Podcasts about enable

FaZe ZooMaa, Octane, Attach, Enable, and Aches break down the Call of Duty League matches from 3/7/2026!

In this episode, let's talk about advanced Amazon seller strategies that are discussed only in private. We pull back the curtain on what elite sellers are quietly doing and what you should start testing next. Most sellers focus on the obvious levers, ads, keywords, and pricing, while the real winners quietly play a different game. In this AM/PM episode, Bradley Sutton and 8-figure seller Leo Sgovio unpack the strategies top Amazon sellers rarely say out loud, from backend ranking fixes to AI-driven creative and off-Amazon intel.   Leo breaks down how Amazon browse tree changes can silently wreck rankings, and how to repair it using Category Listing Reports plus the BrowseTree Guide so your attributes match what Amazon actually accepts. Then he shows how some sellers “launch” with huge review counts by consolidating variations and even leveraging international review history. From there, the episode shifts into speed: AI tools to generate better hero images, systems to make your site crawlable for LLMs, and how press releases can help you appear in Google AI Overviews faster than traditional SEO.   Finally, Leo goes outside Amazon: using Reddit for GEO, finding Shopify winners by tracking checkout traffic, and reverse-engineering competitor funnels through the Meta Ad Library and presell pages. He closes with a warning every brand should hear: a black-hat cloaking attack that can suppress your Buy Box. If you want tactics you can apply today and threats you need to defend against tomorrow, this one is a must-listen. In episode 502 of the AM/PM Podcast, Bradley and Leo discuss: 00:00 - Introduction 02:34 - Strategy 1: How To Fix Your Tanked Rankings Due To A Wrong Product Categorization 12:11 - Strategy 2: How To Uncover Your Competitor Just Launched a Product with 100+ Reviews 17:02 - Strategy 3: Quickly Brainstorm New Hero Image with this Gemini Gem 19:35 - Strategy 4: Enable your Website to be Indexed by LLMs with this Automated GPT 24:09 - Strategy 5: Show Up in Google AI Overview in 7 Days 27:18 - Strategy 6: Where to Find Inspiration for your Product Creatives and Listing Images 31:38 - Strategy 7: Dominate Reddit for AEO/GEO 36:56 - Strategy 8: Discover Shopify's Top Selling Stores 40:24 - Strategy 9: Exploiting Competitors Outside Traffic Funnels 45:48 - How to get more Advanced Strategies Monthly 53:56 - Strategy 10: How to Control the Order of the Variations on your Listing 54:47 - Legal and Ethical Disclosure 54:57 - Threat Alert: Cloaking attack with fake retail pages can suppress your Buy Box, how it works, and what to watch for

What does it take to scale disability inclusion across an entire workforce? In this episode, National Organization on Disability leaders Beth Sirull and Sara Walsh explain how the EnAble Learning digital training system helps organizations embed inclusion, adaptability, and workforce readiness into their everyday operations.Show Notes:Beth Sirull and Sara Walsh of the National Organization on Disability share how their new EnAble Learning courses are helping organizations of all sizes create welcoming, productive workplaces through engaging, accessible online training. Here are some of their key points:Disability inclusion is a business imperative, not philanthropy. Beth Sirull shared that companies fully integrating disability inclusion hire twice as many people with disabilities—and promote five times as many—demonstrating measurable business impact.Most disabilities are invisible—and often undisclosed. Beth emphasized that the majority of disabilities are not visible, and disclosure rates are low due to stigma, making proactive inclusion essential.Scalable, on-demand training increases access and impact. Sara Walsh explained that EnAble Learning was created to make high-quality disability inclusion training accessible to organizations of all sizes, especially those unable to support in-person sessions.Engagement and relevance were non-negotiable in the digital experience. Sara noted that the courses were intentionally designed to be interactive, practical, and manager-focused—avoiding “click-through” compliance training in favor of meaningful learning.Inclusion benefits everyone—and anyone can join the disability community at any time. Sara pointed out that disability is a community anyone may become part of at any stage of life, reinforcing why inclusive practices matter across the entire workforce.Learn more about National Organization on Disability's enAble LearningPowered by Learning earned Awards of Distinction in the Podcast/Audio and Business Podcast categories from The Communicator Awards and a Gold and Silver Davey Award. The podcast is also named to Feedspot's Top 40 L&D podcasts and Training Industry's Ultimate L&D Podcast Guide. Learn more about d'Vinci at www.dvinci.com. Follow us on LinkedInLike us on Facebook

Plus: South Korean stocks see a record drop as fighting in the Mideast ripples across Asian economies. And James Talarico wins Texas's Senate Democratic primary. Daniel Bach hosts. Sign up for WSJ's free What's News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices

FaZe ZooMaa, Octane, Temp, Aches, and Enable break down the Call of Duty league matches from 2/28/2026

