Podcasts about Molecular biophysics

In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Benjamin Garcia. Dr. Garcia is the Raymond H. Wittcoff Distinguished Professor and Head of the Department of Biochemistry and Molecular Biophysics in the School of Medicine at Washington University in St. Louis. His research interests primarily focus on the development of mass spectrometry-based proteomic approaches for the analysis of post-translational modifications of proteins (PTMs) and modified proteomes. His group specializes in high-throughput and quantitative analysis of many classes of modified proteins, especially epigenetic histone PTMs. He is a prolific author and scientific leader, with an h-index approaching 120. He has received a LOT of awards to date, but we sat down with him at the Eastern Analytical Symposium where he was recognized for his recent EAS Award for Outstanding Achievement in Mass Spectrometry. In the conversation we talk about the origins of Dr. Garcia's interests in analytical science, mass spectrometry, and biomedical research, and he shares his thoughts about the current state and near future for technologies used for biomolecule separations including peptides, proteins, and oligonucleotides. We also discuss Dr. Garcia's highly impactful efforts to promote participation in the analytical sciences by people from all backgrounds, and he shares some thoughts about the “to-do list” for his upcoming term as chair of the ACS Division of Analytical Chemistry.

Welcome to The Coaching Lab's 'Dopamine Unplugged' episode, where we dive into the fascinating world of dopamine—our brain's supposed superstar neurotransmitter! Is it really the 'happiness chemical,' or are there more nuanced truths behind its role in motivation and behavior? Today we'll be debunking common myths, explore the latest research, and uncover how understanding dopamine can empower us to create healthier habits and make lasting change. Whether you're a neuroscience enthusiast or just curious about how your brain works, we've got something for everyone. Today's guest, Dr. Talia Lerner, will be our guide through today's unplugging process. She is an Associate Professor in the Departments of Neuroscience and Psychiatry & Behavioral Sciences at Northwestern University. She earned her Bachelor of Science degrees in Molecular Biophysics and Biochemistry from Yale University, her Ph.D. in Neuroscience from UCSF, and completed her postdoctoral work at Stanford University. It took us almost 2 years to tee up this interview with Dr. Lerner, and I think you'll discover it was well worth the wait!Looking for weekly tips, tricks and turbo boosts to enhance your life? Sign up for the CATALYST COMPASS here, a brief weekly compilation of ideas, evidence-based concepts and encouragement to improve your personal and professional life! Info re earning your health & wellness coaching certification, annual Rocky Mountain Coaching Retreat & Symposium & more via https://www.catalystcoachinginstitute.com/ Best-in-class coaching for Employers, EAPs & wellness providers https://catalystcoaching360.com/ YouTube Coaching Channel https://www.youtube.com/c/CoachingChannel Contact us: Results@CatalystCoaching360.comTwitter: @Catalyst2ThriveWebsite: CatalystCoaching360.comIf you are a current or future health & wellness coach, please check out our Health & Wellness Coaching Community on Facebook: https://www.facebook.com/groups/278207545599218. This is a wonderful group if you are looking for encouragement, ideas, resources and more.

BUFFALO, NY- October 21, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on October 1, 2024, entitled, “Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition.” As highlighted in the abstract, monoclonal antibody therapies for cancer have shown extraordinary clinical success in recent years. However, these strategies are primarily limited to targeting specific cell surface antigens, despite many disease targets being located intracellularly. In their paper, researchers Madison Rackear, Elias Quijano, Zaira Ianniello, Daniel A. Colón-Ríos, Adam Krysztofiak, Rashed Abdullah, Yanfeng Liu, Faye A. Rogers, Dale L. Ludwig, Rohini Dwivedi, Franziska Bleichert, and Peter M. Glazer from the Departments of Therapeutic Radiology and Genetics at Yale University School of Medicine, Gennao Bio, and the Department of Molecular Biophysics and Biochemistry at Yale University report on the humanization of the full-length, nucleic acid-binding monoclonal lupus-derived autoantibody 3E10, which exhibits a novel mechanism for cell penetration and tumor-specific targeting. The authors compare humanized variants of 3E10 and demonstrate that cell uptake relies on the nucleoside transporter ENT2. They also find that faster cell uptake and superior in vivo tumor targeting are associated with higher affinity nucleic acid binding. “We show that one human variant retains the ability of the parental 3E10 to bind RAD51, serving as a synthetically lethal inhibitor of homology-directed repair in vitro.” DOI - https://doi.org/10.18632/oncotarget.28651 Correspondence to - Peter M. Glazer - peter.glazer@yale.edu Video short - https://www.youtube.com/watch?v=sTHjJ0Qq0YQ Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28651 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, 3E10, cell penetration, nucleic acid binding, nucleic acid delivery, RAD51 About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

This week, we're presenting stories from scientists who faced unusually difficult paths to science. We all know it's hard work to become a scientist. But for some folks, even getting to that point where you can pursue your science education can seem like an impossible dream. Part 1: When Evelyn Valdez-Ward discovers that she's undocumented, she fears her dreams of becoming a scientist are over.  Part 2: Samuel Achilefu's experiences growing up during the Nigerian Civil War inspire his passion for science.  Evelyn Valdez-Ward is an undocumented, Latina, scientist and PhD student at the University of California, Irvine. For her thesis, she studies the impact of California's drought on the ways that plants and their soil microbes (fungi and bacteria in the soil) communicate and interact with one another. In addition to doing research, she's extremely passionate about advocating for undocumented students in STEM. She recently published her story "I'm an undocumented scientist fighting for my Dream" in Science, and was invited to speak at the March for Science rally in DC to advocate for Dreamers in STEM. She has been awarded a UCI's Dynamic Womxn's Award for Outstanding Social Justice Activist, and the Svetlana Bersahdsky Graduate Student Award for her lobbying and advocacy efforts. She plans to continue lobbying and fighting for her undocumented community after graduating, and work in science policy, where she can continue to advocate for both science and minorities in STEM. Originally from Nigeria, Samuel Achilefu is the Michel M. Ter-Pogossian Professor of Radiology at Washington University School of Medicine. He also holds joint appointments as a Professor in Medicine, Biochemistry & Molecular Biophysics, and Biomedical Engineering and serves as the Chief of the Optical Radiology Laboratory (ORL), Director of the Molecular Imaging Center, Director of the Center for Multiple Myeloma Nanotherapy, and a co-leader of the Oncologic Imaging Program of the Siteman Cancer Center. His lab harnesses the power of light to develop methods for understanding, diagnosing and treating human diseases and is made up of biologists, chemists, engineers, medical scientists and physicists. He enjoys biking, playing tennis, and travelling. Samuel lives with his wife and they have two college-aged children. Learn more about your ad choices. Visit megaphone.fm/adchoices

ACCME President and CEO Graham McMahon, MD, MMSc, welcomes Dr. Kristina H. Petersen to the podcast for a discussion about accessibility in healthcare and healthcare continung education. Formerly of New York Medical College, Dr. Kristina H. Petersen is now Assistant Dean of Student Success & Access and Associate Professor of Biochemistry & Molecular Biophysics at Washington University in St. Louis School of Medicine. Her scholarly work primarily focuses on inclusive instruction, course and assessment accessibility, and creating curriculum to teach clinicians about persons with disabilities. In 2022, she received an award for Excellence in Scholarly Work from the Coalition for Disability Access in Health Science Education and the AAMC/Alpha Omega Alpha Robert J. Glaser Distinguished Teaching Award. She is currently an Alpha Omega Alpha Fellow in Leadership.

Dr. Faraz Harsini has been advocating for animal rights for over a decade. He is the CEO and founder of Allied Scholars for Animal Protection (ASAP), a non-profit organization that supports students who are interested in advocating for animal protection and pursuing careers that can make a difference.   He is also a Bioprocessing Senior Scientist at the Good Food Institute, where he works on advancing scientific and technological methods to produce alternative proteins on a large scale. Dr. Harsini's educational background includes a Bachelor's degree in chemical engineering, with a focus on process design and nanobiotechnology. He also has a Master's degree in biotechnology and cancer research, as well as a PhD in Cell Physiology and Molecular Biophysics. Before joining GFI, he worked in the biopharmaceutical industry, developing therapeutic proteins for diseases such as Covid19, influenza, cancer, and inflammatory diseases. Dr. Harsini collaborates with organizations like PCRM to promote alternatives to animal testing and to combat animal exploitation. He speaks at colleges about his personal experience as an immigrant, a first-generation college student, and a member of the LGBT community, connecting the oppression of animals to other forms of oppression. Dr. Harsini believes that the root cause of many global issues affecting humans and animals is linked to the food system. Therefore, he aims to change the food system through his work at GFI and to train and support students to become future leaders in animal protection through ASAP. LINKS: alliedscholars.org instagram.com/alliedscholars/ gfi.org

This podcast format is inspired by the Charles Dicken's novella “A Christmas Carol” whereby Phil Jeffrey (Bicycle Therapeutics), Beth Williamson (UCB) and Daniel Price (Nimbus) discuss DMPK Past, Present and Future with Scott.  Key elements discussed include the evolution of DMPK as a predictive discipline that links helps the chemistry of drug design with the biology of drug disposition and effect.The episode addresses the following questions:The founding names and principles of DMPK and the emergence of Discovery DMPKToday's use of technologies and in silico modelling and DMPK's role in the 3 pillars/5Rs and PK/PD The outlook for better prediction with advances in AI/MLSpeakers:Phil Jeffrey - Senior Vice President of Preclinical Development at Bicycle TherapeuticsPhil Jeffrey is now semi-retired after contributing to DMPK for over 35 years in the pharmaceutical industry.  Most recently, Phil was Senior Vice President of Preclinical Development at Bicycle Therapeutics and previously has held positions at Pfizer, GlaxoSmithKline, SmithKline Beecham and The Upjohn Company.  Phil is a longstanding contributor the Society for Medicines Research and is an Honorary Professor at the William Harvey Research Institute, Queen Mary University of London.  Phil has a wide breadth of experience across DMPK from, Drug Discovery and early lead optimisation through to clinical proof of mechanism and proof of concept across a wide variety therapeutic areas and drug modalities and made significant contributions to the advancement of understanding the CNS penetration of drugs into the brain. Beth Williamson - Head of ADME in the DMPK group at UCBBeth graduated with a PhD in Pharmacology from the University of Liverpool and is now Head of ADME in the DMPK group at UCB where she also represents DMPK on projects throughout discovery and development. Beth's work has focussed on in vitro and in vivo ADME assay optimisation and validation within drug discovery, particularly to address bespoke questions. Beth has worked in the fields of oncology, neurology and immunology. Her main research interests include drug-drug interactions, extrapolation of pre-clinical in vitro and in vivo data for the prediction of human pharmacokinetics and application of AI/ML approaches within DMPK.  Daniel Price - Vice President of Computational Chemistry & Structural Biology at Nimbus TherapeuticsDr. Daniel Price is Vice President of Computational Chemistry & Structural Biology at Nimbus Therapeutics, where he leads a team of internal and external scientists focused on delivering breakthrough medicines through structure-based design, leveraging both physics-based and knowledge-based predictive modeling.  Before joining Nimbus, he spent 16 years at GlaxoSmithKline, where he led a team of computational chemists and data scientists across diverse areas of structure- and ligand-based drug design, high-content screening analytics, predictive ADME, predictive synthesis, and chemogenomics.  He has led drug discovery programs, contributed to 4 clinical candidates, led the development of GSK's first generation R&D data lake, and authored/co-authored 26 publications.  Dr. Price received his undergraduate degree in chemical engineering from University of Colorado at Boulder followed by his Ph.D. in Molecular Biophysics & Biochemistry from Yale University with Prof. Bill Jorgensen.   He completed an NIH postdoctoral fellowship with Prof. Charlie Brooks, III at The Scripps Research Institute prior to joining GSK. Stay tuned for more podcasts in our Pharmaron DMPK Insights Series!

Neste episódio do Podcast CRUZAMENTO, André Correia e Daniel Guedelha dialogam com Luís Oliveira, Senior Associate Director Research Programs na The Michael J. Fox Foundation, abordando a missão inspiradora da fundação, o impacto global das doenças neurodegenerativas em saúde e economia, e estratégias eficazes para mitigar riscos na Doença de Parkinson. Luis Miguel Oliveira is a Senior Associate Director of Research Programs at The Michael J. Fox Foundation and the Founder of v-ATPase Alliance for rare diseases due to v-ATPase defects. Luís is an expert in the field of Parkinson's disease research and investment with more than 15 years of experience in the neurologic diseases space. Currently, he holds the position of Senior Associate Director of Research Programs at The Michael J. Fox Foundation, where he leads various efforts for therapeutic and biomarker development in priority genetic targets in Parkinson's disease accounting for over $30 million in executed projects. Additionally, Luis Miguel Oliveira is a founder of the v-ATPase Alliance, an organization aimed at connecting families affected by rare diseases related to v-ATPase with the research and medical communities to further advance therapeutic development. With a strong commitment to advance novel treatments from the bench to bedside, Luis Miguel Oliveira serves as a Review Editor for Frontiers in Neurology, Neuroscience and Psychiatry, and as an Investment Advisor for Portugal Ventures, where he leverages his expertise to guide investment decisions in promising ventures. Recently, Luis Miguel Oliveira had an integral contribution to a landmark study that validated the first biomarker for Parkinson's disease diagnosis. This significant achievement was reported in Lancet Neurology with broader international media coverage and is changing the Parkinson's research and drug development fields by enabling an objective characterization of the disease based on its biological features. Luis Miguel Oliveira's educational background includes a degree in Biochemistry from the Faculty of Sciences of Lisbon University. He further pursued his academic journey with a PhD in Molecular Biophysics from the same institution. During his postdoctoral research experience, he conducted his studies at renowned institutions such as the Max Planck Institute for Biophysical Chemistry in Germany and Columbia University in New York. Other relevant references | Outras referências relevantes: v-ATPase Alliance (website) The Michael J. Fox Foundation (website) Contacts | Contactos: CruzamentoPodcast.com cruzamentopodcast@gmail.com LinkedIN: Cruzamento Twitter: @cruzamentofm Facebook: @podcastcruzamento Instagram: @cruzamentopodcast YouTube: Podcast Cruzamento

Tune into this exciting conversation with AAM mentor and dedicated animal activist, Dr. Faraz Harsini.Dr. Harsini delves into his history in various social justice movements in his hometown in Iran that led him to the Animal Liberation cause. With a doctorate in Biomedical Sciences focusing on Cell Physiology and Molecular Biophysics and extensive background as a biomedical scientist in pharmaceutical companies,  involvement in clinical trials, and more, Dr. Harsini's expertise has been immensely valuable in advocating for the need to transition away from using animals in biomedical research toward ethical, human-relevant methods. He is currently a Cultivated Meat Bioprocessing Senior Scientist at the Good Food Institute.He is also the Founder and CEO of Allied Scholars for Animal Protection (ASAP), a nonprofit seeking to establish a national network of animal advocate students at universities and empowering them to pursue professional careers where their knowledge and expertise will benefit countless animals.We even talk about his @SelenaGomez tweet that made him go viral on social media AND raised awareness of the importance of respecting and being kind to all species!Check the links below to connect with and learn more about Dr. Harsini's important work and to get involved with Allied Scholars for Animal Protection:Dr. Harsini:WebsiteInstagramTwitterYouTubeTikTokLinkedInASAP:WebsiteInstagramTwitterFacebookYouTubeLinkedInWe hope you enjoy this insightful conversation with the brilliant Dr. Harsini!AAM Linktree (follow us, donate, bookshop, merch store, future events, and more):linktr.ee/animalactivismmentorshipTo support our work monthly: Patreon.com/AnimalActivismMentorshipTo keep up with the podcast, follow @AnimalActivismMentorship on Facebook, Instagram, and Youtube.Join the conversation in the Animal Activism Mentorship Community facebook group.Want to get active for the animals but don't know where to start?Sign up for a free mentor at AnimalActivismMentorship.comPlease remember to rate, review, and subscribe to the podcast!

