Podcasts about organisms

What makes Lyme disease resolve quickly in some people but turn into a life-altering chronic illness in others? In this episode, world-leading immunologist Dr. Michal “Mikki” Tal, Principal Scientist at MIT, explains what her team is discovering through the MAESTRO Study — the largest clinical research project in MIT's history and the first of its kind to include real Lyme patients in a multi-system biological analysis. Dr. Tal's work sits at the intersection of immunology, bioengineering, and women's health, uncovering how infections like Lyme and COVID can cause persistent inflammation, immune miscommunication, and hormonal imbalance. Through MAESTRO, she's mapping how recovery breaks down — and what can be done to predict, prevent, and ultimately reverse chronic illness.

Why are there so many Big Tech monopolies? And perhaps more importantly, should anything be done to stop them? In the final installment of this series, we talk to former Facebook insider Brian Amerige to learn about the inner workings of Silicon Valley’s social media behemoth.Support the show: https://redpilledamerica.com/support/See omnystudio.com/listener for privacy information.

Why are there so many Big Tech monopolies? In Part Two, we continue our remarkable journey by talking to author and visionary Howard Bloom about a natural phenomenon almost completely ignored by the science community. Episode powered by Ruff Greens and The Licorice Guy. The Virtual Organism (Part Three) airs Thursday, February 19th, 2026. Support the show: https://redpilledamerica.com/support/See omnystudio.com/listener for privacy information.

What if DNA could be edited as easily as software? What if we could delete disease, redesign organisms, and eventually rewrite ourselves? In this episode, Adrian Woolfson joins host Güneş Taylor to discuss his book, On the Future of Species. As artificial intelligence fuses with synthetic biology, Woolfson argues that we are beginning to decode the grammar of the genome - learning not just to read life, but to write it. Today, scientists are still in the scribbling phase, editing microbes and viruses. Tomorrow, we may design entirely new organisms or resurrect lost ones. Evolution would no longer be destiny. It would be a choice. But who gets to choose? And what happens to ecosystems, and human nature itself when genomes become editable? If you'd like to become a Member and get access to all our full conversations, plus all of our Members-only content, just visit intelligencesquared.com/membership to find out more. For £4.99 per month you'll also receive: - Full-length and ad-free Intelligence Squared episodes, wherever you get your podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series - 15% discount on livestreams and in-person tickets for all Intelligence Squared events  ...  Or Subscribe on Apple for £4.99: - Full-length and ad-free Intelligence Squared podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series … Already a subscriber? Thank you for supporting our mission to foster honest debate and compelling conversations! Visit intelligencesquared.com to explore all your benefits including ad-free podcasts, exclusive bonus content and early access. … Subscribe to our newsletter here to hear about our latest events, discounts and much more. https://www.intelligencesquared.com/newsletter-signup/ Learn more about your ad choices. Visit podcastchoices.com/adchoices Learn more about your ad choices. Visit podcastchoices.com/adchoices

Why are there so many Big Tech monopolies, and should anything be done to stop them? To find the answer, in part one of this three-part series, we tell the untold origin story of YouTube. Along the way, we speak to two of the founders of pioneering video hosting service Vimeo, Jake Lodwick & Josh Abramson – the team that changed the face of social media. Episode powered by Ruff Greens and The Licorice Guy. The Virtual Organism (Part Two) airs Wednesday, February 18th, 2026. Support the show: https://redpilledamerica.com/support/See omnystudio.com/listener for privacy information.

What is consciousness — and how should biology explain it?In this second conversation with Professor Kevin Mitchell, we examine whether consciousness can be fully accounted for within physics alone — or whether biological organization introduces new levels of explanation.Mitchell develops a non-reductive naturalist framework in which organisms are genuine agents, higher-level causal structures matter, and subjectivity cannot be ignored in any adequate theory of mind.We explore:• What needs explaining when we talk about consciousness• The limits and strengths of physicalist reduction• Weak vs strong emergence• Biological organization as a causal framework• Downward causation and levels of explanation• Organisms as agents rather than passive mechanisms• The role of the conscious subject• Mental causation and explanatory gaps• Teleology in evolutionary systems• Whether artificial systems could instantiate subjectivityTIMESTAMPS:(0:00) – Introduction(0:32) – Kevin's Approach to Consciousness(1:12) – Consciousness and the Requirement of a Subject(3:59) – AI, Functionalism, & Biological Naturalism(7:37) – Embodiment, In-Mindedness & Experiential Bedrock(11:19) – Control Architectures, Attention, and Illusionism(15:21) – Selfhood Perspectives: Jennings, Graziano & Humphrey(19:08) – Temporal Continuity & Brains as Semantic Engines(23:03) – Top-Down Causation and Dynamical Self(27:00) – Levels of Selfhood & Autobiographical Continuity(30:43) – Neuroscience, Psychiatry & Emergent Mental Phenomena(38:15) – Altered Subjectivity & Embodiment in Injury(44:06) – Life, Consciousness, and AI Agents(50:23) – Philosophy, Science & Indeterminacy(56:28) – Neural Noise, Decision-Making & Agency(1:10:48) – Reasons, Choices & Moral Development(1:20:43) – Emergence, Transcendence & First-Person Neuroscience(1:26:50) – Kantian Structures & Perception(1:30:35) – Defining Mind & Relational Perspectives(1:34:52) – Final ThoughtsEPISODE LINKS:- Kevin's Round 1: https://youtu.be/UdlkYGbuD7Q- Kevin's Website: https://www.kjmitchell.com/- Kevin's Blog: http://www.wiringthebrain.com- Kevin's Books: https://tinyurl.com/2p9yjzxr- Kevin's Publications: https://tinyurl.com/mskdpvce- Kevin's Twitter: https://twitter.com/wiringthebrain- Consciousness needs a subject:https://philpapers.org/rec/MITCNA-2- Reframing the free will debate: the universe is not deterministic:https://link.springer.com/article/10.1007/s11229-026-05455-7- Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience:https://onlinelibrary.wiley.com/doi/abs/10.1111/ejn.70064- Undetermined: Free will in real time and through time:https://dialnet.unirioja.es/servlet/articulo?codigo=10358095- The origins of meaning - from pragmatic control signals to semantic representations:https://osf.io/preprints/psyarxiv/dfkrvCONNECT:- Website: https://mindbodysolution.org - YouTube: https://youtube.com/@mindbodysolution- Podcast: https://creators.spotify.com/pod/show/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu- Website: https://tevinnaidu.com=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.

Geoffrey West didn't set out to explain work. He was a physicist trying to understand why living things grow, age, and die. But when his questions expanded into biology, cities, and organizations, they offered a way to think about why growth changes how organizations behave and why success often brings new constraints. In this episode, Dart and Geoffrey discuss why work feels different as organizations scale, why cities keep renewing themselves while companies tend to burn out, and what these hidden constraints mean for the people doing the work.Geoffrey West is a British theoretical physicist and Distinguished Professor at the Santa Fe Institute. He is a former president of the Institute and the author of Scale, which explores how size shapes growth, innovation, and lifespan across living and social systems.In this episode, Dart and Geoffrey discuss:- Why work changes as organizations grow- How simple scaling laws shape complex systems- Why larger animals live longer- Why companies die younger than cities- How scale speeds up innovation- Why bureaucracy grows with success- How innovation gets crowded out over time- Why cities tolerate difference better than firms- What keeps work alive inside organizations- And other topics…Geoffrey West is a British theoretical physicist and Distinguished Professor at the Santa Fe Institute, where he previously served as president. Earlier in his career, he led the high-energy physics group at Los Alamos National Laboratory and held faculty positions at Stanford University. His research focuses on universal scaling laws in biology, cities, and social systems, examining how size shapes growth, innovation, and lifespan. He is the author of Scale.Resources Mentioned:Scale: The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies, by Geoffrey West: https://www.amazon.com/Scale-Universal-Innovation-Sustainability-Organisms/dp/014311090XConnect with Geoffrey:Official website: https://www.geoffreywest.com/Work with Dart:Dart is the CEO and co-founder of the work design firm 11fold. Build work that makes employees feel alive, connected to their work, and focused on what's most important to the business. Book a call at 11fold.com.

Thomas Halliday concludes with the climate-driven Ordovician mass extinction, the Cambrian explosion of modern animal body plans in China featuring predators like Omnidens, and the Ediacaran era's strange soft-bodied organisms preceding complex life.