In this episode, Pål and Ville sit down with Joonas Tomperi, CEO and co-founder of Enable Banking — and quickly realise this is less about APIs and more about mindset.Yes, we talk open banking. Yes, PSD2 makes an appearance. But the real story is what it takes to build a fintech in a heavily regulated industry when half the market says “you're too late” and the other half says “nothing works yet.”Joonas shares:.- Why starting a fintech at 35 (not 22) was a strength, not a weakness.- What it's like launching into PSD2 when the APIs technically exist… but not really.- How to turn regulatory slowness and pandemic chaos into competitive advantage.- Why Enable Banking chose product over consulting — even when cash flow would have been easier the other way.- The uncomfortable truth about fundraising: it's basically advanced dating, but with more spreadsheetsWe also get into founder psychology — risk vs opportunity, when to bring in stronger operators, and why the best CEOs are willing to replace themselves if it's right for the company.And in true Nordic fashion, we ask the big question:Why doesn't Finland have five fintech Nokias yet?Along the way, there's flu, pirate eye patches, 90s bank servers covered in dust, and a gentle reminder that connecting to “thousands of APIs” is slightly harder than plugging in a phone charger abroad.If you care about open banking, founder grit, or building something meaningful in a market that moves slower than your pitch deck suggests — this one's for you.Episode hosted by Pål Krogdahl & Ville SointuEpisode produced and edited by Fintech Daydreaming- Email us on Hello@FintechDaydreaming.com- Fintech Daydreaming home page - https://www.FintechDaydreaming.com- Fintech Daydreaming on Twitter - https://twitter.com/FintechDaydream- Fintech Daydreaming on LinkedIn - https://www.linkedin.com/company/fintech-daydreaming- Pål Krogdahl - https://www.linkedin.com/in/krogdahl/- Ville Sointu - https://www.linkedin.com/in/ville-sointu-54682b/

26 Feb 2026. Etihad Airways has posted its best-ever financial results, with 2025 net profit up 47% as passenger numbers climbed 21% and the fleet expanded by 30%. We speak to the CFO about the numbers behind the growth. Plus, Uber will soon let users in Dubai book a Joby Aviation air taxi through its app, our Executive Reporter Georgia Tolley speaks to Uber’s President of Autonomous Mobility & Delivery, Sarfraz Maredia. And we talk “Ramadanomics” and retail expansion with Marks & Spencer. See omnystudio.com/listener for privacy information.

Sean Pontin is the CEO of Enable Jersey, the leading disability organisation on the Island of Jersey in the Channel Islands and today he'll tell us about the initiatives the organisation has undertaken to make island more inclusive and accessible for people with disabilities.Learn more about Enable Jersey via the link to their website below:https://www.enablejersey.org/If you would like to reach out feel free to send an email to: atelierfuralle@gmail.com. You can also leave a review of the podcast and follow this show on:Instagram:https://instagram.com/atelierfuralle?igshid=OGQ5ZDc2ODk2ZA%3D%3D&utm_source=qr⁠⁠Facebook:⁠⁠https://www.facebook.com/profile.php?id=61551850785306⁠⁠Feel free to join the "JD Dragon Disability Rights Podcast" Facebook Group:https://www.facebook.com/share/g/12Eit9sBPuR/?mibextid=wwXIfrSnapchat:https://t.snapchat.com/FVWn1jmTDiscord ServerJD DragonX (formerly known as Twitter):@JDDragonPodcast

God Will Enable You John 14:18, 16:7

Ethereum's next big leap might not look like a single “flip the switch” moment—but it could change how the chain verifies everything. In this episode, Ansgar Dietrichs comes back to unpack the ZK EVM: why “re-executing every block” has been Ethereum's hidden scaling tax, how real-time proofs finally make a different verification model viable, and what it would take to transition safely without sacrificing the verifiability that keeps Ethereum credibly neutral. They explore the three true bottlenecks of blockchain scaling (compute, IO, bandwidth), the roadmap from optional proofs to mandatory proofs, and why client diversity could look radically different in a ZK-native future. ---

