Podcasts about Inflection

Today, I'm joined by Danielle DuBoise, co-founder of Sakara Life. With 15 years in business, Sakara has evolved from plant-based meal delivery service to full-blown functional food and supplement brand with a focus on gut and metabolic health. In this episode, we discuss turning operational complexity into a competitive advantage. We also cover: Fresh food logistics Raising capital selectively Navigating trends vs. nutrition science Subscribe to the podcast → insider.fitt.co/podcast Subscribe to our newsletter → insider.fitt.co/subscribe Follow us on LinkedIn → linkedin.com/company/fittinsider  Sakara's Website: www.sakara.comSakara on Instagram: https://www.instagram.com/sakaralife/ Danielle on Instagram: https://www.instagram.com/DanielleDuboise/  - The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com to learn more about its smart fitness ecosystem for fitness and health facilities. Fitt Talent: https://talent.fitt.co/Consulting: https://consulting.fitt.co/Investments: https://capital.fitt.co/ Chapters: (00:00) Introduction (01:15) Company evolution (02:45) Meal delivery complexity (05:45) Operational moat (07:45) Nutrition messaging (09:25) Education and product delivery (10:25) Resisting trends (12:45) Brand philosophy (15:15) "Eat clean, play dirty" (16:45) Maintaining premium brand (18:30) Inflection points (19:15) Nationwide shipping unlock (21:15) Fiber era opportunity (23:00) Growth strategy shift (24:30) Analog and micro-influencers (25:40) Leadership transition (28:15) Raising capital selectively (29:40) Where to find (30:41) Conclusion

Why do some podcasters instantly connect with their audience while others struggle to keep listeners engaged? The answer lies in one word: Prosody. In Part 3 of our series with David Goldberg, founder of Edge Studio, we dive deep into the "how" of human communication. David explains that it's not just what you say, but how you say it—your pitch, tempo, tone, and rhythm—that makes all the difference. We explore why this essential skill is rarely taught in schools and how you can harness your natural pitch to mask nervousness and project confidence. Whether you're a seasoned host or just starting out, David's insights on effective vocal patterns will dramatically elevate your podcast presence.     ⏱️ Accurate YouTube Chapters & Timestamps 0:00 Welcome & Introduction to David Goldberg   0:57 Prosody: The one word that defines how you say your words   1:36 What is Prosody? Inflection, intonation, pitch, and rhythm   2:12 The Education Gap: Why prosody isn't taught in grade school   3:24 The Fear of Public Speaking: How a lack of training leads to humiliation   5:54 Communication Skills: The key to success in corporations and colleges   6:52 The Search for Synonyms: Why "speaking patterns" doesn't cover it all   7:51 Prosody for Podcasters: Breaking down the seven categories   9:52 Pitch: The musical note of your voice and its role in engagement   11:28 Masking Nerves: How lowering your pitch increases credibility   13:00 Finding Your Natural Pitch: The humming and meditation techniques   15:00 Pitch Range Exercises: Moving from monotone to engaging   18:00 Tempo: The speed of your words and the importance of clarity   21:00 Handling Single-Syllable Words: Ensuring your audience can decipher the message   23:00 Tone and Volume: Tailoring your voice to the topic and audience   25:30 Pacing and Spacing: The rhythm of your delivery   26:50 Variety: Keeping the listener engaged through vocal shifts   74:11 Final Advice: Loosening up and having fun with your performance   74:52 Where to Find David: Edge Studio and coaching services   76:31 Outro: RoyCoughlan.com and the PodFather Network   76:53 End of Episode    

  Why do some podcasters instantly connect with their audience while others struggle to keep listeners engaged? The answer lies in one word: Prosody. In Part 3 of our series with David Goldberg, founder of Edge Studio, we dive deep into the "how" of human communication. David explains that it's not just what you say, but how you say it—your pitch, tempo, tone, and rhythm—that makes all the difference. We explore why this essential skill is rarely taught in schools and how you can harness your natural pitch to mask nervousness and project confidence. Whether you're a seasoned host or just starting out, David's insights on effective vocal patterns will dramatically elevate your podcast presence.     ⏱️ Accurate YouTube Chapters & Timestamps 0:00 Welcome & Introduction to David Goldberg   0:57 Prosody: The one word that defines how you say your words   1:36 What is Prosody? Inflection, intonation, pitch, and rhythm   2:12 The Education Gap: Why prosody isn't taught in grade school   3:24 The Fear of Public Speaking: How a lack of training leads to humiliation   5:54 Communication Skills: The key to success in corporations and colleges   6:52 The Search for Synonyms: Why "speaking patterns" doesn't cover it all   7:51 Prosody for Podcasters: Breaking down the seven categories   9:52 Pitch: The musical note of your voice and its role in engagement   11:28 Masking Nerves: How lowering your pitch increases credibility   13:00 Finding Your Natural Pitch: The humming and meditation techniques   15:00 Pitch Range Exercises: Moving from monotone to engaging   18:00 Tempo: The speed of your words and the importance of clarity   21:00 Handling Single-Syllable Words: Ensuring your audience can decipher the message   23:00 Tone and Volume: Tailoring your voice to the topic and audience   25:30 Pacing and Spacing: The rhythm of your delivery   26:50 Variety: Keeping the listener engaged through vocal shifts   74:11 Final Advice: Loosening up and having fun with your performance   74:52 Where to Find David: Edge Studio and coaching services   76:31 Outro: RoyCoughlan.com and the PodFather Network   76:53 End of Episode    

Winshear Metals CEO Richard Williams joined Steve Darling from Proactive to provide an update on the company's exploration activities in Scotland and northwestern Ontario, highlighting a series of upcoming catalysts expected to drive news flow throughout the year. At the company's nickel-copper-cobalt project in Scotland, Winshear recently completed a drilling program aimed at expanding known mineralization in both the North and South zones. Williams said drilling indicates the North Zone may be widening toward the west and remains open for further expansion, while the South Zone successfully intersected the targeted sulphide mineralization at depth. Although assay results are still pending, Williams noted that previous drilling by the project's option vendor returned high-grade nickel, copper, and cobalt mineralization, supporting the project's potential as a significant critical minerals asset. In parallel, the company is advancing metallurgical testing and additional geophysical surveys to further evaluate and refine exploration targets. “The North Zone looks like visually it's getting wider to the west, so it's completely open,” Williams said. In Ontario, Winshear is advancing its large-scale gold project near Thunder Bay, where it has assembled a 360-square-kilometre land package along the eastern extension of the prospective Shebandowan Greenstone Belt. Exploration completed last year identified several large gold anomalies, including the six-kilometre-long Inflection target and the four-kilometre-long El Dorado target. To further define these targets, the company has launched a detailed soil sampling program and drone-based magnetic survey. The goal is to generate multiple drill-ready targets by the end of the summer and position the project for future drilling. With pending drill assays, metallurgical results, geophysical surveys, and ongoing exploration work across both projects, Winshear believes it is entering a catalyst-rich period that could significantly advance its portfolio of critical minerals and precious metals assets. #proactiveinvestors #winshearmetals#tsxv #wins #mining #portsoynickel #NickelExploration #GoldExploration #CriticalMinerals #ScotlandMining #OntarioMining #CopperExploration #Cobalt #MiningNews #ResourceDiscovery

In this episode of The Circuit, Ben and Jay dive deep into Apple's WWDC announcements, unpacking the "applied AI" strategy behind the newly indexed Siri, system-level CPU scheduling updates, and Apple's surprising embrace of Nvidia for private cloud compute. Ben also shares his takeaways from the Nebius conference in San Francisco, analyzing their unique custom server racks and their positioning as a highly capable neo-cloud infrastructure provider. Finally, Jay reports back from his recent trip to China, sharing ground-level observations on why US entity list restrictions are losing their impact, how IoT chipmaker Espressif creatively markets globally via Reddit and YouTube despite domestic blocks, and the real-world manufacturing bottlenecks facing humanoid robot actuators.

What if the biggest threat to your business is already unfolding - and you can't see it yet? And what do you need to be thinking about ahead of tax time? In this episode, we hear two expert perspectives on getting ahead of small problems before they become serious ones. First, executive coach Chris Power explains why “leadership inflection points” can become dangerous moments for organisations, and how strong leaders recognise early warning signs before performance stalls. Then, dual-qualified solicitor and chartered accountant Adam Ahmed of Entity Accountants shares practical advice on staying tax-compliant in a fast-changing landscape, including the risks around crypto, digital payments, and poor planning. If you’re considering launching a podcast to grow your authority and client base, reach out to our team to learn how we can support you. Business Essentials is produced by soundcartel.com.auSee omnystudio.com/listener for privacy information.

AI Valley examines the "innovator's dilemma," where tech giants like Google hesitate to release advanced AI that might cannibalize their lucrative search advertising profits. This "bigness" often slows innovation, leading geniuses like Mustafa Suleyman to leave DeepMind at Google to found independent ventures like Inflection. However, the staggering cost of GPUs and computing power often pulls these startups back into the orbit of trillion-dollar corporations. For example, Suleyman eventually moved Inflection to Microsoft to leverage their near-bottomless cash reserves. This dynamic ensures that only the wealthiest companies with massive reach can truly compete in the expensive race for generative AI supremacy. (5/8)1905 LA

The housing crisis is real. So why isn't modular construction fixing it?Dwayne Torrey is the Director of Construction and Infrastructure at CSA Group — the organization that writes the standards every builder, regulator, and manufacturer in Canada has to follow. He's been working at the intersection of modular construction and policy for seven years, and his answer might surprise you: the technology isn't the problem. The rulebook is.In this episode we get into how consensus standards actually get written, who's fighting in the room when they do, and why a 1972 document about school portables is still shaping how Canada builds homes today.

