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*Fique bem-informado com as notícias do Programa Agronegócio Hoje de 02/06/2025*
Ever wonder what it takes to captivate an audience and deliver a winning speech? Join us in today's bonus episode, where we sit down with three of the recent past National winners of the JCI Effective Speaking Competition. We go beyond the podium to uncover the secrets of these exceptional orators.You'll hear from each champion, sharing their top three tips for crafting and delivering a speech that resonates. From conquering stage fright to mastering the art of storytelling, our guests provide practical advice you can use to elevate your own public speaking skills and possibly bring home the crown and glory for your Local Organization and Country.But it's not all about technique! We also delve into the personal journeys of these speakers, exploring their most cherished memories from the Effective Speaking Journey and how the experience shaped their lives. Get ready to be inspired, informed, and entertained as we celebrate the power of effective communication with JCI's finest.Connect with these CHAMPS below:Jonah Gowans: https://www.linkedin.com/in/jonah-gowans-a819a680/Laura Sankey: https://www.linkedin.com/in/laura-sankey-57112397/Danielle Hofer: https://www.linkedin.com/in/danielle-hofer/?originalSubdomain=ca
The NETwork continues the battle. Frey has a shocking revelation, Uther helps Malice find the humor in the situation, and Stynexx gets a sinking feeling about Johnson's survival.Find us on the The Actual Playce Discord ServerHit us up with any questions or comments:Insta @crittalkerspodcastFacebook: crittalkerspodcastX: @Crittalkerspodor drop us an emailthecast@crittalkerspodcast.comBritt H. Plays Frey the RogueShane F. plays “Sir” Uther the BardChris A. plays Stynexx the ArrificerMusic/Sound Effects Include:Recap voice acting by Jennifer Millard, written by Jake PrewittFrey is played by Britt H.Uther is played by Shane FStynexx is played by Chris A."Camera Flash" by MalarBrush"The Details Intro" by Ryan S."The Details Long" by Ryan S."Rest of The Fallen" by GuilhermeBernardes via Pixabay"Comedy - Detective" by Onoychenkomusic via Pixabay"Chamber Strings" by SigmaMusicArt via Pixabay"Dizzy ellectric bolt spell 1" by FxProSound via PixabayAdditional Royalty free Music and SFX Credits that were found via Pixabay: Dark Industrial by TazDev_musicCrossbow Firing by freesound_community"Robot Heavy Mechanical Footsteps" by DavidDumaisAudio Magic glitter wand 5 by FxProSoundAction Epic Cinematic Victory by Good_B_Musiccoughing man by oceaneyes91Static Electicity by SoundRealityCold and Coughing by FNX_SoundCoughing by freesound_communityShirt Clothing Movement by freesound_communityEnergy Sword by freesound_communityMagical Spell Cast by DavidDumaisAudioproximity by freesound_communityhitting the wall with a stick by freesound_communitySad by Music_For_VideosTense Suspense Background Music by HitsLabBreaking ice by freesound_communityWind blowing sfx by JCI-21
Not really sure what JCI Canada is all about? Neither was (now NVP) Stuart Knott when he stumbled into his first JCI Penticton meeting! Thankfully he found his feet quickly and seized the value-adds offered through JCI's focus on leveling up leadership skills, connecting with other driven young professionals, and making a real impact on one's community. In this podcast we talk about how all of these features can culminate in one's life PLUS, imagine the thrill of hosting a national JCI convention – a chance to showcase your city, build unforgettable experiences, and leave a lasting legacy-- in today's episode you'll hear some great advice on what to do to make for a successful event! GET YOUR 2025 JCI Penticton NAT CON Tickets here: https://www.jcipenticton.com/natcon2025
A new year, a new beginning and a new host. Welcome back to the JCI Canada Podcast and come along for the ride to dive deeper into the layer of JCI and what it can offer to you in both your personal and professional growth journey!
Episode kali ini menghadirkan Ronald Suryaputra bersama Risa Santoso, seorang senior trainer dan sekaligus juga seorang Rektor Institut Teknologi dan Bisnis Asia Malang. Sebagai salah satu rektor termuda di dunia, Risa berbagi perjalanan pendidikannya yang luar biasa, mulai dari meraih gelar sarjana ekonomi hingga menyelesaikan pendidikan magister di Harvard Graduate School of Education dengan beasiswa. Risa juga membahas penghargaan bergengsi Ten Outstanding Young Persons (TOYP) World yang diberikan oleh Junior Chamber International (JCI). Penghargaan ini sangat istimewa karena ia menjadi orang Indonesia pertama yang memenangkannya dalam 30 tahun terakhir. Risa berbagi cerita di balik proses nominasi, kontribusi sosialnya, dan bagaimana penghargaan ini mengakui dampaknya dalam dunia pendidikan. Sebagai seorang pemimpin muda, Risa mengajak generasi muda untuk mendokumentasikan prestasi mereka dan memanfaatkan peluang dari organisasi seperti JCI. Tidak hanya itu, Risa mengungkapkan visi besarnya untuk meningkatkan sistem pendidikan di Indonesia. Dari pengembangan kurikulum yang terintegrasi hingga fokus pada pengalaman belajar yang aplikatif, ia menunjukkan bagaimana pendidikan dapat menjadi jembatan menuju masa depan yang lebih baik.
On today's episode of HVAC TV, we continue the countdown of the 10 best podcasts of 2024. At number nine, I'm sharing one of my favorite podcasts, which I recorded with Jason Richwine with JCI, where he shows how selecting coils with a higher pressure drop can lead to higher efficiency in your system. I hope you enjoy it. Stay tuned for the next eight episodes on the countdown.
PALERMO (ITALPRESS) - Un ulteriore riconoscimento per la qualità dei percorsi di cura e assistenza, a corredo di un 2024 con numeri positivi: l'Ismett di Palermo ha ricevuto il sesto accreditamento dalla Joint Commission International, con il sopralluogo degli ispettori che è avvenuto pochi giorni fa. JCI è il principale ente di accreditamento in sanità a livello mondiale, e l'Istituto è stato il primo centro dell'Italia meridionale a essere accreditato.Barbara Ragonese, responsabile Qualità di Ismett, spiega che “la certificazione Jci è il risultato di un processo valutativo che viene condotto da esperti del settore sanitario, per valutare l'aderenza da parte dell'organizzazione a una serie di standard predefiniti che si basano su buone pratiche riconosciute a livello internazionale mirate a gestire problemi comuni a tutte le organizzazioni sanitarie. Gli ospedali che decidono di intraprendere il percorso per la certificazione Jci si impegnano a integrare queste buone pratiche nei propri processi e garantire la corretta applicazione delle procedure per la sicurezza del paziente in maniera sistematica e puntuale”.f15/xd8/fsc/gtr
PALERMO (ITALPRESS) - Un ulteriore riconoscimento per la qualità dei percorsi di cura e assistenza, a corredo di un 2024 con numeri positivi: l'Ismett di Palermo ha ricevuto il sesto accreditamento dalla Joint Commission International, con il sopralluogo degli ispettori che è avvenuto pochi giorni fa. JCI è il principale ente di accreditamento in sanità a livello mondiale, e l'Istituto è stato il primo centro dell'Italia meridionale a essere accreditato.Barbara Ragonese, responsabile Qualità di Ismett, spiega che “la certificazione Jci è il risultato di un processo valutativo che viene condotto da esperti del settore sanitario, per valutare l'aderenza da parte dell'organizzazione a una serie di standard predefiniti che si basano su buone pratiche riconosciute a livello internazionale mirate a gestire problemi comuni a tutte le organizzazioni sanitarie. Gli ospedali che decidono di intraprendere il percorso per la certificazione Jci si impegnano a integrare queste buone pratiche nei propri processi e garantire la corretta applicazione delle procedure per la sicurezza del paziente in maniera sistematica e puntuale”.f15/xd8/fsc/gtr
PALERMO (ITALPRESS) - Un ulteriore riconoscimento per la qualità dei percorsi di cura e assistenza, a corredo di un 2024 con numeri positivi: l'Ismett di Palermo ha ricevuto il sesto accreditamento dalla Joint Commission International, con il sopralluogo degli ispettori che è avvenuto pochi giorni fa. JCI è il principale ente di accreditamento in sanità a livello mondiale, e l'Istituto è stato il primo centro dell'Italia meridionale a essere accreditato.Barbara Ragonese, responsabile Qualità di Ismett, spiega che “la certificazione Jci è il risultato di un processo valutativo che viene condotto da esperti del settore sanitario, per valutare l'aderenza da parte dell'organizzazione a una serie di standard predefiniti che si basano su buone pratiche riconosciute a livello internazionale mirate a gestire problemi comuni a tutte le organizzazioni sanitarie. Gli ospedali che decidono di intraprendere il percorso per la certificazione Jci si impegnano a integrare queste buone pratiche nei propri processi e garantire la corretta applicazione delle procedure per la sicurezza del paziente in maniera sistematica e puntuale”.f15/xd8/fsc/gtr
