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This week: Ian Welsh and Anamya Anurag explores emerging food trends in North America, including farmer inclusion specifically for underrepresented farmers and continued uncertainty around input costs, labour availability and policies. Plus: a short preview of a interview coming up in the Innovation Forum podcast with palm oil company Musim Mas, social business Livelihood Ventures and impact NGO SNV, discussing regenerative agriculture in Indonesia. Hear from SNV's Rizki Pandu Parma talk about how farmers are being empowered by region ag projects. Host: Ian Welsh Click here for more information on upcoming complimentary webinars. To learn more about food innovations, join us at the future of food and beverage forum USA (Minneapolis, 28-29 May) . Click here.
Povodom pravoslavnog Božića, Srpsko narodno vijeće održalo je tradicionalni prijem za državni vrh i uglednike. Do su premijer i ministri bili na domjenku SNV-a, koalicijski Domovinski pokret podržao je osnivanje autokefalne Hrvatske pravoslavne crkve. Katolički vjernici obilježili su Bogojavljenje.
The 2024 Premium Cigar Association (PCA) Trade Show was the fourth one for Howard G Cigars. 2024 has certainly been a pivotal year for Howard G Cigars. Earlier this year, Howard G announced it had ended direct-to-consumer sales to focus on selling through retailers. This year, the focus for Howard G Cigars was on its core Magic Stick line. Magic Stick is a line that is offered in three blends: Connecticut, Habano, and Cameroon. This year Howard G would round out the series, resulting in the three blends now having the same sizes. PCA 2024 Report: https://wp.me/p6h1n1-sNv
The 2024 Premium Cigar Association (PCA) Trade Show was the fourth one for Howard G Cigars. 2024 has certainly been a pivotal year for Howard G Cigars. Earlier this year, Howard G announced it had ended direct-to-consumer sales to focus on selling through retailers. This year, the focus for Howard G Cigars was on its core Magic Stick line. Magic Stick is a line that is offered in three blends: Connecticut, Habano, and Cameroon. This year Howard G would round out the series, resulting in the three blends now having the same sizes. PCA 2024 Report: https://wp.me/p6h1n1-sNv
REDIFFUSIONQu'est-ce qui se cache derrière ce drôle de nom ? Le syndrome du nez vide n'est pas très évocateur de ce que ressentent les personnes qui en souffrent. Par nez vide, il faudrait plutôt comprendre nez plein : ce syndrome donne l'impression d'avoir le nez bouché en permanence, et ce même en l'absence de rhume. Il survient souvent après une opération, la turbinectomie, dont l'objectif est justement d'éviter les obstructions respiratoires.Comment se manifeste le syndrome du nez vide ? Quelles sont les conséquences sur la vie des personnes atteintes, et comment résoudre ce problème gênant au quotidien ?Les causes susceptibles d'entrainer un SNVIl faut d'abord savoir que le syndrome du nez vide est iatrogène, c'est-à-dire qu'il survient à la suite d'un acte réalisé par un médecin, le plus souvent de façon chirurgicale. Les causes du SNV concernent donc toutes les chirurgies réalisées au niveau du nez qui peuvent endommager les tissus internes producteurs de mucus, appelés les cornets. L'opération initiale peut avoir pour but d'améliorer la respiration d'un patient atteint de sinusite chronique ou de rhinites à répétition. Elle peut aussi concerner une chirurgie plastique, une cautérisation ou encore une turbinoplastie totale, qui consiste en l'ablation des cornets du nez.Or, les cornets sont des structures très importantes pour le nez, qui aident à réchauffer, filtrer et humidifier l'air lors de l'inspiration. Si l'ablation de ces structures a été trop poussée ou qu'elles ont été abimées lors d'un acte chirurgical, elles ne peuvent plus remplir leurs fonctions.Les conséquences d'un SNV sur la qualité de vie des patientsSécheresse nasale permanente, sensation d‘obstruction des narines, douleurs à la tête et au front, sinusites chroniques, écoulements, croûtes à l'intérieur du nez, difficultés à respirer la nuit, essoufflement chronique, impossibilité à faire du sport : les conséquences du syndrome du nez vide sont graves et nombreuses. Elles induisent parfois la perte de l'odorat et du goût, ou des infections et inflammations à répétition.Forcément, la qualité de vie des personnes touchées s'en ressent. Certaines doivent cesser la pratique d'activités qui leur plaisaient, d'autres perdent l'appétit, l'envie de sortir, le plaisir de bien dormir. Il existe un vrai risque psychologique de développer une dépression, des troubles anxieux et du stress chronique.Comment éviter le SNV ?Face à l'importance des symptômes du SNV, la Haute autorité de santé a publié en 2022 une recommandation de bonnes pratiques pour limiter les risques de développer un syndrome du nez vide après une opération du nez. Elle recommande entre autres de toujours privilégier les gestes chirurgicaux les moins invasifs et de positionner la turbinectomie en dernière intention. Dans ce cas, il est essentiel de préserver le maximum de surface des cornets possible. Le patient doit aussi être bien informé des risques de l'opération... Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
REDIFFUSION Qu'est-ce qui se cache derrière ce drôle de nom ? Le syndrome du nez vide n'est pas très évocateur de ce que ressentent les personnes qui en souffrent. Par nez vide, il faudrait plutôt comprendre nez plein : ce syndrome donne l'impression d'avoir le nez bouché en permanence, et ce même en l'absence de rhume. Il survient souvent après une opération, la turbinectomie, dont l'objectif est justement d'éviter les obstructions respiratoires. Comment se manifeste le syndrome du nez vide ? Quelles sont les conséquences sur la vie des personnes atteintes, et comment résoudre ce problème gênant au quotidien ? Les causes susceptibles d'entrainer un SNV Il faut d'abord savoir que le syndrome du nez vide est iatrogène, c'est-à-dire qu'il survient à la suite d'un acte réalisé par un médecin, le plus souvent de façon chirurgicale. Les causes du SNV concernent donc toutes les chirurgies réalisées au niveau du nez qui peuvent endommager les tissus internes producteurs de mucus, appelés les cornets. L'opération initiale peut avoir pour but d'améliorer la respiration d'un patient atteint de sinusite chronique ou de rhinites à répétition. Elle peut aussi concerner une chirurgie plastique, une cautérisation ou encore une turbinoplastie totale, qui consiste en l'ablation des cornets du nez. Or, les cornets sont des structures très importantes pour le nez, qui aident à réchauffer, filtrer et humidifier l'air lors de l'inspiration. Si l'ablation de ces structures a été trop poussée ou qu'elles ont été abimées lors d'un acte chirurgical, elles ne peuvent plus remplir leurs fonctions. Les conséquences d'un SNV sur la qualité de vie des patients Sécheresse nasale permanente, sensation d‘obstruction des narines, douleurs à la tête et au front, sinusites chroniques, écoulements, croûtes à l'intérieur du nez, difficultés à respirer la nuit, essoufflement chronique, impossibilité à faire du sport : les conséquences du syndrome du nez vide sont graves et nombreuses. Elles induisent parfois la perte de l'odorat et du goût, ou des infections et inflammations à répétition. Forcément, la qualité de vie des personnes touchées s'en ressent. Certaines doivent cesser la pratique d'activités qui leur plaisaient, d'autres perdent l'appétit, l'envie de sortir, le plaisir de bien dormir. Il existe un vrai risque psychologique de développer une dépression, des troubles anxieux et du stress chronique. Comment éviter le SNV ? Face à l'importance des symptômes du SNV, la Haute autorité de santé a publié en 2022 une recommandation de bonnes pratiques pour limiter les risques de développer un syndrome du nez vide après une opération du nez. Elle recommande entre autres de toujours privilégier les gestes chirurgicaux les moins invasifs et de positionner la turbinectomie en dernière intention. Dans ce cas, il est essentiel de préserver le maximum de surface des cornets possible. Le patient doit aussi être bien informé des risques de l'opération... Learn more about your ad choices. Visit megaphone.fm/adchoices
Emma and Milk head back to SnV to cover some highly requested characters. Emma solves a complicated equation. Milk has to make some changes.