NEW BOOK -- The Price of Becoming Buy it -- www.LearningLeader.com/Becoming The Learning Leader Show with Ryan Hawk This is brought to you by Insight Global. If you need to hire one person, hire a team of people, or transform your business through Talent or Technical Services, Insight Global's team of 30,000 people around the world has the hustle and grit to deliver. Jim Collins is the author of some of the most influential business books ever written — Good to Great, Built to Last, and Great by Choice. His concepts have become part of the leadership vocabulary. Level 5 Leadership. The Flywheel. First Who, Then What. The Hedgehog Concept. He spent more than a decade at Stanford as a professor and has advised CEOs, four-star generals, and heads of state. His new book is What to Make of a Life: Cliffs, Fog, Fire, and the Self-Knowledge Imperative. It is the product of ten years of research and is the most personal thing he has ever written. We flew to Boulder, Colorado, to record this one in person with Jim. Key Learnings Jim's grandfather wrote his own death story. Jimmy Collins was a test pilot in the 1930s. He told Jim's grandmother, Dolores, that if he died, she should pull the last chapter from his desk and publish it. He died in a test crash. After the service, she pulled out the chapter. The title was "I'm Dead." The last chapter, written in first person, described the plane coming out of the sky, the screaming wings, the crash. The final words, by his own pen: "I am dead now." For seven decades, his grandmother never cried. When Jim asked her in her nineties to tell the story of his grandfather, she cried and said, "Thank you for that. I've never cried before." She'd been a single mom in the middle of the Depression. Of all the things Jim feels good about in his life, asking her to tell that story before she died at almost 100 years old is one he's most proud of. A cliff is an event that alters the trajectory of your life and forces you to reconstruct everything that comes after. Jim's first big cliff: he lost his father while his father was still alive. Jim's father took the family to San Francisco in the 1960s. They lived a few houses down from Haight Street. When a man was shot dead on their doorstep, Jim's mom moved them to Boulder. They lived in a cold basement with cots and a hot plate. They couldn't afford a Christmas tree, so Jim and his brother rolled a boulder into the basement and called it their Christmas rock. The Greyhound bus moment. In high school, Jim took a Thanksgiving turkey on a Greyhound bus down to New Mexico, where his father was living in an adobe hut with a dirt floor. He had this romantic vision: they'd cook the turkey, share Thanksgiving, bond as father and son. The whole weekend, his father had no interest in him. He spent it trying to convince Jim to convince his grandmother to give him money. On the bus ride home, looking out the window into the fog, Jim realized: there will never, ever be a father there. No male role models. No frameworks. No guidance. "I've got this one life. What do I do with it?" The inflection point in Jim's life is Joanne. They got engaged four days after their first date. He'd admired her from afar for years but never had the courage to ask her out. Once they were together, Jim began a conscious process: I need to become a person worthy of being married to her. He didn't know exactly what that meant or how to get there. But he knew that was the work. Forty-six years later, it's still a never-ending journey. What Joanne does brilliantly: she sees what needs attention. Jim is encoded to hear it. Someone once asked Joanne what she thought Jim's greatest strength was. She said: "Jim takes critical feedback better than any person I've ever met." Joanne sees what needs attention. Jim hears it. Then they adapt and adjust. That's the inner flywheel of their marriage. Circle the wagons together. Guns pointing out, never at each other. When life gets really difficult, whether it's disease or other cliffs. You are always together. Always on the inside of the wagons. Never aimed at each other. Joanne won the 1985 Hawaii Ironman by 92 seconds. With a hamstring injury that limited her running training to 16 miles a week, she came off the bike with a 10-minute lead. Then mile by mile, the lead shrank. Nine minutes. Eight. Seven. With a few miles left, she stopped in the middle of the lava field, massaging her legs, almost pleading with them to run. She looked up at the sky. Then her gaze fixed somewhere down the road. She started to run. You're racing for self-respect. Joanne told Jim afterward: in the end, you're racing to know that you couldn't have run a step faster. Only you'll know. If you know you couldn't have run a step faster, that's actually winning. When Jim writes, he's on the lava fields. When he finishes a book, he wants to know he couldn't have written one sentence better. When you're on the lava fields, this is the moment you want to quit. Don't. Writing is thinking. When the writing isn't working, the thinking isn't clear. Go back to the data. Find the through-line. There are three types of luck: What luck. A cancer diagnosis. A guitar left in an empty house. An event that breaks your way. Who luck. The people who walk into your life. Joanne. Morten Hansen. Jerry Porras. Bill Lazier. Zeit luck. When what you're doing intersects with the surrounding zeitgeist. Jimmy Page was in Surrey when the British rock explosion happened. Luck is an event you didn't cause, with significant consequences, and an element of surprise. The big winners weren't luckier. They had a higher return on luck. What you do with luck events matters more than the luck itself. Bill Lazier: the closest thing to a father Jim ever had. Jim ended up in Bill's class at Stanford because the class he was trying to take was full. The random course-sorting mechanism threw him into the first class Bill ever taught. Pure WHO luck. Jim did not cause that.  Discover your encodings. An encoding is a durable capacity of your intrinsic construction that resides within, awaiting discovery through the experiences of life.  Jim has done over 300 online courses on every imaginable subject. Constitutional law. Napoleon. World War I. The history of China. He started them to learn how to teach. Then his curiosity took over. That's what an encoding looks like in the wild. You have a constellation of encodings. Like stars. When your life captures a bright set of those encodings, you're in frame. When it doesn't, you're out of frame. The same person can look amazing in frame and not very amazing out of frame. The most important finding from this book: don't follow anyone else's advice. Their advice is well-meaning. It may have worked beautifully for them. But it worked for them because it flowed from their encodings. And their encodings are not your encodings. Barbara McClintock and Grace Hopper. Two women who won the Nobel Prize and shaped computer science. McClintock was encoded for solitary work. She didn't even have a phone. She heard about her Nobel Prize on the radio. Hopper was encoded to work through people. She kept a pirate flag in her office and once stole furniture for her team in the middle of the night. Two completely different encodings. What they shared: their lives were in alignment with their encodings. Leadership is the art of getting people to want to do what must be done. It's not a trait. It's a choice. Anyone in any organization can lead, depending on their desire to make a difference. Nobody needs to wait for a title. Ryan's encoding is "the relentless persistence of invitation." Jim observed that Ryan has incredible encodings for what he'd describe as attractive persistence. Not pushy. Not aggressive. But persistent and welcoming. The invitation never goes away. The way you lead should be different from everyone else. Because you are encoded differently. Trust your encodings, not their playbook. Roger Sherman saved the U.S. Constitution. Twice. He created the bicameral legislature compromise. He insisted the Bill of Rights be amendments, not rewrites. Yet most people don't know his name. He almost never spoke. He listened in committees and waited for the precise moment to introduce just the right point to turn American history. Quiet. Behind the scenes. Uncharismatic. Unglamorous. Enormously effective. That was his encoding. You should largely ignore what other successful leaders did. It's marvelous to listen to. It might give you ideas. But everything that worked for them reflected their encodings, not yours. The work isn't to copy their playbook. The work is to discover your encodings and trust them. The color of Jim's fire changed. When he was younger, his fuel was rage, fury, and a sense of terror with no safety net. He used to worry that if he ever lost it, he'd lose his drive. What replaced it was a different kind of fire: the joy of curiosity, of being lost in giant projects, of marvelous conversations, of sharing what he's learned. His drive is higher than ever. It just feels a lot better now. The 3x3 reflective practice. After almost any conversation, teaching moment, or significant interaction, Jim writes down three things that went well and three things he could have done better. He's done it for years. He's now systematizing it. He doesn't pause to celebrate. He pauses to learn quickly and move on. At the top of Jim's notes for this conversation: "The biggest reminder for today, reconnecting with an old friend." That's the celebration. What could be a better celebration than reconnecting with somebody you've had marvelous conversations with? Reflection Questions What is your most significant cliff? What did you reconstruct on the other side, and what are you still rebuilding? What are your encodings? Not what you've been told you should be, but what genuinely flows from your intrinsic construction. When have you felt most in frame? Like Jim with Joanne, is there a person or purpose you are actively trying to become worthy of? What would that work look like this week? More Learning #397: Jim Collins - Creating Your Generosity Flywheel, Make the Trust Wager (Part 1)#398: Jim Collins - Creating Your Generosity Flywheel, Make the Trust Wager (Part 2) #216: Jim Collins - How to Go From Good to Great  

Welcome to episode 478 of the Mobile Tech Podcast with guest Enobong Etteh of Booredatwork -- brought to you by Mint Mobile. In this week's show, we focus on inflection points: how Samsung's Galaxy Buds4 Pro, Apple's MacBook Neo, and Mercedes-AMG's E53 wagon are changing the game in their respective categories. We then share our first impressions of the Honor 600 and discuss how we use AI as creators. Finally, we cover news, leaks, and rumors from Hyundai, NTT Research, Adobe, and OpenAI. Episode Links- Support the podcast on Patreon: https://www.patreon.com/tnkgrl- Donate / buy me a coffee (PayPal): https://tnkgrl.com/tnkgrl/- Support the podcast with Mint Mobile: https://mintmobile.com/mobiletech- Enobong Etteh: https://www.threads.net/@booredatwork- Enobong's Samsung Galaxy Buds4 Pro comparison: https://www.youtube.com/watch?v=OFUCCDHzTYQ- Enobong's Apple MacBook Neo comparison: https://www.youtube.com/watch?v=L6qn0q7jpRo- Enobong's ASUS ZenBook A16 review: https://www.youtube.com/watch?v=DnsUPE4Qx08- Honor 600 review: https://www.androidpolice.com/honor-600-review/- Mercedes-AMG E53 wagon review: https://www.tomsguide.com/vehicle-tech/evs/i-drove-the-mercedes-amg-e53-hybrid-wagon-for-a-week-and-i-felt-like-i-was-in-an-iron-man-suit- Hyundai bringing fake gear shifts to more EVs: https://www.autoblog.com/news/hyundai-is-bringing-fake-gear-shifts-to-more-evs- NTT Research Upgrade 2026 recap: https://www.enterprisetimes.co.uk/2026/04/15/turning-research-into-reality-at-upgrade-2026/- Adobe Summit 2006 recap: https://www.jonpeddie.com/news/enterprise-solutions-in-the-spotlight-at-adobe-summit-2026/- OpenAI is making a phone: https://www.gsmarena.com/openai_phone_to_use_a_custom_dimensity_9600_soc_launch_fasttracked_kuo-news-72679.phpAffiliate Links (If you use these links to buy something, we might earn a commission)- Samsung Galaxy Buds 4 Pro: https://amzn.to/428bRBI- OnePlus Buds Pro 3: https://amzn.to/4dfF5DA- Apple MacBook Neo: https://amzn.to/3ORAMGM- ASUS Zenbook A14: https://amzn.to/49HF1eX- Honor 400: https://amzn.to/4ntrqxK