The NETwork continues their investigation, talk to the voice in their head, got a glowup and they're ready to slay. Frey collects a specimen, Uther protects the crime scene's integrity and Stynexx discovers a new friend.Hit us up with any questions or comments:Insta @crittalkerspodcastFacebook: crittalkerspodcastX: @Crittalkerspodor drop us an emailthecast@crittalkerspodcast.comMusic/Sound Effects Include:Recap voice acting by Jennifer Millard, written by Jake Prewitt"Camera Flash" by MalarBrush"The Details Intro" by Ryan S."The Details Long" by Ryan S."Rest of The Fallen" by GuilhermeBernardes via Pixabay"Comedy - Detective" by Onoychenkomusic via Pixabay"Chamber Strings" by SigmaMusicArt via Pixabay"Dizzy ellectric bolt spell 1" by FxProSound via PixabayOpening cut scene co-written by Jake the GM, Shane F. and Chris A. Voice Acting Performed by Jake the GM"Level up" by Ryan S."Ponerman" by Ryan S.Lyria's Journal entries written by Jake the GM. Voice Acting by Jennifer Millard."Hidden Depth (Dark Epic Crime Gothic Underground Hip Hop Beat Music)" by AUDIOREZOUT via Pixabay "creaking-wood-screws" by freesound_community via Pixabay"Ponerman" by Ryan S."Walk Alone | Dark Cinematic Music | Horror Music" by MusiQO via Pixabay"Engineers" by agerabeatz via Pixabay"Blip 5" by freesound_community via Pixabay"Main Door Opening-Closing" by freesound_community via Pixabay"Wooden Door Slamming Close" by freesound_community via Pixabay"Glass Shatter 3" by freesound_community via Pixabay"Dark Ambient Horror Cinematic Halloween Atmosphere Scary" by SoundGalleryByDmitryTaras via Pixabay"Dropping a Pen on Wood" by freesound_community via Pixabay"Horror Dark Piano" by leberchmus via Pixabay"Heartbeat 02" by BRVHRTZ via Pixabay"Shower in Bathroom" by freesound_community via Pixabay"shower curtain fast" by freesound_community via Pixabay"Dances with Kittens" by GoldenSoundLabs via Pixabay"Sneaking In the Dark, Track by, Brolefilmer" by brolefilmer via Pixabay"My Cat is Crazy" by geoffharvey via Pixabay"Shaking Coins (No Effects)" by freesound_community via Pixabay"Wooden Trunk Latch 2" by floraphonic via Pixabay"Robot Heavy Mechanical Footsteps" by DavidDumaisAudio via Pixabay"Robot" by freesound_community via Pixabay"Knife being sharpened" by freesound_community via Pixabay"energy hum" by freesound_community via Pixabay"Toxic Scydust (Dark Sci-Fi Future Ambient Space Cinematic Trailer)" by AUDIOREZOUT via Pixabay"Dark Fear (Epic Crime Gothic Underground Hip Hop Beat Music)" by AUDIOREZOUT via Pixabay"Industrial Ambience" by Alex_Jauk via Pixabay"Lifeforce Combustion" by freesound_community via Pixabay"Wierd buzz (img2snd)" by freesound_community via Pixabay"Male Extreme Scream" by Universfield via Pixabay"Wooden Chair Move" by freesound_community via Pixabay"Bottle hitting a table" by freesound_community via Pixabay"Wind blowing" sfx by JCI-21 via Pixabay"Click Button" by Universfield via Pixabay"Buzz Buzz" by freesound_community via Pixabay
The Filtrate:Joel TopfSwapnil HiremathWith Special Guest:Michelle Hladunewich, Nephrologist at the University of TorontoMir Melamed, Maternal-Fetal Medicine at the University of TorontoEditor Simon TopfShow NotesPriscilla Smith's letter:Dear Joel and the Freely Filtered team,I am a long-time fan of your podcast and was looking forward to hearing your recently aired discussion of the Praecis study of sflt1:PlGF use in preeclampsia. Preeclampsia and renal disease in pregnancy are areas that many nephrologists report a lack of knowledge or confidence in discussing and managing. I am a nephrologist who has been co-leading a renal pregnancy clinic in London while writing a PhD on progression of renal disease in pregnancy. I have had the immense privilege of working with experts and key opinion leaders in preeclampsia research both in the UK and internationally. As you know, preeclampsia is a serious and significant condition contributing to global maternal mortality and is also associated with future CKD and CVD risk so is both relevant and important within our professional group.Sadly, I found myself disappointed by the episode and felt it was a missed opportunity. I appreciate that you had difficulties obtaining appropriate experts to join the discussion, but perhaps it would have been better to delay production. While you all valiantly proceeded to discuss this important study, the topic is complex and there appeared to be a lack of understanding of the surrounding literature and pathogenesis of preeclampsia. Sadly, the maternal medicine expert's comments at the end of the podcast added little as she seemed determine to negate any benefit from the results despite declaring she had no experience or expertise in the use of these biomarkers.There are many people who understand the clinical aspects of preeclampsia as well as having direct experience of the use and utility of these biomarkers who would have been able to contribute much to your conversation. I look forward to future discussions of renal disease in pregnancy on your podcast and would be happy to suggest some expert panellists if you ever find yourself stuck.Kind regards,Priscilla Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia (JCI 2003)sFlt background: Pathogenesis of Preeclampsia and Therapeutic Approaches Targeting the Placenta (PubMed)PlGF background: Perspectives on the Use of Placental Growth Factor (PlGF) in the Prediction and Diagnosis of Pre-Eclampsia: Recent Insights and Future Steps (PubMed)The PRAECIS trial (NephJC | NEJM Evidence)
In this episode, we dive into how AI is transforming leadership development, project management, membership recruitment, and more. Join us as we explore the exciting ways AI is reshaping these areas and driving innovation. Question to listeners! How can we use AI to enhance leadership development opportunities within JCI?
Is there a right surgical approach that completely transforms the lives of patients with myocardial bridges? This episode is a live recording of the first ever myocardial bridge meetup where Dr. Theo Kofidis, took the time to virtually join us from Greece for the first session of the day. We learned of his ambitious project of revamping a JCI accredited hospital into a cutting-edge medical facility. He takes questions from the group including attendee Jane's prolonged struggle with myocardial bridge symptoms and provides suggestions and support from his perspective. He shares insights into the significance of timely intervention and the crucial consideration of surgical options when medication fails. Questions from the group included best practices for unroofing a myocardial bridge. Dr. Kofidis outlines the meticulous surgical techniques that ensure optimal outcomes in his opinion. We dig deeper into the importance of global collaboration among healthcare professionals to enhance treatment efficacy and work toward identifying long term, symptom free patients to better support proper procedures for "unroofing". We spoke of advanced diagnostic tools like 3D reconstruction and high-frequency ultrasound that aid in post-operative evaluation, and heard why minimally invasive endoscopic approaches, complemented by tactile feedback, offer significant benefits. The group got expert advice on achieving comprehensive and precise surgical results for myocardial bridges that we're now sharing with anyone interested. Finally, we ventured into the realm of advanced diagnostics and the role of AI in cardiology. Dr. Kofidis discussed the underdiagnosed prevalence of myocardial bridges and their connection to coronary artery disease and coronary artery spasms. We conclude with an engaging discussion on medical tourism in Greece, highlighting its potential advantages and the robust support system within the medical community. Dr. Kofidis, as always, offers his expert advice and invites any concerned or interested party to reach out for a discovery call to see if Greece might be an option for you. What a special treat it was indeed. You cab reach Dr. Kofidis by email: tkofidis@hotmail.de Episode Chapter Summaries (00:00) Myocardial Bridge Treatment and ComplicationsDr. Kofidis discusses his transition to a new hospital, upcoming operations on myocardial bridge patients, and the importance of prompt treatment and medical options. (14:59) Optimal Methods for Myocardial Bridge UnroofingNature's intricacies of unroofing a myocardial bridge, collaboration between surgeons and cardiologists, and use of advanced diagnostic tools. (22:49) International Heart Surgery Center in AthensCT scanning technology and AI in cardiology improve accurate diagnosis of myocardial bridges and their relationship with coronary artery disease. (35:43) Heart Surgery Tourism ConversationDr. Kofidis and I discuss the pleasure of visiting Greece, medical tourism, and the supportive network within the medical community.