A bold reimagining of life that bridges science, philosophy, cybernetics, and the complexities of biological existence The Organism Is a Theory: Giuseppe Longo on Biology, Mathematics, and AI (Giuseppe Longo and Adam Nocek, 2026) is an intriguing synthesis of decades of interdisciplinary research by eminent mathematician and biological scientist Giuseppe Longo. A unique collaboration between Longo and philosopher of technology Adam Nocek, the volume confronts foundational issues in the history of mathematics, computer science, physics, and theoretical biology. Challenging conventional approaches that apply computational and formalist models to the biological world, Longo reveals how the limitations of these models hinder the understanding of organismic complexity, development, and evolution. Through a critique of dominant scientific paradigms, he emphasizes the need for a new biological theory that accounts for the temporal and spatial intricacies of life. Enhanced by Nocek's comprehensive introduction and a fascinating three-part interview with Longo, The Organism Is a Theory offers a bold rethinking of the biosciences, integrating the work of Alan Turing, Bernhard Riemann, Henri Poincaré, Kurt Gödel, and others into Longo's vision of critical biology. Bridging scientific and philosophical discourses, this book creatively applies insights from mathematics, physics, and computing into the study of the organism to present a new theoretical approach to understanding biological complexity that resists reductive mechanistic and informatic explanations. Retail e-book files for this title are screen-reader friendly with image accompanied by short alt text and/or extended description. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science-technology-and-society

A bold reimagining of life that bridges science, philosophy, cybernetics, and the complexities of biological existence The Organism Is a Theory: Giuseppe Longo on Biology, Mathematics, and AI (Giuseppe Longo and Adam Nocek, 2026) is an intriguing synthesis of decades of interdisciplinary research by eminent mathematician and biological scientist Giuseppe Longo. A unique collaboration between Longo and philosopher of technology Adam Nocek, the volume confronts foundational issues in the history of mathematics, computer science, physics, and theoretical biology. Challenging conventional approaches that apply computational and formalist models to the biological world, Longo reveals how the limitations of these models hinder the understanding of organismic complexity, development, and evolution. Through a critique of dominant scientific paradigms, he emphasizes the need for a new biological theory that accounts for the temporal and spatial intricacies of life. Enhanced by Nocek's comprehensive introduction and a fascinating three-part interview with Longo, The Organism Is a Theory offers a bold rethinking of the biosciences, integrating the work of Alan Turing, Bernhard Riemann, Henri Poincaré, Kurt Gödel, and others into Longo's vision of critical biology. Bridging scientific and philosophical discourses, this book creatively applies insights from mathematics, physics, and computing into the study of the organism to present a new theoretical approach to understanding biological complexity that resists reductive mechanistic and informatic explanations. Retail e-book files for this title are screen-reader friendly with image accompanied by short alt text and/or extended description. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/technology

A bold reimagining of life that bridges science, philosophy, cybernetics, and the complexities of biological existence The Organism Is a Theory: Giuseppe Longo on Biology, Mathematics, and AI (Giuseppe Longo and Adam Nocek, 2026) is an intriguing synthesis of decades of interdisciplinary research by eminent mathematician and biological scientist Giuseppe Longo. A unique collaboration between Longo and philosopher of technology Adam Nocek, the volume confronts foundational issues in the history of mathematics, computer science, physics, and theoretical biology. Challenging conventional approaches that apply computational and formalist models to the biological world, Longo reveals how the limitations of these models hinder the understanding of organismic complexity, development, and evolution. Through a critique of dominant scientific paradigms, he emphasizes the need for a new biological theory that accounts for the temporal and spatial intricacies of life. Enhanced by Nocek's comprehensive introduction and a fascinating three-part interview with Longo, The Organism Is a Theory offers a bold rethinking of the biosciences, integrating the work of Alan Turing, Bernhard Riemann, Henri Poincaré, Kurt Gödel, and others into Longo's vision of critical biology. Bridging scientific and philosophical discourses, this book creatively applies insights from mathematics, physics, and computing into the study of the organism to present a new theoretical approach to understanding biological complexity that resists reductive mechanistic and informatic explanations. Retail e-book files for this title are screen-reader friendly with image accompanied by short alt text and/or extended description. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

A bold reimagining of life that bridges science, philosophy, cybernetics, and the complexities of biological existence The Organism Is a Theory: Giuseppe Longo on Biology, Mathematics, and AI (Giuseppe Longo and Adam Nocek, 2026) is an intriguing synthesis of decades of interdisciplinary research by eminent mathematician and biological scientist Giuseppe Longo. A unique collaboration between Longo and philosopher of technology Adam Nocek, the volume confronts foundational issues in the history of mathematics, computer science, physics, and theoretical biology. Challenging conventional approaches that apply computational and formalist models to the biological world, Longo reveals how the limitations of these models hinder the understanding of organismic complexity, development, and evolution. Through a critique of dominant scientific paradigms, he emphasizes the need for a new biological theory that accounts for the temporal and spatial intricacies of life. Enhanced by Nocek's comprehensive introduction and a fascinating three-part interview with Longo, The Organism Is a Theory offers a bold rethinking of the biosciences, integrating the work of Alan Turing, Bernhard Riemann, Henri Poincaré, Kurt Gödel, and others into Longo's vision of critical biology. Bridging scientific and philosophical discourses, this book creatively applies insights from mathematics, physics, and computing into the study of the organism to present a new theoretical approach to understanding biological complexity that resists reductive mechanistic and informatic explanations. Retail e-book files for this title are screen-reader friendly with image accompanied by short alt text and/or extended description. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

