Podcasts about ihmc

Our guest today is Dr. Ken Forbus, the Walter P. Murphy Professor of Computer Science and a Professor of Education at Northwestern University. Joining Dr. Ken Ford to co-host today's interview is Dr. James Allen, who was IHMC's associate director until he retired a few years ago. James is a founding fellow of the American Association for Artificial Intelligence and a perfect fit for today's discussion with Dr. Forbus, who, like James, is an AI pioneer.  Back in 2022, James was named a fellow by the Association for Computational Linguistics, an organization that studies computational language processing, another field he helped pioneer. Dr. Forbus also is a Fellow of the Association for the Advancement of Artificial Intelligence and was the inaugural winner of the Herbet A. Simon Prize for Advances in Cognitive Systems. He is well-known for his development of the Structure Mapping Engine. In artificial intelligence and cognitive science, the Structure Mapping Engine is a computer simulation of analogy and similarity comparisons that helped pave the way for computers to reason more like humans. Show Notes: [00:03:07] Ken opens the interview with Dr. Forbus by asking if it is true that he had an unusual hobby for a nerdy kid growing up. [00:04:18] James mentions that Dr. Forbus' family moved often when he was younger and asks how that affected him. [00:05:18] Ken mentions that when Dr. Forbus was in high school, he filled his free time reading about psychology and cognition before eventually coming across some articles on AI. Ken asks Dr. Forbus to talk about this experience and what happened next. [00:07:49] James asks Dr. Forbus if he remembers the first computer he owned. [00:09:17] Ken asks Dr. Forbus if there was anything, other than its reputation, that led him to attend MIT. [00:10:09] James mentions that for the past few decades, Dr. Forbus has been working on developing “human like” AI systems. While much of AI research and development has been focused on meeting the standard of the Turing test, James asks Dr. Forbus why he is not a fan of the Turing test. [00:12:24] Ken mentions that Dr. Forbus received his Ph.D. from MIT in 1984, the same year that Apple released the first Macintosh, which was rolled out with a famous Super Bowl ad. This computer was the first successful mouse driven personal computer with a graphical interface. Ken asks Dr. Forbus what he remembers about that ad, and what his reaction to it was at the time. [00:13:22] James mentions that 1984 was also the year that Dr. Forbus made his first splash in the AI world with his paper on qualitative process theory. James goes on to explain that at the time, qualitative reasoning regarding quantities was a major problem for AI. In his paper, Dr. Forbus proposed qualitative process theory as a representational framework for common sense physical reasoning, arguing that understanding common sense physical reasoning first required understanding of processes and their effects and limits. James asks Dr. Forbus to give an overview of this paper and its significance. [00:18:10] Ken asks Dr. Forbus how it was that he ended up marrying one of his collaborators on the Structure Mapping Engine project, Dedre Gentner. [00:19:14] James explains that Dedre's Structure Mapping Theory explains how people understand and reason about relationships between different situations, which is central to human cognition. James asks Dr. Forbus how Dedre's theory was foundational for the Structure Mapping Engine (SME). [00:25:19] Ken mentions how SME has gone through a number of changes and improvements over the years, as documented in Dr. Forbus' 2016 paper “Extending SME to handle large scale cognitive modeling.” Ken asks, as a cognitive model, what evidence Dr. Forbus has used to argue for the psychological and cognitive plausibility of SME. [00:30:00] Ken explains that many AI systems rely on deep learning,

Today we have planetary scientist Dr. Pascal Lee and STEM-Talk host Dr. Ken Ford in a wide-ranging conversation about NASA's ambitions to return humans to the Moon as a stepping stone to sending astronauts to Mars. Pascal is making his third appearance on STEM-Talk. Much of his research focuses on asteroids, impact craters, and the future human exploration of Mars. Pascal and Ken have a lively discussion about the growing momentum for space exploration. Pascal is a researcher at the SETI Institute, a not-for-profit NASA program focused on searching for extraterrestrial intelligence in an effort to understand and explain the origin and nature of life in the universe. He also is the co-founder and chairman of the Mars Institute, and director of the Haughton-Mars Project at NASA Ames Research Center. Last year, Pascal received significant news coverage for his discovery of a giant volcano along with a possible sheet of buried glacier ice in the eastern part of Mars' Tharsis volcanic province. This was the first geological find of this magnitude since the other major volcanos on Mars were discovered back in the 1970s. Show notes: [00:03:06] Ken welcomes Pascal back to STEM-Talk and starts our interview by mentioning the developments in space exploration over the past few years, including civilian space missions, NASA's Artemis program which aims to send humans back to the moon, and commitments to a manned mission to Mars. Given Pascal's career in advancement of space exploration, Ken asks if Pascal is excited by these recent developments. [00:04:43] Ken explains that for a couple of decades Pascal has spent his summers visiting Devon Island in the Canadian arctic archipelago, which is the largest uninhabited land on Earth. When Pascal was last on STEM-Talk, his annual trip to Devon Island was cancelled due to COVID-19. Devon Island has unique geological characteristics that are in some ways similar to those on Mars. Since 2001, Devon Isalnd has been the home of the Haughton Mars Project (HMP). Ken asks Pascal to talk about the advances in this project since his last appearance on STEM-Talk. [00:07:59] Ken mentions that while much conversation has been centered on a human trip to Mars, a mission to return humans to the Moon and establish a permanent base is a more immediately feasible goal in the short term. Ken asks Pascal to talk about the importance and significance of such a mission. [00:12:06] On the topic of a Moon base, Ken explains that NASA's Artemis project aims to send humans to the south pole of the Moon. Pascal has written a paper on that topic titled “An Off-Polar Site Option for the NASA Artemis Space Camp.” Ken asks Pascal what he sees as the primary weakness in the south pole location. [00:20:25] Ken agrees with Pascal's perspective on sending humans to the lunar south pole, and the two discuss the problems with focusing human space exploration on romantic ideas such as “living off the land.” [00:22:24] Ken follows up on the previous questions by mentioning that in Pascal's aforementioned paper, he suggests setting up a lunar base at the floor of the Clavius crater. Ken asks Pascal to talk about Clavius and why it is a potentially good permanent location for a moon base. [00:27:56] Ken asks Pascal how confident he and the community at large is in the Sophia finding of water. [00:29:00] Ken notes that contemporary interest in human space exploration appears tied to current geopolitical issues, much like the first space race between the US and USSR. Today, interest in space travel is closely linked with relations between the US and China. Ken asks Pascal to discuss this and how he believes the US should view this current situation. [00:35:43] Ken asks Pascal what he knows about the China's current plans for a lunar mission. [00:34:36] Ken talks about a meeting at IHMC that addressed power-beaming to the lunar surface. [00:39:01] Ken notes that there is a lot of talk the...

Today we have JP Errico, a scientist and inventor whose work focuses on neuroimmunology and the many ways it impacts cellular metabolism, inflammation, mental health and how we age. He recently joined IHMC as a Senior Research Scientist. JP is particularly known for his research on vagus-nerve stimulation and is the author of the book, The Vagus-Immune Connection: Harness Your Vagus Nerve to Manage Stress, Prevent Immune Dysregulation, and Avoid Chronic Disease. He also is the co-host of the podcast, The Health Upgrade. JP has more than 250 patents and is the founder of ElectroCore, a company that specializes in neuromodulation and noninvasive vagus-nerve stimulation. He has an undergraduate degree in aeronautical engineering from the Massachusetts Institute of Technology and worked at Lincoln Laboratories. JP also holds graduate degrees in both law and mechanical/materials engineering from Duke University. Show notes: [00:03:08] Tim opens our interview mentioning that as a child JP was focused on both sports and academics. [00:04:50] Tim talks about how hard it is to find quality math and science education today similar to what JP experienced at his high school. [00:05:16] Tim asks JP what it was that led him to pursue an undergraduate degree at MIT. [00:05:53] Tim asks if it was always JP's plan to go into aeronautical engineering. [00:07:22] Tim mentions that as a kid, JP would scour bookstores and libraries for textbooks on physics and quantum mechanics and asks JP if there were any books that particularly inspired him. [00:10:12] Ken mentions that after MIT, JP went to Duke University where he pursued mechanical engineering and also went to law school. Given this workload, Ken asks if JP ever had any free time while studying at Duke. [00:13:26] Tim mentions that while JP was in law school, he got a job at a patent firm. After obtaining his law degree, JP's uncle called and offered JP an opportunity. [00:17:42] Tim explains that JP's career has focused on neuroimmunology, or the study of how the nervous system and immune system interact. Neuroimmunology affects a wide range of health factors including inflammation, mental health and aging. Tim also explains that JP has recently authored a book on neuroimmunology titled “The Vagus Immune Connection: Harness Your Vagus Nerve to Manage Stress, Prevent Immune Dysregulation and Avoid Chronic Disease.” Tim asks JP to touch on the key features of neuroimmunology that people should be aware of. [00:21:59] Tim asks JP to touch on the epigenetic factors regarding neuroimmunology. [00:25:01] Since JP brought up Dr. Kevin Tracey's work, Ken mentions that Kevin was recently interviewed on STEM-Talk episode 172 and encourages listeners to listen to that episode for more context on the vagus nerve and neuroimmunology. [00:25:48] JP talks about how he stumbled upon the idea of how stimulating a nerve may have the same clinical benefit that sometimes occurs as a result of cutting a nerve. [00:28:16] Tim talks about the unintended consequences he observed as surgeon when he cut a patient's vagus nerve. [00:30:50] Ken mentions that another area where JP has had impact with respect to stimulating the vagus nerve is the treatment of asthma and asks JP to talk about his findings in this area. [00:40:10] Tim notes that after JP knew that non-invasive approaches to vagus-nerve stimulation were possible, he went on to optimize a delivery device. These efforts resulted in a device called gamaCore. Tim asks JP to talk about this device and how it works. [00:43:27] Tim asks JP to talk about what it feels like for patients to have their vagus nerve stimulated. [00:44:50] Ken asks if JP thinks that his and others' work in vagus-nerve stimulation inspired the development of similar devices for orthopedic pain, where the device is implanted near the nerve on the knee or other area experiencing pain.

Today we have Dr. Karl Herrup, a neurobiologist known for his investigations into the roles that DNA damage and noncoding genetic variants have in Alzheimer's disease. Joining Ken today to interview Karl is Dr. Tommy Wood, a visiting scientist here at IHMC.  Tommy also is an associate professor of pediatrics and neuroscience at the University of Washington, where he focuses on brain health across lifespan. He has been our guest several times on STEM-Talk and we will have links to those interviews in our show notes for today's episode. After more than a century of research, the underlying cause of Alzheimer's remains a mystery. For the past few decades, the leading theory has been the amyloid cascade hypothesis, which proposes that abnormal amyloid plaques in the brain are the central cause of the disease. Today we talk to Karl about his lab and research as well as his view that the amyloid cascade hypothesis is not only flawed,  but also could be holding back research for a cure of Alzheimer's. A professor of neurobiology and an investigator in the Alzheimer's Disease Research Center at the University of Pittsburgh School of Medicine, Herrup is the author of How Not to Study a Disease: The Story of Alzheimer's. Show notes: [00:03:50] Tommy asks Karl what he was like as a kid to open the interview. [00:04:36] Tommy asks Karl about his educational environment growing up. [00:05:10] Ken mentions that Karl went to Brandies University originally with the intent of becoming a physician and asks Karl what happened to change his mind. [00:06:14] Ken asks Karl if it is true that his father was disappointed with Karl's decision to abandon medical school in favor of genetics. [00:07:02] Tommy mentions that Karl began researching genetics in the late 1960s when researchers were just beginning to unravel the secrets of DNA. Tommy asks Karl to discuss why this was such an exciting time to study genetics. [00:08:38] Tommy asks Karl what prompted him to pursue a PhD in neuroscience. [00:11:34] Continuing on the theme of happy accidents, Ken asks if it was also an accident that led to Karl moving to Switzerland for a second post-doc. [00:12:36] Ken asks Karl to expound on his experience taking an overseas post-doc, which was not a common practice in the 1970s. [00:14:11] Ken mentions that Karl has seemed to benefit in his life from the combination of preparation and the willingness to explore opportunities that present themselves. [00:15:00] Tommy mentions that when Karl arrived back in the US from Switzerland, he accepted a faculty position at Yale and asks him to discuss this experience. [00:17:06] Tommy mentions that after Yale, Karl had several faculty appointments, including a seven-year stint in Hong Kong, and asks Karl to talk about that experience. [00:21:36] Tommy asks Karl why, in 2019, he moved back to his hometown to become a professor of neurobiology at the University of Pittsburgh and co-investigator at the university's Alzheimer's research center. [00:24:45] Ken asks Karl to talk about his lab at the University of Pittsburgh, which focuses on the biology of neurodegeneration. [00:26:32] Ken asks Karl if there was anything specific that caused him to shift his focus at this stage in his career so heavily towards Alzheimer's research. [00:28:21] Tommy comments on Karl's hypothesis of the aging brain, noting that it would make sense for the same processes involved in the developing brain to relate to what we see in the aging brain, as these processes are continuous throughout the lifespan. [00:29:54] Tommy pivots to talk about Karl's book, entitled “How Not to Study a Disease: The Story of Alzheimer's” for which Karl interviewed a number of experts and colleagues, asking each one to define Alzheimer's disease in their own words. [00:30:51] Tommy reiterates the point that we still do not have a universally accepted definition of Alzheimer's disease and asks Karl wh...

durée : 00:37:58 - Questions du soir : le débat - par : Quentin Lafay, Stéphanie Villeneuve - En 2017 et en 2022, le centrisme gagnait l'élection présidentielle. En 2022, Emmanuel Macron qualifiait son projet politique d'"extrême centre". Comment le centrisme, associé au compromis et à la modération, peut-il être extrême ? Peut-on parler du macronisme comme d'un "extrême centre" ? - réalisation : François Richer - invités : Fabienne Keller Eurodéputée Renew; Pierre Serna Professeur d'histoire de la Révolution française à l'université Paris 1 Panthéon-Sorbonne, membre de l'Institut d'histoire moderne et contemporaine (IHMC)

durée : 00:37:58 - Questions du soir : le débat - par : Quentin Lafay, Stéphanie Villeneuve - En 2017 et en 2022, le centrisme gagnait l'élection présidentielle. En 2022, Emmanuel Macron qualifiait son projet politique d'"extrême centre". Comment le centrisme, associé au compromis et à la modération, peut-il être extrême ? Peut-on parler du macronisme comme d'un "extrême centre" ? - réalisation : François Richer - invités : Fabienne Keller Eurodéputée Renew; Pierre Serna Professeur d'histoire de la Révolution française à l'université Paris 1 Panthéon-Sorbonne, membre de l'Institut d'histoire moderne et contemporaine (IHMC)