Je suis très heureuse d'accueillir Damien BAPTISTE, coach et mentor pour nous parler masculinité et nouveau paradigme. Pour moi, Damien incarne parfaitement l'équilibre des énergies féminines et masculines et avance en pionnier. Il a accepté, avec alignement et intégrité, de répondre à toutes mes questions et avons échangé sur l'évolution et la place des hommes du nouveau paradigme qui souhaitent se réaliser en 2024. Diplômé d'un master en conseil en management ses talents et son goût pour le leadership l'ont amené à devenir chef de projet sur 2 projets ambitieux : un extranet de gestion des formations pour une administration territoriale et la mise en production des plateformes de paiement européen pour une banque, puis officie en tant que consultant en financement de la R&D. Il officie ensuite comme manager d'une équipe de 6 personnes, générant 2,5 millions de CA et ayant un portefeuille de comptes clés comme IBM, IDEMIA ou encore OVH. Engagé, il est membre de la Jeune Chambre Internationale (JCI) pendant 12 ans. Il est élu président de la JCE de Lyon puis de la fédération avant de devenir membre du conseil d'administration de la Jeune Chambre Economique française. Durant son mandat, il expérimente et essaime avec les 130 organisations locales le CV citoyen qui impactera en une seule année 5000 jeunes et 500 entreprises. Il devient sénateur et membre à vie de la JCI. ✨✨✨Curieux et ouvert, il s'intéresse aux cultures des peuples premiers (Maasaï, Kogis, Lakota) et leur spiritualité. Il se penche sur différentes philosophies : le Taoïsme et le Confucianisme. Il découvre, alors, de nouvelles manières de s'éveiller à sa pleine maturité et d'atteindre ses objectifs en participant régulièrement à des retraites, des méditations, des programmes de leadership et d'intelligence émotionnelle. Il pratique également le DO-IN et le Taï Chi Chuan. Passionné par l'évolution humaine et les collectifs, ces différentes expériences l'ont incité à se former et certifier au coaching pour accompagner les femmes et les hommes, à responsabilité, à révéler leurs potentiels et développer leur prospérité. En 2022, il fonde MANKIUS, son cabinet de conseil spécialisé dans le leadership et la cohésion de groupe et créé le parcours MOMENTUM.Sa vision : « Devenir le premier acteur de l'évolution durable des êtres humains et des organisations ». Sa mission : « Accompagner chacun à révéler pleinement ses talents et son unicité ». *Retrouver le Plaisir de Vivre Chaque Jour *Reconnecter Cœur et Esprit : Agir avec Puissance *Comprendre ses Valeurs pour Évoluer: Clé du Succès *Développer son Équilibre Masculin et Féminin en 2024 *L'Homme et l'Écosystème: Vers un Soutien Renouvelé *Libérez Votre Potentiel: L'Association Ciel-Terre *Réaliser ses rêves à tous les âges: C'est Possible! *PMA et Masculinité : Réflexions Profondes sur la Fertilité *Changez de Job: Comment Planifier votre Avenir Professionnel *L'Importance de la Pacification Intérieure pour un Nouveau Paradigme *Coaching Écoute Active : Nouvel Masculin *Redéfinir la Masculinité *Le Vrai Bonheur : Au-Delà des Objectifs *Retrouver le Sens: Réinventer sa Vision Professionnelle *Réapprendre à s'aimer : Un voyage intérieur inspirant *Équilibre Féminin et Masculin : Clé du Couple Épanoui *Révéler le Pouvoir des Pionniers : Construire Ensemble *Reconnectez-vous à votre Essence: Énergie et Pragmatisme Pour découvrir Damien, https://www.mankius.com/ Je vous souhaite une belle écoute
Welcome to the JCI Canada Podcast, where today, as we celebrate Canada Day, we have a special episode lined up just for you. Join us as we sit down with the National President of JCI Canada, Jasper Salinana, to uncover his strategic vision for the year ahead. From empowering communities to the essentials of starting your own JCI Chapter, this episode is packed with insights and inspiration. Whether you're a seasoned member or new to the JCI community, get ready to be motivated and informed. #JCICanada #CanadaDay #Leadership #CommunityService #YouthEmpowerment --- Send in a voice message: https://podcasters.spotify.com/pod/show/jci-canada0/message
How to Trade Stocks and Options Podcast by 10minutestocktrader.com
Join us in this week's trading review as we highlight some remarkable wins! Discover how an impressive 89% gain was achieved with JCI calls and how a 27% overnight profit was secured with Ford options. Additionally, learn about a strategy for consistent 7% weekly returns using Virgin Galactic covered calls. Stay tuned for detailed breakdowns and insights into these successful trades. #Trading #Stocks #JCI #Ford #VirginGalactic #OptionsTrading #CoveredCalls #Profit #StockMarket #Investing #OutlierTrading #WeeklyWinners #TradingStrategies #FinancialSuccess
In this episode, Xavier Bonilla has a dialogue with Ajit Varki about the evolutionary origins of denial and self-deception. They discuss the evolutionary perspective of human origins, self-awareness in humans, theory of mind, and how false beliefs and denial evolved. They also discuss lying, self-deception, religion, positive uses of deception, climate change, future of Mind Over Reality theory, and many more topics. Ajit Varki received training in physiology, medicine, biology, and biochemistry at the Christian Medical College, Vellore, The University of Nebraska, Omaha, and Washington University, St. Louis. He was trained and board-certified in internal medicine, hematology, and oncology. He joined the faculty of the University of California, San Diego (UCSD) in 1982.Dr. Varki is an elected member of the American Academy of Arts & Sciences, National Academy of Medicine, American Society for Clinical Investigation, Association of American Physicians, and of Sigma Xi. He has been a recipient of a MERIT award from the NIH, the American Cancer Society Faculty Research Award, as well as three of the highest honors in the field: the Karl Meyer Award (2005), the International Glycoconjugate Organization Award (2007), the Rosalind Kornfeld Award for Lifetime Achievement in Glycobiology (2020), and the ASBMB Herbert Tabor Research Award (2023). He was also elected President of the American Society for Clinical Investigation (1998–1999), President of the Society for Glycobiology (1996) and served Editor-In-Chief of the Journal of Clinical Investigation (1992–1997). He is recognized for creating the first major open access research journal, The Journal of Clinical Investigation, JCI (1996), as well as the first major open access textbook, Essentials of Glycobiology (2008). Dr. Varki was honored with the Old Cottonian of Eminence Award at the 150th Anniversary of Bishop Cotton Boy's School in Bangalore, India (2015) and he was also honored with the Annual Research Day Distinguished Faculty Medal and Oration at his medical school alma mater, the Christian Medical College, Vellore, India (2020). Dr. Varki's interests in human evolution also led him to propose a novel Mind Over Reality Transition theory about human origins, in the book, Denial. Get full access to Converging Dialogues at convergingdialogues.substack.com/subscribe
We kick things off today with a focus on a lackluster performance on Wall Street as investors become more and more anxious about the impending inflation report due out tomorrow. For the interview we'll be talking to real estate associate broker Wayde Burkhart about the housing industry and then take a deep dive into the history of the United States Junior Chamber of Commerce now known at JCI. Wayde is helping oversee a six state regional meeting of JCI Senators who will converge on Des Moines April 19 - 21. And, yes, we name...names. Also if you want to reach us on social media and if you're on Threads you can find us @Insight_On_Business. And you can hook up with us all day on Twitter or "X" @IOB_NewsHour and on Instagram. Facebook? Sure were there too. Here's what we've got for you today: Investors are spooked about the upcoming inflation report; Laid off workers are finding a new career in creating...content; A big time for theater owners in Las Vegas and what they are saying; Get ready another price jump for first class letters; Tesla stock continues to slide. Will the company recover? The Wall Street Report; And, which states have the most million dollar homes? For the interview you'll hear from my old friend Wayde Burkhart who is not only a realtor (and we do talk about the market) but also a JCI Senator #63877. We're talking about some Junior Chamber of Commerce memories and about an upcoming event being held in Des Moines April 19 - 21. It's a fun walk down memory land and to listen to our conversation click THIS LINK. Thanks for listening! The award winning Insight on Business the News Hour with Michael Libbie is the only weekday business news podcast in the Midwest. The national, regional and some local business news along with long-form business interviews can be heard Monday - Friday. You can subscribe on PlayerFM, Podbean, iTunes, Spotify, Stitcher or TuneIn Radio. And you can catch The Business News Hour Week in Review each Sunday Noon Central on News/Talk 1540 KXEL. The Business News Hour is a production of Insight Advertising, Marketing & Communications. You can follow us on Twitter @IoB_NewsHour...and on Threads @Insight_On_Business.
Jason Jimenez-Vanover and Joe Lynch discuss AI driven sales & marketing. Jason is the CEO and Founder of JCI Marketing, a freight-focused content marketing agency that specializes in working with transportation, logistics and supply chain companies. About Jason Jimenez-Vanover Jason Jimenez-Vanover is the CEO and Founder of JCI Marketing, a freight-focused marketing agency. With more than a decade of experience in marketing for the supply chain, Jason built his career on content creation as a copywriter and marketing consultant. His expertise stretches across the logistics universe, working with brands from the Top 100 Logistics Providers and many brokers. He also is a HubSpot Inbound Certified and Semrush Certified expert in content marketing. His passions include maintaining big-picture ideas for content, developing the iconic JC-AI, a solution that aims to create effective SaaS-based marketing, and continuously identifying new options for branding. About JCI Marketing JCI Marketing is a freight-focused content agency that specializes in working with those in the transportation, logistics and supply chain industries. Forging a trident of of white-glove service, first-hand knowledge and data-driven strategy, the JCI team is continuously looking for ways to augment brand value, awareness, and market share and has now built the JC-AI, an AI tool built for the specific purpose of creating high-quality content without the endless array of prompts and chatbots. JCI Marketing originated as a freelancing business more than a decade ago that grew into something more, and it's based on the founder, Jason Jimenez-Vanover's personal expertise in logistics and supply chain management, combined with a deep love of content creation. JCI Marketing services include building high-quality SEO strategies, social media management, and overall content creation. Key Takeaways: AI Driven Sales & Marketing JCI Marketing customers gain the following advantages: Specialization: They focus on content creation for the transportation, logistics, and supply chain industries. Approach: JCI Marketing combines personalized service, industry knowledge, and data-driven strategies to boost client brands. Services: They offer content creation (including SEO-focused content), social media management, and high-quality content creation tools (JC-AI). Experience: Founded on the expertise and passion of Jason Jimenez-Vanover, JCI Marketing has grown from a freelance business to a full-fledged agency. Process: JCI Marketing starts with a detailed audit of your online presence and brand goals. Onboarding: Their onboarding process goes beyond paperwork, involving in-depth interviews to fully understand your brand. Content Strategy: JCI Marketing tailors content goals based on your chosen services, focusing on maximizing impact and engagement. Learn More About AI Driven Sales & Marketing Jason Jimenez-Vanover | Linkedin JCI MArketing | Linkedin JCI Marketing The JC-AI Membership | JCI Marketing Contact JCI Marketing The Logistics of Logistics Podcast If you enjoy the podcast, please leave a positive review, subscribe, and share it with your friends and colleagues. The Logistics of Logistics Podcast: Google, Apple, Castbox, Spotify, Stitcher, PlayerFM, Tunein, Podbean, Owltail, Libsyn, Overcast Check out The Logistics of Logistics on Youtube