PODCASTER SENIOR: Camilla Rocchi;PODCASTER JUNIOR: Tommaso Cillotto;RAZIONALE:Il sistema nervoso vegetativo è uno dei sistemi maggiormente integrati del nostro organismo, in connessione con i sistemi afferenti ed efferenti somatici e con le strutture che sottendono i nostri processi emozionali, volto al mantenimento dell' equilibrio omeostatico, implicato nella modulazione dei nostri comportamenti, del sonno, di risposte neuro endocrine e neuro immunologiche. Esso è controllato dal network autonomico centrale, una vasta rete di connessioni distribuita su più livelli gerarchici caudo-cranialmente dal midollo sino alla corteccia. Data questa forte interconnessione il SNV può venire alterato, a qualsiasi livello del SNC o SNP, in senso di iper o ipofunzione, in numerosi processi patologici, che possono comprometterlo in modo isolato (ad esempio nella ganglionopatia autonomia autoimmune, nella PAF o per l'uso di Farmaci) o in associazione ad altre manifestazioni neurologiche/sistemiche come nell'ambito di:1. disordini neurodegenerativi (di cui in primis sinucleinopatie, prioniche, leucoencefalopatie ereditarie)2. In casi di Mielopatie di varia natura 3. In corso di NEUROPATIA PERIFERICA - su base autoimmunitaria/paraneoplastiche - endocrino/metabolica/tossica/Infettiva (HIV, Lyme) - Ereditaria: in quest'ambito citiamo Amiloidosi, neuropatia sensoriale autonomica (es.HSAN3- Sdr.Riley Day), Fabry, Canalopatie del sodio, Porfiria acuta intermittente 4. Ricordiamo infine il frequente coinvolgimento autonomico in alcuni disordini della giunzione NM (botulismo, LEMS) 5. Altre forme rare: deficit Dopamina Beta idrossilasi; Forme “segmentarie/distrettuali”: Sindrome di Ross
Qu'est-ce qui se cache derrière ce drôle de nom ? Le syndrome du nez vide n'est pas très évocateur de ce que ressentent les personnes qui en souffrent. Par nez vide, il faudrait plutôt comprendre nez plein : ce syndrome donne l'impression d'avoir le nez bouché en permanence, et ce même en l'absence de rhume. Il survient souvent après une opération, la turbinectomie, dont l'objectif est justement d'éviter les obstructions respiratoires.Comment se manifeste le syndrome du nez vide ? Quelles sont les conséquences sur la vie des personnes atteintes, et comment résoudre ce problème gênant au quotidien ?Les causes susceptibles d'entrainer un SNVIl faut d'abord savoir que le syndrome du nez vide est iatrogène, c'est-à-dire qu'il survient à la suite d'un acte réalisé par un médecin, le plus souvent de façon chirurgicale. Les causes du SNV concernent donc toutes les chirurgies réalisées au niveau du nez qui peuvent endommager les tissus internes producteurs de mucus, appelés les cornets. L'opération initiale peut avoir pour but d'améliorer la respiration d'un patient atteint de sinusite chronique ou de rhinites à répétition. Elle peut aussi concerner une chirurgie plastique, une cautérisation ou encore une turbinoplastie totale, qui consiste en l'ablation des cornets du nez.Or, les cornets sont des structures très importantes pour le nez, qui aident à réchauffer, filtrer et humidifier l'air lors de l'inspiration. Si l'ablation de ces structures a été trop poussée ou qu'elles ont été abimées lors d'un acte chirurgical, elles ne peuvent plus remplir leurs fonctions.Les conséquences d'un SNV sur la qualité de vie des patientsSécheresse nasale permanente, sensation d‘obstruction des narines, douleurs à la tête et au front, sinusites chroniques, écoulements, croûtes à l'intérieur du nez, difficultés à respirer la nuit, essoufflement chronique, impossibilité à faire du sport : les conséquences du syndrome du nez vide sont graves et nombreuses. Elles induisent parfois la perte de l'odorat et du goût, ou des infections et inflammations à répétition.Forcément, la qualité de vie des personnes touchées s'en ressent. Certaines doivent cesser la pratique d'activités qui leur plaisaient, d'autres perdent l'appétit, l'envie de sortir, le plaisir de bien dormir. Il existe un vrai risque psychologique de développer une dépression, des troubles anxieux et du stress chronique.Comment éviter le SNV ?Face à l'importance des symptômes du SNV, la Haute autorité de santé a publié en 2022 une recommandation de bonnes pratiques pour limiter les risques de développer un syndrome du nez vide après une opération du nez. Elle recommande entre autres de toujours privilégier les gestes chirurgicaux les moins invasifs et de positionner la turbinectomie en dernière intention. Dans ce cas, il est essentiel de préserver le maximum de surface des cornets possible. Le patient doit aussi être bien informé des risques de l'opération... Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Qu'est-ce qui se cache derrière ce drôle de nom ? Le syndrome du nez vide n'est pas très évocateur de ce que ressentent les personnes qui en souffrent. Par nez vide, il faudrait plutôt comprendre nez plein : ce syndrome donne l'impression d'avoir le nez bouché en permanence, et ce même en l'absence de rhume. Il survient souvent après une opération, la turbinectomie, dont l'objectif est justement d'éviter les obstructions respiratoires. Comment se manifeste le syndrome du nez vide ? Quelles sont les conséquences sur la vie des personnes atteintes, et comment résoudre ce problème gênant au quotidien ? Les causes susceptibles d'entrainer un SNV Il faut d'abord savoir que le syndrome du nez vide est iatrogène, c'est-à-dire qu'il survient à la suite d'un acte réalisé par un médecin, le plus souvent de façon chirurgicale. Les causes du SNV concernent donc toutes les chirurgies réalisées au niveau du nez qui peuvent endommager les tissus internes producteurs de mucus, appelés les cornets. L'opération initiale peut avoir pour but d'améliorer la respiration d'un patient atteint de sinusite chronique ou de rhinites à répétition. Elle peut aussi concerner une chirurgie plastique, une cautérisation ou encore une turbinoplastie totale, qui consiste en l'ablation des cornets du nez. Or, les cornets sont des structures très importantes pour le nez, qui aident à réchauffer, filtrer et humidifier l'air lors de l'inspiration. Si l'ablation de ces structures a été trop poussée ou qu'elles ont été abimées lors d'un acte chirurgical, elles ne peuvent plus remplir leurs fonctions. Les conséquences d'un SNV sur la qualité de vie des patients Sécheresse nasale permanente, sensation d‘obstruction des narines, douleurs à la tête et au front, sinusites chroniques, écoulements, croûtes à l'intérieur du nez, difficultés à respirer la nuit, essoufflement chronique, impossibilité à faire du sport : les conséquences du syndrome du nez vide sont graves et nombreuses. Elles induisent parfois la perte de l'odorat et du goût, ou des infections et inflammations à répétition. Forcément, la qualité de vie des personnes touchées s'en ressent. Certaines doivent cesser la pratique d'activités qui leur plaisaient, d'autres perdent l'appétit, l'envie de sortir, le plaisir de bien dormir. Il existe un vrai risque psychologique de développer une dépression, des troubles anxieux et du stress chronique. Comment éviter le SNV ? Face à l'importance des symptômes du SNV, la Haute autorité de santé a publié en 2022 une recommandation de bonnes pratiques pour limiter les risques de développer un syndrome du nez vide après une opération du nez. Elle recommande entre autres de toujours privilégier les gestes chirurgicaux les moins invasifs et de positionner la turbinectomie en dernière intention. Dans ce cas, il est essentiel de préserver le maximum de surface des cornets possible. Le patient doit aussi être bien informé des risques de l'opération... Learn more about your ad choices. Visit megaphone.fm/adchoices
The Chips Avengers assemble once again! Reva Goujon of the Rhodium Group, JP Kleinhans of the European think tank SNV, Jay Goldberg of Digits and Dollars, and Dylan Patel, who writes SemiAnalysis. In this episode of ChinaTalk, we all: Deep dive into the CHIPS Act's recent Notice of Funding Opportunity (NOFO); Discuss the potentially existential impact of AI on global power dynamics; Consider the true intentions of the October 2022 export controls — from military constraining China to crippling manufacturing in the broader economy; Muse about the potential for a "splinternet" to emerge as countries around the world — in particular, the US, China, EU members states — adopt different standards and regulations for their tech industries; And more! Outro music: https://www.youtube.com/watch?v=m1_Amc4Ysv0 Learn more about your ad choices. Visit megaphone.fm/adchoices
The Chips Avengers assemble once again! Reva Goujon of the Rhodium Group, JP Kleinhans of the European think tank SNV, Jay Goldberg of Digits and Dollars, and Dylan Patel, who writes SemiAnalysis. In this episode of ChinaTalk, we all: Deep dive into the CHIPS Act's recent Notice of Funding Opportunity (NOFO); Discuss the potentially existential impact of AI on global power dynamics; Consider the true intentions of the October 2022 export controls — from military constraining China to crippling manufacturing in the broader economy; Muse about the potential for a "splinternet" to emerge as countries around the world — in particular, the US, China, EU members states — adopt different standards and regulations for their tech industries; And more! Outro music: https://www.youtube.com/watch?v=m1_Amc4Ysv0 Learn more about your ad choices. Visit megaphone.fm/adchoices
Wie resilient ist meine IT-Infrastruktur und wie sichere ich diese am besten ab? Wie angriffbar wird mein Unternehmen durch die Integration von Robotern? Wie läuft eine Cyberattacke ab und welche Bereiche sind betroffen? Für diese wichtigen und gleichzeitig sehr schwierigen Fragen hat Victor einen Gast eingeladen, der sich mit Cybersicherheit bestens auskennt. Dr. Sven Herpig, Leiter für Internationale Cybersicherheitspolitik bei der Stiftung Neue Verantwortung, beantwortet Fragen, die sich jedes Logistik- oder Produktionsunternehmen schon einmal gestellt hat. Anhand eines realen Beispiels erklärt Sven, wie ein Cyberangriff auf die Logistikkette aussehen kann und welche nachteiligen Auswirkungen entstehen können. Es geht um private und staatliche Akteure, um geopolitsche Prozesse und um Hintertüren in der Software. Zum Schluss beschreibt Sven, wie sich Unternehmen vor Cyberangriffen schützen können und Strategien entwickeln müssen, um nach einem Angriff schnell wieder operativ aktiv sein. Verpasse nicht diese spannende Folge! Viel Spaß beim Anhören der siebten Episode von “Roboter in der Logistik”. Zu unserem Gast: Dr. Sven Herpig ist Leiter für Internationale Cybersicherheitspolitik beim Think Thank “Stiftung Neue Verantwortung (SNV)”. Dort befasst sich Sven vorrangig mit der deutschen Cyber-Sicherheitsarchitektur, Verschlüsselungspolitik, Staatlichem Hacken und Schwachstellenmanagement, dem Schutz der Wahlen in vernetzten Gesellschaften und der Sicherheit von Machine Learning Anwendungen. Bevor er zur SNV kam, arbeitete Sven mehrere Jahre bei deutschen Bundesbehörden im Bereich IT-Sicherheit. Auf der Seite des Bundesamts für Sicherheit in der Informationstechnik findest du weitere Informationen, um dich und dein Unternehmen vor Cyberkriminalität zu schützen: www.bsi.bund.de. LinkedIn Profile Victor Splittgerber: https://www.linkedin.com/in/victor-splittgerber-93547290 Dr. Sven Herpig: https://www.linkedin.com/in/sven-herpig-88b253209/ Nähere Infos zu WAKU Robotics, den Expertinnen und Experten für mobile Roboter in der Logistik und Produktion, gibt es auf www.waku-robotics.com.