Today we have Dr. Hans Van Dongen, director of the Sleep and Performance Research Center at Washington State University in Spokane. Dr. Kevin Gluck, a senior research scientist at IHMC, joins Dr. Ken Ford to interview Hans about his studies on inter-individual differences in vulnerability to fatigue as well as the cumulative cognitive deficits that follow chronic sleep restriction. Hans is known for his mathematical modeling of fatigue's effects on performance. At the Sleep and Performance Research Center, Hans and his colleagues investigate how sleep loss and circadian misalignment impact brain function, cognition and behavior. Show notes: [00:02:50] Kevin opens the interview by asking Hans about his childhood growing up in The Netherlands. [00:03:23] Ken asks Hans what he was like as a kid. [00:03:50] Kevin mentions Hans's father was a math and science teacher and wonders if that influenced Hans' interest in science. [00:04:48] Hans talks about attending Leiden University and explains why he majored in astrophysics. [00:06:09] Hans shares how working in a psychophysiology lab put him on a path to specialize in sleep research. [00:08:00] Hans talks about how he was part of a study that proved the morning-evening chronotype was a biological trait, rather than a psychological one. [00:09:55] Ken asks Hans what led him to take a post-doc position at the University of Pennsylvania. [00:11:22] Hans explains what led him to move from the University of Pennsylvania to Washington State University. [00:13:36] Ken mentions that The Sleep and Performance Research Center, where Hans serves as the director, is a coalition of basic and applied research laboratories that aim to understand the neurobiology of sleep and sleep loss. Ken goes on to mention that Hans and his colleagues investigate sleep and biological rhythms, and their impact on health and performance. Kevin asks Hans to give an overview of what sleep loss is and the effect it has on our metabolism, immune system, and cognitive performance. [00:15:57] Kevin mentions Hans' recent paper which investigated how circadian misalignment due to night shift work has been associated with an elevated risk of chronic disease. The paper demonstrated that just a few days of being on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism, and inflammation. Kevin asks Hans to talk more about the findings. [00:21:18] Ken asks how long it takes for a person's circadian rhythm to normalize after ceasing to work night shifts. [00:22:13] Kevin brings up Hans' paper on the continually operating neurobiological mechanisms of homeostatic and circadian processes and their effects on neurobehavioral performance. Before asking about the paper itself, Kevin asks Hans to give an overview of the homeostatic process and its relationship to the circadian process. [00:24:14] Ken notes that the bio-behavioral function and evolutionary advantage of the circadian process is widely recognized, but that the neurobiology of the homeostatic process and its effects on performance are still poorly understood. In a 2011 paper, Hans attempted to shed light on the underlying mechanisms of the homeostatic process to provide an explanation for why the buildup of homeostatic pressure resulting from sleep loss leads to instability in vigilant attention. To explore this, Hans first explored the time-on-task effect. Ken asks Hans to explain the time-on-task effect and its role in cognitive performance. [00:27:06] Kevin brings up the “local sleep hypothesis,” which attempts to explain the time-on-task effect. According to the local sleep hypothesis, groups of neurons involved in performing a task will “fall asleep” as a homeostatic consequence of sustained use, which leads to an interruption in information processing, leading to impaired performance. Kevin asks Hans what empirical and scientific evidence exists for the hypothesis...

Dr. Marcas Bamman has received a $7.7 million award from the National Institutes of Health (NIH) for a clinical trial aimed to determine how people age 60 and older attain the health benefits of exercise. 

Science Saturdays are back and ready to turn on new scientific minds this school year.  These 90-minute educational enrichment sessions are a cornerstone piece of community outreach at Florida Institute for Human and Machine Cognition (IHMC). Topics in 2024 will include 3D printing, bottle rockets, secret codes, and more. Shannon Nickinson has the details.

Erica Grancagnolo discusses the importance of IHMC to the city's revitalization and job training.

Rick talks with Sena Maddison, Marcas Bamman, Clark Merritt, Paul Epstein, Daniel Souers, Reggie Dogan, Gwen Bryan, Andrew Martin, DeeDee Davis, Jeff Phillips., Robert Goodspeed, and Erica Grancagnolo.

Today Dr. David LeMay steps in to co-host with Dr. Ken Ford for our interview with Dr. Charles Serhan. Charles is a Harvard professor best known for his discovery of specialized pro-resolving mediators. SPMs are molecules that can activate the natural resolution of inflammation and help people avoid anti-inflammatory drugs. The discovery of SPMs spurred a paradigm shift in our understanding of inflammation and human disease. Charles is the Simon Gelman Professor of Anesthesia at Harvard Medical School and the director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women's Hospital. He also is a co-director of the Brigham Research Institute. David, who was our guest on Episode 69 of STEM-Talk, is a sports medicine and rehabilitation physician with a Pensacola, Florida practice that focuses on lifestyle and performance medicine. He also is a visiting research scientist here at IHMC. Show notes [00:03:33] David opens the interview mentioning that Charles grew up in New York City with a passion for music. David explains that Charles learned to play the vibraphone in junior high and played professionally for a year before going to college. David asks Charles why he decided to pursue science instead of music. [00:04:22] Ken asks Charles what kind of vibraphone he plays. [00:06:02] Ken asks, aside from the desire to help people, if there was something particular about studying science that Charles really enjoyed. [00:06:45] David asks about Charles' experience at the State University of New York at Stonybrook studying biochemistry and immunohistochemistry. [00:07:16] David asks if there was any carry over of skills for Charles from his career in music to his career in science. [00:08:16] Ken mentions that after Charles earned his bachelor's degree, one of his professors persuaded him to go to New York University for a master's and Ph.D. Ken also mentions that at the time Charles worked in the lab of Gerald Wiseman at Woods Hole Marine Biological Laboratory and asks about that experience. [00:12:37] David asks if this experience led Charles to a focus on neutrophil membrane remodeling for his Ph.D. [00:13:59] David asks Charles if it was at the Karolinska Institute where he met his future wife. [00:14:38] Ken asks Charles about one of his mentors, Michael Heidelberg, who gave Charles advice about how to be a good scientist. [00:17:13] David explains that in the 1990's Charles discovered Specialized Pro-Resolution Mediators and has since pioneered a new field on the utility of SPMs for a variety of inflammatory diseases. [00:25:01] Ken backs up to ask Charles what drew him to study inflammation in the first place and how that led him to do more research on the subject than any other scientist. [00:26:26] David asks Charles to touch on some different types of inflammation that the body experiences. [00:35:12] Ken asks Charles about how a trip to Asia during which he developed a hole in his intestines, resulted in first-hand experience on the importance of controlling inflammation. [00:41:00] David asks if Charles was taking any non-steroidal anti-inflammatory medications when he developed peritonitis. [00:41:53] David asks Charles to explain what non-steroidal anti-inflammatory medications do to the healing process. [00:45:35] David brings up a recent discovery in animal models that as animals age, their ability to produce resolution mediators declines, possibly contributing to the loss of muscle mass with age. [00:48:09] Ken asks Charles to talk about the explosion of research into the potential therapeutic applications of SPMs in the treatment of a variety of chronic diseases known to be driven in part by chronic inflammation. [00:51:06] David asks Charles to explain the differences between resolvins, protectins, and maresins, as well as what role each plays in the healing process. [00:56:04] Ken mentions a review article that Charl...

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comThis week on the podcast Mikki speaks to Professor Ken Ford, co-founder and director of the Institute of Human and Machine Cognition. They discuss AI, ketogenic diets, why you can't trust nutrition science and much more.Kenneth Ford is Founder and Chief Executive Officer of the Florida Institute for Human & Machine Cognition (IHMC) — a not-for-profit research institute located in Pensacola, Florida. IHMC has grown into one of the nation's premier research organizations with world-class scientists and engineers investigating a broad range of topics related to building technological systems aimed at amplifying and extending human cognition, perception, locomotion and resilience.Ken is the author of hundreds of scientific papers and six books. He received his Ph.D. in Computer Science from Tulane University. He is a Fellow of the Association for the Advancement of Artificial Intelligence, a charter Fellow of the National Academy of Inventors, and a member of the Association for Computing Machinery, the IEEE Computer Society, and the National Association of Scholars.In February of 2012, Dr. Ford was named to the Defense Science Board (DSB) and in 2013, he became a member of the Advanced Technology Board (ATB) which supports the Office of the Director of National Intelligence (ODNI). In 2018, Dr. Ford was appointed to the National Security Commission on Artificial Intelligence.In 2020, Florida Trend Magazine named Ford one of its Living Legends, a list of all-time influential Florida leaders in business, medicine, academia, entertainment, politics, and sport.He also hosts a popular podcast about science called Stem-talk: https://www.ihmc.us/stemtalk/ Ken Ford: https://www.ihmc.us/groups/kford/ Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

Today's episode of STEM-Talk features Dr. Sten Stray-Gundersen, a post-doctoral research associate at the University of South Carolina who is also an adjunct instructor at the university's Arnold School of Public Health. Cohosts Dr. Ken Ford, IHMC's founder and CEO, and Dr. Marcas Bamman, a Senior Research Scientist at IHMC, talk to Sten about his work on blood-flow restriction training and cardiovascular exercise physiology. Prior to his position at South Carolina, Sten was a teaching assistant at the University of Texas where he earned his Ph.D. Sten's father, Jim Stray-Gundersen, was our guest on episode 34 of STEM-Talk in 2017. Jim, who passed away last year, helped pioneer blood-flow restriction training in the United States. In today's interview, we cover the documented benefits of blood-flow restriction and how it not only increases muscle strength, but also improves endurance and reduces the risk of injury. Sten also talks about his research into hypoxia and endothelial function. Show notes: [00:03:02] Sten begins the interview talking about the different places where he grew up. [00:03:32] Marcas asks if it's true that Sten's high school soccer team won three straight state titles. [00:04:06] Marcas mentions that Sten's younger brother was also a good soccer player in high school, and was on the same team as Sten when they won their third state championship. Sten goes on to talk to talk about playing sports with his siblings. [00:04:43] Ken mentions that Sten was a nationally ranked speed skater and cross-country skier. Ken asks Sten about other sports he excelled at. [00:05:45] Marcas asks how Sten's parents influenced his success in athletics. [00:06:41] Ken takes time to offer his condolences for the passing of Sten's father, Jim Stray-Gundersen, who was interviewed on episode 34 of STEM-Talk. The 2017 interview, which focused on blood-flow-restriction training, remains a popular STEM-Talk episode to this day. [00:08:21] Marcas asks Sten about trying blood-flow restriction (BFR) for the first time with his father. [00:09:37] Marcas asks Sten what led him to become interested in pursuing a career in science. [00:10:27] Ken mentions that Sten went to Dartmouth for his undergrad on a soccer scholarship. After graduating, Sten attempted to play in the USL. and Ken asks how that worked out. [00:11:57] Marcas mentions that as Sten's injuries from soccer piled up, he began to consider going back to school and pursuing research. Marcas asks what went into that decision-making process. [00:13:38] Marcas mentions that during Sten's time in Austin, he worked for a group called ROI Performance, which is an evidence-based physical therapy center that focuses on athletic rehab and performance. Marcas asks Sten to talk about his time there as a BFR specialist. [00:15:23] Marcas takes a moment to explain that BFR training involves restricting the blood flow to specific muscle groups, using specialized cuffs or bands. Marcas asks Sten to explain how BFR allows people to train with lighter weights while still reaping many of the benefits associated with heavier resistance training. [00:16:20] Ken mentions that BFR has largely been associated with resistance training, but it is now being looked at in the context of endurance sports. Ken asks Sten to discuss how different protocols of BFR can be implemented to yield different effects in the contexts of resistance training and aerobic training. [00:19:10] Ken notes that much of the Western research on BFR has now incorporated the arterial occlusion pressure approach, so much so, that it is often promoted as the only safe and effective approach to BFR. Ken goes on to say that this is not how BFR was originally conceived. Ken explains that there are a variety of different approaches to BFR, each with tradeoffs, and asks Sten to discuss these issues in detail. [00:21:22] Ken mentions that clarity is lacking in much of the BFR ...

Today's interview is with Dr. Josh Hagen, the director of the Human Performance Collaborative at Ohio State University and an Associate Research Professor in the university's Department of Integrated Systems Engineering. Joining co-host Ken Ford for this episode is IHMC's Chief Strategic Partnership Officer Morley Stone who has a long history with Josh has and been instrumental in his career. Today we talk with Josh about his work at the Human Performance Collaborate, which brings together multi-disciplinary teams of researchers, sports scientists, data scientists, and practitioners with the goal of optimizing human performance in Ohio State athletes. Within the human performance research area, Josh leads two areas: Sport and Tactical Performance Science and Recovery Science. At Ohio State, Josh works with other performance-science researchers to evaluate the physical traits and capabilities of athletes. Josh and his colleagues then collaborate with coaches and athletic trainers to make adjustments in the weight room, on the field, and during recovery after training or competitions. In addition to his work at Ohio State, Josh also is working on federally funded projects in human performance with Special Operations Command, The Air Force Research Laboratory, the Office of Naval Research and several private foundations. Josh joined IHMC in 2022 in a collaborate role as a Visiting Senior Research Scientist. Josh is a graduate of the University of Cincinnati where he studied and earned a Ph.D. in materials science and engineering. He spent 11 years at the Air Force Research Laboratory, which is where Morley and Josh first worked together. After his stint at the Air Force Research Laboratory, Josh headed for West Virginia University as the director of the Human Performance Innovation Center at the Rockefeller Neuroscience Institute before moving to the Ohio State University. Show notes: [00:03:39] Morley starts the interview asking Josh if he played a lot of sports as a kid. [00:03:54] Morley asks if it is true that in addition to being a bit of a jock, Josh was also a nerd growing up. [00:04:34] Josh talks about the high school chemistry teacher who got him excited about science. [00:06:05] Morley asks how Josh ended up at the University of Cincinnati. [00:07:06] Morley mentions that after Josh earned his bachelor's degree in chemical engineering, he worked for a private company before deciding he did not want to spend his career in chemical engineering. Morley asks about the advice that one of his professors gave Josh at the time. [00:09:03] Ken mentions that it was at the Materials Directorate at the Air Force Research Lab, where Josh first met Morley. Ken asks Morley what he remembers about the young Josh. [00:11:19] Ken turns the question to Josh and asks him about his first impressions of Morley. [00:12:12] Ken mentions that after Josh completed his graduate work, he again went to work in the private sector, and again found it unfulfilling. Josh talks about calling Morley to see if he had a job opening. [00:13:51] Morley mentions that in 2018, Josh left the Air Force and went to work at West Virginia University, where he became the director of the Human Performance Innovation Center at the Rockefeller Neuroscience Institute. Morley asks Josh how that job came about and what sort of work went on in that lab. [00:15:46] Ken mentions that after Josh's time at West Virginia, Morley offered Josh a job at Ohio State University, where Morley was, at the time, the senior vice president for research at Ohio State. Ken asks what this time was like for Josh. [00:17:17] Morley mentions that in Josh's role as the director of the Human Performance Collaborative, he works with a multidisciplinary team, and largely worked with two populations, sports athletes and the military. Morley asks Josh to give a sense of how Josh's lab works with both groups.