Recent data highlights a growing disconnect between technology spending and measurable business outcomes, with small business optimism softening and widespread skepticism about the benefits of artificial intelligence. The transcript cites an 80% rate of firms seeing no noticeable AI-driven productivity improvements, while trust in technology companies, particularly AI vendors, has declined globally according to the Edelman report. For MSPs, this presents a risk of credibility gaps, especially for those selling AI solutions without corresponding outcome data, as client trust and spending habits grow more discerning in the face of unfulfilled promises. Further context is provided by economic indicators showing a resilient U.S. economy, yet persistent challenges for small businesses. The NFIB Small Business Optimism Index has dropped slightly to 99.3, with insurance costs and labor quality as major pain points; only 16% of business owners expect higher sales. At the same time, IT professionals face salary compression—median IT salaries fell from $145,000 in 2023 to $115,000 in 2024—despite a severe shortage of skilled cloud, AI, and infrastructure talent, as less than 10% of hiring managers are confident in filling in-demand roles. Additional market pressures include rising technology budgets—three-quarters of CFOs anticipate larger tech allocations, but headcount increases are slowing and tech spending faces a widening affordability gap due to sector-specific inflation outpacing budget growth. Vendor-specific developments, such as Western Digital exhausting hard drive capacity for 2026 and Enable reporting 12.8% revenue growth alongside ongoing losses and a 65% stock decline since 2021, illustrate structural risks. Vendor rationalization and strategic uncertainty are likely outcomes for MSPs relying heavily on underperforming partners. Key takeaways for service providers and IT leaders include the need for caution in messaging and solution positioning: outcome data and defensible value propositions are essential when advocating AI or cloud services. Salary data should be weighed against demand-side evidence to avoid retention failures. Finally, dependency on vendors with deteriorating financial outlooks heightens operational risk; providers should proactively assess alternatives and align with financially sustainable partners to reduce exposure during vendor consolidation cycles or market restructures. Four things to know today 00:00 AI Productivity Gap Widens as Trust Drops — MSPs Selling Outcomes They Can't Measure Face CFO Audits  04:51 IT Median Salary Dropped 20% in 2024, But Only 7% of Hiring Managers Can Fill AI and Cloud Roles 07:26 IT Inflation Hits 6.9% as CFOs Concentrate Spend; Western Digital Fully Booked Through 2026 10:28 N-Able Beats Revenue, Misses Earnings as 2026 Growth Guidance Drops to 8–9%   Sponsored by: CometBackup Small Biz Thoughts Community

FaZe ZooMaa, Parasite, Aches, Temp, and Enable break down the call of duty league matches from 2/23/2026!

FaZe ZooMaa, Ben J, Attach, Temp, Octane, and Enable break down the Call of Duty League matches from 2/20/2026!Like, comment, subscribe!

Each of your employees is a potential content marketing, brand-building, lead-generating goldmine.But to tap into this opportunity, you need to move away from using a one-size-fits-all strategy.In this episode of The Content 10x Podcast, host Amy Woods talks about why it's important to give up some control, avoid using the same approach for everyone, and help employees show up online in a genuine way.Amy shares why it's better to ditch forced formats and scripts, discusses ways to build trust with different messages, and explains how to set up systems that empower unique voices to show up in multiple ways.If you want to add employee-led content to your brand strategy, this episode is for you! But before you jump in, check out episodes 348 and 349 for part one and part two of our content deep dive.Find out:What types of content and messaging work best on LinkedInHow to help employees feel confident posting onlineHow to create systems that support employee content at scaleWhere to find inspiration for LinkedIn postsWhy it's important to analyze what is getting attention onlineImportant links & mentions:Episode 347: Why Not All Content Works Everywhere (And Why That's a Good Thing) https://www.content 10x.com/347Episode 348 (Part 1): Why Employee-Led Content is the Biggest B2B Advantage https://www.content 10x.com/348Episode 349 (Part 2): How to Build an Employee-Led Content System That Actually Works https://www.content 10x.com/349Amy on LinkedIn https://www.linkedin.com/in/amywoods2/Content 10x: https://www.content10x.com/Amy's book: www.content10x.com/book (Content 10x: More Content, Less Time, Maximum Results)Amy Woods is the CEO and founder of Content 10x, a creative agency that provides specialist content strategy, creation and repurposing support to B2B organizations.She's also a best-selling author, hosts two content marketing podcasts (The Content 10x Podcast and B2B Content Strategist), and speaks on stages all over the world about the power of content marketing.Join thousands of business owners, content creators and marketers and get the latest content marketing tips and advice delivered straight to your inbox every week https://www.content10x.com/newsletter

Join hosts Tor and Romain as they sit down with Søren Gjesse, Chris Craik, and Shai Barack. This week, the team dives into R8, the whole-program optimizer that handles the "last mile" of your code before it runs on a device. Learn why implementing R8 is effectively like giving your users a "free hardware upgrade" by making their current devices perform like models that are years newer. Enable app optimization → https://goo.gle/R8-Optimizer Chapters: 0:00 - Intro 0:23 - What is R8? 1:16 - R8 vs D8 1:40 - Tree Shaking & Dead Code 4:14 - Handling Reflection 10:10 - Performance Co-Optimization 13:03 - Kotlin-Specific Gains 16:22 - Real-World Impact 41:50 - Jetpack Compose & R8 50:51 - Keep annotations 1:03:49 - The "Free Hardware Upgrade"

FaZe ZooMaa, Ben J, Attach, Temp, Octane, Aches, Parasite, and Enable break down the call of duty league matches from 2/14 - 2/15

