Podcasts about Electromyography

Electrodiagnostic medicine technique for evaluating and recording the electrical activity produced by skeletal muscles

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Electromyography

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Best podcasts about Electromyography

Latest podcast episodes about Electromyography

Anesthesiology Journal's podcast
Featured Author Podcast: Accuracy and Precision of Train-of-four Ratio

Anesthesiology Journal's podcast

Play Episode Listen Later Jul 22, 2024 38:28


Moderator: BobbieJean Sweitzer, M.D. Participants: Andrew Bowdle, M.D., Ph.D. and Sorin J. Brull, M.D. Articles Discussed: Accuracy and Precision of Three Acceleromyographs, Three Electromyographs and a Mechanomyograph Measuring the Train-of-Four Ratio in the Absence of Neuromuscular Blocking Drugs Vital Sign Data Quality: Not Just a Retrospective Research Problem Accuracy and Precision of Acceleromyography, Electromyography and Mechanomyography: Time to Re-think What We Know Transcript

AANEM Presents Nerve and Muscle Junction
Comparison of Muscle Ultrasound and Needle Electromyography Findings in Neuromuscular Disorders

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Apr 30, 2024 16:29


Dr. Kelly Gwathmey interviews Dr. Juerd Wijntjes on The Comparison of Muscle Ultrasound and Needle Electromyography Findings in Neuromuscular Disorders.

Date Night with Barbara & Teja
Disney Daze: Steps, Rides, and Relaxation

Date Night with Barbara & Teja

Play Episode Listen Later Apr 15, 2024 32:42


Join us for our 24,000 step-per-day trip to Disney World! Teja pampered his bad leg in the mornings, while Barbara and our daughter hit the early entry lines. We go deep into the immersive Star Wars experience and speculate about the happiest dungeon in the world. With expert help from Haley at Wishing Well Travel (not sponsored), we managed to navigate the intricate dance of magic bands, dining plans, and Lightning Lanes. Tune in for our Disney episode.Traveling to Disney?Here's Wishing Well Travel: https://wishingwelltravel.com/ (not sponsored)

MedLink Neurology Podcast
BrainWaves #90 Conduction block, and why it confuses me

MedLink Neurology Podcast

Play Episode Listen Later Jan 12, 2024 20:23


MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released December 21, 2017 Nerve conduction testing should not be as puzzling as it's made out to be. This week, we break it down into individual components and use two case examples to explain how you might interpret this commonly implemented electrodiagnostic assessment. Produced by James E Siegler. Music by Coldnoise, Jessie Spillane, Loyalty Freak Music, and Yshwa. Voiceover by Erika Mejia. BrainWaves' podcasts and online content are intended for medical education only and should not be used for routine clinical decision-making. REFERENCES Allen JA. Chronic demyelinating polyneuropathies. Continuum (Minneap Minn) 2017;23(5, Peripheral Nerve and Motor Neuron Disorders):1310-31. PMID 28968364Kincaid JC. Neurophysiologic studies in the evaluation of polyneuropathy. Continuum (Minneap Minn) 2017;23(5, Peripheral Nerve and Motor Neuron Disorders):1263-75. PMID 28968361Pareyson D, Scaioli V, Laurà M. Clinical and electrophysiological aspects of Charcot-Marie-Tooth disease. Neuromolecular Med 2006;8(1-2):3-22. PMID 16775364Preston DC, Shapiro BE. Electromyography and neuromuscular disorders: clinical-electrophysiologic correlations. 3rd ed. London; New York: Elsevier Saunders, 2013.  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date. 

The Dictionary
#E47 (electrometallurgy to electronic mail)

The Dictionary

Play Episode Listen Later Nov 7, 2023 28:48


I read from electrometallurgy to electronic mail.     Electrometers have really changed over the years. https://en.wikipedia.org/wiki/Electrometer     Ooh! Electromotive force has fun formulas! https://en.wikipedia.org/wiki/Electromotive_force     You gotta check those muscles! Electromyography! https://en.wikipedia.org/wiki/Electromyography And here you can hear what it sounds like. It's very clicky. https://youtu.be/4kkIvP1jNLA?si=VaJnYs-J476eO-Uq&t=559     Our understanding of electrons is probably going to evolve greatly in the next 50 years.  https://en.wikipedia.org/wiki/Electron They are 1.602 x 10 to -19 coulombs which (I think) is 0.0000000000000000001602.     The word of the episode is "electronica". https://en.wikipedia.org/wiki/Electronica     Theme music from Jonah Kraut https://jonahkraut.bandcamp.com/     Merchandising! https://www.teepublic.com/user/spejampar     "The Dictionary - Letter A" on YouTube   "The Dictionary - Letter B" on YouTube   "The Dictionary - Letter C" on YouTube   "The Dictionary - Letter D" on YouTube   "The Dictionary - Letter E" on YouTube     Featured in a Top 10 Dictionary Podcasts list! https://blog.feedspot.com/dictionary_podcasts/     Backwards Talking on YouTube: https://www.youtube.com/playlist?list=PLmIujMwEDbgZUexyR90jaTEEVmAYcCzuq     dictionarypod@gmail.com https://www.facebook.com/thedictionarypod/ https://www.threads.net/@dictionarypod https://twitter.com/dictionarypod https://www.instagram.com/dictionarypod/ https://www.patreon.com/spejampar https://www.tiktok.com/@spejampar 917-727-5757

LiveWell Talk On...
279 - Electromyography (Dr. Devin Smith)

LiveWell Talk On...

Play Episode Listen Later Nov 1, 2023 17:46


Dr. Devin Smith, physician with St. Luke's Physical Medicine and Rehab, joins Dr. Arnold to discuss Electromyography, which is a helpful tool used to assess the health of muscles, and the nerve cells that control them.To learn more about rehabilitation services available at St. Luke's visit unitypoint.org.Do you have a question about a trending medical topic? Ask Dr. Arnold! Submit your question and it may be answered by Dr. Arnold on the podcast! Submit your questions at: https://www.unitypoint.org/cedarrapids/submit-a-question-for-the-mailbag.aspxIf you have a topic you'd like Dr. Arnold to discuss with a guest on the podcast, shoot us an email at stlukescr@unitypoint.org.

MedLink Neurology Podcast
BrainWaves #5 Foot Drop

MedLink Neurology Podcast

Play Episode Listen Later Oct 4, 2023 6:20


MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021.Originally released: July 18, 2017Quick tutorial to help you navigate through the causes of foot drop. Check it out!BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision-making in routine clinical practice. Any cases discussed in this episode are fictional and do not contain any patient health-identifying information. The content in this episode was vetted and approved by Colin Quinn for broadcast.REFERENCESPreston DC, Shapiro BE. Electromyography and Neuromuscular Disorders. 3rd ed. Saunders, 2013.We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

ASRA News
Fundamentals of Electromyography for Chronic Pain Physicians

ASRA News

Play Episode Listen Later Jul 26, 2023 13:29


"Fundamentals of Electromyography for Chronic Pain Physicians" by Dr. Eugene Maida, and Dr. Adrian Opala, both from McMaster University. From ASRA Pain Medicine News, May 2023. See original article at www.asra.com/may23news for figures and references. This material is copyrighted. 

MedStar Health DocTalk
What's an electromyography (EMG)? And why do I need one?

MedStar Health DocTalk

Play Episode Listen Later Jun 16, 2023 41:23


From a test that lasts an average of 40-minutes, patients with nerve injuries or neuro-muscular conditions can learn a lot about the health of the nerves signaling messages to muscles. The test is called an electromyography, or EMG.  Neurologist Dr. Derrick Fox of MedStar Health explains why the test is useful, who should be tested, what information is gleaned from it, how it is conducted, and more....For more episodes of MedStar Health DocTalk, go to medstarhealth.org/doctalk.

MedLink Neurology Podcast
BrainWaves #40 Teaching through clinical cases: Wrist drop

MedLink Neurology Podcast

Play Episode Listen Later Mar 14, 2023 12:36


MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: July 18, 2017 This week, I'm handing the mic over to Dr. Laura Mainardi so she can give us some pointers on the evaluation of hand weakness. We're thumbing through a few tips on working up wrist drop in particular. Hoping you give us two thumbs up on this one! ;-) BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision-making in routine clinical practice. REFERENCES Preston DC, Shapiro BE. Electromyography and Neuromuscular Disorders. 3rd ed. Saunders, 2013.  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

Born to be Barefoot | From Science to Life
Surface Electromyography with David Lemke | Understanding Proper Function and Body Movement

Born to be Barefoot | From Science to Life

Play Episode Listen Later Mar 8, 2023 77:03


Today we have the privilege of meeting and talking with David Lemke, who we could describe as a wizard in body work. He's a technical wizard using a method of technology called Surface Electromyography (SEMG), EEG, and various other things. Electromyography means muscles that are monitored and Surface means we're monitoring from the surface and not putting needles in your body and all through your motions. It's a listening device and they use wireless systems so you can move pretty much completely unimpaired while they monitor electrical activity in the muscles. They add in kinesiological surface EMG because it's, in effect, a way of studying movement and they're using that technology to study what's happening in muscles during movement. Join us as we discuss David's story and this treatment he does to improve athletes' results. Consulting work 2:38Autistic children and the need for movement and play 10:00How David wants to be described 24:09Combining the best of the new with the old 29:45Functional Chain Trainer 34:41Taking an unbalanced motor system for a run and going backwards 48:00Helping the whole body work together properly 59:47“I had a knee injury and I found that going backwards down hills was actually pain free, whereas forward up hills was pain free, but if I went forward down a hill, it would be a lot of pain. I had an anterior meniscus tear, and so I had to train to recover from that injury by going backwards down the hills.” 51:16www.davelemke.usbioperformancetx@gmail.com