Invest Like the Best: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- My guest today is Alex Karnal. Alex is the co-founder and managing partner of Braidwell, a life sciences investment firm he built after spending 15 years at Deerfield Management. The frame we use throughout the episode is the health stack. Alex talks about how most of the diseases that will claim most of our lives are already addressable with medicines that exist today. We work through the five layers of what a defensive health strategy looks like, why GLP-1 medicines represent the first commercial proof that people are ready to be proactive about their health, and why PCSK9 inhibitors may ultimately be the more important drug class even though they get far less attention. We also get into the science and business of drug discovery itself — why most of the published literature that AI companies are training on cannot be replicated, what it would mean to have a truly agentic scientific lab running 24 hours a day, and why Alex believes we are now on a deterministic curve toward scientific superintelligence in biology. For the full show notes, transcript, and links to mentioned content, check out the episode page ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠.  ----- Become a Colossus member to get our quarterly print magazine and private audio experience, including exclusive profiles and early access to select episodes. Subscribe at ⁠colossus.com/subscribe⁠. ----- ⁠Ramp's⁠ mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Go to⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠ramp.com/invest⁠⁠ to sign up for free and get a $250 welcome bonus. ----- Trusted by thousands of businesses, ⁠Vanta⁠ continuously monitors your security posture and streamlines audits so you can win enterprise deals and build customer trust without the traditional overhead. Visit ⁠vanta.com/invest⁠.  ----- ⁠WorkOS⁠ is a developer platform that enables SaaS companies to quickly add enterprise features to their applications. Visit⁠⁠ ⁠WorkOS.com⁠⁠⁠ to transform your application into an enterprise-ready solution in minutes, not months. ----- ⁠Rogo⁠ is the AI platform for finance. They're building agents for Wall Street that are trained to understand how bankers and investors actually do work: from diligence and modeling, to turning analysis into deliverables. To learn more, visit rogo.ai/invest. ----- ⁠Ridgeline⁠ has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. Visit⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ridgelineapps.com⁠. ----- Editing and post-production work for this episode was provided by The Podcast Consultant (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://thepodcastconsultant.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠). Timestamps: (00:00:00) Welcome to Invest Like the Best (00:02:29) Intro: Alex Karnal (00:03:15) State of the Union: GLP1s and Life Sciences (00:07:01) The Health Stack Framework (00:12:49) Breaking Down the 5 Defensive Layers (00:21:18) GLP-1: What's Driving the Inflection (00:28:28) Diet vs. Drugs: Is Food Enough? (00:31:15) Barriers to Access: Complexity, Cost & Compliance (00:35:04) PCSK9: The Closest Thing to a Free Lunch (00:44:10) Alzheimer's & Neurodegenerative Disease (00:46:59) Cancer: Early Detection & New Treatments (00:54:49) Body Imaging & Diagnostic Trade-offs (00:56:31) How Drugs Are Discovered (01:02:39) AI in Drug Discovery (01:10:57) The Automated Lab of the Future (01:13:05) Peptides & Citizen Pharmacology (01:16:45) Alex's Background (01:28:25) Braidwell's Investment Approach (01:30:39) The Kindest Thing

My guest today is Alex Karnal. Alex is the co-founder and managing partner of Braidwell, a life sciences investment firm he built after spending 15 years at Deerfield Management. The frame we use throughout the episode is the health stack. Alex talks about how most of the diseases that will claim most of our lives are already addressable with medicines that exist today. We work through the five layers of what a defensive health strategy looks like, why GLP-1 medicines represent the first commercial proof that people are ready to be proactive about their health, and why PCSK9 inhibitors may ultimately be the more important drug class even though they get far less attention. We also get into the science and business of drug discovery itself — why most of the published literature that AI companies are training on cannot be replicated, what it would mean to have a truly agentic scientific lab running 24 hours a day, and why Alex believes we are now on a deterministic curve toward scientific superintelligence in biology. For the full show notes, transcript, and links to mentioned content, check out the episode page ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠.  ----- Become a Colossus member to get our quarterly print magazine and private audio experience, including exclusive profiles and early access to select episodes. Subscribe at ⁠colossus.com/subscribe⁠. ----- ⁠Ramp's⁠ mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Go to⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠ramp.com/invest⁠⁠ to sign up for free and get a $250 welcome bonus. ----- Trusted by thousands of businesses, ⁠Vanta⁠ continuously monitors your security posture and streamlines audits so you can win enterprise deals and build customer trust without the traditional overhead. Visit ⁠vanta.com/invest⁠.  ----- ⁠WorkOS⁠ is a developer platform that enables SaaS companies to quickly add enterprise features to their applications. Visit⁠⁠ ⁠WorkOS.com⁠⁠⁠ to transform your application into an enterprise-ready solution in minutes, not months. ----- ⁠Rogo⁠ is the AI platform for finance. They're building agents for Wall Street that are trained to understand how bankers and investors actually do work: from diligence and modeling, to turning analysis into deliverables. To learn more, visit rogo.ai/invest. ----- ⁠Ridgeline⁠ has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. Visit⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ridgelineapps.com⁠. ----- Editing and post-production work for this episode was provided by The Podcast Consultant (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://thepodcastconsultant.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠). Timestamps: (00:00:00) Welcome to Invest Like the Best (00:02:29) Intro: Alex Karnal (00:03:15) State of the Union: GLP1s and Life Sciences (00:07:01) The Health Stack Framework (00:12:49) Breaking Down the 5 Defensive Layers (00:21:18) GLP-1: What's Driving the Inflection (00:28:28) Diet vs. Drugs: Is Food Enough? (00:31:15) Barriers to Access: Complexity, Cost & Compliance (00:35:04) PCSK9: The Closest Thing to a Free Lunch (00:44:10) Alzheimer's & Neurodegenerative Disease (00:46:59) Cancer: Early Detection & New Treatments (00:54:49) Body Imaging & Diagnostic Trade-offs (00:56:31) How Drugs Are Discovered (01:02:39) AI in Drug Discovery (01:10:57) The Automated Lab of the Future (01:13:05) Peptides & Citizen Pharmacology (01:16:45) Alex's Background (01:28:25) Braidwell's Investment Approach (01:30:39) The Kindest Thing

Was haben Himbeeren mit Werwölfen zu tun? Und was diese wiederum mit einem Bräutigam oder dem Vergessen? Ganz klar: Alle diese Worte haben Bestandteile, die nur ein einziges Mal in der deutschen Sprache vorkommen: Him-, Wer-, -gam und gess-. Jakob erklärt uns in dieser Folge, was es mit diesen sogenannten unikalen Morphemen auf sich hat: Woher kommen sie, warum gibt es sie und was bedeuten sie?Ein Podcast von Anton und Jakob. Instagram: https://www.instagram.com/sprachpfade ___ Links & Literatur: Artikel „Bräutigam“, „Brombeere“, „Himbeere“, „Nachtigall“, „vergessen“, „Werwolf“, in: Wolfgang Pfeifer et al., Etymologisches Wörterbuch des Deutschen (1993), digitalisierte und von Wolfgang Pfeifer überarbeitete Version im Digitalen Wörterbuch der deutschen Sprache, https://www.dwds.de/d/wb-etymwb.Artikel „буженина“ (transliteriert: buženina), in: Николай Шанский, Валерий Максимович, Васильевич Иванов, Тамара Васильевна Шанская (1971): Краткий этимологический словарь русского языка. пособие для учителей. Изд. 2-е, испр. и доп. Москва: Просвещение. стр. 61.Artikel „cranberry“, in: Etymonline. Online Etymology Dictionary, https://www.etymonline.com/word/cranberry.Artikel „galan“, in: Albert L. Lloyd, Rosemarie Lühr (Hg.) (2009): Etymologisches Wörterbuch des Althochdeutschen, Bd. IV, Sp. 22, https://ewa.saw-leipzig.de/articles/49880.Artikel „körsbär“, in: Elof Hellquist (1948): Svensk Etymologisk Ordbok, Bd. 1, 3. Aufl., Lund, S. 552.Artikel „ver-“ in: Digitales Wörterbuch der Deutschen Sprache, https://www.dwds.de/wb/ver-.Geert Booij u.a. (Hg.) (2000): Morphologie. Ein internationales Handbuch zur Flexion und Wortbildung, 1. Halbband = Morphology. An International Handbook on Inflection and Word-Formation, Volume 1, Berlin/New York (darin: Artikel Nr. 14, 46, 86 und 87).Wolfgang Fleischer/Irmhild Barz (2012): Wortbildung der deutschen Gegenwartssprache, 4. völlig neu bearbeitete Auflage, Berlin/Boston.Alle Literatur ausleihbar in deiner nächsten Bibliothek! ___ Gegenüber Themenvorschlägen für die kommenden Ausflüge in die Sprachwissenschaft und Anregungen jeder Art sind wir stets offen. Wir freuen uns auf euer Feedback! Schreibt uns dazu einfach an oder in die DMs: anton.sprachpfade@protonmail.com oder jakob.sprachpfade@protonmail.com ___ Titelgrafik und Musik von Elias Kündiger https://on.soundcloud.com/ySNQ6