What happens when people “fear the Lord” in a healthy way? Explore how this can lead to wisdom and relationship with God!Receive The Bible's wisdom books remind us again and again that the fear of the Lord is where real wisdom begins—and that's the kind of wisdom we need for everyday life. From big decisions to ordinary moments, we all need God's perspective to help us navigate what's in front of us. Proverbs offers that wisdom with a hopeful, “glass half-full” lens, giving practical guidance for daily choices. Ecclesiastes meets us in the tension, naming life's frustrations and uncertainties with a more “glass half-empty” honesty. And Job takes us deeper, showing that a healthy fear of the Lord isn't about being afraid—it's about being drawn into a real, trusting relationship with God as we learn to revere all of who He is, even when life doesn't make sense.  Reflect Read the verses connected with this episode below. As you reflect on the Scripture, what stands out to you? Proverbs 1:5 Proverbs 24:5 Ecclesiastes 1:18 Proverbs 24:3-4 Ecclesiastes 2:20-21 Ecclesiastes 9:11 Ecclesiastes 12:13-14 Job Psalm 22:22-24 Psalm 19:7-10 Psalm 25:8-14 Would you say you identify more with the “glass half-full" approach to wisdom in Proverbs, or the “glass half-empty" approach of Ecclesiastes? Job's story demonstrates that fearing God is relational and not transactional (see Job 1:9). Why is it important to fear God for who He is and not for what He does? How does this type of reverent fear strengthen your relationship with God? God assured Job of His power and presence and unlimited perspective. How did this help Job have a healthy fear of God (see Job 42:1-6)? How can this help you have a healthy fear of God? Fear of the Lord invites you into a deeper relationship with Him (see Psalm 25:14). How can that help you live wisely today?  Respond (Use this prayer to start a conversation with God) “Jesus, help me have a healthy fear of God that allows me to live with wisdom throughout my life. Enable me to revere God for who He is and not for what He does so that I may deepen my relationship with You. Open my eyes to see more clearly the wonder and awe of who You are.”   Discover more about the topics in this episode with these recommended resources Mentioned in this episode: Ecclesiastes | Week 1  Ecclesiastes | Week 2  Our Daily Bread Mobile App  Listen: Proverbial Wisdom  A Life of Wisdom and the Proverbs 31 Woman  Read: Reverent Fear  Understanding the Bible: The Wisdom Books  Watch: Mount Arbel - Sermon on the Mount and the Great Commission 

We Don't Need No Education. In this episode, we read The End of Education by Neal Postman, discussing the mechanisms of public education, religious catechesis, the influence of the Enlightenment and psychoanalysis on contemporary learning, and what happens when fiction replaces truth as the basis of meaning. This and much, much more on today's show! SHOW NOTES:  The End of Education https://amzn.to/4qGylnd   More from 1517: Support 1517 Podcast Network: https://www.1517.org/donate-podcasts 1517 Podcasts: http://www.1517.org/podcasts 1517 on YouTube: https://www.youtube.com/@1517org 1517 Podcast Network on Apple Podcasts: https://podcasts.apple.com/us/channel/1517-podcast-network/id6442751370 1517 Events Schedule: https://www.1517.org/events 1517 Academy - Free Theological Education: https://academy.1517.org/   What's New from 1517: Being Family by Dr. Scott Keith https://shop.1517.org/products/9781964419961-being-family The Essential Nestingen: Essays on Preaching, Catechism, and the Reformation https://shop.1517.org/products/9781964419121-the-essential-nestingen  Philip Melanchthon's Commentary on Ecclesiastes https://shop.1517.org/products/9781964419299-philip-melanchthons-commentary-on-ecclesiastes  Face to Face: A Novel of the Reformation by Amy Mantravadi https://shop.1517.org/products/9781964419312-face-to-face  Untamed Prayers: 365 Daily Devotions on Christ in the Book of Psalms by Chad Bird https://www.amazon.com/Untamed-Prayers-Devotions-Christ-Psalms/dp/1964419263    More from the hosts: Donovan Riley https://www.1517.org/contributors/donavon-riley  Christopher Gillespie https://www.1517.org/contributors/christopher-gillespie   CONTACT and FOLLOW: Email mailto:BannedBooks@1517.org  Facebook https://www.facebook.com/BannedBooksPod/  Twitter https://twitter.com/bannedbooks1517   SUBSCRIBE: YouTube https://www.youtube.com/@BannedBooks Rumble https://rumble.com/c/c-1223313  Odysee https://odysee.com/@bannedbooks:5 Apple Podcasts https://podcasts.apple.com/us/podcast/banned-books/id1370993639  Spotify https://open.spotify.com/show/2ahA20sZMpBxg9vgiRVQba  Overcast https://overcast.fm/itunes1370993639/banned-books    MORE LINKS: Tin Foil Haloes https://t.me/bannedpastors Warrior Priest Gym & Podcast https://thewarriorpriestpodcast.wordpress.com   St John's Lutheran Church (Webster, MN) - FB Live Bible Study Group https://www.facebook.com/groups/356667039608511  Gillespie's Sermons and Catechesis http://youtube.com/stjohnrandomlake  Donavon's Substack https://donavonlriley.substack.com Gillespie's Nostr https://primal.net/p/nprofile1qqszfrg80ctjdr0wy5arrseu6h9g36kqx8fanr6a6zee0n8txa7xytc627hlq   Gillespie Coffee https://gillespie.coffee   Gillespie Media https://gillespie.media  

FaZe ZooMaa, Attach, BenJ, Octane and Enable break down The Call of Duty league matches from 2/13/2026!