MedLink Neurology Podcast
BrainWaves #158 Teaching through clinical cases: A primer on proximal weakness

MedLink Neurology Podcast

Play Episode Listen Later Feb 15, 2023 18:35


MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: March 5, 2020 Generalized weakness is a common complaint. Much of the time, we as neurologists don't even see these patients in the hospital or the clinic. But more often than not, “generalized” weakness may be the only way a patient describes difficulty brushing their hair or climbing stairs. In these situations, it's not exactly generalized weakness. It's something else. This week on BrainWaves, we review the major patterns of weakness that characterize the most common muscle disorders. With a quick review of EMG findings. Enjoy! Produced by James E Siegler. Music courtesy of Jahzzar, Kevin McLeod, Patches, and Montplaisir. Unless otherwise mentioned in the podcast, no competing financial interests exist in the content of this episode. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES Clark KE, Isenberg DA. A review of inflammatory idiopathic myopathy focusing on polymyositis. Eur J Neurol 2018;25(1):13-23. PMID 28816394 Fayssoil A, Ogna A, Chaffaut C, et al. Natural history of cardiac and respiratory involvement, prognosis and predictive factors for long-term survival in adult patients with limb girdle muscular dystrophies type 2C and 2D. PLoS One 2016;11(4):e0153095. PMID 27120200 Harris E, Bladen CL, Mayhew A, et al. The Clinical Outcome Study for dysferlinopathy: An international multicenter study. Neurol Genet 2016;2(4):e89. PMID 27602406 Preston DC and Shapiro BE. Electromyography and neuromuscular disorders: clinical-electrophysiologic correlations. 3rd ed. London; New York: Elsevier Saunders; 2013. Suresh E, Wimalaratna S. Proximal myopathy: diagnostic approach and initial management. Postgrad Med J 2013;89(1054):470-7. PMID 23596213 Walter MC, Reilich P, Thiele S, et al. Treatment of dysferlinopathy with deflazacort: a double-blind, placebo-controlled clinical trial. Orphanet J Rare Dis 2013;8:26. PMID 23406536 Wicklund MP. The limb-girdle muscular dystrophies. Continuum (Minneap Minn) 2019;25(6):1599-618. PMID 31794462 rAAVrh74.MHCK7.DYSF.DV for Treatment of Dysferlinopathies. Clinicaltrials.gov: https://www.clinicaltrials.gov/ct2/show/NCT0271050022. Accessed December 2019. For great video examples of EMG findings in nerve and muscle disease, check out KImura & Kohara's YouTube recordings: https://www.youtube.com/watch?v=6-3PP...  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date. 

PaperPlayer biorxiv neuroscience
Early rise and persistent inhibition of electromyography during failed stopping

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Jan 9, 2023


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.09.523332v1?rss=1 Authors: Fisher, M., Trinh, H., O'Neill, J., Greenhouse, I. Abstract: Reactively canceling movements is a vital feature of the motor system to ensure safety. This behavior can be studied in the laboratory using the stop signal task. There remains ambiguity about whether a point-of-no-return exists, after which a response cannot be aborted. A separate question concerns whether motor system inhibition associated with attempted stopping persists when stopping is unsuccessful. We address these two questions using electromyography (EMG) in two stop signal task experiments. Experiment 1 (n = 24) involved simple right and left index finger responses in separate task blocks. Experiment 2 (n = 28) involved a response choice between the right index and pinky fingers. To evaluate the approximate point-of-no-return, we measured EMG in responding fingers during the 100 ms preceding the stop signal and observed significantly greater EMG amplitudes during failed than successful stop trials in both experiments. Thus, EMG differentiated failed from successful stopping prior to the stop signal, regardless of whether there was a response choice. To address whether motor inhibition persists after failed stopping, we assessed EMG peak-to-offset durations and slopes (i.e., the rate of EMG decline) for go, failed stop, and successful stop (partial response EMG) trials. EMG peak-to-offset was shorter and steeper in failed stop trials compared to go and successful stop partial response EMG trials, suggesting motor inhibition persists even when failing to stop. These findings indicate EMG is sensitive to a point at which participants can no longer successfully stop an ongoing movement and suggest the peak-to-offset time of response-related EMG activity during failed stopping reflects stopping-related inhibition. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Ageless and Timeless with Michele Hughes
Michael E. Hebrard, M.D. is a board-certified Physiatrist

Ageless and Timeless with Michele Hughes

Play Episode Listen Later Nov 29, 2022 52:01


Michael E. Hebrard, M.D. is a board-certified Physiatrist specializing in physical medicine, pain management, and work injury. Dr. Hebrard has extensive experience in rehabilitation and functional medicine which aims to enhance and restore functional ability and the quality of life to those with physical impairment or disabilities affecting the brain, spinal cord, nerves, bones, joints, ligaments, muscles, and tendons. Dr. Hebrard has procedural experience in large joint and trigger point injections, Electromyography and Nerve Conduction Study (EMG), and comprehensive medical disability evaluations. Given his vast experience, Dr. Hebrard has been deposed regarding various patient cases, and has been requested to provide expert testimony related to injury, functional impairment, and appropriate future medical treatment plans. Dr. Hebrard attended the University of California, Berkeley where he earned a Bachelor of Science in Psychology with a minor in Biology; and studied medicine at The Creighton University School of Medicine in Omaha, Nebraska. Dr. Hebrard performed his internship in General Surgery, and completed his residency in Physical Medicine and Rehabilitation, both at Stanford University Medical Center. Dr. Hebrard is a California Division of Workers' Compensation Qualified Medical Evaluator, and has been in private practice for 22 years. 

This Week in Parasitism
TWiP 208: A red herring

This Week in Parasitism

Play Episode Listen Later Aug 18, 2022 64:15


The TWiP team solves the case of the Woman Who Vomited Up a Worm, and discuss how malaria transmission intensity can modify the effectiveness of the RTS, S/AS01 vaccine in Africa. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Malaria intensity modifies vaccine effectiveness (J Inf Dis) Letters read on TWiP 208 Become a patron of TWiP Case Study for TWiP 208 An adult female resident of Hawai'i presented to the emergency department (ED) with several days of fever, abdominal pain, urinary hesitancy, and generalized itchiness. white blood cell [WBC] count 14,000 cells/mL) without eosinophilia. Urinalysis suggested a urinary tract infection and she was treated for acute UTI and discharged home.  The following day she returned to the ED because of worsening abdominal pain, bilateral hip and leg pain, dizziness, diffuse hyperesthesia, and allodynia (Pain from stimuli which are not normally painful)  (worse on her feet and legs.) Urine culture from her initial ED visit grew normal urogenital flora. Her leukocytosis increased and she now had eosinophilia (WBC count 15,500 cells/mL; absolute eosinophil count 574). Laboratory evaluation was otherwise unremarkable. CT scans of the brain, abdomen, and pelvis were normal. She was hospitalized and her allodynia worsened despite treatment with analgesics. She also developed a sensation of “electric eels swimming through [her] body. Electromyography and nerve conduction studies were normal. The patient underwent a lumbar puncture and CSF examination was notable for eosinophilic meningitis with 138 WBCs and 13% eosinophils (absolute eosinophil count 18). Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees

That's Cool News | A weekly breakdown of positive Science & Tech news.
113. Neural Sleeve for Mobility Issues, Micro Teeth Cleaning Robots, Supercharger Open to Non-Teslas

That's Cool News | A weekly breakdown of positive Science & Tech news.