On today's show, Prof. Xanthé Mallett discusses "Mushroom Murders": Erin Patterson is charged with murdering three people using poisonous mushrooms in Australia after a lunch event. Later, Brian Gregory discusses the Transport Reality Summit UK, challenging Net Zero Targets and advocating motorist freedoms with the Alliance of British Drivers. GUEST 1 OVERVIEW: Dr. Xanthé Mallett, a forensic anthropologist and criminologist, champions justice through DNA identification, bias combat in legal systems, and expert media analysis.  https://www.newcastle.edu.au/profile/xanthe-mallett https://twitter.com/XantheMallett GUEST 2 OVERVIEW: Brian Gregory is the founder of the Alliance of British Drivers. He obtained his MA in Natural Sciences (Chemistry & Molecular Biophysics). He later obtained Masters of Science in Business Studies from Edinburgh University and worked 30 years in sales & marketing for a global titanium pigment producer. His heavy driving over a number of years in his career and the cavalier approach to road safety of officialdom rapidly became a consuming side-interest, resulting in me forming the Association of British Drivers in the early 1990s renamed The Alliance of British Drivers. Brian also developed a strong interest in studying climate and realised like health & safety overreach, climate also was going to be used as an additional stick with which to beat road users over the head.

Pallav Kosuri uses a physics-inspired approach to discover fundamental mechanisms in biology. Pallav was born in Sweden and studied physics at the Royal Institute of Technology in Stockholm.  After a short stint at CERN, he was awarded a Fulbright scholarship to pursue a Ph.D. in Biochemistry and Molecular Biophysics at Columbia University in New York.  As a Ph.D. student in the lab of Dr. Julio M. Fernandez, Pallav co-invented an Atomic Force Microscope (US Patent 9,880,088) that can apply precisely calibrated forces to single protein molecules while measuring their mechanical response. Using this new microscope, he pioneered the use of mechanical force to study how disulfide bonds are formed during protein folding (Cell 2012).He also used this new microscope to investigate the molecular source of muscle elasticity and discovered a novel chemical mechanism for modulation of muscle stiffness (Cell 2014). After graduating, Pallav moved to Harvard University where he did a postdoc in the lab of Dr. Xiaowei Zhuang. At Harvard he invented ORBIT, a method that uses DNA origami to directly measure molecular rotation. Pallav used ORBIT to discover that RNA polymerase rotates in discrete ~35-degree steps during transcription (Nature 2019), and he is now building on this discovery to investigate transcriptional regulation at the single-molecule level.As an Assistant Professor at the Salk Institute, Pallav leads a diverse team of researchers to investigate fundamental principles of function in biomechanical systems, ranging from molecular machines to muscles, and with a focus on the mammalian heart. His group takes a cross-disciplinary approach that relies on innovation in biophysical and computational methods and imaging techniques. As part of these efforts, he is pioneering the use of single-molecule microscopy to map the architecture of the heart. With these studies, his vision is to create a framework for understanding the connections between genetics, structure, and mechanical function of the human body.

On today's show, Brian Gregory delves into a range of topics. First, we'll cover Greta Thunberg's involvement with fossil fuel activists outside JP Morgan in Canary Wharf, following her recent legal charges stemming from a separate demonstration. Later in the program, Joseph will investigate Keir Starmer's party's historic victory, marking their first seat win since the pivotal by-election in 1996. The burning question remains: Does the Conservative Party have a fighting chance in the upcoming election? GUEST 1 OVERVIEW: Brian Gregory is the founder of the Alliance of British Drivers. He obtained his MA in Natural Sciences (Chemistry & Molecular Biophysics). He later obtained Masters of Science in Business Studies from Edinburgh University and worked 30 years in sales & marketing for a global titanium pigment producer. His heavy driving over a number of years in his career and the cavalier approach to road safety of officialdom rapidly became a consuming side-interest, resulting in me forming the Association of British Drivers in the early 1990s renamed The Alliance of British Drivers. Brian also developed a strong interest in studying climate and realised like health & safety overreach, climate also was going to be used as an additional stick with which to beat road users over the head. GUEST 2 OVERVIEW: Joseph Robertson, an accomplished reporter at Epoch Times, is currently based in London.

What is CRISPR?DNA contains the fundamental information about an organism, and is used as an instruction manual to guide organism structure and function. Until CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats) technology was developed by Jennifer Doudna and Emmanuelle Charpentier, editing DNA sequences was very difficult. Here's the short version of the CRISPR process. First, a CRISPR enzyme is guided by an RNA strand to a DNA strand researchers want to edit. The RNA strand guides the enzyme to a specific point, and the enzyme cuts the DNA molecule. This CRISPR process can be used to eliminate DNA strands, as well as to replace DNA strands using other “repair” enzymes. It is a direct way for human beings to alter the planet's biological blueprint, and, accordingly, its impact can be a strong force for change, positive or negative. How can CRISPR be used to fight climate change?CRISPR can be used to edit the genetic sequences of plants so that they capture more carbon during photosynthesis, and store it in the ground long-term. Since around a third of the Earth's land is cropland, CRISPR-modified agriculture could potentially sequester billions of tons of carbon each year. Professor Kris Niyogi at UC Berkeley studies how CRISPR can be used to increase the efficiency of sunlight utilization in plants during photosynthesis. Photosynthesis captures carbon dioxide, and requires sunlight to do so. By not letting any sunlight go to waste, the plant can capture more carbon dioxide from the atmosphere. CRISPR can also be used to create plants with deeper roots, enabling carbon to be stored deeper in the ground. UC Berkeley Professor Peggy Lamaux studies sorghum plants, searching for the genes responsible for sorghum's deep roots. Related genes in rice and wheat could be altered to have deeper roots, like the sorghum plant. And UC Berkeley Professor Jill Banfield studies how plant-microbe interactions can be altered by CRISPR to store more carbon in soil. Soil microbes secrete sticky biopolymers, which can take soil humic substances and lock them with minerals to create long-lasting associations (potentially up to 100 years) that hold carbon. The Banfield lab aims to CRISPR-modify plants so that they chemically “talk” to microbes, emitting chemicals that encourage the microbes to create more “sticky” carbon, rather than carbon that would be emitted into the atmosphere. Who is Kris Niyogi?Kris Niyogi is a Howard Hughes Medical Institute Investigator, a professor in the Department of Plant and Microbial Biology at the University of California, Berkeley, and a faculty scientist in the Molecular Biophysics and Integrated Bioimaging Division at Lawrence Berkeley National Laboratory. The Niyogi Lab studies photosynthetic energy conversion and its regulation in algae and plants. The lab's long-term research goals are to understand how photosynthesis operates, how it is regulated, and how it might be improved to help meet the world's needs for food and fuel. Dr. Niyogi earned his biology PhD from MIT. Further ReadingIn 10 years, CRISPR transformed medicine. Can it now help us deal with climate change? | University of CaliforniaThis scientist thinks she has the key to curb climate change: super plantsSupercharging Plants and Soils to Remove Carbon from the AtmosphereCRISPR-Cas Can Help Reduce Climate ChangeCan we hack DNA in plants to help fight climate change? For a transcript, please visit https://climatebreak.org/using-crispr-to-fight-climate-change-with-professor-kris-niyogi/

Share this episode: https://www.samharris.org/podcasts/making-sense-episodes/337-the-future-of-psychedelic-medicine Sam Harris speaks with Jeannie Fontana and Robin Carhart-Harris about the TREAT Initiative in California and the growing promise of psychedelics for mental health care. Jeannie Fontana, MD, PhD, is a multifaceted leader in healthcare, specializing in Internal Medicine, Environmental Toxicology, and Biochemistry and Molecular Biophysics. She initiated an ALS-focused research team at Sanford Burnham Prebys and established the Cedars-Sinai ALS Center of Excellence, driving policy change and boosting federal funding for ALS research. As a founding trustee of the California Institute for Regenerative Medicine (CIRM), she played a pivotal role in creating the world's largest stem cell granting agency with an $8.5 billion budget. Under her influence, the agency has achieved FDA approvals, fast-track designations, and launched groundbreaking clinical trials. Additionally, CIRM catalyzed the creation of over 55,000 jobs, 50 new companies, and $10 billion in added state revenue. Now, Jeannie is poised to address California's urgent mental health crisis through her role in the TREAT California Initiative. Website: treatcalifornia.org Robin Carhart-Harris, PhD, moved to Imperial College London in 2008 after obtaining a PhD in Psychopharmacology from the University of Bristol. He has designed human brain imaging studies with LSD, psilocybin, MDMA and DMT, and several clinical trials of psilocybin therapy for severe mental illnesses, including 3 key trials in depression plus 2 further trials in anorexia and fibromyalgia syndrome. Dr Carhart-Harris founded the Centre for Psychedelic Research at Imperial College London in April 2019, the first of its kind in the world. In 2020, he was named among the top 31 medical scientists by The Times newspaper. Dr Carhart-Harris became the inaugural Ralph Metzner Distinguished Professor of Neurology and Psychiatry at the University of California San Francisco in 2021, and in the same year, was listed in TIME magazine’s ‘100 Next’ - a list of emerging leaders from around the world who are shaping the future. Website: carhartharrislab.com Twitter: @RCarhartHarris Learning how to train your mind is the single greatest investment you can make in life. That’s why Sam Harris created the Waking Up app. From rational mindfulness practice to lessons on some of life’s most important topics, join Sam as he demystifies the practice of meditation and explores the theory behind it.

On today's show, Brian Gregory delves into Rishi Sunak's decision to extend the ban on internal combustion engines by five years, pushing it back to 2035. Later, Roger Lehet joins us to shed light on the relentless burden of environmental regulations, which have been making life increasingly challenging for an entrepreneur dedicated to ensuring people stay warm and well-fed. GUEST 1 OVERVIEW: Cheryl Gallagher is a professional artist producing Space Art NFTs and is a musician and a video producer. She's also involved with Asgardia The Space Nation as a Minister of Culture. GUEST 2 OVERVIEW: Brian Gregory is founder of the Alliance of British Drivers. He obtained his MA in Natural Sciences (Chemistry & Molecular Biophysics) and later obtained a Masters of Science in Business Studies from Edinburgh University and worked 30 years in sales & marketing for a global titanium pigment producer. His heavy driving over a number of years in his career and the cavalier approach to road safety of officialdom rapidly became a consuming side-interest, resulting in me forming the Association of British Drivers in the early 1990s renamed The Alliance of British Drivers. Brian also developed a strong interest in studying climate and realised like health & safety overreach, climate also was going to be used as an additional stick with which to beat road users over the head. GUEST 3 OVERVIEW: Roger Lehet is an inventor of cutting edge technology wood stoves that output extremely high heat with despite very small size and extra low emissions. His creations are at www.UnforgettableFirellc.com

Dennis Sherwood is a management consultant who specialises in creativity, innovation, and systems thinking. He has a Physics Masters from the University of Cambridge, an MPhil in Molecular Biophysics and Biochemistry from Yale University and a PhD in biology from the University of California in San Diego. After being a consulting partner at Deloitte Haskins + Sells, and Coopers & Lybrand, he became an executive director at Goldman Sachs. He now runs his own business, The Silver Bullet Machine Manufacturing Company Limited, specializing in organizational creativity and innovation. He has been using systems thinking since 1984 and is one of the UK's leading experts. In addition, he has authored 14 books on a variety of subjects, including systems thinking, creativity, innovation, and financial modelling. His most recent book is Missing the Mark: Why so many school exam grades are wrong - and how to get results we can trust - and this is the topic of this episode. LINKS Dennis's website: https://www.silverbulletmachine.com/ Rethinking Education conference - Sat 23rd September, London: https://bit.ly/reconf23 Making Change Stick: https://makingchangestick.co The Rethinking Education podcast is hosted and produced by Dr James Mannion. You can contact him at www.rethinking-ed.org/contact, or via a social platform of your choosing: Twitter: https://www.twitter.com/RethinkingJames Insta: https://www.instagram.com/drjamesmannion LinkedIn: https://www.linkedin.com/in/james-mannion/ SUPPORT THE RETHINKING ED PODCAST: Become a patron: https://www.patreon.com/repod Buy me a coffee: https://www.buymeacoffee.com/repod

Dr. Alexi Nazem is the Co-Founder and Chief Executive Officer for Nomad Health, the leading digital marketplace for temporary healthcare jobs. Through his entrepreneurial ventures and medical expertise, he has grown the company to over 500 employees and raised over $200 million in capital since its founding. Dr. Nazem has more than two decades of experience in the medical and healthcare sector, and remains an active member of the Department of Medicine faculty at Weill Cornell Medicine. Prior to Nomad Health, he served as a Resident Physician at Brigham and Women's Hospital, National Field Manager for the 100,000 Lives Campaign, and was a Clinical Fellow at Harvard Medical School. Dr. Nazem earned his Bachelor's degree in Molecular Biophysics and Biochemistry from Yale University, his medical degree from Yale University School of Medicine and an M.B.A. from Harvard Business School. Learn more about Alexi at https://atchainternational.com/healthcare-and-higher-podcast-ep73-alexi-nazem/ For a complete list of guests and links to past episodes, visit https://atchainternational.com/healthcare-and-higher-podcast/ Are you a healthcare professional or healthcare executive looking to advance your career, build a better brand, or create a leadership legacy? Visit us at https://atchainternational.com to learn how we can help. Follow Healthcare And Higher: - LinkedIn at https://www.linkedin.com/company/the-healthcare-and-higher-podcast - Facebook at https://www.facebook.com/healthcareandhigher Connect with Iqbal on: - Linked at https://www.linkedin.com/in/iqbalatcha/ - Twitter at https://twitter.com/IqbalAtcha1 Join us next week for another exciting episode of the "Healthcare and Higher" podcast! #HealthcareAndHigher #IqbalsInterviews Song Credits: "Life Is A Dream" by Michael Ramir C. "Stay With Me" by Michael Ramir C.