Dr. Ken Ford is CEO & founder of the IHMC research institute. He also hosts a popular podcast about science called Stem-talk. Today he shares his expertise and personal experience about the ketogenic diet, and addresses other questions related to nutrition, muscle building, healthy aging, fasting, the state of research, and more.YouTube version:  https://youtu.be/BvBkp7NPZpA   Does Fasting Burn Muscle? (blog post):  https://fastingwell.com/fasting-muscle-loss/   Full show notes and resources:  https://fastingwell.com/episode51/   TIMESTAMPS:  Intro to Dr. Ken Ford & Stem-talk (5:28) // What is a ketogenic diet? (12:36) // When did Ken start keto? (15:39) // How has keto changed? (19:38) // Getting enough protein on keto or fasting (25:00) // Top health benefits of keto (32:41) // A “cyclic” ketogenic diet (41:39) // What constitutes a "well-formulated" ketogenic diet? (45:27) // Making keto sustainable (51:07) // Keto & cholesterol / heart disease (57:05) // Nutrition research reporting (1:05:54) // Erythritol & heart disease news reports (1:10:08) // Exogenous ketone supplements (1:15:31) // Ken thoughts about intermittent fasting (1:21:43) // Risks & benefits of extended fasting (1:25:08) // Prioritizing protein for healthy aging (1:32:40) // Stem-talk podcast (1:41:28) 

Today we have our good friend and colleague Dr. Dominic D'Agostino returning for his third appearance on STEM-Talk. Dom, as most of our longtime listeners know, is well-known for his research into the ketogenic diet and the physiological benefits of nutritional ketosis. Since our last conversation with Dom in 2019, a tremendous body of research has been added to the literature about the therapeutic potential of ketosis. The high-fat, low-carb ketogenic diet has been linked to advances in the treatment of Alzheimer's, cancer, migraines, type-2 diabetes, psoriasis, sleep apnea, psychiatric disorders, traumatic brain injuries as well as a host of other diseases and disorders, which we cover in today's interview. In episode 14 of STEM-Talk, we talked to Dom about his development and testing of metabolic therapies involving the ketogenic diet for a wide range of diseases and conditions. In episode 87, Dom returned to reflect on his 10 years of research focused on the high-fat/low-carbohydrate diet. In today's interview, we talk to Dom about this latest work as well as his extensive research on hyperbaric oxygen. Dom is a tenured Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani. He specializes in neuroscience, molecular pharmacology, nutrition, and physiology. Dom also is our colleague and a research scientist here at the IHMC. Show notes  [00:02:50] Dawn opens the interview mentioning Dom's recent IHMC Evening Lecture, in which he mentions the film “First Do No Harm” starring Meryl Streep. The film is based on the true story of a four-year-old boy diagnosed with severe epilepsy, whose extreme seizures continued despite extensive medical treatments. The boy's mother reached to Dr. John Freeman, a physician who had successfully treated patients with a ketogenic diet. Dawn asks Dom to give some context about this fictional film based on a true story. [00:05:05] Dawn asks Dom to discuss the many evidence-based applications of the ketogenic diet that he highlighted in his IHMC evening lecture. [00:07:11] Ken asks Dom about another story involving Russell Winwood, a man with severe chronic obstructive pulmonary disease, also known as COPD. Russell reached out to Dom with respect to treating his COPD with a ketogenic diet. [00:11:21] Ken asks if Russell only engaged in the ketogenic diet or if also used exogenous ketones. [00:12:10] Ken mentions that the ketogenic diet has the broad potential to be an anti-inflammatory diet. Ken goes on to mention that COPD is an inflammatory disease. As Dom's case report suggested, Ken wonders if the ketogenic diet has the potential to have strong therapeutic effects for other inflammatory conditions as well. Ken asks what other conditions Dom thinks might benefit from therapeutic ketosis. [00:14:02] Dawn mentions that Dom has been busy since his last appearance on STEM-Talk, having authored or collaborated on more than 40 papers, one of which garnered a lot of attention and was published in Frontiers in Neuroscience. This paper investigated whether therapeutic ketosis via ketone esters could represent a viable way to treat epilepsy and other seizure disorders. Dawn asks Dom to elaborate on this paper's findings and their significance. [00:16:26] Ken mentions that those listeners who are unfamiliar with ketone esters may want to check out our interview with Dr. Brianna Stubbs. Ken asks Dom to give a quick primer on ketone esters and why so many researchers in the field are excited about their potential. [00:19:20] Ken mentions that in addition to ketone salts and ketone esters, there are other product formulations out now, like the one from a company called Kenetik. Ken asks Dom what he thinks about this formulation. [00:23:33] Dawn mentions that Dom has had a number of animal studies published since 2019 looking at ketone induced neuroprotection and asks Dom to give an overview of some of this...

Tommy Wood in a Medical Doctor, Assistant Professor of Pediatrics and Neuroscience at University of Washington and IHMC visiting scientist, as well as consultant to Hintsa Performance´s Formula-1 drivers and other high performing individuals. I will be discussing with Tommy about the neurobiological basis of human performance and energy - and will also be diving to the science and practical implications of belief and placebo.

Today's interview is with IHMC's Dr. Gwen Bryan, a research scientist who investigates wearable robotic devices aimed at augmenting human performance in clinical, occupational, and military applications. She is particularly focused on maximizing the benefits of powered exoskeletons. At IHMC, Gwen leads the exoskeleton team, which is developing a novel augmentative device that continues IHMC's research on mobility devices for people with spinal cord injury. The team also is researching a powered exoskeleton to aid government employees whose work involves nuclear site remediation. Gwen and her team's effort, which utilizes a human-centered research approach, is uniquely situated to expand exoskeleton research and technology because of the expertise and collaboration that's available among IHMC's robotics and human-performance research groups. Gwen joined IHMC after completing her Ph.D. in the Stanford Biomechatronics Lab. Outside of work, Gwen enjoys soccer, weightlifting, painting and snowboarding. She also is a dog mom to two very adorable shelter dogs, Bandit and Oreo. Show notes: [00:02:32] Dawn asks Gwen what it was like growing up in Albuquerque, New Mexico. [00:03:02] Dawn mentions that it seems science was a part of Gwen's life early on. Dawn goes on to mention that Gwen's father was an engineer, and her mother was a nurse and asks how her parents having these backgrounds influenced her. [00:03:35] In addition to a science background, Gwen's mother is also a clarinetist who instilled a love for the arts in Gwen.  Dawn asks Gwen about her painting and how art benefits other aspects of her life. [00:04:17] Ken asks Gwen what she was like as a kid. [00:04:59] Ken asks Gwen to talk about a rafting trip she took with her cousin through the Grand Canyon. [00:06:27] Dawn asks Gwen how chocolate chip cookies factored into her third-grade science fair project. [00:08:04] Dawn mentions that fitness became a part of Gwen's life following an injury she had as a senior in high school. Exercise, particularly weightlifting, helped alleviate her back pain. Dawn asks Gwen what her fitness journey taught her about her body, and ultimately, how that experience gave her insights into the work she does today. [00:09:16] Ken asks Gwen how she chose to go to the University of Texas in Austin. [00:10:38] Dawn mentions that Gwen transferred to the University of New Mexico for her undergraduate work. Dawn asks Gwen what motivated her to apply her interest in mechanical engineering into robotics. [00:11:28] Ken asks Gwen what was involved in her transfer from the University of Texas to New Mexico. [00:12:34] Ken asks Gwen what led her to the Stanford Biomechatronics Lab. [00:13:38] Ken asks Gwen to talk about her internship with the Sandia National Research Labs. [00:14:40] Dawn shifts to talk about Gwen's current research focus on wearable robotics, particularly exoskeletons, mentioning that when the public hears this term most people generally think either insect exoskeletons or Ironman. Dawn asks Gwen to describe the exoskeletons she works on. [00:15:25] Dawn mentions that the potential uses of exoskeletons to help people with limited or no lower-limb mobility seems, in some respects, clear, but the application has been limited, and asks why that is. [00:16:40] Dawn asks what some other applications of exoskeletons are that are important to know about. [00:18:35] Ken mentions that during Gwen's doctoral work at Stanford, she developed the first cable-driven exoskeleton to assist all the three leg joints — hips, knees, and ankles — and asks Gwen to talk about how that design was developed and what made it special in the exoskeleton field. [00:20:10] Ken explains that Gwen's work also developed novel control systems for exoskeletons by using feedback from real-time physiological measurements of the user – coined human-in-the-loop optimization (HILO).

Our guest today is Dr. Dan Pardi, the CEO of humanOS.me, a digital health training application. Dan is well-known for his research into sleep and has collaborated with many high-performing organizations, from Silicon Valley venture capitalists to companies like Adobe, Salesforce, Workday, Pandora, Intuitive Surgical, and more. He also works with several branches of the U.S. Military to help elite warfighters maintain vigilant performance in both combat and non-combat conditions. Dan's podcast, humanOS Radio, is the official podcast of the Sleep Research Society, the Canadian Sleep Society, and a content partner of the Buck Institute on Aging. Dan collaborated with more than 100 science professors around the globe to create his digital humanOS application. Dan has a Ph.D. in cognitive neuroscience from Leiden University in the Netherlands and Stanford University in the United States. He has a master's degree in exercise physiology from Florida State University and currently lives in Austin, Texas, with his wife, two young boys, and their dog, Wally. Joining STEM-Talk host Dr. Ken Ford for today's conversation with Dan is Dr. Marcas Bamman, a senior research scientist here at IHMC. Marcas was a STEM-Talk guest on episode 116. In today's interview with Dan, we cover his early career in bioinformatics and how a trip to Moscow led to his doctoral research of sleep and treatments for narcolepsy. He also talks about the Loop Model to Adopt and Sustain Health Behaviors, a program he developed during his Ph.D. studies. The Loop Model became the core of his company, humanOS. Finally, Dan talks about the concepts of “actual health,” health-performance experts and a shift in what aging means, which he believes is important to improving the quality of life for all of us. Show notes: [00:03:19] Marcas starts the interview by asking Dan to talk about his years growing up in Northern California's Marin County. [00:04:06] Ken asks Dan about building radio-controlled cars with his father. [00:05:11] Marcas explains that Dan's father was a successful businessman who, after a successful career as a salesman for Remco selling kitchenware, started his own company in California that grew to 200 employees. Dan has been quoted as saying that one of the lessons he learned from his father was the value of relationships. Marcas asks how that lesson has affected Dan's life. [00:06:29] Dan talks about his passion for basketball and how his time at the Cap Lavin camp influenced his early life. [00:08:15] Marcas mentions that Dan's “science life” seems to have begun with a seventh-grade science-fair project that ended up landing him a job with Nike. Marcas asks Dan to talk about that story. [00:09:26] Ken mentions that Dan went to the University of San Francisco for his bachelor's degree and then went to Florida State for his Masters in Exercise Physiology. Ken asks what led Dan to FSU. [00:10:26] Ken asks why Dan decided to pursue a career in cancer research, going to work at the Preventive Medicine Research Institute in Northern California after graduating. [00:12:04] Marcas commends Dan for being ahead of his time by leveraging the new technological development of the internet portal to empower life scientists while he was working with the Bioinformatics Biotech DoubleTwist, and asks what that experience was like. [00:13:41] Ken asks Dan how a trip to Moscow led Dan to pursue a Ph.D. at Leiden University and Stanford, after already working in the industry for 10 years. [00:15:17] Marcas explains that Dan's Ph.D. research at the Zeitzer Circadian Biology Lab at Stanford University focused on gamma-hydroxybutyrate (GHB), sleep and ingestive behavior. Marcas asks what was most interesting about this research for Dan. [00:16:24] Marcas asks about a randomized controlled trial that Dan conducted to look into ecologically relevant amounts of sleep loss. This trial enrolled 50 participants and manipulated ...

In this episode, Dr. Preston Cline and Dr. Art Finch talk about the types of people who choose the hard path. Where do they excel, where do they struggle, and why don't they quite fit in with “normal” People. We focus on different learning and motivation profiles as well as the transitions between the routine and critical worlds.   COL(R) Art Finch, Ph.D., spent over 23 years providing psychological insight to the leading Special Operations and Tactical Law Enforcement organizations in the world. He is a graduate of U.S. Army Airborne, SERE, and Ranger Schools with more than 20 combat deployments to both Afghanistan and Iraq. He retired at the rank of colonel. created personality profiles for more than 10,000 candidates in support of assessment and selection events. Art continues to be licensed to practice psychology in North Carolina and in addition to serving as the Director of the newly formed Mission Critical Psychology Division at MCTI, he also serves as a Research Scientist with IHMC and The Gauge Group, a psychological consulting and executive coaching firm and is the founder and president of The Gauge Group has led leadership consultation and executive coaching for Fortune 100 tech companies; led assessment and selection support for Major League Baseball and National League Football; conducted high-stakes, high-performance psychological support for elite athletes; and assessment and selection psychological support for FBI, HRT and New York State Police SWAT team.   