FaZe ZooMaa, Aches, Ben, Temp, Octane, Parasite, and Enable break down the recent CDL Drama!Like, comment, subscribe!

On the show floor at CES in Las Vegas, Ohsnap Industrial Design Engineer James Stone demos MCON, their  slide-out, pocketable mobile gaming controller that automatically connects to your iPhone for instant play. It supports low-latency casting to a big screen via dock or portable HDMI adapter, delivering console-style gaming anywhere.  Show Notes: Support:      Become a MacVoices Patron on Patreon     http://patreon.com/macvoices      Enjoy this episode? Make a one-time donation with PayPal Connect:      Web:     http://macvoices.com      Twitter:     http://www.twitter.com/chuckjoiner     http://www.twitter.com/macvoices      Mastodon:     https://mastodon.cloud/@chuckjoiner      Facebook:     http://www.facebook.com/chuck.joiner      MacVoices Page on Facebook:     http://www.facebook.com/macvoices/      MacVoices Group on Facebook:     http://www.facebook.com/groups/macvoice      LinkedIn:     https://www.linkedin.com/in/chuckjoiner/      Instagram:     https://www.instagram.com/chuckjoiner/ Subscribe:      Audio in iTunes     Video in iTunes      Subscribe manually via iTunes or any podcatcher:      Audio: http://www.macvoices.com/rss/macvoicesrss      Video: http://www.macvoices.com/rss/macvoicesvideorss

On the show floor at CES in Las Vegas, Ohsnap Industrial Design Engineer James Stone demos MCON, their  slide-out, pocketable mobile gaming controller that automatically connects to your iPhone for instant play. It supports low-latency casting to a big screen via dock or portable HDMI adapter, delivering console-style gaming anywhere.  http://traffic.libsyn.com/maclevelten/MV26067.mp3 Show Notes: Support:      Become a MacVoices Patron on Patreon      http://patreon.com/macvoices      Enjoy this episode? Make a one-time donation with PayPal Connect:      Web:      http://macvoices.com      Twitter:      http://www.twitter.com/chuckjoiner      http://www.twitter.com/macvoices      Mastodon:      https://mastodon.cloud/@chuckjoiner      Facebook:      http://www.facebook.com/chuck.joiner      MacVoices Page on Facebook:      http://www.facebook.com/macvoices/      MacVoices Group on Facebook:      http://www.facebook.com/groups/macvoice      LinkedIn:      https://www.linkedin.com/in/chuckjoiner/      Instagram:      https://www.instagram.com/chuckjoiner/ Subscribe:      Audio in iTunes      Video in iTunes      Subscribe manually via iTunes or any podcatcher:      Audio: http://www.macvoices.com/rss/macvoicesrss      Video: http://www.macvoices.com/rss/macvoicesvideorss

Discover how AI-powered ad scrapers are transforming ecommerce competitor research. From understanding what an ad scraper does to examining leading platforms, we unpack the tools and ethics every marketer should know. Find out more at https://www.gethookd.ai/blog/best-meta-ad-library-scraper-tools GETHOOKD LLC City: Miami Address: 40 SW 13th street Website: https://www.gethookd.ai/

With Valentine's season in full swing, Enable Ireland is putting a fun twist on romance, encouraging people to break up with their stuff for a great cause. On Tuesday's Morning Focus, Alan Morrissey was joined by Regional Area Manager with Enable Ireland, Mary Hynes to tell us about their biggest-ever ‘Break Up' campaign and how locals in Ennis can get involved. Image (c) Enable Ireland