Hello and welcome to the Migration & Diaspora Podcast, with me your co-host, Aurore. Today, I'm joined by Fridah Ntarangwi, Founder and Managing Director of Zidi Circle to talk about how Zidi Circle is aiming to bridge the African diaspora venture funding gap. About Fridah Originally from Kenya, Fridah founded the first-ever diaspora entrepreneurship incubator out of the Netherlands, Zidicircle supporting the diaspora and migrants with entrepreneurship training, mentorship, match-making and access to investment to succeed as entrepreneurs both in their countries of residence and home countries. Through her leadership, Zidicircle has collectively graduated hundreds diaspora entrepreneurs and impacted many households both in Europe and Africa. She has also managed several Diaspora Entrepreneurship Programmes including IOM's Connecting Diaspora for Development (CD4D), SNV's Green diaspora venture backers programme and Green-Diaspora SME Matching programme, the Diaspora-SME Forum and launched investment products like the Diaspora Venture Backers programme that trains aspiring diaspora investors on how to invest in startups and SMEs in host and home countries. Fridah was awarded by the EMEN project of the European Union (EU) for promoting inclusive entrepreneurship in the EU and was bestowed the Duisenberg title ‘Woman in Finance'. The Amsterdam's Municipality's initiative startup Amsterdam and the Silicon Canals recently listed Fridah as a top female entrepreneur in the Netherlands to watch in 2022. She is passionate about building an inclusive entrepreneurship and financing ecosystem for migrants, developing economies and women entrepreneurs. Fridah holds a bachelor of Commerce degree from the Catholic University of Eastern Africa and a Master of science in Finance from the Duisenberg school of Finance in the Netherlands. What we talk about In this interview, we talk about how the African diaspora can step in to bridge the VC funding gap on the continent and in the diaspora. We talk about the need to create investment opportunities and a culture of investing within the African diaspora, beyond traditional channels and how Zidi Circle supports this process. I'm excited for you to get into this interview, so I'd like to thank you, as always, for tuning in and please do enjoy the show. Links Connect with Zidi Circle: Website / Instagram / Twitter / Facebook Connect with Fridah: Linkedin / Twitter Check out all our episodes and subscribe at homelandsadvisory.com/podcast!
Misinformation and disinformation are pressing public issues. There has been a rapid spread of misinformation and disinformation. Sometimes we call them fake news. This happens online and offline and it affects everyone, every day. Receiving truthful and quality information is critical as we all depend on information to make decisions. At the personal level, we need accurate information to make decisions about health and who we vote for. And at the global level, we need established facts to make collective decisions on pressing issues. Such as pandemics climate change and resolving conflicts. The UN Secretary-General and his report 'Our Common Agenda' called the large-scale spread of disinformation and the undermining of scientifically established facts as an existential risk to humanity. In this episode, we will be speaking with Dr. Julian Jaursch, Project Director at the SNV in Berlin, working on Strengthening the Digital Public Space. Want to learn more about sustainable development and learning? Subscribe to SDG Learncast. Visit the UN SDG:Learn website at www.unsdglearn.org to get the latest learning offers on the 2030 Agenda and SDGs. The transcript of the podcast is available at https://www.unsdglearn.org/podcast/.
Hierdie week is dit weer motorsport-aksie tydens Wiele2Wiele vir die derde rondte vir die GR Cup by die Aldo Scribante renbaan, hulle gaan ry ook met die Opel Mokka en gesels oor Avontuur Afrika se oorkruis SNV (sportnutsvoertuie) avontuur. Wiele2Wiele op Facebook · Wiele2Wiele op Maroela Media
Hierdie week is dit weer motorsport-aksie tydens Wiele2Wiele vir die derde rondte vir die GR Cup by die Aldo Scribante renbaan, hulle gaan ry ook met die Opel Mokka en gesels oor Avontuur Afrika se oorkruis SNV (sportnutsvoertuie) avontuur.
A gestão sistemática, que muitas vezes também é chamada de quantitativa, é o tema chave do episódio 68 do RetornoCast. Convidamos Pedro Tiezzi, da SNV, e Luciano França, da Avantgarde Asset Management para falar sobre o tema. No bate-papo você vai entender o que de fato é a gestão sistemática, como ela se diferencia dos demais tipos de gestão do mercado financeiro, porque vem se destacando e, ainda vai descobrir os segredos por trás da gestão da Avantgarde Asset Menagement. Aperte o play e confira!
Ghana es el segundo mayor exportador de cacao del mundo. Pero cada vez hay más dificultades con el cultivo: plantaciones muy antiguas, enfermedades en los árboles y sequía creciente. En el oeste de Ghana, la ONG neerlandesa SNV intenta mejorar la situación.
Seeking to counter a microchip shortage, the EU unveiled a plan to boost manufacturing. Some $49bn in subsidies are proposed to try and ensure 20% of the world's microchips are produced in Europe by 2030. Jan-Peter Kleinhans from technology think tank SNV in Berlin assesses whether that is a realistic target. Also in the programme, the oil giant BP has posted $12.8bn in profits for the past year, its highest level for eight years. It has led to calls for a windfall tax on oil companies in the United Kingdom, as we hear from Tom Wilson, senior energy correspondent at the Financial Times. The BBC's Justin Rowlatt reports on new technologies that might help mitigate the environmental impact of so-called 'fast fashion', which are clothes that often end up in landfill. Plus, we explore the potential for robot cats and dogs, designed to interact with their owners, including mimicking their heartbeats and breathing, with Ted Fischer, co-founder of Ageless Innovation which is behind the devices.
Ghana ist weltweit der zweitgrößte Exporteur von Kakao. Überalterte Plantagen, Baumkrankheiten und die zunehmende Trockenheit bringen immer mehr Kakao-Farmer in Schwierigkeiten. Im Westen Ghanas versucht die niederländische NGO "SNV", das Blatt zu wenden.
Hans Øyvind Sagen vert ny dagleg leiar i Bryne FK. Han har vore SNV for salg i Akvagroup, og har erfaring som marknadssjef i Viking. Me høyrer med Geir Pollestad om kvifor valet falt på Sagen, og kjem attende seinare i dag med intervju med den nye daglege leiaren.
