen MINOCA patients and flush out patients who have myocarditis or Takotsubo, which are not rare. Actually it's a substantial portion of that entity.                                                 And then we're left with what I call the true MINOCA. Now what's fascinating in the study here is really that ... first of all I want to say this is another great study from our Swedish colleagues leveraging their data collection tools, which are remarkable. Really an example to the world.                                                 The second thing is they have collected ten years of data on MINOCA. And they're able to tease out which are the agents that should be using secondary prevention in that population. Elegantly demonstrating with sensitivity analysis and positive and negative controls what are the agents associated with improved outcomes and what are the agents that apparently do not impact outcomes.                                                 So even though at the time they were not able to rule out myocarditis and Takotsubo properly, still the sheer size of their study, long term follow up, and the careful statistical analysis that they've done are remarkable. Dr Carolyn Lam:                I couldn't agree more. And more so in an area that is really emerging in importance. And for which we don't have any prospective clinical trials. I'm correct in saying that, right ? So Bertil, this would be a great point for you to let us know what are the main findings from your study please. Dr Bertil Lindahl:               The main findings are that statins are associated with a beneficial effect on the cardiac event. And also, ACE inhibitors or ARBs , while we were not able to show statistically things you can affect with beta blockers and similarly not with dual anti-platelet treatment. So that's basically the main findings of the study. Dr Carolyn Lam:                May I ask how have these findings personally impacted your clinical practice or do you think the next steps are gaps that need to be addressed first? Dr Bertil Lindahl:               I think that's an ongoing discussion in Sweden now and in our hospital on how this should be applied to clinical practice. Nothing. It will have an effect that statins and ACE Inhibitors or ARBs will be used. I'm not sure whether we still can say that we should not use beta blockers or dual antiplatelet treatment. But I think also that we are now discussing we should do a randomized clinical trial to really tease out whether we should use beta blockers or not or also verifying the findings regarding ACE Inhibitors and ARBs.                                                 So, I think there's always a discussion whether we can really use observation studies for treatment decision. But I think since we don't have any better trials so far I think that this is the best that we can get. So I think it will be used and applied in clinical practice. Dr Carolyn Lam:                Indeed. I really agree with what Gabriel said this is the best available evidence we have now. And my personal take home message was to pay more attention to the statins and the ACE Inhibitors. So congratulations on this great study.                                                 Gabriel, what do you think? What are next steps? I mean, MINOCA's not even in the guidelines now. Our guidelines talk about type 1, type 2, AMI ...how does it all fit in? Dr Gabriel Steg:                Well, we've seen a sea change in the concepts regarding myocardial infarction over the last fifteen years with the advent of troponin and the ability to diagnose new patients that previously we wouldn't even label as an MI.                                                 The second aspect is we've recognized over the years that there are some genuine MI's that don't have severe obstructive coronary artery disease. Now what's interesting is that some of them may have apparently mild obstructive disease. Which presumably is related to coronary dissections, embolism, plaque rupture with thrombosis that disappeared in the interim. And some of them may have actually "clean" coronary arteries and have myocardial infarction related to other mechanisms such as micro vascular mechanisms. What's interesting, and I'd like to ask the opinion of Dr. Lindahl is, these three types of diseases; mildly obstructive disease, coronary dissection, and microvascular angina are all more frequent among women. And I wonder whether you have any insights regarding gender differences in your registry. Dr Bertil Lindahl:               In this study, in the sub-group analysis we saw no significant interaction between gender and the effects. But unfortunately we don't have the registry information between , let's say completely "normal coronary arteries" versus "mildly obstructed coronary arteries". And that's a clear limitation of this study. It will be very interesting to see whether these effects are similar in these two sub-groups.                                                 It seems from other studies that approximately fifty percent of the MINOCA patients that have normal coronary arteries and fifty percent that have mild aortic disease. So this is a limitation of this study and I think that's just something we have to look for in the future. And I hope that we will have in the registry onwards, data on whether this normal or mild coronary artery disease. Dr Carolyn Lam:                Really appreciate that and really appreciate the insights you gentlemen have shared. Any final words or concluding remarks, Gabriel? Dr Gabriel Steg:                Well, again congratulations on the great study. I would refer our readers to the excellent editorial of John Beltrame that accompanies this paper, which reviews the concepts of MINOCA, the nomenclature, and some of the remaining and lingering questions that plague the field. And delineates way forward for studies.                                                 I think it's a fascinating area. I'm sure we're going to hear a lot more, both from the Swedish Heart Registry as well as other data sources. I think we all need to stay tuned to this important area. The prognosis of these patients is not so good, so we need to pay attention to that entity. Dr Carolyn Lam:                Wonderfully put. Well, thank you listeners for joining us this week. Please share this episode with all of your friends. So thank you and join us next week.  

Sure is an ace way to decrease blood pressure Quizlet

This PL Voices episode is a clip from one of our many editorial discussions. This one took place on February 17, 2016 and is led by our Editor, Sherri Boehringer, PharmD, BCPS. You’ll hear the voices of Editorial Board members Steven E. Nissen, MD, MACC, Cleveland Clinic, Ohio; and Craig D. Williams, PharmD, FNLA, BCPS, Oregon Health and Science University. You’ll also listen to cardiovascular disease expert Suzanne Oparil, MD, FACC, FAHA, FASH, FAPS, University of Alabama at Birmingham. You can read our brief, to-the-point Recommendation and dive into the evidence-based details if you wish. To learn more, visit pharmacistsletter.com.

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