In this episode of Run the Numbers, CJ sits down with Praveer Melwani, CFO of Figma, to unpack the financial model behind one of tech's most iconic product-led companies. They cover viral growth, forecasting without a traditional sales pipeline, AI credit pricing, margin tradeoffs, and the metric Praveer believes matters most in the long run: free cash flow per share.—SPONSORS:EY works with high-growth tech companies to navigate the messy realities of scaling—from regulatory requirements to IPO readiness. By helping teams get it right early and often, EY lets founders stay focused on building while reducing risk as they grow. Learn more at https://www.ey.com/techstartupsSpendHound is a SaaS spend management platform built for finance and procurement teams that want visibility and leverage in every deal. By tracking all your software, benchmarking pricing across thousands of vendors, and surfacing contracts and renewals, SpendHound helps you stop overpaying and negotiate with confidence. Trusted by teams at ZoomInfo and Hootsuite. Get started at https://www.spendhound.comBrex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metricsAleph is a modern FP&A platform built for teams that want more than another planning tool. By connecting your ERP, CRM, and other systems into one trusted data layer with AI workflows, Aleph helps you move faster with real-time insights. Get a personalized demo at https://www.getaleph.com/runRightRev is an automated revenue recognition platform built for teams that have outgrown spreadsheets and billing tool workarounds. It handles high-volume subscriptions, usage-based contracts, and mid-cycle upgrades, so you can scale without scrambling at month-end. For RevRec that keeps your books clean, visit https://www.rightrev.com/CJRillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cj—LINKS: Mostly Talent: https://mostlymetrics.typeform.com/to/cLTxtAsNGuest: https://www.linkedin.com/in/praveer-melwani/Company: https://www.figma.com/CJ: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—TIMESTAMPS:0:00 Preview and intro1:21 Welcome and guest intro2:55 From banking to Dropbox to Figma5:04 Inflection points: building trust early8:36 TAM expansion thinking10:31 Sponsors — EY | SpendHound | Brex13:38 Two-thirds of Figma users aren't designers14:36 Forecasting product led growth16:22 Cohorts and NDR discovery17:39 LTV to CAC philosophy18:57 Product signals for account expansion20:22 How Figma achieved hypergrowth with 90%+ margins22:14 AI expands TAM: time to hit the gas23:22 AI credit pricing model24:50 Sponsors — Aleph | RightRev | Rillet28:13 Outcome based pricing consideration29:00 Where AI margins settle: gross profit dollars30:08 Free cash flow per share as north star31:04 NDR and pricing volatility32:13 Bundled vs. unbundled seats34:50 Being engaged in sales to understand admin pain35:17 IPO day experience36:27 Keeping employees focused beyond the stock price37:19 Employee stock pressure and lockup reality39:37 Kitchen cabinet of advisors41:44 How to ask better questions of advisors41:47 Lightning round41:50 Advice to younger self42:47 Finance software stack44:09 Claude WTF moment: forecasting model throughput45:13 Craziest expense story: the haircut45:59 Credits

As we continue working on some new episodes for you, enjoy this look back at our episode from September with John O'Donnell, the visionary founder behind the clothing brand, Johnnie-O. Summary: When John O'Donnell founded Johnnie-O in 2005, his goal was to create a brand that combined East Coast prep with West Coast surf culture. 20 years later, you'll find their surfer logo in golf pro-shops and menswear stores across the country.Today, John joins us to share his incredible journey from being a walk-on on the UCLA golf team to founding one of America's most iconic golf brands.We get into the origins of Johnnie-O, discuss the source of their customer loyalty, and talk about their impressive growth over the last two decades.Highlights:The opportunity John saw in 2005 (2:05)John's midwest roots (4:46)UCLA Golf team (5:50)Johnnie-O's differentiation (6:45)The origins of Johnnie-O (8:17)Distribution (9:28)Inflection point for the brand (10:28)Marketing evolution (11:37)Scale of growth (13:57)Breaking into women's wear (16:30)Avenues for growth (17:35)Tariffs (18:30)Outlook for Johnnie-O (20:27)Competitive Landscape (22:15)Lessons learned (23:13) Links:Johnnie-O LinkedInJohnnie-O WebsiteICR LinkedInICR TwitterICR Website Feedback:If you have questions about the show, or have a topic in mind you'd like discussed in future episodes, email our producer, joe@lowerstreet.co.

A conversation between Matt Landau and Alex Zemianek on navigating the uncertainty of AI while staying grounded in what matters most: family, purpose, and authentic leadership in business. From raising kids in a rapidly changing world to building a values-driven vacation rental company, Alex shares a refreshing perspective on using technology not out of fear—but as a tool to enhance human connection, hospitality, and meaningful impact. Reach out to Matt directly: matt@vrmb.com

The 2026 NFL Draft is just two weeks away, and it is time to take a look at key NFL Draft inflection points for the Pittsburgh Steelers. What is the plan heading into the 3-day selection process? Join Andrew Wilbar, Jeremy Betz, and Corey Eckenroth on the latest Steelers Fix podcast! This podcast comes courtesy of the Steel Curtain Network and FFSN, the Fans First Sports Network. Check out Meinelschmidt Distillery at meineldistillery.com and use the code SCN6 to save 10% at checkout! Learn more about your ad choices. Visit megaphone.fm/adchoices

Simon Erickson is back with three major investing trends that every growth investor needs on their radar in 2026. First up: weight loss drugs are bigger than ever, with oral GLP-1 pills from Novo Nordisk and Eli Lilly now winning broad insurance coverage and slashing out-of-pocket costs — potentially tripling the total addressable market to $190 billion by 2035. Then Simon breaks down the picks-and-shovels plays powering the AI data center buildout — including co-packaged optics, on-demand fuel cell energy, and quantum computing — and makes the case for why Bloom Energy may be his top pick in the space right now.Finally, the episode covers what could be the largest IPO in history: SpaceX is reportedly targeting a $2 trillion valuation and a $75 billion raise as soon as this summer — and the implications for the entire space economy are massive. From orbital data centers to Starlink's satellite internet dominance and the Starship launch vehicle, Simon breaks down what investors need to know before SpaceX goes public. Don't miss it — subscribe and visit 7investing.com for full recommendations and watch list access.Past episodes mentioned:GLP-1 Feud: https://youtu.be/CazBaRRT3HQData Centers in Space: https://youtube.com/live/Qmk84KLaX0Y?feature=shareStocks & Companies MentionedPublicly Traded:Novo Nordisk (NYSE:NVO)Eli Lilly (NYSE:LLY)Viking Therapeutics (NASDAQ:VKTX)Hims & Hers Health (NYSE:HIMS)Broadcom (NASDAQ:AVGO)Lumentum (NASDAQ:LITE)Bloom Energy (NYSE:BE)IonQ (NYSE:IONQ)Rocket Lab (NASDAQ:RKLB)MDA Space (TSX:MDA)Micron Technology (NASDAQ:MU)Zeta Global (NYSE:ZETA)NuScale Power (NYSE:SMR)NVIDIA (NASDAQ:NVDA)Alphabet / Google (NASDAQ:GOOGL)Microsoft (NASDAQ:MSFT)Meta Platforms (NASDAQ:META)Watch List Mentions (7Investing):Vail Resorts (NYSE:MTN)Sphere Entertainment (NYSE:SPHR)Ferrari (NYSE:RACE)IonQ (NYSE:IONQ) (also listed above)Private / Pre-IPO:SpaceX (private — IPO expected as soon as summer 2026)xAI (acquired by SpaceX, February 2026)Inflection (newly public quantum computing company — ticker not confirmed in transcript)Anthropic (private)Character.ai (private)Insurance / Healthcare Referenced:BlueCross BlueShield (not publicly traded)UnitedHealthcare / UnitedHealth Group (NYSE:UNH)Aetna / CVS Health (NYSE:CVS)#GLP1Stocks #WeightLossDrugs #OzempicStocks #SpaceXIPO #AIDataCenters #BloomEnergy #QuantumComputing #GrowthInvesting #StockMarket #EnergyStocks #SpaceStocks #Lumentum #Broadcom #NovoNordisk #EliLilly #InvestingIn2026 #TechStocks #PicksAndShovels #7investing #SimonErickson⚠️ This is not investing advice. Please do your own research before making any investment decisions.

In 2024, when he was the director of the Central Intelligence Agency, William Burns wrote in an essay in Foreign Affairs about “the plastic moments that come along only a few times each century”— and argued that “the United States faces one of those rare moments today, as consequential as the dawn of the Cold War or the post-9/11 period.” If that claim seemed bold at the time, events in the past couple of years have made it undeniable—a major war in Europe, two wars in the Middle East, sharpening U.S.-Chinese tensions, a U.S. administration committed to projecting power in new and disruptive ways, and technologies adding complexity across all of these other challenges. “Inflection point” is an overused term. But this is a moment when, as Burns argued in that essay, it really does fit. Before becoming CIA director, Burns was one of the most highly respected diplomats in recent American history. He started the secret negotiations that led to the Iran nuclear deal. He served as ambassador to Russia. As the State Department's top Middle East official, he warned internally of the consequences of invading Iraq in 2003. He has spent years sitting across the table from American allies and adversaries, trying to understand what drives them and how Washington should—and should not—deal with them. I spoke to Burns on the afternoon of April 1 about the course and consequences of the war in Iran, about Vladimir Putin and the war in Ukraine, about Xi Jinping and U.S.-Chinese competition, about the future of intelligence, and about what the Trump administration will mean for the future of American power.  You can find sources, transcripts, and more episodes of The Foreign Affairs Interview at https://www.foreignaffairs.com/podcasts/foreign-affairs-interview. 

What happens when successful leaders reach a moment where something simply feels “off”? In this episode of Daily Influence, Gregg-Brooke Koleno sits down with Dr. Bobby Hulme-Lippert, leadership coach, keynote speaker, award-winning storyteller, and author of Small Stories About Big Things. After two decades in professional ministry and serving in the U.S. Army chaplaincy, Bobby now helps mid- and late-career leaders navigate pivotal inflection points in their lives and leadership. Through storytelling, curiosity, and courageous conversations, Bobby guides leaders who feel stuck on the “hamster wheel” of busyness or disconnected from the energy and purpose they once had. In this conversation, Bobby shares how slowing down, asking better questions, and reconnecting with personal stories can help leaders realign themselves before influencing others. In this episode: • Why many leaders feel exhausted or misaligned despite outward success • How curiosity and powerful questions create stronger leadership cultures • The story of the “orange posts” and how small steps help leaders rediscover purpose • Why storytelling builds trust and strengthens responsible influence • How uncertainty and challenges can become invitations to growth Bobby reminds us that leadership transformation rarely happens through grand gestures. Instead, it often begins with small stories, thoughtful reflection, and the courage to pause long enough to realign with what truly matters. Learn more: https://bhl.coach