Simon Shares Tesla (NYSE code: TSLA) becomes the worlds 7th trillion-dollar company. Excellent Santova (JSE code: SNV) results. My bad pandemic crash sale. Decent Famous Brands* (JSE code: SSW) results. Implats (JsE code: IMP) wants to buy Royal Bafokeng Platinum (JSE code: RBP). Sibanye-Stillwater* (JSE code: SSW) buys two Brazilian mines for US$1billion and 19.99% investment in New Century Resources for US$46million. * I hold ungeared positions. Upcoming events; 04 November ~ JSE Power Hour: Bold predictions from SA's top broker 11 November ~ Investment Valuation with Keith McLachlan From the last week Satrix launches All Share ETF CoreShares dividend tax
Episode 348. Investigating myself. Topic: Bloom syndrome. How do some genetic diseases increase cancer risk? How is Bloom syndrome a particularly extreme example of this? How common is Bloom syndrome... and do I carry the gene for it?Twitter: @3minutelessonEmail: 3minutelesson@gmail.comNew episode every week day!Methodology notes:No functional or clinically relevant SNV or InDel variants were discovered in the BLM gene.
Alumni of the Education for Sustainability MSc will discuss the role that education for sustainability has played in their work and careers. The alumni on the panel will be drawn from different countries including Cameroon, Kenya and Zambia and from different fields including water policy, agriculture, civic rights, anti-corruption and education. They will offer a view onfuture developments in their own contexts, particularlyin relation to climate change. Session Lead: Dr Glen Strachan, Education for Sustainability Programme, School of Law and Social Sciences, LSBU. Joined by: • Stephen Asek, Founding Board Member of Solidarity 2020, Cameroon • Euphresia Luseka, Water Governance Consultant, Kenya • Rae Merrigan, Teacher, Indonesia • Robson Nyirenda, Project Manager Opportunities for Youth Employment, SNV, Zambia School: Law and Social Sciences.
Simon Shares Santova (JSE code: SNV) were very solid and they are now truly a global logistics business. Distell (JSE code: DGH) announced that Heineken wants a 'majority' stake in the company. Details are scant with major shareholders being PIC and Remgro (JSE code: REM) both just over 31%. But does the majority mean they want the cider business or +50% of the shares which would trigger a mandatory offer to minorities? This of course after Heineken threatened to take their beer and go home last year during the alcohol ban. hmmm, wasn't it just last year Heineken was hating on us so much they was canceling projects and threatening to take their beer and go home .. — Simon Brown (@SimonPB) May 18, 2021 Balwin (JSE code: BWN) & Calgro M3 (JSE code: CGR) results both showed a tough year. But I like this space. Calgro offering its units at the R500k price point (R4,000 monthly bond costs) while Balwin starts at a little under R1million to around R2million. So different markets. Redefine (JSE code: RDF) results saw loan-to-value (LTV) improving but what struck me is that they value properties twice a year. Most doing it over a rolling three years. Local CPI hit a 14-month high in April, mainly driven by rising transport and food prices. The rate was 4.4%, up from 3.2% in March. Thursday is the MPC rate decision, no change expected. Eurozone April CPI +0.6% on Month, +1.6% on Year. Core CPI +0.5% on Month; +0.7% on Year Crypto crashing, entire crypto market cap is off 20% today on news China is cracking down (again). * I hold ungeared positions. Upcoming events; 27 May ~ JSE Power Hour: Manage your money like a rock star! jjjjj What's with the 'special' shares? Special shares usually with high voting rights and often with limited or zero economic rights. They enable insiders to retain voting control even while they may not actually control the company. The most well known are the Naspers~N (JSE code: NPN) A shares that give control to a few parties. Shoprite* (JSE code: SHP) has the same for Christo Wiese which he tried to sell back to the company. But they have zero economic rights and only are votable by Wiese More recently it surprised many that while Remgro (JSE code: REM) owns a little over 31% of Distell (JSE code: DGH) they ave a pile of B shares that gives them 56% voting control. In the older days, companies used pyramid structures, but those have long since largely left the JSE and no new ones can be listed. The challenge is how to know about them? The annual report will detail them. Generally, they don't matter massively, until they do. And then they matter. Wiese failed to receive the required number of votes to get back onto the Shoprite board in 2018, but then he used his special shares to basically override shareholders. Subscribe to our feed here Sign up for email alerts as a new show goes live Subscribe or review us in iTunes JSE – The JSE is a registered trademark of the JSE Limited. JSE Direct is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
Dziś Wydanie Specjalne... Nova Cassiopei zmienia swój blask w bardzo nietypowy sposób.... Czy tak będzie wyglądał efekt końcowy wybuchu tej gwiazdy... ??? Milego słuchania...
Why Taiwan isn't making enough computer chips. Ed Butler speaks to Jan-Peter Kleinhans, head of technology and geopolitics at SNV, a German think tank, about the central role of Taiwan in the complex global supply chain of semiconductors. The BBC's Theo Leggett explains why the car industry has been particularly hit by the shortage of chips. And Shelley Rigger, professor of East Asian politics at Davidson University in the US, discusses the growing significance of Taiwan in the technology war between China and the US. (Photo: A man walks past a company logo at the headquarters of the world's largest semiconductor maker TSMC in Taiwan, Credit: Getty Images)
Refugees from Ethiopia are currently fleeing across the border into Sudan. If this crisis plays out like many do, big aid agencies will soon begin setting up shop, organising camps, handing out food and water, and leading an organised response to those refugees. But what if things were done differently? In this episode, Jeremy and Heba talk to three disruptors about their visions for alternative humanitarian action: Muthoni Wanyeki, the Regional Director for Africa at the Open Society Foundations; Paul Currion, recovering aid worker and reluctant innovator; and Simon O'Connell, the former head of Mercy Corps UK who is about to take on a role as CEO of SNV, an international development organisation based in The Netherlands.
Jess and Spencer discuss chapters 8-10 of 'Twilight,' examine the story through the theme of "Perception" and how it compares to 'The Sun Also Rises,' and take a deep dive into the world of cars with a lesson on the notorious SNV. --- Support this podcast: https://anchor.fm/twilitpod/support
Andrew and special guests Kendra and Edd Gabriel discuss Sects and Violets as a whole, and how it differs from Trouble Brewing. This is the first episode of a new season! The coming episodes will each focus on a different character from Sects and Violets, getting back into our normal rhythm of character discussions. However, we wanted to have this episode first to set a baseline for the whole edition, so that each individual episode can assume some degree of familiarity with the nuances of SnV. Each episode of the Cult of the Clocktower is (usually) about a different character from the game Blood on the Clocktower by the Pandemonium Institute. Andrew Nathenson and a special guest discuss the character in three parts, including strategies for playing as, bluffing as, and being the Storyteller for that character. For feedback and questions, please email cultoftheclocktower@gmail.com The music used at the start and end of the show is by TeknoAXE, who can be found at teknoaxe.com
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.10.244848v1?rss=1 Authors: Nicholls, S. M., Aubrey, W., de Grave, K., Schietgat, L., Creevey, C. J. M., Clare, A. Abstract: Motivation: Population-level genetic variation enables competitiveness and niche specialization in microbial communities. Despite the difficulty in culturing many microbes from an environment, we can still study these communities by isolating and sequencing DNA directly from an environment (metagenomics). Recovering the genomic sequences of all isoforms of a given gene across all organisms in a metagenomic sample would aid evolutionary and ecological insights into microbial ecosystems with potential benefits for medicine and biotechnology. A significant obstacle to this goal arises from the lack of a computationally tractable solution that can recover these sequences from sequenced read fragments. This poses a problem analogous to reconstructing the two sequences that make up the genome of a diploid organism (i.e. haplotypes), but for an unknown number of individuals. Results: The problem of single individual haplotyping (SIH) was first formalised by Lancia et al in 2001. Now, nearly two decades later, we discuss the complexity of "haplotyping" metagenomic samples, with a new formalisation of Lancia et al's data structure that allows us to effectively extend the single individual haplotype problem to microbial communities. This work describes and formalizes the problem of recovering genes (and other genomic subsequences) from all individuals within a complex community sample: which we term the metagenomic individual haplotyping (MIH) problem. We also provide software implementations of our proposed pairwise single nucleotide variant (SNV) co-occurrence matrix and greedy graph traversal algorithm. Availability and implementation: Our reference implementation of the described pairwise SNV matrix (Hansel) and greedy haplotype path traversal algorithm (Gretel) are open source, MIT licensed and freely available online at github.com/samstudio8/hansel and github.com/samstudio8/gretel, respectively. Copy rights belong to original authors. Visit the link for more info
The call to change the balance of power in development cooperation is getting louder and louder. It is time for more local ownership of the global agenda, everyone seems to agree. There is even a real movement under the hashtag #ShiftThePower. The development community has been talking about this for decades now, but what has changed? In this new Podcast series of Disrupt Development I am going unpack the #ShiftThePower debate with great minds. In this episode together with Evelijne Bruning we are going to talk about the circus of development cooperation, how development professionals are the accountants of change instead of the driver of change, the power of communities and together we will share tips for organisations who received new funding for programmes. Evelijne Bruning is executive director of The Hunger Project Netherlands, an organization committed to the sustainable end of world hunger. Evelijne is also one of the leaders of the The Movement for Community Led Development https://mcld.org/. Please visit this website if you / your organisations wants to become part of this movement.Before Evelijne joined The Hunger Project, she worked as editor-in-chief of Capacity.org and Vice-Versa - the Dutch trade development magazine - and as microcredit advisor to SNV in Vietnam. Until 2019 she wrote columns for De Dikke Blauwe - the professional journal for philanthropy. Evelijne is a much sought-after chairman and discussion leader in the field of development cooperation, and she is a member of various boards, including World in Progress, Partos and Both Ends. She is a headstrong and unruly thinker, who likes to take a critical look at her own prejudices & assumptions - and those of others. She opposes the image that people in poverty are pathetic. She fights against cynicism and always looks at what is possible.