HOST: MARK LONGO, THE OPTIONS INSIDER MEDIA GROUP CO-HOST: ANDREW GIOVINAZZI, THE OPTION PIT CO-HOST: MIKE TOSAW, ST. CHARLES WEALTH MANAGEMENT CO-HOST: HENRY SCHWARTZ, CBOE GLOBAL MARKETS ON THIS EPISODE, MARK, THE ROCK LOBSTER, UNCLE MIKE, AND THE FLOWMASTER BREAK DOWN: THE LATEST IN THE OPTIONS MARKETS INCL VIX THE MOST ACTIVE EQUITY OPTIONS TODAY INCL TSLA UNUSUAL OPTIONS ACTIVITY IN CVE, JCI, SOUN WHAT'S ON OUR RADAR FOR THE REST OF THE WEEK AND WEEKEND AND MUCH MORE TRADE OF THE DAY INSIGHTS NEWSLETTER - REQUEST ACCESS TO ADMIN@TRADE-ALERT.COM
HOST: MARK LONGO, THE OPTIONS INSIDER MEDIA GROUP CO-HOST: ANDREW GIOVINAZZI, THE OPTION PIT CO-HOST: MIKE TOSAW, ST. CHARLES WEALTH MANAGEMENT CO-HOST: HENRY SCHWARTZ, CBOE GLOBAL MARKETS ON THIS EPISODE, MARK, THE ROCK LOBSTER, UNCLE MIKE, AND THE FLOWMASTER BREAK DOWN: THE LATEST IN THE OPTIONS MARKETS INCL VIX THE MOST ACTIVE EQUITY OPTIONS TODAY INCL TSLA UNUSUAL OPTIONS ACTIVITY IN CVE, JCI, SOUN WHAT'S ON OUR RADAR FOR THE REST OF THE WEEK AND WEEKEND AND MUCH MORE TRADE OF THE DAY INSIGHTS NEWSLETTER - REQUEST ACCESS TO ADMIN@TRADE-ALERT.COM
OutlineChapter 14- Hypovolemic States- Etiology - True volume depletion occurs when fluid is lost from from the extracellular fluid at a rate exceeding intake - Can come the GI tract - Lungs - Urine - Sequestration in the body in a “third space” that is not in equilibrium with the extracellular fluid. - When losses occur two responses ameliorate them - Our intake of Na and fluid is way above basal needs - This is not the case with anorexia or vomiting - The kidney responds by minimizing further urinary losses - This adaptive response is why diuretics do not cause progressive volume depletion - Initial volume loss stimulates RAAS, and possibly other compensatory mechanisms, resulting increased proximal and collecting tubule Na reabsorption. - This balances the diuretic effect resulting in a new steady state in 1-2weeks - New steady state means Na in = Na out - GI Losses - Stomach, pancreas, GB, and intestines secretes 3-6 liters a day. - Almost all is reabsorbed with only loss of 100-200 ml in stool a day - Volume depletion can result from surgical drainage or failure of reabsorption - Acid base disturbances with GI losses - Stomach losses cause metabolic alkalosis - Intestinal, pancreatic and biliary secretions are alkalotic so losing them causes metabolic acidosis - Fistulas, laxative abuse, diarrhea, ostomies, tube drainage - High content of potassium so associated with hypokalemia - [This is a mistake for stomach losses] - Bleeding from the GI tract can also cause volume depletion - No electrolyte disorders from this unless lactic acidosis - Renal losses - 130-180 liters filtered every day - 98-99% reabsorbed - Urine output of 1-2 liters - A small 1-2% decrease in reabsorption can lead to 2-4 liter increase in Na and Water excretion - 4 liters of urine output is the goal of therapeutic diuresis which means a reduction of fluid reabsorption of only 2% - Diuretics - Osmotic diuretics - Severe hyperglycemia can contribute to a fluid deficit of 8-10 Iiters - CKD with GFR < 25 are poor Na conservers - Obligate sodium losses of 10 to 40 mEq/day - Normal people can reduce obligate Na losses down to 5 mEq/day - Usually not a problem because most people eat way more than 10-40 mEq of Na a day. - Salt wasting nephropathies - Water losses of 2 liters a day - 100 mEq of Na a day - Tubular and interstitial diseases - Medullary cystic kidney - Mechanism - Increased urea can be an osmotic diuretic - Damage to tubular epithelium can make it aldo resistant - Inability to shut off natriuretic hormone (ANP?) - The decreased nephro number means they need to be able to decrease sodium reabsorption per nephron. This may not be able to be shut down acutely. - Experiment, salt wasters can stay in balance if sodium intake is slowly decreased. (Think weeks) - Talks about post obstruction diuresis - Says it is usually appropriate rather than inappropriate physiology. - Usually catch up solute and water clearance after releasing obstruction - Recommends 50-75/hr of half normal saline - Talks briefly about DI - Skin and respiratory losses - 700-1000 ml of water lost daily by evaporation, insensible losses (not sweat) - Can rise to 1-2 liters per hour in dry hot climate - 30-50 mEq/L Na - Thirst is primary compensation for this - Sweat sodium losses can result in hypovolemia - Burns and exudative skin losses changes the nature of fluid losses resulting in fluid losses more similar to plasma with a variable amount of protein - Bronchorrhea - Sequestration into a third space - Volume Deficiency produced by the loss of interstitial and intravascular fluid into a third space that is not in equilibrium with the extracellular fluid. - Hip fracture 1500-2000 into tissues adjacent to fxr - Intestinal obstruction, severe pancreatitis, crush injury, bleeding, peritonitis, obstruction of a major venous system - Difference between 3rd space and cirrhosis ascities - Rate of accumulation, if the rate is slow enough there is time for renal sodium and water compensation to maintain balance. - So cirrhotics get edema from salt retension and do not act as hypovolemia - Hemodynamic response to volume depletion - Initial volume deficit reduced venous return to heart - Detected by cardiopulmonary receptors in atria and pulmonary veins leading to sympathetic vasoconstriction in skin and skeletal muscle. - More marked depletion will result in decreased cardiac output and decrease in BP - This drop in BP is now detected by carotid and aortic arch baroreceptors resulting in splanchnic and renal circulation vasoconstriction - This maintains cardiac and cerebral circulation - Returns BP toward normal - Increase in BP due to increased venous return - Increased cardiac contractility and heart rate - Increased vascular resistance - Sympathetic tone - Renin leading to Ang2 - These can compensate for 500 ml of blood loss (10%) - Unless there is autonomic dysfunction - With 16-25% loss this will not compensate for BP when patient upright - Postural dizziness - Symptoms - Three sets of symptoms can occur in hypovolemic patients - Those related to the manner in which the fluid loss occurs - Vomiting - Diarrhea - Polyuria - Those due to volume depletion - Those due to the electrode and acid base disorders that can accompany volume depletion - The symptoms of volume depletion are primarily related to the decrease in tissue perfusion - Early symptoms - Lassitude - Fatiguability - Thirst - Muscle cramps - Postural dizziness - As it gets more severe - Abdominal pain - Chest pain - Lethargy - Confusion - Symptomatic hypovolemia is most common with isosmotic Na and water depletion - In contrast pure water loss, causes hypernatremia, which results in movement of water from the intracellular compartment to the extracellular compartment, so that 2/3s of volume loss comes from the intracellular compartment, which minimizes the decrease in perfusion - Electrolyte disorders and symptoms - Muscle weakness from hypokalemia - Polyuria/poly dips is from hyperglycemia and hypokalemia - Lethargy, confusion, Seizures, coma from hyponatremia, hypernatremia, hyperglycemia - Extreme salt craving is unique to adrenal insufficiency - Eating salt off hands ref 18 - Evaluation of the hypovolemic patient - Know that if the losses are insensible then the sodium should rise - Volume depletion refers to extracellular volume depletion of any cause, while dehydration refers to the presence of hypernatremia due to pure water loss. Such patients are also hypovolemic. - Physical exam is insensitive and nonspecific - Finding most sensitive and specific finding for bleeding is postural changes in blood pressure - I don't find this very specific at all! - Recommends laboratory confirmation regardless of physical exam - Skin and mucous membranes - Should return too shape quickly - Elastic property is called Turgur - Not reliable is patients older than 55 to 60 - Dry axilla - Dry mucus membranes - Dark skin in Addison's disease Frim increased ACTH - Arterial BP - As volume goes down so does arterial BP - Marked fluid loss leads to quiet korotkoff signs - Interpret BP in terms of the patients “normal BP” - Venous pressure - Best done by looking at the JVP - Right atrial and left atrial pressure - LV EDP is RAP + 5 mmHg - Be careful if valvular disease, right heart failure, cor pulmonare, - Figure 14-2 - Shock - 30% blood loss - Lab Data - Urine Na concentration - Should be less than 25 mmol/L, can go as low as 1 mmol/L - Metabolic alkalosis can throw this off - Look to the urine chloride - Figure 14-3 - Renal artery stenosis can throw this off - FENa - Mentions that it doesn't work so well at high GFR - Urine osmolality - Indicates ADH - Volume depletion often associated with urine osm > 450 - Impaired by - Renal disease - Osmotic diuretic - Diuretics - DI - Mentions that severe volume depletion and hypokalemia impairs urea retension in renal medulla - Points out that isotonic urine does not rule out hypovolemia - Mentions specific gravity - BUN and Cr concentration - Normal ratio is 10:1 - Volume depletion this goes to 20:1 - Serum Na - Talks about diarrhea - Difference between secretory diarrhea which is isotonic and just causes hypovolemia - And osmotic which results in a lower electrolyte content and development of hypernatremia - Talks about hyperglycemia - Also can cause the sodium to rise from the low electrolyte content of the urine - But the pseudohyponatraemia can protect against this - Plasma potassium - Treatment - Both oral and IV treatment can be used for volume replacement - The goal of therapy are to restore normovolemia - And to correct associated acid-base and electrolyte disorders - Oral Therapy - Usually can be accomplished with increased water and dietary sodium - May use salt tablets - Glucose often added to resuscitation fluids - Provides calories - Promotes intestinal Na reabsorption since there is coupled Na and Glucose similar to that seen in the proximal tubule - Rice based solutions provide more calories and amino acids which also promote sodium reabsorption - 80g/L of glucose with rice vs 20 g/L with glucose alone - IV therapy - Dextrose solutions - Physiologically equivalent to water - For correcting hypernatremia - For covering insensible losses - Watch for hyperglycemia - Footnote warns against giving sterile water - Saline solutions - Most hypovolemic patients have a water and a sodium deficit - Isotonic saline has a Na concentration of 154, similar to that of plasma see page 000 - Half-isotonic saline is equivalent to 550 ml of isotonic saline and 500 of free water. Is that a typo? - 3% is a liter of hypertonic saline and 359 extra mEq of Na - Dextrose in saline solutions - Give a small amount of calories, otherwise useless - Alkalinizing solutions - 7.5% NaHCO3 in 50 ml ampules 44 mEq of Na and 44 mEq of HCO3 - Treat metabolic acidosis or hyperkalemia - Why 44 mEq and not 50? - Do