This episode explores Harris “Kuppy” Kupperman's framework for “inflection investing” and how he identifies asymmetric opportunities across global markets. The conversation dives into why he believes U.S. equities are structurally challenged, where he sees better opportunities globally, and how macro, politics, and capital flows drive major investing inflections.Inflection investing and identifying asymmetric opportunitiesHow macro and politics create winners and losers in marketsThe Argentina case study and why the stock exchange may outperform the countryHow to structure trades with limited downside and multi-bagger upsideTime horizon advantages versus short-term Wall Street thinkingPortfolio construction, capital allocation, and when to sell positionsManaging risk, leverage, and liquidity during crises and warsBuilding a “shopping list” during market dislocationsCountry ETFs vs individual securities in global investingWhy Kuppy prefers international markets over the U.S.The structural imbalances in the U.S. economy and stock marketWhy AI may lead to profitless growth and economic disruptionThe impact of AI on jobs, margins, and economic demandHow inflation distorts economic data and investor perceptionFinding opportunities in “left for dead” markets like BrazilThe role of elections and policy shifts in market inflectionsHow to think probabilistically about investmentsAvoiding unforced errors and emotional decision-makingThe importance of long-term thinking in volatile marketsPsychology and discipline in global macro investingHarris Kupperman Twitterhttps://twitter.com/HedgeyeKuppyPraetorian Capital Websitehttps://praetorian-capital.comTimestamps00:00 Why the U.S. stock market is structurally overvalued01:14 What “inflection investing” means02:54 Top-down vs bottom-up investing framework04:31 Using politics to identify winning trades05:00 Argentina trade setup and execution06:20 Why the Argentine stock exchange is the best play08:00 Earnings inflection and multiple expansion potential10:37 Time horizon and holding period strategy13:00 When to exit positions and recycle capital18:41 How and when to raise cash19:41 De-grossing the portfolio during crises23:14 Real-time decision making during war scenarios27:00 Building a shopping list during dislocations29:32 ETF vs individual stock decision process33:22 Why the U.S. is less attractive than global markets38:17 The problem with AI-driven “growth”43:31 Monitoring vs acting across global opportunities48:14 The psychology of long-term investing and edge

Navigating Career Transitions and Inflection PointsCareers rarely unfold in straight lines.In this episode, I'm sharing a conversation I originally recorded with strategist and executive coach Kathy Oneto about navigating career transitions and professional inflection points. We explore why careers often evolve through pivots rather than predictable steps up a ladder, and how moments of friction or curiosity can signal that it's time to rethink what comes next.We also discuss how creative professionals can stay resilient during periods of change by developing broader skillsets, building what I call “career insurance,” and surrounding themselves with communities that expand what feels possible.If you're questioning your next move, navigating a shift in your career, or thinking about how to stay relevant in a rapidly changing professional landscape, this conversation offers a thoughtful framework for approaching those transitions.In This Episode We DiscussWhy career transitions are often triggered by friction, curiosity, or unexpected circumstancesThe difference between careers that follow a linear “ladder” and those that evolve more like websHow to recognize when a professional pursuit is feeding your energy versus draining itWhy letting go of something you've built can be one of the hardest but most important career decisionsThe concept of building “career insurance” through adaptable skills and broader capabilitiesWhy developing a V-shaped skillset can create more resilience than narrow specializationHow major technological shifts like AI mirror previous industry disruptionsThe critical role community and professional networks play during periods of career transitionWhy navigating career change alone often makes the process harder than it needs to beAbout Kathy OnetoKathy Oneto is a strategist, executive and life-work coach, and speaker who helps individuals and organizations rethink how they pursue success and growth. She holds an MBA from the Haas School of Business at UC Berkeley and is the author of Sustainable Ambition: How to Prioritize What Matters to Thrive in Life and Work.Connect with KathyLinkedIn: https://www.linkedin.com/in/kathy-oneto/Book: Sustainable Ambition: How to Prioritize What Matters to Thrive in Life and Work_______________________________WEBSITEhttps://www.philipvandusen.comBRAND•MUSE NEWSLETTER  https://www.philipvandusen.com/museCREATIVE PROFESSIONAL COACHINGhttps://philipvandusen.com/oneononeYOUTUBEhttps://www.youtube.com/philipvandusenBRAND DESIGN MASTERS PODCAST https://podcast.branddesignmasters.com/subscribeBRAND STRATEGY 101 COURSEhttps://philipvandusen.com/bs101LINKEDINhttps://www.linkedin.com/in/philipvandusen/THREADShttps://www.threads.net/@philipvandusen FACEBOOKhttps://www.facebook.com/philipvandusen.agency/____________________________________Philip VanDusen is a branding consultant based in New York. A highly accomplished creative executive and expert in brand strategy, graphic design, marketing and creative management, Philip provides design, branding, marketing, career and business advice to creative professionals, entrepreneurs and companies on building successful brands for themselves and the clients and customers they serve.

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In this episode, Robert explores the concept of the “wisdom of crowds” and how market price action can reveal more than the constant stream of alarming headlines investors see every day. He explains why the market's resilience in the face of geopolitical tension, inflation fears, and technology-sector volatility may be sending an important signal about underlying demand for stocks. Robert discusses the balance between following the crowd and recognizing potential inflection points, what indicators he is watching that could change the trend, and why patience is often the best strategy during choppy, headline-driven markets. The episode also covers current technical signals, how he is managing risk and cash levels, and why surviving difficult trading environments is often the key to capturing the next major opportunity.

Justin, Rob, and J. Kyle Mann are back together, and they are here to take a look at some of the massive stories going on in the association this week. They start with Bam Adebayo's 83-point game against the Wizards and the discourse around his achievement. Then they talk about Shai Gilgeous-Alexander potentially locking up the MVP after his game-winning shot against the Nuggets. They also get into Victor Wembanyama leading the Spurs to wins in 16 of their past 17 games and talk about just how good they are. Last, they wrap up by discussing the Hornets and whether they are this season's Pacers. (0:00) Intro (2:53) Bam Adebayo (25:25) Fan Duel ad break (26:53) Tommy Hilfiger ad break (28:47) SGA (46:24) Wemby and the Spurs (1:04:12) Hornets Hosts: Justin Verrier, Rob Mahoney, and J. Kyle Mann Producers: Victoria Valencia and Isaiah Blakely Production Supervision: Ben Cruz and Conor Nevins Additional Production Support: John Richter and Chris Wohlers Explore more at⁠ https://tommy.com⁠ The Ringer is committed to responsible gaming. Please visit www.rg-help.com to learn more about the resources and helplines available. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this episode, Russ Branzell, President and CEO of CHIME, speaks with PV SubbaRao, President of Healthcare Provider at NTT DATA, about what it truly takes to operationalize AI for lasting transformation. Together, they discuss the leadership decisions, governance structures, and workflow redesign required to scale AI responsibly while driving measurable improvements in financial sustainability, operational resilience, and care delivery.Key Takeaways:Why AI represents a structural shift in healthcare operations and the signals that indicate organizations have reached a true transformation inflection point.The governance, data architecture, and investment decisions required to successfully move AI initiatives from pilot programs to enterprise-scale deployment.How leading organizations are redesigning clinical and operational workflows, roles, and decision-making structures as AI becomes embedded into everyday work.What distinguishes true AI-enabled revenue cycle transformation from traditional automation efforts and how it can support long-term financial sustainability.The leadership, cultural shifts, and performance metrics required to align the C-suite and measure the real impact of AI-driven transformation across the enterprise.

Early in his career, Intekhab Nazeer found himself sitting in go-to-market meetings rather than finance reviews. A CFO mentor had pushed him beyond traditional accounting responsibilities, exposing him to pipeline discussions and sales forecasting. That experience changed how he viewed finance leadership. Instead of simply reporting financial results, he began understanding “how pipeline is generated, how deal flow is measured, how the forecasting really works,” Nazeer tells us. The exposure reshaped his perspective, shifting his mindset from reporting outcomes to influencing them.The shift became even more real when he stepped into an interim CFO role after his mentor moved on. Responsibility changed overnight. “I was no longer supporting decisions. I was making decisions,” Nazeer tells us, describing board meetings, capital allocation choices, and the balancing act between growth and risk.Throughout his career, he continued to place finance alongside operations rather than apart from them. At one venture-backed company, that mindset proved critical. Revenue targets were being met, yet something felt wrong. When Nazeer overlaid unit economics—customer acquisition cost, payback period, and expansion revenue—he discovered the company was optimizing growth while quietly locking in unprofitable customer behavior, he tells us.The response required collaboration rather than spreadsheets alone. He worked with sales and product leaders to redefine the ideal customer profile, adjust pricing discipline, and elevate metrics like payback period and the “magic number” into core operating indicators, he tells us.The experience reinforced a lesson he carries today: the CFO role is “far less about spreadsheets and more about psychology,” Nazeer tells us. Precision creates accuracy, but influence creates outcomes.