Upcoming events; 21 May ~ Solvency and liquidity in the time of COVID-19 28 May ~ Managing risk as a trader with Garth McKenzie 03 June ~ Pandemic investment scenarios 10 June ~ Margin, gearing & exposure explained 18 June ~ What it means to Invest Globally, Locally Day 56 of lockdown Simon Shares Don't fight the Fed (The Federal Reserve). Markets are in full rally mode and the forward PE of the S&P5- makes it the most expensive in the last decade. During a pandemic and worst US unemployment since the great recession? Bu the point is simple, if the Fed is buying with guns blazing, don't stand in the way, markets will rally higher even if everybody I speak to is bearish. With that in mind, I have bought some TOPSBZ as insurance against another market collapse. It is a put warrant over the Top40, expiry is December and strike is 41,000. So a decent amount of time and about 18% out-the-money. Richemont (JSE code: CFR) raises Euro2billion of cheap debt to go with their almost Euro2.4billion of cash on hand. Now they've always been a conservative company, but they are storing up that balance sheet like crazy. Dischem (JSE code: DCP) results disappoint and buys Baby City for R430million. Solid Santova (JSE code: SNV) results, but to end February. Oil is moving higher as production cus finally start taking effect. Commodities remain strong. Makes no sense unless one assumes a massive post-COVID-19 infrastructure spending boom, and that does make sense. I've been watching countries lifting their lockdowns, gentle but certainly lifting. Germany started lifting in late April (some stores open again) and then more broadly in early May. So far new cases continue to trend down, albeit the early May stats would only start coming in now. But early evidence is that an initial hard lockdown works and then slowly lifting restrictions seems to do the trick. Very early days, but the data is hopefully. Importantly, this is not about removing restrictions, just reducing them. Liberty 2 degrees (JSE code: L2D) update gives great insights into the property sector. April & May saw rental collections around 40%, most malls are now operating at 60% - 70% GLA and foot traffic at 60% pre lockdown levels. All stats are improving during level 4. ZAR at 18 as I record. Video: Getting started in trading Subscribe to our feed here Subscribe or review us in iTunes JSE – The JSE is a registered trademark of the JSE Limited. JSE Direct is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
SNV is taking you on a trip back to 1960 to discuss the hugely influential masterpiece Psycho! In this episode we take a in depth look at the making of, from its birth as a novel, through its casting, its iconic score and titles, to its reputation and legacy on the way that thrillers and horror movies were marketed ever after. So if this current lock-down is driving you mad, then spend a hour with us, because, after all, "we all go a little mad sometimes"
CNV 基因组拷贝数变异 Copy number variation英 [ˌveəriˈeɪʃn] 美 [ˌveriˈeɪʃn]基因组拷贝数变异是基因组变异的一种形式,通常使基因组中大片段的DNA形成非正常的拷贝数量。例如人类正常染色体拷贝数是2,有些染色体区域拷贝数变成1或3,这样,该区域发生拷贝数缺失或增加,位于该区域内的基因表达量也会受到影响。例如SNV:“项项项项”,后代基因变成“项项项象”,这是单独一个碱基的变异;CNV:“项飞项飞项飞”,变为“项飞项飞项飞项飞”,这一组基因的拷贝数由3变为4,这就是拷贝数变异。
CNV 基因组拷贝数变异 Copy number variation英 [ˌveəriˈeɪʃn] 美 [ˌveriˈeɪʃn]基因组拷贝数变异是基因组变异的一种形式,通常使基因组中大片段的DNA形成非正常的拷贝数量。例如人类正常染色体拷贝数是2,有些染色体区域拷贝数变成1或3,这样,该区域发生拷贝数缺失或增加,位于该区域内的基因表达量也会受到影响。例如SNV:“项项项项”,后代基因变成“项项项象”,这是单独一个碱基的变异;CNV:“项飞项飞项飞”,变为“项飞项飞项飞项飞”,这一组基因的拷贝数由3变为4,这就是拷贝数变异。
SNV 单核苷酸位点变异Single nucleotide variant英 [ˈnjuːklɪətaɪd] 美 [ˈnukliəˌtaɪd] / 英 [ˈveəriənt] 美 [ˈveriənt]SNV是指在基因组上由单个核苷酸的替换所引起的变异。人基因组上平均约每1000个核苷酸即可能出现1个单核苷酸多态性的变化,其中有些单核苷酸多态性可能与疾病有关,但可能大多数与疾病无关。在研究癌症基因组变异时,相对于正常组织,癌症中特异的单核苷酸变异是一种体细胞突变,称做SNV。SNP是单核苷酸多态性,也就是说某个位点可以是a,也可以是g,是正常的群体现象;而SNV一般用在疾病里,比如父母都没病,下一代中突然出现某个位点突变,强调该位点突变致病,强调的是突变现象。
SNV 单核苷酸位点变异Single nucleotide variant英 [ˈnjuːklɪətaɪd] 美 [ˈnukliəˌtaɪd] / 英 [ˈveəriənt] 美 [ˈveriənt]SNV是指在基因组上由单个核苷酸的替换所引起的变异。人基因组上平均约每1000个核苷酸即可能出现1个单核苷酸多态性的变化,其中有些单核苷酸多态性可能与疾病有关,但可能大多数与疾病无关。在研究癌症基因组变异时,相对于正常组织,癌症中特异的单核苷酸变异是一种体细胞突变,称做SNV。SNP是单核苷酸多态性,也就是说某个位点可以是a,也可以是g,是正常的群体现象;而SNV一般用在疾病里,比如父母都没病,下一代中突然出现某个位点突变,强调该位点突变致病,强调的是突变现象。
SNV 单核苷酸位点变异Single nucleotide variant英 [ˈnjuːklɪətaɪd] 美 [ˈnukliəˌtaɪd] / 英 [ˈveəriənt] 美 [ˈveriənt]SNV是指在基因组上由单个核苷酸的替换所引起的变异。人基因组上平均约每1000个核苷酸即可能出现1个单核苷酸多态性的变化,其中有些单核苷酸多态性可能与疾病有关,但可能大多数与疾病无关。在研究癌症基因组变异时,相对于正常组织,癌症中特异的单核苷酸变异是一种体细胞突变,称做SNV。SNP是单核苷酸多态性,也就是说某个位点可以是a,也可以是g,是正常的群体现象;而SNV一般用在疾病里,比如父母都没病,下一代中突然出现某个位点突变,强调该位点突变致病,强调的是突变现象。
The guys are joined by Erik Dennison of Orlando's best alternative rock program to discuss the 1986 soundtrack "Pretty in Pink." Plenty of other topics discussed including Corvette Summer, Hannah Harber and the Lionhearts Album Release Party, Catherine Wheel, the Church, being left of center, Y&T posters, the Rave-Ups and, of course, John Hughes. Catch Erik on Sunday nights on Real Radio 104.1 in Orlando. You can also find him: https://patreon.com/theupsanddowns and https://www.facebook.com/sundaynightvinyl
Simon Shares A green January with financials the winners but 2019 is going to be a wild ride, especially in the lead up to the elections expected in May. Tax-free year end is end February, don't leave it for the last minute if you want money in this tax year ending 28 February. Budget on 20 February we'll see if we get any changes to the annual limits. Clover (JSE code: CLR) is delisting at 2500c. A great price considering it was around 1500c last year. I held this stock for a number fo years as I considered it to have great promise, but it never delivered on that promised so I exited. I have had some questions around two stocks I own, Santova* (JSE code: SNV) and Metro File (JSE code: MFL). Both are under share price pressure and both finding growth hard (latest results were OK, nothing special). The share price decline is a factor of liquidity and small stock sentiment. Right now if I was two sell my holdings in each the share price would fall about 10%, that is not normal. Add to that some large sellers (certainly in Metro File) and prices are under pressure. I am holding. Not selling as I happy with the companies nor buying because I don't see the prices rerating higher any time soon, if anything likely lower. More in the main body of the show. Wild and tax-free. Upcoming events Tax-free investing review, who ate the returns? * I hold ungeared positions. Where's the liquidity? In the past week I have seen three reports that all point to a drying up of liquidity on the JSE. Now sure some has likely moved to A2X, but not any significant amount. Bottom line liquidity has fallen fairly markedly and this has impacts, most notable on share price movements. So where has it gone? Simple, investors are scared. Scared of elections. Sacred of EWC. Scared of an under pressure consumer. Scared of trades wars. Scared of no returns. Sacred of their shadow? So they are buying less leaving us with fewer buyers and sellers have mostly exited sitting on the sidelines with their cash. This whole vanishing liquidity is markedly more acute in the mid and small cap space and it is hurting the stock prices. Even us small private investors hurt the stock as we exit and many are throwing in the towel and selling, pushing prices lower causing more to throw in the towel and sell. This is typical in late stage bear markets (late stage bull markets see extreme high levels of liquidity). So what do we do? Well we double our research and make sure we really do like the stock, and if we do - we hold. You can buy more but I think we're a long way from the end of the liquidity squeeze on the small and mid cap stocks. If you're wanting to buy into this low liquidity, be careful. Place bids in the market and wait to be hit, even cheeky bids lower down will potentially be hit. But don't expect liquidity to return tomorrow, it may - but it may take a while longer. Further bad news for holders of small stocks is that when liquidity returns it'll come into the large cap Top40 stocks first, then eventually filter down to the mid and small. Point is it will return one day, we just don't know which day. As an aside, this impacts JSE earnings as they make money from data, listings and trades. less trades is less income with a fair fixed cost base. Last important point. Liquidity is NOT an issue with Exchange Traded Funds (ETFs) as they have a market maker. The market maker is (supposed) to be consistently in the market either side of fair value with their bids and offers. So we can always get what we want at close to fair value. Subscriber to our feed here Subscribe or review us in iTunes JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