Baker acts, bathrooms at Veterans Park, Whiting Field, IHMC and fire training budgets.

Today we would like to introduce you to one of our newest colleagues here at IHMC,  Dr. Kaleen Lavin, a research scientist who investigates the molecular mechanisms by which the body adapts and reacts to stressors such as exercise, training and aging. Kaleen came onboard at IHMC last year and is known for her use of computational biology techniques as a means to understand and improve human health, performance and resilience. She also is interested in the use of exercise as a countermeasure for a range of disease conditions, including neurodegenerative diseases such as Parkinson's disease. Today we will talk to her about some of her most recent work that examined the molecular effects of exercise training in skeletal muscle and in people with Parkinson's. We also talk to Kaleen about her recent paper that took a comprehensive look at the current literature surrounding the molecular and cellular processes underlying the molecular benefits that exercise induces in humans. The paper appeared earlier this year in Comprehensive Physiology and was titled, “State of Knowledge on Molecular Adaptations to Exercise in Humans.” Kaleen is a graduate of Georgetown University, where she earned a bachelor's degree in biology. She also earned a master's in sports nutrition and exercise science from Marywood University in Pennsylvania and a Ph.D. in human bioenergetics from  Ball State University in Indiana. Show notes: [00:03:02] Dawn opens the interview mentioning that Kaleen grew up in Scranton, Pennsylvania, and asks Kaleen about her passion for music as a youth. [00:03:25] Ken asks Kaleen about her high school years and how she became  a competitive swimmer. [00:04:26] Dawn mentions that Kaleen was an excellent student growing up, but that it wasn't until her junior year of high school that she became interested in science. Dawn asks if it were a teacher who inspired Kaleen. [00:05:21] Dawn asks what led Kaleen to attend Georgetown University after graduating from high school. [00:05:57] Dawn asks if Kaleen knew she wanted to major in biology when she first arrived on campus at Georgetown. [00:06:45] Ken asks about Kaleen's experience of becoming a part of the Howard Hughes Program at Georgetown, which led to her gaining experience working in lab. [00:08:47] Dawn mentions that Kaleen transitioned from competitive swimming to running during her undergraduate years, running a marathon and half marathon. Dawn asks if  Kaleen's father, who is an avid marathoner, gave her the incentive to start signing up for marathons. [00:13:19] Dawn asks Kaleen about a faculty advisor who noticed her passion for running and exercise and helped her decide what to pursue for her master's degree. [00:15:23] Ken asks Kaleen what led her to pursue her master's at Marywood University, a small Catholic University in Scranton. [00:16:56] Ken asks Kaleen what prompted her to pursue a Ph.D. in exercise science at Ball State University, which has one of the longest-standing human performance programs in the country. [00:17:57] Dawn mentions Kaleen's experience with no-breath laps as part of her training when she was in high school on the swim team. Dawn asks Kaleen to explain what no-breath laps are. [00:19:00] Dawn asks Kaleen about a study she conducted for her master's thesis at Marywood that examined the effects of controlled frequency breath swimming on pulmonary function. [00:22:13] Ken asks about how Kaleen's time at Ball State set her up for her post-doc work at Center for Exercise Medicine at the University of Alabama at Birmingham. [00:24:31] Ken asks what it was about UAB that attracted Kaleen to do her post-doc work there. [00:26:08] Dawn asks about a study published in 2017 by a group at UAB led by Marcas Bamman where researchers took people with Parkinson's disease and ran them through a high-intensity exercise program, finding that you could not only help people preserve some function but al...

Registration for IHMC's 2022 Summer Robotics Camp is open for the Pensacola campus. Rising eighth-, ninth-, and 10th-graders can register to spend a week learning about computer programming and robots.  Shannon Nickinson has the details.

durée : 01:58:32 - Le 7/9 - par : Nicolas Demorand, Léa Salamé - Bernard Guetta, député européen, Pascal Ory, historien, auteur de « De la haine du Juif » (Bouquins), et Nicolas Offenstadt, historien, maître de conférences à l'Université de Paris 1, co-fondateur du Comité de vigilance sur les usages publics de l'Histoire, sont les invités du 7/9 de France Inter. - invités : Bernard Guetta, Pascal Ory, Nicolas Offenstadt - Bernard Guetta : député eurpéen, Pascal Ory : Professeur émérite d'histoire contemporaine à l'université Paris 1 Panthéon-Sorbonne, Nicolas Offenstadt : Historien, maître de conférences à l'université Paris 1 Panthéon-Sorbonne, membre de l'Institut d'histoire moderne et contemporaine (IHMC), spécialiste de la Grande Guerre

Our guest today is Dr. Morley Stone, the former Chief Technology Officer for the Air Force Research Laboratory (AFRL) and former Senior Vice President for Research at Ohio State University, who is now IHMC's Chief Strategic Partnership Officer. Morley is recognized as an international leader in biomimetics and human performance. In today's interview, we talk to Morley about his time as AFRL's chief technology officer as well as his stint as the chief scientist for the Air Force's 711th Human Performance Wing, which is responsible for providing technical oversight of projects geared to optimize human performance for the nation's air, space, and cyberspace forces. We also have a fascinating conversation with Morley about his early career and research into biomimetics, which is the study of using biological structures, materials and principles as models for the development of new materials, structures, and devices. In his new role at IHMC, Morley will become the institute's point person for public- and private-sector partnerships. He also will work with IHMC's scientists and research staff to help coordinate and implement the multitude of scientific projects the institute has in its pipeline. Show notes: [00:03:07] Dawn mentions that Morley grew up in a small steel producing town in Pennsylvania and asks him what he was like as a kid. [00:03:56] Ken asks Morley about his days as wrestler growing up and why he still today views wrestling as a special sport. [00:05:00] Dawn asks about Morley's move to Dayton, Ohio, when he was 17. [00:05:36] Dawn asks how Morley decided upon Wright State as opposed to the University of Dayton. [00:05:57] Morley tells the story of how a girl in college pointed out an ad for an internship and how that helped him decide to become a biochemistry major. [00:06:43] Dawn asks what happened to the girl who pointed out the aforementioned ad. [00:08:28] Ken asks Morley to talk about the Air Force Research Lab (AFRL) and the role of the lab's Materials and Manufacturing Directorate. [00:09:53] Dawn mentions that after earning his bachelor's degree, Morley had a short stint as a materials research engineer at the directorate before heading off to Carnegie Mellon University to work on a Ph.D. in biochemistry. Dawn asks why Morley chose to attend Carnegie Mellon. [00:11:08] Dawn mentions that in the late ‘80s and early ‘90s, Morley had the good fortune to work with scientists who had the foresight to know that there was going to be a radical change in material science, which up until that point had been dominated by metals and ceramics. Morley talks about the most important lessons he learned from these colleagues and mentors. [00:12:41] Dawn asks about Morley's time as a research biologist, and eventually principal research biologist, at the Materials and Manufacturing Directorate after his Ph.D. [00:14:41] Ken asks Morley to explain biomimetics and discuss the systems that Morley and his colleagues looked at during his time at the Materials and Manufacturing Directorate, ranging from infrared sensing to instances of biological camouflage. [00:18:01] Dawn mentions that the creation of nanoscale materials for advanced structures has led to a growing interest in the area of biomineralization, she goes on to say that during Morley's time at the directorate, he especially researched the process of biomineralization and the assembly of nanostructured inorganic components into hierarchical structures, which led to the development of a variety of approaches that mimic the recognition and nucleation capabilities found in biomolecules for inorganic material synthesis. Morley discusses his 2002 paper in Nature Materials where he described the in vitro biosynthesis of silver nanoparticles using silver-binding peptides. [00:21:20] Dawn asks about Morley's 2004 paper in Advanced Materials where he and his colleagues had taken a protein that was responsible for thermal sensi...

Dr. Marcus Bamman joins Andrew McKay for the Pensacola Morning News to discuss the programs at IHMC. IHMC is a not-for-profit research institute of the Florida University System and is affiliated with several Florida universities. They want to learn from the studies done on the healthy young military to see how bodies respond to stressors and anxiety. How does the body react to certain environmental exposure? This new field also researches oxytocin and the effects on the human body during stressful conditions. IHMC is currently looking for individuals to help with research. The IHMC Story

In today's episode, Dr. Tommy Wood returns for his fifth appearance on STEM-Talk. Tommy is a UK-trained physician and an assistant research professor of pediatrics at the University of Washington. He also is a visiting research scientist and a valued colleague of ours here at IHMC. Today's interview focuses on a new paper that Tommy just had published by the American Society for Microbiology. It's titled, “Reframing Nutritional Microbiota Studies To Reflect an Inherent Metabolic Flexibility of the Human Gut: A Narrative Review Focusing on High-Fat Diets.” We discuss the paper and follow up on some research Tommy has done since his last appearance on STEM-Talk, a two-part interview that took place a little more than a year ago. In that two-part interview, episodes 110 and 111, we touched on Tommy's research into the importance of metabolic health and how only one in eight Americans is considered metabolically healthy. We also talk to Tommy about a new grant he just received to examine the effects of azithromycin on premature brain injury in a ferret model. As part of this grant, Tommy will be collaborating with his wife, Dr. Elizabeth Nance, who also is an assistant professor at the University of Washington and was our guest on episode 71 of STEM-Talk. Show notes: [00:03:15] Dawn opens the interview mentioning Tommy's new paper published by the American Society for Microbiology titled “Reframing Nutritional Microbiota Studies to Reflect an Inherent Metabolic Flexibility of the Human Gut: A Narrative Review Focusing on High-Fat Diets.” Dawn mentions that in our last interview with Tommy, he talked about the importance of insulin sensitivity and metabolic health, yet as Tommy has pointed out, more than 80 percent of Americans have some kind of metabolic disease or dysfunction. Given that, Dawn asks Tommy to revisit key points regarding insulin resistance; the importance of metabolic health; and why so many Americans struggle with this issue. [00:06:18] Ken points out that the common view held in much of the nutritional-microbiota research is that high-fat diets are harmful to human health, at least in part through their modulation of the gut microbiota. Ken goes on to say that there are a number of studies that support the inherent flexibility of the human gut and our microbiota's ability to adapt to a variety of food sources, suggesting a more nuanced picture than the commonly held view. Ken asks Tommy to give an overview of the gut microbiome and how research in the past decade has explored the effects of the gut microbiome on our metabolism, immune systems, our sleep, and our moods and cognition. [00:09:50] Dawn asks Tommy to explain the history of how fat, and high-fat diets, became public enemy number one in many circles, including gut microbiome research. [00:12:46] Ken mentions that there are many limitations when it comes to preclinical nutritional research, with many studies on the role of fat in the diet being based on animal models, particularly rat models, which presents several problems since the natural diet of a mouse is low in fat and high in carbohydrates. [00:15:50] Ken asks Tommy about the need for a more nuanced view of fat and our microbiota's ability to adapt to different food sources. [00:17:33] Ken points out that while people might throw around the term “healthy gut microbiota,” the research into the gut microbiota is so new that we don't yet know for sure what a healthy gut microbiota should look like. [00:21:22] Ken asks Tommy how we should go about reframing the debate about fat and high-fat diets to better reflect the overall evidence. [00:23:48] Dawn mentions that in the past decade, researchers have significantly improved our understanding of the gut microbiome. She asks about Tommy's belief that there is a need to understand the gut microbiome in an evolutionary context as well. [00:25:18] Tommy gives an overview of the gut-barrier function and its role in ...

Our guest today is Dr. Christoffer Clemmensen, an associate professor and lead researcher at the University of Copenhagen's Novo Nordisk Foundation Center for Basic Metabolic Research. Christoffer's lab at the university explores pharmacological and therapeutic treatments for obesity and its related diseases and disorders. He and his colleagues focus on dissecting the neuroendocrine signals involved in coordinating appetite, food-motivated behavior, energy expenditure, glycemic control, and lipid metabolism. We have a fascinating discussion with Christoffer about his lab's efforts to turn molecular and physiological insights into innovative therapeutic strategies that Christoffer hopes someday can reduce obesity and its associated metabolic disorders. Christoffer is a native of Denmark who earned his Ph.D. in Molecular Pharmacology from the University of Copenhagen in 2013. Joining Ken for today's interview is IHMC colleague and senior research scientist Dr. Marcas Bamman, who was our guest on episode 116. Marcas is the founder and former director of the University of Alabama at Birmingham Center for Exercise Medicine.  Marcas joined IHMC last year as a Senior Research Scientist. Show notes: [00:03:24] Marcas asks Christoffer about growing up in a small rural town in Denmark in the 1980s and ‘90s. [00:04:05] Christoffer's talks about his days as an elite tennis player when he was a youth. [00:04:41] Ken asks Christoffer when he first became interested in science. [00:05:48] Marcas asks Christoffer what changed his mind about wanting to study computer science at university. [00:07:04] Christoffer explains how he decided to attend University of Copenhagen. [00:08:19] Marcas mentions that Christoffer's original focus at university was on exercise biology, but that he became fascinated by the mechanisms of obesity and that interest took him in a new direction. Marcas asks how that shift in interest came about. [00:10:01] Marcas follows up on the previous question and asks if there were a particular instance that persuaded Christoffer to switch from focusing on exercise to focusing more on weight control and obesity. [00:10:40] Ken asks what led Christopher to pursue a Ph.D. in molecular pharmacology after attaining a bachelor's degree in exercise biology and a master's degree in human biology. [00:12:11] Marcas asks Christoffer why he went to Munich, Germany, as a postdoctoral fellow at the Helmholtz Diabetes Center after completing his post-doc at the University of Copenhagen. [00:14:00] After mentioning that Christoffer eventually became the group leader at Helmholtz, Ken asks Christoffer why he then transitioned back to the University of Copenhagen. [00:14:52] Marcas asks Christopher to talk about the big questions that get to the heart of his research. [00:16:20] Ken mentions that Christoffer is now an associate professor at the Nova Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen, where he is the head of the Clemmensen Group. Ken goes on to mention that the Clemmensen Group's website says the lab focuses on dissecting the neuroendocrine signals that coordinate appetite regulation, food-motivated behavior, energy expenditure, glycemic control, and lipid metabolism. Ken asks if Christoffer could give an overview of what all these research focuses entail. [00:18:17] Marcas mentions that obesity and its related diseases, such as type-2 diabetes and cardiovascular disease, have become serious problems affecting the world's public health and global economy. Marcas goes on to say that Christoffer's 2019 paper titled “Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases” makes the observation that the treatments we have been using to deal with this problem have not been able to effectively reverse the staggering rates of obesity we're witnessing around the world.