Play Episode Listen Later Jul 11, 2022 29:47


News: This new neural sleeve helps people overcome mobility challenges | ZDNet (01:08) A new mobility sleeve under development and out of stealth promises a compelling solution for those suffering a variety of mobility issues.Monitor and stimulate the neuromuscular system Lightweight next-gen mobility devices The technology was invented by Jeremiah Robison, a Silicon Valley serial entrepreneur, following his daughter's cerebral palsy diagnosis.Inspired by two of his daughter's clinical experiences. The first inspiration was a complex data capture session at a gait lab using optical and EMG sensors, which recorded precise information about her walk.Electromyography sensors, also known as EMG sensors, measure small electromyographic signals generated by your muscles as you move them.  The second inspiration was functional electrical stimulation as part of her physical therapy.Electrode pads were placed on individual muscle groups, which a therapist stimulated during walking sessions to stimulate and strengthen the muscles. The device & company that was created is called CIONICThe device is a wearable for people with mobility issues that doesn't just monitor leg movements but actually helps activate the person's muscles. CIONIC partnered with the Laboratory for Engineering of the Neuromuscular System (LISiN) at The Polytechnic University of Turin. Robison talked on the device:“We set out to create a product that combined the diagnostic power of a multi-million dollar gait lab with the therapeutic power of Functional Electrical Stimulation (FES) … We were confident we could leverage the recent technological advances enabling innovative products like self-driving cars and apply it to the human body to solve an enormous problem: 14% of adults in the US experience mobility impairment, a number expected to balloon to 20% by 2050."  The resulting sensor array successfully combines electromyography (EMG) and functional electrical stimulation (FES).LISiN Lab helped develop a comprehensive risk assessment strategy to ensure that the product was effective and safe Meta open sources early-stage AI translation tool that works across 200 languages | The Verge (08:37)  Social media conglomerate Meta has created a single AI model capable of translating across 200 different languagesThe company is open-sourcing the project in the hopes that others will build on its work. The AI model is part of an ambitious R&D project by Meta to create a so-called “universal speech translator,” which the company sees as important for growth across its many platforms Machine translation allows Meta to better understand its users (and so improve the advertising systems that generate 97 percent of its revenue)Could also be the foundation of a killer app for future projects like its augmented reality glasses. While most machine translation models handle only a handful of languages, Meta's model is all-encapsulating: it's a single system able to translate in more than 40,000 different directions between 200 different languages. Meta AI research scientist Angela Fan, who worked on the project, says the model, described in a research paper here, is already being tested to support a project that helps Wikipedia editors translate articles into other languages. Additionally, Fan stated that an important decision was to open-source as many elements of the project as possible — from the model to the evaluation dataset and training code. Meta also offers grants to researchers who want to contribute to such translation projects but are unable to finance their own projects We are going to end off with a quote from Fan:“I think that's really, really important, because it's not like one company will be able to holistically solve the problem of machine translation … It's everyone — globally — and so we're really interested in supporting these types of community efforts.”   Tiny shapeshifting robots brush and floss your teeth, kill bacteria | New Atlas (14:53) Engineers at the University of Pennsylvania have developed a system of microrobots that can change shape to form bristles or floss. They don't just brush plaque away, but release antimicrobials to kill bad bacteria. If you want to outsource brushing your teeth to robots. Part of the problem with teeth brushing is that toothbrushes don't account for differences in the shape or spacing of different people's teeth.The new system solves that issue by effectively shapeshifting. It's made up of iron oxide nanoparticles, which can be assembled into different formations and controlled using magnetic fields. The particles can be arranged into the shape of bristles to brush plaque from tooth surfaces, or thinner floss-like strands to scrub between teeth. Iron oxide is known to activate hydrogen peroxide, triggering a reaction that produces free radicals that kill bacteria and the sticky biofilms they form on teeth. The system was tested on a flat slab of artificial tooth-like material, then a 3D-printed tooth model, and finally on real human teeth. The tests showed that these microrobots could efficiently remove plaque and biofilms, reducing pathogenic bacteria below detectable levels. Also showed they could precisely control the bristle stiffness and length by adjusting the magnetic field.This allowed the tips to be made firm enough to clean the teeth but still soft enough to be gentle on gums. The researchers say that the customizability of this microrobot system could clean people's teeth better, while its hands-free potential could allow people with reduced fine motor skills to still take care of their oral health. New drug increases human life span by 30%, according to Mayo Clinic | Brighter Side News (19:47) Scientists may never find the elixir of life, but they are finding new ways to extend our life spans. Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that may protect older people against aspects of aging and a range of diseases. Senolytics developed at Mayo Clinic and given once clear the bloodstream of senescent or "zombie" cells.These cells contribute to multiple diseases and negative aspects of aging. Diseases including atherosclerosis (a form of heart disease), diabetes, and lung disease. As you age, these zombies build up in the body. They can make it difficult for your body to repair tissue, and they can release chemicals that harm normal cells nearby. This study shows that the removal of senescent cells significantly boosts the production of a protective protein called a-klotho.The protein a-klotho is important to maintaining good health, as it tends to decrease with age, and especially decreases in multiple diseases, including Alzheimer's, diabetes and kidney disease.  James Kirkland, M.D., Ph.D., a Mayo Clinic internist and senior author of the study., talked on these Senolytics drugs:“We show that there is an avenue for an orally active, small-molecule approach to increase this beneficial protein and also to amplify the action of senolytic drugs." Animal studies have shown that decreasing a-klotho in mice shortens life span and increasing a-klotho in mice by inserting a gene that causes its production increases life span by 30%. This study shows that senolytics increased a-klotho in humans with idiopathic pulmonary fibrosis, a senescence-associated disease that leads to frailty, serious breathing difficulties and death.   Tesla will open up Superchargers to non-Tesla electric vehicles in the US later this year - The Verge (24:23) Tesla plans to open up its Supercharger network to non-Tesla electric vehicles in the US in late 2022, according to a White House memo. The company has been allowing non-Tesla EVs to use its Supercharger plugs in several cities in Europe as part of a limited pilot program but has been quiet about when US charging stations would be available to non-Tesla EV owners.  The memo stated: “Later this year, Tesla will begin production of new Supercharger equipment that will enable non-Tesla EV drivers in North America to use Tesla Superchargers.” Tesla did not respond to an email seeking confirmation of these plans (Elon Musk disbanded the company's PR office in 2019). It's not clear whether the White House purposefully scooped Tesla's own announcement on this project. Tesla's Supercharger network is often held up as the best possible example of an EV charging network: fast, reliable, and plentiful.  This news is in line with what Tesla's CEO Elon Musk has, for years, about opening up his Superchargers to other companies' electric vehicles.  If the US version of the pilot program works the same as it does in Europe, non-Tesla EV owners will need to download the most recent version of Tesla's smartphone app in order to access the stations. They will be prompted to select “Charge Your Non-Tesla” in order to find the closest participating Supercharger site.  Tesla owners can still use the stations just as normal. 

CSB-SCB
14: Electromyography and Its Use to Control Prosthetics — Dr. Usha Kuruganti

CSB-SCB

Play Episode Listen Later Jul 4, 2022 48:48


Dr. Usha Kuruganti, Professor at the University of New Brunswick, discusses the use of electromyography signals to control prosthetic devices. She also explains some of her research on bilateral strength deficits in athletic, aging, and occupational contexts. 

Fitness Lit Breakdown with Dr. Nick Trubee
Do men & women use different muscles during the squat?

Fitness Lit Breakdown with Dr. Nick Trubee

Play Episode Listen Later Feb 28, 2022 35:03


There are some obvious differences between men & women related to exercising physiology. Hormonal, anatomical, and relative strength to name a few, but is there a difference in how each engages specific muscles during exercise? Some recent evidence may provide a window into this as a recent article shows differences in how men engage the hamstring muscles during the lowering phase of a squat compared to women. Now this may be important to note as injury risk to the knee tends to be higher in women compared to men in certain sports, and this could be a potential reason for that difference. In this episode I chat with Chad Trudo, CSCS, the Director of Strength & Conditioning for Aurora University and discuss how he assesses and programs his women athletes with these findings in mind.Article of reference:"Electromyography comparison of sex differences during the back squat"Journal of Strength & Conditioning Research 36(2)/310-313.

The Gestalt Education Show
Clinical Savant Series: Dr. Donald Dishman, Chiropractic Neurology

The Gestalt Education Show

Play Episode Listen Later Feb 23, 2022 41:44


Dr. Don Dishman is the Dean of Graduate Neuroscience degree programs at Parker University and has been teaching electrodiagnostics for over 30 years to physicians throughout the United States. In addition to teaching, Dr. Dishman's research publications have been featured in the Journal of Neuroscience Methods, Spine, Journal of Manipulative and Physiological Therapeutics, Electromyography, and clinical neurophysiology. Dr. Dishman has devoted much of his clinical and research career to explaining the neurophysiological effects of manipulation. We caught up with him right after his presentation at Parker Las Vegas. We recorded right in the middle of everything so excuse the audio! Enjoy! --- Support this podcast: https://anchor.fm/gestalt-education/support

Cycling Science Podcast
Episode 15- Incorporation of 30s sprints into your endurance ride, Dr Nicki Winfield Almquist interview

Cycling Science Podcast

Play Episode Listen Later Jan 6, 2022 73:40


In this episode I interview Dr Nicki Winfield Almquist who is a postdoctoral researcher at the University of Copenhagen, Denmark. We discuss one of his publications 'The Effect of 30-Second Sprints During Prolonged Exercise on Gross Efficiency, Electromyography, and Pedaling Technique in Elite Cyclists' published in the [[International Journal of Sports Physiology and Performance]]. https://journals.humankinetics.com/view/journals/ijspp/15/4/article-p562.xml. This paper is one of the studies in his PhD and thus our discussion does expand to include some of his other work. 

Neurology Clinical Pearls
Diagnosis of ALS (Part 2 of 2)

Neurology Clinical Pearls

Play Episode Listen Later Aug 17, 2021 14:02


Electromyography findings, diagnostic criteria, workup for fasciculations Dr. K. H. Vincent Lau interviewed by Dr. Lucas Horta

Generation Alpha
What is Functional Medicine w/ Dr. Michael Meighen

Generation Alpha

Play Episode Listen Later May 28, 2021 87:21


This week on the Generation Alpha Podcast we have another all-star guest, Michael Meighen sat down with DrCharlie Ware and I to talk about Functional and Precision Medicine and to discuss some of the unique practices Michael utilizes to help take care of his patients. Michael is a former athlete turned Functional Medicine and Health Optimization Expert. Michael has over 20 years of experience in Body Restoration and Physical Rehabilitation. He is an Amazon #1 Best selling Author and the founder of his business Live Limitless LLC, utilizing a variety of different skills and knowledge tools to help heal the human body and mind including: Electromyography, Joint aspiration, osteopathic manipulation techniques and treatments, acupuncture, and ultrasound treatments just to name a few. This is definitely one the most interesting guests I've had on so far so you don't want to miss this one

High Intensity Business
312 - Dr. Bryce Lee - What is the Best Way to Utilise the MedX Overhead Press?