This JSE Direct is proudly brought to you by IG, the specialists in CFD trading and a registered financial services provider. Simon Shares Calgro M3* (JSE code: CGR) results a horror. Sure some is due to the new IFRS, but a lot else hurting them right now and I am selling my last remaining shares having sold the bulk in December 2015 at over 2000c. Santova* (JSE code: SNV) results show stronger Rand hurting, but also very tough trading condition locally. I am not selling here. Horror update from Shoprite* (JSE code: SHP). Some due to negative inflation on products, they say "11,607 items in September remaining cheaper than they were a year ago". That hurts as costs rising. But they also had issues in their Gauteng distribution centre that made for stock issues in stores. Famous Brands* (JSE code: FBR) are a two part story. GBK in the UK remains an absolute mess and they're trying to get reductions on leases, an I assume they tried to sell it and failed. Locally they doing alright considering very tough trading conditions. But that UK deal remains a disaster. Naspers (JSE code NPN) closed Tuesday at R2,370 and is now trading Wednesday up almost 8% at R2,555.00. This is in part thanks to Trump saying maybe they could be friends with China and that boosted Tencent. Also MSCI deciding to not make any major changes to index weighting’s with the plan being to reduce weight of stocks with low voting shares, such as Naspers share we trade on the JSE. Vivo (JSE code: VVO) trading update confirms that the Engen deal is done, albeit without the Democratic Republic of Congo assets. This expands them into eight new countries and adds 225 service stations. But Morocco remains an issue as we await the Kings announcement on regulating the fuel price. That are seeing margin pressure here and it is the biggest market for the company - so it's important and while I like the business I want this sorted first. IG CFD conversations; exposure and leverage explained Understanding the NewFunds Momentum Equity ETF* OUTStanding money with Outvest: What you get when you save Upcoming events 01 November ~ JSE Power Hour: When does the bear market arrive? 08 November ~ Master Technical Analysis with Moxima Gama * I hold ungeared positions. JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
Subscriber to our feed here Subscribe or review us in iTunes Simon Shares ZAR almost 15.50 early Monday morning on Lira rout. Improve to around 14.10 but now back at 14.60. Chart of the Top40 shows our market been moving sideways since February between 49,000 and 52,000. fairly small range that has made ALSI futures trend trading hard, very hard. [caption id="attachment_8270" align="aligncenter" width="1080"] Top40 going nowhere for last six months[/caption]Tencent (Hong Kong code: 0700) results saw revenue growing ahead of expectations up 39% but profit only up 25% (YoY figures for half year) and Naspers (JSE code: NPN) is off 6.5% (after being down some 10%) and Top40 -2.7%. Esor (JSE code: ESR) goes into business rescue, so now we have two construction stocks in business rescue (Basil Read the other) with some looking very vulnerable and a number of others already gone. This sector remains a horror story. Pembury (JSE code: PEM) finally issue a trading update, months late, and it is a horror show. Stay away, well when it is unsuspended, stay away. Upcoming events 23 August ~ JSE Power Hour: Three Ramaphosa Rally Recovery Stocks 30 August ~ JSE Power Hour: Practical trading setups and rules 06 September ~ JSE Power Hour: Structuring your investment portfolio When to buy more What are some triggers to buy more of a stock? And how often? I am finding this hard especially once a stock has run a bit. — Daniele Ferreira (@daniele_xyz) August 9, 2018 I run a few portfolios. ETF only, I buy monthly and every March I full up my tax-free and buy in one block. No timing considered. Lazy ETF, weekly charts trading ETFs using technical analysis. Sign up here. Long-term till death do us part portfolio. I use historic PE over last seven years buying when forward PE is below seven year average PE. Details here. Second tier portfolio. This is designed for small and mid cap stocks and this is where I want to focus today. Firstly I find the stock. Quality is important as is growth prospects and I am not looking for 'hot' stocks or sectors. Boring with great potential and low current valuations with a potential holding period of a year to a decade. Using Santova* (JSE code: SNV) as my example. Non-asset based logistics company with their own software based in Durban. Always been very well run as witnessed by results and strong steady growth, both organic and by acquisition. When I fist found it the stock was trading on a PE of around 5x with HEPS for the latest financial year being around 18c (price was 90c) and dividend of 2.5c. I ask myself how easy to double that HEPS in 3-5 years? That requires growth in HEPS of some 15%-25% growth a year. For Santova, very easy. Then I ask what a fair PE should be for this sort of stock? In the case of a logistics company I feel around 13x is fair with wild being 20x. So if HEPS doubles (share price doubles) and PE moves to 13x from current 5x share price goes up another 160%. This takes a 90c stock to around 335c in 3-5 years. Maths all adds up and I buy and wait. Often a very long wait hence I like a dividend to pay me while waiting. HEPS growth comes in and slowly the PE starts to improve and HEPS is 44c for 2018 financial year while PE is now 9.7x and share price is 435c. Do I add more? Well I do the same math again. Can earnings double in next 3-5 years (I think it can, meaning HEPS of 90c). Has PE got space to expand? Yes I still think a 13x PE is fair which targets a share price of some 1170c. Now a few extra thoughts. Firstly a fair PE here is 13x, but a wildly crazy PE is possible and could be 20x (50% of fair target PE). That would add another 50% potential price growth (share then 1755c). But I would only be adding to the position with the current PE well below the fair target (13x) in this case, ideally current PE at least a third below my fair PE, so around 9x. As important is the question about the actual business. Has it delivered? Does it continue to offer great promise? In other words, does the story from when I initially entered remain in force? As the story and price continue to keep playing out I keep on holding and adding. A last point. What will trigger the stock to move and rerate higher? Sure HEPS increases helps but the PE can stay stuck forever and I need both HEPS and PE to increase. hence I especially like stocks that pay a dividend as this pays me while holding and waiting. * I hold ungeared positions. JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
ATTN: This week we have a guest host - CDT’s Director of Surveillance & Security, Greg Nojeim. Greg sits down with Dr. Thorsten Wetzling, the head of research for the German think tank, Stiftung Neue Verantwortung (SNV). Greg and Thorsten have a fascinating conversation about government surveillance practices in the US and in countries across Europe, with Thorsten currently researching the democratization and professionalization of intelligence governance in Germany and Europe. More on SNV: https://www.stiftung-nv.de/ More on Dr. Thorsten Wetzling: https://twitter.com/twetzling More on Greg Nojeim: https://cdt.org/about/staff/greg-nojeim/ More on our host, Brian: bit.ly/cdtbrian Attribution: sounds used from Psykophobia, Taira Komori, BenKoning, Zabuhailo, bloomypetal, guitarguy1985, bmusic92, and offthesky of freesound.org.
