Podcasts about Jacques Monod

Sant Pau fue un hospital revolucionario. El arquitecto modernista Lluís Domènech i Montaner visualizó un recinto con múltiples pabellones conectados por zonas verdes, para que los pacientes pudieran recuperarse respirando y paseando en un oasis en medio de la ciudad. Estuve ingresado en Sant Pau de pequeño y, aunque mi dolencia no presentaba gravedad, estoy convencido que me recuperé mejor gracias a la belleza y al buen diseño de esos edificios. Hoy, después de la reforma, Sant Pau es un hospital moderno sin alma, en el que los pacientes se sienten mal tan solo entrar. Arturo Goicoechea entiende la medicina desde la óptica biológica: los organismos reaccionan al entorno. Antes como jefe de neurología y ahora desde GoiGroup, Arturo ayuda a sus pacientes a interpretar las señales que manda un cuerpo que es siempre sabio. Kapital es posible gracias a sus colaboradores: ⁠⁠lbo.legal⁠⁠. Asesoramiento jurídico para tu empresa⁠⁠ Víctor López Jr. fue un invitado especial en el podcast de Kapital. De todo lo que dijo, dos cosas que se me quedaron grabadas. Que no es necesario marcharse de Sevilla para hacer grandes cosas. Y que un abogado debe poder adaptarse a un entorno cambiante. Víctor lleva desde 2012 al frente de lbo.legal, una firma que ofrece servicios de asesoría jurídica, fiscal, laboral y de protección de datos, en un servicio diseñado para resolver todas las necesidades legales que puedas necesitar. Si estás buscando servicios jurídicos para tu empresa, ya sabes a quién llamar. Smartick⁠. El método online de matemáticas y lectura. ¿Quieres el mejor futuro para tus hijos? ¿Crees en la constancia y los buenos hábitos, en el desafío, en que existe un uso responsable de la tecnología? Si tienen entre 4 y 14 años, consigue que dominen los pilares de su educación, en el colegio y como personas: las matemáticas, la comprensión lectora, escribir bien, el pensamiento crítico. Smartick es el método online personalizado, basado en evidencias científicas, con solo 15 minutos al día por programa, que les ayudará a alcanzar su máximo potencial. Sin ayuda de los padres. Además, tendrás siempre disponible a expertos para consultar su evolución. Prueba 7 días gratis Smartick en este enlace y, si contratas, obtén un precio especial añadiendo el cupón KAPITAL. Patrocina Kapital. Toda la información en este link. Índice: 2:30 El dolor desde un punto de vista biológico. 13:04 Historias que construye el organismo. 20:28 Estupidez natural y estupidez artificial. 32:40 Tenemos la obligación de ser libres. 42:16 ¿Qué se siente siendo un murciélago? 49:11 Cotillear por maladaptación evolutiva. 55:12 El txikiteo como ritual diario. 59:44 ¿Existe el libre albedrío? 1:04:10 Futuros clientes de la medicina. 1:14:40 Padres carpinteros y padres jardineros. 1:21:34 Desactivar relatos perniciosos. 1:30:08 La newsletter de GoiGroup. 1:33:22 Mínimo una hora por visita. Apuntes: Tu cuerpo habla. Arturo Goicoechea. Sapiens, ma non troppo. Arturo Goicoechea. El dolor crónico no es para siempre. Arturo Goicoechea. Desaprender la migraña. Arturo Goicoechea & Inés Goicoechea. El origen de las especias. Charles Darwin. En movimiento. Oliver Sacks. Gratitud. Oliver Sacks. El mundo de ayer. Stefan Zweig. Los peligros de la moralidad. Pablo Malo. El miedo a la libertad. Erich Fromm. El azar y la necesidad. Jacques Monod. The painful truth. Monty Lyman. Relatos autobiográficos. Thomas Bernhard.

Avez-vous toujours votre doudou de quand vous étiez enfant ?L'association "Les P'tits doudous du Havre" offre aux enfants un doudou ou un jouet après leur opération chirurgicale. L'objectif de l'association : réduire l'anxiété des enfants et récompenser leur courage. Je me suis rendue à l'hôpital Jacques Monod pour rencontrer Dimitri, trésorier, et Céline, secrétaire de l'association "Les P'tits doudous du Havre". Merci à eux d'avoir pris le temps de répondre à mes questions. Site internet de l'association nationale "Les P'tits doudous"Site internet de l'association "Les P'tits doudous du Havre"

L'enquête d'Arsène Lupin, alias Raoul d'Avenac, se poursuit au manoir délabré de la Barre-y-va. Pour notre gentleman, il n'y a pas de doutes, les événements tragiques qui ont entouré le manoir de la Barre-y-va sont reliés par une seule et même cause : l'héritage de Monsieur Montessieu, le grand-père de la belle Catherine. Cette intuition semble encore plus probable lorsque le testament de l'ancien propriétaire du manoir est retrouvé... *** Fiction radiophonique diffusée dans l'émission “Les Aventures d'Arsène Lupin” de Maurice Renault - D'après une nouvelle de Maurice Leblanc - Réalisation : Abder Isker - Adaptation : Jean Marcillac - Première diffusion : 04/03/1961 sur France II Régionale de la RTF - Avec : Martine Sarceyn Tania Sourseva, Robert Marcy, Guy Tréjan, Lucien Nat, Jacques Mauclair, René Clermont, Geo Wallery, Jacques Monod et Michel Roux - Un podcast INA

Hugues de ThéCollège de France - Année 2023-2024Oncologie cellulaire et moléculaireColloque - Journée François Jacob : La vie sociale des microbes - Mechanics Guide Bacterial Surface Motility and Biofilm FormationIntervenant(s)Alexandre Persat, School of Life Sciences, EPFL, SwitzerlandLes Journées François JacobLes Journées François Jacob, organisées par l'Institut de Biologie du Collège de France, rassemblent chaque année les meilleurs spécialistes français et étrangers autour d'un thème à la pointe des enjeux de la recherche en biologie.Le lauréat du prix Antoine Lacassagne, attribué chaque année par le Collège de France à un chercheur en biologie, est traditionnellement invité à recevoir son prix lors des Journées François Jacob et à y donner un séminaire en relation avec ses travaux.Ces journées sont nommées en l'honneur de François Jacob, titulaire de la chaire Génétique cellulaire du Collège de France (1964-1991), prix Nobel de physiologie ou médecine 1965 avec André Lwoff et Jacques Monod pour la découverte de la régulation génétique de la synthèse des enzymes et des virus.

Hugues de ThéCollège de France - Année 2023-2024Oncologie cellulaire et moléculaireColloque - Journée François Jacob : La vie sociale des microbes - Microbial Ecosystems – Everything is Everywhere, but the Environment SelectsIntervenant(s)Nassos Typas, EMBL, Heidelberg, GermanyLes Journées François JacobLes Journées François Jacob, organisées par l'Institut de Biologie du Collège de France, rassemblent chaque année les meilleurs spécialistes français et étrangers autour d'un thème à la pointe des enjeux de la recherche en biologie.Le lauréat du prix Antoine Lacassagne, attribué chaque année par le Collège de France à un chercheur en biologie, est traditionnellement invité à recevoir son prix lors des Journées François Jacob et à y donner un séminaire en relation avec ses travaux.Ces journées sont nommées en l'honneur de François Jacob, titulaire de la chaire Génétique cellulaire du Collège de France (1964-1991), prix Nobel de physiologie ou médecine 1965 avec André Lwoff et Jacques Monod pour la découverte de la régulation génétique de la synthèse des enzymes et des virus.

Hugues de ThéCollège de France - Année 2023-2024Oncologie cellulaire et moléculaireColloque - Journée François Jacob : La vie sociale des microbes - Microbial Interactions in the Vaginal Environment: Revisiting the Normal and the PathologicalIntervenant(s)Samuel Alizon, Chercheur, Centre interdisciplinaire de recherche en biologie (CIRB - « Écologie et évolution de la santé ») – DR2 CNRSLes Journées François JacobLes Journées François Jacob, organisées par l'Institut de Biologie du Collège de France, rassemblent chaque année les meilleurs spécialistes français et étrangers autour d'un thème à la pointe des enjeux de la recherche en biologie.Le lauréat du prix Antoine Lacassagne, attribué chaque année par le Collège de France à un chercheur en biologie, est traditionnellement invité à recevoir son prix lors des Journées François Jacob et à y donner un séminaire en relation avec ses travaux.Ces journées sont nommées en l'honneur de François Jacob, titulaire de la chaire Génétique cellulaire du Collège de France (1964-1991), prix Nobel de physiologie ou médecine 1965 avec André Lwoff et Jacques Monod pour la découverte de la régulation génétique de la synthèse des enzymes et des virus.

Hugues de ThéCollège de France - Année 2023-2024Oncologie cellulaire et moléculaireColloque - Journée François Jacob : La vie sociale des microbes - The Ecology and Evolution of E. Coli VirulenceIntervenant(s)François Blanquart, Chercheur, Centre interdisciplinaire de recherche en biologie (CIRB - «Épidémiologie évolutive des maladies infectieuses») – CRCN, CNRSLes Journées François JacobLes Journées François Jacob, organisées par l'Institut de Biologie du Collège de France, rassemblent chaque année les meilleurs spécialistes français et étrangers autour d'un thème à la pointe des enjeux de la recherche en biologie.Le lauréat du prix Antoine Lacassagne, attribué chaque année par le Collège de France à un chercheur en biologie, est traditionnellement invité à recevoir son prix lors des Journées François Jacob et à y donner un séminaire en relation avec ses travaux.Ces journées sont nommées en l'honneur de François Jacob, titulaire de la chaire Génétique cellulaire du Collège de France (1964-1991), prix Nobel de physiologie ou médecine 1965 avec André Lwoff et Jacques Monod pour la découverte de la régulation génétique de la synthèse des enzymes et des virus.

Hugues de ThéCollège de France - Année 2023-2024Oncologie cellulaire et moléculaireColloque - Journée François Jacob : La vie sociale des microbes - Physical Properties of Single Cells and Social Behaviour in Dictyostelium DiscoideumIntervenant(s)Silvia De Monte, CNRS IBENS & Max Planck Institute for Evolutionary Biology, Plön, GermanyLes Journées François JacobLes Journées François Jacob, organisées par l'Institut de Biologie du Collège de France, rassemblent chaque année les meilleurs spécialistes français et étrangers autour d'un thème à la pointe des enjeux de la recherche en biologie.Le lauréat du prix Antoine Lacassagne, attribué chaque année par le Collège de France à un chercheur en biologie, est traditionnellement invité à recevoir son prix lors des Journées François Jacob et à y donner un séminaire en relation avec ses travaux.Ces journées sont nommées en l'honneur de François Jacob, titulaire de la chaire Génétique cellulaire du Collège de France (1964-1991), prix Nobel de physiologie ou médecine 1965 avec André Lwoff et Jacques Monod pour la découverte de la régulation génétique de la synthèse des enzymes et des virus.