High Intensity Business

Play Episode Listen Later Mar 24, 2021 66:30


Dr. Bryce Lee (bryce @ strength-space.com) is the Director of Therapy and Co-founder of StrengthSpace, a fitness studio that provides clients with resistance training and physical therapy services in Chesapeake, VA. His doctoral program focuses on orthopaedics, pain neuroscience, the relationship between systemic inflammation and “mechanical” disorders such as osteoarthritis and tendinopathy.  In this episode, Bryce talks about the settings, biomechanics, and instruction around the MedX Overhead Press to help you train your clients better. You’ll learn how to coach clients on the MedX Overhead Press, proper seat and grip positions, implementing different exercise protocols, and much more.   Learn how to train clients with other MedX Exercise Machines: 303 – Tim Ryan on Selling a HIT Studio Business, Starting Anew, and Training Clients on the MedX Avenger Leg Press 299 – Craig Hubert – How to Setup, Supervise, and Succeed with the MedX Chest Press 294 – Luke Carlson – How to Coach, Configure, and Conquer with the MedX Leg Press 262 – Dr Doug McGuff – How More Contractions may Increase Muscle Growth, Training with a Newborn, and MedX Medical Machines   Become a successful HIT business owner For all of the show notes, links, and resources - Click Here

BrainWaves: A Neurology Podcast
Best of BrainWaves 2020

BrainWaves: A Neurology Podcast

Play Episode Listen Later Dec 31, 2020 67:47


Happy New Year, and good riddance 2020! Hopefully there is more that you will take away from the past 12 months other than your personal experience with the coronavirus pandemic. Whether you lost a job, a loved one, or an invaluable life experience, I think we can all say BRING ON 2021! So let's welcome the new year with positive mental attitude, a bit more luck, and an unquenchable thirst for knowledge. Produced by James E. Siegler. Music courtesy of Jahzzar, Kevin McLeod, Patches, Montplaisir, Steve Combs, Lee Roosevere, Siddhartha, Soft and Furious, Magic in the Other, and Loyalty Freak Music. The opening theme was composed by Jimothy Dalton. Sound effects by Mike Koenig and Daniel Simion. Unless otherwise mentioned in the podcast, no competing financial interests exist in the content of this episode. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES EEG Wiebe S, Blume WT, Girvin JP, Eliasziw M, Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study G. A randomized, controlled trial of surgery for temporal-lobe epilepsy. The New England journal of medicine. 2001;345:311-8. Cascino GD. Clinical indications and diagnostic yield of video-electroencephalographic monitoring in patients with seizures and spells. Mayo Clinic proceedings. 2002;77:1111-20. Pillai J and Sperling MR. Interictal EEG and the diagnosis of epilepsy. Epilepsia. 2006;47 Suppl 1:14-22. Bouma HK, Labos C, Gore GC, Wolfson C and Keezer MR. The diagnostic accuracy of routine electroencephalography after a first unprovoked seizure. European journal of neurology : the official journal of the European Federation of Neurological Societies. 2016;23:455-63. Debicki DB. Electroencephalography after a single unprovoked seizure. Seizure. 2017;49:69-73. DYSFERLINOPATHY Suresh E and Wimalaratna S. Proximal myopathy: diagnostic approach and initial management. Postgraduate medical journal. 2013;89:470-7. Walter MC, Reilich P, Thiele S, Schessl J, Schreiber H, Reiners K, Kress W, Muller-Reible C, Vorgerd M, Urban P, Schrank B, Deschauer M, Schlotter-Weigel B, Kohnen R and Lochmuller H. Treatment of dysferlinopathy with deflazacort: a double-blind, placebo-controlled clinical trial. Orphanet J Rare Dis. 2013;8:26. Fayssoil A, Ogna A, Chaffaut C, Chevret S, Guimaraes-Costa R, Leturcq F, Wahbi K, Prigent H, Lofaso F, Nardi O, Clair B, Behin A, Stojkovic T, Laforet P, Orlikowski D and Annane D. Natural History of Cardiac and Respiratory Involvement, Prognosis and Predictive Factors for Long-Term Survival in Adult Patients with Limb Girdle Muscular Dystrophies Type 2C and 2D. PloS one. 2016;11:e0153095. Harris E, Bladen CL, Mayhew A, James M, Bettinson K, Moore U, Smith FE, Rufibach L, Cnaan A, Bharucha-Goebel DX, Blamire AM, Bravver E, Carlier PG, Day JW, Diaz-Manera J, Eagle M, Grieben U, Harms M, Jones KJ, Lochmuller H, Mendell JR, Mori-Yoshimura M, Paradas C, Pegoraro E, Pestronk A, Salort-Campana E, Schreiber-Katz O, Semplicini C, Spuler S, Stojkovic T, Straub V, Takeda S, Rocha CT, Walter MC, Bushby K and Jain COSC. The Clinical Outcome Study for dysferlinopathy: An international multicenter study. Neurol Genet. 2016;2:e89. Clark KEN and Isenberg DA. A review of inflammatory idiopathic myopathy focusing on polymyositis. European journal of neurology : the official journal of the European Federation of Neurological Societies. 2018;25:13-23. Wicklund MP. The Limb-Girdle Muscular Dystrophies. Continuum (Minneap Minn). 2019;25:1599-1618. Preston DC and Shapiro BE. Electromyography and neuromuscular disorders: clinical-electrophysiologic correlations. 3rd ed. London; New York: Elsevier Saunders; 2013. “rAAVrh74.MHCK7.DYSF.DV for Treatment of Dysferlinopathies.” Clinicaltrials.gov. Retrieved from https://clinicaltrials.gov/ct2/show/NCT02710500?cond=dysferlinopathy&draw=2&rank=1 on 22 December 2019. SPINAL DURAL AV FISTULA Jellema K, Tijssen CC, van Rooij WJ, Sluzewski M, Koudstaal PJ, Algra A and van Gijn J. Spinal dural arteriovenous fistulas: long-term follow-up of 44 treated patients. Neurology. 2004;62:1839-41. Mull M, Nijenhuis RJ, Backes WH, Krings T, Wilmink JT and Thron A. Value and limitations of contrast-enhanced MR angiography in spinal arteriovenous malformations and dural arteriovenous fistulas. AJNR American journal of neuroradiology. 2007;28:1249-58. Krings T and Geibprasert S. Spinal dural arteriovenous fistulas. AJNR American journal of neuroradiology. 2009;30:639-48. Alexander MD, Oliff MC, Olorunsola OG, Brus-Ramer M, Nickoloff EL and Meyers PM. Patient radiation exposure during diagnostic and therapeutic interventional neuroradiology procedures. J Neurointerv Surg. 2010;2:6-10. Cifarelli CP, Kaptain G, Yen CP, Schlesinger D and Sheehan JP. Gamma knife radiosurgery for dural arteriovenous fistulas. Neurosurgery. 2010;67:1230-5; discussion 1235. Kim DJ, Willinsky R, Geibprasert S, Krings T, Wallace C, Gentili F and Terbrugge K. Angiographic characteristics and treatment of cervical spinal dural arteriovenous shunts. AJNR American journal of neuroradiology. 2010;31:1512-5. Chen J and Gailloud P. Safety of spinal angiography: complication rate analysis in 302 diagnostic angiograms. Neurology. 2011;77:1235-40. Manninen AL, Isokangas JM, Karttunen A, Siniluoto T and Nieminen MT. A comparison of radiation exposure between diagnostic CTA and DSA examinations of cerebral and cervicocerebral vessels. AJNR American journal of neuroradiology. 2012;33:2038-42.

PMR Lady Docs
Canadian PMR-featuring Dr. Agnes Chmiel

PMR Lady Docs

Play Episode Listen Later Sep 30, 2020 49:05


Interested in learning what PMR is like in Canada? In our On Call series, the PMR Lady Docs interview various specialists in the medical field. In this episode we interview Dr. Agnes Chmiel, Medical Director of Inpatient Spinal Cord Injury Rehabilitation at the Regional Rehabilitation Centre in Hamilton, Ontario, Canada. Her outpatient focus is Spasticity Management, Electromyography, and Musculoskeletal Rehabilitation. She is also an Associate Clinical Professor at McMaster University and Fellowship Director. Date of recording: August 29, 2020.Host: Marjorie MamsaangCo-Hosts: Patricia Goodwin, Shiel Jhaveri and Tricia Prince Guest: Dr. Agnes ChmielProduced and edited by: Tricia Prince

The Optimal Body
27 | Evaluating Research with Biomechanist and Professor, Dr. Scott Lynn