In this episode I’m joined by Chang Xu. Chang is a senior biostatistician at QIAGEN and an author of smCounter2, a low-frequency somatic variant caller. To distinguish rare somatic mutations from sequencing errors, smCounter2 relies on unique molecular identifiers, or UMIs, which help identify multiple reads resulting from the same physical DNA fragment. Chang explains what UMIs are, why they are useful, and how smCounter2 and other tools in this space use UMIs to detect low-frequency variants. Links: smCounter2 preprint smCounter2 github repository smCounter publication Review of somatic SNV callers
Subscriber to our feed here Sign up for email alerts as a new show goes live Subscribe or review us in iTunes. Simon Shares So a friend has a business that has been beset by fraud and is now bankrupt and is trying to find some new investors. They have no financial statements to show you and no real idea how bankrupt the company is or how bad the fraud was. Do you invest? So why scramble for busted JSE stocks? Thanks to Kristia van Heerden for the analogy. Libstar (JSE code: LBR) has listed on the JSE. The listing price was right at the bottom of the range at 1250c and opening trade was around 1200c and expensive. Historic PE is apparently around 26x and sub 20x is the maximum to pay, so 900c - 950c. Personally I am not looking to buy. Long4Life* (JSE code: L4L) publish their first results and pay a dividend. The dividend is odd as they on a buying spree so why pay out cash? R1,7bn cash = about third market cap, HEPS 30c so on non cash market cap = PE of some 12x which is fair (compared to some it frankly deeply cheap). Decent Santova* (JSE code: SNV) trading update, especially considering stronger Rand hurting with majority of earnings from offshore. Back in March Naspers (JSE code NPN) sold US$9.8billion worth on Tencent shares and has now sold its Flipcart stake for US$2.2billion. That's a US$12billion (R150billion) pile of cash. Trader1137 on Twitter suggests maybe they'll use it to buy back some shares, would be about 10% of market cap. The Berkshire Hathaway AGM was on Saturday and the audio is here. Upcoming events; Fat Wallet 100th celebration JSE Power Hour: How to profit from SA mining JSE Power Hour: How to identify quality stocks * I hold ungeared positions. Fight the FOMO Fear of missing out. Man this used to kill me when I started out in markets. It's a true killer as it makes us do irrational things. Pause for a moment, we have say 400 stocks listed on the JSE, your odds of picking the top performer over the next ten years is 0.25%. You're pretty much guaranteed to miss out. Globally 100,000 stocks so 0.001% chance. Thing is hype and higher prices make us scared. Scared we picked the wrong stock. Scared we're missing out of becoming fabulously wealthy. We need the courage of our convictions and perhaps more importantly the courage to be wrong, often. FOMO will make us do stupid things. We'll jump in with no real research. We'll jump in with no exit plan. We'll jump in at far to rich valuations. Forgot about the flyers and focus on your plan. What are you investing for and how long is your investment horizon. Find quality stocks at good prices that meet your requirements. And if you find yourself suffering from FOMO remove yourself from the market (like over a weekend or on a internet free holiday) do solid research on the stock. Find the nay sayers and see what the counter argument is and try construct a real evidence based plan and a price you think is a fair one to pay. There is another angle of FOMO I want to touch on as well. When you're in the stock (or crypto or whatever) and now feel you need to convince everybody else that they're missing out. Sure they may be, but truthfully they may have done their own research and decided it is not for them and you could both be right (different strokes for different folks). Not everything is for everybody. But more importantly is that assets need people to be missing out, that's how they go higher. For example Buffett was very late to Apple (Nasdaq code: AAPL) only building a stake in the last 18 months, a stake that is now over 5% of the company. If he'd bought back in say 2008 or 1998 he would not have been a large buyer over the last 18 months and make no mistake, his large buying, and the news of his stake, has sent the price higher. You need late comers. If everybody is in on day one then who pushes the price higher on day two? Taking it a step further, the market needs disagreement otherwise nothing would happen. So don't hate on people who don't love your investments. See them as potential future price drivers. JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
The SNV boys are feeling lazy. GUH! So we got another MGV episode! Call it a valentine's special? Anyway, Shaun Hayes (The Whiparound podcast) chats about the badass vampire flick from Kathryn Bigelow! Check out the Whiparound podcast on iTunes. Then follow them on Instagram, Twitter, and Facebook! www.thewhiparoundpodcast.com Dir. Kathryn Bigelow, 1987. Starring Lance Henrickson, Bill Paxton, Jenny Wright, and Adrian Pasdar. TopgallantRadio.com - Radio for sailors
Simon Shares Just two weeks ago I was moaning about a sideways market going nowhere, now we have eight green days in a row with local markets joining much of the world at all time highs. Famous Brands* (JSE code: FBR) trading update was bleak, very bleak. Interest costs we expected, they suggest SA doing well enough. But UK losing money after paying some R2billion is a shocker. PPC (JSE code: PPC) has doubled in price, remember I said wait for doubling and then buy. So heres your entry. Santova* (JSE code: SNV) comes out with very good trading update considering ZAR strength during the period. List of all listed ETFs ranked by their TERs. A great list from Kristia. Up coming events; FX – Wealth Creator or Poverty stamp The Traders Life: The tools * I hold ungeared positions. When to short shares A recent flurry of emails from people shorting stocks and getting burnt. In particular shorts on Capitec*, Naspers and Kumba. A side note that emailing me is a form of confirmation bias as the emailers wanted me to essentially confirm they were right and the market was wrong. First rule is don't. Second rule is don't short on fundamentals. Short on price action, if you want coupled with fundamentals. But don't just decide a share is expensive so now it must go down, it can get way more expensive. Subscriber to our feed here Sign up for email alerts as a new show goes live Subscribe or review us in iTunes. JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
Simon Shares Market going nowhere, I take a week off and it literally goes sideways in tight range. Capitec* (JSE code: CPI) results saw HEPS up 17% (trading statement said 15%-18%, they always come in near top of range). Lots of wow numbers; 9.2million active clients and cost-to-income ratio at 36%. The disputed arrears coverage ratio is back at 237% after concerns about it decreasing a year ago. Discovery* (JSE code: DSY) results solid with lost of spending on the future. Still my favourite share I own in terms of potential and I happy to add below R156. Richemont* (JSE code: CFR) trading update shows they turned the corner re nasty watch sales that resulted in them having to buy back watches. Stock trading up at all time highs above R120. My buy price is R118. Santova* (JSE code: SNV) nice clean deal buying out a 25% silent partner from their Australian operation at decent price. Gives immediate extra AUD earnings. New Ashburton World ETF Up coming events; The Traders Life: The money with IG and Simon Brown Buying when the Markets are at all-time Highs FX vs Shares – Wealth Creator or Poverty stamp * I hold ungeared positions. Trading time frames The first question no new trader asks is which time frame should they be trading in. Typically one starts looking at daily charts but quickly drops to shorter time frames because we want the rush that comes from each trade and we get more at shorter time frames. Yes trades happen in all time frames, but it's our ability to manage and profit from them. But truthfully can most people manage an intra-day time frame unless this is all they do? Markets is pretty much my life and an hourly chart is still tricky for me as I miss some entries (stops are automated so that no problem). Shorter time frames; Are also more noisy, Require quicker responses Means shorter trade duration, smaller profit per trade but same costs Forget about getting a rush from trading and find a time frame that works for you and potentially use multiple time frames. Start with a weekly chart, if you get a tigger wait for it to confirm in the daily chart. Now if you not using technicals but more about price then tie frames become less of an issue, but you're then having to watch the market consistently hence no other day job or trade at night. We Get Mail I started buying ETF's about 4 months ago. I purchase through on line trading. It appears however that prices are manipulated to keep them within a band. I have been seeing signs of this across all ETF's – some more than others. Last traded prices are impossible to buy at due to the artificial bid volume/price. What makes it even more obvious is often the identical bid / offer volumes. Subscriber to our feed here Sign up for email alerts as a new show goes live Subscribe or review us in iTunes. JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
Are we Brazilian? Are we Brazilian? Simon Shares Metrofile* (JSE code: MFL) 1million shares on offer at 500c. Subtle? Dis-Chem (JSE code: DCP), like everybody else I did not get in the private placement and I am not looking to buy in the open market. Santova* (JSE code: SNV) getting hit. I hold and continue to hold, not buying any more as I have plenty. Twelve month low is 320c on 25 November 2015, looks like we could get back to that level soon enough. Woolies* (JSE code: WHL) saw massive volume on Tuesday, R1.3billion which is 2x - 3x normal value traded. Tongaat* (JSE code: TON) up at R130, nice but I hadn't finished buy below R120. Not buying up at R130 at the moment, albeit target is likely R150-R180 over next 6-12 months. Let's see if we get some weakness. I been digging into Stor-Age Property (JSE code: SSS) as a possible investment. Thus far not excited by what I see. * I hold ungeared positions. Up coming events; Trading Master Class: Tuesday 6th at 6.00pm - Lazy trading indices and FX. JSE Power Hour: Thursday 8th at 5.30pm - Position your portfolio for 2017 Are we the next Brazil? Since their first junk downgrade in September 2015 the Brasil Sao Paulo Stock Exchange Index (IBOV) is up some 50% while the Brazilian Real has strengthened about 20% against the USD. Could we follow the same after a downgrade to junk? JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
Simon Shares Santova (JSE code: SNV) released results that had some dodge workings with the results. Last year they had some abnormal items in their HEPS that they were more than happy to accept. This year they're saying, no take those out to compare against this year as we didn't have the abnormal profits. Well hang on, you can't have it both ways. Either you include and compare or you don't. This is why I always only use diluted HEPS, none of this normalised HEPS nonsense. That all said I hold the stock and am happy. The indices will be adjusting on 21 December with AngloGold Ashanti (JSE code: ANG) exiting the Top40 and that means no gold stocks left in the index for the first time ever. The gold industry is dying locally and has been for a while and this really just confirms that slow death spiral. MTN (JSE code: MTN) has seen their fine reduced to USD3.2billion. A good reduction but still a massive number. The company also announced a series of "new operating structure and senior management changes" to prevent another fine happen. Frankly too late and also not as easy as just shifting some managers, this is about culture and that's deep rooted. I remain a happy non shareholder having sold when the news first broke. We updated the momentum portfolio ad are proposing some changes. Check the video out here and give us your feedback on the changes. Join us on 7 December for the last JSE Power Hour of the year at the JSE. Topic is 'positioning your portfolio for 2016' and being the last function of the year we'll have drinks afterward and we've invited all the speakers from the year so you can mingle and ask questions of them. Year end portfolio review Do your trading systems need tweaking? What have your returns been? What stocks are you keeping or looking to add? Has your portfolio seen any style drift? We Get Mail Derek Please could you let me know which two ETFs you chose for your initial investment and also which online investment platform you used? Eben Please explain how exchange rate fluctuations affect the DBX-Trackers ETFs that I buy/sell on the JSE. ====== Subscriber to our feed here or sign up for email alerts as a new show goes live or subscribe in iTunes. JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
Simon Brown thoughts and portfolio restructuring Selling OML, buying SNV and DSY. the why's and why nots (especially why not GND). Find the portfolio here. Maya Fisher-French - Personal Finance Columnist Author of best selling Maya on Money, implement your money plan. She also runs the website MayaOnMoney.co.za ======================= Subscriber to our feed here or sign up for email alerts as a new show goes live or subscribe in iTunes. JSE – The JSE is a registered trademark of the JSE Limited. JSEDirect is an independent broadcast and is not endorsed or affiliated with, nor has it been authorised, or otherwise approved by JSE Limited. The views expressed in this programme are solely those of the presenter, and do not necessarily reflect the views of JSE Limited.