not give with calcium will form insoluble CaCO3 - Polyionic solutions - Ringers contains physiologic K and Ca - Lactated Ringers adds 28 mEq of lactate - Spreads myth of LR in lactic acidosis - Potassium chloride - Available as 2 mEq/mL - Do not give as a bolus as it can cause fatal hyperkalemia - Plasma volume expanders - Albumin, polygelastins, hetastarch are restricted to vascular space - 25% albumin can pull fluid into the vascular space - 25% albumin is an albumin concentration of 25 g/dL compare to physiologic 4 g/dL - Says it pulls in several times its own volume - 5% albumin is like giving plasma - Blood - Which fluid? - Look at osmolality, give hypotonic fluids to people with high osmolality - Must include all electrolytes - Example of adding 77 mEw of K to 0.45 NS and making it isotonic - DI can be replaced with dextrose solutions, pure water deficit - Case 14-3 - Diarrhea with metabolic acidosis - He chooses 0.25 NS with 44 mEq of NaCl and 44 NaHCO3 - Talks about blood and trauma - Some studies advocate delaying saline until penetrating trauma is corrected APR about to. Keep BP low to prevent bleeding. Worry about diluting coagulation factors - Only do this if the OR is quickly available - Volume deficit - Provides formula for water deficit and sodium deficit - Do not work for isotonic losses - Provides a table to adjust fluid loss based on changes in Hgb or HCTZ - Says difficult to estimate it from lab findings and calculations - Follow serial exams - Serial urine Na - Rate of replacement - Goal is not to give fluid but to induce a positive balance - Suggests 50-100 ml/hr over what is coming out of the body - Urine - Insensibles 30-50 - Diarrhea - Tubes - Hypovolemic shock - Due to bleeding - Sequesting in third space - Why shock? - Progressive volume depletion leads to - Increased sympathetic NS - Increased Ang 2 - Initially this maintains BP, cerebral and coronary circulation - But this can decrease splanchnic, renal and mucocutaneous perfusion - This leads to lactic acicosis - This can result in intracellular contents moving into circulation or translocation of gut bacteria - Early therapy to prevent irreversible shock - In dogs need to treat with in 2 hours - In humans may need more than 4 hours - Irreversible shock associated with pooling of blood in capillaries - Vasomotor paralysis - Hyperpolarization of vascular smooth muscle as depletion of ATP allows K to flowing out from K channels opening. Ca flows out too leading to vasodilation - Glyburide is an K-ATP channel inhibitor (?) caused increased vasoconstriction and BP - Pluggin of capillaries by neutrophils - Cerebral ischemia - Increased NO generation - Which Fluids? - Think of what is lost and replace that. - Bleeding think blood - Raise the hct but not above 35 - Acellular blood substitutes, looked bad at the time of this writing - Di aspirin cross linked hemoglobin had increased 2 and 28 day mortality vs saline - Colloids sound great but they fail in RCTs - SAFE - FEAST - Points out that saline replaces the interstitial losses why do we think those losses are unimportant - Pulmonary circulation issue - Pulmonary circulation is more leaky so oncotic pressure less effective there - Talks about the lungs be naturally protected from pulmonary edema - Rate of fluid - 1-2 liters in first hour - Suggests CVP or capillary wedge pressure during resuscitation - No refs in the rate of fluid administration section - Lactic acidosis - Points out that HCO can impair lactate utilization - Also states that arterial pH does not point out what is happening at the tissue level. Suggests mixed-venous sample.ReferencesJCI - Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia and a nice review of this topic: Altered Prostaglandin Signaling as a Cause of Thiazide-Induced HyponatremiaThe electrolyte concentration of human gastric secretion. https://physoc.onlinelibrary.wiley.com/doi/10.1113/expphysiol.1960.sp001428A classic by Danovitch and Bricker: Reversibility of the “Salt-Losing” Tendency of Chronic Renal Failure | NEJMOsmotic Diuresis Due to Retained Urea after Release of Obstructive Uropathy | NEJMIs This Patient Hypovolemic? | Cardiology | JAMAAnd by the same author, a textbook: Steven McGee. 5th edition. Evidence-Based Physical Diagnosis Elsevier Philadelphia 2022. ISBN-13: 978-0323754835The clinical course and pathophysiological investigation of adolescent gestational diabetes insipidus: a case report | BMC Endocrine DisordersSensitivity and specificity of clinical signs for assessment of dehydration in endurance athletes | British Journal of Sports MedicineDiagnostic performance of serum blood urea nitrogen to creatinine ratio for distinguishing prerenal from intrinsic acute kidney injury in the emergency department | BMC NephrologyThe meaning of the blood urea nitrogen/creatinine ratio in acute kidney injury - PMCLanguage guiding therapy: the case for dehydration vs volume depletion https://www.acpjournals.org/doi/10.7326/0003-4819-127-9-199711010-00020?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmedValidation of a noninvasive monitor to continuously trend individual responses to hypovolemiaReferences for Anna's voice of God on Third Spacing : Shires Paper from 1964 (The ‘third space' – fact or fiction? )References for melanie's VOG:1. Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American Heart Association2. excellent review of RAAS in pregnancy: The enigma of continual plasma volume expansion in pregnancy: critical role of the renin-angiotensin-aldosterone systemhttps://journals-physiology-org.ezp-prod1.hul.harvard.edu/doi/full/10.1152/ajprenal.00129.20163. 10.1172/JCI107462- classic study in JCI of AngII responsiveness during pregnancy4. William's Obstetrics 26th edition!5. Feto-maternal osmotic balance at term. A prospective observational study
In this riveting episode of Ted Speaks, we're joined by a veteran of the EHS field, Brian Zoeller of Johnson Controls. With over 25 years of experience under his belt, Brian shares his insights on the essential role technology plays in EHS processes. Get a sneak peek into how a renowned organization like Johnson Controls utilizes innovative tools like BESafe and leverages cutting-edge technologies— think cell phones, google glass, and drones—to ensure the safety of their workforce. Discover how this app, designed specifically for subcontractors, aids in identifying potential risks, ensuring compliance with OSHA standards, and how user feedback has transformed it over its five years of use. We also delve into some intriguing policies of JCI, such as the "no cell phone usage while driving" rule and the empowering "Stop Work" tool. But that's not all. Brian also emphasizes the importance of senior leadership's engagement in EHS matters and why safety should be a value deeply embedded in all decision-making processes. Intrigued? Tune in for the full discussion and learn from the best in the industry. We guarantee, it's an episode you won't want to miss!References: Safety FMTotal Health & Safety SolutionsBrian Zoeller, MS, CSPLinkedIn
Baer touches on the JCI hack, no whammies no whammies! And after giving you another banger of a product highlight we address some less-intrusive ways to really start helping the safety approach to the school shooter. Check it out. ChitChat: https://www.bleepingcomputer.com/news/security/building-automation-giant-johnson-controls-hit-by-ransomware-attack/ Product Highlight: www.controlbyweb.com - X410 Meat: https://www.securitymagazine.com/articles/99936-a-preventative-approach-to-school-safety-in-2023 S/O: @bestsecuritysystems on IG
This episode of the Fire Sprinkler Podcast is my conversation with Melisa Rodriguez. Melisa Discusses the high piled storage sprinkler system that has been available from Tyco/JCI for a a years, Melisa was brought on on to help push the storage market for JCI. We discuss the certifications required to install the Quell systems, the process to get certified, and why Quell systems are beneficial for high piled cold storage arrangementsEnjoy!
Lunch Hour подкастын ээлжит дугаарт үндэсний ууган компаниудын нэг Алтай Холдинг ХХК-ийн ерөнхийлөгч Б.Самади уригдаж өөрийн ажлын карьер, хувийн түүх, Солонгосын сүлжээ дэлгүүр "Emart"-ийн салбарыг Монголд нутагшуулсан туршлага, JCI Монгол байгууллагын үйл ажиллагаа зэрэг олон сонирхолтой сэдвүүдийн талаар ярилцлага өрнүүллээ.-Guest Facebook - https://www.facebook.com/smd32Guest Instagram - https://instagram.com/samadibHost Instagram - https://www.instagram.com/ankhbayarts/Host Twitter - https://twitter.com/ankhyabar-Та https://lemonpress.mn/ -д и-мэйл хаягаа бүртгүүлээд Монголын Хөрөнгийн Биржээс, Уолл Стрит, Цахиурын Хөндий хүртэлх дотоод, гадаадын бизнесийн зах зээлийн онцлох мэдээллүүдийг ажлын өдрүүдийн 07:00 цагаас чанасан кофе, шарсан өндөгтэйгөө хамт хүлээж аваарай. -Facebook - https://www.facebook.com/lemonpress.mnInstagram - https://www.instagram.com/lemonpress.mn/Twitter - https://twitter.com/LEMONPRESSincLinkedIn -
The JCI has been the best performing market in ASEAN, up close to 3% on a year to date basis. Jerry Goh, ASIA Equities, Investment Manager at ABRDN tells us if this positive momentum will continue for the year and what are the reasons for this bullishness.Image credit: Shutterstock.com
When it comes to preparing our workforce for today and future careers, the Community College of Allegheny County is a top resource for students and lifelong learners to acquire new skillsets in a flexible, cost-effective manner Dr. Quintin Bullock, CCAC President and Dr. Stephen Wells, CCAC Interim Chief Academic Officer joined the TEQ Magazine Education Focus Roundtable to focus on how CCAC is building for the future (this is not yesterday's community college). Learn how CCAC is building for the future with: Strong connections and partnerships with business and industry (Google, BNY Mellon, CNX, JCI, AHN, UPMC etc.) State of the art facilities housing groundbreaking technology in the classrooms and opportunities for innovative instruction (CEIT), fueling educators with what they need in tomorrow's teaching and learning environment (CTL) Expanded and new programs and curriculum as well as experienced, dynamic faculty to educate and train the workforce and meet the needs of a diverse population of students
In this episode, we speak with Harald Horgen, a renowned expert in helping technology companies expand into new business models and markets. With over 25 years of experience, Harald has worked with a wide range of companies, from early-stage and VC-funded firms to industry giants such as JCI, ABB, Ericsson, Schneider Electric, Olympus, BASF, Siemens, and many others.Harald's specialties include business strategy and go-to-market plans for IIoT and connected products, SaaS business model transformation, software business strategy, channel strategy, partner development, international expansion, and establishing strategic alliances.Harald shares his insights on what it takes to take repeatable IP solutions to market and the organizational structure needed to be successful. He also discusses his experience building indirect channels for enterprise solutions across Asia, the Americas, EMEA, and Africa, helping software companies transition their business model from on-premise, perpetual licenses to cloud-based subscriptions, and working with global manufacturers to design the right go-to-market strategy for their IoT solutions.The York Group, of which Harald is a part, is a preferred vendor with Microsoft, and he talks about how this partnership has helped him and his clients succeed. Whether you're a startup or an established company looking to expand your business, Harald's insights are sure to be valuable. Tune in to learn more about his expertise in technology expansion and growth.