Hugues de ThéCollège de France - Année 2023-2024Oncologie cellulaire et moléculaireColloque - Journée François Jacob : La vie sociale des microbes - How Intracellular Life Turns Symbiotic Bacteria into PathobiontsIntervenant(s)Olivier Espeli, Chercheur, Centre interdisciplinaire de recherche en biologie (CIRB - « Dynamique des chromosomes ») – DR1 CNRSLes Journées François JacobLes Journées François Jacob, organisées par l'Institut de Biologie du Collège de France, rassemblent chaque année les meilleurs spécialistes français et étrangers autour d'un thème à la pointe des enjeux de la recherche en biologie.Le lauréat du prix Antoine Lacassagne, attribué chaque année par le Collège de France à un chercheur en biologie, est traditionnellement invité à recevoir son prix lors des Journées François Jacob et à y donner un séminaire en relation avec ses travaux.Ces journées sont nommées en l'honneur de François Jacob, titulaire de la chaire Génétique cellulaire du Collège de France (1964-1991), prix Nobel de physiologie ou médecine 1965 avec André Lwoff et Jacques Monod pour la découverte de la régulation génétique de la synthèse des enzymes et des virus.

Hugues de ThéCollège de France - Année 2023-2024Oncologie cellulaire et moléculaireColloque - Journée François Jacob : La vie sociale des microbes - Mechanisms of Biofilm Community Assembly and FunctionsIntervenant(s)Knut Drescher, Biozentrum, University of Basel, SwitzerlandLes Journées François JacobLes Journées François Jacob, organisées par l'Institut de Biologie du Collège de France, rassemblent chaque année les meilleurs spécialistes français et étrangers autour d'un thème à la pointe des enjeux de la recherche en biologie.Le lauréat du prix Antoine Lacassagne, attribué chaque année par le Collège de France à un chercheur en biologie, est traditionnellement invité à recevoir son prix lors des Journées François Jacob et à y donner un séminaire en relation avec ses travaux.Ces journées sont nommées en l'honneur de François Jacob, titulaire de la chaire Génétique cellulaire du Collège de France (1964-1991), prix Nobel de physiologie ou médecine 1965 avec André Lwoff et Jacques Monod pour la découverte de la régulation génétique de la synthèse des enzymes et des virus.

Hugues de ThéCollège de France - Année 2023-2024Oncologie cellulaire et moléculaireColloque - Journée François Jacob : La vie sociale des microbes - Welcome, Seminar OpeningLes Journées François JacobLes Journées François Jacob, organisées par l'Institut de Biologie du Collège de France, rassemblent chaque année les meilleurs spécialistes français et étrangers autour d'un thème à la pointe des enjeux de la recherche en biologie.Le lauréat du prix Antoine Lacassagne, attribué chaque année par le Collège de France à un chercheur en biologie, est traditionnellement invité à recevoir son prix lors des Journées François Jacob et à y donner un séminaire en relation avec ses travaux.Ces journées sont nommées en l'honneur de François Jacob, titulaire de la chaire Génétique cellulaire du Collège de France (1964-1991), prix Nobel de physiologie ou médecine 1965 avec André Lwoff et Jacques Monod pour la découverte de la régulation génétique de la synthèse des enzymes et des virus.

Gerland aura bientôt sa fresque historique…. Le projet de fresque à Gerland est en marche, mais recherche encore des financements. "Les Compagnons des Pavillons", collectif d'habitants, travaille à la réalisation d'une œuvre de street-art. Cette dernière réunira les personnalités, les faits historiques et les savoir-faire Gerlandais. Cette œuvre murale sera réalisée au cœur du square Jacques Monod. L'association a lancé un crowdfunding pour financer l'opération. Pour en savoir plus, nous avons rencontré Amélie Remise, présidente des Compagnons des Pavillons... Ecoutez le podcast Pour effectuer un don et ainsi participer à la réalisation de cette œuvre de street-art, rendez-vous sur le site Hello Asso en recherchant les "Compagnons des Pavillons". Une page dédiée à cette création est également sur le site www.lescompagnonsdespavillons.fr

Le richissime diamantaire sud-africain Rudolf Kesselbach est un homme méfiant. Il craint les envieux et vit dans un bunker au sein d'un palace. Ses doutes sont fondés puisque Lupin le force à collaborer avec lui à la recherche d'un certain Pierre Leduc, qui le mènerait vers un secret considérable. Le baron refuse, il est retrouvé mort le lendemain par la police. Tous les indices mènent à penser que Lupin est l'assassin. C'est sans compter la sagacité de Lenormand, chef de sureté. *** Fiction radiophonique diffusée dans l'émission “Les Aventures d'Arsène Lupin” de Maurice Renault - D'après "813 : La Double Vie d'Arsène Lupin", roman de Maurice Leblanc - Réalisation : Abder Isker - Adaptation : Jean Marcillac - Première diffusion : 10/06/1961 sur la Chaîne parisienne de la RTF - Avec : Michel Roux, Georges Hubert, Henry Djanik, Jacques Monod, Philippe Mareuil, Georges Atlas, Robert Marcy, Thép Jehannes, Yves Furet, Jean Péméja, Fernand Fabre, Clément Bairam, Nicolas Amato et Henri Saint Georges - Un podcast INA.

Il y a tout de même une femme qui aurait pu trouver des os suspects dans la cuisinière. Cette femme est celle qui se trouvait aux côtés de Landru lorsqu'il fut arrêté : Fernande Segret. Et pour certains, le fait qu'elle soit allée plusieurs fois à Gambais – et qu'elle en soit revenue – pose question. Artiste lyrique, elle a été la dernière maîtresse de Landru. Il semble qu'il l'ait véritablement aimée et n'ait jamais envisagé de la supprimer. Son témoignage fut un moment particulier du procès, révélant le modus operandi de l'accusé mais peut-être aussi sa part d'humanité. Pour l'avocat de la défense, maître Vincent de Moro-Giafferri, il aurait pu à lui seul déstabiliser l'issue du procès. Ecoutez l'intervention de ce témoin-clé de la défense au tribunal, une reconstitution réalisée à partir de la transcription des minutes du procès. *** Crédits archive *** Extrait de l'émission télévisée "En votre âme et conscience" de Jean Prat - RTF - 01/03/1957 - Avec : Liliane Maigne, Pierre Tabart, Jacques Monod. *** Crédits podcast *** Sélection des archives : Elsa Coupard, Florence Dartois - Textes : Florence Dartois - Restauration et mixage : Ian Debeerst, Quentin Geffroy - Enregistrement voix : Guillaume Solignat - Voix off : Xavier Lemarchand - Musique(s) avec l'aimable autorisation d'Universal Production Music France - Unité de production : Delphine Lambard - Cheffe de projet : Laetitia Fourmond - Accompagnement éditorial : Emmanuelle Fellous - Responsable éditoriale : Zoé Macheret - Production INA.

Les témoins se succèdent à la barre. Le doute plane sur l'audience mais Landru est bientôt confronté à la macabre découverte qu'ont faite les policiers en perquisitionnant sa maison de Gambais : des ossements et fragments calcinés dans les cendres. Des restes humains qu'on pense avoir été brûlés dans sa petite cuisinière. À la barre, le docteur Paul, expert scientifique de l'enquête, nous livre les conclusions de son analyse et confond plus que jamais Landru. Écoutez une reconstitution fidèle de son témoignage diffusée dans l'émission “En votre âme et conscience” en mars 1957. Le comédien Albert Médina interprète l'expert, Pierre Tabart, l'avocat de la défense, maître Vincent de Moro-Giafferri, et Jacques Monod, le président du tribunal. *** Crédits archive *** Extrait de l'émission télévisée "En votre âme et conscience" de Jean Prat - RTF - 01/03/1957. *** Crédits podcast *** Écriture : Elsa Coupard, Florence Dartois - Textes : Florence Dartois - Restauration et mixage : Ian Debeerst, Quentin Geffroy - Enregistrement voix : Guillaume Solignat - Voix off : Xavier Lemarchand - Musique(s) avec l'aimable autorisation d'Universal Production Music France - Unité de production : Delphine Lambard - Cheffe de projet : Laetitia Fourmond - Accompagnement éditorial : Emmanuelle Fellous - Responsable éditoriale : Zoé Macheret - Production INA.

Actualités Locales : - L'Ecole 42 reçoit une subvention de la Communauté Urbaine contre l'avis de l'opposition- Les élus ont voté l'augmentation des transports scolaires pour l'année 2023/2024- Les services blanchisserie et cardiologies de l'hopital Jacques Monod étaient en grève jeudi dernier- Jean-Louis Rousselin, maire d'Octeville-sur-mer, démissionne- 10 ans après la première, une nouvelle charte de la vie nocturne a été signée au HavreOn parle aussi compostage urbain et évolution humaine avec IsabelleBonne écoute !