A bold reimagining of life that bridges science, philosophy, cybernetics, and the complexities of biological existence The Organism Is a Theory: Giuseppe Longo on Biology, Mathematics, and AI (Giuseppe Longo and Adam Nocek, 2026) is an intriguing synthesis of decades of interdisciplinary research by eminent mathematician and biological scientist Giuseppe Longo. A unique collaboration between Longo and philosopher of technology Adam Nocek, the volume confronts foundational issues in the history of mathematics, computer science, physics, and theoretical biology. Challenging conventional approaches that apply computational and formalist models to the biological world, Longo reveals how the limitations of these models hinder the understanding of organismic complexity, development, and evolution. Through a critique of dominant scientific paradigms, he emphasizes the need for a new biological theory that accounts for the temporal and spatial intricacies of life. Enhanced by Nocek's comprehensive introduction and a fascinating three-part interview with Longo, The Organism Is a Theory offers a bold rethinking of the biosciences, integrating the work of Alan Turing, Bernhard Riemann, Henri Poincaré, Kurt Gödel, and others into Longo's vision of critical biology. Bridging scientific and philosophical discourses, this book creatively applies insights from mathematics, physics, and computing into the study of the organism to present a new theoretical approach to understanding biological complexity that resists reductive mechanistic and informatic explanations. Retail e-book files for this title are screen-reader friendly with image accompanied by short alt text and/or extended description. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hello Interactors,It's winter. So, as the sun tilts toward the sun (up north) my writing tilts toward the brain. It's when I put on my behavioral geography glasses and try to see the world as a set of loops between bodies and places, perception and movement, constraint and choice. It's hard to do that right now without running into AI. And one thing that keeps nagging at me is how AI is usually described as this super-brain perched in the cloud, or in a machine nearby, thinking on our behalf.That framing inherits an old habit of mind. Since Descartes, we've been tempted by the idea that the “real” mind sits apart from the messy body, steering it from some inner control room. Computer metaphors reinforced the same split by calling the CPU the “brain” of the machine. And now we're extending the metaphor again with AI as the brain of the internet, hovering overhead, crunching data, issuing guidance. An intelligence box directing action at a distance is a tidy picture but it risks making us miss what's actually doing the work. Let's dig into how the brain leverages the loops of people, places, and interfaces we all move through to extend it's richness and reach.GRADIENTS GUIDE WHILE BODIES BALANCEHave you ever hiked or skied in snow or fog and seen the middle distance just in front of you disappear? It takes the world you thought you knew, like ridge lines, tree lines, and the comforting predictable geometry of “just ahead” and reduces it to panic stricken near-field fragments. I've sensed once familiar ski runs become suddenly unfamiliar not because it changed, but because it was no longer accessible to my brain.In these moments, we're all forced to reckon, recalibrate, and (usually) slow down as our senses sharpen. We take note of the slope under our feet and the way the ground shifts. We listen for clues our eyes can't see and notice which direction the wind is blowing, how the light is changing, and how our own heartbeat and breath changes with each calculated risk. We know where we are, but the picture is fuzzy. Our memory only gets us so far. Everything around us becomes this multi-faceted relationship between our body making sense of it all while our brain updates its status moment by moment. The last thing a brain wants is to have its co-dependent limbs fail and risk falling.That experience demonstrates how the world is coupled with us. In world-involving coupling a living system survives through ongoing coordination with the affordances and constraints of its surroundings. In behavioral geography this frames spatial behavior as dynamic, reciprocal coordination between individuals and their environments, rather than just isolated internal cognition.Places actively shape decisions through the physics of the world and all its constraints. Actions, in turn, then reshape those surroundings in ongoing loops. This approach to cognition shifts focus from isolated mental maps to lived, constitutive engagements. It treats the world as a partner in our own competence.Before brains, gradients existed. Living systems navigated heat, cold, salt, sugar, thirst, dark, and light to persist. The first cognitive problems were biophysical. Surviving in a world that constantly disrupted viability relied on basic mechanisms like membrane flows, chemical reactions, and feedback. These primordial loops coupled an organism to a given environment directly. There were not yet any neural intermediaries. These were protozoa drifting toward nutrients or recoiling from toxins. It is in this raw attunement that world-involving coupling emerges.In 1932, physiologist Walter Cannon coined the term “homeostasis” to describe the body's active pursuit of stability amidst environmental pressures. Living systems, whether single-celled or more complex, maintain survival variables within narrow bands. Cells detect changes in these variables, which affect molecular states. Temperature, acidity, pressure, osmosis, and metabolic concentrations all influence reaction rates. Feedback loops alter cell-environment interactions through heat transfer, ion flux, water movement, and gas exchange, ultimately restoring the system to a viable band. Organisms are not passive vessels but actively engage with these detection loops, triggering adjustments like a wilting plant drawing water. Sensing and action are fused operations for persistence.About 600 million years ago, cells in an ancient sea sensed electrical fields or chemical plumes on microbial mats. These pioneering cells formed diffuse nerve nets, evolving into jellyfish and anemones. Simple meshes firing to contract thin membranes in bell-shaped forms, they lacked a brain but coordinated propulsive pulses to keep the organism in bounds or sting prey. Within 10s of millions of years, bilateral animals evolved. Flatworms like planaria emerged with nerve cords laddered along their undersides, thickening toward their tips. These proto-brains sped signal spread across their elongated forms.As vertebrates appear, control becomes more layered. Circuits in the brainstem evolve to coordinate breathing, heart rate, posture, and basic orienting reflexes. The cerebellum emerges to sharpen timing and coordination. Competing actions, drives, and habits become sorted with the help of the basal ganglia. With mammals — and especially primates — the cortex expands. Perception and action become more flexible across situational contexts and with it comes longer-horizon learning, social inference, and planning.But at every milestone, bodies are still constrained and governed by gradients and fields related to gravity, friction, heat, oxygen, hydration, predators, prey, and terrain. The cortex sits on top of these older loops, stretching them in time and recombining them in new ways. Even the most “abstract” human cognition still rides on the same foundation of reflexes and sensorimotor sampling. This is what keeps an organism in operable biochemical ranges while it propels itself through an environment that perpetually pushes and pulls.BOXED BRAINS BEGET BIG BELIEFSThe field of physiology deepened this bio-chemical inquiry through the early 20th century. Physiologist and neurologist Ivan Pavlov revealed how sensory cues could chain to responses through neural rerouting creating conditioned ‘Pavlovian' reflexes. Neurophysiologist Charles Sherrington coined the term “synapse” as he dissected and described them as switches in these loops coupled to the world. Through this inquiry, the autonomic nervous system emerged as a kind of homeostatic controller. Sympathetic surges in the system were found to create fight or flight reactions as our parasympathetic system kicks in to dial us back. This can be seen as a more complex version of the same push-pull of Cannon's original homeostasis.By the mid-20th century, mathematician and philosopher Norbert Wiener, working closely with physiologists and engineers, compared the nervous system to a servomechanism — a self-correcting governor found in engines. He coined the term cybernetics in his 1948 book Cybernetics: Or Control and Communication in the Animal and the Machine where he treated animals and machines as systems that regulate themselves through feedback. He and his collaborators argued this was a form of “purposeful behavior” or goal-directed action — a kind of negative feedback loop that reduces the difference between a current state and a target state. These ideas hardened in engineering fields during wartime as they were used in weapon systems for prediction and control of trajectories by compensating for delay and uncertainty. Cybernetics helped make the physiological regulation of Cannon's biological homeostasis structurally analogous to engineering.This mechanical metaphor sparked a long-standing debate, dating back to Descartes' 17th-century mind-body split. Dualism posited an immaterial mind as a rule-following pilot controlling mechanical flesh. Alan Turing's 1936 paper had already formalized this possibility, presenting a “machine” capable of computing any algorithm. Two decades later, the Dartmouth summer workshop coined “artificial intelligence” and encouraged the idea of engineering minds as programs. Around the same time, Herbert Simon and Allen Newell built early “logic theorist” programs that proved theorems, making intelligence seem like a boxed process involving symbols and reasoning. That lineage hasn't disappeared. This is largely the default engineering posture of AI. Even when the machinery shifts from hand-coded rules to learned statistical patterns, we still talk as if intelligence lives inside a system. AI models claim to “form representations,” “build a world model,” “store knowledge,” “plan,” and “reason.” Contemporary training methods reward this language because they really do produce rich internal states that can be probed, steered, and reused across tasks.Less discussed is the metaphysical shift from “the system has internal structure supporting performance” to “the system contains an inner arena where meaning emerges and is inspected before action.” Daniel Dennett, a philosopher who dismantled this intuition in theories of mind and consciousness, called this picture the “Cartesian theater.” He noticed that scientific explanations often subtly reintroduce the central place where “it all comes together” for an internal witness. Dennett believes this inner stage is a comforting fiction derived from Descartes' split between observer and world. Brain imaging reveals coordinated network activity, but not a literal inner ‘screen' presenting a unified world-model. Many neuroscientists describe cognition as emerging from distributed, parallel, and recurrent processes, sometimes with large-scale integration. Dennett's point is not that internal processing is unreal, but that our language tempts us toward a surreal Cartesian picture in a central place we can't empirically reveal.RESAMPLE, RESTABILIZE, AND RESHAPENeuroscience reveals that perception differs from a camera feeding a private theater. Our eyes rapidly sample information based on our actions, and the brain stabilizes perception during movement. Much visual processing is organized in the service of action, with partially distinct but interacting pathways supporting perceptual report and real-time visuomotor control. This suggests that the brain resembles a system for maintaining a relationship with the world through continuous sampling, correction, and skilled engagement, rather than a world-reconstruction engine.James J. Gibson, the founder of ecological psychology, arrived at a similar conclusion earlier from behavioral and perceptual evidence. He argues that the world provides lawful patterns, regularities constrained by physics and geometry, that guide behavior because they remain stable across changing viewpoints. These patterns are not complete. Organisms make them available by moving, shifting gaze, turning the head, walking, or touching. Perception is an active process of sampling the world.If perception is about staying attuned to lawful structures in the environment, the evolutionary consequence is organisms don't just read the world, they also write it. As organisms became more complex and mobile, they gained the power to reshape the very patterns they depend on. They start cutting paths (pathways worn into grass, game trails beaten into forests), building shelters (bird nests, termite mounds, human dwellings), altering flows of water and heat (beaver dams, termite mounds), and laying chemical trails (ants depositing pheromones).Evolutionary biologists call this niche construction. Organisms modify their environments, which then feed back into selection pressures and development, creating a dynamic cycle where the environment becomes a product of life and a force that shapes it further. As the world guides behavior, behavior reshapes the world, and the remade world trains bodies and brains into new skills and expectations. Over time, these modifications become external organs of coordination, storing information, reducing uncertainty, and channeling action.A worn trail is navigational memory made durable, a nest or mound is a climate-control device that stabilizes temperature and airflow, and a pheromone path is a distributed signal that recruits other ants into collective action and direction. Complexity scientist David Krakauer calls this broader idea of “mind outsourced into engineered matter” exbodiment — where artifacts actively constrain and channel cogntion. In this view, cognitive work is no longer confined to nervous tissue but accomplished through bodies working with worlds they've built.Humans take this to an extreme. Clothing and shelter externalize thermoregulation, fire externalizes digestion and protection, tools externalize force and precision, drugs alter chemistry, writing and calendars externalize memory and timing, and institutions externalize norms and coordination. Much of what we call “human intelligence” is not only in our brains but also distributed across artifacts and practices that have accumulated over generations.Cognitive anthropologist Edwin Hutchins made the point vivid by studying navigation. On a ship, “knowing where you are” is not privately derived nor sealed in a captain's skull. It is a collective achievement through a system of charts, maps, instruments, procedures, language, coordinated roles — an entire ecology of cognition comprised of tools and social organization. Here geography and cognition merge. Orientation is not just mental but enacted in relation to representations that are anchored and socially maintained in our material reality.When I was at Microsoft, I followed the work of sociologist Lucy Suchman who studied human-machine interaction. She arrived at a similar conclusion criticizing the fantasy that action is simply “execution of an internal plan.” Real action, she argues, is situated. It's responsive to unfolding circumstances — often improvisational — and is shaped by context in ways that cannot be fully specified in advance. In other words, if we look for intelligence as a prewritten script inside the head, we will miss how intelligence is often produced when enacted in a world that refuses to hold still.Large language models, at first glance, seem to embody the “internal plan” fantasy. They're sealed systems containing competence in weights and parameters, ready for queries. However, they're closer to Suchman's warning. Trained on vast archives of human writing, LLMs learn statistical regularities in vast continuations of text. When used, they produce a new continuation conditioned on prompts and context. Prompts aren't mere inputs. They're situated actions in human-computer interactions. They set frames, narrow affordances, cue roles, establish constraints, and often iterate in a back-and-forth that resembles Suchman's improvisation with a powerful partner who is also techy and textual.Philosophers Andy Clark and David Chalmers, in their extended mind thesis, claim under certain conditions, external tools can become constitutive parts of cognition when they are reliably integrated into the organism's routines. As we've learned, the boundary of cognition is not always the boundary of skin or skull, it's the boundary of a stable loop.When the fog rolls in and visibility gets low, the boundary of this loop becomes quickly apparent. “The mind's eye” is not that helpful…practically or metaphorically. If anything, the brain wants nothing more than for the body to widen contact with the world. It slows us down, sharpens listening, and increases tactile attention. It calculates different gradient thresholds to measure risk…it might even glance at an external sensing device that is prompting some intervention or improvisation! We are not watching a movie in our head to get through the fog. We are trying to stay oriented in a world that refuses to be fully represented.This is the reframing of intelligence — artificial and otherwise — I wish for. I'd like to see more talk of intelligence being less a coveted individualistic thing hidden inside us and more an achievement of coordinated biophysical, social, infrastructural loops across time. When we mistake a metaphor (“there's a theater in there”) for an ontology (“that's where cognition lives”), we get misled about minds and we get misled about AI. The alternative is not anti-technology. It's conceptual hygiene. Let's start asking where cognition actually happens, what it is made of, and how places — natural and built — participate in making it possible. You know, Interplace — the interaction of people and place. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit interplace.io