Subscribe to our Newsletter: https://theultimatepartner.com/ebook-subscribe/ Check Out UPX: https://theultimatepartner.com/experience/ https://youtu.be/-flNeKF6CxQ?si=xIIQ4LUl7oraQjkg Microsoft’s Cyril Belikoff joins Vince Menzione to reveal the seismic shift occurring within the newly reimagined Microsoft Marketplace. As the industry moves toward a predicted $300 billion partner opportunity by 2030, this discussion deconstructs the evolution of the “Frontier” vision, the launch of the AI apps and agents category, and the critical “Resale Enabled Offer” (REO) that is currently doubling deal sizes for early adopters. Whether you are a software company looking to scale globally or a reseller aiming to stitch together complex AI solutions, the message is clear: the flywheel is already spinning, and those who wait for a “perfect strategy” risk being permanently displaced by more agile competitors who are getting their feet wet today. Key Takeaways The Microsoft Marketplace has been reimagined into a single destination for discovering, buying, and deploying AI apps and agents. Analysts predict a staggering $300 billion opportunity for partners within the Microsoft Marketplace by 2030. The new Resale Enabled Offer (REO) allows software companies to authorize channel partners to resell on their behalf across specific geographies with minimal overhead. Cloud migration is far from over, as massive amounts of on-premise data and ISV apps still need to be modernized for the AI era. Marketplace deal sizes are doubling as customers use Azure commitments to retire their marketplace acquisition costs. Successful partners are moving away from “boiling the ocean” strategies and instead focusing on transacting one or two deals to learn the ecosystem’s mechanics. If you're ready to lead through change, elevate your business, and achieve extraordinary outcomes through the power of partnership—this is your community. At Ultimate Partner® we want leaders like you to join us in the Ultimate Partner Experience – where transformation begins. Key Tags: Microsoft Marketplace, AI apps and agents, Resale Enabled Offer, REO, Cyril Belikoff, Azure Marketplace, AppSource, cloud solutions, software companies, digital transformation, AI strategy, channel led sales, ISV solutions, cloud migration, Azure commitments, Microsoft Cloud, Frontier vision, MSP opportunity, marketplace transacting, AI monetization, global scale, procurement, IT deployment, technical modernization, partner ecosystem, business applications. Opening Lines: [00:00:00] Cyril Belikoff: Marketplace is really the extension of our vision for Frontier, uh, and the Microsoft Cloud. You know, the, the Microsoft technology takes a customer a long way, but in many ways to complete the thought. If you’re in football terms, you want to cross over the line and score touchdown. You can’t just get, uh, to the red zone. [00:00:20] Cyril Belikoff: You actually need partner solutions. [00:00:26] Vince Menzione: So let’s, let’s kick off to Marketplace a little bit right, too, because, uh, it’s been a big year for Marketplace, or 20, the first half of 2026 fiscal year 2026 has been a big year. A lot of announcements, a lot of things going on in the world, in marketplace. Where do we wanna start there? Let’s recap some of it. [00:00:44] Cyril Belikoff: Yeah. Um, so, um. It feels like a long time ago, but in, at the end of September, [00:00:51] Vince Menzione: yeah. [00:00:52] Cyril Belikoff: Um, at the AR tour, uh, in Chicago, we announced a new Microsoft marketplace. We reimagined that experience. It’s a new customer experience, single destination for customers to. You know, discover, find, try, buy, and deploy cloud solutions, AI apps and agents all in one place. [00:01:11] Cyril Belikoff: And so historically, we’ve had a little bit, uh, of decentralization. We had this thing called the Azure Marketplace and AppSource for different experiences. AppSource was more for teams and, and copilot. Um, and, and office, Azure Marketplace. Of course, that was for Azure. We brought all of that into one place. [00:01:30] Cyril Belikoff: So customers, whether they are looking for a SaaS solution running on Azure, an agent that snaps into copilot, an experience that runs in our security store, now they can go to one place. Um. marketplace.microsoft.com. It’s one, it’s the new Microsoft marketplace. And we have an, of course, we have a, we had, we launched a brand new category, AI apps and agents, and we launched that category in September. [00:01:54] Cyril Belikoff: Uh, bringing together numerous, uh, uh, partner offerings. Yeah. And today we have the largest catalog, um, probably in the mid four thousands of AI and agents. Wow. Available to customer. So fantastic. There was, there was quite a big moment in September. Um, and then fast forward a little bit to November, we announced a resale enabled offer, um, at Ignite [00:02:15] Vince Menzione: eo. [00:02:16] Vince Menzione: Eo [00:02:16] Cyril Belikoff: eo. I, [00:02:17] Vince Menzione: I like EO reminds me of the band back in the day. [00:02:19] Cyril Belikoff: Yeah. R Speedwagon. There you go. Uh, well, and it’s, it’s not that far from it because Oreo accelerates. Yeah. Um, what partners can do, uh, with the marketplace and really connects. Software companies and resellers, which I’m sure we’ll talk about in a second. [00:02:34] Cyril Belikoff: But that’s really the recap, um, of, uh, you know, the new Microsoft marketplace, how we enabling it for, uh, for partners through the the resell enable offer. [00:02:45] Vince Menzione: So, I know we talked on this a little bit, but I wanna maybe just expand on it. What does the frontier push and the marketplace