On this ID the Future, philosopher of biology Paul Nelson further explores AlphaFold 2, a cutting edge computer program from Google's DeepMind designed to rapidly suss out important secrets in the realm of proteins, indispensable molecular biological workhorses that come in thousands of different shapes and sizes. Nelson enthuses about AlphaFold 2 but also explains why he is convinced that AlphaFold's creators have hit a series of immovable obstacles. The watchword here—orphans. Tune in to learn what these mischievous orphan proteins are about, and what they suggest for AlphaFold, evolution, and intelligent design. Source

durée : 00:30:25 - Les Nuits de France Culture - par : Albane Penaranda - Par Alain Bosquet - Avec Jacques Monod

Neste podcast: Clóvis de Barros Filho aborda o livro de Jacques Monod para falar sobre vida e consciência.

durée : 00:19:59 - Les Nuits de France Culture - L'émission "L'Humour du monde", proposait une adaptation avec Rosy Varte de la nouvelle "Conrad" écrite en 1870 par Mark Twain. Mélodrame, tragédie... sans doute à lire un résumé de la nouvelle Conrad ces qualificatifs nous sembleraient appropriés. Mais à la lecture du nom de l'auteur, un doute s'immisce : Mark Twain. Ecrivain mondialement célèbre pour ses romans mettant en scène Tom Sawyer et Huckleberry Finn, Mark Twain était également un grand humoriste. Adaptée et enregistrée en public à Bayonne, en 1968, pour l'émission L'Humour du monde, cette nouvelle écrite en 1870 est d'ailleurs considérée comme la seconde manifestation écrite de l'humour très personnel de Twain, après une première expérience Ô combien réussie avec La Célèbre Grenouille sauteuse du comté de Calaveras, publiée en 1867. Conrad dont le titre original est A medieval romance, (Une Romance médiévale) est l'histoire d'un jeune homme, Conrad, qui est en réalité une jeune femme. Son père a menti sur son sexe depuis sa naissance afin d'assurer à sa descendance l'héritage du trône du duc de Brandebourg, l'oncle de Conrad, qui n'a point d'héritier mâle. Humour et suspens sont au programme de cette histoire au rythme échevelé menée par Rosy Varte. Interprétation : Rosy Varte, Jacques Monod, Lyne Chardonnet, Caroline Clerc et Maurice Chevit. Par Mark Twain - Adaptation : Michel Arnaud Réalisation : Claude Dupont L'Humour du monde - Conrad (1ère diffusion : 17/08/1968) Indexation web : Documentation sonore de Radio France Archive Ina-Radio France

On today's ID the Future, philosopher of biology Paul Nelson discusses his chapter in a recent Harvest House anthology edited by host Casey Luskin, The Comprehensive Guide to Science and Faith. Nelson says the theory of universal common descent, a key component of modern evolutionary theory, has generated multiple predictions that have failed. The prediction he discusses here is that there would turn out to be a single universal genetic code, since that's what we should expect if all life on earth is descended from the last universal common ancestor (LUCA). Findings over the past three decades have  proven that prediction spectacularly wrong. How does the theory of universal common descent shrug off this contrary empirical finding? The trick for Read More › Source

E' San Valentino, e il nostro Grande Amore è l'approccio interdisciplinare e allora eccoci qui ad omaggiare Charles Darwin e a provare ad applicare l'Evoluzionismo nell'economia e nella finanza. Partiamo omaggiando "Il caso e la necessità" di Jacques Monod, una lettura essenziale per approcciare la biologia contemporanea, e andiamo ad esplorare la biosfera e gli ecosistemi, ricordando innanzitutto che il capolavoro di Darwin è intitolato "L'origine delle specie" e non "Le origini dalla specie" perché il darwinismo, la selezione, è speciazione come proliferazione di nuove specie, non un malinteso "ne resterà solo uno", che idee criminali come l'eugenetica hanno tentato di utilizzare per appropriarsi di uno dei più grandi geni dell'Umanità. Tra scimpanzé, cornacchie, gorilla e picchi, guardiamo insieme al comportamento "economico" di tutta la biosfera: degli animali, delle piante e persino dei fiumi web: http://www.PianoInclinato.it email: redazione@pianoinclinato.it Newsletter EPT: https://tinyletter.com/PianoInclinato Sigla iniziale "The circle game" - Buffy Sainte Marie; sigla di chiusura by K. MacLeod Lic.: http://creativecommons.org/licenses/by/4.0/

Is our existence, and that of the world, the result of pure chance?

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: An Alien God, published by by Eliezer Yudkowsky on the LessWrong. "A curious aspect of the theory of evolution," said Jacques Monod, "is that everybody thinks he understands it." A human being, looking at the natural world, sees a thousand times purpose. A rabbit's legs, built and articulated for running; a fox's jaws, built and articulated for tearing. But what you see is not exactly what is there... In the days before Darwin, the cause of all this apparent purposefulness was a very great puzzle unto science. The Goddists said "God did it", because you get 50 bonus points each time you use the word "God" in a sentence. Yet perhaps I'm being unfair. In the days before Darwin, it seemed like a much more reasonable hypothesis. Find a watch in the desert, said William Paley, and you can infer the existence of a watchmaker. But when you look at all the apparent purposefulness in Nature, rather than picking and choosing your examples, you start to notice things that don't fit the Judeo-Christian concept of one benevolent God. Foxes seem well-designed to catch rabbits. Rabbits seem well-designed to evade foxes. Was the Creator having trouble making up Its mind? When I design a toaster oven, I don't design one part that tries to get electricity to the coils and a second part that tries to prevent electricity from getting to the coils. It would be a waste of effort. Who designed the ecosystem, with its predators and prey, viruses and bacteria? Even the cactus plant, which you might think well-designed to provide water fruit to desert animals, is covered with inconvenient spines. The ecosystem would make much more sense if it wasn't designed by a unitary Who, but, rather, created by a horde of deities—say from the Hindu or Shinto religions. This handily explains both the ubiquitous purposefulnesses, and the ubiquitous conflicts: More than one deity acted, often at cross-purposes. The fox and rabbit were both designed, but by distinct competing deities. I wonder if anyone ever remarked on the seemingly excellent evidence thus provided for Hinduism over Christianity. Probably not. Similarly, the Judeo-Christian God is alleged to be benevolent—well, sort of. And yet much of nature's purposefulness seems downright cruel. Darwin suspected a non-standard Creator for studying Ichneumon wasps, whose paralyzing stings preserve its prey to be eaten alive by its larvae: "I cannot persuade myself," wrote Darwin, "that a beneficent and omnipotent God would have designedly created the Ichneumonidae with the express intention of their feeding within the living bodies of Caterpillars, or that a cat should play with mice." I wonder if any earlier thinker remarked on the excellent evidence thus provided for Manichaen religions over monotheistic ones. By now we all know the punchline: You just say "evolution". I worry that's how some people are absorbing the "scientific" explanation, as a magical purposefulness factory in Nature. I've previously discussed the case of Storm from the movie X-Men, who in one mutation gets the ability to throw lightning bolts. Why? Well, there's this thing called "evolution" that somehow pumps a lot of purposefulness into Nature, and the changes happen through "mutations". So if Storm gets a really large mutation, she can be redesigned to throw lightning bolts. Radioactivity is a popular super origin: radiation causes mutations, so more powerful radiation causes more powerful mutations. That's logic. But evolution doesn't allow just any kind of purposefulness to leak into Nature. That's what makes evolution a success as an empirical hypothesis. If evolutionary biology could explain a toaster oven, not just a tree, it would be worthless. There's a lot more to evolutionary theory than pointing at Nature and saying, "Now purpose is allowed," or "Evolution did it!" The...

Facciamo un po di "pubblicità progresso" al nuovo libro del prof. Odifreddi grazie alla puntata di Radio2 Social Club - andata in onda su Rai2 il 11/11/21. ########################### Questo libro racconta una serie di 36 episodi di storia della scienza, ciascuno dei quali mostra come lo studio di un particolare animale da parte di uno scienziato gli abbia permesso di scoprire un determinato aspetto della Natura, in generale, o dell'uomo, in particolare (meritando, molto spesso, un premio Nobel per la scoperta). La lezione generale che può essere imparata dalle specifiche storie raccontate è che anche dagli animali apparentemente più insignificanti si possono trarre insegnamenti significativi sull'uomo. Il genetista Jacques Monod ha condensato questa lezione nel motto: “ciò che vale per il batterio, vale per l'elefante”. Il titolo Sorella scimmia, fratello verme riformula lo stesso concetto in maniera più antropomorfa, alludendo alla nostra ascendenza genetica e alla nostra discendenza cadaverica: dal “discendiamo dalle scimmie” di Darwin al “noi siam vermi” di Dante. Nonostante le apparenze, il titolo non allude invece al Cantico delle creature di Francesco d'Assisi, che sorprendentemente non fa alcuna menzione degli animali: soltanto dei corpi celesti (Sole, Luna e stelle), dei quattro elementi (aria, acqua, terra e fuoco), dei vegetali (fiori e frutti) e dell'uomo. Il che contrasta con la leggenda che, forse proprio per rimediare a questo peccato di omissione, ci presenta invece il fraticello come un predicatore agli uccelli e un ammansitore di lupi. Niente di tutto ciò che Francesco chiamava fratello o sorella può comunque esserlo sensatamente, a partire dal Sole e dalla Luna. Lo sono invece, in sensi precisi e spesso inaspettati, tutti gli animali dei quali parla questo libro, attinti da quel vero Cantico delle creature che è la storia della biologia moderna. --- Send in a voice message: https://podcasters.spotify.com/pod/show/vito-rodolfo-albano7/message

Cosa sono le bolle finanziarie? Esistono o sono una spiegazione a posteriori? I mercati in questo momento sono in bolla? In questa ultima puntata della prima stagione di Economia per Tutti andiamo a scoprirlo. I libri menzionati: 'The adjustment of stock prices to new informations' di E. Fama, L. Fisher, M. Jensen, R. Roll 'Irrational Exuberance' di Robert Shiller href="https://amzn.to/3xB9nuO 'L'evoluzione creatrice' di Henri Bergson https://amzn.to/36rupQn 'Il caso e la necessità' di Jacques Monod https://amzn.to/3xzETJk 'I principi del successo' di Ray Dalio https://amzn.to/3hxtdS8 web: http://www.PianoInclinato.it Newsletter di Economia per tutti: https://tinyletter.com/PianoInclinato email: redazione@pianoinclinato.it Sottofondo musicale composto da: Enrico Marani Sigla: Sweeter Vermouth by Kevin MacLeod https://incompetech.filmmusic.io/song... License: http://creativecommons.org/licenses/b...

Actualités Locales :- Mobilisation pour le personnel soignant devant l'hopital Jacques Monod hier- Création d'une mini-entreprise au collège André Gide- Ouverture d'un magasin de donuts au Havre- Le poste de secours de Sainte-Adresse converti en gite- Gérard et Manu Lanvin au Havre pour enregistrer une session liveLucie nous fera découvrir l'artiste havraise Blue PeonyBonne écoute !