On this episode of Small Talk we discuss the 52Toys Xenomorph and all the latest action figure news!

For over a century, neuroscience has assumed that consciousness is generated by the brain.But what if this assumption is wrong?In this episode of Mind-Body Solution, Dr. Tevin Naidu is joined by Professor Edward F. Kelly - co-author of Irreducible Mind, Beyond Physicalism, Consciousness Unbound (and many more) — to examine the empirical and conceptual evidence that consciousness cannot be fully explained by brain activity alone.TIMESTAMPS:00:00 – Introduction: The Limits of Brain-Based Models: Kelly's career, scope of inquiry, and why physicalism fails to account for mind08:55 – First Direct Encounter with Psi Phenomena: Meeting high-performing experimental subjects and abandoning residual skepticism13:45 – Why Physicalism Cannot Accommodate Psi as Facts of Nature: Empirical accumulation forces a worldview shift17:10 – The Cultural Consequences of Reductive Materialism: How mechanistic metaphysics shapes ecological and existential crises21:30 – Irreducible Mind: Strategy and Scope: Why Kelly and colleagues targeted physicalism empirically first29:30 – Extreme Psychophysical Phenomena: Stigmata, maternal impressions, and mind–body influence beyond placebo33:50 – Dissociative Identity Disorder & Multiple Centers of Consciousness: Why unitary brain-mind assumptions break down37:20 – Near-Death Experiences Under Clinical Unconsciousness: Verified perception during anesthesia and cardiac arrest41:05 – Empirical vs Conceptual Failures of Materialism: Why both lines of critique are now unavoidable44:50 – The Need for a Post-Physicalist Theory: Why data alone can't shift science without a new metaphysical framework49:25 – Beyond Physicalism: Surveying Alternative Worldviews: Idealism, dual-aspect monism, panentheism, and mystical traditions55:10 – Whitehead, Process Philosophy & Its Limits: Why mystical experience must be taken seriously as data59:20 – William James, the Subliminal Self & the Pluralistic Universe: Consciousness as layered, expansive, and not brain-produced1:03:35 – Consciousness Unbound: New Empirical Frontiers: Reincarnation cases, precognition, and psychedelic-induced mysticism1:07:45 – Bernardo Kastrup, Analytic Idealism & Survival Debates: Where Kelly agrees—and where he diverges1:11:30 – Physics, Possibility & Reality Beyond Actuality: Quantum foundations, potentiality, and expanded ontology1:15:55 – The New Book: Narrowing to Viable Post-Physicalist Theories: Why process philosophy and organismic biology are converging1:19:20 – Consciousness Below the Brain: Cells, Organisms & Evolution: Why mind may extend deep into life itself1:23:30 – Closing Reflections: Toward an Expanded Science of Mind: What replacing physicalism actually means for humanityEPISODE LINKS:- Ed's Website: https://med.virginia.edu/perceptual-studies/dops-staff/ed-kelly/- Ed's Publications: https://scholar.google.com/citations?user=q42C6BwAAAAJ&hl=en- Ed's Books: https://www.amazon.com/stores/author/B001IU2STWCONNECT:- Website: https://mindbodysolution.org - YouTube: https://youtube.com/@MindBodySolution- Podcast: https://creators.spotify.com/pod/show/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu- Website: https://tevinnaidu.com=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.

Kick off 2026 with a special edition of the Global DJ Broadcast: New Year's Rehab. Markus Schulz takes you on a journey through the sultry, sexy and euphoric moods of the afterhours, blending indie dance, Italian disco-inspired sounds and hypnotic late-night grooves. This standalone mix captures the essence of the early morning hours where music turns introspective, playful, and irresistibly addictive. Perfect for winding down after the celebrations or for embracing the start of a brand-new year.   Tracklist:   01. Hellmuth - Can't Resist 02. The Organism vs. John Summit, HAYLA & Millero - Serotonin Where You Are (Markus Schulz Mashup) 03. John Lord Fonda & Damon Jee vs. Tall Paul - Les Dunes d'Altair de Voodoo Ray (Markus Schulz Mashup) 04. Monococ - Pressure 05. Frankey & Sandrino - Acamar 06. Hellmuth - Stockholm Syndrome 07. Rex the Dog - Change This Pain for Ecstasy 08. David Tort & Kurt Caesar - Clear All Patterns 09. Alessa Khin - Hanami 10. GENESI, Wave Wave & Roland Clarke - Phones Down (Hellmuth Rework) 11. Damon Jee & Demian - Memories 12. Architectural vs. Stylo & Space Motion - Never Be Yours Again, Boy (Markus Schulz Mashup) 13. Ed Ed - The Ellcrys 14. Laurent Garnier - Man with the Red Face 15. Infektion vs. MODEON - Disco Crazy Armor (Markus Schulz Mashup) 16. Kollektiv &Turmstrasse - Stalker: Cold Love 17. Frankie Knuckles presents Director's Cut - Your Love (Director's Cut Signature Mix) 18. Luka Cikic - Floating in Desert 19. Dave Brody - Eclipse (Guy J Remix) 20. Ame, Trikk & Jens Kuross - Don't Waste My Time 21. Empire of the Sun - We Are the People (Adam Sellouk Remix) 22. Eagles & Butterflies - The Trip (Jennifer Cardini & Damon Jee Remix) 23. Deep Dish x Eynka featuring Wrabel - Midnight  

Today we sit with the old questions and let them breathe again, tracing the places where life begins to feel like a presence rather than a computer. Turner walks through the fault lines of modern biology, pointing to the quiet mind-like shimmer in organisms shaping their worlds. The conversation moves slowly, deliberately, as if the universe itself were leaning in to listen. By the end, the idea of agency feels less like a taboo and more like something we've sensed all along.Part 1: https://youtu.be/MOr-FZ_ogTIPATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-showHOMEBREW MUSIC - Check out our new album!Hard Copies (Vinyl): FREE SHIPPING https://demystifysci-shop.fourthwall.com/products/vinyl-lp-secretary-of-nature-everything-is-so-good-hereStreaming:https://secretaryofnature.bandcamp.com/album/everything-is-so-good-here00:00 Go! 00:08:43 – Gene-Centered Evolution Takes Over00:11:10 – McClintock's Discovery Breaks the Mold00:14:19 – Genes as Interpreted Signals, Not Dictators00:18:11 – From Mutationism to Epigenetics00:20:41 – Dawkins and the Selfish Gene Frame00:24:30 – Life Strives for More Than Survival00:27:47 – Culture as a Force in Evolution00:30:28 – Termites and Environmental Inheritance00:32:22 – When Literalism Distorts Science and Religion00:35:22 – Beyond Gould's Magisteria00:39:02 – The Aiming of Organisms00:41:58 – Desire, Agency, and Evolutionary Trajectories00:44:14 – Human Exceptionalism and the Myth of Evolution's End00:47:46 – Cultural Barriers to Integrative Biology00:49:39 – The Transcendence of Materials00:52:10 – Purposeful Behavior in Termite Societies00:55:35 – Preference and Purpose in Termite Architecture00:59:14 – Human Metaphysics and Cognitive Niches01:04:19 – Cracks in the Evolutionary Consensus01:06:39 – Biology as the Bridge Between Facts and Meaning01:08:58 – The Missing Definition of Life01:10:59 – Biology's Identity Crisis01:12:36 – Rethinking Life and the Universe01:15:08 – The Origin of Life Problem01:16:28 – From Chemistry to Cognitive Emergence01:20:27 – Life as a Gradual Flame01:23:13 – Agency as the Heart of Biology01:25:42 – The Scientific Struggle With Agency01:27:04 – Turner's Work on Organisms, Design, and Purpose #consciousness, #agency , #evolution, #originoflife, #emergence, #complexity , #cognition , #purpose , #epigenetics , #philosophy, #meaning, #physicspodcast, #philosophypodcast MERCH: Rock some DemystifySci gear : https://demystifysci-shop.fourthwall.com/AMAZON: Do your shopping through this link: https://amzn.to/3YyoT98DONATE: https://bit.ly/3wkPqaDSUBSTACK: https://substack.com/@UCqV4_7i9h1_V7hY48eZZSLw@demystifysci RSS: https://anchor.fm/s/2be66934/podcast/rssMAILING LIST: https://bit.ly/3v3kz2S SOCIAL: - Discord: https://discord.gg/MJzKT8CQub- Facebook: https://www.facebook.com/groups/DemystifySci- Instagram: https://www.instagram.com/DemystifySci/- Twitter: https://twitter.com/DemystifySciMUSIC: -Shilo Delay: https://g.co/kgs/oty671