The Optimal Body

Play Episode Listen Later Aug 31, 2020 50:50


Join us as Dr. Scott Lynn, Jen's very own Biomechanics PhD professor from California State University, Fullerton, breaks down the research of biomechanics and brings us back to the individual in movement. With his background working in professional sports like baseball and golf, over 20 years of publishing and reviewing research articles and journals, Dr. Lynn has uncovered the best ways to avoid injury and optimize our movement patterns. Listen as he unleashes all of his biomechanical wisdom on how you can achieve optimal movement. Lastly, tune in as we breakdown what the Coba Board is, why Dr. Lynn is involved, and how his own research on this tool reveals how it can help you achieve optimal glute activation in both a squat and hinge pattern. Get your own Coba Board to start building that booty! Use code "DOCJENFIT" at checkout: https://cobaboard.com/?rfsn=4420402.cbcd73&utm_source=refersion&utm_medium=affiliate&utm_campaign=4420402.cbcd73 What You Will Learn in this interview with Dr. Scott Lynn: @drsklynn 04:35 – Dr. Lynn’s approach in the classroom - Why it is effective for both students and teachers 06:51 – How human movement is still unknown and a mystery to us 09:29 – How Dr. Lynn became interested in biomechanics and human movement - Why your job should be more than the paycheck 15:30 – How long Dr. Lynn has been researching and the differences he's noticed over time 20:31 – How to decipher research and its reliability - How “messy” human beings are 24:02 – Why the “best” exercise or movement pattern doesn't exist - Why movement is individual 25:51 – Dr. Lynn explaining FMS theory (functional magnetic stimulation) and why he studied it 31:37 – What Dr. Lyn found researching FMS - Why variability in exercise is necessary 40:26 – What the Coba Board is and how Dr. Lynn got involved with it About Dr. Scott Lynn: Dr. Scott K. Lynn received his Bio- PhD, MSc in Orthopedic Biomechanics at Queen's University, Canada. He received his Post-Doctoral Fellowship in Spine Biomechanics at the University of Waterloo, Canada. Currently, he is a professor in Kinesiology (Biomechanics) at California State University, Fullerton. Dr. Lynn is also the Director of Research & Education for the Center for Sport Performance at California State University Fullerton. He is the creator of the video analysis software Swing Catalyst (Sport Technology company focusing on Golf and Baseball biomechanics). Dr. Lynn has been published by many peer reviewed research articles and book chapters related to golf biomechanics, exercise biomechanics & rehabilitation. Journals published in include: Journal of Strength and Conditioning Research, Strength and Conditioning Journal, International Journal of Golf Science Journal of Sports Rehabilitation, Clinical Biomechanics, Journal of Science and Medicine in Sports Human Movement Science, Journal of Sports Science and Medicine, Medicine and Science of Sports and Exercise Journal of Electromyography, and Kinesiologist. To see Dr. Scott Lynn's full bio and links to his book and website, head over to the complete show notes here: www.docjenfit.com/podcast/episode27 --- Send in a voice message: https://anchor.fm/TOBpodcast/message

Cutternation Podcast
Cutternation Podcast #94 - Arnel Aguinaldo

Cutternation Podcast

Play Episode Listen Later Jun 30, 2020 64:21


Cutternation Podcast #94 - Arnel Aguinaldo Professor Arnel Aguinaldo (or Professor "A" as his students call him) has been an adjunct instructor at PLNU since spring 2013, and an assistant professor of kinesiology in the M.S. program since fall 2015. He has also served as an adjunct professor at San Diego State University in the Department of Exercise and Nutritional Sciences, where, since 2005, he has taught undergraduate and graduate level courses in Biomechanics of Human Movement, Statistics in Kinesiology, Research Methods, Electromyography, and Functional Human Movement. www.cutternation.net --- Support this podcast: https://anchor.fm/cutternation/support

Sports Biomechanics Lecture Series
Lecture 19 - Delsys - Electromyography (EMG) in Sports Biomechanics

Sports Biomechanics Lecture Series

Play Episode Listen Later Jun 25, 2020 43:44


Lecture 19 of the Sports Biomechanics Lecture Series #SportsBiomLS 

lecture electromyography sports biomechanics
DMCN Journal
Wearable Electromyography Recordings: Daily Life in Children with Cerebral Palsy | Lorentzen | DMCN

DMCN Journal

Play Episode Listen Later Jun 9, 2020 2:46


In this podcast Jakob Lorentzen discusses his paper 'Wearable electromyography recordings during daily life activities in children with cerebral palsy'. The paper is available here: https://onlinelibrary.wiley.com/doi/full/10.1111/dmcn.14466 ___ DMCN Journal: Developmental Medicine & Child Neurology (DMCN) has defined the field of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families.   DMCN Journal - https://onlinelibrary.wiley.com/journal/14698749 ___ Watch DMCN videos on our YouTube channel: https://bit.ly/2ONCYiC   Find us on Twitter! @mackeithpress - https://twitter.com/mackeithpress

Did you move today?
EP 49 Meet Dr. Brooke Winder and Move with Her!

Did you move today?

Play Episode Listen Later Apr 18, 2020 35:05


Brooke Winder, PT, DPT, OCS Doctor of Physical Therapy Board Certified Specialist in Orthopedic Physical Therapy Pelvic Health Specialist Brooke is a Southern California-based physical therapist specializing in orthopedic and pelvic floor health for dancers. She also serves as Assistant Professor in the Department of Dance at California State University, Long Beach, where she Coordinates the Bachelor's degree program in Dance Science and teaches courses in Anatomy, Injury Prevention, Wellness and Pilates. She is a member of the International Association of Dance Medicine and Science, Performing Arts Medicine Association, and Performing Arts Special Interest Group of the Academy of Orthopedic Physical Therapy. Brooke provides backstage care for touring professional dance companies, physical therapy services for summer dance intensives, and community workshops to dancers and dance educators. She is also passionate about educating the dance world about pelvic floor issues such as incontinence, prolapse, and pelvic pain, and empowering dancers to know how to address these symptoms. She has previously published in The Journal of Orthopedic and Sports Physical Therapy, Journal of Electromyography and Kinesiology, and Orthopedic Physical Therapy Practice magazine. She has presented research at venues such as the International Association of Dance Medicine and Science Annual Conference and the Performing Arts Medicine Association International Symposium. Brooke earned a Doctorate in Physical Therapy from the University of Southern California and a Bachelor of Fine Arts in Dance from Chapman University. She is a Board-Certified Specialist in Orthopedic Physical Therapy, a Certified Pilates instructor through Body Arts and Science International, and a former professional dancer with Orange County-based Backhausdance. IG: @drbrookewinderpt --- Send in a voice message: https://anchor.fm/didyoumovetodayco/message Support this podcast: https://anchor.fm/didyoumovetodayco/support

Health Made Easy with Dr. Jason Jones
The Most Common Spinal Disc Problems

Health Made Easy with Dr. Jason Jones

Play Episode Listen Later Mar 10, 2020 6:03


Spinal discs act as a cushion between the spinal vertebrae and they create space for the spinal nerves to exit the spine. Spinal discs have a hard exterior that provides support and enables a wide range of motion. They can be likened as a shock absorber that protects your spine. Pain is felt around the spinal disc as a result of the deterioration and break down of spinal discs, which can be very mild to severe.   Visit Dr. Jason Jones at our Chiropractic Office in Elizabeth City, NC, to help you get relief from pain as a result of spinal disc problems.   There are two common problems associated with the spinal disc. They include the following:   1. Herniated disc Studies have shown that herniated spinal disc problem occurs as a result of protrusion of the inner disc material through a small tear on the disc. The protrusion of the spinal discs causes more pain than a bulging disc. Herniated disc problem is common among the younger population typically due to trauma.   Symptoms of herniated spinal disc problems include the following: Pain in the lower back or leg Cramping or muscle spams Tingling, weakness or a numbness sensation in the affected area. Pain tends to worsen when sitting or leaning forward. Feeling of pain when coughing, sneezing or lifting objects. Diagnosis:  Your Chiropractor needs to carry out a proper diagnosis to determine the main cause of your herniated disc problem before carrying out treatment. By paying a visit to Dr. Jason Jones at our Chiropractic Office in Elizabeth City, NC, you are sure to get a proper physical examination and, if necessary, refer out for an MRI assessment of the affected area.   2. Degenerative Disc Disease Degenerative disc disease is a spinal disc problem that can be responsible for some cases of neck and lower back pain. It occurs as a result of a spinal disc breaking down. Degenerative disc disease is common among those who are elderly but can begin much earlier in life. According to research, Loss of spinal fluid and cracking of the spinal disc can lead to degenerative disc disease.   Symptoms of degenerative disc disease The symptoms of degenerative disc disease occur gradually and increase with time. They include the following: Pain in the lower back or neck. Feeling of pain which restricts certain movement like bending or reaching up. Less pain is felt when walking, lying down or running. Stiffness and restricted movement after being sedentary   Diagnosis:  A detailed history, as well as neurological or physical examination, is carried out to ascertain the cause of the degenerative disc disease. X-ray, MRI or CT and Electromyography are diagnostic techniques that may be employed in finding out if you have degenerative disc disease.   The symptoms of spinal disc problems can be very painful. It is important to visit an experienced Chiropractor who will provide proper spinal alignment through several hands-on techniques.   

BrainWaves: A Neurology Podcast
#158 Teaching through clinical cases: A primer on proximal weakness