Tiré de l'épisode de StoryRH "C'est quoi l'engagement?" https://storyrh.fr/2021/02/07/cest-quoi-lengagement/ Engagement = motivation + implication émotionnelle + durée C'est une espèce de surenchère par rapport à la motivation! Quels sont les piliers de l'engagement? De vieilles connaissances. 1) La finalité de l'activité, le fameux sens que les choses doivent avoir Pourquoi? Le sens, c'est la quête philosophique essentielle, c'est la pierre philosophale de la métaphysique. Jacques Monod, "Le hasard et la nécessité" « L'homme sait enfin qu'il est seul dans l'immensité indifférente de l'Univers d'où il a émergé par hasard. Non plus que son destin, son devoir n'est écrit nulle part. » Ce qui n'a pas de sens! Donc nous devons trouver un sens pour aligner nos énergies, savoir dans quelle direction la dépenser. C'est donc vrai pour nous et pour les groupes auxquels nous appartenons. Donc c'est vrai en entreprise: le sens a comme fonction de focaliser l'attention et les énergies. Donc donner du sens (et non recevoir du sens!) est source d'engagement: je suis d'accord de dépenser de l'énergie 2) L'autonomie dans l'activité, le fameux sentiment de contrôle, d'être "un agent actif dans la poursuite du but" (agency), d'être un lieu de contrôle (locus of control) Le lieu peut être interne ou externe: je contrôle ou pas le résultat (outcome) des évènements, "ce qui m'arrive" (Julian Rotter). Donc l'autonomie est liée à un lieu de contrôle interne: je contrôle ma destinée. Agent actif: notion liée à la self-efficacy d'Alberto Bandura, qui ajoute au contrôle la confiance dans la compétence en vue de réaliser une tâche. Donc l'autonomie, c'est quand je contrôle ce qui m'arrive et que j'ai les compétences nécessaires pour participer à l'effort commun: l'autonomie est source d'engagement parce qu'elle permet l'action, la dépense d'énergie. 3) La satisfaction liée à l'effort fourni, le fameux retour sur investissement La finalité et l'autonomie agissent sur la motivation et l'implication émotionnelle. La satisfaction agit sur la durée puisque c'est le mécanisme de feedback qui donne de l'information sur la dépense d'énergie. La satisfaction est source d'engagement parce qu'elle justifie (donne sens!) la dépense d'énergie. Et donc choix puisque cet engagement ne peut être que le résultat d'un choix. Sens donné = choix personnel Autonomie = sentiment personnel Satisfaction = sentiment personnel Il sera possible d'agir sur les conditions du choix, mais pas directement sur l'engagement, qui devient en quelque sorte un phénomène qui va émerger d'une série d'efforts consentis par l'entreprise. Le travail de l'entreprise, et en particulier celui de la direction et des RH, c'est de fournir aux collaborateurs les conditions de faire le choix de l'engagement pour l'entreprise. Nous sommes bien dans un phénomène complexe dans lequel il y aura corrélation entre les conditions fournies par l'entreprise et l'engagement des collaborateurs, mais c'est tout. Restons en contact, inscrivez-vous à notre newsletter! www.coapta.ch/newsletter Accès gratuit à toutes nos ressources: www.coapta.ch/campus Accès aux archives du podcast: www.coapta.ch/podcast Une production COAPTA, copyright 2020 COAPTA Sàrl Site internet: www.coapta.ch

Is our existence, and that of the world, the result of pure chance?

Tutto nel cosmo, incluso l'universo stesso, prima o poi finirà. La natura è totalmente indifferente alla nostra esistenza. La vita umana non ha un senso predeterminato. Queste riflessioni devono indurci allo sconforto? Secondo Telmo Pievani la risposta è no: questo libro è un meraviglioso tentativo di comprendere, con l'aiuto di Albert Camus e Jacques Monod, perché non bisogna cedere alla disperazione, ma anzi, come diceva un certo cantautore genovese, fare di tutto per consegnare alla morte una goccia di splendore, di umanità, di verità. TESTI CITATI 1) 'Finitudine' di Telmo Pievani: https://amzn.to/2M0IttK (versione ebook: https://amzn.to/2NzPEcs) 2) 'La fine è il mio inizio' di Tiziano Terzani: https://amzn.to/3b7WUVn (versione ebook: https://amzn.to/3dmrjlp) 3) 'Poesie' di Dylan Thomas: https://amzn.to/3jRzCqJ 4) 'Il mito di Sisifo' di Albert Camus: https://amzn.to/3rX1yfB (versione ebook: https://amzn.to/2LToahC SEGUICI E ASCOLTACI ANCHE SU: Instagram: https://www.instagram.com/i_cavernicoli/​ Facebook: https://www.facebook.com/ICavernicoli/​ YouTube: https://www.youtube.com/channel/UC0K7ULUh3sIb9z5FDcWblmg Spotify: https://open.spotify.com/show/2YFhi4C0SqcwEWrWdT4WEm Spreaker: https://www.spreaker.com/user/13221905​

Aujourd'hui, l'Abécéd'Air est un Abécéd'Autres en compagnie de la psychiatre Géraldine Delcambre et c'est le S de Soin qu'elle a choisi. Partie 1 - La crise et le collectif Née à Lesquin en 1979, Géraldine Delcambre est psychiatre de secteur, exerçant depuis toujours dans l'hôpital public. Après avoir travaillé pendant plusieurs années au centre Antonin Artaud animé par le Dr Patrick Chemla, elle a rejoint l'équipe du secteur d'Asnières-sur-Seine dirigé par le Dr Mathieu Bellahsen. Merci au fringant ami et comédien Jean-Baptiste Canivet extirpant Racine, Corneille, Hugo du petit matin, choyant Alejandra Pizarnik et Claude Ber, Et quelques pensées vives pour Ginette Garcin et Jacques Monod pour La Noiraude de Fournier et Gay.

Repost from October 2019. The history of genetics has a few famous partnerships - such as James Watson and Francis Crick or Francois Jacob and Jacques Monod. But there’s one pair without whom this podcast wouldn’t exist at all, and that’s Edith Rebecca Saunders and William Bateson, who founded The Genetics Society one hundred years ago. But while Bateson tends to get the glory, particularly for his popularisation of Gregor Mendel’s ideas about heredity, much less is heard about Saunders - the ‘mother of British plant genetics’. It’s time to tell her story.Full show notes, transcript, music credits and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzipGenetics Unzipped is written and presented by Kat Arney with audio production by Hannah Varrall. This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies in the world dedicated to supporting and promoting the research, teaching and application of genetics.

Retour sur l'entrevue de Darwin Brochero. JF, David et Fred discutent de l'entrevue et des thèmes abordés avec Darwin.1. «L'intelligence artificielle n'existe pas» (Luc Julia) . Vraiment? Pourquoi tant de malaise à se désigner comme «chercheur en IA» ? Pourquoi finance-t-on l'IA si personne n'en fait vraiment. Avant de nier l'existence d'une chose,  du moins avec une approche philosophique, il faut d'abord la définir.  2. Donner du sens au chaos .  Stochastique et probabilisme.. Contingence et nécessité.  «Hasard et la nécessité » (Jacques Monod). Les nouveaux modèles en IA permettent de faire le pont entre des phénomènes qui sont stochastiques (fruit du hasard) à petit échelle, mais qui sont régis par des paterns lorsqu'on les observe à grand échelle.  Nos modèles scientifiques classiques nous ont permis de mieux comprendre, mieux prévoir et de mieux prédire. Et les nouveaux modèles en IA permettent d'accroître encore davantage, en précision et puissance, ce pouvoir prédictif.  3. De l'éducation. De quelle éducation avons-nous besoin pour saisir, dans leurs intégralités, les problèmes éthiques et sociétaux associés à l'intelligence artificielle? Les universités sont-elles conçues pour résoudre de tels problèmes? Quoi faire pour s'assurer, que bien en amont, les enjeux éthiques et moraux soient mieux pensés par ceux et celles qui conçoivent les applications AI de demain?4. Croissance et décroissance (un nouvel hiver en IA?) .  Le champs de l'intelligence artificielle n'est pas né de la «dernière pluie». On se rappellera d'une grande vague d'enthousiasme envers l'IA dans les années 70 (financé par le DARPA aux USA), et que cette vague s'est estompée dans les années 80. On avait nommé «hiver» cette période de stagnation des travaux et du financement en IA. Or, le financement en IA ne cesse de croître. Si «l'hiver s'en vient», pour reprendre cette maxime des peuples du Nord (Game of Thrones), nous avons encore quelques belles saisons. Support the show

L'ospite di questo episodio è Telmo Pievani che è professore di Filosofia delle scienze biologiche all'Università degli Studi di Padova, divulgatore scientifico e direttore di Pikaia che è il portale italiano dell'evoluzione. Telmo Pievani è l'autore di “Finitudine. Un romanzo filosofico su fragilità e libertà” pubblicato da Raffaello Cortina Editore. La scienza ha svelato la finitudine di tutte le cose: dell'universo, della Terra, delle specie, di ognuno di noi. Come trovare un senso all'esistenza accettando la nostra finitezza? La risposta provano a darcela lo scrittore Albert Camus e lo scienziato Jacques Monod che coi loro dialoghi avvincenti e poetici, grazie all'autore, compongono le pagine di questo romanzo filosofico sulla fragilità e sulla libertà.Per saperne di più visita il sito:www.periscritto.itVuoi contattarmi? Scrivi a:marzia.tomasin@periscritto.it

Actualités Locales :> Un ouvrier décède sur un chantier à Saint-Vigor-d'Ymonville> L'auteur du braquage de la boulangerie, rue Irène Joliot Curie, s'est rendu à la police> La situation de plus en plus tendue à l'hopital Jacques Monod> Edouard Philippe était à l'école Valmy hier pour l'hommage rendu à Samuel Paty> Les Havrais du HAC Football peinent à trouver leur place dans cette D1William nous parlera du projet d'Agoraé de la FEDLHEt nous parlerons de la fin du service de streaming Google PlayBonne écoute !

Si descubrir al ARNm no fue suficiente Monod nos da cátedra sobre cómo opera la evolución. Es una fórmula sencilla: la necesidad surge del azar. SUMATE A NUESTRA CANTINA VIRTUAL, EN TELEGRAM: https://t.me/joinchat/P0hMQBWiS6MHjuumi3sHAg ¿Quieres invitarle una Cerveza al Epistemólogo Ebrio? 🍻 Bien, puedes colaborar con el podcast sin problemas📲 Te prometemos que tu donación servirá para aumentar la calidad de los episodios 🎙️, o de la cerveza 🍺, lo que esté al alcance de la epistemología😉. Desde ya, muchas gracias por el buen trago.😍 Puedes donar 20 desde el siguiente link: http://mpago.li/2iKKcVQ Puedes donar 50 desde el siguiente link: http://mpago.li/1AQEjC4 Puedes donar 100 desde el siguiente link: http://mpago.li/2RhFCqg Puedes escucharlo desde la aplicación SPOTIFY: https://open.spotify.com/show/1uobRUSrFJp52FZdcsCOQe?si=68RLeyXWQaW3FLQw8VNwGQ Puedes escucharlo directamente desde IVOOX: https://ar.ivoox.com/es/podcast-educacion-para-jovenes-epistemologia-audio_sq_f1638689_1.html Puedes escucharlo directamente desde YOUTUBE: https://www.youtube.com/channel/UCDaC646HXI5jCnkji4jBtMQ/featured?view_as=subscriber Puedes escucharlo directametne desde Google Podcast: https://podcasts.google.com/?feed=aHR0cHM6Ly93d3cuaXZvb3guY29tL2VkdWNhY2lvbi1wYXJhLWpvdmVuZXMtZXBpc3RlbW9sb2dpYS1hdWRpb19mZ19mMTYzODY4OV9maWx0cm9fMS54bWw&ep=14 Puedes escucharlo directamente desde APPLEPODCAST: https://podcasts.apple.com/au/podcast/educaci%C3%B3n-para-j%C3%B3venes-epistemolog%C3%ADa-por-audio/id1448671719 Puedes escucharlo directamente desde DEEZER: https://www.deezer.com/uk/show/748972 Puedes escucharlo directamente desde CASTBOX: https://castbox.fm/channel/Epistem%C3%B3logo-Ebrio-id1929217?country=us Tenemos Facebook: https://www.facebook.com/epistemologoebrio Tenemos Instagram: https://www.instagram.com/epistemologoebrio/ Tenemos Twitter: https://twitter.com/paravano69 ¡Siempre puedes compartirlo o a tu peor enemigo o a tu mejor amigo! SALUD Y BUENAS CIENCIAS Música: “Cantata de la Planificación Familiar” de Les Luthiers (Sonamos, pese a todo, 1971).