durée : 00:51:56 - Le Cours de l'histoire - par : Xavier Mauduit, Maïwenn Guiziou - Le rire renouvelle sans cesse ses formes et ses modes d’expression. Le travail archéologique sur l’humour nous révèle notamment une valorisation de l’art de plaisanter et le sens aigu de nos ancêtres pour la répartie. Des Anciens aux Modernes, comment le rire et sa perception ont-ils évolué ? - réalisation : Esther Valencic, Somaya Dabbech - invités : Danielle Jouanna hélleniste et historienne; François Lavie membre de l’Institut d’histoire moderne et contemporaine (IHMC)

How much protein can one absorb per meal; Thru hiking, backpacking, and paleo/ketogenic diet; Keto Masterclass - Recalculate Macros; Pregnant or breastfeeding metabolic health; No issues Make your health an act of rebellion. Join The Healthy Rebellion Please Subscribe and Review: Apple Podcasts | RSS Submit your questions for the podcast here   Show Notes: News topic du jour: A giant solar farm sounds perfect, right? Not quite. 1. How much protein can one absorb per meal? [20:09] Leslie says: I am a 70-year-old female.  Paleo and low carb for many years. Avid podcast listener and book buyer - love all of yours!  Don't want any more sarcopenia than I already have.  Followed your advice and went on the Ketogains macro calculator that recommends about 100 gm protein per day.  But I'm also working on lowering insulin by only eating 2 meals per day.  Searching tells me that bodybuilders think they can only absorb 30 gm per meal.    I eat berries, collagen, protein powder (grassfed!), goat kefir and powdered multi vitamins mixed together along with 4 oz meat and 2 eggs for breakfast around 11 am.  For dinner I eat 4 oz meat with some Amy's organic soup and sometimes a salad.  I am not aiming for ketosis, just low carb. I could stand to lose a few pounds, but at 5'4" and 135 at my age I am OK but would like more muscle or at least not lose any more.  Should I add a third meal for some of the protein or perhaps redistribute the protein amounts?  Thanks! I do this workout about once a week, https://www.youtube.com/watch?v=dBbPsJKq9uM     1 hour of Zumba about 3-times per week and miscellaneous other exercises.  Before Covid I did more, including some blood-flow restriction  which seems to work on the same principle as the video I linked.  I feel like it takes about a week for me to recover enough to want to do the video workout again.  I don't do the lifting-the-bag part of the workout - my back isn't perfect.  I also recently added Esther Gokhale's daily workout (1,2,3 move) and should add the associated weight workout as well.  I liked Doug McGuff's concepts and have listened to the IHMC podcasts as well as Peter Attia's stuff.  Like I said, I am an avid podcast listener!! 2. Thru hiking, backpacking, and paleo/ketogenic diet [25:08] Matt says: I have been following a paleo diet for 5-6 years now, and transitioned to a ketogenic approach at the beginning of this year.  Since then I've been able to maintain a much lower  body weight than ever before in my adult life and my endurance and fitness levels (and to a lesser degree strength levels) have been better than ever before.  These past couple years I have gotten more into thru hiking and backpacking and have been planning some longer hikes and a long term goal of doing the entire appalachian trail.  My question is; to your knowledge is there anyone developing programs or templates on planning long hikes primarily utilizing ketogenic and paleo foods?  Everywhere you look when planning thru hikes the advice is largely the same (granola, oatmeal, instant mashed potatoes, and candy for 'energy'), but it seems obvious that 6 months on a trail requires primarily oxidative phosphorylation, and KD or paleo seems to be an obvious choice.  Information on the topic seems pretty slim, especially when it comes to planning and packing for at least a weeks worth of sustenance that would be necessary when out in the wilderness.  With as many ultra runners and endurance athletes beginning to tout the benefits of KD, I am wondering if there are any thru hikers doing the same thing? I don't know if you have addressed this in podcasts or blog posts in the past and I just missed it.  Seems like it could be an interesting topic, and maybe another area where some thought leaders can emerge. https://robbwolf.com/2020/08/17/fat-fueled-sheep-hunting-with-gina-shively-salty-talk-019-thrr/ 3. Keto Masterclass - Recalculate Macros? [28:59] Kyle says: Hello, I'm hoping to ask a quick question about the Keto Masterclass. I'm into my fourth week and feel I'm doing relatively well.  I've got a spreadsheet where I track all my food, stay on track well although I do have a Perfect Keto Whey shake for breakfast everyday.  Not ideal but helpful given my vocational and avocational commitments.  Four weeks in  and I've lost 8 pounds and am in nutritional ketosis based on measuring blood ketones.  One of the cookbooks I've picked up mentions recalculating your macros periodically.  I've done that and it drops my macros slightly based on weight loss to date.  Seems reasonable to me, but is this something you also recommend doing? Thank you for your consideration. Sincerely, Kyle 4. Pregnant or breastfeeding metabolic health [32:57] Becky says: First off, screw any haters you get for your "salty" rants in The Healthy Rebellion Radio. More people with platforms like yours need to speak out. The hypocrisy, the nonsensical rules (bars are open but kids can't go to school), the suppression of seemingly effective CHEAP widely available prophylaxis and treatments....its all SO INFURIATING and it is so good to hear both of you question what is happening on your platform. THANK YOU. I've unfortunately had to distance myself from a few health "influencers" that I once really respected who have gotten very SJW and holier than thou this past year, so I am thrilled that I finally started listening to your podcast and seem to have found some kindred spirts. Definitely makes me want to join the Healthy Rebellion too, which brings me to my question... I am 37, work out moderately (strength training 2-3 times a week, trail running or walking 1-2 times a week), get lots of outside time, pretty good sleep, and eat 80-20 primal (stick to whole foods, but will indulge in ice cream, white rice, or other no-nos on occasion). The primal eating with a focus on protein and fat has done wonders for my hunger and "hangry" symptoms, which used to be a constant plague (who knew that a breakfast of Cheerios, skim milk, and a banana did not a satiating meal make). However, I've always been about 20 lb overweight, and still feel the need to eat every few hours to avoid irritability, brain fog, and shakiness. This tells me I'm definitely not metabolically healthy, which is my ultimate long-term goal (although weight loss would also be nice). However, I'm currently 6 months pregnant with my second child. I plan to breastfeed this little guy for around 2 years like I did my first, who I weaned when I was about 10 weeks pregnant. In other words, I've been either pregnant or nursing now for the last 3.5 years, pretty much ever since I discovered "Wired to Eat" and a more paleo lifestyle. Healthy pregnancy and breastfeeding are my top near-term priorities, therefore I don't think doing something like going full keto would be right for me, but I would love to start the journey towards better metabolic health. Where should I start? And, related to the Healthy Rebellion, I'd love to join but am not sure it will be worth it in the near-term given my current maternal journey. Are there resources in THR that would apply to pregnant or breastfeeding mamas as well? Thanks, -Becky PS One of the things I've struggled with a lot through both pregnancies and breastfeeding has been a feeling of dehydration. I would have mornings where I woke up feeling hungover when not a drop of alcohol had been had the night before. I got a LMNT free sample pack about a month ago and LOVED IT. I feel such a huge difference in energy, thirst, and a lack of headaches. This is exactly the product I've been looking for since moving to the tropical island where I now live! Thank you! https://lilynicholsrdn.com/real-food-for-pregnancy/ 5. No issues [38:02] Park says: Hey, I've been listening to a variety of podcasts over the last ten years and it's always amazing to me how many people have issues with so many foods or can't lose fat or have low testosterone, etc. Without sounding like a giant douche, I think it's time we hear that someone has no issues and everything is fine. I'm 62 and have no idea what my testosterone is or my LDL or any metric. I drink  too much beer, but despite this I'm lean and my libido is humming along nicely. I've done IF for almost ten years,  eat mostly paleo-ish and do compound movements three days a  week. I realize it's oversimplification to assume that my protocol should work for everyone else, but damn, it's so shocking that so many people seem to struggle. When people chime in with their protocols, are they not being entirely truthful? It seems that the basics should work more often than they do. Sponsor: The Healthy Rebellion Radio is sponsored by our electrolyte company, LMNT. Proper hydration is more than just drinking water. You need electrolytes too! Check out The Healthy Rebellion Radio sponsor LMNT for grab-and-go electrolyte packets to keep you at your peak! They give you all the electrolytes want, none of the stuff you don’t. Click here to get your LMNT electrolytes Transcript: Download a copy of this transcript here (PDF)

This podcast interview focuses on product innovation that has the power to avoid people that get paralyzed from having to start their lives over. My guest is Mark Daniels, Florida Institute for Human and Machine Cognition.Mark Daniel was born and raised in Pensacola. He injured his spine almost 13 years ago and have been using a wheelchair since. In 2010, Mark was asked to assist IHMC with evaluating their first powered exoskeleton, and he kept this involvement since.He has now joined IHMC as a full time research intern to work on the design, fabrication, and testing of the exoskeleton for the Cybathlon. Mark anticipates the Cybathlon to make a huge stride in technology and awareness to improve quality of life for those with loss of mobility due to injury or illness across the world. "Every day I am confronted with the reality that I am paralyzed. Every day I face this reality to find comfort in my abilities and not anger in my disability – we all have disabilities and I encourage everyone to live unrestrained.” This inspired me, and hence I invited Mark to my podcast. We explore the world of Exoskeleton, the major advances over the last 10 years and how the blend of hardware, software and active user involvement has been fundamental to this.We discuss what the innovation should be really all about, how to accelerate it, and what mental obstacles one has to overcome to come out as a winner. Here are some of his quotes:I look at everything that we're doing here at IHMC and all the other exoskeletons, and the other technology that is giving mobility back to people with disabilities. I look at all of this as hopefully, that 18 year old kid that I was. An accident will happen to him, and he will get paralyzed. And some of the technology that I'm working on or helping to push or develop will be what he's given whenever he has the same problem that I did. And he'll go back to the same job that he had and he won't have to start his life over.We notice who makes strides in the market, and who wins in that market. And it's the people that pay attention to the feedback of their end user. And the way to do that is to get somebody that's gonna want your technology and then give them a reason to want it.During this interview, you will learn four things:Why it is key to create solutions that smartly balance working with you, as much as for youThat users have alternatives – sometimes radically different from what you offer. And to make them want to change you have to deliver a shift in value.Why it is key to not argue with a user whether what they want is a good idea or not. That art and technology are not that different – and that’s where the opportunity hidesFor more information about the guest from this week:Mark DanielsWebsite IHMC See acast.com/privacy for privacy and opt-out information.

Julie Sheppard, Executive Vice President and Chief Legal Counsel at IHMC, joins the Pensacola Morning News to discuss the $6 million grant from Triumph Gulf Coast that will fund continued research focused on the human health span, resilience, and performance.

Katherine Eban’s recent book, “Bottle of Lies,” reveals that nearly 80 percent of the active ingredients of all brand-name and generic drugs as well as almost all of the antibiotics in the U.S. are made outside of the country, mostly in China and India. Eban is an investigative journalist who has written award-winning stories that range from pharmaceutical counterfeiting to gun trafficking. “Bottle of Lies” is a New York Times bestseller that came out in 2019. On June 17, 2020, Katherine Eban gave a talk for TEDMED, a series of TED talks that focus on health and medicine. Their mission is to connect science and the public by sharing stories that inform, inspire, engage and provoke action. Next up are 12 minutes of excerpts from a one hour interview with Katherine Eban by Ken Ford and Dawn Kernagis. Kernagis is a Research Scientist and Ford is Founder and CEO of the Florida Institute for Human & Machine Cognition (IHMC). The full interview is posted on the YouTube channel of the IHMC. They spoke with Katherine Eban on March 12, 2020, about the dangers associated with relying on generic drugs manufactured overseas.

Our guest today is Dr. Marcas Bamman, an internationally recognized researcher known for his scientific contributions to the biology of human skeletal muscle and medical rehabilitation. Marcas recently joined IHMC as a Senior Research Scientist. He is the founder and former director of the University of Alabama at Birmingham Center for Exercise Medicine. Marcas and the UAB center are recognized as world leaders in the biological mechanisms underlying exercise-induced adaptations and their clinical utility in disease prevention, treatment and rehabilitation. At IHMC, he will expand his research aimed at maximizing the performance and resilience of elite warfighters. One of Marcas’ first projects at IHMC is working with the institute’s Chief Science Officer Tim Broderick on a DARPA-sponsored program. This research is aimed at developing a revolutionary platform to enhance training and resilience of elite service members. Tim talked about the program, called the Peerless Operator Biologic Aptitude project, during his interview on episode 112 of STEM-Talk. In today’s interview, we talk to Marcas about the Peerless project as well as his earlier research into the many ways that exercise and strength training can induce a multitude of health benefits. Show notes: [00:03:11] Dawn opens the interview by asking Marcas where he grew up. [00:03:21] Dawn asks Marcas what sports he played given that he is now an exercise scientist. [00:03:45] Dawn mentions that in addition to being good at basketball and soccer in high school, that Marcas was also good in his chemistry and mathematics classes. [00:04:47] Dawn asks if it is true that Marcas was the sports editor of his high school newspaper. [00:05:25] Dawn asks Marcas why he decided to pursue science despite having a promising future as a sportswriter. [00:06:08] Ken asks if Marcas decided to attend Kansas State University after high school because it was the same school his father had attended. [00:06:59] Ken asks what led Marcus to the University of Alabama Birmingham for his master’s degree. [00:08:09] Dawn asks if it is true that Marcas met his wife Deanna in a fitness center. [00:09:00] Marcas explains the non-traditional rout he took to earning his doctorate at the University of Florida. [00:14:05] Dawn mentions that while Marcas was working at NASA, he worked on a study that had people go through 14 days of bedrest in an effort to mimic space flight. The resulting paper appeared in Medicine and Science in Sports and Exercise and was titled, “Resistance Exercise Prevents Plantar Flexor Deconditioning During Bed Rest.” Dawn asks about the study and its findings, as well as how Marcas was able to convince people to spend 14 days in bed. [00:19:47] Marcas explains how he ended up back at UAB following his dissertation. [00:20:32] Ken asks what Marcas’ overarching question was that drove his research when he began his career at UAB. [00:22:24] Dawn mentions that Marcas has played a major role nationally in the recognition and growth of exercise medicine. Dawn asks how Marcas first became interested in this concept of exercise as medicine. [00:24:06] Dawn asks Marcas to talk about his research that has shown that exercise can help prevent and delay health problems, and that different types of exercise can bring about different health benefits. [00:29:38] Dawn mentions that in 2011 Marcas established the University of Alabama Birmingham Center for Exercise Medicine (UCEM), which has become well known nationally as a leader in exercise medicine. Marcas gives an overview of how the center came about and the research that is conducted there. [00:34:23] Marcas gives an overview of a clinical trial he conducted in 2011 which showed that men and women in their 60’s and 70’s who underwent supervised weight training developed muscles that were as large and strong as those of the average, untrained 35- to 40-year-old.