BrainWaves: A Neurology Podcast

Play Episode Listen Later Mar 5, 2020 18:36


Generalized weakness is a common complaint. Much of the time, we as neurologists don’t even see these patients in the hospital or the clinic. But more often than not, “generalized” weakness may be the only way a patient describes difficulty brushing their hair or climbing stairs. In these situations, it’s not exactly generalized weakness. It’s something else. This week on BrainWaves, we review the major patterns of weakness that characterize the most common muscle disorders. With a quick review of EMG findings. Enjoy! Produced by James E. Siegler. Music courtesy of Jahzzar, Kevin McLeod, Patches, and Montplaisir. Unless otherwise mentioned in the podcast, no competing financial interests exist in the content of this episode. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES Suresh E and Wimalaratna S. Proximal myopathy: diagnostic approach and initial management. Postgraduate medical journal. 2013;89:470-7. Walter MC, Reilich P, Thiele S, Schessl J, Schreiber H, Reiners K, Kress W, Muller-Reible C, Vorgerd M, Urban P, Schrank B, Deschauer M, Schlotter-Weigel B, Kohnen R and Lochmuller H. Treatment of dysferlinopathy with deflazacort: a double-blind, placebo-controlled clinical trial. Orphanet J Rare Dis. 2013;8:26. Fayssoil A, Ogna A, Chaffaut C, Chevret S, Guimaraes-Costa R, Leturcq F, Wahbi K, Prigent H, Lofaso F, Nardi O, Clair B, Behin A, Stojkovic T, Laforet P, Orlikowski D and Annane D. Natural History of Cardiac and Respiratory Involvement, Prognosis and Predictive Factors for Long-Term Survival in Adult Patients with Limb Girdle Muscular Dystrophies Type 2C and 2D. PloS one. 2016;11:e0153095. Harris E, Bladen CL, Mayhew A, James M, Bettinson K, Moore U, Smith FE, Rufibach L, Cnaan A, Bharucha-Goebel DX, Blamire AM, Bravver E, Carlier PG, Day JW, Diaz-Manera J, Eagle M, Grieben U, Harms M, Jones KJ, Lochmuller H, Mendell JR, Mori-Yoshimura M, Paradas C, Pegoraro E, Pestronk A, Salort-Campana E, Schreiber-Katz O, Semplicini C, Spuler S, Stojkovic T, Straub V, Takeda S, Rocha CT, Walter MC, Bushby K and Jain COSC. The Clinical Outcome Study for dysferlinopathy: An international multicenter study. Neurol Genet. 2016;2:e89. Clark KEN and Isenberg DA. A review of inflammatory idiopathic myopathy focusing on polymyositis. European journal of neurology : the official journal of the European Federation of Neurological Societies. 2018;25:13-23. Wicklund MP. The Limb-Girdle Muscular Dystrophies. Continuum (Minneap Minn). 2019;25:1599-1618. Preston DC and Shapiro BE. Electromyography and neuromuscular disorders: clinical-electrophysiologic correlations. 3rd ed. London; New York: Elsevier Saunders; 2013. “rAAVrh74.MHCK7.DYSF.DV for Treatment of Dysferlinopathies.” Clinicaltrials.gov. Retrieved from https://clinicaltrials.gov/ct2/show/NCT02710500?cond=dysferlinopathy&draw=2&rank=1 on 22 December 2019. For great video examples of EMG findings in nerve and muscle disease, check out KImura & Kohara's YouTube recordings: https://www.youtube.com/watch?v=6-3PP_S-Q8I&list=PLCC_NQWOABCY18PEzlGELGOR_-IDNaDQ_

The Stronger By Science Podcast
Metabolic Rate, Artificial Sweeteners, Electromyography, and Non-Failure Training

The Stronger By Science Podcast

Play Episode Listen Later Feb 13, 2020 190:46


Just in time for Valentine’s Day, Greg and Eric are back with another episode. First, Greg shares some recent Feats of Strength. Next, Greg & Eric answer some listeners’ questions about topics such as resting metabolic rate prediction equations, electromyography, vitamin D and fish oil supplementation, standing desks, and more. That’s followed by a Research Roundup segment, which covers recent research on plant-based proteins, training shy of failure, and artificial sweeteners, in addition to a critical review of “Why We Sleep.” Finally, the relationship between lifting technique and injury risk is discussed in a brief Coach’s Corner segment, and Greg shares some sous vide cooking tips to close out the episode.Time Stamps(0:00:26) Happy Valentine’s Day from the Stronger By Science Family.(0:02:41) Feats of Strength.Q&A:(0:14:06) Can you cover the (in)accuracy of online RMR calculators?(0:25:34) Lots of questions about EMG, stemming from the recent Barbalho study.Study link: https://www.ncbi.nlm.nih.gov/pubmed/31975359. (0:40:10) I've heard that having additional muscle mass can have effects on metabolism. Is this true?(0:44:58) When combining unilateral and bilateral training in the same session, is it more advantageous to do unilateral or bilateral first?(0:50:53) Do either of you guys still see a point in vitamin D and fish oil supplementation?(1:23:19) If I was born with poor lifting genes, yet continued to perform resistance exercises out of passion, and then give birth to a child who inherited my poor genes, who also performed resistance exercise...how many generations of children would be needed before a noticeable difference in lifting-specific genes was present?(1:32:16) Are standing desks scientifically any better for athletes then sitting all day and how is that quantifiable?Research Roundup(1:42:43) Differential Responses of Blood Essential Amino Acid Levels Following Ingestion of High-Quality Plant-Based Protein Blends Compared to Whey Protein-A Double-Blind Randomized, Cross-Over, Clinical Trial. Study: https://www.ncbi.nlm.nih.gov/pubmed/31817691. (1:51:41) Non-failure training for strength. Study: https://www.ncbi.nlm.nih.gov/pubmed/26666744. (2:06:32) Artificial sweeteners.Effects of Stevia Extract on Postprandial Glucose Response, Satiety and Energy Intake: A Three-Arm Crossover Trial. Study: https://www.ncbi.nlm.nih.gov/pubmed/31842388. Short-Term Impact of Sucralose Consumption on the Metabolic Response and Gut Microbiome of Healthy Adults. Study: https://www.ncbi.nlm.nih.gov/pubmed/31258108.(2:28:04) A critical review of “Why We Sleep.” Article: https://guzey.com/books/why-we-sleep/.(2:43:39) Coach’s Corner: Lifting technique and injury risk. Roundtable link: https://www.youtube.com/watch?v=Tt1869DNYLY.(2:54:45) To Play Us Out: Sous vide cooking tips.

Spine and Nerve podcast
Small investment, big rewards- why the electrodiagnostic evaluation should be a part of your workup

Spine and Nerve podcast

Play Episode Listen Later Oct 1, 2019 25:23


In this week's episode of the Spine & Nerve podcast, Dr. Nicolas Karvelas and Dr. Brian Joves are introducing electrodiagnostic evaluations. An electrodiagnostic evaluation is a combination of nerve conduction studies and electromyography, or in simple terms a way to look at the health of nerves. The nerve conduction study uses electrodes and an electrical impulse to send a signal through a nerve and pick it up at a different point along that nerve. Electromyography is a small needle (usually 28g) that goes into muscles and listens to the way the muscle and nerves communicate. This study is performed by mainly two specialties- neurologists and physiatrists. It is considered by many to be an extension of they physical examination, and part of the normal workup for pathologies just like imaging (MR or XR) is. Electrodiagnostic evaluations can help assess many pathologies, but the must common are things like carpal tunnel syndrome, peripheral neuropathy, and radiculopathy (nerve root injury originating at they level of the spine). These studies are also integral in the evaluation of more rare processes like muscular dystrophy, ALS, and other neuromuscular diseases; but the docs stick to the more common pathologies in this discussion. Listen in for some key takeaways including: - the study is uncomfortable, but overall well tolerated - Generally, In less than an hour we can have some very useful and objective data - This tool is a very helpful and useful part of a full workup for the patient Follow our practice on Facebook at Spine & Nerve Diagnostic Center. Please leave us a comment or review- these help us to improve and provide value to more people. This podcast is for information and educational purposes only, it is not meant to be medical advice. If anything discussed may pertain to you, please seek council with your healthcare provider. The views expressed are those of the individuals expressing them, they may not represent the views of Spine & Nerve.

Simply PM&R
Moving the Needle – What’s New in Electromyography

Simply PM&R

Play Episode Listen Later Aug 27, 2019 15:49


Guest: Andrea J. Boon, M.D. Host: Jeffrey S. Brault, D.O. (@JeffBrault) When is it appropriate to order an electromyography (EMG)? How early is too early to get results? When do you run the nerve conduction and/or the needle exam? Dr. Andrea Boon discusses how to best approach the needle exam and which muscles are the best to needle. Neuromuscular ultrasound is playing in electrodiagnostics and conditions like carpel tunnel syndrome? Dr. Boon shares her pearls for utilizing ultrasound and calling myopathies and radiculopathies. Connect with the Mayo Clinic’s PM&R Department on Twitter @MayoClinicPMR. 

Decoding Superhuman
The HIIT Deep Dive with Dr. Paul Laursen

Decoding Superhuman

Play Episode Listen Later Jun 3, 2019 46:55


High-Intensity Interval Training is a popular format of exercise to get more done with less time. The research behind HIIT for both physical and mental benefits is convincing. Dr. Paul Laursen joins the show to discuss HIIT in detail. Who is Dr. Paul Laursen? Dr. Paul Laursen resides at the nexus between exercise performance research, theory, and application. He is an Adjunct Professor of Exercise Physiology at AUT University in New Zealand where he leads research into low carb diet and its performance applications. Dr. Laursen has published over 130 peer-reviewed papers and is a co-founder of HIIT Science, which serves to teach The Science and Application of High-Intensity Interval Training (see book and online course). He coaches a select number of elite triathletes, including Kyle Buckingham, and is the inventor of Floe Bottle, which enables ice slushy delivery for hot racing conditions. Highlights [2:33] Our mutual connection, Jason Moore [3:01] What is high-intensity interval training? [10:03] Sample HIIT programming [21:42] Electromyography [22:45] The problem with programs prescribed to the masses [25:57] HPA Axis and HIIT [28:44] HRV and HIIT [32:03] The Five HIIT Weapons [37:33] Paul Laursen answers the Finishing Four Resources HIIT Science Website Why We Sleep by Dr. Matthew Walker Awaken the Giant Within by Anthony Robbins The 4 Hour Work Week by Tim Ferriss Waking Up by Sam Harris Waking Up App The Throwdown Continue Your Journey with Dr. Paul Laursen Instagram Twitter Facebook Sponsor What brands of blue light blockers do we recommend? BluBlox is definitely a go to. The CEO Andy Mant on the show before where we got into a really deep dive on blue light. If you get any amount of blue light in your glasses, no matter if it’s 3%, 10%, it disrupts melatonin production. So Andy has created blue light blockers that hold up to the highest standards. And in fact, you can see he’s tested it versus other brands and that they always come out on top. Quality matters. If you head over to blublox.com and plug in the code “DS15”, you’re going to get 15% off your order. Disclaimer This information is being provided to you for educational and informational purposes only. This is being provided as a self-help tool to help you understand your genetics, biodata and other information to enhance your performance. It is not medical or psychological advice. Virtuosity LLC is not a doctor. Virtuosity LLC is not treating, preventing, healing, or diagnosing disease. This information is to be used at your own risk based on your own judgment. For the full Disclaimer, please go to (Decodingsuperhuman.com/disclaimer). See acast.com/privacy for privacy and opt-out information.