Hoy, segundo programa dedicado al año 1970. Cine, música, libros, acontecimientos destacados... El último hombre vivo, El pequeño salvaje, Investigación sobre un ciudadano por encima de toda sospecha, Domicilio conyugal, Tristana... Country Joe & The Fish, Deep Purple, Hank Marvin, Los Módulos, Cactus, Wallace Collection, Pedro Ruy Blas, Soft Machine... El informe de Brodie de Jorge Luis Borges, El azar y la necesidad de Jacques Monod, la enciclopedia Espasa habla sobre los carteristas y otros malhechores... Escuchar audio

Actualités Locales : - Rassemblement devant l'hopital Jacques Monod en soutien au personnel hospitaliers- 1270 élèves ont repris le chemin de l'école au Havre- la CGT de Renault Sandouville répond aux accusations- L'enseigne Primark n'a pas réouvert aux Docks Vauban- Le MuMa propose des visites virtuellesActualités Nationales : - L'exécutif donne son feu vert pour l'installation des conseils municipauxActualités Culturelles : - Betty Wright, égérie de la soul et du girl power, est décédée à l'age de 66 ans

durée : 00:28:24 - Carbone 14, le magazine de l'archéologie - par : Vincent Charpentier - L’anthropologie biologique vit actuellement des moments extraordinaires, de ces moments où tout est possible… L’Homme de Denisova, son émergence, son passé, ce que nous lui devons, est au cœur du magazine d’archéologie de France Culture. - réalisation : Vanessa Nadjar - invités : Eva-Maria Geigl directrice de recherche au CNRS et co-responsable d’une équipe en paléogénomique à l’institut Jacques Monod à Paris; Isabelle Crèvecoeur Chargée de recherche au CNRS (laboratoire Pacea, Bordeaux)

Dans la chronique, on parle de personnalités animales: girafe ambassadrice, ours militaire et tylacine disparu sont au programme !J'ai ensuite la chance de recevoir à mon micro un duo d'invités: Patrick Baud, auteur, veilleur, curieux professionel et fondateur de la chaine vidéo Axolot et Pierre Kerner, maitre de conférence en génétique évolutive du développement à l’université Paris Diderot et à l’institut Jacques Monod, mais également, vulgarisateur, blogueur, podcasteur et écrivain; Ils viennent nous parler des merveilles insolites du vivant, et de bestioles admirablement bizarres, compilées dans leur ouvrage "Nature secrète" paru aux éditions Dunod. On finit bien entendu, avec quelques conseils lecture. Bonne écoute ! Pour aller plus loin:Le livre "Nature secrète"Le site de Patrick BaudLa chaîne youtube Axolot de PatrickLe blog "Strange Stuff and Funky Things" de Pierre KernerLa série vidéo "Bestioles" sur youtube où Pierre apparaît aux côtés du Dr Nozman

durée : 00:28:34 - Carbone 14, le magazine de l'archéologie - par : Vincent Charpentier - L’anthropologie biologique vit actuellement des moments extraordinaires, de ces moments où tout est possible… L’Homme de Denisova, son émergence, son passé, ce que nous lui devons, est au cœur du magazine d’archéologie de France Culture. - réalisation : Vanessa Nadjar - invités : Eva-Maria Geigl directrice de recherche au CNRS et co-responsable d’une équipe en paléogénomique à l’institut Jacques Monod à Paris; Isabelle Crèvecoeur Chargée de recherche au CNRS (laboratoire Pacea, Bordeaux)

This week on Sinica, Kaiser speaks with Charles Bedford, who has been the managing director since 2012 of The Nature Conservancy (TNC)’s Asia-Pacific region, which encompasses Asia, the Pacific Islands, Indonesia, and Australia. The organization focuses on solving incredibly pressing and paramount issues central to the health of our planet. TNC is a charitable environmental organization that focuses on bringing the “best available science” to decision makers in all levels of government and local communities both inside and outside of the United States. In this episode, Kaiser and Charles discuss the formation of the national parks system in China beginning nearly two decades ago in which Charles and TNC played an instrumental role; the promising Chinese ecotourism industry; hydropower in China; “sponge cities” and “green bonds”; environmental activism and philanthropy; and local Chinese environmental organizations. What to listen for on this week’s Sinica Podcast: 12:30: Charles on responsibly developing hydropower projects in Southeast Asia: “The problem with the way that we have developed the world’s rivers is that we’ve done it through a death of a thousand cuts. In a sense that if you do these things bit by bit and without looking at entire river systems, then you can essentially destroy the ecological diversity, the function of the river for people, the ability of the river to produce food, to produce silts that are nutritional for agricultural production.” 25:50: Kaiser and Charles discuss sponge cities: “What China’s done over the last few years is taken a pretty remarkable step to rebuild its city infrastructure across the whole country. This is a massive, national ‘sponge city’ program to go back in and figure out how to de-hardscape and put in bioswales [drainage receptacles].”   31:21: Does China get too much credit or too much blame on the environmental front? “The preponderance, I’m told, of civil disturbances, riots essentially, in China, are resulting from pollution. [They] derive from some type of local pollution or land use problem with the government. So China is not necessarily a democratic place where issues can turf themselves up and go through a political process, but there’s still an outlet for people to say this is wrong. And the great thing about this is the Chinese government is pretty much open to these kinds of [environmental] protests.” 37:42: Charles tells Kaiser about an interview he had with Jack Ma, in which Ma describes nearly drowning in a river as a child in his native Hangzhou. He also shares that he returned there years later, and things had changed — he would have been hard-pressed to drown in that same river because the water now only reached his ankles, and he wouldn’t want to swim in it because it was clearly polluted. Ma is a Global Board Member of The Nature Conservancy. Recommendations: Charles: Brave Genius: A Scientist, a Philosopher, and Their Daring Adventures from the French Resistance to the Nobel Prize, by Sean C. Carroll, a book on World War II and the stories of Albert Camus and Jacques Monod. Kaiser: The Wizard and the Prophet, by Charles C. Mann, and a seven-part recording of a 1995 live show by the band Idiot Flesh. --- Check out the sponsor of this episode, Yoyo Chinese, by going to www.yoyochinese.com/sinica — be sure to enter the code Sinica at checkout to receive 15% off!

5 minutes pour aborder les plus grandes répliques du cinéma, c’est le retour estival de Ma ligne de chance, sur Radio Campus Paris. Nous découvrons aujourd’hui un célèbre film américain des années 90 : Forrest Gump. Le personnage éponyme de ce film de Robert Zemeckis nous interroge sur l'existence du hasard. https://www.youtube.com/watch?v=CJh59vZ8ccc « My momma always said life was like a box of chocolate : you never know what you’re gonna get ». « Maman disait toujours que la vie, c’était comme une boîte de chocolat : on ne sait jamais sur quoi on va tomber. » Cette réplique de Tom Hanks nous a donné à penser. Voici donc notre interprétation, subjective bien sûr, de cette trouvaille du scénariste Éric Roth. Forrest Gump, joué par Tom Hanks, a très tôt été diagnostiqué comme stupide, handicapé mentalement. Or sa vie, racontée par le film, deviendra, sinon des plus trépidantes, du moins des plus impressionnantes. En effet, il sera champion de football américain et champion de ping-pong. Mais il connaîtra également la guerre du Vietnam, durant laquelle il sauve quatre de ses camarades de la mort. Après avoir été capitaine d’une entreprise de crevettes, il entame un marathon long de trois années, qui inspire toute une génération. Ainsi, Forrest Gump semble avoir déjoué toutes les déterminations qui pesaient sur lui à la naissance. Reste que sa compréhension de la vie et de tout ce qui lui arrive, est très sommaire. Il utilise en général des phrases toutes faites, ou en tout faites par sa mère. Celles-ci expriment souvent en images ou en constructions simples des vérités de bon sens. C’est le cas de cette célèbre réplique située dans la scène d’ouverture du film. Comment la comprendre ? Sans que cela n'étonne plus l'auditeur assidu de Ma ligne de chance, la notion de hasard a une longue histoire derrière elle. Robert Zemeckis s'empare d'une idée aussi vieille que le monde, ou du moins que les philosophes. En particulier, la pensée d'Aristote peut nous permettre de mieux comprendre cette (si) célèbre phrase de Forrest. Pour cela, il faut expliquer la distinction aristotélicienne entre les différents types de causes, et notamment la cause finale. Que Forrest Gump mange des chocolats, c'est une chose. Qu'il les mange au hasard, c'en est une autre ; et c'est peut-être la clé de sa vie hors du commun. Venez découvrir pourquoi, dans le nouveau podcast de Ma ligne de chance !   Les références de l'émission:   Pour aller plus loin: Un philosophe qui pense que le hasard est le moteur du monde: le présocratique Démocrite. Une réflexion plus contemporaine sur la notion de hasard: Le hasard et la nécessité de Jacques Monod. Sur une possible introduction du hasard (entendu comme événement aléatoire) dans les arts, ici la littérature: Cent mille milliards de poèmes de Raymond Queneau.

Daniel Cohn-Bendit s'adresse à des étudiants, le 3 mai 1968 devant la Sorbonne à Paris. UPI/AFPMai 1968. La France est paralysée par la grève générale. Les étudiants se révoltent contre « la vieille Université ». Mais au fait, que se passe-t-il dans les laboratoires ? Michel Goldberg était alors jeune scientifique à l’Institut Pasteur dans l’équipe de Jacques Monod. Personnalité exceptionnelle, le Prix Nobel n’hésitait pas à se rendre sur les barricades, pour protéger les étudiants des foudres policières… Michel Goldberg ne travaille pas, ne conseille pas, ne possède pas de parts, ne reçoit pas de fonds d'une organisation qui pourrait tirer profit de cet article, et n'a déclaré aucune autre affiliation que son poste universitaire.