Should we view our church as an organism or as an organization? How you define the church will decide how you participate in it. So, let's give some careful thought to how the church should function. We'd love to hear your thoughts and questions. You can reach me at josh@bibledirectionforlife.com.

This is the second lesson in Dr. James Cassidy's Reformed Academy course, The Doctrine of the Church. This lesson covers the following topics: 00:00 The Church Militant and the Church Triumphant 04:51 The Church as Organization and Organism 10:13 Ecumenicity 19:51 The Attributes of the Church: The Church as Holy Register for this free on-demand course on our website to track your progress and assess your understanding through quizzes for each lesson. You will also receive free access to dozens of additional video courses in covenant theology, apologetics, biblical studies, church history, and more: https://reformedacademy.org/course/do... Your donations help us to provide free Reformed resources for students like you worldwide: https://reformedforum.org/donate/ #church #reformed #presbyterian #ecclesiology #reformedtheology

Episode 2720 - Vinnie Tortorich welcomes Dr. Tony Hampton to discuss focusing on policy, advocating for change, use of GLP-1s, and more. https://vinnietortorich.com/2025/11/focusing-on-policy-episode-2720 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Focusing On Policy Dr. Tony Hampton has been a guest on the show several times—he has a long history of advocating in the low-carb space. (2:00) Being policy-focused rather than party-focused in governmental policy should be the focus. (8:30) Dr. Hampton describes his career focus on improving metabolic health, including how to incentivize doctors to help people discontinue medications and reduce the cost of care. (12:00) RFK Jr. may not always speak clearly to the mainstream public in a way that resonates. Dr. Hampton still faces challenges in the mainstream medical space, where other doctors struggle to embrace certain concepts; for example, many of his peers continue to have trouble accepting the idea that saturated fat is not harmful. (14:00) Despite the benefits of a low-carb or ketogenic diet and its positive effects on things like diabetes and other metabolic diseases, it is still not accepted by many doctors. Apparently, they didn't get the memo! (16:00) They discuss food deserts and their effects on the community. (21:00) Advocating and Taking Action Dr. Hampton describes a current concept in healthcare being initiated by Advocate Trinity. (22:00) Much of it is educating people about food and lifestyle, and helping them to change their habits for the better (28:00) Vinnie admits he is not a fan of GLP-1s, but he understands how they can be a valuable tool for teaching and helping people adopt new habits. (31:00) They discuss the negative aspects of GLP-1s. The muscle loss associated with GLP-1 is more pronounced than that observed with natural weight loss. Muscle is essential for so many reasons, including boosting insulin sensitivity. (38:00) It is the metabolic engine of the body! Increasing muscle mass prevents you from becoming fragile. (38:00) Dr. Hampton offers two programs: NEST, which stands for Nutrition, Exercise, Less Stress/More Sleep, and How You Think/Less Trauma. ROPE is for Relationships, Organism (avoiding bad/adding good), Pollutants, and Emotions. (46:00) @drtonyhampton is on Instagram, and his linktree is https://linktr.ee/drtonyhampton YouTube is the best place to find him: https://www.youtube.com/@DrTonyHampton If you are interested in the NSNG® VIP group, it will be reopening soon. But you can get on the wait list -https://vinnietortorich.com/vip/ More News If you are interested in the NSNG® VIP group, it will be reopening soon. But you can get on the wait list -https://vinnietortorich.com/vip/ Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! https://annavocino.substack.com/ Don't forget you can invest in Anna's Eat Happy Kitchen through StartEngine. Details are at Eat Happy Kitchen. https://eathappykitchen.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your review after watching my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries REVIEWS: Please submit your review after watching my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries

Support the show to get full episodes, full archive, and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists. Read more about our partnership. Sign up for Brain Inspired email alerts to be notified every time a new Brain Inspired episode is released. To explore more neuroscience news and perspectives, visit thetransmitter.org. My guest today is Dan Nicholson, Assistant Professor of Philosophy at George Mason University, here to talk about his little book, What Is Life? Revisited. Erwin Schrödinger's What Is Life is a famous book that people point to as having predicted DNA and influenced and inspired many well-known biologists ushering in the molecular biology revolution. But Schrödinger was a physicist, not a biologist, and he spent very little time and effort toward understanding biology. What was he up to, why did he write this "famous little book"? Schrödinger had an agenda, a physics agenda. He wanted to save the older deterministic version of quantum physics from the new indeterministic version. When Dan was on the podcast a few years ago, we talked about the machine view of biological systems, how everything has become a "mechanism", and how that view fails to capture what modern science is actually telling us, that organisms are unlike machines in important ways. That work of Dan's led him down this path to Schrödinger's What Is Life, which he argues was a major contributor to that machine metaphor so ubiquitous today in biology. One of the reasons I'm interested in this kind of work is because the cognitive sciences, including neuroscience and artificial intelligence, inherited this mechanistic perspective, and swallowed it so hard that if you don't include the word "mechanism" in your research paper, you're vastly decreasing your chances of getting your work published, when in fact the mechanistic perspective is one super useful perspective among many. Dan's website. Google Scholar. Social: @NicholsonHPBio; @djnicholson.bsky.social What Is Life? Revisited Previous episode: BI 150 Dan Nicholson: Machines, Organisms, Processes 0:00 - Intro 7:27 - Why Schrodinger wrote What is Life 15:13 - Aperiodic crystal and the meaning of code 21:39 - Order-from-order, order-from-disorder 28:32 - Appeal to authority 37:48 - Cell as machine 39:33 - Relation between DNA and organism (development) 44:44 - Negentropy 53:54 - Original contributions 58:54 - Mechanistic metaphor in neuroscience 1:16:05 - What's the lesson? 1:28:06 - Historical sleuthing 1:39:49 - Modern philosophy of biology

Includes a discussion on how our relationship with the franchise has changed as we’ve grown older. Presented by Corporal Hicks & RidgeTop, as well as community guest co-hosts from The Perfect Organism Podcast, JM Prater […] The post #229: Evolving Perspectives, How Our Relationship With The Franchise Has Changed fting. Perfect Organism Podcast appeared first on Alien vs. Predator Galaxy.

[Best of] Hologenomics - how organisms interact and evolve by Science Stories

Worshiping giant sturgeons at the Iron Gates in Barbara Kneževic's new film; keeping the Hot Club de Paris sound alive on the banks of the Tolka; and Navid Navab and Garnett Willis on their Organism platform, erected around a collection of organ pipes salvaged from a Montreal church.