This week on On Your Mind: It’s an OYM blast from the past with this week’s special-release, archived episode! This episode starts out with a well-deserved congratulation to our very own Liam, for acing his PhD candidacy exam. Now he’s formally allowed to do more work for no change in pay! We also talk about how frustrating it can be when your experiments don’t work and how nerve wracking it is waiting for a funding decision. This is the first (and hopefully last) episode where the “Kath-eter of science” makes an appearance and then it’s onto this week’s paper. It’s called “Detection of Clinically Relevant Genetic Variants in Autism Spectrum Disorder by Whole-Genome Sequencing” by Jiang et al. doi:10.1016/j.ajhg.2013.06.012 This paper brings up some nostalgic flash-backs from Kat, who used to work in ASD research before taking the leap into grad school. Autism spectrum disorders affect 1 in 88 children and are defined by deficits in social skills, communication and repetitive and restrictive interests. Genome-wide association studies (GWAS) have identified genetic polymorphisms that contribute to the risk of ASD but these are common mutations that can’t explain the whole genetic landscape of the disease. This week’s paper uses whole genome sequencing (for a video tutorial: http://www.youtube.com/watch?v=Rzmm57udYdk ) to identify new, rare mutations that are found in 32 children with ASD. These include single nucleotide changes (SNP or SNV), and larger alterations to the genetic sequence (indels and CNVs). The authors attempt to prioritize future medical interventions and follow up for children based on their genetic findings. Of course, this leads us to a rather epistemological discussion on personalized genomics and the pros and cons of putting disorders on a spectrum in the first place. Finally, this week wraps up with a debate about predicting the impact of your research inspired by this article in Science. (http://www.sciencemag.org/content/340/6138/1265.full.pdf)
San Lucas 2:1-20 (Reina-Valera 1960) 1 Aconteció en aquellos días, que se promulgó un edicto de parte de Augusto César, que todo el mundo fuese empadronado. 2 Este primer censo se hizo siendo Cirenio gobernador de Siria. 3 E iban todos para ser empadronados, cada uno a su ciudad. 4 Y José subió de Galilea, de la ciudad de Nazaret, a Judea, a la ciudad de David, que se llama Belén, por cuanto era de la casa y familia de David; 5 para ser empadronado con María su mujer, desposada con él, la cual estaba encinta. 6 Y aconteció que estando ellos allí, se cumplieron los días de su alumbramiento. 7 Y dio a luz a su hijo primogénito, y lo envolvió en pañales, y lo acostó en un pesebre, porque no había lugar para ellos en el mesón. 8 Había pastores en la misma región, que velaban y guardaban las vigilias de la noche sobre su rebaño. 9 Y he aquí, se les presentó un ángel del Señor, y la gloria del Señor los rodeó de resplandor; y tuvieron gran temor. 10 Pero el ángel les dijo: No temáis; porque he aquí os doy nuevas de gran gozo, que será para todo el pueblo: 11 que os ha nacido hoy, en la ciudad de David, un Salvador, que es CRISTO el Señor. 12 Esto os servirá de señal: Hallaréis al niño envuelto en pañales, acostado en un pesebre. 13 Y repentinamente apareció con el ángel una multitud de las huestes celestiales, que alababan a Dios, y decían: 14 !!Gloria a Dios en las alturas, Y en la tierra paz, buena voluntad para con los hombres! m 15 Sucedió que cuando los ángeles se fueron de ellos al cielo, los pastores se dijeron unos a otros: Pasemos, pues, hasta Belén, y veamos esto que ha sucedido, y que el Señor nos ha manifestado. 16 Vinieron, pues, apresuradamente, y hallaron a María y a José, y al niño acostado en el pesebre. 17 Y al verlo, dieron a conocer lo que se les había dicho acerca del niño. 18 Y todos los que oyeron, se maravillaron de lo que los pastores les decían. 19 Pero María guardaba todas estas cosas, meditándolas en su corazón. 20 Y volvieron los pastores glorificando y alabando a Dios por todas las cosas que habían oído y visto, como se les había dicho.
San Lucas 2:1-20 (Reina-Valera 1960) 1 Aconteció en aquellos días, que se promulgó un edicto de parte de Augusto César, que todo el mundo fuese empadronado. 2 Este primer censo se hizo siendo Cirenio gobernador de Siria. 3 E iban todos para ser empadronados, cada uno a su ciudad. 4 Y José subió de Galilea, de la ciudad de Nazaret, a Judea, a la ciudad de David, que se llama Belén, por cuanto era de la casa y familia de David; 5 para ser empadronado con María su mujer, desposada con él, la cual estaba encinta. 6 Y aconteció que estando ellos allí, se cumplieron los días de su alumbramiento. 7 Y dio a luz a su hijo primogénito, y lo envolvió en pañales, y lo acostó en un pesebre, porque no había lugar para ellos en el mesón. 8 Había pastores en la misma región, que velaban y guardaban las vigilias de la noche sobre su rebaño. 9 Y he aquí, se les presentó un ángel del Señor, y la gloria del Señor los rodeó de resplandor; y tuvieron gran temor. 10 Pero el ángel les dijo: No temáis; porque he aquí os doy nuevas de gran gozo, que será para todo el pueblo: 11 que os ha nacido hoy, en la ciudad de David, un Salvador, que es CRISTO el Señor. 12 Esto os servirá de señal: Hallaréis al niño envuelto en pañales, acostado en un pesebre. 13 Y repentinamente apareció con el ángel una multitud de las huestes celestiales, que alababan a Dios, y decían: 14 !!Gloria a Dios en las alturas, Y en la tierra paz, buena voluntad para con los hombres! m 15 Sucedió que cuando los ángeles se fueron de ellos al cielo, los pastores se dijeron unos a otros: Pasemos, pues, hasta Belén, y veamos esto que ha sucedido, y que el Señor nos ha manifestado. 16 Vinieron, pues, apresuradamente, y hallaron a María y a José, y al niño acostado en el pesebre. 17 Y al verlo, dieron a conocer lo que se les había dicho acerca del niño. 18 Y todos los que oyeron, se maravillaron de lo que los pastores les decían. 19 Pero María guardaba todas estas cosas, meditándolas en su corazón. 20 Y volvieron los pastores glorificando y alabando a Dios por todas las cosas que habían oído y visto, como se les había dicho.