JACQUES MONOD raccontato da Telmo Pievani

Jacques Mandelbrojt est physicien a la retraite de l’Université de Aix Marseille mais a eu toute sa vie une d'artiste professionnel.   Il commence avec l’idée de Jacques Monod que son processus n’étais pas verbal mais visuel et musculaire, ou Monod disait qu'il arrivait a s'identifier avec une molécule. Il discuter son long parcours entre les arts et les sciences, dont la création d'un département d'art a l"université de Marseille, en tant que physicien dans les années 70. Il parlent des difficultés de mise en oeuvre d'enseignement art-science deja il y a 50 ans , rencontrant les mêmesobstacles qu'aujourd’hui. Discussion entre Jacques Mandelbrojt et Roger

Charissa Terranova talks to Sean B Carroll about overlaps in practices between humanists and scientists and his book Brave Genius, focusing on Albert Camus and Jacques Monod.

Charissa Terranova talks to Sean B. Carroll about overlaps in practices between humanists and scientists and his book Brave Genius, focusing on Albert Camus and Jacques Monod.

Molecular Aesthetics | Symposium Symposium at ZKM | Center for Art and Media, July 15 -17, 2011 in cooperation with DFG-Center for Functional Nanostructures (CFN) Karlsruhe Institute for Technology (KIT). Deleuze and Guattari's concept of the 'molecular' is not, as Eugene Thacker has recently remarked, necessarily about 'molecules' in a conventional scientific sense. Rather the concept is at the heart of a Deleuzian challenge to hierarchies of matter/form and molar/molecular. In A Thousand Plateaus the 'molecular' is synonymous with concepts of becoming, deterritorialisation and multiplicity. In practice, this means that Deleuze and Guattari challenge the genetic determinism that is often associated with molecular biology. When drawing on the work of Jacob and Monod, for example, they conceptualise the relationship between nucleic acids and proteins in terms of 'expression' and 'content'. The existence of what Deleuze and Guattari call a 'pure line of expression' (DNA) gives living organisms a high degree of deterritorialisation. This 'molecular' vision is developed most fully in Deleuze's work on aesthetics, and in particular his work on music, literature and film. In all of this work Deleuze adopts a radically materialist perspective. As far as music is concerned, he suggests that it might be possible to move away from thinking in terms of a musical 'matter' on which 'form' is imposed (this would in turn imply a hierarchy of matter, life, and spirit). In short, the coupling of 'matter-form' might be replaced by 'matter-force'. In this way, certain kinds of music would be able to render audible forces that would otherwise be non-audible. Similarly, as far as literature is concerned, Deleuze's molecular perspective highlights the ways in which writing is capable of rendering impersonal affects, percepts and singularities. In the case of film, Deleuze's reading of Bergson's materialism leads him to propose a radical immanence of the image in matter. /// Der Begriff des „Molekularen“ bei Gilles Deleuze und Pierre-Félix Guattari bezieht sich, wie Eugene Thacker jüngst angemerkt hat, nicht unbedingt auf „Moleküle“ im wissenschaftlichen Sinn. Vielmehr ist er die Spitze, die Deleuze gegen die Hierarchien von Materie/Form und Molar/Molekular wendet. „Molekular“ steht in Tausend Plateaus gleichbedeutend mit Werden, Deterritorialisierung, Multiplizität. Die beiden Autoren formulieren daraus eine Kampfansage an den genetischen Determinismus, der beharrlich mit der Molekularbiologie in Zusammenhang gebracht wird. In ihrer Behandlung des Werks von François Jacob und Jacques Monod interpretierten sie die Beziehung zwischen Nukleinsäuren und Proteinen unter dem Aspekt von „Ausdruck“ und „Inhalt“. Die Existenz dessen, was Deleuze und Guattari als „reine Linie des Ausdrucks“ (DNS) bezeichnen, verleiht dem lebenden Organismus einen hohen Grad an Deterritorialisierung. Am stärksten ausgeprägt ist der „molekulare“ Blick in Deleuzes Schriften zur Ästhetik, insbesondere in jenen zu Musik, Literatur und Film, in denen er eine radikal materialistische Position bezieht. In Bezug auf die Musik spekuliert er, dass es möglich sein müsse, von der Vorstellung einer musikalischen „Materie“, die in eine „Form“ gezwungen wird (und ihrerseits eine Hierarchie von Materie, Leben und Geist voraussetzt), abzugehen und die Dualität Materie-Form durch Materie-Kraft zu ersetzen. Bestimmte Arten der Musik könnten damit unhörbare Kräfte hörbar machen. In der Literatur erhellt der molekulare Blick, wie unpersönliche Affekte, Empfindungen und Singularitäten sich in Worte fassen lassen. Und in seiner Filmtheorie postuliert Deleuze ausgehend vom Materialismus Bergsons eine radikale Immanenz des Bilds in der Materie.

Patrimoine héréditaire, tests génétiques et médecine prédictive Patrick GAUDRAY Directeur de Recherche CNRS, Président des Conférences Jacques Monod, membre du Comité Consultatif National d'Éthique Les Lundis de la Connaissance - 12 octobre 2009 - Nice.