One of the research edges of regenerative organization is empowering strong-willed geniuses to function brilliantly in teams and teams of teams.  Modern culture promotes developing strong egos which, when used unconsciously, fight against each other for control and domination. At the same time, you might be wishing for closeness, but too often being part of a community comes at the cost of your own individual expression.  A new possibility is emerging, one where your unique creation power and that of your teammates is the primary requirement for your team to thrive. We call this an organism.  And, it is probable that the hierarchical structures of authority-follower, boss-employee, teacher-student relationships are deeply embedded in you since childhood. The shift into evolving your team into a thriving organism is profound. It takes time, new energetic structures, emotional healing, thoughtware upgrades and a commitment to human potential beyond the reasonable.  The good news is that it is possible. The surprising fact is that the only way to be part of such team is to source it. If you are part of the organism you don't get to consume the organism. The gameworld builders of Possibility Management have been developing cutting-edge new thoughtwares, processes and skills needed for this shift, and we want to share them with you. This worktalk might be important for you if you are a spaceholder (manager, leader, director, etc…) of an already existing organization, if you are starting your own project or team, or if you are a consultant for businesses and gameworlds who have a true wish for greater flexibility and creative output.  See you there chic@s! Yours truly,  Anne-Chloé Destremau https://annechloedestremau.org 

Matters Microbial #112: Bacterial Size, Stress, and Antibiotic Resistance October 17, 2025 Today Dr. Petra Levin, the George and Irene Freiberg Professor of Biology at Washington University in St. Louis joins the #QualityQuorum to discuss her work with bacterial cell size, environmental stress on bacteria, and antibiotic resistance. Host: Mark O. Martin Guest: Petra Levin Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of the periplasm, found in Gram negative bacteria. An overview of beta-lactam antibiotics. The field of quantitative microbiology. An overview of B. subtilis.  An overview of E. coli.  An overview of Klebsiella.  The biography of Barbara McClintock, “A Feeling for the Organism.” A video explanation of the lac operon of E. coli. The LTEE program (Long Term Evolution Experiment) founded by Dr. Rich Lenski. The nomenclature of monoderm and diderm bacteria. A video explanation of peptidoglycan in bacteria. Penicillin binding proteins (PBP) and antibiotic resistance. A video about cell division in E. coli. A famous article coauthored by Dr. Elio Schaechter that describes cell growth and cell size in bacteria. A related article by Dr. Levin and colleagues. An overview of ESKAPE bacteria. An article from Dr. Levin's research group describing the relationship between pH and antibiotic resistance. An article about persister cells and their relevance to antibiotic resistance. Dr. Levin's faculty website. Dr. Levin's very interesting laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

A bubbly conversation with Nicole Ayres (LinkedIn) founder of Jumpsuit Agency. We spoke of her journey into Business 3.0. We spoke of storytelling, perspectives, creating portals, shifting world views and trust. We spoke of documentation instead of creation, death as a precondition for life, many reps of falling and what that does for a person. We also speak of magnetism and what becomes possible when you embody the change you wish to see. And finally we spoke of how getting to ease is not necessarily easy. Enjoy!

Send us a textThe biological roots of sleep are tied to mitochondrial metabolism.Episode Summary: Dr. Gero Miesenböck discusses the evolutionary and metabolic basis of sleep, exploring how mitochondrial energy production in neurons, particularly in fruit flies, drives the need for sleep to manage harmful byproducts like reactive oxygen species and lipid peroxides. They discuss how sleep-inducing neurons sense these byproducts, the role of mitochondrial dynamics, and the broader implications for why all animals, from jellyfish to humans, require sleep. The conversation also touches on how body size and metabolism influence sleep needs across species.About the guest: Gero Miesenböck, MD is a professor of physiology at the University of Oxford, renowned for his pioneering work in optogenetics and his research on the neurobiology of sleep using fruit flies and mice.Discussion Points:Sleep is universal across animals, even in jellyfish without centralized brains, suggesting a fundamental metabolic purpose tied to mitochondrial energy production.Mitochondria produce energy efficiently using oxygen but generate reactive oxygen species that can damage cells through lipid peroxidation, necessitating sleep to repair this damage.Sleep-inducing neurons in fruit flies contain sensors that track lipid peroxidation products, acting like a digital memory to signal when sleep is needed.Smaller animals with faster metabolisms, like mice, require more sleep and have shorter lifespans due to higher oxygen consumption and oxidative stress.Mitochondrial diseases in humans often cause intense tiredness, likely due to increased electron leaks in the mitochondrial energy production process.The evolutionary origin of sleep likely stems from the oxygen revolution 2.5 billion years ago, enabling complex life but requiring mechanisms like sleep to manage metabolic side effects.Caloric restriction reduces sleep need by lowering the production of harmful metabolic byproducts, supporting the link between metabolism and sleep.Reference paper:Study: Mitochondrial origins of the pressure to sleepRelated content:M&M 12: Organisms, Cities, Companies & the Science of Scale | Geoffrey West*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Hey Horror Fans!!!It's the second week of spooky season and we're joined by the one and only Henry Zebrowski, the podcasting legend, comedian, and actor you know from Last Podcast on the Left, Your Pretty Face Is Going to Hell, and The Wolf of Wall Street. Sean's been waiting years for this one, and it does not disappoint. We chat horror, aliens, and the blurry line between both, from Henry's years of UFO fascination to the psychic weirdness of the phenomenon itself. Plus, Henry tells us all about his upcoming film UFO: Unbelievably Friendly Organisms and how fans can help bring it to life through the ongoing Kickstarter campaign.It's a wonderful chat, perfect to absorb into your ear holes this spooky season, so if you're down to get abducted, put on your tin foil hats and COME HANG OUT!!!

HEADLINE: Pangea's Mega-Monsoons, Coal Formation, and the Unclassifiable Tully Monster BOOK TITLE: Other Lands, a journey through Earth's Extinct Worlds GUEST AUTHOR NAME: Thomas Halliday 200-WORD SUMMARY: This segment examines the Permian and Carboniferous eras. In the Permian (253 million years ago), the single supercontinent Pangea caused a mega-monsoon system involving extreme seasonal wetness and dryness. Sites like Moradi, Niger, show creatures adapted to this arid environment. Organisms included the bulk herbivore Umoist and the apex predator Gorgonops, a close relative of mammals with large canines. This period was immediately followed by the "Great Dying," the largest mass extinction event in Earth's history. The Carboniferous (390 million years ago) saw the first extensive forests. As trees fell into vast, tropical swamps, the water inhibited decay, leading to the preservation of organic material that eventually formed the world's coal deposits. This process sequestered carbon, contributing to lower atmospheric carbon dioxide concentrations later in history. The final topic is the Tully Monster(Tullimonstrum), a small, torpedo-shaped creature with eyes on stalks that remains a profound paleontological mystery. It is intensely debated whether this organism is a vertebrate, and because it has no known descendants, it is classified as an evolutionary experiment that did not pan out.

This is the first solo episode of Scaling Theory, where I take a deep dive into the literature. Building on a working paper titled “Adaptive Regulation,” I explore why “future-proof” laws so often fail in the face of rapid technological change, and how complexity science can guide us toward rules that adapt to the things they regulate. Drawing on recent EU digital acts and voices from law, economics, and complexity theory, I sketch the contours of a regulatory system that scales.You can follow me on X (@⁠⁠ProfSchrepel⁠⁠) and BlueSky (@⁠⁠ProfSchrepel⁠⁠).References:Schrepel, T., Adaptive Regulation (2025) https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5416454Ranchordás, S., & Van‘t Schip, M. (2020). Future-Proofing Legislation for the Digital Age. In Time, Law, and Change: An Interdisciplinary Study.Colomo, P. I. (2022). Future-Proof Regulation against the Test of Time: The Evolution of European Telecommunications Regulation. Oxford Journal of Legal Studies, 42(4).Chander, A. (2017). Future-proofing law. UC Davis Law Review.Powell, W. W., & Snellman, K. (2004). The Knowledge Economy. Annual Review of Sociology, 30.Perez, C. (2009). The Double Bubble at the Turn of the Century: Technological Roots and Structural Implications. Cambridge Journal of Economics, 33(4), 779–805.Allen, D. W., Berg, C., & Potts, J. (2025). Institutional Acceleration: The Consequences of Technological Change in a Digital Economy. Cambridge University Press.Colander, D., Holt, R. P. F., & Rosser, J. B. (2004). The Changing Face of Mainstream Economics. Review of Political Economy, 16(4).Arthur, W. B. (2009). The Nature of Technology: What It Is and How It Evolves. New York: Free Press.Buchanan, J. M., & Tullock, G. (1962). The Calculus of Consent: Logical Foundations of Constitutional Democracy. University of Michigan Press.Sowell, T. (2007). A Conflict of Visions: Ideological Origins of Political Struggles.West, G. (2017). Scale: The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies. Penguin Press.

Organisms are sensitive to temperature, but reproduction is likely to be affected at lower temperatures than survival. We're joined by Jessica McNeill & Caiti Smukowski Heil to talk about their work on meiosis in yeasts. Hosted on Acast. See acast.com/privacy for more information.

Cilvēka spējām nav robežu, tas ir iekarojis augstākās virsotnes pasaulē un pielāgojies dzīvei apstākļos, kādos nepieredzējis cilvēks nespētu izdzīvot. Kas notiek alpīnista ķermenī, kad viņš kāpj virsotnē, un kā augstkalnu iedzīvotāju organismi pielāgojušies dzīvei uz "pasaules jumta"? Raidījumā Zināmais nezināmajā analizē Līga Plakane, Latvijas Universitātes Medicīnas un dzīvības zinātņu fakultātes asociētā profesore, un alpīnists Jānis Busenbergs.