This Episode of the Fire Sprinkler Podcast, I go head to head with Nick Martin from JCI in a race to see who can install faster. Me with a regular threaded ESFR, and him, doubling me up with the Rapid Install ESFR. We discuss the development, how contractors are accepting it, and more! Recorded in Austin Texas at the NFSA Conference and Expo!
In this episode, VP of Marketing Cesar Torres chats with VP of Membership Brandon Roque. They talk about Brandon's career as a field representative for Senator Scott Wilk and some of his exciting hobbies. Brandon will be facilitating an upcoming self defense training for JCI Santa Clarita. Check out JCI's website or social media for details. Secrets of Tomorrow's Leaders is available on YouTube, Facebook, Apple Podcasts, Google Podcasts, and Spotify.
In this podcast from AHR 2023, Brandon Marshall from Chemours and Chris Forth from JCI talk about the future of refrigerants and Opteon XL41 (R-454B). Refrigerant regulations are changing to pave the way for lower-GWP refrigerants, but M1 is also in full swing. M1 refers to the U.S. Department of Energy's implementation of the new efficiency standards for A/C units and heat pumps (SEER2, EER2, etc.). These standards changed the equipment testing procedure to match field conditions more closely. Opteon is the next-generation portfolio of low-GWP refrigerants for Chemours as a successor to the legacy refrigerants in the Freon product line. These refrigerants are a response to the HFC phasedown outlined in the AIM Act. JCI chose to use Opteon XL41, an HFO, for its equipment due to Opteon XL41's low GWP compared to R-32 and because of the similar operating pressures and temperatures to R-410A. A2Ls are a permanent change in the industry, and their safety considerations and best practices are here to stay. However, even though A2Ls are more flammable than A1 refrigerants, they are nowhere near as flammable as A3 refrigerants. Just about any refrigerant can propagate flame under the right conditions (including A1s), so A2Ls are only a little bit more flammable than those. Brandon, Chris, and Bryan also discuss: Brandon and Chris's industry experience The transition from CFCs to HCFCs to HFCs Refrigerant reclamation Upcoming GWP limits Hydrofluoroolefins (HFOs) A2L refrigerant product testing Staying up to date on A2L training resources Some of the prominent flammable refrigerant trainers Smuggled and counterfeit refrigerants Learn more about the 4th Annual HVACR Training Symposium or buy a virtual ticket today at https://hvacrschool.com/symposium. If you have an iPhone, subscribe to the podcast HERE, and if you have an Android phone, subscribe HERE. Check out our handy calculators HERE.
Welcome to another episode of Just Checking In. Today our guest is Joe Williams, a tech writer, formerly of Bloomberg, Business Insider, and, most recently, Protocol. But with Protocol's shutdown, Joe had time for us at JCI and offered us an interesting perspective on the state of the media today, including insights about how he likes to cover complicated, B2B technology stories. . This expert in covering wonky tech issues joins the conversation in this episode to talk about the landscape of media business models, the do's and don'ts of covering technology issues, and how to craft a great story. Plus, he's got an interesting viewpoint on Elon's Twitter. Join technology comms pros Becky Buckman and Keyana Corliss as they cut to the heart of today's tech-news cycle and the general craziness that is high-tech corporate communications right now. With a short, not-too-serious take on the industry - with plenty of humor and irony thrown in - they'll bring you the best in the biz, across comms and media together, for one-of-a-kind insights and perspectives you won't hear anywhere else!Jump straight into:03:31 - Catching up with Protocol shutdown - “The media is not immune to everything going on, and particularly when you're in a niche industry, or maybe not niche, but when you're a beat publication and the industry you're covering is going through a tough time, it's pretty evident that that's gonna filter down to you.” 07:39 - The landscape going forward for the media business - “I think fear that consumers aren't going to want to pay, I think it's misguided because I think they don't want to pay for journalism that they don't want or that they don't find useful.”09:20 - The model of self-started journalism - “I worry about kind of tunnel vision or I worry about not having that second set of eyes or that, that newsroom to kind of, you know, bounce ideas off of.”13:52 - What makes a good story within the tech comms industry - “ I think to still talk about it like it's some futuristic like Star Trek concept is really disadvantageous. And frankly, I think kind of insulting to the reader”26:23 - The biggest tech comms PR turnoffs - “Companies now I think, always fear that reporters are always digging for something, which is funny to me cuz that's our job and that's what we should be doing.” 28:47 - Joe's refreshing perspective regarding Twitter - “It's a self-fulfilling cycle. He says something, we write about it, and he says something else. We write about it. There has to be a breaking point that it's, you know, but I don't know what happens, besides him shutting down the website.” Episode resources:Joe Williams's Twitter and LinkedInThank you for listening to Just Checking In by Battery Ventures. Go follow Becky and Keyana on social media to know more about them. If you enjoyed this show leave a review and help us find new audiences! This show is produced by StudioPod Media in SanFrancisco. Teresa Buchanan is the Show's Producer. Nicole Genova is the Show...
In this episode recorded live at AHR Expo 2023, Matthew from JCI (Johnson Controls) joins Bryan to talk about rooftop unit (RTU) retrofit facts and considerations. When doing an RTU retrofit, you want to make sure you know the budget before anything else; larger budgets will allow you to implement things like VFDs and even VAV technology. In many cases, you may consider adding an economizer for "free" cooling and energy savings. You also want to know what you will get out of a retrofit in terms of value, especially when it comes to system efficiency and longevity. Some common IAQ upgrades for RTUs include improved filtration, especially with MERV 13 filters. Economizers also allow you to control the amount of outside air with the help of an exhaust system or even barometric relief. UV lighting can also be used in light commercial RTUs. When doing a retrofit, you'll want to pay attention to the existing equipment's footprint. Sticking to that footprint will make the replacement aspect easier. The utility and electrical infrastructure are also important to consider, as you won't want to replace the existing piping, wiring, and connections. With regulations and technology constantly changing, it helps to be able to contact the manufacturer to assist with the retrofit process. Companies like JCI are trying to assist contractors with installations by providing guidance and education in the field. Matthew and Bryan also discuss: Matthew's professional experience at JCI Adding economizers and VFDs Convertible filter racks Cost-benefit analysis resources Changing regulations Interfacing with the manufacturer during the retrofitting process To learn more about JCI, visit https://www.johnsoncontrols.com/. Learn more about the HVACR Training Symposium or buy a virtual ticket today at https://hvacrschool.com/symposium. If you have an iPhone, subscribe to the podcast HERE, and if you have an Android phone, subscribe HERE. Check out our handy calculators HERE.
Junior Chamber International (JCI) is a nonprofit that is world wide. JCI is a nonprofit that is dedicated to helping young people become leaders in their community by creating positive changes. In this episode President of JCI Lansing Kristin Rhine and past President of JCI Lansing Angela Fossi explain what it is JCI does and its goals for the community and its members. JCI Lansing will be hosting an event Saturday, December 3rd 2022 called " Stuff The Bus" at the Walmart in Eastwood Town Centre Lansing Mi. "Stuff The Bus" Facebook Information Want to be a part of a group people that are searching to be better everyday then be sure to join the Rising Above Community Facebook Group The Video portion of this podcast can be watched on YouTube The audio portion of this episode can now be found on all your personal favorite podcast streaming service. Apple Podcast Spotify All Rising Above Content JCI Lansing: JCI Lansing Facebook Website: JCI Lansing Website Kristin Rhine Email: kerhine@gmail.com
Otis Worldwide (OTIS) manufactures elevators and escalators and its customers include residential, commercial, and infrastructure projects. George Tsilis discusses OTIS as an overlooked stock as its earnings were released October 26th. He talks about how OTIS's shares traded higher after earnings. He notes that the company's net sales are down 7.6% and organic are sales up 0.8%. He then compares OTIS to XLI, JCI, SPX, and XHB. Tune in to find out more about the stock market today.
In this episode, Koren chats with Aimee Fishwick, Nicole Fauth, and Katie Collins, the 2022 co-chairs of Santa's Helpers SCV. They talk about their their long history as best friends, some of their favorite memories, and why they wanted to chair one of JCI's flagship events this year. This incredible program provides gifts to hundreds of local children in underserved communities. Volunteers from all over the Santa Clarita Valley are encouraged to be a part of the process of making the holidays brighter for everyone. For more details, check out https://santashelpersscv.com or visit us on social media.Secrets of Tomorrow's Leaders is available on YouTube, Facebook, Apple Podcasts, Google Podcasts, and Spotify.
In part one of our podcast with Chris Forth, VP of regulatory, codes and environmental affairs for JCI, we tackle the new HVAC tax credits included in the Inflation Reduction Act.
In part one of our podcast with Chris Forth, VP of regulatory, codes and environmental affairs for JCI, we tackle the new HVAC tax credits included in the Inflation Reduction Act.