Fête de la science 2003

16 Oct 2006 19:00:00 GMT support-monupmc@upmc.fr

16 Oct 2006 19:00:00 GMT support-monupmc@upmc.fr

sermon transcript Introduction: Types and Fulfillment The Purpose of History What is the purpose of history? When I ask the question, I assume that there is a purpose. To some atheistic scientists, the very question itself is absurd — they would say there is no purpose to history. I read about Jacques Monod, who won the Nobel Prize in 1965 for discovering the replication mechanism of genetic material. In 1970, he branched out into philosophy and wrote a book called Chance and Necessity. Newsweek, writing at the time, described his argument in this way: “After some thirty years of research in biochemistry and genetics, the short trim scientist [Monod] is convinced man’s existence is due to the chance collision between miniscule particles of nucleic acid and proteins in the vast ‘pre-biotic soup.’ Indeed, Monod argues that all life results from the interaction of pure chance— unpredictable mutations—and necessity, or Darwinian selection.” That sounds like a book well worth reading, don’t you think? It reduces us to chance and necessity. Monod himself, in the book, wrote this: “Chance alone is at the source of every innovation, or all creation in the biosphere. Pure chance, absolutely free but blind, at the very root of the stupendous edifice of evolution: this central concept of modern biology is no longer one among other possible or even conceivable hypotheses. It is today the sole conceivable hypothesis…” [The only thing that explains our existence is chance and necessity.] “The universe was not pregnant with life nor the biosphere with man. Our number came up in a Monte Carlo game. It is any wonder if, like the person was has just made a million in the casino, we feel strange and a little unreal?” I find that argument strange and a little unreal. It certainly leaves us with nothingness as our future and nothingness as our present significance. It is ironic that some of the same atheistic scientists participate with SETI, or Search for Extraterrestrial Intelligence, listening to radio static from the cosmos, trying to string together proof of intelligent communication. They are looking for patterns, and if they see regular pulsing patterns, they say, “We knew all along that there is intelligence out there. There has to be because there is not just one Monte Carlo game, but lots of spinning wheels. Somewhere, elsewhere, the chance of life must have come up. We are waiting to hear and looking for patterns.” Patterns of the Future Gospel Instead of looking for patterns outside of our planet, I urge you to look for patterns in the Old Testament. In doing so, I find the cross of Jesus Christ again and again, and it is not at all accidental. There are amazing patterns in Biblical history and each one contributes to some degree to our understanding of the Gospel. Noah built an Ark. On it, there was safety; off it, there was destruction. In Christ, you live. Outside of Christ, you perish. Joseph’s jealous brothers sold him as a slave; he was despised and rejected by his own brothers, and yet he ended up becoming the very avenue of salvation for Jacob’s family. Judah, one of the very ones who had rejected him, later came to his senses and started to have some sympathetic love and compassion for his brother, Benjamin. He offered his life in exchange for Benjamin’s, to substitute himself. Judah, the ancestor of Christ, did this. It is no accident. There is no chance in this. History is a story — an elaborate tapestry woven together, all of which points again and again to the cross. The Passover at the time of the Exodus, when the Israelites were coming out of Egypt, liberated from slavery and bondage and brought over into the Promised Land, is just such a picture as a whole of salvation. But it came at a price. The Passover lamb had to be sacrificed; its blood had to be poured out; it had to be applied. Those under the blood escaped, survived, though they deserved death. But the animal was sacrificed in their place so that they could live. See the patterns, again and again, pointing to Christ? Old Testament scripture points prophetically to Christ. There are two different kinds of prophetic passages in the Scriptures. One is verbally predictive prophecy such as Isaiah 53:6-7: “We all, like sheep, have gone astray, each of us has turned to our own way; and the Lord has laid on him the iniquity of us all. He was oppressed and afflicted, yet he did not open his mouth; He was led like a sheep to the slaughter and as a lamb before her shearers is silent, so he did not open his mouth.” Or Isaiah 9:6: “For to us a child is born, to us a son is given, and the government will be on his shoulders. And he will be called Wonderful Counselor, Mighty God, Everlasting Father, Prince of Peace.” Verbally predictive prophecy tells us something of the Christ who would save our souls. The other category, typical, or type, prophecy, shows the depth and the richness of God’s communication to the human race by His sovereign control of history. This means that Biblical history means something. It points to the cross. Hebrews 11:19 says, “[Abraham] considered that God is able to raise people even from the dead, from which he also received [Isaac] back as a type.” The idea is that Isaac was a type or a pattern of something that would come later, namely Christ. There are numerous types or pictures. Something is acted out in history and captures an element of Christ’s salvation work. Of all the types that we have in the Old Testament, none is better and clearer than what happened on Mount Moriah in Genesis 22. It is the pinnacle, the peak, of typical predictive prophecy. The purpose of history is that God may be glorified in the redemption, the full salvation of sinners from every tribe and language and people and nation, who will be clustered around the throne, worshiping Him forever and ever. We get the joy, He gets the glory. The purpose of Old Testament biblical history is to point, in verbal and predictive prophecy, to the Christ who will accomplish that great salvation. Context What is the context? I was taught in seminary that we must not take verses out of context. You can make the Bible say anything you want if you rip things out of context. In order to emblazon it in our minds, they gave us a slogan, “Context is king.” The Old Testament is the king of context. Genesis 22 sets the context of waiting for the Christ. When he came, he fulfilled not just this type, but every type in the Old Testament. Galatians 4 says that in the fullness of time, Christ came. After God had set the table, then the feast came and the feast was Christ. The immediate context is that Abraham, a man who lived 2000 years before Christ, was called to leave his country and his people and go to the land that God would show him. God made a promise. He said in Genesis 12:2-3, “I will make you into a great nation and I will bless you; I will make your name great, and you will be a blessing. I will bless those who bless you, and whoever curses you I will curse; and all peoples on earth will be blessed through you.” What an incredible promise. Eventually, that promise focused on one miracle baby named Isaac. God promised in Genesis 17:19, “…your wife Sarah will bear you a son, and you will call him Isaac. I will establish my covenant with him as an everlasting covenant for his descendants after him.” Abraham waited for 25 years after the original call had come and finally at age 100, after 25 years of waiting for that promise, Isaac was born. What a moment of joy and celebration, as God at last fulfilled his prediction and His promise. One day, a shocking command came from God. The same God who had both predicted and provided Isaac now commanded, “Take your son, your only son, Isaac, whom you love, and go to the region of Moriah. Sacrifice him there as a burnt offering on one of the mountains I will tell you about.” This story makes up the greatest typical predictive prophecy in the Old Testament. It is a picture of the sacrifice of Jesus Christ. I have identified 15 points of contact between the story of Abraham and Isaac and the Gospel of Jesus Christ. We have looked at Genesis 22 from the human side: how difficult it would have been for Abraham to obey the command; how Abraham is our father, laying down footsteps of faith so that we should follow them; the nature of his faith; the nature of testing of faith, which comes to all of us. This was given from the human perspective, Abraham looking upward, so that we become his followers, walking in his footsteps. Now we will take it from God’s perspective, looking to see what He is communicating about the Gospel. Types Listed and Fulfilled The “Father-Son” Relationship The first type or point of contact between the Abraham and Isaac story and the Gospel is the father-son relationship. God said, “Take your son, your only son, Isaac, whom you love, and sacrifice him.” Human relationships, whatever they may be, are crafted in the image of God. We are created in His image. God came first, we came after. So all human relationships are patterned after the Trinitarian relationship. We believe, as Christians, that there is one God who has eternally existed in three persons: Father, Son and Holy Spirit. The relationship between an earthly father and son is patterned after the heavenly relationship between the Heavenly Father and His only begotten Son. We first learn the human relationship. We do not come into the world knowing or reading the Bible. We start as infants and we live and first experience parental love. Sons experience the love of a father. Those who do not experience it first hand see it in culture and at least know what a father and a son is like. We can all understand that relationship. That knowledge heightens for us a sense of the cost, a sense of the sacrifice, what it must have been like for Abraham to offer his son Isaac. As we look at the human side, we can see the cost of the sacrifice and the father-son relationship. Patrick Morley, in his book, The Man in the Mirror, tells a heart-wrenching story about a group of men and a 12-year-old boy who went fishing in Alaska. They used a pontoon airplane to reach a remote area of Alaska. They enjoyed a great day catching salmon, but then they noticed that the tide has gone out and that the plane was no longer in water. They had to wait for a while for the water to come back in so they could take off. And when the time came for them to take off, they did not know that one of the pontoons had sprung a leak and was half-filled with water. As they tried to take off, it crashed back down into the bay. All of them survived the crash but faced a vicious riptide in the cold Alaskan water. They began to swam hard for the shore, and two of the men made it with great difficulty, exhausted. It was all they could do to survive. As they looked for the other man and his son, they saw them far out in the water. The father was holding the son, waiting because the father knew the son could never make it on his own. The father was unable to bring the son in and chose to die with his son rather than to swim to shore without him. So they perished there. Charles Spurgeon told a similar story from the ancient world during the time of the Roman persecution. Two sons of a father were arrested for being Christians. The father, aged beyond the interest of the empire, escaped arrest. He went to intercede with the Roman guards and begged that his sons might be released that he might die in their place. They were moved with pity and decided to go as far as they could. They gave him a choice to exchange his life for one. Spurgeon says, “He looked first at one, and then at the other. He would fain say, ‘Spare that one,’ but then they would put the other to death; and he would fain say, ‘Spare this one,’ but then the other must die. And so the old man alternated between one and the other, undecided which should be released, till both were slain.” He could not give the word for either to be executed. The human level helps us to understand what it must have been like for the father to give up the son. Genesis 22:2 is the first use of the Hebrew ahava, the word for “love.” “Then God said, ‘Take your son, your only son, Isaac, whom you love, and go to the region of Moriah.’” When we think of love, we think first of male-female love. Most love songs are about that kind of love. As important as that is in God’s redemptive plan — God created a man and a woman and told them to be fruitful and multiply — this word is introduced first in a father-son context. Is that incidental? I do not think so. The whole universe is based on the love the Father has for his only begotten Son. It came first before any man and woman were created. The father loved the Son, and He has eternally loved him. Jesus prayed in John 17:24, “Father, I want those you have given me to be with me where I am, and to see my glory, the glory you have given me because you loved me before the creation of the world.” In effect, he says, “I want to bring these believers whom you have given me, into the love relationship that you and I have had before the foundation of the world.” It is no accident that the first time love appears in the Bible is this father-son love. It is no accident that the first instance of love in the New Testament is at Jesus’ baptism in Matthew 3:17: “…and behold, a voice from heaven said, ‘This is my beloved Son, with whom I am well pleased.’” It is the love of the heavenly Father for his only begotten son. It is the first time that love appears in Mark’s and Luke’s Gospels. The first time that love appears in John’s Gospel is John 3:16: “For God so loved the world, that He gave His only begotten Son, that whoever believes in Him shall not perish, but have eternal life.” Our salvation is being brought into the love relationship between the Father and the Son. That is how we get saved. God is able to love you as a sinner because He loves His Son on your behalf. He sees you in Christ, and so it is fulfilled. Romans 8:32 says, “He who did not spare his own Son, but gave him up for us all — how will he not also, along with him, graciously give us all things?” In the words of the Michael Card song “God Will Provide a Lamb”, “What Abraham was asked to do, he’s done. He’s offered his only son.” Predetermined, Deliberate Choice by the Father The second type is the pre-determined and deliberate choice on the part of the Father. Abraham knew exactly what he was doing. This was not a fit of passion that came over him in an instant, and then he did it. There are tasks of preparation involved. Verse 3 says, “Early the next morning Abraham got up and saddled his donkey. He took with him two of his servants and his son Isaac. When he had cut enough wood for the burnt offering, he set out for the place God had told him about.” He had to saddle his donkey and chop the wood. What must he have been thinking as he was doing those things? This was a predetermined deliberate choice on the part of the father to give up the son. What about the three-day journey? As he was walking along, he must have been constantly thinking, “My son will be sacrificed.” It was a predetermined, deliberate choice on the part of the father, fulfilled in Christ. Jesus was not caught or arrested or captured, but was given over by the Father to death, done by the predetermined choice and deliberate foreknowledge of God. Peter, preaching at Pentecost, said in Acts 2:23, “[Jesus of Nazareth] was handed over to you by God’s set purpose and foreknowledge; and you, with the help of wicked men, put him to death by nailing him to the cross.” Acts 4:27-28 says, as they were praying about the crucifixion, “…truly in this city there were gathered together against your holy servant Jesus, whom you anointed, both Herod and Pontius Pilate, along with the Gentiles and the peoples of Israel, to do whatever your hand and your plan had predestined to take place.” This was the deliberate predestination of God. Revelation says that Jesus is the Lamb slain from the foundation of the world. The heavenly Father did not have a small three-day walk but a 4000-year walk through history every moment thinking, knowing Jesus would die for all the sins of his people. When Noah got drunk, Jesus died for that. When Abraham sinned with Hagar, Jesus died for that. When David saw Bathsheba, committed adultery with her and