From Steel Mills to Quantum Scale-Up: Inside Illinois's Bold Bet on the Future of ComputingWhat does it take to build the world's largest dedicated quantum technology park — on the site of a former steel mill? Harley Johnson is leading that effort, and the answer involves equal parts materials science, economic development, and a 30-year bet on quantum that's finally paying off.Why This Episode MattersIf you're following the quantum computing industry's path from lab prototypes to commercial-scale systems, this episode maps the terrain. Harley Johnson — a computational materials scientist turned CEO of the Illinois Quantum and Microelectronics Park (IQMP) — explains how Illinois assembled a unique combination of federal research funding, state economic investment, national labs, and top-tier universities into a 128-acre technology park designed to solve the quantum industry's hardest problem: scaling up.Whether you're a researcher, a founder, a policymaker, or someone trying to understand where quantum jobs and applications are actually headed, this conversation lays out how one state is building the infrastructure — physical, institutional, and human — to make large-scale quantum computing real.What You'll LearnHow a 1994 bet on quantum mechanics in a mechanical engineering lab led to directing the largest dedicated quantum tech park in the worldWhy Illinois chose a "beyond silicon" strategy for the CHIPS and Science Act — and how landing 4 of the first 10 federal quantum centers positioned the state for what came nextHow IQMP's public-private governance model works: a university-governed LLC partnering with private developers, accountable to the public while incentivizing industryWhy the park deliberately hosts a diverse portfolio of hardware modalities — including PsiQuantum, IBM, Inflection, Dirac, and Pascal — and how that mirrors venture portfolio thinkingHow IQMP's algorithm center connects quantum hardware companies with Fortune 500 end users in finance, insurance, energy, logistics, and pharmaWhat the DARPA Quantum Benchmarking Initiative means for tenant selection and validationWhy roughly two-thirds of future quantum industry jobs may require a bachelor's degree or less — and what that means for workforce development on a former industrial siteHow the Duality Accelerator, Chicago Quantum Exchange, and Polsky Center create a pipeline from early-stage startups to scale-up tenantsWhy the convergence of physics, engineering, and computer science — all housed in one college at UIUC — is accelerating quantum's transition from science to engineeringResources & LinksGuest LinksHarley Johnson — Professor, University of Illinois Urbana-Champaign, Department of Mechanical Science and Engineering and Materials Science Illinois Quantum and Microelectronics Park (IQMP)Organizations & ProgramsChicago Quantum Exchange (CQE) — regional hub coordinating quantum research, workforce studies, and industry engagement Duality Accelerator — quantum startup accelerator run through the Polsky Center at the University of Chicago Polsky Center for Entrepreneurship and Innovation, University of ChicagoDARPA Quantum Benchmarking Initiative — federal program validating progress toward useful quantum computing NSF MRSEC at UIUC — Materials Research Science and Engineering Center focused on electronic and quantum materials Policy & FundingCHIPS and Science Act — federal legislation driving investment in semiconductor and quantum technology manufacturing in the US Companies MentionedPsiQuantum — photonic quantum computing company scaling up at IQMPIBM — anchor tenant at IQMP with longstanding partnership with UIUCKey Quotes & Insights"Help me pick a problem, a topic that is not big now, but would be big in 10 years." — Harley Johnson, on the question he asked his advisor in 1994 that launched his career in quantum materials"When I heard my friends who are experimental physicists say, 'We know how to do it, now it's just an engineering problem,' I said great — now you've thrown down the gauntlet. Let the engineers at it.""Something like two-thirds of the jobs that this industry will eventually create will require a bachelor's degree or less." — On workforce projections from Chicago Quantum Exchange research"Our neighbors and community members are learning about quantum and thinking about how my grandson gets a job in quantum. Because my family, until now, we're steelworkers." — On the community impact of building a quantum park on a former US Steel site"We're seeing a convergence of the great productive academic minds from computer science, engineering, and physics working now on the same problems. I'm not sure we saw that even five years ago."Related EpisodesAlejandra Y. Castillo — Quantum as a Regional Economic Development Engine — Castillo, former Assistant Secretary of Commerce for Economic Development, discusses how quantum technologies fit into federal and state economic strategy through the CHIPS and Science Act, EDA Tech Hubs, and inclusive workforce development. Essential context for understanding the policy and economic framework that IQMP operates within.Martin Laforest — Building Quebec's Quantum Ecosystem — Laforest, partner at Quantacet and advisor to Canada's National Quantum Strategy, traces how Quebec built one of the world's strongest quantum ecosystems through decades of strategic investment — starting with a bet on condensed matter physics in the 1970s. A compelling parallel to the Illinois story and a window into how this pattern is playing out globally.Nadya Mason — Quantum Leadership — Mason, the dean of the Pritzker School of Molecular Engineering at University of Chicago, is a major force on the academic side of the Illinois quantum ecosystem, and has strong views on what's needed in terms of inclusion and education. Calls to ActionIf you're working on quantum scale-up challenges or building a quantum startup approaching the growth stage, explore what IQMP and the Illinois quantum ecosystem offer — from cryogenic facilities to algorithm partnerships to connections with Fortune 500 end users.Subscribe to the NQE Podcast to follow the people and institutions building the infrastructure for quantum computing's next chapter.Share this episode with anyone in economic development, science policy, or workforce planning who wants a concrete example of how quantum investment translate...

In this episode of The Circuit, Ben Bajarin, Jay Goldberg, and Paul Karazuba discuss the current state of the semiconductor industry, focusing on the impact of tariffs, supply chain challenges, and the shift from copper to fiber in networking. They explore the inflection points driving demand for AI compute and the potential for mergers and acquisitions in the sector. The conversation highlights the complexities of navigating geopolitical tensions and the evolving landscape of technology and infrastructure.

In this week's episode of the Seven Figure Consultant Podcast, we're doing something a bit different! My guest Sharath Jeevan, Founder of The Generational Success Lab at Oxford's Said Business School, is interviewing me as we approach the one-year anniversary of my book 'Too Much'. If you've ever felt like your ambition was 'too much' for the world around you, or if you left corporate because you needed a bigger playing field to run on, this conversation is for you. Sharath and I explore how I went from a rebellious teenager who wanted to be a rock star to building a seven-figure consulting business that finally gives me the container I need.  We talk about the corporate exit, the early days of celebrating £3,000 months, and what it really takes to build a business around your zone of genius rather than what you think you're 'supposed' to do.  This is a candid conversation about legacy, ambition and what happens when you finally stop trying to fit into someone else's version of success. In This Episode:  [00:01:33] How Jessica's early ambition and 'too much-ness' shaped her path - and why entrepreneurship became the only container that could hold her [00:05:16] The violin, physics homework, and parental expectations: navigating the gap between what your family wanted and who you actually are [00:10:22] The corporate years at Sony and the moment Jessica realized she'd rather be made redundant than stay - and what came next [00:17:50] Building a £3,000/month business from the attic and how Jessica's husband became her biggest supporter [00:22:49] The pivot moment: when Jessica stopped trying to 'follow the business plan' and started listening to what clients actually needed [00:27:14] Getting past comparisonitis and imposter syndrome and why one client sale fixes most business problems [00:29:34] Reflecting on the book 'Too Much', writing as legacy work, and what's next Key Takeaways:  Entrepreneurship was the only container big enough: If you've always felt restless in corporate, it's not because you're broken. You just need a playing field where you can run as fast as you want without hitting a ceiling. The power of low-volume, high-ticket consulting: One client sale can fix most business problems. Five clients can fix almost everything. This is why we build businesses where you're not making 500 sales just to stay afloat. Your ambition isn't the problem. The context is: Jessica spent years being told she was 'too much'. The breakthrough came when she stopped trying to fit into someone else's version of success and built a business aligned with her actual genius. Quotes:  "Entrepreneurship has been the only thing that I found, the only container that can actually hold me, that doesn't make me feel kind of trapped or restricted and gives me a big playing field where I can run as fast as I want." - Jessica Fearnley "I always try and go with the path of least resistance, keeping the bar as low as it can possibly be, because then it's like, I may as well have a go. And you know, more often than not it goes well and it works." - Jessica Fearnley "I'm really passionate about how we can be intentional about our legacy. You've done that very consciously and deliberately, and I'm very passionate about how we can all try and find that whatever way makes sense for us in our lives as well." - Sharath Jeevan Useful Links Sharath Follow Sharath on LinkedIn Sharath's Website: intrinsic-labs.com Episode 112: Encouraging Yourself to Make a Bigger Impact with Sharath Jeevan Jessica: Buy Jessica's book, Too Much, on Amazon Get in touch with Jessica to discuss your consulting business Leave a rating and review for the Seven Figure Consultant Podcast Connect with Jessica on LinkedIn Guest Bio Sharath is focused on helping Leaders across sectors futureproof success and build intentional legacy, with clients ranging from L'Oreal to the Barbican to the NHS. He's established the Generational Success Lab at Oxford University's Said Business School, where he's exploring how generations can collaborate better to shape a better world. He's the author of two acclaimed leadership books, "Intrinsic" and "Inflection". Sharath is exploring the questions of generational transition through a forthcoming novel and comedy show.

Ari's journey is shaped not just by elite science, AI, and entrepreneurship—but by deeply human inflection points: a lifelong friendship, the perspective gained through parenthood, and the transformative power of love. This conversation explores how freedom to be different, multidisciplinary thinking, and compassion built a technologist who now measures success by impact, service, and meaning—not titles or credentials.00:09- About Ari SmithAri Smith is an accomplished technology leader and AI expert with a foundation in math and computer science from the MIT ecosystem, where he also co-founded and successfully exited a software startup acquired by a major technology company.He has served in senior technical and strategic roles—including as a Solutions Architect at Microsoft and as CTO of an elite AI engineering firm—while developing patented technologies and advising global organizations.Beyond core technology leadership, Ari engages in interdisciplinary initiatives, from sustainable innovation ventures to serving on the board of a major autism advocacy organization, demonstrating his commitment to impactful, human-centered applications of AI. 

Stay informed on current events, visit www.NaturalNews.com - Bright Videos News Introduction and AI Inflection Point (0:10) - BrightVideos.com Platform Overview (1:39) - AI Video Technology and Future Developments (5:23) - Chinese New Year and Gold and Silver Markets (13:02) - Political News and Palantir Hacking Allegations (18:08) - AI Infrastructure and Market Demand (24:46) - Health Ranger Store and Food Testing (31:02) - Dunning Kruger Effect and AI Job Replacement (35:13) - AI's Exponential Growth and Human Replacement (55:06) - AI's Connection to Morphic Fields (1:07:37) - Morphic Fields and AI Intelligence (1:22:07) - Human Cognition and Power Consumption (1:26:36) - AI Efficiency and Future Projections (1:34:01) - Advancements in AI Technology (1:34:21) - Philosophical Implications and AI Capabilities (1:36:59) - Decentralization of Creativity (1:43:49) - Challenges and Opportunities for AI in Media (1:52:37) - Ethical Considerations and Intellectual Property (1:55:34) - The Future of AI in Entertainment (2:11:08) - Impact on Hollywood and the Media Industry (2:23:10) - Hollywood's Fake News and AI's Real Potential (2:23:49) - The Decline of Hollywood and the Rise of AI (2:48:47) - Conservative AI Illiteracy and Job Replacement (2:52:05) - The Role of Religion and Demographics in AI Skepticism (3:07:14) - The Cultural and Educational Barriers to AI Adoption (3:20:39) - The Future of AI and Its Impact on Society (3:36:27) Watch more independent videos at http://www.brighteon.com/channel/hrreport  ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:

In today's episode, JB White examines what he describes as a major geopolitical turning point, anchored by Marco Rubio's 2026 Munich Security Conference speech and its implications for President Trump's broader strategy. He revisits the Molotov-Ribbentrop Pact to frame today's tensions with Russia, China, and NATO, arguing that current events reflect a deliberate global realignment rather than disorder. JB also touches on technological dominance, Bitcoin market dynamics, public-private power structures, and what he views as the enduring thread of American exceptionalism shaping the next phase of global leadership.      

Michelle talks to Rajat on the implications of investors' positioning as global markets enter a more volatile phase where economic data, policy shifts and geopolitical events reshape investor sentiment.You can read our latest Weekly Market View today here.Speakers: Michelle Kam, Investment Strategist,  Standard Chartered Bank Rajat Bhattacharya, Senior Investment Strategist, Standard Chartered Bank For more of our latest market insights, visit Market views on-the-go or subscribe to Standard Chartered Wealth Insights on YouTube.

Points of inflection - walking through seasons of change - best birthday ever and women in medicine leading the way to health. Thanks for being there for the journey!