Katherine Eban’s recent book, “Bottle of Lies,” reveals that nearly 80 percent of the active ingredients of all brand-name and generic drugs as well as almost all of the antibiotics in the U.S. are made outside of the country, mostly in China and India. Eban is an investigative journalist who has written award-winning stories that range from pharmaceutical counterfeiting to gun trafficking. “Bottle of Lies” is a New York Times bestseller that came out in 2019. On June 17, 2020, Katherine Eban gave a talk for TEDMED, a series of TED talks that focus on health and medicine. Their mission is to connect science and the public by sharing stories that inform, inspire, engage and provoke action. Next up are 12 minutes of excerpts from a one hour interview with Katherine Eban by Ken Ford and Dawn Kernagis. Kernagis is a Research Scientist and Ford is Founder and CEO of the Florida Institute for Human & Machine Cognition (IHMC). The full interview is posted on the YouTube channel of the IHMC. They spoke with Katherine Eban on March 12, 2020, about the dangers associated with relying on generic drugs manufactured overseas.

Jerryll is a seasoned Engineer and scientist in the fields of robotics research and development to help mankind. He worked with institutions like NASA, IHMC, and IIT, helping paraplegic people gain mobility through robotic exoskeletons. After the government refused to fund these institutions for further technology development he decided to take things into his own hands. He then started a real estate investing company and later on a SEO for real estate investors company that both became highly successful to continue his research to develop solutions to those with mobility restrictions through robotics technology. Now he flips 3 to 5 houses at a time and helps other investors claim the #1 spot on Google and increasing their conversions through his in-house developed credibility strategies. Jerryll@SEOForRealEstateInvestors.com http://seoforrealestateinvestors.com/ https://twitter.com/JerryllSeo https://www.instagram.com/webuyhousesinconnecticut/ https://www.facebook.com/JerryllSEO --- Support this podcast: https://anchor.fm/crushingitinrealestate/support

Wheelchair Life to the Exoskeleton, Human Robotics Lifestyle:I began my exoskeleton pilot certification in 2007 at the age of 18. In 2010, I was introduced to the Florida Institute for Human and Machine Cognition (IHMC) where a team of engineers and computer scientists had developed MINA, their first paraplegic mobility device or exoskeleton. Over the last decade, we have worked together to develop hardware capable of mimicking the human gate and necessary software to drive it. We are currently weeks away from testing our 4th iteration exoskeleton, QUIX, as a part of our participation in Toyota's Mobility Unlimited Challenge after we compete in the 2020 Cybathlon later this year. It has been an honor to witness the advances in technology and evolution of handicap sports. In response to witnessing these miraculous achievements, I have spent the past 13 years of my life pushing the limits of the wheelchair that certified me for this opportunity. What I thought would ruin my life has given me more than I ever could have earned on my own two feet. Quote: How many stairs?Mark Daniel, Pilot Designer, evaluator, and user representative, Mark was born and raised in Pensacola. As a young adult, he graduated high school early and pursued a career in ironwork. First going to trade school for diesel mechanics, then learning how to weld and fabricate. In 2007, at eighteen years old, Mark started his career and began planning his next steps. Working long hours in risky conditions was exciting at first, but after five months the work took its toll. He fell asleep driving home, flipping his SUV several times, and awoke in the ICU of a local hospital. After learning of his paralysis, he set out to regain his independence. In 2010 Mark evaluated IHMC's first iteration exoskeleton, and again in 2013 for the second. In February 2016 he rejoined the team as a research intern to evaluate the third iteration and prepare for the Cybathlon. Mark placed second in the Cybathlon, winning the silver medal. Since the Cybathlon he has taken on the American Discovery Trail, which covers 4,834 miles from the Atlantic coast in Delaware to the Pacific in San Francisco.   Top 3 Hot Point Takeaways:What it takes to relearn a new way of the young adult life. Learning the teamwork to create something to help others with. Remember to leave behind your worries to create a more positive future.   Today’s Resource Links from the Podcast:http://helpquix.org https://helpquix.org/our-pilot www.youtube.com/channel/UCCJktumbjjRHiHPMaJd8zc wwww.youtube.com/user/TheIHMC www.youtube.com/user/DRCihmcRobotics   Watch us on YouTube:https://youtu.be/-XUDMJwbDB0   Timestamped Show Notes:00:30 - Introduction 11:45 - Accidents come along. From the outside looking in, even in my position at the moment, looking at the situation that I was in, it seems like a huge detriment for me. 18-years-old, just starting my adult life, then for the accident to happen, have to restart and figure it all out all over again. But you know, I'm 31 now, it'll be 13 years in October, and, and really, looking back at the situation, it couldn't have come at a better time. I say that at 18 years old, I figured out my life, I had a career plan, I was on that plan, and I was moving forward. But I mean, really looking at the experiences up till then I grew up riding dirt bikes, go-karts, four-wheelers, skateboards, bicycles, running through the woods, fishing, hunting, you know, the good, healthy, youthful adrenaline life. 20:00 - In 2010 and I met all of the engineers and everybody working on the project. There were so many different engineers, interns, and all that have worked on the project in and out, but we really just have an awesome team here. I've been graced to work with them all really, I mean, all the people that I work with here, there's Tyson in the glasses there on the right, Peter on the left, and that's Jeremy. All these people that I've known for so...

It’s that time again for another Ask Me Anything episode. And we must say, listeners sent us a wealth of excellent questions for this round of Ask Me Anything. In today’s podcast, Ken and Dawn answer questions that range from blood-flow restriction to swimming induced pulmonary edema to intermittent fasting to methylene blue to low-carb diets, and much, much more. If you have questions you want to send to Ken and Dawn for an Ask Me Anything episode, email your question to STEM-Talk Producer Randy Hammer at rhammer@ihmc.org. Show notes:  [00:02:24] In light of Ken’s former experience in wrestling, a listener asks about wrestlers who perform neck bridges to strengthen their neck.  The listener wonders if Ken thinks neck exercises are important and, if so, what does he does in that regard. In his response, Ken mentions a neck-strengthening device, Iron Neck. [00:06:12] A listener asks Ken and Dawn about their morning routines and what scientific journals they read and if they could each give a few book recommendations. [00:08:16] A listener asks Dawn, in light of her accepting a position at the University of North Carolina, if she will continue working with IHMC and  co-hosting STEM-Talk. [00:09:13] A listener asks if and how Dawn sees crossover between the research on humans in extreme environments that she did at IHMC, and the clinically oriented work she is doing now. [00:10:37] A listener mentions that they have recently started using blood-flow restriction training in their workouts thanks to STEM-Talk and have enjoyed the experience. The listener goes on to mention, however, that they are noticing they feel light headed when going for a run after a blood-flow restriction resistance workout. The listener asks Ken if he has any knowledge of this phenomenon, or other side effects of blood flow restriction exercise. [00:12:56] A listener mentions that they have just finished reading Denise Minger’s “Death by Food Pyramid” which explains that no nutrition-oriented classes are required for a Harvard medical degree, which is also true of about 70% of medical schools in the nation. The listener goes on to mention, from their own experience, that people are often told to consult their doctor when thinking about the potential benefits of new diets. Doctors and even nutritionists, however, generally prescribe the Mediterranean diet and do not seem to know much about low-carb diets. The listener asks Ken who one should consult when wanting to start a ketogenic diet. In his response, Ken mentions several resources, including the websites Virta Health and Diet Doctor; and the books “The Art and Science of Low Carbohydrate Living” as well as “The Art and Science of Low Carbohydrate Performance.” [00:15:22] A listener, who is a triathlete, asks Dawn for advice about performance in extreme environments, particularly in regards to swimming induced pulmonary edema. They also go on to ask about Dawn’s thoughts on Sildenafil, also known as Viagra. In her response, Dawn mentions a paper by Dr. Richard Moon of Duke University, “Swimming-Induced Pulmonary Edema: Pathophysiology and Risk Reduction with Sildenafil.” [00:20:08] A listener asks Ken a question about an article they read about a study out of the University of Glasgow that was published in Nature Scientific Reports. The listener highlights a quote from the press release announcing the publication of the article: “There is no magic diet, or magic food, for weight control. Instead, people have to find the best way to eat fewer calories. Low-carb diets have had a lot of hype from media and celebrities, but they are no better than high-carb diets. Their evidence is generally poor, and our earlier research found low-carb diets are associated with some vitamin deficiencies, with more diabetes, not less. We can't stop people cutting carbohydrate, and it may suit some people at least in the short-term, but there should be a health warning.

Today’s interview features Dr. Peter Pirolli, a colleague and senior research scientist here at IHMC since 2017.  He previously was a fellow at the Palo Alto Research Center (PARC) and is known for his research into human information interaction. Peter’s work on information foraging theory led to his book “Information Foraging Theory: Adaptive Interaction with Information.” Peter received his doctorate in cognitive psychology from Carnegie Mellon University in 1985 and throughout his career his research has involved a mix of cognitive science, artificial intelligence, and human-computer interaction. His current interests include disruptive mobile-health technologies for precision behavioral medicine to support healthy behavior. Right now, Peter is working closely with IHMC’s Chief Science Officer Tim Broderick on a DARPA project that Tim discussed in his recent STEM-Talk interview, episode 112. Peter also talks about the project and the work that he, Tim and others at IHMC are doing to increase the biologic aptitude of elite warfighters. In today’s interview, Peter also discusses his role as the principal investigator of a project that the National Science Foundation recently awarded to IHMC. Peter and his colleagues will be working on improving epidemiological models that will be able to more accurately forecast the rate of infections and deaths related to COVID-19. Show notes: [00:02:42] Dawn opens the interview by quizzing Peter about how he took up surfing at the age of 40. [00:05:48] Ken mentions that Peter grew up in Canada, but that his father, who is Italian, decided to move the family to Italy when Peter was 8 years old. Peter discusses what that was like. [00:08:37] Dawn mentions that Peter liked to go camping and canoeing as a kid, and developed a love for astronomy. Dawn asks if it is true that Peter used to keep NASA scrapbooks. [00:10:52] Peter tells the story of the role his mother played in his decision to go to Trent University in Ontario. [00:12:45] Dawn asks why Peter decided to major in psychology and anthropology despite his childhood fascination with astronomy. [00:14:47] Dawn asks what attracted Peter to Pittsburg and Carnegie Mellon University for graduate school. [00:16:12] Ken mentions that at Carnegie Mellon, Peter had the opportunity to meet and work with Herb Simon and Alan Newell, who back in the 1950s were the early pioneers of artificial intelligence. They won the Turing Award in 1975 for their contributions to artificial intelligence and the psychology of human cognition. Ken goes on to mention that Simon also won the Nobel Prize in Economics in 1978.  Ken asks how Peter, with a background in psychology and anthropology, got to work with these pioneers of the field of AI. [00:17:59] Ken mentions that one of his favorite works from Simon and Newell was their physical symbols concept and the papers that arose from that. [00:19:54] Ken mentions that Simon and Newell were interested in developing computational models that could mimic and simulate what the human mind was doing. In addition to AI, they also conducted research that looked at information processing, decision-making, problem-solving, organization theory and complex systems. Ken asks Peter how working with these pioneers influence his later research and career. [00:22:57] Ken asks Peter to elaborate on the concept that Simon introduced known as “satisficing.” It’s a concept credited with revolutionizing economics by introducing the idea of “bounded rationality” where people have limited time and resources with which to gather data to draw their conclusions, as opposed to the “rational man” concept which assumes that a person making a decision uses all conceivably relevant information to inform their decisions. [00:25:54] Dawn mentions that in Peter’s time at CMU, he became interested in building artificial intelligence systems to tutor people one on one.