Building HVAC Science - Building Performance, Science, Health & Comfort
“A day in the life of a smart building. Now spaces have memory and identity.” Now more than ever, facility owners and managers are incorporating smarter and more connected building technologies to improve proactive maintenance, reduce energy use, and create operational efficiencies. On todays' podcast, Vineet Sinha, VP of Product management at Johnson Controls joins us to shed light on how connected building systems are operating holistically and working together to create a truly smart environment. Buildings of the future are here today and can do all this. It sounds complex, but these smart buildings cost a lot less to run and use fewer resources, all while ensuring indoor spaces are clean and safe. In this discussion, we walk listeners through a day in the life a smart building from the perspective of an everyday occupant and explain how connected technologies enable an experience that makes people feel comfortable, safe and in control. Vineet shares with us definitions of a building persona and how building are moving to cognition of the occupants. You can connect with Vineet on LinkedIn at: https://www.linkedin.com/in/sinhavineet/ Learn more about JCI's Open Blue Solutions at: https://www.johnsoncontrols.com/openblue This episode was recorded in Oct 2022.
Isaac got his LEA in summer of 2012, he's done a little bit of everything in this industry ever since. He enjoys service work, feeling it's more interesting and engaging than install. Currently Isaac holds a NICET II, and certs for C-Cure 9000 and Ocularis VMS. Having worked for Siemens, JCI, Point Monitor, and currently with Stanley/Securitas, Isaac is a well rounded tech that we're very excited to chat with If you would like to be a part of our show, then make sure you send us an email talking about your experiences in the trades, and we'll read it on the show. Tips and tricks? Let us know and we can share them with our listeners. Send an email to halfwattpod@gmail.com We're interested in hearing more stories and having more guests from the Union on our show. While I'm an instructor for one agency, we at Half Watt Pod are bigger than that and would love to learn more about all technicians. Be sure to reach out if you want to help educate people on a career path that can change their life. You can follow us on Instagram @halfwattpod where you can enter for contests and keep up with new from our show.
References for chapter 8Robert Schrier proposed a unifying hypothesis to explain the sodium retention seen in edematous states like cirrhosis and heart failure, coining the term effective arterial blood volume (EABV). An open access review in JASN 2007 can be found here: https://jasn.asnjournals.org/content/18/7/2028#ref-3 John P PetersASN Annual Award: https://www.asn-online.org/about/awards/award.aspx?awh_key=0ea83199-f86d-4506-9507-d7e4ce688cb4Short article discussing contributions of Dr. Peters by mentees Dr. Franklin Epstein and Dr. Donald Seldin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588700/ and https://pubmed.ncbi.nlm.nih.gov/12097739/Epstein FH et al. Studies of the antidiuresis of quiet standing: the importance of changes in plasma volume and glomerular filtration. JCI 1950. In this classic report, investigators studied their own sodium excretion supine, standing and with a variety of maneuvers (saline or albumin infusion) and showed that urinary sodium excretion is limited in the upright position compared to supine position. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436228/pdf/jcinvest00414-0077.pdfAn interesting review of early concepts on hypertension feature notes on John J Hay and Paul Dudley White. The former was known to say, “The greatest danger to a man with high blood pressure lies in its discovery because then some fool is certain to try and reduce it!” and the latter has been quoted as saying that hypertension might be compensatory but apparently, these quotes are out of context. To find out what they really said, check out: Elias MF and Goodell AL. Setting the record straight for two heroes in hypertension John J Hay and Paul Dudley White. J Clin Hypertens 2019 https://onlinelibrary.wiley.com/doi/epdf/10.1111/jch.13650 VA Cooperative Trial was an important study to establish the hypertension should, in fact, be treated The VA Cooperative Study and the Beginning of Routine Hypertension Screening, 1964-1980 This study was stopped after only 18 months because of an excess of deaths in the untreated group who had a mean diastolic BP of 115 mmHg. For a long time, only the diastolic BP was felt to be important until the Systolic Hypertension in Elderly Patients (“SHEP study”) clarified that treatment of isolated systolic hypertension is also importantPrevention of Stroke by Antihypertensive Drug Treatment in Older Persons With Isolated Systolic HypertensionWe continued to try to grapple with the work of Jens Titze on sodium which turns many of our assumptions about sodium upside down. His team studied astronauts on a long term high sodium diet and found an unexpected weekly (circaseptan) rhythm seemingly related inversely to aldosterone and directly with cortisol. His work also probes our notion of body sodium content. For a great first hand read, check out Dr TItze's review in Kidney International 2014 which he aptly dubs, “Spooky Sodium Balence.” https://www.sciencedirect.com/science/article/pii/S0085253815562807Epstein M. The cardiovascular and renal effects of head-out of water Immersion in Man. Circulation Research 1976 Cardiovascular and renal effects of head-out water immersion in man: application of the model in the assessment of volume homeosSpace flight is an exaggeration of the water immersion experiments. Astronauts on either a low or normal sodium diet had a reset of natriuetic peptides. A Salty Tale: Study Examines Sodium Regulation in Space and Natriuretic Peptide Resetting in Astronauts | CirculationBaroreceptors feature mechanically activated ion channels called PIEZO1 and PIEZO2. Zeng W, Marshall KL, Min S, Daou I, Chapleau MW, Abboud FM. PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex. Science 2018 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102061/We also relearned an unfortunate truth: lots of folks pee in pools. De Laat et al. Water Res. 2011. Concentration levels of urea in swimming pool water and reactivity of chlorine with urea At the American College of Cardiology meeting in April, investigators shared the news that the combination of an ARB with new class of drugs called angiotensin receptor neprilysin inhibitor (ARNI) was not superior to ACE inhibitors at reduction of heart failure following acute MI. Here's the press release for the PARADISE-MI trial. Prospective ARNI vs. ACE inhibitor trial to DetermIne Superiority in reducing heart failure Events after Myocardial InfarctionA series of elegant experiments by Alicia McDonald's team to characterize pressure natriuresis. In these studies, they induce hypertension by constriction of the superior mesenteric artery, the celiac artery and the infrarenal aorta (essentially increasing afterload without directly altering the blood flow to the kidney). With this maneuver, the blood pressure of the experimental animal rises, urinary sodium excretion increases and then they demonstrate a shift in the Na-H ATPase from the apical membrane to intracellular vesicles in the proximal tubule and a shift in NCC from the luminal membrane to the intracellular vesicles in the distal tubules. Yang L et. al Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity. Am J Physiol Renal 2002 https://journals.physiology.org/doi/full/10.1152/ajprenal.00298.2001?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.orgLee DH Riquier ADM, Yang LE, Leong PK, Maunsbach and McDonough AA. Acute hypertension provokes acute trafficking of distal tubule NaCl (NCC) to subapical cytoplasmic vesicles. Am J Physiol Renal Physiol. 2009 Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles This review in KI reports is also worth a read McDonough AA. Maintaining Balance under pressure-hypertension and the proximal tubule. 2015 ISN Forefronts Symposium 2015: Maintaining Balance Under Pressure—Hypertension and the Proximal Tubule
Johnson Controls is on a mission to make buildings smarter and to transform the environments in which we live, work, learn and play.In this episode, we're talking with Marc Vandiepenbeeck, Vice President and Chief Financial Officer of North American Building Solutions at Johnson Controls. It's a fascinating discussion about the digitization of building controls, smart buildings, smart supply chains, and how digitization is impacting every aspect of the business, including finance.Get ready to take notes. Because we're not just talking about emerging technologies - but how to know when and where to invest in digital solutions, how to focus on value-add for the customer, how to carry these strategies along your entire supply chain, and the value of risk taking in innovation.3 Big Takeaways from this episode:The ultimate goal of digitization is to make a better product for the end user: Like every sector, building controls are being transformed by digitization. But without a clear focus, organizations will be lost in the noise of all the digital technologies and solutions they could invest in. Marc reminds us that digitization (in building solutions) enables JCI to bring multiple systems and products together in one connected smart building, making it easier for the building owner to control their smart solutions.The two biggest drivers of technology in finance: Big Data and RPAs: Big Data enables JCI to bring all their disparate data into one dataset, analyze it and make better business decisions, especially around supply chain and market intelligence. RPAs (robotic process automation) automate many of the low-skill activities in the finance team, enabling humans to do value-added tasks that give them a more fulfilling work experience.A crucial key to success in 2022 is getting smart about your supply chain: We discuss how to use technologies like Big Data to understand your entire supply chain, forecast future demand, and feed those insights all the way back up the value chain. This is especially crucial in sectors like building controls and construction where an organization is managing multiple supply chains at once. Find out why we might be moving away from just-in-time manufacturing and toward a system of smart connected supply chains.ResourcesTo learn more about Johnson Controls, visit: https://www.johnsoncontrols.com/Connect with Johnson Controls on social media:YouTube | LinkedIn | Facebook | Instagram | TwitterEpisode page: https://techedpodcast.com/johnsoncontrols/
Mizuho has a neutral rating on Stanley Black & Decker (SWK). Brett Linzey discusses the outlook for industrial stocks. He talks about other industrial stocks doing well. Mizuho has a buy rating on AME, ALLE, DOV, ETN, FLS, HON, HUBB, JCI, and ZWS. He also goes over movement in crude oil futures (/CL). Tune in to find out more.
Ben Schneider is a German self-made serial entrepreneur. He is E-Commerce Consultant and the founder of Jobmofy.com, which is a premium job search platform for hiring remote workers overseas. He runs a digital marketing agency and owns the world's biggest e-commerce store for sea monkeys. Ben reached the 10 million in sales milestone within 14 months by only using Facebook & Instagram ads. He wrote an Amazon bestseller in Germany titled “Facebook Marketing for Entrepreneurs” which was a 4-month bestseller in the 3 related categories on Amazon. In 2020, he founded the printed magazine "Jobmofy Magazine" with around 40,000 readers all around the world. He is also the host of the Business & Lifestyle LEGENDS Podcast with guests like Neil Patel, David Meltzer, Omar Zenhom, and John Lee Dumas. He is a JCI member and was honored by the ERFOLG Magazine in Germany (engl. success magazine) as the TOP expert in Online Marketing in Germany, Austria, and Switzerland. One year later, they named Ben one of the top 500 influencing people in the world of success in Germany, Austria, and Switzerland. Where to Find Ben Schneider Website: https://benschneider.biz/ (https://benschneider.biz/) Instagram: https://www.instagram.com/benschneider87/ (@benschneider87) LinkedIn: https://www.linkedin.com/in/ben-schneider-a74820109/ (Ben Schneider) Youtube: https://www.youtube.com/channel/UCflGY1n1rAmw56J_9Bi2-0w (Ben Schneider) Facebook: https://www.facebook.com/benjamin.schneider.735 (Ben Schneider) SPONSOR This episode is sponsored by http://www.entireproductions.com/ (Entire Productions)- Creating events (both in-person and virtual) that don't suck! and http://www.entireproductionsmarketing.com/ (Entire Productions Marketing)- carefully curated premium gifting and branded promo items. PLEASE RATE, REVIEW, & SUBSCRIBE on APPLE PODCASTS “I love Natasha and the Fascinating Entrepreneurs Podcast!”