evolution mean for partners? [00:02:53] Vince Menzione: Because I, I think it’s huge for both, for these partners to really monetize and accelerate their success working with you. [00:03:00] Cyril Belikoff: Yeah. So, um. Marketplace is really the extension of our vision for Frontier, uh, and the Microsoft Cloud. You know, the, the Microsoft technology takes a customer a long way, but in many ways to complete the thought and to, you know, uh, uh. [00:03:20] Cyril Belikoff: If you’re in football terms, you wanna cross over the line and score a touchdown, you can’t just get, uh, to the red zone. You actually need partner solutions. [00:03:28] Vince Menzione: Yeah. [00:03:29] Cyril Belikoff: Uh, and so that’s where the partner solutions, combined with Microsoft’s first party offerings become a really, really. Great offering and powerful offering for our customers to, to become Frontier. [00:03:40] Cyril Belikoff: So we have obviously a ton of AI experiences, our own co-pilot experiences, uh, Microsoft Foundry, which is a platform for ai, but in, in many ways, we need those industry solutions. We need those AI apps and agents from partners to complete that offering. And that’s really. How it comes together and, uh, you know, uh, I heard you from o was just on before me. [00:04:01] Cyril Belikoff: They actually predict that the Microsoft marketplace, uh, is a 300 billion partner opportunity by 2030. Yeah, they’re talking about, I think, mid eighties growth. We have literally seen our business for the last three years, and we are in the middle of our, uh, you know, third year doubling. And so when you get three or four years of doubling every year, that’s compounded doubling. [00:04:24] Cyril Belikoff: Um, so, uh, we have seen lots of momentum from customers, lots of interest. We’ve made it, you know. Interesting for customers. Um, and incentivize our customers with their Azure commitments that can retire their marketplace, uh, acquisitions that way. We’ve made it, we’ve put incentives for partners and for our own sellers. [00:04:44] Cyril Belikoff: So we really creating the flywheel for everybody in the market to see value from, uh, the marketplace. So. Like, like, like you mentioned, like m the, uh, you know, suggested [00:04:55] Vince Menzione: Yeah. [00:04:55] Cyril Belikoff: It’s only exploding the opportunity on marketplace. [00:04:58] Vince Menzione: Well, and you both touched on the fact that the data is not in the cloud yet. [00:05:02] Vince Menzione: Not all the data that needs to be in the cloud in order to drive the future of where we wanna go from a society. Mm-hmm. And from a business application perspective needs to be in the cloud. So huge opportunities for partners around data states, around securing that data, governing that data, and so on, on top of all the business applications, [00:05:19] Cyril Belikoff: right? [00:05:19] Vince Menzione: As promise. So incredible. Yep. So let’s [00:05:22] Cyril Belikoff: talk about, yeah. The call migration. The call migration, people think that is over and it’s long from over because customers have plenty, uh, on premise, uh, not only Microsoft technology, but the, the, the, the software company or the ISV app that sits on top of it. Yeah. [00:05:36] Cyril Belikoff: And that needs to be migrated, managed, modernized, um, and marketplace is a big part of that too. Um, but there’s so many services and, um, opportunities around it. [00:05:45] Vince Menzione: Incredible opportunity. Let’s talk about the channel and the channel opportunity. You, you touched on this earlier, right? So this really lighting up the channel. [00:05:53] Vince Menzione: I saw this loud and clear when we were at Ignite. Like this is a huge opportunity for the Es, for the resellers, for all the partners. And as part of REO, you’ve got huge opportunities you’re laying out for them for the 500,000 part partners. You know, we talk about the Bill Gates moment down here in Boca. [00:06:09] Vince Menzione: This is where it all started. Uh, yep. How, how do you think about marketplace in the channel today? [00:06:16] Cyril Belikoff: Yeah. You know, it’s, um, it’s vital. You know, we have a customer need, um, from. The smallest is small business all the way to enterprise. And the really, the only way we serve that, the only way we know how to serve that is with our partners from the largest of partners that serve our top enterprises down through, um, what we call small and medium and then down to our small business. [00:06:41] Vince Menzione: Yeah. [00:06:41] Cyril Belikoff: Um, and so, you know, we have seen our. You know, while our, we’ve seen a doubling of our business, we’ve seen three, three and a half to four x doubling of our channel led sales. [00:06:53] Vince Menzione: Yeah. [00:06:54] Cyril Belikoff: Um, over the last year. And so while our overall business is doubling, channel is accelerating even, you know, even more. [00:07:02] Cyril Belikoff: And so there, there’s a need from our customers because they buy from our channel and there’s obviously a need from the channel. And so we created this resale enabled offer. As you mentioned, we, um. We announced private preview in September and launched GA at Ignite. So, you know, uh, November, just before Thanksgiving holiday and retail Enable offer is all about scale and how we connect a, a, an independent software vendor or a software company. [00:07:27] Cyril Belikoff: To authorize a channel partner to resell on their behalf on a particular geography. And then that allows software companies to expand into new markets with very little overhead. And it allows the channel partners to create a set of offerings, not only from one partner, but you might