#biotechnology #biohacking #genetics #toctw #podcast Dr. Jo Zayner is a global leader in the BioHacker movement, constantly pushing the boundaries of Science outside traditional environments. They started BioHacking during their Ph.D. in Molecular Biophysics at the University of Chicago, creating The Chromochord in their apartment, the world's first musical instrument that uses engineered protein nanotechnology. After their Ph.D., Jo received a prestigious fellowship to work with NASA's Synthetic Biology program, engineering bacteria to help terraform Mars. Now they are the Founder and CEO of The ODIN. Jo has a number of Scientific publications and awards for their work in protein and genetic engineering and is also recipient of Art awards for creating Speculative Science works that have been featured in museums across the world, including NY MoMA PS1. Their work has been featured in Time, Scientific American, Popular Science, Businessweek, The Verge and NPR, among many others. They enjoy Whiskey and Red Bull, sometimes together. You can find their personal blog at http://josiahzayner.com https://www.linkedin.com/in/jo-zayner https://www.the-odin.com https://amateurgods.substack.com/ https://twitter.com/4LOVofScience

What is CRISPR?DNA contains the fundamental information about an organism, and is used as an instruction manual to guide organism structure and function. Until CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats) technology was developed by Jennifer Doudna and Emmanuelle Charpentier, editing DNA sequences was very difficult. Here's the short version of the CRISPR process. First, a CRISPR enzyme is guided by an RNA strand to a DNA strand researchers want to edit. The RNA strand guides the enzyme to a specific point, and the enzyme cuts the DNA molecule. This CRISPR process can be used to eliminate DNA strands, as well as to replace DNA strands using other “repair” enzymes. It is a direct way for human beings to alter the planet's biological blueprint, and, accordingly, its impact can be a strong force for change, positive or negative. How can CRISPR be used to fight climate change?CRISPR can be used to edit the genetic sequences of plants so that they capture more carbon during photosynthesis, and store it in the ground long-term. Since around a third of the Earth's land is cropland, CRISPR-modified agriculture could potentially sequester billions of tons of carbon each year. Professor Kris Niyogi at UC Berkeley studies how CRISPR can be used to increase the efficiency of sunlight utilization in plants during photosynthesis. Photosynthesis captures carbon dioxide, and requires sunlight to do so. By not letting any sunlight go to waste, the plant can capture more carbon dioxide from the atmosphere. CRISPR can also be used to create plants with deeper roots, enabling carbon to be stored deeper in the ground. UC Berkeley Professor Peggy Lamaux studies sorghum plants, searching for the genes responsible for sorghum's deep roots. Related genes in rice and wheat could be altered to have deeper roots, like the sorghum plant. And UC Berkeley Professor Jill Banfield studies how plant-microbe interactions can be altered by CRISPR to store more carbon in soil. Soil microbes secrete sticky biopolymers, which can take soil humic substances and lock them with minerals to create long-lasting associations (potentially up to 100 years) that hold carbon. The Banfield lab aims to CRISPR-modify plants so that they chemically “talk” to microbes, emitting chemicals that encourage the microbes to create more “sticky” carbon, rather than carbon that would be emitted into the atmosphere. Who is Kris Niyogi?Kris Niyogi is a Howard Hughes Medical Institute Investigator, a professor in the Department of Plant and Microbial Biology at the University of California, Berkeley, and a faculty scientist in the Molecular Biophysics and Integrated Bioimaging Division at Lawrence Berkeley National Laboratory. The Niyogi Lab studies photosynthetic energy conversion and its regulation in algae and plants. The lab's long-term research goals are to understand how photosynthesis operates, how it is regulated, and how it might be improved to help meet the world's needs for food and fuel. Dr. Niyogi earned his biology PhD from MIT. Further ReadingIn 10 years, CRISPR transformed medicine. Can it now help us deal with climate change? | University of CaliforniaThis scientist thinks she has the key to curb climate change: super plantsSupercharging Plants and Soils to Remove Carbon from the AtmosphereCRISPR-Cas Can Help Reduce Climate ChangeCan we hack DNA in plants to help fight climate change?

Our new episode features Dr. Jennifer Levin Carter, Managing Director at Sandbox Industries and Blue Venture Fund. She joined the Fund in early 2021. Prior to Sandbox Industries and Blue Venture Fund, Dr. Carter was a Managing Director of JLC Precision Health Strategies. She has been a Board member, advisor, and consultant in multiple precision medicine, healthcare services, digital health, and life science companies, both public and private. Dr. Carter has also been involved in the foundation of several companies. In 2018 she founded TrialzOWN™, a healthcare company in stealth, and was the CEO until its prelaunch acquisition in 2019 by Integral Health, a Flagship Pioneering Company, now known as Valo Health. Prior to this venture, Dr. Carter was the Founder and President of N-of-One®, serving as acting-CEO from 2008 to 2012, and Chief Medical Officer from 2012 until its acquisition by Qiagen in 2019. Prior to the foundation of these companies, Dr. Carter advised several life sciences companies as a consultant and practiced internal medicine at Mount Auburn Hospital in Cambridge, Massachusetts. Dr. Carter has a Bachelor of Science in Molecular Biophysics and Biochemistry from Yale University, an MD from Harvard Medical School, an MPH from Harvard School of Public Health, and an MBA from the Sloan School at MIT.In this episode we discuss with Dr. Carter her career journey, highlighting the several skills and tools she honed along the way, especially as a founder of two healthcare startups. We also talk about the importance of building a great team, how to stay motivated, and how to successfully transition careers. 

Dr. Charles Zuker is a Professor of Biochemistry and Molecular Biophysics and of Neuroscience at Columbia University and a Principal Investigator at Columbia's Zuckerman Institute. Dr. Zuker explains why our sense of taste is so evolutionarily critical to our survival; how taste was fundamentally misunderstood until about 20 years ago; how our stomachs tell our brains to go for real sugar instead of artificial sweeteners; why the Zuckerman Institute and the Jerome L. Greene Science Center is such a fabulous place to study neuroscience; and why the Institute has artists-in-residence working alongside the scientists. Also, the video of controlling thirst in mice using light that is referenced in the podcast can be found here: https://www.youtube.com/watch?v=_z51OGBaWko Note: the Zuckerman Institute's air filtration system is top notch, but caused a hum in the background that we couldn't edit out.

Is Medicine influenced by Philosophy? Enjoy this short session with our special guest Dr Ogan Gurel MD, where he introduces us to the Philosophy of Medicine. For further details please visit mini-md.com. Dr Gurel holds an MD (Alpha Omega Alpha) and MPhil (Biochemistry & Molecular Biophysics) from Columbia University. Earning a BA (cum laude in Biochemical Sciences) at Harvard University. In addition to working as a Chief Science Officer, he runs the popular and highly regarded program called Mini-MD (Mini Medical School). Hosted by lawyer and philosopher, Bianca Rose Phillips.

Meet Dr. Enrique Lin Shiao, a scientist who has recognized that his immigrant experience, and the uncertainty associated with it, has helped him become a better scientist. Dr. Lin Shiao was born in Costa Rica to Taiwanese parents, who prepared him and his siblings to continue pursuing better opportunities in places beyond their native country.  He embarked on an immigration journey to pursue academic opportunities, which led him to live in Germany, the U.K, and multiple cities in the U.S. His experiences living in various countries helped him become comfortable with uncertainty, which came in handy when pursuing his PhD in Molecular Biophysics and Biochemistry, because the path to becoming a doctor is full of uncertainties.  Dr. Lin Shiao's experience in the U.S. has helped him embrace his Asian identity even more than before. He carries his Asian and Latin roots wherever he goes, and tries to help and represent both communities as best he can. In fact, Dr. Lin Shiao played a pivotal role during the COVID-19 pandemic that extolled both cultures. He helped develop early stage diagnostics at Berkeley University that were used to test first responders, and the adjacent communities being affected by the virus. Unfortunately, being a person of Latinx and Asian descent has not been easy in the last 6 years. First due to the dangerous rhetoric used to refer to latinx people during the 2016 election, and most recently, due to the unfounded acts of hate directed towards the Asian community, as a result of the words chosen by our highest officials to refer to the coronavirus.  Dr. Lin Shiao has also worked to contrast such harmful narratives by co-creating a podcast called Caminos en Ciencia, which highlights the careers of Latinx scientists. He also hopes that the activism of the last couple of years, such as the Stop Asian Hate movement, leads to meaningful change in our society.  Leave a review:  Apple: https://podcasts.apple.com/us/podcast/latinx-can/id1524232753  Podchaser: https://www.podchaser.com/podcasts/latinx-can-1354080

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with David Katz, Founder & CSO at Sparrow Pharmaceuticals, Inc.Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with David, covering: The contrast of developing new drugs and running clinical trials in a big pharma versus his journey as the founder of a virtual biopharma company. What life really looks like and skills you have to develop in a firm developing novel, targeted therapies to address unmet patient needs. Some of the options, decisions and pathways to commercialization that a Phase 2 biopharma business has to consider. The inspiration, leadership learnings and brand influence of a famous Hollywood character. Prior to founding Sparrow, David was a pharmaceutical R&D leader at Abbott and AbbVie, where he led clinical development and drug discovery teams, and was a personalized medicine pioneer. David is dedicated to the mentorship of the next generation of life sciences entrepreneurs, currently as an entrepreneur-in-residence at Oregon Health & Science University. He held post-doctoral fellowships in immunology at the Universities of Chicago and Michigan, earned MPhil and PhD degrees in Molecular Biophysics and Biochemistry from Yale University, and is an alumnus of Pomona College (BA, Chemistry). David has published over 50 peer-reviewed scientific papers and in his copious spare time, he is actively involved in new play development and is a glass artist. Don't forget to subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is sponsored and funded by ramarketing. An international content, design and digital agency that helps companies in life sciences get noticed.  

Life Under the Sun, Pt. 8 How To Influence People Wisely By Louie Marsh, 10-16-2022   1) I'll keep my mind CLEAR by focusing on Christ.   “1Who is like the wise? And who knows the interpretation of a thing?... (Ecclesiastes 8:1a, ESV)   There's nothing better than being wise. Knowing how to interpret the meaning of life. Eccl. 8: 1a (Mes)   Example of Unclear Mind that needs focus on Christ – The Scales of Good and Evil Cliff Pickover Clifford A. Pickover received his Ph.D. from Yale University's Department of Molecular Biophysics and Biochemistry. He graduated first in his class from Franklin and Marshall College, after completing the four-year undergraduate program in three years. His many books have been translated into Italian, German, Japanese, Brazilian, Chinese, Korean, Portuguese, and Polish. The Good! Buddha Baha'u'llah - Baha'is Dalai Lama Jesus Christ Moses Mother Theresa Abraham Lincoln Martin Luther King Mohandas Gandhi Carl Djerassi -- "Father of the birth control pill."   2) I must have the JOY of the Lord!   “1…A man's wisdom makes his face shine, and the hardness of his face is changed.” (Ecclesiastes 8:1b, ESV)   Joy is the real source of strength – The Joy of the Lord is My Strength!   3) I need to WATCH my mouth!   “2I say: Keep the king's command, because of God's oath to him. 3Be not hasty to go from his presence. Do not take your stand in an evil cause, for he does whatever he pleases. 4For the word of the king is supreme, and who may say to him, “What are you doing?”” (Ecclesiastes 8:2–4, ESV)   Because we have freedom of speech we sometimes tend to think that makes it okay to shoot off our mouths any old time we want too! WRONG!!   4) I'll develop KEEN JUDGEMENT with God's help.   “5Whoever keeps a command will know no evil thing, and the wise heart will know the proper time and the just way. 6For there is a time and a way for everything, although man's trouble lies heavy on him. 7For he does not know what is to be, for who can tell him how it will be?” (Ecclesiastes 8:5–7, ESV)   Yes there's a right time and way for everything, even though, unfortunately, we miss it for the most part. Eccl. 8:6 (Mes)   Good sense of TIMING   Theodore Roosevelt said, “Nine tenths of wisdom is being wise at the right time.”   Mapping out WISE STRATEGY   Knowing what to do is often easy – knowing HOW to do it is another story!   Remaining calm & decisive UNDER PRESSURE.   When in trouble, when in doubt, run in circles, scream and shout! – That's NOT the wise way to influence people!   Possessing INDEPENDENT INTUITION.   Do you think things through and really think about it? Or do you just listen to others, or just think about things the way you always have or were taught in the past? Real leaders, people who are influential think independently and have a good sense of what to do!   5) I should possess a CHRIST-LIKE HUMILITY.   “8No man has power to retain the spirit, or power over the day of death. There is no discharge from war, nor will wickedness deliver those who are given to it.” (Ecclesiastes 8:8, ESV)   We need to be more humble when we deal with everyone, especially people who are hurting and sinning.           How George Washington stopped the Newburgh Conspiracy. In 1783 many officers in the Continental Army were unhappy after the Revolutionary war was over. They hadn't been paid in years and the congress was going to cut their rewards after war too.           Washington heard about this and met with all his officers on March 13, 1783. If he failed to talk them out of it they would march on Congress, force them to pay them –and our country would not be what it is today.           After reasoning with them for a long time Washington hadn't made any head way – and as a last resort decided to read a letter from Congressman Joseph Jones of Virginia. As he pulled out the letter he convinced them in an instant without reading letter.           Did he yell, argue, demand or order? No. Washington, a big, strong, and very formal man let down his guard in an act of humility for just a moment and saved the republic by doing so.           He hesitated and then pulled out his glasses – up to that time only his closest aides had seen him wear them. “Gentleman, You will permit me to put on my spectacles, for I have not only grown gray but almost blind in your service.”           A wave of emotion swept the room, many men openly weeping! Washington read the letter, they voted their thanks to Washington and the matter ended.   6) I won't take UNFAIR ADVANTAGE over others.   “9All this I observed while applying my heart to all that is done under the sun, when man had power over man to his hurt.” (Ecclesiastes 8:9, ESV)   The Clergy sexual abuse epidemic is one example of this – over the last 10 years the number of complaints PER WEEK against Protestant churches for sexual abuse was 70! 25% of those were against the Pastor.   7) I admit that I don't KNOW EVERYTHING only God does!   “16When I applied my heart to know wisdom, and to see the business that is done on earth, how neither day nor night do one's eyes see sleep, 17then I saw all the work of God, that man cannot find out the work that is done under the sun. However much man may toil in seeking, he will not find it out. Even though a wise man claims to know, he cannot find it out.” (Ecclesiastes 8:16–17, ESV)   You and I don't know everything! And guess what? It's no secret to all your friends and family that you don't know everything. So go ahead and admit it – cause we already know it!   3 Mysteries:   1) UNJUST TRIUMPH   “10Then I saw the wicked buried. They used to go in and out of the holy place and were praised in the city where they had done such things. This also is vanity.” (Ecclesiastes 8:10, ESV)   2) UNFAIR CONSEQUENCES   “14There is a vanity that takes place on earth, that there are righteous people to whom it happens according to the deeds of the wicked, and there are wicked people to whom it happens according to the deeds of the righteous. I said that this also is vanity.” (Ecclesiastes 8:14, ESV)   3) UNTIMELY PLEASURE   “15And I commend joy, for man has nothing better under the sun but to eat and drink and be joyful, for this will go with him in his toil through the days of his life that God has given him under the sun.” (Ecclesiastes 8:15, ESV)    