Serendipitous events – a chance encounter, the right word at the right time – may seem to be a matter of random luck or the whim of the universe. But what if serendipity is not actually a matter of pure chance? Might we have more control over luck than we think? Guest Dr. Christian Busch explores what's really behind serendipitous moments in this fascinating conversation. He explains how we can make accidents meaningful…and how we can create more meaningful accidents. Dr Christian Busch is the bestselling author of Connect the Dots: The Art & Science of Creating Good Luck and is a Visiting Fellow at LSE, from which he holds a PhD and Msc. Christian is the Director of the CGA Global Economy Program at New York University, where he teaches on purpose-driven leadership, entrepreneurship, emerging markets, and (social) innovation. He is also the co-founder of Sandbox Network, a global community of young innovators, as well as of Leaders on Purpose, an organization convening leading CEOs. Christian is among Diplomatic Courier's 'Top 99 Influencers', JCI's 'Ten Outstanding Persons', and on the Thinkers50 Radar list of 30 management thinkers “most likely to shape the future of how organizations are led." He is a member of the World Economic Forum's Expert Forum and a Fellow of the Royal Society of Arts and frequently speaks at conferences such as the World Economic Forum, TED/TEDx, and Financial Times Sustainability Summit. Christian previously worked in business and consulting in Mexico, Germany, the UK, and the US. He has served as Senior Advisor at multinational companies and the National Entrepreneurs Association, on Ashoka's Selection Panel, on the Global Shapers Steering Committee, and on the Jury of the African Entrepreneurship Award. And be sure to subscribe to The Self-Employed Life in Apple Podcasts or follow us on Spotify or wherever you listen to podcasts so you don't miss an episode. Everything you need can all be found at jeffreyshaw.com. Christian Busch, thank you so much for being here! Remember, you might be in business FOR yourself but you are not in business BY yourself. Be your best self. Be proud and keep changing the world. Guest Contact – Connect the Dots: The Art & Science of Creating Good Luck TheSerendipityMindset.com Christian Busch on Twitter (@ChrisSerendip) Christian Busch on LinkedIn (/in/christianwbusch) Serendipity Mindset on Facebook (@SerendipityMindset) Contact Jeffrey – JeffreyShaw.com Books by Jeffrey Shaw Business Coaching for Entrepreneurs The Self-Employed Summit Watch my TEDx LincolnSquare video and please share! Valuable complimentary resources to help you – The Self-Employed Business Institute You know you're really good at what you do. You're talented, you have a skill set. The problem is you're probably in a field where there is no business education. This is common amongst self-employed people! And, there's no business education out there for us! You also know that being self-employed is unique and you need better strategies, coaching, support, and accountability. The Self-Employed Business Institute, a five-month online education is exactly what you need. Check it out! Take The Self-Employed Assessment! Ever feel like you're all over the place? Or frustrated it seems like you have everything you need for your business success but it's somehow not coming together? Take this short quiz to discover the biggest hidden gap that's keeping you from having a thriving Self-Employed Ecosystem. You'll find out what part of your business needs attention and you'll also get a few laser-focused insights to help you start closing that gap. Have Your Website Brand Message Reviewed! Is your website speaking the right LINGO of your ideal customers? Having reviewed hundreds of websites, I can tell you 98% of websites are not. Fill out the simple LINGO Review application and I'll take a look at your website. I'll email you a few suggestions to improve your brand message to attract more of your ideal customers. Fill out the application today and let's get your business speaking the right LINGO! Host Jeffrey Shaw is a Small Business Consultant, Brand Management Consultant, Business Coach for Entrepreneurs, Keynote Speaker, TEDx Speaker and author of LINGO and The Self Employed Life (May 2021). Supporting self-employed business owners with business and personal development strategies they need to create sustainable success.
Chapter 7ReferencesSands JM, Blount MA and Klein JD. Regulation of Renal Urea Transport by Vasopressin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116377/In this invited piece, Sands and colleagues explain that although urea is permeable across membranes, this is slow, thus urea transporters in the kidney, under control of vasopressin, are needed to facilitate transport and create the medullary gradient. Text book using 20% of extracellular compartment being in the intravascular compartment. https://courses.lumenlearning.com/ap2/chapter/body-fluids-and-fluid-compartments-no-content/ another one: https://med.libretexts.org/Bookshelves/Anatomy_and_Physiology/Book%3A_Anatomy_and_Physiology_(Boundless)/25%3A_Body_Fluids_and_Acid-Base_Balance/25.2%3A_Body_Fluids/25.2B%3A_Fluid_Compartments The chapter I wrote where I went through the math in figure 7-3. It was a major revelation to me: https://docs.google.com/document/d/17BM1xihvlztuQlU8GVNhEDoPLzr6GounHYZAtVUkLvw/edit?usp=sharing Association Between ICU-Acquired Hypernatremia and In-Hospital Mortality https://journals.lww.com/ccejournal/fulltext/2020/12000/association_between_icu_acquired_hypernatremia_and.26.aspx Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients https://pubmed.ncbi.nlm.nih.gov/30948456/ Edelman IS, Leibman J, O'Meara MP and Birkenfeld LW. Interrelations between serum sodium concentration, serum osmolarity and total exchangeable sodium, total exchangeable potassium and total body water. JCI 1958. This classic paper calculates the total body exchangeable sodium and potassium and establishes the relationship between these. Understanding this painstacking work helps understand the effect of supplementing potassium in the setting of hyponatremia. https://dm5migu4zj3pb.cloudfront.net/manuscripts/103000/103712/cache/103712.1-20201218131357-covered-e0fd13ba177f913fd3156f593ead4cfd.pdfEdelman is the Root of Almost All Good in Nephrology https://www.renalfellow.org/2014/11/20/edelman-is-root-of-almost-all-good-in/ Jens Titze and his team published a pair of articles that shocked those interested in salt and water in JCI in 2017. High Salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation https://www.jci.org/articles/view/88532Increased salt consumption induces body water conservation and decreases fluid intake https://www.jci.org/articles/view/88530in this exciting exploration of the basic assumptions that we hold true regarding salt and water (and staring Russian cosmonauts and an incredible controlled simulation of salt and water intake), Titze shows that high sodium intake does not simply drive water consumption (as we usually teach) but instead leads to a complex hormonal and metabolic response (even with diurnal variation!) and results in body water conservation and decreased water consumption. And accompanying editorial from Mark Zeidel: salt and water, not so simple. https://www.jci.org/articles/view/94004In addition, Titze and others have done interesting work on sodium deposition in tissues where it may also be a source for systemic inflammation.https://pubmed.ncbi.nlm.nih.gov/28154199/Jens Titze talking about salt, water, thirsting a TEDx talk. https://www.youtube.com/watch?v=jQQPBmnIuCY A discussion/debate of the overfill vs. underfill theory of edema in the nephrotic syndrome (hint- overfill theory triumphs) would be incomplete without a reference to congenital analbuminemia. This reference from Frontiers in Genetics explores the diagnosis, phenotype and molecular genetics and reveal that patients tend to have only mild edema but severe hyperlipidemia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478806/The finding that proteinuria can directly lead to sodium retention based on a study when puromycin aminoglycoside induced proteinuria of one kidney lead to sodium retention by that kidney which was localized to the distal nephron. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436841/?page=9Plasmin may be the culprit at the level of the epithelial sodium channel based on Tom Kleyman's work: https://jasn.asnjournals.org/content/20/2/233Amiloride may help! (stay tuned for amiloride in a future episode) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016639/An old favorite of JC's from the Kidney International feature which debates the cause of edema in the nephrotic syndrome.https://www.sciencedirect.com/science/article/pii/S0085253815583075Under protest, we hobbled through a discussion of the Gibbs Donnan affect even encouraged by one of Amy's fellows based on this article from QJM: https://academic.oup.com/qjmed/article/101/10/827/1520972 suggesting that our understanding of the role of hyponatremia in fractures might be all wrong- it could be related to hypoalbuminemia.
0:01 - Introduction2:33 - Adam's Introduction4:40 - Why Kitchen Suppression Hasn't Taken Off10:08 - Mechanical vs. Electronic Suppression13:25 - Firing of Suppression Systems15:18 - Ghost Kitchens18:40 - How Panels are Connected21:57 - NFPA 17 & 17a23:32 - Chemical Suppression in Dry Applications27:45 - How Kitchen Workers are Being Affected 30:18 - Lowering Costs on Inspections34:10 - Final Thoughts on Kitchen Suppression35:50 - Aaron Rodgers' Luscious Locks37:00 - Conclusion
Animals don't hold grudges right? RIGHT‽ You be the judge after hearing the tale of one sleepy Northern Japanese town which was besieged by the biggest, baddest bear in Hokkaido. More Michael Myers or Jason Vorhees than Winnie the Pooh, this bear meant business and wasn't going to stop until the town fell silent.Join Linz and Chris as they journey north into the blizzards to uncover the truth about the Tomamae brown bear incident.------Music / Sound Effect credits--------Music by JCI-21 from PixabayMusic by lololeeds from PixabayMusic by SSPsurvival from PixabayMusic by beetpro from PixabayMusic from PixabaySound from Zapsplat.comSound from Quicksands.comSounds from freesound.orgThanks to our Patreons Philipp Hofmann, Pip, Livvy, Mark, Philipp Hofmann, Riaz K, Wesley Aker & Michael P McCoy.Support the show