had her husband killed to cover it up, Jesus died for that. God thinks about these things as they happen, and this was a predetermined choice on the part of God the Father. Father and Son Alone Third, the father and son were alone on Mount Moriah. The two servants were left behind. There were no other humans with them when this happened. Verse 5 says, “Then Abraham said to his young men, ‘Stay here with the donkey; I and the boy will go over there and worship and come again to you.’” Even dear Sarah is entirely left out of this story. Not that she was not important — she was, and that is why there is so much about her in prior events — but this is between the father and son as typical predictive prophecy. There was no one other than the father and the son. We must be clear about this. We Protestants, as we communicate with our dear Roman Catholic friends who bring in Mary as Co-Redemptrix, as though she had a role to play in redemption, must be careful. We have much common ground with Catholics, but that doctrine is not one of them. When Pope John Paul says that Mary’s intense sufferings united with those of her son were “also a contribution to the Redemption of us all”, you must say no, for the Father and the Son alone worked out this salvation. Your good works were not there; there was nothing of you there. It was the Father and the Son in a transaction between them. Salvation was worked at Calvary as an eternal transaction between the Father and his Son. Isaiah 59:16-17 says, “He saw that there was no one, he was appalled that there was no one to intervene; so his own arm worked salvation for him, and his own righteousness sustained him. He put on righteousness as his breastplate, and the helmet of salvation on his head; he put on the garments of vengeance and wrapped himself in zeal as in a cloak.” There was no one with them, and neither was there anyone at Calvary during the transaction of the salvation of your soul. It was a transaction between the Father and the Son alone. Carried His Own Wood Fourth, Isaac carried his own wood. Verse 6 says, “And Abraham took the wood of the burnt offering and laid it on Isaac his son.” We assume that Isaac was no small boy. It adds emotional weight to think of an innocent 5-year-old to be sacrificed, but I do not think that was the case. This was a strapping young man who was able to carry the wood for the burnt offering up the mountain. The Hebrew word for lad, or young man or boy, can range as high as 25 years old or older. This was a strong young man who carried his own wood. This was fulfilled literally, physically in Jesus. We could not get any more close connection here. John 19:16-18 says, “So they took Jesus, and he went out, bearing his own cross, to the place called the place of a skull, which in Aramaic is called Golgotha. There they crucified him…” The Greek in verse 17 is intensive. It literally says, “He, bearing his own cross himself, went out.” That is a point of contact back to Genesis 22 as we see Isaac going up the hill bearing his own wood himself. It was fulfilled physically in Christ, but even better, it is fulfilled spiritually. Isaiah 53:6 says, “All we like sheep have gone astray; we have turned every one to his own way; and the LORD has laid on him the iniquity of us all.” That is the real burden of Calvary, laying on Christ the crushing burden of all of your sin and mine and that of a countless multitude, redeemed from every tribe and language and people and nation. What an incredible burden Jesus carried to Golgotha. Charles Spurgeon wrote: “...the sin of the ages past and the sin of the ages to come, the sins of those of the elect Who were in heathendom, and those who were in Jewry; the sin of the young and the old, sin original and sin actual, all made to meet, all the black clouds concentrated and brought together into one great tempest that it might rush in one tremendous tornado upon the person of the great Redeemer and substitute. As when a thousand streamlets dash down the mountain side in the day of rain, and all meet in one deep swollen lake; that lake the Savior’s heart, those gushing torrents the sins of us all who are here described as making a full confession of our sins. Or to take a metaphor not from nature but from commerce; suppose the debts of a great number of persons to be gathered up, the scattered bonds and bills that are to be honored or dishonored on such and such a day, all these laid upon one person who undertakes the responsibility of meeting every one of them without a single assistant; such was the condition of the Savior; [God] made to meet on him the debts of all his people so that he became responsible for all the obligations of every one of those whom his Father had given him whatsoever their debts might be. ...all sins are made to meet, and then having met together and been tied up in one crushing load the whole burden is laid upon him.” Hallelujah! Hallelujah, that all of my life’s sins were wrapped up and placed on my substitute. Hallelujah, that he bore my burden for me. Praise God forever and ever. Fire of Judgment The fifth type is the fire of judgment ready to consume Isaac. Fire is consistently a picture of the holiness of God and His hatred of sin, and of His wrath poured out, like fire and brimstone poured down on Sodom and Gomorrah. Hebrews 12:29 says that “our God is a consuming fire.” The sacrifice was to be bound and laid on an altar and burned up, his blood poured out and he was to be burned up. So Abraham carried the fire up Mount Moriah with which to consume the body of his son, his only son whom he loved. Christ’s body was not burned up, but there is a different kind of fire at work in him. First, there is a burning zeal inside Christ’s heart. When Jesus cleansed the temple, driving out the money changers with a whip, John 2:17 says, “His disciples remembered that it was written, ‘Zeal for your house will consume me.’” The word “consume” is used of being literally consumed by fire. There was a fire inside his heart for the purity and holiness of God’s house. It is ironic that that was the very thing that got him killed physically, because he messed up the business of religion. He was hitting them in the pocketbook, hitting their income. That zeal burned him up in that it destroyed him — he was killed as a result of that zeal. That is one sense. How much more the cup of God’s wrath that he drank to the bottom? Jesus went to Gethsemane. Matthew 26:39 says, “And going a little farther he fell on his face and prayed, saying, 'My Father, if it be possible, let this cup pass from me; nevertheless, not as I will, but as you will.’” Revelation describes the cup very well when it speaks of those that are condemned. Revelation 14:10 says, “…he also will drink the wine of God's wrath, poured full strength into the cup of his anger, and he will be tormented with fire and sulfur.” Jesus drank that cup at Calvary. He drank your hell and mine, if you are a Christian, to the bottom. Two others were crucified with him that day, but they did not drink the cup of God’s wrath. Jesus alone drank that. Death Penalty Sixth, the death penalty is required. From the beginning, God established that “the wages of sin is death.” [Romans 6:23] In Genesis 2:17, He said, “of the tree of the knowledge of good and evil you shall not eat, for in the day that you eat of it you shall surely die.” The command to sacrifice Isaac was not in any way unjust, for Isaac was a sinner and he deserved to die. The wages of sin is death. Ezekiel 18:4 says, “…every living soul belongs to me, the father as well as the son — both alike belong to me. The soul who sins is the one who will die.” Later in Israel’s history, when God killed the firstborn of all of Egypt, the Passover lamb had to be sacrificed in their place so that the firstborn of Israel would not also perish. Isaac deserved to die, as do all who have sinned, which is all of us. “For all have sinned and fall short of the glory of God.” [Romans 3:23] Jesus was born to die, among other things. He had to lay down his life as an atoning sacrifice for our sins. Isaac was not merely to be sold into slavery, not merely to be wounded. He was to be put to death — the death penalty had to be paid. Jesus was born to die. 1 Peter 3:18 “For Christ died for sins once for all, the righteous for the unrighteous, to bring you to God. He was put to death in the body…” Jesus paid the death penalty. We are sinners; we violate the Ten Commandments and the two Great Commandments every day. We are to love the Lord our God with all our heart, soul, mind and strength and to love our neighbors ourself and we do not do so. God has taken up all of that selfishness and pride and lust and evil and put it on Jesus; he died the death penalty we deserve. Moment of Revelation Seventh, there was the shocking moment of revelation. Isaac did not know as he started up that mountain that he was the sacrifice. Genesis 22:7-8 says, “Isaac spoke up and said to his father Abraham, ‘Father?’ ‘Yes, my son?’ Abraham replied. ‘The fire and wood are here,’ Isaac said, ‘but where is the lamb for the burnt offering?’ Abraham answered, ‘God himself will provide the lamb for the burnt offering, my son.’ And the two of them went on together.” At some point, Isaac realized that he was the sacrifice. We do not know when Abraham told him — halfway up the mountain or after they had arranged the wood, or when Abraham began to bind him. But at some point, he realized he was the sacrifice. It must have been quite a shock to realize. How would this be fulfilled in Christ? Here we are on holy ground, brothers and sisters. In his deity, Jesus always knew what the Father wanted him to do. But when Mary wrapped him up in swaddling cloths and lay him in a manger, did he know he was born to die? No. Jesus submitted himself to a normal growing process. Luke 2:52 says, “And Jesus grew in wisdom and stature, and in favor with God and men.” At some point, long before he began his public ministry, the Father began to communicate to his Son, “You will die as a sacrifice.” Jesus himself spoke of this in John 10:17-18: “The reason my Father loves me is that I lay down my life — only to take it up again. No one takes it from me, but I lay it down of my own accord. I have authority to lay it down and authority to take it up again. This command I received from my Father.” When did he receive that command from his Father? Before the foundation of the world. But when did Jesus in his human consciousness know that command he had received from his Father? It is not clear, but it was before he began his public ministry. Again and again, he testified that he had to be sacrificed, but he did not know when he was wrapped as a baby and laid in the manger. He grew into that knowledge, and step by step the Father educated him. Then we come to Gethsemane where the shocking realization reaches its peak before the cross. Mark 14:32-33 in the KJV says, “And they came to a place which was named Gethsemane: and he saith to his disciples, Sit ye here, while I shall pray. And he taketh with him Peter and James and John, and began to be sore amazed, and to be very heavy…” The King James Version is one of the most accurate translations ever done, but English has changed. Why was he sore amazed? The Greek means to be astonished or amazed, usually connected with Jesus’ miracles, and the crowd’s reaction to them. The Greek root comes from the sense of being struck or shocked by something, perhaps new or unexpected. Why did Mark use this expression regarding Jesus? Jesus knew he would die. It was what it would be like to drink the cup of God’s wrath. Imagine listening to a game on crackly AM radio and comparing that experience to watching it on state-of-the-art HD TV. You get the idea, you get the facts, you get what has happened, but there is an entirely different level of understanding. That was what Jesus was sore amazed at in Gethsemane. God did something inside him, showed him what it would be like to drink that cup, and he was struck to the ground and blood started coming out of his pores. Mel Gibson cannot depict it — no movie can; the best he could do was a nonverbal expression of anguish and sorrow and astonishment, as if to say, “That’s what it’s like to drink the cup?” “Yes. Will you still do it?” Willingly Yielded to Death Eighth, we see the greatest, most heroic decision that was ever made in history: “Father, Abba, if it is possible for this cup, which you are now showing me more fully and completely, to pass from me, may it be so. Yet, not as I will, but as You will.” That was an act of obedience. Isaac willingly yielded to his death. He was a young man strong enough to carry a bunch of wood up a mountain, walking with his 100-year-old father whose body was as good as dead. It would not have been much of a contest. Not to be irreverent, but imagine Isaac saying, “Oh, no! You’re not doing that to me!” What chance did Abraham have? Who was stronger? Who was faster? If Isaac had not wanted to be sacrificed, he would not have submitted. He must have been in his 20s or so, and he said, “I will do it.” Why then was he bound? Because sacrifices were bound, and if they had gone through with what God commanded, it would have been a mercy to Isaac to bind him. He willingly yielded to death. Here I find my salvation: “Going a little farther, he fell with his face to the ground and prayed, ‘My Father, if it is possible, may this cup be taken from me. Yet not as I will, but as you will.’” [Matthew 26:39] This is the sublime courage of Jesus Christ. Never in history has anyone shown that much courage. He took that burden, he took the cup, he accepted it and said, “I’ll drink it.” Romans 5:19 says, “For just as through the disobedience of the one man the many were made sinners, so also through the obedience of the one man the many will be made righteous.” Jesus obeyed his Father; he drank the cup. God showed it more fully to him in the garden so that he could make the fully-informed decision of his own free will to die in my place as my substitute. Knowing what it would entail, he did it anyway. Martin Luther said, “Never a man feared death so much as this man” but he did not fear the physical death that the robbers on his left and right also faced. No, he feared hell, which is something to be feared. Jesus himself feared it. “Fear not those who kill the body and after that can do nothing to you. Fear the one who has power to send you to hell.” Jesus willingly went to hell on the cross and drank the cup of wrath. Review and Applications We have considered eight points of connection between Abraham and Isaac and the Gospel of Jesus Christ. The story in Genesis 22 depicts types of the Gospel in these ways: The father-son relationship in which the son would be sacrificed. A predetermined deliberate choice by the Father. The father and the son were alone, humanly speaking in Genesis, just as the heavenly Father and the heavenly Son alone work salvation for us. The son carried his own wood — Isaac his wood for the fire and Jesus the wood of his cross; he also bore our sins, if we have trusted in him. The fire of judgment, ready to consume Isaac; the fire of hell, consuming Christ spiritually. The death penalty was required — not paid in Isaac’s case, but paid in Jesus’ case. “What Abraham was asked to do, he has done. He’s offered his only son.” Isaac had a shocking moment of revelation when at last he realized that he was to be the substitute; Jesus had been instructed all along in his human understanding that he would be a substitute and in Gethsemane and had a more full revelation. Isaac willingly yielded himself to death and so also did Jesus Christ What applications can we take from this? Read this account with a sense of wonder, amazement, and astonishment. This Gospel was not thrown together but has been being worked out for thousands of years of history. This is my salvation and yours too, if you trust him. Trust in Christ, repent of your sins. That great burden that you have been carrying around, maybe you carried it in here today — a sin habit, wickedness — give it to Christ. He is the only substitute. Nothing but the blood of Jesus can wipe away your sin. Give it to him. And if you are tempted to waver and quaver in your faith, get back in the Word. Read Genesis 22. Review these types and try to see more types of the Gospel in this account. Think about it, wonder about it, and build your faith again through the Word.