AANEM Presents Nerve and Muscle Junction
Needle Electromyography and Histopathologic Correlation in Myopathies

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Apr 29, 2019 14:43


Dr. Behzad Elahi interviews Dr. Devin I. Rubin on his article, Needle Electromyography and Histopathologic Correlation in Myopathies. Fibrillation potentials and short-duration MUPs predict pathologic changes of muscle fiber necrosis, splitting, and/or vacuolar changes (as seen with inflammatory myopathies and muscular dystrophies). Absence of fibrillation potentials suggests other myopathologic changes (e.g., congenital myopathy). Muscle Nerve 59:315-320, 2019.

AANEM Presents Nerve and Muscle Junction
Needle Electromyography and Histopathologic Correlation in Myopathies

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Apr 29, 2019 14:43


Dr. Behzad Elahi interviews Dr. Devin I. Rubin on his article, Needle Electromyography and Histopathologic Correlation in Myopathies. Fibrillation potentials and short-duration MUPs predict pathologic changes of muscle fiber necrosis, splitting, and/or vacuolar changes (as seen with inflammatory myopathies and muscular dystrophies). Absence of fibrillation potentials suggests other myopathologic changes (e.g., congenital myopathy). Muscle Nerve 59:315-320, 2019.

AANEM Presents Nerve and Muscle Junction
Needle Electromyography and Histopathologic Correlation in Myopathies

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Apr 24, 2019 14:43


Dr. Behzad Elahi interviews Dr. Devin I. Rubin on his article, Needle Electromyography and Histopathologic Correlation in Myopathies. Fibrillation potentials and short-duration MUPs predict pathologic changes of muscle fiber necrosis, splitting, and/or vacuolar changes (as seen with inflammatory myopathies and muscular dystrophies). Absence of fibrillation potentials suggests other myopathologic changes (e.g., congenital myopathy). Muscle Nerve 59:315-320, 2019.

Train by Science Podcast for Cyclists and Endurance Athletes
שלושת הפרמטרים שקובעים את הסף שלכם

Train by Science Podcast for Cyclists and Endurance Athletes

Play Episode Listen Later Jan 8, 2019 59:55


במהלך הפרק אני מפרט על שלושת הפרמטרים שקובעים את הסף שלכם: צריכת חמצן מירביתאחוז מצריכת חמצן מירבית שאתם מסוגלים להחזיקיעילותאני מסביר את כל אחד מהפרמטרים הנ״ל וכן דן באינטראקציה ביניהם ואיך אתם יכולים לשפר את כל אחד מהמרכיבים האלה. במסגרת הפרק אני מראיין את ד״ר אילן קורץ, מרצה לפיזיותרפיה באוניברסיטת בן גוריון, והוא מסביר לנו על מגוון רחב של מחקרים שבוצעו בנוגע יעילות ואיך אפשר לדעתו לשפר אותה. Articles mentioned in the episode:The effect of Q factor on gross mechanical efficiency and muscular activation in cycling. Disley BX1, Li FX.Inverse relationship between VO2max and economy/efficiency in world-class cyclists. Lucía A, et al. Med Sci Sports Exerc. 2002.Arkesteijn, Marco and Jobson, Simon A. and Hopker, James G. and Passfield, Louis (2016) The effect of cycling intensity on cycling economy during seated and standing cycling. International journal of sports physiology and performance, 11 (7). pp. 907-912. ISSN 1555-0265Inverse relationship between VO2max and economy/efficiency in world-class cyclists. Lucía A1, Hoyos J, Pérez M, Santalla A, Chicharro JL.Candotti, C. T., Loss, J. F., Bagatini, D., Soares, D. P., da Rocha, E. K., de Oliveira, Á. R., & Guimarães, A. C. S. (2009). Cocontraction and economy of triathletes and cyclists at different cadences during cycling motion. Journal of Electromyography and Kinesiology, 19(5), 915–921.Improved muscular efficiency displayed as Tour de France champion matures Edward F. CoyleEfficiency in cycling: a review Gertjan Ettema Æ Ha ̊vard Wuttudal Lora ̊s

NPTE Clinical Files
Electromyography

NPTE Clinical Files

Play Episode Listen Later May 16, 2018 10:43


Daniel is a 17 year old male who fell off a ladder fracturing his proximal tibia. The patient has severed his common peroneal nerve and is undergo EMG. The physical therapist is challenged with anticipating what readings will show up on the patient's EMG report.  We will uncover the answer in this excellent episode about Electromyography.  Are you in the free facebook group called, #smartnpteprep? Get access to test-taking strategies, live discussions, question & answers, and the most effective study tips. Come on in and join us! Click the link: bit.ly/SNPGroup

BrainWaves: A Neurology Podcast
#90 Conduction block, and why it confuses me

BrainWaves: A Neurology Podcast

Play Episode Listen Later Dec 21, 2017 21:04


Nerve conduction testing should not be as puzzling as it's made out to be. This week, we break it down into individual components and use two case examples to explain how you might interpret this commonly implemented electrodiagnostic assessment. Produced by James E. Siegler. Music by Coldnoise, Jessie Spillane, Loyalty Freak Music, and Yshwa. Voiceover by Erika Mejia. BrainWaves' podcasts and online content are intended for medical education only and should not be used for routine clinical decision making. REFERENCES Allen JA. Chronic Demyelinating Polyneuropathies. Continuum (Minneap Minn). 2017;23:1310-1331. Kincaid JC. Neurophysiologic Studies in the Evaluation of Polyneuropathy. Continuum (Minneap Minn). 2017;23:1263-1275. Preston DC and Shapiro BE. Electromyography and neuromuscular disorders : clinical-electrophysiologic correlations. 3rd ed. London ; New York: Elsevier Saunders; 2013. Pareyson D, Scaioli V and Laura M. Clinical and electrophysiological aspects of Charcot-Marie-Tooth disease. Neuromolecular Med. 2006;8:3-22.

Circle of Willis
John Cacioppo Bonus Material

Circle of Willis

Play Episode Listen Later Nov 22, 2017 23:55


Hey Everyone! This is not a full episode of my podcast Circle of Willis! What this is…this is BONUS MATERIAL from Episode 6, where I talked with JOHN CACIOPPO. This is material that might be a little tougher for some people—people who are not social psychologists or psychophysiologists… But if you are one of those people, or if you're comfortable doing a little google searching, there is some great stuff here. It’s me and John Cacioppo talking about the work John did with Richard Petty on the Elaboration Likelihood Model, John’s methodological work on the field of Electromyography (see the awesome image at the right for the picture John and I laugh about), John’s willingness to forgo tenure in order to do the science correctly…good stuff! And of course at some point John and I just started to geek out about the early days of a discipline called psychophysiology. We talk a bit about how psychophysiologists can easily get really focused on their physiological specialty. It was great fun for me and I hope it's enjoyable for you, too!  

Circle of Willis
Episode 6: John Cacioppo

Circle of Willis

Play Episode Listen Later Nov 17, 2017 47:03


Welcome to Episode 6, where Professor JOHN CACIOPPO and I talk about inferring causal associations between mind and body, and how to be human is to care for others.   John is the Tiffany and Margaret Blake Distinguished Service Professor, and the founder and director of the Center for Cognitive and Social Neuroscience, at the University of Chicago   John’s contributions to the fields of Social Psychology, Psychophysiology, Social Neuroscience (an entire field he helped create more or less from scratch), research methodology, philosophy of science…on and on…would be hard or impossible to overstate. He is a quasi-religious figure to me in that I’ve been reading his methodological critiques and recommendations about mind-body research, as well as his work on the Elaboration Likelihood Model, Electromyography, and Loneliness, for my entire career. I’ve described his groundbreaking book, PRINCIPLES OF PSYCHOPHYSIOLOGY (later, the HANDBOOK OF PSYCHOPHYSIOLOGY) as the holy text of my scholarly origin story, and I mean it. It was published in 1990, right about the time I went back to college as a nervous 21-year-old, and soon after going to work in John Gottman’s lab. There, the book was literally required reading. As I moved through graduate school and well into my career, John has been a guide to the work I do, conceptually, methodologically, and philosophically, and the same can be said of a relatively unknown ocean of researchers all across the globe.    John’s recent popular book, LONELINESS, covers decades of work he and others have done documenting the cost of social isolation, whether “objective” isolation (as he calls it) or perceived. It turns out that perceived isolation may be the most harmful of the two kinds, and in any case, isolation kills. We are not a species that relies on our own resources to survive just long enough to reproduce. We are a species that cares for others, and that expects to be cared for.    At any rate, I hope you enjoy this chance to spend a little time with one of psychology’s most prolific and restless minds. I know I did.    *    *    * As always, remember that this podcast is brought to you by VQR and the Center for Media and Citizenship. Plus, we're a member of the TEEJ.FM podcast network.   AND... The music of CIRCLE OF WILLIS was composed and performed by Tom Stauffer, Gene Ruley and their band THE NEW DRAKES. You can purchase this music at their Amazon page. 

#ExpertAnswers - an InsideScientific Podcast
#ExpertAnswers: Erin Feser & Coleman Bessert on Kinesiological Electromyography

#ExpertAnswers - an InsideScientific Podcast

Play Episode Listen Later Nov 15, 2017 10:53


In this episode of Expert Answers, Erin Feser, MSc and Coleman Bessert answer questions about kinesiological EMG.