Our guest today is Dr. Tim Broderick, the chief science officer here at IHMC. Tim is a surgeon and biomedical scientist who joined IHMC last year. Tim has had a fascinating career as a researcher, surgeon and aquanaut. He is well-known as a pioneer in laparoscopic, robotic and telerobotic surgery. He also has led multiple ground, flight and undersea-based biomedical research projects. As a result, he is an honorary NASA flight surgeon and a NOAA undersea saturation diver. Tim spent four years as a DARPA program manager where he conceived and established five high-impact biotechnology projects that included revolutionary programs focused on precision diagnosis and treatment of military-relevant diseases and injuries. Over the years, he  has developed a substantial portfolio of cutting-edge Department of Defense research. In today’s interview, Tim gives an  overview of a fascinating project, called Peerless Operator Biologic Aptitude, which he and his colleagues at IHMC are currently working on. Show notes: [00:03:09] Dawn opens the interview asking Tim about growing up in in Cincinnati and going to Cincinnati Reds games in the 1970s with his family. [00:04:59] Ken asks if growing up in the Apollo era and witnessing the moon landing as a child influenced his interest in science and space. [00:06:16] Tim recounts a story about his father saving someone’s life at church when Tim was a child and how that had a profound impact on him. [00:07:13] Tim tells another story from his college days when he saved a man who nearly had his arm chopped off by a machete. [00:11:22] Dawn asks if it is true that as a teenager Tim would regularly dress up as Scooby-Doo. {00:13:39] Dawn asks if Tim always knew he wanted to be a doctor since he grew up in a family full of doctors. [00:15:21] Ken asks why Tim decided to attend Xavier University in Cincinnati. [00:16:41] Dawn mentions that she has rarely heard of someone heading off to college with the idea of double majoring in chemistry and computer science, and asks how that came about. [00:21:17] Dawn mentions that Tim graduated in four years and in 1986 decided to stay in town for medical school at the University of Cincinnati College of Medicine. Dawn asks what drew him there. [00:22:58] Ken asks if Tim knew he wanted to become a surgeon when he started med school. [00:26:37] Dawn asks what lead Tim to go to Richmond, Virginia, for his residency as a surgical resident at the Medical College of Virginia. [00:28:23] Dawn asks about how Tim’s interest in minimally invasive surgery during his residency, which led to him becoming the director of surgical research at VCU’s Minimally Invasive Surgery Center. [00:29:32] Ken mentions that while Tim was working at VCU he became a consulting surgeon for telemedicine and robotics for the NASA Medical Informatics Technology Applications Consortium. Ken asks what that work entailed. [00:32:32] Ken asks about Tim’s early work in laparoscopic robotic and telerobotic surgery. [00:38:00] Ken asks about how Tim’s experience in remote surgery for astronauts led him to become an aquanaut and a crew member for NASA’s NEEMO 9. [00:40:24] Dawn mentions that it was Tim’s support that was one of the reasons that Dawn had the chance to join NEEMO as a crew member. She goes on to mention that Tim logged time underwater as a NEEMO aquanaut when he returned to the project several years after NEEMO 9 for NEEMO 12. Tim describes what his research was focused on for that mission. [00:43:33] Dawn notes the similarities between an operational environment such as NEEMO, spaceflight and the operating room. Dawn asks if Tim’s experiences in the operating room crossed over into his work on the NEEMO mission. [00:45:08] Tim shares some of his favorite memories from his time underwater with NEEMO. [00:49:48] Dawn mentions that beginning in the year 2003, Tim spent seven years as a senior scientist and trauma portfol...

Today we have the second of our two-part interview with Dr. Tommy Wood. Ken and Dawn talk to Tommy about his ongoing research into lifestyle approaches that can improve people’s health span, lifespan and physical performance. Tommy also talks about the physiological and metabolic responses to brain injury and how these injuries can have long-term effects on brain health. In part one of our interview, episode 110, Tommy shared his thoughts on the research he has done on the importance of metabolic health as a way to for people to protect themselves from COVID-19. Tommy also talked about his work on developing accessible methods to track human health and longevity and his research on ways to increase the resilience of developing brains. Tommy is a UK-trained physician who is also a colleague of ours here at IHMC. In addition to being a research assistant professor of pediatrics at the University of Washington  in the division of neonatology, Tommy occasionally spends time at IHMC as a visiting research assistant. For a more detailed explanation of Tommy’s background, check out the introduction to part one of our interview, episode 110. We also recommend checking out Tommy’s earlier appearances on STEM-Talk, episodes 47 and 48. Show notes: [00:02:50] Dawn continues our interview with Tommy asking why some people refer to Alzheimer’s as type-3 diabetes. [00:05:00] Dawn refers to a chart that Tommy incorporated into his IHMC lecture in February of this year, which was part of a paper that showed how glucose responds with age. Dawn asks Tommy to walk listeners through what the chart details. [00:06:38] Dawn asks if Tommy agrees with Art De Vany, who in his most recent appearance on STEM-Talk, said that insulin resistance is associated with nearly every major disease that people worry about today. [00:07:38] Tommy talks about the mean amplitude of glycemic excursions and how this is the best predictor of cognitive functions. [00:09:31] Dawn asks about the waffle/fast-food study, and what the results of that paper mean for the effect of the modern American diet on health and cognitive ability. [00:11:00] Dawn asks about the effects of stress on memory and mood. [00:13:39] Dawn posits that we see many a public-service announcement about the dangers of smoking and alcohol consumption, and asks if the case could be made that we should also have public service announcements about the dangers of high blood sugar, as it is even more of a public-health issue than smoking and alcohol consumption. [00:15:42] Tommy transitions to talking about the importance of sleep in regards to brain health. [00:17:01] Ken mentions that in response to the common advice of getting eight hours of sleep, Tommy has made the point that perhaps more important than the number of hours is the quality of those hours of sleep. [00:20:15] Dawn asks Tommy about the use of Tylenol PM, or Ambien before bed for those people who have difficulty getting to, or staying, asleep. [00:22:07] Ken asks if it is true that muscle mass and body composition are exceptionally important in regards to brain robusticity. [00:24:43] Ken asks about Tommy’s favorite paper, “1,026 Experimental Treatments in Acute Stroke,” and why he loves this paper so much. [00:27:31] Tommy gives an overview of what happens as a result of an acute brain injury across the lifespan. [00:29:35] Tommy discusses Creatine, which is a compound derived from amino acids that has been shown to be effective in treating brain injuries. [00:32:56] Dawn asks Tommy what he has learned in terms of the overall therapeutic effects of ketones. [00:40:20] Dawn asks what would be one question that Tommy wishes health experts contemplated more often, in terms of health span, and what would be his answer to said question. [00:42:35] Dawn mentions that Tommy has done a lot of work helping individuals overcome chronic health conditions,

Dr Jim Stray-Gundersen MD is Board Certified in General Surgery and a world-renowned expert in sports medicine, exercise physiology and training for sports performance. He has worked for 35+ years with Olympic and professional athletes, including the US, Norwegian, German, and Canadian national teams, as well as with NASA, Special Forces, and all levels of the US Military. Jim currently serves as the sports science advisor for the US Ski and Snowboard Association (USSA) and is the founder of the SG Performance Medicine Center in Park City, Utah. On this podcast, Dr Stray-Gundersen defines the mechanisms and application of Blood Flow Restriction (BFR) training and its effect on overall health, performance, power, and strength. He explains how BFR can deliver muscle gains identical to traditional strength training but with less weight, reduced risk of injury and faster recovery, making it a viable training option for people of all ages and fitness levels. He discusses the safety of BFR and the potential of this technique to revolutionise training and rehabilitation, particularly at this time when many of us no longer have access to a gym. Train harder and safer than you were before the gym shut down! Head over to bstrong.training before Aug 31, 2020, and use the discount code Performbetter to save 20% on the BFR system we talk about in this interview. Here’s the outline of this interview with Jim Stray-Gundersen: [00:00:19] Olympic skier Todd Lodwick's 2014 injury and recovery. [00:11:09] How blood flow restriction (BFR) works. [00:18:58] STEM-talk podcast: Episode 34: Jim Stray-Gundersen explains how blood flow restriction training builds muscle and improves performance. [00:19:04] IHMC lecture: Jim Stray-Gundersen - Blood Flow Restriction Training: Anti-aging medicine for the busy baby boomer. [00:19:08] Increased fast-twitch muscle fibers with BFR training; Study: Yasuda, T., et al. "Muscle fiber cross-sectional area is increased after two weeks of twice daily KAATSU-resistance training." International Journal of KAATSU Training Research 1.2 (2005): 65-70. [00:22:50] Improvement in strength and muscle mass with walking and other low-load training; Meta-Analysis: Effects of Blood Flow Restriction Training on Muscular Strength and Hypertrophy in Older Individuals: A Systematic Review and Meta-Analysis. [00:23:35] Increases in VO2max with BFR; Meta-Analysis: Formiga, Magno F., et al. "Effect of Aerobic exercise training with and without blood flow restriction on aerobic capacity in healthy young adults: A systematic review with meta-analysis.” International Journal of Sports Physical Therapy 15.2 (2020): 175. [00:30:34] Safety of BFR; Study: Nakajima, T., et al. "Use and safety of KAATSU training: results of a national survey." International Journal of KAATSU Training Research 2.1 (2006): 5-13. [00:39:24] B Strong vs. Kaatsu. [00:40:50] Contraindications for BFR. [00:43:35] BFR for varicose veins. [00:46:49] How to train. [00:48:48] 9-minute workout. [00:51:23] Measuring progress. [00:56:24] BFR for elite athletes. [00:57:51] Increased growth hormone and benefits for bone health; Studies: 1. Takarada, Yudai, et al. "Rapid increase in plasma growth hormone after low-intensity resistance exercise with vascular occlusion." Journal of applied physiology 88.1 (2000): 61-65. 2. Sato, Y., and T. Abe. "KAATSU-walk training increases serum bone-specific alkaline phosphatase in young men." International Journal of KAATSU Training Research 1.2 (2005): 77-81. [00:59:10] Why haven't we heard of this? [01:02:00] B Strong; Instagram, Twitter, Facebook.

Dr. Tommy Wood is a UK-trained physician who is making his third appearance on STEM-Talk. Earlier this year before the COVID-19 outbreak, Tommy gave a well-attended lecture at IHMC about the latest research on building and preserving brain health across people’s lifespans. The lecture was so popular we invited Tommy to join us for another STEM-Talk interview. Tommy is a research assistant professor of pediatrics in the University of Washington Division of Neonatology. He was our guest on episodes 47 and 48 of STEM-Talk. Tommy received his undergraduate degree in biochemistry from the University of Cambridge and a medical degree from the University of Oxford. In addition to working with newborn infants who have brain injuries, Tommy also develops performance optimization strategies for athletes such as Formula 1 racecar drivers and Olympians. As in our first STEM-Talk interview with Tommy, our conversation was so long and wide-ranging that we have divided it into two parts. In today’s episode, we talk to Tommy about the importance of metabolic health, especially as a way to protect ourselves from COVID-19. We touch on Tommy’s work at developing accessible methods to track human health and longevity, and also his research an assistant professor of pediatrics at the University of Washington where he studies ways to increase the resilience of developing brains. In part two of our interview, we talk to Tommy about his continuing research into lifestyle approaches to improve health span and lifespan and physical performance. We also have a fascinating discussion about the physiological and metabolic responses to brain injury and their long-term effects on brain health.  Show notes:  [00:05:15] Dawn asks about an article Tommy and a colleague recently wrote, in which Tommy points out that it is becoming increasingly clear that underlying conditions associated with suboptimal metabolic health appear to be associated with poor outcomes in patients with COVID-19. Considering the nature of these underlying conditions, such as obesity and hypertension, he argues that lifestyle-based approaches to protecting ourselves from COVID-19 are likely to be one of our best tools in addressing this ongoing pandemic as well as future pandemics. Tommy summarizes his key points from the article. [00:09:38] Dawn mentions that when Tommy was last interviewed on STEM-Talk, he had just become a senior fellow at the University of Washington and was in the process of moving permanently to the U.S. She goes on to mention that when she asked Tommy what brought him to the states, he said “a girl,” who he ended up marrying. The girl turned out to be Elizabeth Nance who was interviewed on episode 71 of STEM-Talk. Dawn asks how Elizabeth is doing. [00:10:51] Tommy gives an overview of his work as a research assistant professor of pediatrics at the University of Washington in the division of neonatology, where his focus is on ways to increase the resilience of developing brains and also ways to treat neonatal brain injuries. [00:12:45] Dawn explains that Tommy gives a disclaimer at the beginning of his talks that “many of my best ideas are stolen.” She asks what are his best sources for ideas. [00:14:42] Dawn mentions that when Elizabeth was on STEM-Talk, she mentioned that Tommy was constantly reading paper after paper, to the point that it is dizzying to look at Tommy’s computer screen. Tommy describes his research methods and how he goes about collecting material. [00:16:51] Ken mentions that Tommy’s current research interests include the physiological and metabolic responses to brain injury and their long-term effects on brain health. Ken asks about this as well as Tommy’s work to develop easily accessible methods to track human health, performance, and longevity. [00:18:59] Dawn asks why even as a neonatal neuroscientist, Tommy is still interested in working with football players, Formula 1 drivers,

Because of the number of questions that keep pouring in, today we have another Ask Me Anything episode.  We also have been receiving requests to do more of these shows, so we plan to record more frequent AMA episodes in the future. If you have questions for Ken and Dawn, email them to STEM-Talk producer Randy Hammer at rhammer@ihmc.us. In today’s episode we touch a little bit on COVID-19, but most questions revolve around diet and sleep and brain health. Ken also explains the meaning behind IHMC’s name and Dawn shares why she tweaked her vegetarian lifestyle to now include fish in her diet. Plus, Ken weighs in on the dangers of AI, real and imagined. It’s a fun, wide-ranging episode. Enjoy! Show notes: [00:02:28] Dawn opens the AMA with a listener question for Ken about his thoughts on social distancing. [00:03:19] A listener asks Dawn about the long-term pulmonary effects for survivors of COVID-19, and how this will impact divers. [00:04:49] Dawn reads a listener question for Ken about the U.S. relationship with China in regards to drug manufacturing: “During your interview with Katherine Eban, you made a comment about how current events related to COVID-19 truly highlight the fault in our dependency on Chinese manufacturing for our pharmaceuticals. That was just a few months ago…Where do you see our relationship with China heading with respect to drug manufacturing in the future?” {00:06:54] Ken talks about the need for each individual to take responsibility for the pharmaceuticals they ingest and recommends listening to Katherine’s Eban’s STEM-Talk interview and checking out her website, which has a wealth of information about generic drugs. [00:07:19] A listener asks Dawn about her shift from strict vegetarianism to occasionally adding fish into her diet. The listener wonders if this came about as a result of some of the discussions on STEM-Talk, or if her decision was inspired by something else? [00:09:07] A listener asks Ken if he uses branch chain amino acids, and if so how? [00:11:52] Ken talks about how combining essential amino-acid supplementation with mechanical loading via resistance training is a powerful strategy to combat the age-related loss of muscle function and mass that often leads to sarcopenia in the older population. [00:14:45] Dawn poses a listener’s question to Ken about why nutritionists seem to almost unanimously tolerate intermittent fasting or time-restricted eating, but oppose the ketogenic diet. The listener goes on to ask if there is any difference between getting into ketosis through diet versus fasting. [00:17:30] A listener asks Ken, who was an early adopter of a low-carb ketogenic diet, how his understanding of low-carb and healthy diets has changed as research has progressed. [00:19:25] A listener talks about how their adoption of time-restricted eating has led to late-night binge eating. The listener asks if it is true that skipping breakfast makes it harder to suppress ghrelin, sometimes referred to as “the hunger hormone.” The listener is curious about this because so many STEM-Talk guests talk about how they skip breakfast. [00:22:45] A listener asks Dawn: “In your podcast with Francisco Gonzalez-Lima, you talked about the potential role of methylene blue in protecting individuals exposed to environmental hypoxia. Do you know of any studies that have looked at this potential application of methylene blue?” [00:26:05] A listener asks Ken about adding legumes back into one’s diet after losing weight through the ketogenic diet, and if the weight will return if legumes are reintroduced. [00:29:20] A listener asks how Ken came up with the name “Institute for Human and Machine Cognition,” and what all the name entails? [00:30:51] A listener asks Dawn about the replication of extreme environments in a lab setting when studying human performance in various extreme environments. [00:34:56] A listener asks Ken: “There was some recent news cov...