Attention///Attention///Attention///Henry Zebrowski's new film, "Unbelievably Friendly Organisms", has launched a Kickstarter! As part of the unveiling, we introduce this brand new interview with one of the future stars of "UFO" - Adult Film Legend and Psychotherapist Jenna Haze! Now's the time! Don't miss your chance to get in on the ground floor! WWW.UFO.MOVIE ///Discontinue///Discontinue For Live Shows, Merch, and More Visit: www.LastPodcastOnTheLeft.comKevin MacLeod (incompetech.com)Licensed under Creative Commons: By Attribution 4.0 Licensehttp://creativecommons.org/licenses/by/4.0/Subscribe to SiriusXM Podcasts+ to listen to new episodes of Last Podcast on the Left ad-free, plus get Friday episodes a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Ben has a new condition he needs new meds for, Brett's guys trip, plane diarrhea, and more.

Published September 11, 2025 In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, discuss troublesome organisms making headlines. Together, they explore:Vibrio vulnificus (01:09): How people get this “flesh-eating” bacteria, how it affects patients, and a recent case that brought it into the spotlight.Staying safe (03:44): Discover when to seek medical attention and how knowledge can protect you as Vibrio vulnificus bacterium becomes more prevalent. New World screwworm (06:50): How this parasitic infection damages human tissue, how it was previously eradicated, and why it's making the news again. ABCs of protection (12:16): A simple reminder to avoid exposure, use bug spray, and wear protective clothing to shield against hazardous organisms.Laboratory as first line of defense (13:34): Laboratorians have a critical role in identification and monitoring broader trends when these types of cases arise. ResourcesA-Zs for prevention and exposure risks

Episode 318 An ancient organism has been discovered that has been alive for at least 100,000 years. Found in the Siberian permafrost, this lifeform doesn't appear to have just remained dormant - but instead has actually been growing extremely slowly. Our understanding of life is already quite fuzzy, and this finding adds to the idea that life itself is a fuzzy state of being.  A breakthrough method of treating previously untreatable chronic pain is showing promise. An intuitive form of deep brain stimulation, guided by machine learning, has provided targeted relief to patients in a small trial. The method also improved various other conditions and may even help with weight loss. Find out how it works. Throughout history, dramatic changes in the climate often coincide with major revolutions and rebellions. Rapid warming or cooling often have a cascading effect on food production, leading to shortages and rising prices. As the effect of climate change increase today, will we see a repeat of history? Chapters: (00:00) Intro (00:22) 100,000-year-old organism (10:37) Brain implant treats chronic pain (18:02) How climate change leads to revolutions Hosted by Rowan Hooper and Penny Sarchet, with guests Alexandra Thompson, James Dinneen and Karen Lloyd. To read more about these stories, visit https://www.newscientist.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Asha Sharma leads AI product strategy at Microsoft, where she works with thousands of companies building AI products and has unique visibility into what's working (and what's not) across more than 15,000 startups and enterprises. Before Microsoft, Asha was COO at Instacart, and VP of Product & Engineering at Meta, notably leading product for Messenger.What you'll learn:1. Why we're moving from “product as artifact” to “product as organism” and what this means for builders2. Microsoft's “seasons” planning framework that allows them to adapt quickly in the AI era3. The death of the org chart: how agents are turning hierarchies into task networks and why “the loop, not the lane” is the new organizing principle4. Why post-training will soon see more investment than pre-training—and how to build your own AI moat with fine-tuning5. Her prediction for the “agentic society”—where org charts become work charts and agents outnumber humans in your company6. The three-phase pattern every successful AI company follows (and why most fail at phase one)7. The rise of code-native interfaces and why GUIs might be going the way of the desktop8. What Asha learned from Satya Nadella about optimism—Brought to you by:Enterpret—Transform customer feedback into product growth: https://enterpret.com/lennyDX—The developer intelligence platform designed by leading researchers: http://getdx.com/lennyFin—The #1 AI agent for customer service: https://fin.ai/lenny—Transcript: ⁠https://www.lennysnewsletter.com/p/how-80000-companies-build-with-ai-asha-sharma⁠—My biggest takeaways (for paid newsletter subscribers): ⁠https://www.lennysnewsletter.com/i/171413445/my-biggest-takeaways-from-this-conversation⁠—Where to find Asha Sharma:• LinkedIn: https://www.linkedin.com/in/aboutasha/• Blog: https://azure.microsoft.com/en-us/blog/author/asha-sharma/—Where to find Lenny:• Newsletter: https://www.lennysnewsletter.com• X: https://twitter.com/lennysan• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/—In this episode, we cover:(00:00) Introduction to Asha Sharma(04:18) From “product as artifact” to “product as organism”(06:20) The rise of post-training and the future of AI product development(09:10) Successful AI companies: patterns and pitfalls(12:01) The evolution of full-stack builders(14:15) “The loop, not the lane”—the new organizing principle(16:24) The future of user interfaces: from GUI to code-native(19:34) The rise of the agentic society(22:58) The “work chart” vs. the “org chart”(26:24) How Microsoft is using agents(28:23) Planning and strategy in the AI landscape(35:38) The importance of platform fundamentals(39:31) Lessons from industry giants(42:10) What's driving Asha(44:30) Reinforcement learning (RL) and optimization loops(49:19) Lightning round and final thoughts—Referenced:• Copilot: https://copilot.microsoft.com/• Cursor: https://cursor.com/• The rise of Cursor: The $300M ARR AI tool that engineers can't stop using | Michael Truell (co-founder and CEO): https://www.lennysnewsletter.com/p/the-rise-of-cursor-michael-truell• Inside ChatGPT: The fastest growing product in history | Nick Turley (Head of ChatGPT at OpenAI): https://www.lennysnewsletter.com/p/inside-chatgpt-nick-turley• GitHub: https://github.com• Dragon Medical One: https://www.microsoft.com/en-us/health-solutions/clinical-workflow/dragon-medical-one• Windsurf: https://windsurf.com/• Building a magical AI code editor used by over 1 million developers in four months: The untold story of Windsurf | Varun Mohan (co-founder and CEO): https://www.lennysnewsletter.com/p/the-untold-story-of-windsurf-varun-mohan• Lovable: https://lovable.dev/• Building Lovable: $10M ARR in 60 days with 15 people | Anton Osika (CEO and co-founder): https://www.lennysnewsletter.com/p/building-lovable-anton-osika• Bolt: http://bolt.com• Inside Bolt: From near-death to ~$40m ARR in 5 months—one of the fastest-growing products in history | Eric Simons (founder and CEO of StackBlitz): https://www.lennysnewsletter.com/p/inside-bolt-eric-simons• Replit: https://replit.com/•Behind the product: Replit | Amjad Masad (co-founder and CEO): https://www.lennysnewsletter.com/p/behind-the-product-replit-amjad-masad• He saved OpenAI, invented the “Like” button, and built Google Maps: Bret Taylor on the future of careers, coding, agents, and more: https://www.lennysnewsletter.com/p/he-saved-openai-bret-taylor• Sierra: https://sierra.ai/• Spark: https://github.com/features/spark• Peter Yang on X: https://x.com/petergyang• How AI will impact product management: https://www.lennysnewsletter.com/p/how-ai-will-impact-product-management• Instacart: http://instacart.com/• Terminator: https://en.wikipedia.org/wiki/Terminator_(franchise)• Porch Group: https://porchgroup.com/• WhatsApp: https://www.whatsapp.com/• Maslow's Hierarchy of Needs: https://www.simplypsychology.org/maslow.html• Satya Nadella on X: https://x.com/satyanadella• Perfect Match 360°: Artificial intelligence to find the perfect donor match: https://ivi-fertility.com/blog/perfect-match-360-artificial-intelligence-to-find-the-perfect-donor-match/• OpenAI's GPT-5 shows potential in healthcare with early cancer detection capabilities: https://economictimes.indiatimes.com/news/international/us/openais-gpt-5-shows-potential-in-healthcare-with-early-cancer-detection-capabilities/articleshow/123173952.cms• F1: The Movie: https://www.imdb.com/title/tt16311594/• For All Mankind on AppleTV+: https://tv.apple.com/us/show/for-all-mankind/umc.cmc.6wsi780sz5tdbqcf11k76mkp7• The Home Depot: https://www.homedepot.com/• Dewalt Powerstack: https://www.dewalt.com/powerstack• Regret Minimization Framework: https://s3.amazonaws.com/kajabi-storefronts-production/sites/2147500522/themes/2148012322/downloads/rLuObc2QuOwjLrinx5Yu_regret-minimization-framework.pdf—Recommended books:• The Thinking Machine: Jensen Huang, Nvidia, and the World's Most Coveted Microchip: https://www.amazon.com/Thinking-Machine-Jensen-Coveted-Microchip/dp/0593832698• Tomorrow, and Tomorrow, and Tomorrow: https://www.amazon.com/dp/0593466497Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.—Lenny may be an investor in the companies discussed.My biggest takeaways from this conversation: To hear more, visit www.lennysnewsletter.com