Karl is Fellow of the Royal Society of Arts, and Mentor at Creative Destruction Labs (Said Business School, University of Oxford). He began his career at JPMorgan trading fixed income. In 1996, Karl oversaw Banco Santander's Global Asset-Liability activities in Madrid. In 2001, he returned to London as Global Head of FX for HSBC Asset Management. From 2003, he held Senior Portfolio Manager roles at Brevan Howard, UBS O'Connor, Deutsche Bank's Cross Asset Trading group. In 2012 he joined Barclays Bank Treasury in London as Head of Euro Liquidity Management. In 2017 he joined LPP, Local Pensions Partnership, where he managed the Fixed Income portfolio. In 2018, he was a Participant at the Jackson Hole Economic Symposium. Karl holds two degrees; Physics from Imperial College, London and Molecular Biophysics from University College, University of Oxford. In this podcast we discuss: 1) Capital-ism vs income-ism. 2) The demographic problem. 3) Importance of the scientific method. 4) The end of mean reversion. 5) Investment uncertainty vs risk. 6) The risk of correlation changes. 7) How today's crises are different to GFC. 8) A coming asset crisis. 9) Phase transitions. 10) Central bank, real economy and political regime changes. 11) What the performance of the 60:40 portfolio tells us. 12) Solving for lower future market returns. 13) Demographic – climate change – machine learning shocks. 14) The failure of factor investing. 15) Have a plan A, B and C. 16) Career risk. 17) Books mentioned: The (Mis)Behaviour of Markets (Mandelbrot), The Upside of Down (Homer-Dixon), The Man Who Mistook His Wife for a Hat (Sacks)

We have two special announcements! Very soon we will be celebrating a decade of DNA Today! That's right, we released our first episode on September 1st, 2012. It also coincides with our 200th episode. We want to mark these milestones with you on the show. So send in your favorite episode. You can write it, or better yet, record a 30-60 second voice memo sharing your favorite episode and why you enjoy listening to the show. After all, our podcast would not be possible without you loyal listeners. That's why we want to celebrate together! Send in your voice memo or written message about your fav episode of DNA Today to info@dnapodcast.com. Deadline is August 27th.Thank you to all you listeners for nominating us in the Podcast Awards, you did it! We have officially been nominated. It's year number 6 being nominated and it might be our third time winning the Best Science and Medicine Podcast Award. BUT that's only going to happen if you check your email inbox for an email from The Podcast Awards with the subject line, “Podcast Awards Final Slate Voting”'. If you got this email you are one of the few that were selected to be a voter. It's imperative that you vote! There is a hyperlink to click to get to the voting page. You do have to quickly log back in. Once you do, select DNA Today in the “Science and Medicine category”, select your other fav podcasts and then Hit the “Save Nominations” button. It's that easy. You have until September 10th to do this, but please do it now if you got the email so you don't forget! Our guest this week is Dr. Sam Sternberg, who is a protein-RNA biochemist and CRISPR expert. He runs a research laboratory at Columbia University, where he is an assistant professor in the Department of Biochemistry and Molecular Biophysics. Sam's lab explores the biology of CRISPR-Cas systems and transposable elements, and develops these systems for genome engineering. In addition to publishing his research in leading journals and speaking internationally, Sam remains actively involved in public outreach and ongoing discussions on the ethical issues surrounding genome editing. Together with Nobel Prize winner Jennifer Doudna, he co-authored a popular science book about the discovery, development, and applications of CRISPR technology. Titled A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution, which chronicles the development of CRISPR and explores bioethical aspects of the technology. Their book was a finalist for the Los Angeles Times Book Prize, and The New York Review of Books called it “required reading for every concerned citizen.”Sam received his B.A. in Biochemistry from Columbia University in 2007 and his Ph.D. in Chemistry from the University of California, Berkeley in 2014. He earned graduate student fellowships from the National Science Foundation and the Department of Defense, and was awarded the Scaringe Award from the RNA Society and the Harold Weintraub Graduate Student Award from the Fred Hutchinson Cancer Research Center. Sam worked as a Scientist and Group Leader at Caribou Biosciences before beginning his independent position at Columbia in 2018, and he is the recipient of the NIH Director's New Innovator Award, and is a Sloan Fellow, Pew Biomedical Scholar, and Schaefer Research Scholar.On This Episode We Discuss:Safety, ethical, regulatory considerations for using CRISPR technology Off target effects Working directly with Nobel Prize Winner Dr. Jennifer DoudnaThe 3 major areas of CRISPR applicationsFertility research Animal studies Human genetics Enter our giveaway for your own copy of A Crack In Creation through our social media! For updates on the Sternberg lab, visit their website or follow Sam on Twitter and LinkedIn! You can also read one of his most recent papers on the profiling of CRISPR RNA-guided transposition products here. Stay tuned for the next new episode of DNA Today on August 26th, 2022! New episodes are released on Fridays. In the meantime, you can binge over 195 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Episodes since 2021 are also recorded with video which you can watch on our YouTube channel. DNA Today is hosted and produced by Kira Dineen. Our social media lead is Corinne Merlino. Our video lead is Amanda Andreoli. See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com. PerkinElmer Genomics is a global leader in genetic testing focusing on rare diseases, inherited disorders, newborn screening, and hereditary cancer. Testing services support the full continuum of care from preconception and prenatal to neonatal, pediatric, and adult. Testing options include sequencing for targeted genes, multiple genes, the whole exome or genome, and copy number variations. Using a simple saliva or blood sample, PerkinElmer Genomics answers complex genetic questions that can proactively inform patient care and end the diagnostic odyssey for families. Learn more at PerkinElmerGenomics.com. (SPONSORED)

Why is it important to look at the "MD" as a platform degree? Why should we redefine what entrepreneurship really means? In this episode, we answer all these questions and more, with our guest, Alexander Nazem, MD. Alexander is Co-Founder and CEO of Nomad Health, the first digital marketplace for healthcare jobs, directly connecting physicians, nurses, and medical facilities for healthcare jobs, without the involvement of third-party employment agencies. He has an MD from Yale University, an MBA from HBS, and a BS in Molecular Biophysics & Biochemistry from Yale.

Michael chats with David Katz, chief scientific officer and founder of Sparrow Pharmaceuticals. Prior to founding Sparrow, David was a pharmaceutical R&D leader at Abbott and AbbVie, where he led clinical development and drug discovery teams and was a personalized medicine pioneer. He is currently an entrepreneur-in-residence at Oregon Health & Science University. David held post-doctoral fellowships in immunology at the Universities of Chicago and Michigan and earned a B.A. in Chemistry at Pomona College and a Ph.D. in Molecular Biophysics and Biochemistry from Yale University. In this episode, David discusses the creation of Sparrow, the company's work in developing new medicines for patients who have experienced the effects of excess steroids, and how, in his view, developing drugs is just as much of an art as it is a science. This episode is sponsored by Sparrow Pharmaceuticals, sparrowpharma.com.

On Episode 31 of Black in Science, I sat down with Dr. Jamaine Davis who currently works as an Assistant Professor in the Department of Biochemistry and Cancer Biology at Meharry Medical College. To open, Dr. Davis discusses his childhood while growing up in Long Island, New York. He then segues into his experience as an undergraduate chemical engineering major at Temple University and Drexel University in Philadelphia, Pennsylvania before discussing his transition into the biomedical research field. After sharing the details of his Ph.D dissertation research in the Department of Biochemistry and Molecular Biophysics at the University of Pennsylvania, Dr. Davis delves into the work he did for both of his postdoctoral fellowships at the National Cancer Institute in Maryland. Following this, Dr. Davis describes the Breast cancer and Alzheimer's structural biology and health disparities research his lab focuses on before disclosing his short term and long term goals. To conclude, Dr. Davis shares his feelings on the importance of seeking help, remaining your authentic self and more. If you've enjoyed listening to Dr. Davis' episode of the podcast and wish to contact him with questions, feel free to reach out via: Email: jdavis@mmc.edu Twitter: @jscdavis

Huberman Lab Podcast Notes Key Takeaways The inherent goal of the taste system is to get nutrients to survive – attracted to the ones we need, aversion to the ones that may kill usTaste is predetermined: parts of the brain will experience the full behavioral stimulus, even if activated when only ingesting water“I don't believe obesity is a disease of metabolism, I believe obesity is a disease of brain circuits.” – Dr. Charles ZukerSugar molecules activate the “gut-brain axis” which drives the preference for sugarArtificial sweeteners fail to curb the appetite for sugar because they work on the tongue to recognize sweetsness but do not activate sensors in the gut which satisfy the cravingDiseases of malnutrition today are linked to overnutrition (of processed foods), not the actual absence of foodHighly processed foods highjack the gut-brain axis, continuously reinforcing “wanting”Read the full notes @ podcastnotes.orgMy guest this episode is Dr. Charles Zuker, PhD, Professor of Biochemistry, Molecular Biophysics and Neuroscience at Colombia University and an Investigator with the Howard Hughes Medical Institute. Dr. Zuker is the world's leading expert in the biology of taste, thirst and craving. His laboratory explores the mechanisms of taste perception, focusing on how our conscious and unconscious processing of specific foods and nutrients guide our actions and behaviors. We discuss the neural circuits of taste, the “gut-brain axis,” the basis of food cravings and the key difference between wanting (craving) and liking (perceiving) sugar. We also explore how taste perception relates to specific food satiety, thirst, to our emotions, and expectation. We also consider how sugar containing and highly-processed foods can hijack the natural balance of the taste and digestive systems. Dr. Zuker provides a true masterclass in the biology of taste and perception that ought to be of interest to anyone curious about how the brain works, our motivated behaviors and the neural, chemical perceptual aspects of the mind. Thank you to our sponsors Thesis: https://takethesis.com/huberman ROKA: https://roka.com/huberman Helix Sleep: https://helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Charles Zuker & Taste Perception (00:03:05) Momentous Supplements (00:04:35) Thesis, ROKA, Helix Sleep (00:08:35) Sensory Detection vs. Sensory Perception (00:11:48) Individual Variations within Perception, Color (00:16:20) Perceptions & Behaviors (00:20:19) The 5 Taste Modalities (00:26:18) Aversive Taste, Bitter Taste (00:28:00) Survival-Based & Evolutionary Reasons for Taste Modalities, Taste vs. Flavor (00:30:14) Additional Taste Modalities: Fat & Metallic Perception (00:34:02) Tongue “Taste Map,” Taste Buds & Taste Receptors  (00:39:34) Burning Your Tongue & Perception (00:42:54) The “Meaning” of Taste Stimuli, Sweet vs. Bitter, Valence (00:51:55) Positive vs. Negative Neuronal Activation & Behavior (00:56:16) Acquired Tastes, Conditioned Taste Aversion  (01:01:44) Olfaction (Smell) vs. Taste, Changing Tastes over One's Lifetime (01:09:14) Integration of Odor & Taste, Influence on Behavior & Emotion (01:17:26) Sensitization to Taste, Internal State Modulation, Salt (01:24:05) Taste & Saliva: The Absence of Taste (01:28:10) Sugar & Reward Pleasure Centers; Gut-Brain Axis, Anticipatory Response (01:36:23) Vagus Nerve (01:43:09) Insatiable Sugar Appetite, Liking vs. Wanting, Gut-Brain Axis (01:52:03) Tool: Sugar vs. Artificial Sweeteners, Curbing Appetite (01:54:06) Cravings & Gut-Brain Axis  (01:57:30) Nutrition, Gut-Brain Axis & Changes in Behavior (02:01:53) Fast vs. Slow Signaling & Reinforcement, Highly Processed Foods  (02:10:38) Favorite Foods: Enjoyment, Sensation & Context (02:15:58) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

Huberman Lab Podcast Notes Key Takeaways The inherent goal of the taste system is to get nutrients to survive – attracted to the ones we need, aversion to the ones that may kill usTaste is predetermined: parts of the brain will experience the full behavioral stimulus, even if activated when only ingesting water“I don't believe obesity is a disease of metabolism, I believe obesity is a disease of brain circuits.” – Dr. Charles ZukerSugar molecules activate the “gut-brain axis” which drives the preference for sugarArtificial sweeteners fail to curb the appetite for sugar because they work on the tongue to recognize sweetsness but do not activate sensors in the gut which satisfy the cravingDiseases of malnutrition today are linked to overnutrition (of processed foods), not the actual absence of foodHighly processed foods highjack the gut-brain axis, continuously reinforcing “wanting”Read the full notes @ podcastnotes.orgMy guest this episode is Dr. Charles Zuker, PhD, Professor of Biochemistry, Molecular Biophysics and Neuroscience at Colombia University and an Investigator with the Howard Hughes Medical Institute. Dr. Zuker is the world's leading expert in the biology of taste, thirst and craving. His laboratory explores the mechanisms of taste perception, focusing on how our conscious and unconscious processing of specific foods and nutrients guide our actions and behaviors. We discuss the neural circuits of taste, the “gut-brain axis,” the basis of food cravings and the key difference between wanting (craving) and liking (perceiving) sugar. We also explore how taste perception relates to specific food satiety, thirst, to our emotions, and expectation. We also consider how sugar containing and highly-processed foods can hijack the natural balance of the taste and digestive systems. Dr. Zuker provides a true masterclass in the biology of taste and perception that ought to be of interest to anyone curious about how the brain works, our motivated behaviors and the neural, chemical perceptual aspects of the mind. Thank you to our sponsors Thesis: https://takethesis.com/huberman ROKA: https://roka.com/huberman Helix Sleep: https://helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Charles Zuker & Taste Perception (00:03:05) Momentous Supplements (00:04:35) Thesis, ROKA, Helix Sleep (00:08:35) Sensory Detection vs. Sensory Perception (00:11:48) Individual Variations within Perception, Color (00:16:20) Perceptions & Behaviors (00:20:19) The 5 Taste Modalities (00:26:18) Aversive Taste, Bitter Taste (00:28:00) Survival-Based & Evolutionary Reasons for Taste Modalities, Taste vs. Flavor (00:30:14) Additional Taste Modalities: Fat & Metallic Perception (00:34:02) Tongue “Taste Map,” Taste Buds & Taste Receptors  (00:39:34) Burning Your Tongue & Perception (00:42:54) The “Meaning” of Taste Stimuli, Sweet vs. Bitter, Valence (00:51:55) Positive vs. Negative Neuronal Activation & Behavior (00:56:16) Acquired Tastes, Conditioned Taste Aversion  (01:01:44) Olfaction (Smell) vs. Taste, Changing Tastes over One's Lifetime (01:09:14) Integration of Odor & Taste, Influence on Behavior & Emotion (01:17:26) Sensitization to Taste, Internal State Modulation, Salt (01:24:05) Taste & Saliva: The Absence of Taste (01:28:10) Sugar & Reward Pleasure Centers; Gut-Brain Axis, Anticipatory Response (01:36:23) Vagus Nerve (01:43:09) Insatiable Sugar Appetite, Liking vs. Wanting, Gut-Brain Axis (01:52:03) Tool: Sugar vs. Artificial Sweeteners, Curbing Appetite (01:54:06) Cravings & Gut-Brain Axis  (01:57:30) Nutrition, Gut-Brain Axis & Changes in Behavior (02:01:53) Fast vs. Slow Signaling & Reinforcement, Highly Processed Foods  (02:10:38) Favorite Foods: Enjoyment, Sensation & Context (02:15:58) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