Pascal Wagner interviews Jon Brooks, who breaks down why today's real estate market is sending mixed signals—and why getting that interpretation wrong can have real financial consequences. Jon explains how decades of falling interest rates created a powerful tailwind for real estate that no longer exists, especially in overbuilt Sunbelt markets like Florida. The conversation explores what's actually breaking versus what's simply slowing down, including rising insurance and tax costs, declining affordability, demographic headwinds, and stalled migration. Jon also shares why he sold his entire personal real estate portfolio, pivoted into private lending, and ultimately shifted capital into equities as risk-return dynamics changed. This matters because many investors are still relying on outdated assumptions about appreciation, cash flow, and long-term demand. Understanding how interest rates, demographics, and market psychology intersect helps investors reassess where risk is no longer being adequately compensated—and how to position capital without relying on the market to “save” them. Jon BrooksCurrent role: Co-Founder, Momentum Realty; Private Lending Fund ManagerBased in: FloridaSay hi to them at: X - https://x.com/jonbrooks YouTube - https://www.youtube.com/@therealjonbrooks Threads - https://www.threads.com/@iamjonbrooks Instagram - instagram.com/iamjonbrooks/?hl=en Facebook - https://www.facebook.com/jon.brooks.12 Substack - jonbrooks.substack.com Visit ⁠www.tribevestisc.com⁠ for more info. Try QUO for free PLUS get 20% off your first 6 months when you go to quo.com/BESTEVER  Join us at Best Ever Conference 2026! Find more info at: https://www.besteverconference.com/  Join the Best Ever Community  The Best Ever Community is live and growing - and we want serious commercial real estate investors like you inside. It's free to join, but you must apply and meet the criteria.  Connect with top operators, LPs, GPs, and more, get real insights, and be part of a curated network built to help you grow. Apply now at⁠ ⁠⁠⁠www.bestevercommunity.com⁠⁠ Podcast production done by⁠ ⁠Outlier Audio⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Hello to you listening in Corning, New York!Coming to you from Whidbey Island, Washington this is Stories From Women Who Walk with 60 Seconds for Wednesdays on Whidbey and your host, Diane Wyzga.One of the first signs of recognition a new mother looks for in her infant is - a smile. Look! She's smiling at me! Yes! Baby sees you. Baby recognizes you.From earliest days we are cued to the smiles of other human beings. Remember what we missed in the COVID time with masks masking our smiles? Sure, we crinkled our eyes to signal a smile but it wasn't the same as receiving a smile from another human. Sometimes the tone of our voice was a good substitute. The “music of the spoken word” stood in for our smile. We did the best we could with what we had.  Like a smile, the "music of the spoken word" brings written text to life with inflection, pause, tone, emphasis, and  cadence. Reading text alone is quick, cheap, and easy but the human voice lends expression and emotional meaning.I create each 60 Seconds episode with you in mind to offer a measure of hope, delight and imagination, as well as thoughts to ponder, stories to share, a practical tip to lighten and brighten your day. Thank you for taking the time to listen to my podcast episodes. My voice is me smiling at you.  You're always welcome: "Come for the stories - Stay for the magic!" Speaking of magic, I hope you'll subscribe, share a 5-star rating and nice review on your social media or podcast channel of choice, bring your friends and rellies, and join us! You will have wonderful company as we continue to walk our lives together. Be sure to stop by my Quarter Moon Story Arts website, check out the Communication Services, email me to arrange a no-obligation Discovery Call, and stay current with me as "Wyzga on Words" on Substack.Stories From Women Who Walk Production TeamPodcaster: Diane F Wyzga & Quarter Moon Story ArtsMusic: Mer's Waltz from Crossing the Waters by Steve Schuch & Night Heron MusicALL content and image © 2019 to Present Quarter Moon Story Arts. All rights reserved.  If you found this podcast episode helpful, please consider sharing and attributing it to Diane Wyzga of Stories From Women Who Walk podcast with a link back to the original source.

AI isn't just another tech cycle. It's colliding with geopolitics, labor markets, crypto, and creator economies all at once. In this episode of the Block Runner Podcast, we break down why the global landscape is shifting faster than most people realize. From delayed tariffs and geopolitical power struggles, to AI-driven job displacement, no-code engineering, and the rise of vibe coding, this conversation explores what actually matters beneath the noise. We connect the dots between AI infrastructure, resource bottlenecks, robotics, and why this moment feels eerily similar to early crypto. Except this time, execution is possible. We also dig into where crypto still fits, how AI agents interact with crypto rails, and why new business models like creator capital markets are emerging. To close it out, we run a live Doom deathmatch on Track to demonstrate peer-to-peer infrastructure in action, then share updates on NAT, community conviction, and why long-term alignment still wins. If you're trying to understand where AI, crypto, and creators intersect next, this episode is for you. Topics: First up, AI, colliding with geopolitics, labor markets, crypto, and creator economies all at once Next, break down why the global landscape is shifting faster than most people realize. and Finally, we run a live Doom deathmatch on Track to demonstrate peer-to-peer infrastructure in action Please like and subscribe on your favorite podcasting app! Sign up for a free newsletter: www.theblockrunner.com Follow us on: Youtube: https://bit.ly/TBlkRnnrYouTube Twitter: bit.ly/TBR-Twitter Telegram: bit.ly/TBR-Telegram Discord: bit.ly/TBR-Discord $NAT Telegram: https://t.me/dmt_nat

In this episode Wilglory Tanjong talks about her experiences at Princeton University and if her Wharton MBA has been worth it. She discusses earlier career pivots and taking a chance as an entrepreneur. She speaks to the creation of Anima Iris, Beyonce wearing her bag, the difficulty in capital raising, and much more!!TIME STAMPS:Start-6:51    Princeton University experience 6:51-12:52    Early career pivots 12:52-14:30    Traveling the continent of Africa 14:30-26:45   Is business school worth it?26:45-38:07   Anima Iris 38:07-47:30    Inflection points for Anima Iris 47:30-55:40    Beyonce wearing Anima Iris 55:40-1:03:50   Capital raising journey 1:03:50-End    Entrepreneurship advice CREDITS:Hosted by Folarin OkulajaProduced by Folarin OkulajaEngineered by Folarin OkulajaSubscribe to Go With the Flo on Apple Podcasts, Spotify, or wherever you get your podcasts!https://www.youtube.com/channel/UCeheP4nl7aAFDmC8QgV-LUQhttps://open.spotify.com/show/0TCIEfodZuvVgnOVsho4lj?si=N3Pvw2hpR7u4979mwAZ5lQ&dl_branch=1https://podcasts.apple.com/us/podcast/go-with-the-flo/id1551569516

THE DILEMMA OF BIGNESS Colleague Gary Rivlin. How corporate giants like Google were slowed by their own business models, leading Suleyman to leave for Inflection and eventually Microsoft to bypass startup funding issues. NUMBER 15

Inflection

Topics: (00:00:00) - Intro (00:03:30) - Who are your heroes? (00:09:26) - The infancy and evolution of Athena (00:15:12) - Inflection points (00:18:14) - Jonathan's reasoning for going public with interviews (00:20:08) - How do you pick countries to work in? (00:22:41) - Who is the core Athena customer? (00:28:09) - Jonathan's 6 EAs (00:32:13) - Surprising things Jonathan's delegated (00:35:42) - Broadening your scope of what's possible with assistants (00:42:05) - A day in the life with multiple EAs (00:45:41) - Delegation within EAs (00:50:31) - Family dynamics with EAs (00:54:07) - The 2050 version of Athena Links: Athena - https://www.athena.com/ Rolling Fun — https://www.rolling.fun To support the costs of producing this podcast:  >> Buy a copy of the Navalmanack: www.navalmanack.com/  >> Buy a copy of The Anthology of Balaji: https://balajianthology.com/ >> Sign up for my online course and community about building your Personal Leverage: https://www.ejorgenson.com/leverage  >> Invest in early-stage companies alongside Eric and his partners at Rolling Fun: https://angel.co/v/back/rolling-fun >> Join the free weekly email list at ejorgenson.com/newsletter >> Text the podcast to a friend >> Or at least give the podcast a positive review to help us reach new listeners! We discuss: How Jonathan developed calm under extreme startup pressure Athena's evolution from side hustle to billion-dollar vision Why great delegation is a skill, not magic Surprising personal and family delegation use cases Combining humans and AI for exponential leverage Quotes from Jonathan: “My mind is an inner citadel. I've got a good mind, a wife that loves me, and everything else is gravy.” “I started Athena with the sole goal of generating income for my wife and I to live off of.” “The vision of ​Athena​ is the best human assistants powered by the best AI.” “Humans are good UX. We've evolved to like humans.” “You don't build the first Tesla without a steering wheel.” “We're building something that watches assistants work, not to replace them, but to augment them.” “Delegation is a J-curve. It's slower at first, but compounds.” “The cardinal sin of delegation is thinking, ‘It's faster to do it myself.'” “You can think of an assistant as a cognitive prosthesis.” “Belief is the first limiter. Most people don't believe time freedom is possible.” “Ask yourself: If I had a hundred more hours a week, what would I do?” Important Quotes from the podcast on Business and Entrepreneurship   There is no skill called “business.” Avoid business magazines and business classes. - Naval Ravikant   You have to work up to the point where you can own equity in a business. You could own equity as a small shareholder where you bought stock. You could also own it as an owner where you started the company. Ownership is really important.     Everybody who really makes money at some point owns a piece of a product, a business, or some IP. That can be through stock options if you work at a tech company. That's a fine way to start. 