#ExpertAnswers - an InsideScientific Podcast
#ExpertAnswers: Erin Feser & Coleman Bessert on Kinesiological Electromyography

#ExpertAnswers - an InsideScientific Podcast

Play Episode Listen Later Nov 15, 2017 10:53


In this episode of Expert Answers, Erin Feser, MSc and Coleman Bessert answer questions about kinesiological EMG.

AANEM Presents Nerve and Muscle Junction
Optimizing Muscle Selection for Electromyography in Amyotrophic Lateral Sclerosis

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Jun 22, 2017 18:53


Optimizing Muscle Selection for Electromyography in Amyotrophic Lateral Sclerosis

AANEM Presents Nerve and Muscle Junction
Optimizing muscle selection for electromyography in amyotrophic lateral sclerosis

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Jun 22, 2017 18:53


Dr. Justin Willer interviews Dr. Yuebing Li about optimizing muscle selection for electromyography in amyotrophic lateral sclerosis. He was part of a group that compared the yield of limb and thoracic paraspinal muscle examination for revealing lower motor neuron (LMN) dysfunction on electromyography (EMG) in amyotrophic lateral sclerosis (ALS). Distal limb muscles showed the highest electrodiagnostic sensitivities of LMN dysfunction in ALS regardless of onset region and diagnostic certainty at the time of diagnosis. Electrodiagnostic yield is higher in muscles from the onset limb. Noncontiguous spread of lower motor neuron degeneration is present in ALS. Optimally selected 6 upper and 5 lower extremity muscles yielded >98% of potential positive cervical or lumbosacral segments. An algorithmic approach to needle EMG in ALS based on pretest probability of individual muscles optimizes electrodiagnostic yield, thus possibly minimizing test duration and patient discomfort. Muscle Nerve. 2016 Oct 19. doi: 10.1002/mus.25444.

AANEM Presents Nerve and Muscle Junction
Optimizing muscle selection for electromyography in amyotrophic lateral sclerosis

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Jun 22, 2017 18:53


Dr. Justin Willer interviews Dr. Yuebing Li about optimizing muscle selection for electromyography in amyotrophic lateral sclerosis. He was part of a group that compared the yield of limb and thoracic paraspinal muscle examination for revealing lower motor neuron (LMN) dysfunction on electromyography (EMG) in amyotrophic lateral sclerosis (ALS). Distal limb muscles showed the highest electrodiagnostic sensitivities of LMN dysfunction in ALS regardless of onset region and diagnostic certainty at the time of diagnosis. Electrodiagnostic yield is higher in muscles from the onset limb. Noncontiguous spread of lower motor neuron degeneration is present in ALS. Optimally selected 6 upper and 5 lower extremity muscles yielded >98% of potential positive cervical or lumbosacral segments. An algorithmic approach to needle EMG in ALS based on pretest probability of individual muscles optimizes electrodiagnostic yield, thus possibly minimizing test duration and patient discomfort. Muscle Nerve. 2016 Oct 19. doi: 10.1002/mus.25444.

BrainWaves: A Neurology Podcast
#40 Teaching through clinical cases: Wrist drop

BrainWaves: A Neurology Podcast

Play Episode Listen Later Dec 29, 2016 12:55


This week, I'm handing the mic over to Dr. Laura Mainardi so she can give us some pointers on the evaluation of hand weakness. We're thumbing through a few tips on working up wrist drop in particular. Hoping you give us two thumbs up on this one! ;-) BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision making in routine clinical practice. REFERENCES 1. Preston DC & Shapiro BE. Electromyography and neuromuscular disorders, 3rd ed. Saunders (2013).

BrainWaves: A Neurology Podcast

Quick tutorial to help you navigate through the causes of foot drop. Check it out! BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision making in routine clinical practice. Any cases discussed in this episode are fictional and do not contain any patient health identifying information. REFERENCES Preston DC & Shapiro BE. Electromyography and neuromuscular disorders, 3rd ed. Saunders (2013).

JAMA Otolaryngology–Head & Neck Surgery Author Interviews: Covering research, science, & clinical practice in diseases of t
Correlation of Final Evoked Potential Amplitudes on Intraoperative Electromyography of the Recurrent Laryngeal Nerve With Immediate Postoperative Vocal Fold Function After Thyroid and Parathyroid Surgery

JAMA Otolaryngology–Head & Neck Surgery Author Interviews: Covering research, science, & clinical practice in diseases of t

Play Episode Listen Later Jan 2, 2014 6:23


Interview with Ralph P. Tufano, MD, MBA, author of Correlation of Final Evoked Potential Amplitudes on Intraoperative Electromyography of the Recurrent Laryngeal Nerve With Immediate Postoperative Vocal Fold Function After Thyroid and Parathyroid Surgery

Medizin - Open Access LMU - Teil 20/22
Facioscapulohumeral muscular dystrophy and Charcot-Marie-Tooth neuropathy 1A-evidence for "double trouble" overlapping syndromes

Medizin - Open Access LMU - Teil 20/22

Play Episode Listen Later Jan 1, 2013


Background: We report on a patient with genetically confirmed overlapping diagnoses of CMT1A and FSHD. This case adds to the increasing number of unique patients presenting with atypical phenotypes, particularly in FSHD. Even if a mutation in one disease gene has been found, further genetic testing might be warranted in cases with unusual clinical presentation. Case presentation: The reported 53 years old male patient suffered from walking difficulties and foot deformities first noticed at age 20. Later on, he developed scapuloperoneal and truncal muscle weakness, along with atrophy of the intrinsic hand and foot muscles, pes cavus, claw toes and a distal symmetric hypoesthesia. Motor nerve conduction velocities were reduced to 20 m/s in the upper extremities, and not educible in the lower extremities, sensory nerve conduction velocities were not attainable. Electromyography showed both, myopathic and neurogenic changes. A muscle biopsy taken from the tibialis anterior muscle showed a mild myopathy with some neurogenic findings and hypertrophic type 1 fibers. Whole-body muscle MRI revealed severe changes in the lower leg muscles, tibialis anterior and gastrocnemius muscles were highly replaced by fatty tissue. Additionally, fatty degeneration of shoulder girdle and straight back muscles, and atrophy of dorsal upper leg muscles were seen. Taken together, the presenting features suggested both, a neuropathy and a myopathy. Patient's family history suggested an autosomal dominant inheritance. Molecular testing revealed both, a hereditary motor and sensory neuropathy type 1A (HMSN1A, also called Charcot-Marie-Tooth neuropathy 1A, CMT1A) due to a PMP22 gene duplication and facioscapulohumeral muscular dystrophy (FSHD) due to a partial deletion of the D4Z4 locus (19 kb). Conclusion: Molecular testing in hereditary neuromuscular disorders has led to the identification of an increasing number of atypical phenotypes. Nevertheless, finding the right diagnosis is crucial for the patient in order to obtain adequate medical care and appropriate genetic counseling, especially in the background of arising curative therapies.

AANEM Presents Nerve and Muscle Junction
Pediatric Electromyography by H. Royden Jones, MD

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Nov 5, 2008 46:39


An interview with H. Royden Jones, MD about Pediatric Electromyography. Interviewed by Edward Smith, MD and John Mytinger, MD.

AANEM Presents Nerve and Muscle Junction
Pediatric Electromyography by H. Royden Jones, MD

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Nov 5, 2008 46:39


An interview with H. Royden Jones, MD about Pediatric Electromyography. Interviewed by Edward Smith, MD and John Mytinger, MD.

AANEM Presents Nerve and Muscle Junction
Pediatric Electromyography

AANEM Presents Nerve and Muscle Junction

Play Episode Listen Later Nov 4, 2008 46:26


Pediatric Electromyography by H. Royden Jones, MD

Medizin - Open Access LMU - Teil 11/22
Penile Electromyography in the Diagnosis of Impotence

Medizin - Open Access LMU - Teil 11/22

Play Episode Listen Later Jan 1, 1994


Sat, 1 Jan 1994 12:00:00 +0100 https://epub.ub.uni-muenchen.de/10345/1/10345.pdf Keuppens, F.; Stief, Christian Georg; Bruyne, R. de; Schmedding, E.; Merckx, L. ddc:610, Medizin

Medizin - Open Access LMU - Teil 03/22
An autopsy study of a familial oculopharyngeal muscular dystrophy (OPMD) with distal spread and neurogenic involvement

Medizin - Open Access LMU - Teil 03/22

Play Episode Listen Later Jan 1, 1981


An 81-year-old man from a family with a history of oculopharyngeal muscular dystrophy (OPMD) involving 6 members over 4 generations is described. The patient first noted drooping of his eyelids at the age of 65. Dysphagia and dysarthria occurred soon thereafter. At age 78, impairment of gait developed and progressive wasting occurred in the limbs with an initial distal distribution. Electromyography of several limb muscles displayed a mixed myopathic and neurogenic pattern with giant potentials. Examination at autopsy revealed slight loss of neurons in the anterior horns of the spinal cord, with scanty ghost cells, neuronophagia, and central chromatolysis. By light microscopy the limb muscles showed moderate small-group atrophy with severe myopathy and target fibers. The viscerocranial muscles, including the ocular, vocal, and tongue muscles, demonstrated only myopathic change with the typical features of progressive muscular dystrophy. Advanced replacement by fibrous connective tissue and fat had occurred in both the viscerocranial and the lower limb muscles. The significance of neurogenic involvement in OPMD is discussed.