My guest this episode is Dr. Charles Zuker, PhD, Professor of Biochemistry, Molecular Biophysics and Neuroscience at Colombia University and an Investigator with the Howard Hughes Medical Institute. Dr. Zuker is the world's leading expert in the biology of taste, thirst and craving. His laboratory explores the mechanisms of taste perception, focusing on how our conscious and unconscious processing of specific foods and nutrients guide our actions and behaviors. We discuss the neural circuits of taste, the “gut-brain axis,” the basis of food cravings and the key difference between wanting (craving) and liking (perceiving) sugar. We also explore how taste perception relates to specific food satiety, thirst, to our emotions, and expectation. We also consider how sugar containing and highly-processed foods can hijack the natural balance of the taste and digestive systems. Dr. Zuker provides a true masterclass in the biology of taste and perception that ought to be of interest to anyone curious about how the brain works, our motivated behaviors and the neural, chemical perceptual aspects of the mind. Thank you to our sponsors Thesis: https://takethesis.com/huberman ROKA: https://roka.com/huberman Helix Sleep: https://helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Charles Zuker & Taste Perception (00:03:05) Momentous Supplements (00:04:35) Thesis, ROKA, Helix Sleep (00:08:35) Sensory Detection vs. Sensory Perception (00:11:48) Individual Variations within Perception, Color (00:16:20) Perceptions & Behaviors (00:20:19) The 5 Taste Modalities (00:26:18) Aversive Taste, Bitter Taste (00:28:00) Survival-Based & Evolutionary Reasons for Taste Modalities, Taste vs. Flavor (00:30:14) Additional Taste Modalities: Fat & Metallic Perception (00:34:02) Tongue “Taste Map,” Taste Buds & Taste Receptors  (00:39:34) Burning Your Tongue & Perception (00:42:54) The “Meaning” of Taste Stimuli, Sweet vs. Bitter, Valence (00:51:55) Positive vs. Negative Neuronal Activation & Behavior (00:56:16) Acquired Tastes, Conditioned Taste Aversion  (01:01:44) Olfaction (Smell) vs. Taste, Changing Tastes over One's Lifetime (01:09:14) Integration of Odor & Taste, Influence on Behavior & Emotion (01:17:26) Sensitization to Taste, Internal State Modulation, Salt (01:24:05) Taste & Saliva: The Absence of Taste (01:28:10) Sugar & Reward Pleasure Centers; Gut-Brain Axis, Anticipatory Response (01:36:23) Vagus Nerve (01:43:09) Insatiable Sugar Appetite, Liking vs. Wanting, Gut-Brain Axis (01:52:03) Tool: Sugar vs. Artificial Sweeteners, Curbing Appetite (01:54:06) Cravings & Gut-Brain Axis  (01:57:30) Nutrition, Gut-Brain Axis & Changes in Behavior (02:01:53) Fast vs. Slow Signaling & Reinforcement, Highly Processed Foods  (02:10:38) Favorite Foods: Enjoyment, Sensation & Context (02:15:58) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

Becky Pferdehirt is a Partner on the a16z bio investing team. She focuses on early stage companies building technology platforms for therapeutic discovery and development. Prior to joining Andreessen Horowitz, Becky worked at Amgen where she most recently led business development efforts for therapeutic platform partnerships. Before moving to BD Becky was a research scientist in Amgen R&D, focused on cell and gene therapy technology innovation. Becky completed her postdoctoral education at Genentech studying cancer cell biology and proteomics. She holds a PhD in Molecular and Cellular Biology from UC Berkeley and a BS in Biology from MIT.&Seth Lieblich is a Principal on the 8VC Bio Team. Seth came from Amgen where he was in Amgen Business Development's technology group where he was responsible for search & evaluation and transactions for platform technologies across a number of therapeutic and functional areas. Seth was also responsible for strategic academic partnerships across all therapeutic and geographic areas. Prior to Amgen, Seth was at ZS Associates where he led teams engaging in market research, sales force design, and strategy. Prior to ZS Associates, Seth was co-founder and COO of Protomer Technologies, a Pasadena-based biologics startup. Seth received his Ph.D. in Biochemistry and Molecular Biophysics from the California Institute of Technology and holds a B.S and M.S. in Biochemistry from Brandeis University.Thank you for listening!BIOS (@BIOS_Community) unites a community of Life Science innovators dedicated to driving patient impact. Alix Ventures (@AlixVentures) is a San Francisco based venture capital firm supporting early stage Life Science startups engineering biology to create radical advances in human health.Music: Danger Storm by Kevin MacLeod (link & license)

Dr. Cameron Hill from the Randall Centre for Cell and Molecular Biophysics, Kings College London, and Dr. Paul Morgan from the University of Birmingham, United Kingdom, discuss the topic of an editorial that was co-authored by Dr. Hill - along with Dr. Jason Tallis from Coventry University Centre for Sport, School of Life Sciences, Coventry, West Midlands, United Kingdom - and published by Aging (Aging-US) in Volume 11, Issue 8, entitled, “Is obesity a risk factor for skeletal muscle ageing?” DOI - https://doi.org/10.18632/aging.101941 (PDF download) Full text - https://www.aging-us.com/article/101941 Corresponding Author - Cameron Hill - cameron.hill@kcl.ac.uk Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.101941 Keywords - isolated muscles, obesity, sarcopenic obesity, power, force, muscle quality About Aging-US Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at http://www.Aging-US.com​​ and connect with us: SoundCloud - https://soundcloud.com/Aging-Us Facebook - https://www.facebook.com/AgingUS/ Twitter - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/agingus​ LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Aging-US is published by Impact Journals, LLC: http://www.ImpactJournals.com​​ Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM

 In this episode of DanceCast, Silva interviews Magda Kaczmarska, a dancer, researcher, and creative aging teaching artist based in New York City. Magda describes how her path as an immigrant with a background in dance and the sciences shaped her interest in and commitment to community based dance in the field of creative aging.  She revisits how exposure to Dance for PD®, a program by Mark Morris Dance Group for people with Parkinson's led her to eventually leave her research career in pursuit of an MFA in Dance. An injury during grad school reinforced her career focus to expand access to creative aging for all communities. In NYC, she worked with the company Dances for a Variable Population with whom she supported 100s of diverse older adults in exploring their creative expression through movement. Now, as an Atlantic Fellow for Equity in Brain Health, she is working to expand creative aging programs globally, building programs that support brain health across the life span and allying with communities of people living with dementia to amplify their creative voice. She expands on her belief that aging is a lifelong process, and at any point in our lives, our experience that can be translated into creative expression through movement. She invites us to consider and question how better we can support interconnectedness and meaningful creative expression for all as we age.Text by Emmaly WiederholtMagda Kaczmarska received her MFA in Dance Performance and Choreography and her BS in Biochemistry and Molecular Biophysics from the University of Arizona. Magda has dedicated her career to utilizing the vehicle of dance and movement to amplify and support creative community. Her multidisciplinary work leverages a dual background in neuropharmacology and dance to build bridges between seemingly disparate sectors. Through all her work, she seeks to foster safe, creative, and inclusive spaces for discovery, agency and meaning. She believes all of us possess the ability to harness our creative expression to support building meaningful communities around us. As an Atlantic Fellow for Equity in Brain Health at the Global Brain Health Institute, Magda builds collaborations to design and expand access to creative aging programs that support brain health across the lifespan.To learn more about Magda's work, visit magdakaczmarska.com.To read more interesting dance articles visit, stanceondance.comTo learn more about Silva's work at Art Spark Dance visit, bodyshift.org  

One of the positives during the current pandemic is that both healthcare professionals and consumers have made gains in expanding the possibilities of the health curve, in particular with the use of digital technologies related to therapeutic devices, telehealth, and remote monitoring, however, overall health literacy remains an opportunity and is positioned for even more growth. Today's episode gives listeners unique insights into the world of health with a particular focus on health literacy. This episode's guest is Dr. Ogan Gurel, a Chief Science Officer, founder of The Mini Medical School, Mini-MD, and author of Waves, The Book, which is a story that recounts the adventures of the contemplative and idealistic Tomas, a doctor-turned-entrepreneur who's discovered a new technology with both medical and military applications. His experiences span the executive, marketing, clinical and R&D domains, with sector expertise in medical devices, digital health, medical imaging, and biopharma as well as academic research focused on protein electrodynamics and terahertz medicine. He also serves as a venture partner in addition to several academic appointments. Dr. Gurel holds an MD and MPhil in Biochemistry & Molecular Biophysics from Columbia University as well as a Bachelor of Arts in Biochemical Sciences from Harvard, where he conducted research in molecular dynamics with Martin Karplus, who was awarded the 2013 Nobel Prize in Chemistry. For more details visit TechLink Health @ https://www.techlink.health or connect with Dr. Gurel @ https://www.linkedin.com/in/ogangurel/. This episode was hosted by Justine Reiss. If you're a healthcare practitioner or thought leader and interested in leveraging the TechLink Health platform for telehealth, e-consults, or advisory services, feel free to connect with us by visiting our site or downloading the TechLink Health app. iOS - https://apps.apple.com/app/techlink-health/id1492325493 Google Play - https://play.google.com/store/apps/details?id=millennialtech.techlinkhealth

In this episode, I converse with Prof. James Fraser at the University of California, San Francisco. James was an undergraduate at McGill University, where he worked in the lab of Dr. Francois Fagotto on Xenopus developmental biology. As a graduate student, with Tom Alber at UC Berkeley, James established room-temperature X-ray data collection techniques and electron density sampling strategies to define protein conformational ensembles essential for catalysis. Prior to starting an independent position at UCSF, he was a visiting EMBO Short Term Fellow in the lab of Dan Tawfik at the Weizmann Institute of Science in Israel and developed expertise in directed evolution and high-throughput assays of enzymatic or binding activity. In January 2011, James started his independent career as a QB3 at UCSF Fellow affiliated with the Department of Cellular and Molecular Pharmacology. In January 2013, he was appointed as an Assistant Professor in the Department of Bioengineering and Therapeutic Sciences and the California Institute for Quantitative Biosciences (QB3) with promotion to Associate Professor in 2016, and Full Professor in 2020. James is also a Faculty Scientist in the Molecular Biophysics and Integrated Bioimaging Division of Lawrence Berkeley National Lab. The long-term goals of James' research group is to understand how protein conformational ensembles are reshaped by perturbations, such as mutation and ligand binding, and to quantify how these perturbations impact protein function and organismal fitness. To accomplish these goals, they create new computational and biophysical approaches to study how proteins move between different conformational states. Additionally, the group uses two complementary approaches to study the relationship between protein conformational ensembles and function. To dissect consequences of mutations on organismal fitness, they use high-throughput systems biology and biophysical methods to analyze large sets of clinically or biophysically interesting mutations and to improve the ability to engineer new protein functions, they investigate changes to the conformational ensemble as new enzymatic and binding functions emerge from directed evolution studies. We indulge in a fascinating conversation on his enjoyable journey through science and life; foraying into academia from a family of non-academics; the thrill of methods development; the enormous influence of his brilliant mentors, friends, and collaborators; creating a more equitable, open, and just environment in science; and many more things!!

Dr. James Pipas is the Herbert W. and Grace Boyer Chair in Molecular Biology and Professor of Biological Sciences at the University of Pittsburgh. Jim's lab studies how viruses work, how they interact with us, and where they come from. They also use viruses as tools to understand how our own biology works. For example, they study viruses that cause cancer. Outside of science, Jim's passions include entertaining and exploring. He composes music, sings, and produces shows with his brother all over the world. The other activity that brings him great joy is immersing himself in nature in remote forests and mountains. He received his PhD in Molecular Biophysics from Florida State University and completed his postdoctoral training at Baylor College and the John Hopkins School of Medicine. Jim has been a faculty member in the Department of Biological Sciences at the University of Pittsburgh now for over 30 years. Jim joined us for an interview to tell us more about his life and science.

Glenn is a Associate Professor at North Dakota State University with a Ph.D. in Biochemistry and Molecular Biophysics. He also is one of only 134 people to receive the rank of Black Belt from legendary instructor Ralph Castro in the art that he founded. I hope you enjoy his story. Ralph Castro's Shaolin Kenpo Black ... Glenn Dorsam – Shaolin Kenpo Black Belt – Ep27

Scientists speak of those moments of discovery when all their hard work, all their experimenting, and all their trial and error yield sometimes surprising results.  Hosts Judy Muller and George Lewis chat with three noted researchers about how creativity plays a big part in their science.  Our guests are Philip Bevilacqua, Distinguished Professor of Chemistry and Biochemistry and Molecular Biology at Penn State, Scott Showalter, also from Penn State, Professor of Chemistry, Biochemistry and Molecular Biology; and Kathleen Hall, Professor of Biochemistry and Molecular Biophysics at Washington University in St. Louis.  Our panel was part of a series of "Town Talks" in Telluride, recorded before a live audience at the Wilkinson Public Library.

Prologue You've GOT to hear this! This week on the podcast, I invited Martin Zizi of Aerendir, to talk about how we can use technology to not only distinguish between humans and non-humans (bots?) but also how to identify humans with staggering levels of precision - using commonly available and inexpensive components. He's got humor, an eclectic background, and great knowledge of the topic. Join us! Guest Martin Zizi Bio: Dr. Martin Zizi, MD-Ph.D, deep expertise in Molecular Biophysics and Neurosciences. He is one of the Founders & CEO of Aerendir Mobile Inc. He is the inventor of the NeuroPrint®, a cloudless AI-supported neural-tapping technology that can be used for authentication, identification, encryption, secure TLS, and bot segregation. Following his early years in the United States as a Scientist at the Walter Reed Army Institute of Research where he worked on very advanced projects, he had a 20-years dual-track career, leading both academic and strategic projects as a top scientist in 3 fields and was also a Chief Scientific Officer for Belgian DoD. Martin was a sought-after advisor for the Belgian, the EU governments, international organizations (UN) and the industry. Aerendir Mobile Inc. is his second start-up. He was #2 at another start-up in the Medical technology vertical. LinkedIn: https://www.linkedin.com/in/martinzizi/ Twitter: https://twitter.com/MartinZ_uncut Aerendir Mobile, Inc. LinkedIn: https://www.linkedin.com/company/aerendir-mobile-inc Twitter: https://twitter.com/AerendirMobile/ 

Kat speaks with Elspeth Garman (Suffrage Science Life Sciences awardee, 2020), Professor of Molecular Biophysics at the University of Oxford, namesake of the 'Garman limit' and pioneer in X-ray crystallography. Elspeth reveals how her adventures abroad as a teenager landed her with much more than she could have imagined, and the trials and benefits of pivoting from nuclear physics to life sciences.  

Dr. Charles Cockell is a Professor of Astrobiology in the School of Physics and Astronomy at the University of Edinburgh and Director of the UK Centre for Astrobiology. In addition, he is the Founder and Chair of the Earth and Space Foundation and also the Co-Founder, current Board Member, and Past President of the Association of Mars Explorers. Charles has also been elected as an International Fellow of the Explorers Club. His work examines how life has emerged and has persisted on our planet and beyond. One of Charles's favorite things to do when he's not at work is go walking out in the hills and wilderness. It's a great way to clear his mind and enjoy the outdoors. He did his undergraduate training in Biochemistry and Molecular Biology at Bristol University and received his PhD in Molecular Biophysics from the University of Oxford. Prior to joining the faculty at the University of Edinburgh, Charles was a National Academy of Sciences Associate with NASA, a visiting Scholar at both Stanford University and the University of Arizona, a Research Scientist with the British Antarctic Survey, and also Professor of Geomicrobiology at Open University. In this episode, Charles discusses, his life, science, and more.