Joining today: William Howell, Senior Creative and Multimedia Producer for the Institute for Human & Machine Cognition, and Mark Daniel, a research associate at IHMC and their exoskeleton pilotEarlier this year, I had a chance to meet with two remarkable people: IHMC’s Mark Daniel and Billy Howell. They’d just finished speaking at the Podfest Expo in Orlando, where they presented a machine—a part of the team’s collaborative research—that could help a man to his feet, that could give to his legs, to his knees that ability to, again, work.Having watched my own father struggle with such things after a brutal car accident, with where the one step should lead or how the body should turn, it was incredible to see and to hear how much we’ve learned in just a few short years. But the science here is only one half of the story: the other is a tale of friendship, compassion, and indomitable spirit. One that I don’t want to spoil too much of before you listen to it as I did, for the first time.Oh, and this episode was recorded live, so it might have the occasional quirk or surprise. -JTo learn more about IHMC, you can visit their site, subscribe to their video channel, or listen to their award-winning podcast, STEM Talk. You can also support their exoskeleton project or contact the team directly at: https://helpquix.org.You can follow our shows on Twitter @BrothersHerman and @jcertherealist.Like what you hear and want to show your support? Leave a review on your app of choice or subscribe for more on Patreon.com/herebetygers.Or contact us directly at Herebetygers.com, where we can help you find your tale and make it come to life.The Magician, written & performed by Immersive MusicKudos to Reckless Media for the final edits. Support the show (http://www.patreon.com/herebetygers)

Our guest today is Dr. Arthur De Vany, who we interviewed three years ago on episode 30 of STEM-Talk. Art, who is perhaps best known as one of the founders of the Paleo movement, is the author of “The New Evolution Diet: What Our Paleolithic Ancestors Can Teach Us About Weight Loss, Fitness and Aging.” Art is a professor emeritus of economics at the University of California, Irvine. In our first interview, we talked to Art about his early research into the economics of the movie business and how he created mathematical and statistical models to precisely describe the motion-picture market. In today’s interview, Art talks to us about the new book he’s working on that’s tentatively titled, “The Youthful Brain—A Revolutionary Program to protect the Brain, Extend Youthfulness and Prevent Alzheimer’s Disease.” The book is a continuation of Art’s ongoing study of the human body and brain and offers his strategies for preventing brain deterioration and maintaining a healthy, lean body. Show notes: [00:03:13] Dawn opens the interview mentioning that it has been three years since Art’s first appearance on the podcast. She asks Art what it is about the modern Western lifestyle that sends so many people to an early grave. [00:05:42] Dawn asks about Art’s discovery that the world’s healthiest, long-living individuals typically have low insulin. [00:07:44] Ken mentions that Art is working on a new book that will look at brain-body signaling and provide strategies for preventing brain deterioration and maintaining a healthy lean body. Art talks about how we originally planned to write about aging, but that most aging research is bull and that nobody really understands what it is. He explains that in his mind aging is basically a directed random walk into entropy. [00:10:11] Ken asks about one of Art’s key points, that Alzheimer’s disease and many other diseases of neural degeneration and cognitive decline are largely metabolic diseases compounded by loss of muscle mass and stem-cell exhaustion. [00:13:09] Dawn asks about the evolution of the human brain, and how the most recent additions to the brain are the most dependent on glucose metabolism. [00:14:22] Dawn mentions that synapses are essential to neuronal function, as they are the means by which neurons communicate signals. She asks Art to expand on the comment he made in his recent lecture at IHMC stating that “synapses are forever young but in ever need of support and protection.” [00:16:29] Ken asks about the lactate shuttle hypothesis, which is based on the observation that lactate is formed and utilized continuously in diverse cells under both anaerobic and aerobic conditions. [00:18:51] Dawn mentions the role of mitochondria, and how when they are not working the way they should that cells and tissues of our body become starved for energy, forcing us to rely on anaerobic metabolism. This results in a number of issues. She asks Art what we can do to maintain healthy mitochondria over our lifespan. [00:21:25] Art gives advice for reprograming the metabolism of the aging brain. [00:22:35] Ken asks about mTOR from an evolutionary perspective and why people have so many concerns regarding its role in cancer and degenerative disease. [00:24:35] Art explains his view of aging as the “failure of a renewal program,” and why aging is not programmed. [00:26:35] Dawn mentions that she has heard that Art eats just two meals a day, an early breakfast and dinner, to create a long interval between meals so his body can maintain low-insulin signaling. She asks how this brings on the defensive and repair pathways. [00:28:52] Ken asks about Art’s exercise routine and why he prefers fasted exercise. [00:30:46] Dawn asks about the importance of sleep, if Art still takes melatonin to help with his sleep, and what advice he has for people in terms of getting good sleep. [00:32:56] Dawn mentions that Art has commented that physically and genetic...

丽莎老师讲机器人之波士顿动力Atlas机器人完美自主导航欢迎收听丽莎老师讲机器人，想要孩子参加机器人竞赛、创意编程、创客竞赛的辅导，找丽莎老师！欢迎添加微信号：153 5359 2068，或搜索微信公众号：我最爱机器人。即使是能走会跑、甚至会做360度后空翻的波士顿动力Atlas机器人，也很容易摔倒。而且，它们走的每一步都是人类操作的。但美国人类与机器认知研究所 放出的一则视频显示，Atlas机器人已经能够在崎岖、狭窄的环境中自主导航了！大家对 Atlas 机器人一定不陌生。2013 年，波士顿动力公司为美国国防部高级研究计划局的一项挑战赛创造了 Atlas 机器人，它能走能跑，草地、雪地、碎石地都不在话下，甚至能做 360 度后空翻。它被称为 “逆天机器人 Atlas”。尽管有如此惊人的敏捷度，Atlas 机器人在走路时仍然很容易摔倒，尤其是当地面不平整时，双足机器人很难计算他们的脚应该放在哪里才能保持平衡。这是因为，Atlas 机器人走的每一步都必须由人类操作员决定，并通过用户界面输入。编程让机器人在平坦的地面上行走已经够困难的了，但是佛罗里达人类与机器认知研究所 (IHMC) 正在解决一个更大的挑战：确保双足机器人能够成功地在崎岖的地形上行走。该研究所自 2016 年以来一直在研究这个问题。IHMC 发布的最新视频，展示了这个领域的最新进展：机器人可以通过自主步伐规划算法，在狭窄的地形中自主导航了！IHMC 开发的自主步伐规划 程序正在波士顿动力公司的 Atlas 机器人和美国宇航局开发的 Valkyrie 机器人上运行。 视频展示了机器人在一堆煤渣块上面行走，甚至能穿过更窄的路径，由于导航选项有限，路径越窄导航就越困难。 操作人员为机器人指定一个开始点和一个结束点，然后映射所有可能的路径，评估每个路径的成本，选择一个最好的路径，最终到达目标点 —— 所有这些都发生在快速的现代硬件上。 利用 IHMC 的算法，这些机器人还可以快速适应环境变化和路径障碍，甚至能够在一条 “独木桥” 式的狭窄路径上行走。该算法使用机器人的传感器对环境进行调查，并将环境分割成多个部分。每个部分都被分解成一系列的多边形，从而创建一个环境模型，这样机器人就可以规划出从起点到目标点的每一步。 研究人员表示，还有很多工作要做 ——Atlas 机器人在狭窄小路上自主导航行走的成功率是 50%，在崎岖地形的成功率达到 90%，而在平坦地形的成功率接近 100%。研究人员计划提高路径规划的速度和能力，在迷宫和看不见的目标环境中测试，第一步是加入一个身体路径规划器。为了在一个杂乱或复杂的环境中行走，双足机器人必须要能够找出他们可以把脚放在哪个位置，而且需要快速完成这个过程。在参加 DARPA 机器人挑战赛时，IHMC 团队需要让人类操作员通过一个用户界面来指导 Atlas 的每一步放在什么位置，这个过程非常缓慢，给操作员带来了很大的负担。一旦脚步放错，机器人就会跌倒 在这个最新研究中，研究人员使用传感器获取机器人周围环境信息，生成点云，然后将点云分割成平面区域，以更紧凑的形式表示来自传感器的大量数据。 点云环境模型。有了这个环境模型，目标就变成了规划一系列的脚步，让机器人的初始点走到最终目标。 为此，研究人员使用基于图的搜索技术，如 A* 算法，图中的每个节点代表一个脚步。当展开一个节点时，对 x 和 y 平移进行网格搜索。在此基础上，考虑前一步的平移和旋转，并评估每一步的成本，确定下一步的最佳位置。 通过正确的调优和检查，这种方法适用于各种各样的环境。例如与平地上，它可以很快地规划目标，成功率接近完美。当穿越崎岖的地形时，规划速度也相当快。目标位置的改变会机器人避障的最佳路径。机器人还能够利用规划算法挤着穿过狭窄的通道。在这种环境下，为了避免与环境发生碰撞，机器人不得不几乎完全转向一侧。部分脚印在环境中提供额外的落脚位置，允许机器人在更复杂的地形中行走。机器人还可以重新规划路径。例如，当 的路径被阻挡时，它可以重新回到目标的新路径。最后一个例子是台阶高低不平的环境，目标地址是较高的平台。Atlas 能够规划它的路径先踩较高的煤渣块，然后回到较低的煤渣块，一高一低地走，直到到达目标。Atlas 机器人拥有了在平坦、粗糙和狭窄的路径上自主导航的能力，有望成为身手灵活、自主导航的灾区救援机器人，因为在灾区，倒塌的瓦砾使得传统的救援服务难以进入。

Our guest today is Francesca Rossi,  who for the past three years has been an AI Ethics Global Leader at IBM Research as well as an IBM Distinguished Research Staff Member. Prior to her time at IBM, she was a professor of computer science at the University of Padova, Italy. Francesca’s AI research interests include constraint reasoning, preferences, multi-agent systems, computational social choice, and collective decision making. Much of her research today is focused on the future of artificial intelligence and the ethical issues surrounding the development and behavior of AI systems. She is a fellow of both the worldwide association of AI (AAAI) and of the European Association of AI. She also has been president of the International Joint Conference on AI and the editor in chief of the Journal of AI Research. Sitting in for Dawn during today’s interview is IHMC colleague Brent Venable, who recently was named the inaugural director of a new Ph.D. program in Intelligent Systems and Robotics that is a partnership between IHMC and the University of West Florida. Brent is a graduate of the University of Padova and had Francesca as her academic advisor. Show notes: [00:03:25] Brent opens the interview asking Francesca where she grew up in Italy. [00:03:51] Brent mentions that Francesca was a curious child, who was fascinated with the moon landing. Brent asks what else Francesca was interested in as a child. [00:05:01] Francesca explains that if she were to stumble across a time machine she would be interested in going forward in time rather than backwards. [00:05:41] Ken asks why Francesca decided to study computer science in 1981when the field was relatively new. [00:07:22] Francesca discusses the one class in her academic career that stumped her, despite her good grades in every other subject. [00:08:36] Ken mentions that Francesca ended up in Austin, Texas after obtaining her degree in computer science, and asks what it was that lead her to the University of Texas and what research she did there. [00:11:40] Brent asks why Francesca decided to go back to Pisa after Texas to work on her Ph.D. [00:13:23] Brent mentions that after Francesca’s Ph.D., she moved to the University of Padova, where she worked for the next 20 years. Brent asks about the work that Francesca did in this period, particularly her seminal work on preferences for intelligent systems. [00:15:17] Ken discusses how Francesca became Brent’s academic advisor at Padova. Ken mentions that he has heard that the two of them had so much fun working together, that they did as much laughing as research during their time at Padova. He asks the two of them if that could possibly be true. [00:17:41] Francesca talks about the sabbatical she took to the Radcliff Institute. [00:22:00] Brent asks about an article in the Wall Street Journal that featured Francesca as well as a senior manager at IBM and one of the founders of Skype and how the article played a role in Francesca’s decision to move to the United States. [00:23:41] Francesca’s title at IBM is “Global Ethics Leader.” Brent asks Francesca to describe what the job entails. [00:30:00] Ken asks what Francesca envisions as the likely future of AI, and what she hopes for the future of AI. [00:31:54] Francesca discusses how we sometimes craft our visions for the future around our current technology, and that she believes that the proper approach should be to build our technologies around our visions for the future. [00:34:37] Brent asks Francesca for her thoughts on whether or not the fear of robots and AI going rogue and hurting people is a legitimate one, and what she thinks about the government adopting AI legislation. [00:38:23] Francesca gives her thoughts on the fears that AI will one day replace human workers. [00:41:43] Brent mentions that Matt Johnson, interviewed on episode 86 of STEM-Talk, had an article in AI magazine where he discussed human mach...

I HEART MY CHURCH: JUST ADD WATER When we stop drinking living water, we will thirst everything else. Discover what you're thirsting for and how you can bring living water to those around you with the last message in the IHMC series. To share what God has done in your life through Pathway Church, click here: https://mypathway.ccbchurch.com/goto/forms/121/responses/new