Hello to you listening in Spokane, Washington!Coming to you from Whidbey Island, Washington this is Stories From Women Who Walk with 60 Seconds for Wednesdays on Whidbey and your host, Diane Wyzga.“I will tell you something about stories, he saidThey aren't just entertainment.Don't be fooled.They are all we have, you see,all we have to fight offillness and death.”   ~ Leslie Marmon Silko, Haida Ceremony [The Golden Spruce by John Vaillant, p. 145]Haida NationI may be an old fashioned storyteller clinging to the oral tradition, especially when working with your narratives that function as origin stories, creation myths, messages of all kinds to be seen, heard, understood, repeated and followed, as well as cautions for the young and memories for the elders. Why do I insist on the music of the spoken word? Because that's where the magic happens: at the intersection of the story, the listener, and the teller's voice with its cadence, tone, inflection, repetition, pacing, and energy.So much gets lost in translation to the printed page. What we yearn for without even knowing it is human connection. My clients learn how to connect with their stories and with themselves to be in better service to their purpose.Question: What would you like to learn about the power of story? When you're ready I can help.  Reach out by email => info@quartermoonstoryarts.net OR r arrange a no-obligation Discovery Call You're always welcome: "Come for the stories - Stay for the magic!" Speaking of magic, I hope you'll subscribe, share a 5-star rating and nice review on your social media or podcast channel of choice, bring your friends and rellies, and join us! You will have wonderful company as we continue to walk our lives together. Be sure to stop by my Quarter Moon Story Arts website, arrange a no-obligation Discovery Call, and stay current with me as "Wyzga on Words" on Substack.Stories From Women Who Walk Production TeamPodcaster: Diane F Wyzga & Quarter Moon Story ArtsMusic: Mer's Waltz from Crossing the Waters by Steve Schuch & Night Heron MusicALL content and image © 2019 to Present Quarter Moon Story Arts. All rights reserved.  If you found this podcast episode helpful, please consider sharing and attributing it to Diane Wyzga of Stories From Women Who Walk podcast with a link back to the original source.

On this special segment of The Full Ratchet, the following Investors are featured: Jon Terbell and Ted Clark of FourBridge Partners Lara Banks of Makena Capital Management Jim Tananbaum of Foresite Capital We discuss major conflicts that guests have faced and how they resolved them. The host of The Full Ratchet is Nick Moran of New Stack Ventures, a venture capital firm committed to investing in founders outside of the Bay Area. We're proud to partner with Ramp, the modern finance automation platform. Book a demo and get $150—no strings attached.   Want to keep up to date with The Full Ratchet? Follow us on social. You can learn more about New Stack Ventures by visiting our LinkedIn and Twitter.

Ruslan Belkin (Head of Platform Engineering @ Inflection AI) joins us to deconstruct fundamental shifts in engineering leadership. We explore the future of user interfaces, his “sci-fi” approach to establish & test product vision, & how to leverage “investor decks” for better decision-making and project validation. Ruslan also dives into the complexities of building emotional intelligence into AI systems, cultivating an outcome-oriented engineering culture & avoiding process traps. Plus, we discuss how to keep up with the velocity of change (including when new research necessitates a major pivot), synthetic data & the future of data as a defensibility strategy, & why agent reliability is the massive opportunity ahead. ABOUT RUSLAN BELKINRuslan Belkin joined Inflection after co-founding Jelled.ai—acquired by Inflection in 2024—and previously served as CTO of Nauto. Earlier in his career, Ruslan held senior engineering roles at Twitter, LinkedIn, Netscape, and other pioneering Silicon-Valley companies, bringing more than two decades of experience at the intersection of data platforms and machine learning. SHOW NOTES:How leading engineering teams is evolving: Moving from code as the source of truth to specs/documentation as the source of truth (2:44)Why an eng org's good hygiene / health will create better output (5:12)A framework for product vision: Envisioning the future "viscerally" like a sci-fi novel, stress-testing assumptions, and focusing smart people on the problem (9:04)Hiring in the modern era: Why software engineering is becoming "tooling and data engineering" and the importance of hiring for openness to new research (18:20)Gen Z vs. Millennial engineers: Ruslan's observation that Gen Z is more outcome-oriented and has a lower tolerance for "corporate euphemisms." (22:24)Ruslan's favorite frameworks for effective decision making: Using an "investment deck" to validate projects, avoid disbelief and lack of focus. (25:19)Keeping up with the velocity of change: How to curate research inputs and determine when a new paper (like DeepSeek) requires a strategic pivot. (32:57)The new burden of leadership: Why the velocity of AI requires leaders to be "right more often" and how to use models to increase research rigor. (36:27)The "Data Wall" and Synthetic Data: Why we have hit the wall for text data and how synthetic data generation loops will drive the next wave of defensibility. (41:35)The "March of 9s": Analyzing the trajectory of the AI market and why increasing agent reliability is the massive opportunity ahead. (46:25)Rapid fire questions (48:18) LINKS AND RESOURCESRuslan's Talk at ELC Annual 2025The War of Art - Steven Pressfield's guide to inspire and support those who struggle to express their creativity. Pressfield believes that “resistance” is the greatest enemy, and he offers many unique and helpful ways to overcome it.A Brief History of Intelligence: Evolution, AI, and the Five Breakthroughs That Made Our Brains - Artificial intelligence entrepreneur Max Bennett chronicles the five “breakthroughs” in the evolution of human intelligence and reveals what brains of the past can tell us about the AI of tomorrow. This episode wouldn't have been possible without the help of our incredible production team:Patrick Gallagher - Producer & Co-HostJerry Li - Co-HostNoah Olberding - Associate Producer, Audio & Video Editor https://www.linkedin.com/in/noah-olberding/Dan Overheim - Audio Engineer, Dan's also an avid 3D printer - https://www.bnd3d.com/Ellie Coggins Angus - Copywriter, Check out her other work at https://elliecoggins.com/about/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

“We are more than 10x safer on many key safety metrics than an average human driver” says Saswat Panigrahi, Waymo chief product officer. Saswat joins Bloomberg Intelligence's Mandeep Singh to talk about the inflection in autonomous driving and how Waymo plans to scale across more cities. From the sensors used in Waymo's AVs, the evolution of its driver system and expansion of its partnerships, the discussion focuses on opportunities and remaining challenges around the rollout of AVs.

When you're running a large industrial operation, tracking all of the elements of your process to know where they are and what they're doing in real-time, can be a huge challenge. Today, we're spotlighting a company whose revolutionary platform can help solve that problem. Ed Nabrotzky is the CEO and co-founder of Dot Ai, a company specializing in industrial asset intelligence solutions. Ed brings with him over 25 years of experience in technology development, and has held executive leadership roles at large public enterprises, including Molex and Panasonic.  Ed joins us to discuss Dot Ai's competitive advantage, how AI is changing the game when it comes to asset intelligence, and how their tech helps make companies more efficient.  Highlights:What Dot Ai does (1:53)The gap in the market (2:25)The customers (3:21)Inflection point (4:01)The current emphasis asset intelligence (5:51)ROI (7:09)The Dot Ai platform (8:36)Data Security (12:04)Meeting Unique Client Needs (13:25)R&D (14:40)Puerto Rico Manufacturing (16:15)SPAC (18:49)Forces reshaping supply chains (22:59)Misconceptions about automated asset tracking (25:04)Future outlook (26:10) Links:Ed's LinkedInDot Ai LinkedInDot Ai WebsiteICR LinkedInICR TwitterICR Website Feedback:If you have questions about the show, or have a topic in mind you'd like discussed in future episodes, email our producer, joe@lowerstreet.co.

What if you could know the true age of your brain—and start reversing it today?On this electrifying episode of Thrive LouD with Lou Diamond, recorded live at the Global Passion Project in Southampton, you'll get an insider's look at the breakthrough technologies—and bold thinkers—reshaping our future of health, longevity, and social impact.Lou sits down with a stellar lineup, including Dr. Ramses Alcaide, CEO of Neurable, who unveils how wearable brain-sensing headphones could soon make brain health measurements as common as step counters. Hear firsthand accounts from athletes concerned about cognitive decline, how new brain tech works for real users, and why investors like Peter Thiel, Chris Sacca, and Merck are betting big on brain longevity.Then, XPRIZE's Jason Bateman joins to pull back the curtain on the world's most audacious innovation prizes—from a $101M longevity award to wild carbon-capture ideas like artificial whale poop. Jason argues the biggest problems—like tribalism and the digital divide—need both competitive fire and courageous community to solve.The conversation turns to a dynamic panel with Dr. Jerome Corsi, Dr. Raj Kumar, Josh Rubin, and FDA legal expert Mike Druckman, who reveal how the pandemic, personal experience, and the hunger for systemic change are fueling a revolution in healthcare, data, and investment.If you're ready to meet the visionaries and game-changers shaping tomorrow—and learn what YOU can do about it—this is an episode you can't miss.Timestamped Overview:00:00 – Introduction Setting the scene for the Global Passion Project episodes01:01 – Dr. Ramses Alcaide shares how Neurable's brain-sensing technology is set to change healthcare (and everyday wearables)03:35 – Addressing privacy, safety, and real-world impact of brain data04:45 – Use case: Early detection of neurodegenerative conditions for athletes & those with family risks05:16 – Investors backing brain longevity and the growth of wearable brain tech06:15 – Partnering with the Department of Defense to protect soldiers' brain health07:27 – Scaling to military and commercial markets; 14 years of research brought to market 08:22 – What Dr. Ramses takes away from the Global Passion Project: Purpose, passion, and legacy09:09 – Where to find Neurable and connect with Dr. Ramses online09:50 – Jason Bateman of XPRIZE: Solving billion-scale challenges with multimillion-dollar prizes10:43 – Longevity, AI-driven education, space innovation, climate action, and wild ideas like artificial whale poop for carbon capture12:29 – The surprising origins of XPRIZE and how competition fuels innovation14:05 – Insights from the event: Harnessing capital, competition, and visionary philanthropy17:07 – Jason's biggest issue to solve: The digital divide and loss of empathy online18:50 – XPRIZE's next moonshots—like decoding the ovary's health signals21:49 – Jason's dream location: Bondi Beach, Australia22:30 – Panel intros: Dr. Jerome Corsi, Dr. Raj Kumar, Josh Rubin, and Mike Druckman reveal their personal missions and expertise26:43 – What's resonating at the event: Investment optimism and diverse passion for impact27:21 – Panel insights: Fusing expertise, diverse backgrounds, and hunger for change in healthcare28:20 – Dr. Raj's call to action: We need a little more anger and drive to change healthcare for all30:07 – Dr. Corsi: The role of global partnerships and funding to transform care30:56 – Panel contact details and their organizations for listeners and would-be collaborators34:27 – One-word summaries of the event: Inflection, Transformation, Loyalty, Spectacular 34:41 – Closing notes and where to connect with Thrive Loud and Lou Diamond

Apply to the Coaching for Leaders Academy by Friday, September 12th. In this episode, Dave shares five ways to help leaders thrive through inflection points, including: Redirect vs. respond Set team norms Ask a second question Picture tomorrow's commitment today Hold a funeral