In this podcast episode, Dr. Cam Sepah interviews the entrepreneur and investor Sebastian Caliri. Sebastian completed a year of the MD program at Stanford University and holds a BS and MS, magna cum laude, in Molecular Biophysics & Biochemistry from Yale University. Sebastian invests in both consumer and enterprise space at 8VC with a focus on healthcare. Timecodes 00:00 Intro 02:50 Why did you decide to invest in Maximus? 05:00 What was your upbringing like? 08:30 What is an elite boarding school like? 11:10 What subjects were you interested in growing up? 13:00 What was it like studying science at Yale? 15:30 Is it necessary to focus just on academics? 20:30 Why did you decide to go to medical school? 22:30 What is Thiel Fellowship? 27:00 What made you decide to drop out of medical school? 32:30 Why did you decide to work with Palantir? 36:00 What was it like working in the startup community? 41:00 Why is it ok to try and figure things out on your own? 43:00 Why it's important to work with people you respect and look up to. 48:00 Knowing what you know now, would you still have taken the same path?

Daniel Griffin, MD, PhD answers questions about misconceptions about children and COVID-19: How common are chronic “long COVID” symptoms in children? Are children less likely than adults to get and spread COVID 19? When are coronavirus vaccines for children going to be authorized? Do kids need to wear masks outside? Tips for parents to navigate school, sports, and summer camp during the pandemic? Should children get a cardiac evaluation before returning to sports if they've had COVID-19? What is multi inflammatory syndrome? Why do kids typically get less severe COVID-19 disease and what can we learn from their immune systems? Dr. Daniel Griffin is an instructor in Clinical Medicine and an associate research scientist in the Department of Biochemistry and Molecular Biophysics at Columbia University. Dr. Griffin is board-certified in Infectious Disease, Co-Host of This Week in Virology, and Co-Founder of Parasites Without Borders. Full Bio: https://asm.org/Biographies/Daniel-Griffin  Parasites Without Borders (A non-profit): https://parasiteswithoutborders.com  This Week in Virology: https://www.microbe.tv/twiv/ Interviewer: Kyle Allred, Physician Assistant, Producer, and Co-Founder of MedCram.com (This interview was recorded on March 17, 2021)

Christina Roman is a sixth year PHD candidate studying Biochemistry and Molecular Biophysics with a focus on RNA structure using x-ray crystallography and protein engineering in Dr. Joseph Piccrili's lab at the University of Chicago. In her spare time, Christina has also been serving as a race and pedagogy graduate coordinator at the University of Chicago helping students, faculty and administrators develop more racially inclusive teaching practices and programming. Before that she served as the president of her local Society for Advancement of Chicanos and Native American's in Science (SACNAS). She also co-founded a graduate student organization called the Graduate Recruitment Initiative Team (GRIT) which seeks to improve the recruitment and retention strategies graduate programs use to recruit and train diverse students.To learn more about Christina's work, you can follow her on Twitter @CR_FabEngineer. Links Christina Roman https://twitter.com/CR_FabEngineer https://www.linkedin.com/in/christina-roman-28a029a8/ Lab Members | Piccirilli Lab (uchicago.edu) https://voices.uchicago.edu/piccirillilab/lab-members/ Grad students DJ Speed and Christina Roman receive HHMI Gilliam Fellowships | UChicago Biosciences https://biosciences.uchicago.edu/news/grad-students-dj-speed-and-christina-roman-receive-hhmi-gilliam-fellowships Graduate students organize to provide face masks and first aid supplies for protesters - UChicago Medicine https://www.uchicagomedicine.org/forefront/news/graduate-students-organize-to-provide-face-masks-and-first-aid-supplies-for-protestors Graduate Recruitment Initiative Team (GRIT) | UChicago Biosciences https://biosciences.uchicago.edu/diversity/grit Graduate Recruitment Initiative Team (GRIT) grows to the PSD and beyond | University of Chicago Department of Chemistry (uchicago.edu) https://biosciences.uchicago.edu/diversity/grit Resources for Black People Experiencing Racial Trauma https://bit.ly/3bzkhsM Anti-racism resources for white people https://bit.ly/35BbYsr How to Be an Anti-Racist - Ibram X. Kendi https://g.co/kgs/9VoZkv White Fragility - Robin DiAngelo https://g.co/kgs/f85K6L Timeline 2:53 - The elevator pitch for Christina's PhD program 5:05 - Why take pics of RNA? 8:32 - Is her research funded by the NIH? 9:05 - Where do you see yourself going with this research? 11:16 - How do you see your work changing our response to future viruses? 14:18 - Why having a better understanding of RNA is so important 15:01 - Did RNA exist before life? 16:05 - John wanders off to the "primordial soup theory." 17:29 - Can we ever watch evolution in a petri dish? 21:33 - Making science research approachable for the general public 22:24 - Christina's work in Diversity, Equality and Inclusion 25:47 - How navigating race in academia became like a second job 28:50 - How is this work changing things for future students? 30:56 - what would a "perfect" academia look like to Christina? 33:40 - What tactics and resources might be useful for diversity training? 34:38 - What would diversity training look like within logic-based subjects? 35:36 - Is there a consistent diversity training manual for professors? 37:04 - Why is talking about race/ diversity in all subjects important? 40:58 - How do we reach people who haven't had the exposure to learn? 42:14 - What can universities do to empower professors? 45:13 - How can prospective students vet schools for diversity? 51:34 - Where does she see this curriculum going? 54:06 - Does she see herself staying involved with this work? 56:20 - Any go-to resources? 1:02:06 - How important is empathy?

This episode features Greg Bowman, Assistant Professor of Biochemistry & Molecular Biophysics at Washington University School of Medicine and Director at Folding@home. Here, they discuss how things have changed in his work to focus on COVID-19 research, how he expects the Folding@home project to progress moving into 2021, and more.

Men have several challenges to face when considering the various treatment options for prostate cancer. One of those challenges is weighing the potential side-effects that come with the therapy. New and innovative technology continues to become available to help in reducing the potential short and long-term side-effects of prostate cancer treatment. Some men who are considering the option of radiation therapy may be candidates for a new method that utilizes a water-based gel to help in reducing the side-effects of the treatment. Stay tuned to find out more! We feel honored to have Dr. Xinglei Shen, a radiation oncologist from the University of Kansas Medical Center, joining us today. Dr. Shen grew up in the Kansas City area. His background includes a Molecular Biophysics and Biochemistry degree from Yale University. He received his Medical Degree at the University of Pittsburgh School of Medicine and completed residency training in Radiation Oncology from Thomas Jefferson University Hospital in Philadelphia, Pennsylvania. Since 2012, he has been an Associate Professor in the department of radiation oncology at the University of Kansas Medical Center and leads the genitourinary service at KU Radiation Oncology. In 2016, he began offering SpaceOAR Hydrogel therapy and was the first provider to offer it in the Kansas City area. Around the same time, he started KU's Stereotactic Body Radiation Therapy Program. Be sure to listen in today to learn about the new water-based gel treatment method for prostate cancer that helps in reducing side-effects. Disclaimer: The Prostate Health Podcast is for informational purposes only. Nothing in this podcast should be construed as medical advice. By listening to the podcast, no physician-patient relationship has been formed. For more information and counseling, you must contact your personal physician or urologist with questions about your unique situation.  Show highlights: Dr. Shen talks about the goals of therapy for prostate cancer. Some of the potential risks men need to consider regarding radiation therapy. Dr. Shen discusses some of the more recent advances in the field of radiation oncology and minimizing the potential toxicity of therapy. Dr. Shen explains what SpaceOAR Hydrogel technology is, and how it works. Dr. Shen explains how the SpaceOAR Hydrogel gets administered. Dr. Shen describes the most appropriate candidates for the SpaceOAR Hydrogel. Some of the reported outcomes so far with SpaceOAR, in terms of the amount of toxicity. The time it takes for the gel to dissolve. The potential risks of SpaceOAR Hydrogel. Links and resources: Follow Dr. Pohlman on Twitter and Instagram - @gpohlmanmd  Get your free What To Expect Guide (or find the link here, on our podcast website)   Join our Facebook group  Follow Dr. Pohlman on Twitter and Instagram  Go to the Prostate Health Academy to sign up for the wait-list for our bonus video content.  About Dr. Xinglei Shen and SpaceOAR Hydrogel

Dr. Yousif Shamoo joins us for a conversation about Rice University's cutting edge innovation in everything that has an enormous impact on your life. Rice is leading the way in the research and development of next generation clean carbon technology, vaccines and antibiotics, and agricultural production that uses less land to feed more people. Dr. Shamoo takes us on a tour of a future brought to you by the world's leading scientists - all located within Houston, TX. Dr. Yousif Shamoo has served as Vice Provost of Research at Rice University since 2014. He was appointed Professor of BioSciences in 2012, and first joined the Rice University faculty in 1998. He served as Rice’s Director of the Institute of BioSciences and Bioengineering from 2008-2014, leading the coordination of interdisciplinary research among Rice faculty. He received his Ph.D. degree in Molecular Biophysics and Biochemistry from Yale University in 1988.

A Nobel Prize. Some would say it represents the pinnacle of scientific achievement in any given field. In this episode, we're lucky enough to be joined by Joachim Frank, one of a very small number of scientists that can say they have won the prestigious award. Joachim was born and educated in Germany, before completing postdoctoral research in the United States and at the Cavendish Laboratory in Cambridge, U.K., where he worked on problems of electron optics and image processing. His current position at Columbia University as a Professor of Biochemistry and Molecular Biophysics and of Biological Sciences, is one that he has held since 2008. In 2017, Joachim recieved the Nobel Prize for Chemistry, alongside his colleagues Jacques Dubochet and Richard Henderson, for the development of cryo-electron microscopy, which both simplifies and improves the imaging of biomolecules. This method moved biochemistry into a new era. Timestamps 00:15 - Who is Joachim Frank? 01:05 - Initial interested in science? 04:34 - A degree in Physics? 06:25 - How do you stumble upon Nobel Prize winning research? 07:30 - The seeds & The process. 16:48 - What are the implications of the work? 21:55 - Receiving a Nobel Prize. 22:48 - Does the prize open doors? 27:35 - Advice for PhD students? 29:50 - What is your favourite book?

Are you a woman of a certain age with any of the following symptoms?  Fatigue, weight gain, fuzzy thinking, anxiety, depression, hair falling out, low libido, problems sleeping?  Maybe your doctor has told you that it’s just your age, and there is nothing you can do about it.  If this sounds familiar, you’ll want to listen to this interview with Dr. Lauren Deville!  Prepare to be inspired and know that there are solutions! Dr Lauren Deville is a graduate of Southwest College of Naturopathic Medicine in Tempe, AZ, and is the owner of Nature Cure Family Health in Tucson, Arizona. She received her BS in Biochemistry and Molecular Biophysics from the University of Arizona. She is the author of The Holistic Gut Prescription and How to Be Healthy: Body, Mind, and Spirit, and the host of the weekly podcast, Christian Natural Health. She writes young adult fiction in her spare time under the pen name C.A. Gray, and maintains an occasionally contentious movie review blogwith her cinephile husband.   https://www.drlaurendeville.com/ Is it time to make some changes in your life? Do you want to stop the madness and get on track with your health? Maybe coaching is right for you. I've helped many people gain their health back over the years, and would love to talk with you. Just reach out with the link below to get on my schedule. From time to time I have openings for new clients and accept them on a first come first serve basis. Book a Discovery Call

Today's episode of Redefining Medicine features Catherine Kodama, MD. At her private clinic, BioAge Health, located in Eagan, Minnesota and serving the Twin Cities, Dr. Kodama uses a personalized approach in a comfortable setting to provide treatment that is designed for each patient. From her own struggles with a serious endocrine disorder, as well as a personal diagnosis of cancer, Dr. Kodama has become a proponent of longevity and wellness through five important pillars of health: eating healthy, exercising regularly, optimizing hormone balance and sleep, and practicing mind-body care through meditation. Dr. Kodama is board-certified in both Obstetrics/Gynecology and Obesity Medicine. She specializes in the use of bioidentical hormones for both men and women and earned her certification in Age Management Medicine through Cenegenics.   For twelve years, Dr. Kodama has provided care in her community in the Twin Cities. Prior to her time in Minnesota, she practiced as a physician in the U.S. Army for 12 years, including overseas in Iraq during Operation Iraqi Freedom in 2004.   Dr. Kodama received a Bachelor of Science in Molecular Biophysics and Biochemistry at Yale University, and an MD from New York University School of Medicine. She completed her residency in Obstetrics and Gynecology at Tripler Army Medical Center in Honolulu, Hawaii. She is an avid reader and enjoys spending time with her husband and two children.

Today’s episode is the thirteenth of several highlight shows where we are taking a look back at our top 20 favorite interviews and conversations of all time. Today’s featured guest is Samuel Achilefu, PhD, the Director of the Optical Radiology Laboratory at the Washington University School of Medicine. Dr. Achilefu is a professor of Radiology, Biomedical Engineering, and Biochemistry and Molecular Biophysics. He performs groundbreaking research in the field of cancer research, including the invention of cancer goggles, which were developed to help surgeons see and remove cancer in patients.

Jeremy Smith is the Governor's chair for molecular biophysics and Director of the UT/ORNL Center for Molecular Biophysics at Oak Ridge National Laboratory. They've been modeling surrounding COVID-19 using ORNL's Super Computer, Summit.