Never take a hammer to a spider and never underestimate a worm, even if it's smaller than a grain of rice. — Support and sponsor this show! Venmo Tip Jar: @wellthatsinteresting Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@wellthatsinterestingpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Bluesky: @wtipod Threads: @wellthatsinterestingpod Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@wti_pod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Listen on YouTube!! Oh, BTW. You're interesting. Email YOUR facts, stories, experiences... Nothing is too big or too small. I'll read it on the show: wellthatsinterestingpod@gmail.com WTI is a part of the Airwave Media podcast network! Visit AirwaveMedia.com to listen and subscribe to other incredible shows. Want to advertise your glorious product on WTI? Email me: wellthatsinterestingpod@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Energetic Health Institute Radio with Angela Bulaga CHN – Brain fog, fatigue, GI issues (gas, bloating, nausea, vomiting, constipation, diarrhea). Oral thrush (white patches in the mouth and throat, soreness, and in the corners of the mouth), vaginal yeast infections (itching, burning, and discharge), jock itch, and anal itching. Athletes' foot, skin rashes (Eczema; Red, moist, or scaly rash, sometimes in...

Energetic Health Institute Radio with Angela Bulaga CHN – Brain fog, fatigue, GI issues (gas, bloating, nausea, vomiting, constipation, diarrhea). Oral thrush (white patches in the mouth and throat, soreness, and in the corners of the mouth), vaginal yeast infections (itching, burning, and discharge), jock itch, and anal itching. Athletes' foot, skin rashes (Eczema; Red, moist, or scaly rash, sometimes in...

The desert ecosystem is often described as a fragile one – especially a thin layer found just under the soil's surface. We'll learn what biocrust can tell us about our environment. Plus, a summer camp for kids who are serious about clowning around.

Manu Prakash is many things—biologist, engineer, inventor, philosopher—but what he isn't is conventional. Following his instincts has led Manu to his most ambitious project yet: mapping the whole tree of life, with the help of everyone on this planet. Step one: make a cheap microscope anyone can use. Foldscope co-inventor Jim Cybulski describes their invention, and their dream to supply millions of microscopes to the masses. Manu has been recognized by the Hypothesis Fund as a Scout for his bold science and enabling others to pursue their big ideas. “The Leap” is a 10-episode audio series that profiles scientists willing to take big risks to push the boundaries of discovery. It premieres on Science Friday's podcast feed every Monday until July 21. “The Leap” is a production of the Hypothesis Fund, brought to you in partnership with Science Friday.Transcript is available on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

In this thrilling episode, we sit down with Eric Mintel, an acclaimed jazz musician, paranormal investigator, and experiencer from the mystique-laden region of Pennsylvania—a hotbed of high strangeness. Join us as we plunge into the heart of Eric's most chilling encounters, from unsettling spiritual attacks to jaw-dropping UFO sightings and elusive cryptids. Could some of the enigmatic objects lighting up our skies be living alien organisms? Eric and Tommy explore this provocative theory, sharing their own riveting UFO experiences that lend credence to this mind-bending possibility. Tune in for a captivating journey into the unknown, where the veil of reality thins, and the shadows whisper secrets that defy comprehension.https://youtube.com/@ericmintelinvestigates9241?si=DIyF6M_WQCtHjCqlWe are thrilled to announce the official launch of Let's Get Freaky merchandise! Our collection includes hoodies, t-shirts, mugs, stickers, and more. Explore the full range at http://tee.pub/lic/aQprv54kktw.Do you have a paranormal or extraordinary experience to share? We'd love to hear from you! Contact us to be a guest on the Let's Get Freaky podcast. Email us at letsgetfreakypodcast@mail.com or reach out via social media on Facebook, Instagram, X, TikTok, or YouTube at @tcletsgetfreakypodcast. Connect with us at https://linktr.ee/letsgetfreaky.

Artist Laurie Palmer believes they can. In her book, The Lichen Museum, Laurie explores what we can gain from learning to see life the way a lichen does.

Summary In this discussion, Andy welcomes back Kevin Eikenberry to talk about his new book Flexible Leadership: Navigate Uncertainty and Lead with Confidence. They discuss how leadership complexity increases with career progression and how Kevin's book offers practical guidance on managing ambiguity. The conversation delves into the concept of flexible leadership, the impact of uncertainty versus fear, the importance of context in decision-making, and why organizations should be seen as both machines and organisms. They also touch on the significance of rituals and handling paradoxes in leadership. If you're looking for insights on how to lead and deliver despite uncertainty and ambiguity, this episode is for you! Sound Bites “Leadership in many ways hasn't changed for centuries.” “Fear has an endpoint... Anxiety has no end. And that's such a bigger challenge for us.” “We should be thinking pilot, not policy.” “Are organizations more like machines or more like organisms? Well, both are true.” Chapters 00:00 Introduction 01:54 Start of Interview 00:24 What HASN'T Changed With Leadership 04:00 What Does Kevin NOT Mean by 'Flexible' Leadership? 06:19 Understanding Uncertainty and Fear 08:25 The Sense-Making Framework 12:58 Organizations: Machines or Organisms? 15:50 System One vs. System Two Thinking 18:29 Autopilot vs. Deliberate Decision Making 18:51 Understanding Flexors: Compliance vs. Commitment 19:11 The Flexor Concept in Leadership 22:53 Habits vs. Rituals: Navigating Uncertainty 25:49 Parenting and Leadership: Building Confidence 28:20 End of Interview 28:39 Andy's Comments After the Interview 33:13 Outtakes Learn More You can learn more about Kevin and his book at KevinEikenberry.com/Flexible-Leadership. For more learning on this topic, check out: Episode 54 with Roger L. Martin about his book The Opposable Mind Episode 47 with Henry Mintzberg about his book on why management is what we think it is. Episodes 360 and 455 with Janet Polach about her books to help us avoid mistakes as we grow as leaders. Thank you for joining me for this episode of The People and Projects Podcast! Talent Triangle: Power Skills Topics: Leadership, Project Management, Uncertainty, Fear, Organizational Behavior, Leadership Styles, Habits, Rituals, Ambiguity The following music was used for this episode: Music: Echo by Alexander Nakarada License (CC BY 4.0): https://filmmusic.io/standard-license Music: Tuesday by Sascha Ende License (CC BY 4.0): https://filmmusic.io/standard-license

Send us a textHappy Earth Day! There are two concepts that every person should understand to be a better Earthling: entropy and self-organization. It seems like a paradox, but systems on Earth are simultaneously breaking down into disorder and arranging themselves into complex superorganisms. Everything on Earth (well, really in the whole universe) is subject to the second law of thermodynamics, which means it all dies and decays. But with access to steady flows of energy, organisms, ecosystems, and human societies can hold back the death and decay for a spell. After dropping the kids off at the pool, Asher, Rob, and Jason cover the interplay of entropy and self-organization and contemplate how to manage the inevitability of entropy with elegance (beyond morphing into a lizard person).Originally recorded on 4/8/25.Warning: This podcast occasionally uses spicy language.Sources/Links/Notes:Geoffrey West, Scale: The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies, Penguin Books, 2018.Robin Wall Kimmerer, The Serviceberry: Abundance and Reciprocity in the Natural World, Scribner, 2024.William Rees, “End game: the economy as eco-catastrophe and what needs to change,” Real-World Economics Review, 2019.The laws of thermodynamics, as explained by the website “Physics for Idiots""Telegraph Road" - song by Dire StraitsDavid Owen, "Green Manhattan," The New Yorker, October 10, 2004.Other Crazy Town episodes you might like:Crazy Town 100 - A Temporary Techno Stunt: Tom Murphy on Falling out or Love with ModernityCrazy Town 35 - Self Domestication and Overshoot, or… the Story of Foxes and Russian MelodramaCrazy Town Bonus Riff - Vanilla Andreessen, Pygmy Marmosets, and Hi-Tech DelusionsSupport the show

Why are there so many Big Tech monopolies? And perhaps more importantly, should anything be done to stop them? In the final installment of this series, we talk to former Facebook insider Brian Amerige to learn about the inner workings of Silicon Valley's social media behemoth.Support the show: https://redpilledamerica.com/support/See omnystudio.com/listener for privacy information.

Why are there so many Big Tech monopolies? In Part Two, we continue our remarkable journey by talking to author and visionary Howard Bloom about a natural phenomenon almost completely ignored by the science community.Support the show: https://redpilledamerica.com/support/See omnystudio.com/listener for privacy information.