Graduating with a PhD is an unbelievable accomplishment. It is the culmination of many years of sweat, tears, hard work, and dedication. And for many who have finally received their PhD diploma, the next step is to get into a Postdoctoral Fellowship program. The transition can be difficult, so where can postdocs turn to in order for them to transition smoothly from graduate school to their next big adventure? The Postdoc Academy is designed just for that.  Dr. Sarah Chobot Hokanson is Assistant Provost, Professional Development & Postdoctoral Affairs at the Boston University School of Medicine where she provides services and programming for all postdoctoral scholars at Boston University. Previously, Dr. Hokanson was US Deputy Director of Science and Innovation at the British Consulate-General in Boston.  Dr. Hokanson has received an Executive Education Certificate for the Entrepreneurship Development Program from MIT Sloan School of Management. She also completed an NIH Ruth L. Kirschstein Postdoctoral Fellowship at Cornell University in the Department of Chemistry and Chemical Biology. She graduated with a Bachelor of Arts degree in Chemistry from Boston University and has earned her Ph.D. degrees in Biochemistry and Molecular Biophysics from the University of Pennsylvania School of Medicine. What You’ll Hear On This Episode of When Science Speaks [1:04] Mark introduces Dr. Sarah Chobot Hokanson [2:58] The Launch of the Postdoc Academy [3:48] The first course, ‘Succeeding as a Postdoc’, is open for registration now [4:22] Benefits that students receive from joining the Postdoc Academy [7:00] Highlights of the first course [9:59] Plans for upcoming courses Connect with Dr. Sarah Chobot Hokanson Dr. Sarah Chobot Hokanson’s first episode on When Science Speaks Sarah on LinkedIn Sarah on Twitter The transition from graduate student to postdoc Becoming a postdoc is a major challenge and a change. While it’s important to begin the process with focus and attention, but the whole experience isn’t meant to last forever. That’s why it’s important to also give as much value to career planning and on your goals and plans once the Fellowship has been completed. The question is, how do you do this in the most effective way possible? Postdoc Academy was built to address that and the many other questions that come with the decision to pursue Postdoctoral Fellowship. When transitions, new experiences, and planning for the future all happen simultaneously, it can be exhilarating. Postdoctoral candidates are often busy with many activities which is why the course designed by Postdoc Academy is flexible. The goal of the entire course is to provide transferable skills to postdocs in a wide variety of career paths through a comprehensive program. The course takes place over six weeks, with one week modules, but the weekly sections need not be completed until the six weeks have all been duly accomplished since the priority is the schedule and other study commitments of postdoc candidates. The cost of the course is also flexible with paid tracks available that will award certification and credentials.  Succeeding as a postdoc Leveling up from graduate school to a postdoctorate fellowship program is a major change. Not only will your expectations but so too will your routines. So what can you expect when you sign up with Postdoc Academy? What topics will be covered and learnings and benefits can you get from joining their course? Most importantly, how much will it cost to participate in a course? The first course is called “Succeeding as a postdoc”, and is organized into four modules. It is focused on the transition between being a graduate student and career planning. The first module is a general overview and forming a career plan. The next module focuses on how to implement a career plan. Because stress can be a challenge for many postdocs, the third module is about resilience and stress management. The fourth and final module fulfills the Academy’s commitment to diversity and is about working in intercultural environments.  Learn more about Dr. Sarah Chobot Hokanson and Postdoc Academy on this week’s episode of When Science Speaks. Connect With Mark and When Science Speaks http://WhenScienceSpeaks.com https://bayerstrategic.com/ On Twitter: https://twitter.com/BayerStrategic On Facebook: https://www.facebook.com/Bayer-Strategic-Consulting-206102993131329 On YouTube: http://bit.ly/BSConTV On LinkedIn: https://www.linkedin.com/in/markdanielbayer/ On Instagram: https://www.instagram.com/bayerstrategic/ On Medium: https://medium.com/@markbayer17 Subscribe to When Science Speaks on Apple Podcasts or Stitcher

Texas Biomed trainees team up to produce a podcast about their experiences. Biomedical research trainees are an important part of the team of scientists at Texas Biomed. The next generation of innovative thinkers will grow out of those people working in labs all over the country while earning their higher degrees and conducting their post-doctoral work. In this podcast, you will hear from: Colwyn Headley, Ph.D. Candidate in Biomedical Science (Immunology) from Ohio State University. Kizil Yusoof, Masters student in Immunology and Infection at UT Health San Antonio Maritza Quintero, Ph.D. Candidate in Molecular Biophysics and Biochemistry at UT Health San Antonio Amanda Rae Mannino, MLS (ASCP), Ph.D. Candidate in the Cell Biology, Genetics and Molecular Medicine Discipline  

Dr Gail Bradbrook is co-founder of Extinction Rebellion and joins us to talk about women in science and rebelling for our climate future. Recorded 3 October 2019 Photo credit: Kay Michael, Extinction Rebellion

Otras charlas de Codemotion 2019 también en podcast: https://lk.autentia.com/Codemotion-Podcast The project is being coordinated by a group of volunteers with experience in computer vision / natural language processing, Leukemia research, Biochemistry, Molecular Biophysics, Immunology and Bioinformation. The purpose of the project is to share public information related to AML/ALL, as well as open source projects aimed at early dectection with convolutional neural networks, using natural language understanding for AML/ALL chatbots, and R&D for discovering potential candidates for drugs for AML/ALL.

In this episode, we talk to Robert W. Fernandez from Lima, Peru. In this conversation, Robert shares his journey of once being an undocumented immigrant to now becoming a PhD candidate of Molecular Biophysics & Biochemistry at Yale University. He highlights the significant role his mentors have played in helping him navigate his personal and academic growth. As to our question on how he found his mentors, he smiled and said, “by luck.” He suggests seeking a mentor that has a common goal as you. Robert can be reached at rfernandez@gmail.com. If you love this podcast, you can support us with a small, monthly donation. Your contribution will help us to make more episodes. Link to support us: anchor.fm/anuzdipika --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/anuzdipika/support

Dr. Clifford A. Pickover is a researcher, scientist and author. He received his Ph.D from Yale University's Department of Molecular Biophysics and Biochemistry. He has authored more than 50 books. He has also been granted more than 600 U.S patents. His work and his research have been featured on media outlets such as CNN, WIRED and the New York Times. And now The Human Experience

Have you ever been curious about naturopathic medicine? Have you felt overwhelmed by the plethora of conflicting advice on health and nutrition? On this week’s podcast, Cynthia and her guest, Dr. Laura Deville, shed light on all of the above and simplify some very seemingly complicated subjects. Dr. Lauren Deville is board-certified to practice medicine in the State of Arizona. She received her NMD from Southwest College of Naturopathic Medicine in Tempe, AZ, and she holds a BS in Biochemistry and Molecular Biophysics from the University of Arizona with minors in Spanish and Creative Writing. She also loves yoga, piano, and good audiobooks. She writes fiction under a pen name in her spare and she maintains a movie review blog with her cinephile husband.   Is it time to make some changes in your life? Do you want to stop the madness and get on track with your health? Maybe coaching is right for you. I've helped many people gain their health back over the years, and would love to talk with you. Just reach out with the link below to get on my schedule. From time to time I have openings for new clients, and accept them on a first come first serve basis. Book a Discovery Call    

Molecular biophysicist and queer lit slut Joe Osmundson gets into it with Tina on the great debate of our time: saline vs water enemas. You'll be surprised by their, um, artisanal isotonic douche solutions! Discussed: the inner and outer world of the epithelium, why queer sexual health is under-studied, why you should listen to Frank Ocean while giving yourself an enema, why the douche and cuddle is the new Netflix and chill. //Joseph Osmundson is a scientist and writer based in New York City. He has a PhD from The Rockefeller University in Molecular Biophysics. His research has been supported by the American Cancer Society, published in leading biological journals including Cell and PNAS, and he's currently a Clinical Assistant Professor of Biology at NYU. His writing has appeared in The Village Voice, The Los Angeles Review of Books, Gawker, The Kenyon Review, The Rumpus, The Lambda Literary Review, and The Feminist Wire, and elsewhere, too. His book, Capsid: A Love Song won the POZ Award for best HIV writing (fiction/poetry) and was a finalist for a Lambda Literary Award. His second book, INSIDE/OUT is now out from Sibling Rivalry Press (January, 2018). He is represented by Katie Kotchman at Don Congdon Associates. With three other queer writers, he co-hosts a podcast, Food 4 Thot, covering dicks drama, and discourse. He's available for campus visits and readings via the contact form on his site. See acast.com/privacy for privacy and opt-out information.

This week we spoke to Dr. Sarah Hokanson, the Assistant Provost for Professional Development and Postdoctoral Affairs at Boston University about how she navigated we way from research in Biology and Molecular Biophysics to a diverse position in higher education administration. Sarah is responsible for postdoctoral affairs, professional development programming and resources for doctoral students and postdocs across the University, as well as supporting the development of University policies related to postdoctoral scholarship. She also provides resources for faculty mentors and PIs applying for grants related to doctoral and postdoctoral training.

What would you say are the most important aspects of postdoc research? Would the learning environment or the availability of mentors rank high on your list? What about the role of passion and enthusiasm for your field of study? Dr. Sarah Chobot Hokanson joins Mark in this episode of When Science Speaks to highlight the role of enthusiasm and storytelling in postdoc research. Sarah is the Assistant Provost of Professional Development and Postdoctoral Affairs at Boston University. She is responsible for providing services and programming for all postdoc scholars at Boston University, as well as supporting the development of University policies related to postdoc scholarships. Before joining Boston University, Sarah was the US Deputy Director of Science and Innovation at the British Consulate-General, Boston. Dr. Hokanson holds a BA in Chemistry from Boston University and a Ph.D. in Biochemistry and Molecular Biophysics from the University of Pennsylvania School of Medicine. She completed a National Institute of Health (NIH) Ruth L. Kirschstein Postdoctoral Fellowship at Cornell University in the Department of Chemistry and Chemical Biology. What You’ll Hear On This Episode of When Science Speaks [1:08] Mark introduces his guest, Dr. Sarah Chobot Hokanson. [3:50] What sparked Sarah’s interest in science? [7:30] Sarah talks about taking a position working for the British Consulate. [12:00] What is the Postdoc Academy? [15:00] How Sarah and her team create programs that appeal to postdoc researchers. [18:00] Sarah’s advice for postdoc researchers. [20:30] Why enthusiasm for your field is crucial. [22:20] How to connect with the Postdoc Academy. Connect with Sarah Chobot Hokanson Postdocacademy[at]gmail.com Sch1[at]bu.edu Sarah on LinkedIn Sarah on Twitter Resources & People Mentioned National Postdoctoral Association Don’t fake it, pursue what energizes you Have you ever found yourself stuck listening to someone who is dispassionate about their work? The experience tends to be incredibly dull and ultimately a waste of time. While It’s not fair to expect every researcher to come out with the most stunning and captivating presentation, a lack of passion and enthusiasm speaks volumes. What is the solution? Should you fake excitement for something that you don’t care about? Most people are ill-equipped to take a topic they care nothing about and make it sound interesting. Don’t try to fake enthusiasm; your audience will see it coming from a mile away. If you find yourself in a field of study that you don’t care about, make a change as soon as possible. Not only will you benefit from switching to a subject that you care about, but those on the receiving end of your research will also benefit. If you are stuck, consider reaching out to your mentor or peers and utilize the network you’ve built to make a change. Why storytelling is crucial to communicating your research Storytelling is an often neglected aspect of postdoc research. Even the phrase, “Storytelling” seems foreign in a world of facts, figures, and data. What does storytelling have to do with postdoc studies? It all comes down to effectively conveying your findings. If you can’t tell a compelling story with the data you’ve collected, you need to look at it from a different perspective. Your research will only have the desired effect if you present it in a way that connects with your target audience. Are you presenting your findings to your peers? If so, you can get away with a lot of lingo and jargon, but you still need to make a compelling case. Are you presenting to an audience outside your field of study? If that’s the case, you’ve got to find a way to connect your research to something they can understand. You don’t have to abandon your data and figures, you must make them relevant to your audience. This aspect of your research will come more naturally if you are engaged and invested in your subject matter. To hear Dr. Hokanson expand on this topic and much more, make sure to catch her full conversation with Mark on this episode of When Science Speaks. Connect With Mark and When Science Speaks http://WhenScienceSpeaks.com https://bayerstrategic.com/ On Twitter: https://twitter.com/BayerStrategic On Facebook: https://www.facebook.com/Bayer-Strategic-Consulting-206102993131329 On LinkedIn: https://www.linkedin.com/in/markdanielbayer/ On Instagram: https://www.instagram.com/bayerstrategic/ On Medium: https://medium.com/@markbayer17

Dr. Josiah Zayner is a global leader in the BioHacker movement, constantly pushing the boundaries of Science outside traditional environments. We talk about the awesome work he's doing, and how biohacking could save lives. Zayner is the founder of The ODIN, a company that believes the future is going to be dominated by genetic engineering, and that consumer genetic design will be a big part of that. They create kits and tools that allow anyone to make unique and usable organisms at home or in a lab or anywhere. Zayner started BioHacking during his Ph.D. in Molecular Biophysics at the University of Chicago, creating The Chromochord in his apartment, the world’s first musical instrument that uses engineered protein nanotechnology. After his Ph.D., Josiah received a prestigious fellowship to work with NASA's Synthetic Biology program, engineering bacteria to help terraform Mars. Now he is the Founder and CEO of The ODIN. Josiah has a number of Scientific publications and awards for his work in protein and genetic engineering and is also recipient of Art awards for creating Speculative Science works that have been featured in museums across the world, including NY MoMA PS1. His work has been featured in Time, Scientific American, Popular Science, Businessweek, The Verge and NPR, among many others. He enjoys Whiskey and Red Bull, sometimes together. You can find his personal blog at http://josiahzayner.com

Samuel H. Sternberg, PhD, is a protein-RNA biochemist and CRISPR expert. He runs a research laboratory at Columbia University, where he is assistant professor in the Department of Biochemistry and Molecular Biophysics. He is the co-author, along with Jennifer Doudna, of A Crack in Creation, a popular science book about the discovery, development, and applications of CRISPR-Cas9 gene editing technology. For more episodes or information about "The State of The Universe with Brendan Drachler" visit thestateoftheuniverse.com or follow Brendan on Twitter and Instagram @BrendanDrachler. The State of the Universe is an accessible science and social podcast hosted by Astrophysicist Brendan Drachler. Listen to Brendan and other renowned members of the scientific community discuss and explain the cutting edge research occurring across the world today!

(Repeat) The biotech tool CRISPR lets us do more than shuffle genes. Researchers have embedded an animated GIF into a living organism's DNA, proving that the molecule is a great repository for information. This has encouraged speculation that DNA could be used by aliens to send messages.  Meanwhile, nature has seized on this powerful storage system in surprising ways. Scientists have learned that the 98% of our genome – once dismissed as “junk” – contains valuable genetic treasure. Find out what project ENCODE is learning about the “dark genome.” Plus, how viruses became the original stealth coders, inserting their DNA into ancient bacteria and eventually leading to the development of CRISPR technology. Discover the potential of this powerful tool, from curing disease to making pig organs transplant-friendly, and the possible dark side of quick-and-easy gene editing.   Guests: Paul Davies- Director of the Beyond Center for Fundamental Concepts in Science at Arizona State University Yin Shen- Assistant professor, Department of Neurology, Institute for Human Genetics, University of California – San Francisco, member of ENCODE team  Sam Sternberg- Assistant professor, Department of Biochemistry and Molecular Biophysics, Columbia University, and co-author of “A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution”   Hank Greely- Director, Center for Law and the Biosciences; Chair of the Steering Committee of the Center for Biomedical Ethics; and Director, Stanford Program in Neuroscience and Society Learn more about your ad choices. Visit megaphone.fm/adchoices

(Repeat) The biotech tool CRISPR lets us do more than shuffle genes.  Researchers have embedded an animated GIF into a living organism’s DNA, proving that the molecule is a great repository for information.  This has encouraged speculation that DNA could be used by aliens to send messages.  Meanwhile, nature has seized on this powerful storage system in surprising ways.  Scientists have learned that the 98% of our genome – once dismissed as “junk” – contains valuable genetic treasure. Find out what project ENCODE is learning about the “dark genome.” Plus, how viruses became the original stealth coders, inserting their DNA into ancient bacteria and eventually leading to the development of CRISPR technology.  Discover the potential of this powerful tool, from curing disease to making pig organs transplant-friendly, and the possible dark side of quick-and-easy gene editing.   Guests: Paul Davies- Director of the Beyond Center for Fundamental Concepts in Science at Arizona State University Yin Shen- Assistant professor, Department of Neurology, Institute for Human Genetics, University of California – San Francisco, member of ENCODE team  Sam Sternberg- Assistant professor, Department of Biochemistry and Molecular Biophysics, Columbia University, and co-author of “A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution”   Hank Greely- Director, Center for Law and the Biosciences; Chair of the Steering Committee of the Center for Biomedical Ethics; and Director, Stanford Program in Neuroscience and Society

This week, we're presenting stories from scientists who faced unusually difficult paths to science. We all know it's hard work to become a scientist. But for some folks, even getting to that point where you can pursue your science education can seem like an impossible dream. Part 1: When Evelyn Valdez-Ward discovers that she's undocumented, she fears her dreams of becoming a scientist are over.  Part 2: Samuel Achilefu's experiences growing up during the Nigerian Civil War inspire his passion for science. Evelyn Valdez-Ward is an undocumented, Latina, scientist and PhD student at the University of California, Irvine. For her thesis, she studies the impact of California's drought on the ways that plants and their soil microbes (fungi and bacteria in the soil) communicate and interact with one another. In addition to doing research, she's extremely passionate about advocating for undocumented students in STEM. She recently published her story "I'm an undocumented scientist fighting for my Dream" in Science, and was invited to speak at the March for Science rally in DC to advocate for Dreamers in STEM. She has been awarded a UCI's Dynamic Womxn's Award for Outstanding Social Justice Activist, and the Svetlana Bersahdsky Graduate Student Award for her lobbying and advocacy efforts. She plans to continue lobbying and fighting for her undocumented community after graduating, and work in science policy, where she can continue to advocate for both science and minorities in STEM. Originally from Nigeria, Samuel Achilefu is the Michel M. Ter-Pogossian Professor of Radiology at Washington University School of Medicine.  He also holds joint appointments as a Professor in Medicine, Biochemistry & Molecular Biophysics, and Biomedical Engineering and serves as the Chief of the Optical Radiology Laboratory (ORL), Director of the Molecular Imaging Center, Director of the Center for Multiple Myeloma Nanotherapy, and a co-leader of the Oncologic Imaging Program of the Siteman Cancer Center.  His lab harnesses the power of light to develop methods for understanding, diagnosing and treating human diseases and is made up of biologists, chemists, engineers, medical scientists and physicists.  He enjoys biking, playing tennis, and travelling.  Samuel lives with his wife and they have two college-aged children. Learn more about your ad choices. Visit megaphone.fm/adchoices

The heart of all life is DNA. What possibilities open up when one can directly manipulate and alter this fundamental building block…in humans? Josiah Zayner, who holds a PhD in Molecular Biophysics and previously worked with NASA on engineering bacteria to terraform Mars, was drawn to explore the applications genetic engineering could bring to humanity. So much so, in fact, that Josiah performed multiple self-experiments, attempting to genetically engineer the color of his skin and becoming the first known person to directly edit his genes with CRISPR-Cas9. In this discussion, you'll discover: - The nuances of genetic engineering: What it means, how it's done, and why it's currently largely inaccessible - Increasing creativity and divergent thinking by thought expansion by reading atypical books - How the biohacking space can mature and evolve alongside established regulation agencies like the FDA. Check out Josiah's company The ODIN: http://www.the-odin.com/ ---------------------------------------------------------------------------- Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you a free Sprint Mini.

Dr. Nguyen will discuss the Aliso Canyon gas blowout, his educational science videos, Cancer InCytes Magazine, and much more! TUNE in to KUCI 88.9fm Monday at 9:30am pst - stream www.kuci.org David H. Nguyen, Ph.D. Affiliate Scientist Division of Molecular Biophysics and Integrated Bioimaging (MBIB) Lawrence Berkeley National Laboratory Principal Investigator David H. Nguyen, Ph.D. will be discussing the following: What motivated you to get involved in the Aliso Canyon gas blowout? What are your goals regarding the educational science videos that you have been making? Are your videos applicable to people outside of the Aliso Canyon gas blowout? You’re the editor-in-chief if Cancer InCytes Magazine. Tell me about Cancer InCytes. What should the poisoning victims in the San Fernando Valley be doing to protect themselves? How can our listeners help your efforts and the people living near Aliso Canyon? About David H. Nguyen, Ph.D. Professional Activities Editor-in-Chief of Cancer InCytes Magazine, a public health e-magazine that talks about the links between childhood trauma, social justice, environmental toxicology, and disease risk: www.CancerInCytes.org Affiliate Scientist at Lawrence Berkeley National Laboratory. He is part of the Molecular Biophysics and Integrated Bioimaging Division. www.biosciences.lbl.gov/divisions/mbib Principle investigator at Tissue Spatial Geometrics Laboratory: www.tsglab.org Chair of the Environmental & Medical Fallout Task Force about Aliso Canyon Gas Blowout: https://www.cancerincytes.org/task-force-gas-blowout Research Interests Develops mathematical algorithms to measure order and disorder in tumor architecture to better diagnose disease and predict future risk of disease. www.tsg-lab.org Education Studied Molecular & Cell Biology at UC Berkeley for his undergraduate degree. Studied endocrinology and cancer for his PhD at UC Berkeley. Background Grew up in Los Angeles area in a family of Vietnamese immigrants. David H. Nguyen, Ph.D. Tissue Spatial Geometrics Lab (TSG Lab) Lab Website: www.tsg-lab.org Contact Email: DHNguyen@lbl.gov Personal Website: www.d-hh-nguyen.com

“The bottom line is: there are always going to be challenges, but that’s why you are there.” — Dr. Samuel Achilefu, PhD Today’s guest is Samuel Achilefu, PhD, the Director of the Optical Radiology Laboratory at the Washington University School of Medicine. Dr. Achilefu is a professor of Radiology, Biomedical Engineering, and Biochemistry and Molecular Biophysics. He holds the Michel M. Ter-Pogossian Endowed Chair in Radiology, and serves as Vice Chair of Innovation and Entrepreneurship at the Mallinckrodt Institute of Radiology. He performs groundbreaking research in the field of cancer research, including the invention of cancer goggles, which were developed to help surgeons see and remove cancer in patients.

Bryan Doreian is the President and founder of Wysebridge Patent Bar Review, an inventive startup designed to help individuals pass the Patent Bar Exam efficiently. This is achieved by providing online resources and materials in a way that anyone can understand, and the means to quickly and efficiently develop the skills to pass. Bryan Doreian has a background in many areas of research including Chemistry, Chemical Engineering, and a PhD in Cellular and Molecular Biophysics. He has not only developed analytical skills allowing him to process and summarize information and data, but also how to quickly and efficiently find solutions to problems. Bryan Doreian's experience in multiple sectors is diverse, providing him with a unique perspective into the field of patents and intellectual property. He has been involved in drug development, process design and control for a major manufacturer, biomedical academic research, and is working on quantitative reforms for the healthcare industry.

Bryan Doreian is the President and founder of Wysebridge Patent Bar Review, an inventive startup designed to help individuals pass the Patent Bar Exam efficiently. This is achieved by providing online resources and materials in a way that anyone can understand, and the means to quickly and efficiently develop the skills to pass. Bryan Doreian has a background in many areas of research including Chemistry, Chemical Engineering, and a PhD in Cellular and Molecular Biophysics. He has not only developed analytical skills allowing him to process and summarize information and data, but also how to quickly and efficiently find solutions to problems. Bryan Doreian's experience in multiple sectors is diverse, providing him with a unique perspective into the field of patents and intellectual property. He has been involved in drug development, process design and control for a major manufacturer, biomedical academic research, and is working on quantitative reforms for the healthcare industry.

Sam Harris speaks with Jennifer Doudna about the gene-editing technology CRISPR/Cas9. They talk about the biology of gene editing, how specific tissues in the body can be targeted, the ethical implications of changing the human genome, the importance of curiosity-driven science, and other topics. Jennifer A. Doudna is a professor in the Chemistry and the Molecular and Cell Biology Departments at the University of California, Berkeley, investigator with the Howard Hughes Medical Institute, and researcher in the Molecular Biophysics and Integrated Bioimaging Division at the Lawrence Berkeley National Laboratory. She is internationally recognized as a leading expert on RNA-protein biochemistry, CRISPR biology, and genome engineering. She is the author (with Samuel Sternberg) of A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution.

CRISPR technology could change the world. Essentially, CRISPR is a technique that allows scientists to make precision edits to any DNA, whether bacterial or human. The potential for this technology is huge: if scientists have the accuracy to replace just a few faulty genes, it might be possible to cure genetic disorders as serious as cystic fibrosis and Huntington's disease and as common as lactose intolerance and color-blindness. Dr. Sam Sternberg, CRISPR expert and protein-RNA biochemist, joins the Curiosity Podcast to explain the science, ethics, and future of this cutting-edge technology. Samuel H. Sternberg, PhD, will be starting his own research laboratory at Columbia University in early 2018, as an assistant professor in the Department of Biochemistry and Molecular Biophysics. Along with Jennifer Doudna, he is the co-author of A Crack in Creation, a popular science book about the discovery, development, and applications of CRISPR-Cas9 gene editing technology. More from Curiosity: Get $50 off a Full Havenly Design package with promo code CURIOSITY Start your one free month of The Great Courses Plus (Special for Curiosity Podcast listeners) Scientists Trimmed the Fat by Genetically Engineering Leaner Pigs What Is CRISPR, And How Does It Work? Scientists Are Only Just Beginning To Discover What Causes Gray Hair Scientists Turn To This Film To Make People Cry Additional resources discussed: Samuel H. Sternberg, PhD official website "A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution" "Gattaca" (1997 film starring Ethan Hawke and Uma Thurman) 'Three-parent baby' claim raises hopes — and ethical concerns (Nature) Genome-editing revolution: My whirlwind year with CRISPR (Jennifer Doudna's article in Nature) Useful Mutants, Bred With Radiation (New York Times) Sorry Hipsters, That Organic Kale Is a Genetically Modified Food (Smithsonian) Gene Editing Makes Cows Without Horns (Popular Science) Ben Mezrich's Woolly Mammoth Book Being Adapted Into Movie by Fox "Woolly: The True Story of the Quest to Revive One of History's Most Iconic Extinct Creatures" How to Extract DNA from a Strawberry (YouTube) 23andMe direct-to-consumer genetic testing Neutron-Star Collision Reveals Origin of Gold, Astronomers Say (Live Science) Astronomers Strike Gravitational Gold In Colliding Neutron Stars (NPR)To learn more about this topic and many others check out Curiosity.com, download our 5-star iOS or Android app and join the conversation on Facebook and Twitter. Subscribe on iTunes, Stitcher, Google Play Music, and everywhere else podcasts are found so you don't miss an episode! See omnystudio.com/listener for privacy information.

On this episode, Dr. Josiah Zayner joins us all the way from San Francisco. Josiah got his bachelor’s degree in plant biology at Southern Illinois University, his master’s degree in cell and molecular biology at Appalachian State, and then his PhD in Biochemistry and Molecular Biophysics at the University of Chicago. He worked as a research scientist at NASA in the synthetic biology program before leaving to work full-time as a biohacker. He is the founder and CEO of The Odin and has gained a lot of attention for his creative and daring approach to science. We talked about NASA, the future of scientific inquiry, self-experimentation, and so much more!

Kimberley Gibson is a research assistant in Chuck Sindelar's lab in the Department of Molecular Biophysics & Biochemistry. I sat down with Kim to discuss lab cultures, best practices in mentorship, and the differences between the Canadian and American scientific systems.

Ashley Schloss is a 5th year PhD candidate--and soon-to-be PhD!--in Lynne Regan's lab at the Department of Molecular Biophysics and Biochemistry. Anthony Scruse is a 3rd year PhD Candidate in the Department of Chemistry.

Professor Lynne Regan from Yale's Department of Molecular Biophysics and Biochemistry believes in the power of active learning. In this episode she shares what she's learned incorporating active learning exercises into her classes.

Dr. Charles Cockell is a Professor of Astrobiology in the School of Physics and Astronomy at the University of Edinburgh and Director of the UK Centre for Astrobiology. In addition, he is the Founder and Chair of the Earth and Space Foundation and also the Co-Founder, current Board Member, and Past President of the Association of Mars Explorers. Charles has also been elected as an International Fellow of the Explorers Club. He did his undergraduate training in Biochemistry and Molecular Biology at Bristol University and received his PhD in Molecular Biophysics from the University of Oxford. Prior to joining the faculty at the University of Edinburgh, Charles was a National Academy of Sciences Associate with NASA, a visiting Scholar at both Stanford University and the University of Arizona, a Research Scientist with the British Antarctic Survey, and also Professor of Geomicrobiology at Open University. Charles is here with us today to tell us all about his journey through life and science.

Dr. James Pipas is the Herbert W. and Grace boyer Chair in Molecular Biology and Professor of Biological Sciences at the University of Pittsburgh. He received his PhD in Molecular Biophysics from Florida State University and completed his postdoctoral training at Baylor College and the John Hopkins School of Medicine. Jim has been a faculty member in the Department of Biological Sciences at the University of Pittsburgh now for over 30 years. Jim is here with us today to tell us all about his journey through life and science.

Reflections on the current state of the Yale Graduate School of Arts and Sciences by Dean Thomas Pollard, M.D., Sterling Professor of Molecular, Cellular & Developmental Biology, and Professor of Molecular Biophysics and Biochemistry and Cell Biology.

If you experience any technical difficulties with this video or would like to make an accessibility-related request, please send a message to digicomm@uchicago.edu. Erin Adams, Assistant Professor, Biochemistry & Molecular Biophysics, Committee on Immunology, The University of Chicago, and Thomas Rosenbaum, Provost, The University of Chicago, discuss how inter-disciplinary collaboration, cutting edge science research, and important societal problems factor into the creation of the Institute for Molecular Engineering at The University of Chicago.

Thomas Steitz, Sterling Professor of Molecular Biophysics and Biochemistry, was awarded the Nobel Prize in Chemistry for showing how ribosomes function, work that has important implications for antibiotics.

Dr. Thomas Steitz, Sterling Professor of Molecular Biophysics and Biochemistry and Howard Hughes Medical Institute Investigator, headed the team that mapped the ribosome's structure.

Seth Darst is a professor of Molecular Biophysics at the Rockefeller University in New York city, where his research centers on RNA polymerase, the enzyme at the heart of a cell’s ability to make protein from a set of DNA instructions. In this interview, I talk with Dr. Darst about how he got his start in research, whether computers will eventually be able to predict complex protein structures, and why eager young scientists shouldn’t miss their chance at postdoctoral training.

Joan Steitz, Sterling Professor of Molecular Biophysics & Biochemistry and HHMI Investigator and her Postdoctoral Fellow Shobha Vasudevan discuss their recent findings on microRNAs acting as activators as well as repressors of gene activity.

Scott Strobel, chair and professor of Molecular Biophysics and Biochemistry and Howard Hughes Medical Institute professor, believes the way science is taught deadens enthusiasm rather than kindling curiosity.

Dr. Richard Lifton, chair of the Department of Genetics, Sterling Professor of Genetics, Medicine and Molecular Biophysics and Biochemistry, Investigator Howard Hughes Medical Institute, talks about how common human diseases account for the vast majority of deaths in our society and are known to have underlying inherited components.