have multiple software companies or applications that you stitch that are together to create an end-to-end customer offering or experience. [00:07:51] Cyril Belikoff: And so we are seeing, we are seeing many to many relationships. So software companies might authorize many resellers, many markets they’re in, for example. Yep. And then resellers, um, they’re, they’re becoming authorized resellers from many software companies so that they can really stitch together, end into end solution. [00:08:09] Cyril Belikoff: And it, we’re loving it and we are getting great feedback. It is early days for our global availability for, uh, re office, which. But we had partners that were literally waiting, um, uh, and waiting for deals. And within the first week there was, they were, uh, processing the, the Oreo deals at, at, at quite large scale already. [00:08:31] Cyril Belikoff: So. We are excited about the feedback that we’re getting. We, as you know, we, we stay close to that feedback and we listen well, um, and adjust from it. So we got more work to do, but, um, it’s a great opportunity for, to connect our, our multiple types of partners, software companies, and resellers. [00:08:48] Vince Menzione: Yeah, I agree. [00:08:49] Vince Menzione: And you know, I talk to a lot of these organizations myself, and there is palpable excitement. In the channel from Distees that were sort of disengaged a couple of years ago, maybe, trying to figure out where they were gonna monetize. And the other way area that’s aligned to this as well is the Ms. P community. [00:09:06] Vince Menzione: So these MSPs are getting bigger and bigger, and organizations like Accenture, Avanade, and ndl. Or becoming MSPs or creating Ms. P practices within their own firms. But there’s even these smaller MSPs, but many of ’em are getting to a billion dollars or more. These were little mom and pop companies years ago, but the customer so needs to have, you know, especially with ai, right? [00:09:27] Vince Menzione: Because we’re in a constant state of evolution right now. I need somebody that can help me on the tooling and then also help me on, you know, getting the tooling to work. And so, uh, we’re seeing a lot of excitement from that. Community, which wasn’t really as engaged with Microsoft the way they that they are now. [00:09:43] Vince Menzione: They’re really getting engaged in a big way. [00:09:46] Cyril Belikoff: Yeah, it’s promising. Like you say, you know, the, the, we’re all learning this new AI world and obviously marketplace has taken off. We’ve had the classic SaaS solutions or cloud solutions on marketplace for a while, but really un having the local partner that’s close to the customer, what the customer’s trying to need to do and be able to connect the, the traditional. [00:10:07] Cyril Belikoff: Software as a service applications with these new AI experiences and really, uh, stitch them together and help them operationalize, you know, in their own, you know, cus in their own terms and what they’re trying to, uh, do is so important. You know, um, and to your point there, there are large, they’re the large ones that are seeing opportunity on the marketplace. [00:10:27] Cyril Belikoff: But the, you know, when you get down to, uh, medium and smaller businesses, they really need their local friendly resetter to help them. [00:10:35] Vince Menzione: Yeah. [00:10:35] Cyril Belikoff: Uh, so you’re right. We are seeing an, a new en energy engagement from not only our existing 500,000 partners, but a bunch of those new ones. [00:10:44] Vince Menzione: So, uh, again, second week of 2026, and people are really just starting to wake up from the holidays. [00:10:50] Vince Menzione: Now they’re getting ready for their s ks. All these partners are lining up and getting their teams aligned. Uh, you’re in front of them. Let’s have a conversation like what should they be doing better and differently? What do they need to go do now? It’s 2026. [00:11:06] Cyril Belikoff: Yeah. Um, you know, first of all, if you’re a software company, you know, understand what the, the Microsoft marketplace can help you with, uh, can help you scale to global markets, remove burdens like tax, um, a processing, engaging with customers. [00:11:21] Cyril Belikoff: Um, we’re seeing an acceleration and doubling of, uh, not an acceleration deals, but doubling of deal sizes, as you know, through the marketplace. Uh, and there. It helps with engagement at different types of companies, whether it’s, or different types of, uh, roles in a company, whether it’s a, a procurement person or an IT person or a business person. [00:11:42] Cyril Belikoff: So, you know, get onto the marketplace, create offerings, um, and give us feedback. And then on the reseller side, um, also lots of opportunities, you know, register as, as a reseller, um, you know, understand the benefits and. The, the Azure sponsorships that we have available for you, that you can close deals with their, their, their credits and, and incentives that we provide to you. [00:12:06] Cyril Belikoff: And then figure out how you do your first deal with a software company. Um, yeah. You know, a lot of people will say like, should I have a big strategy? And Yeah. Yeah. I mean, if you want to, that’s okay, but just getting into. Uh, the marketplace, figuring out one or two deals, transacting and seeing the opportunity is many ways the best way to do it and to learn it yourself. [00:12:28] Cyril Belikoff: And then you figure out, okay, where, where’s the opportunity for me in this deal? Am I in the transaction? Uh, am I in the services around the transaction or combination? Um, and just getting your feet wet will get you going and, and, uh, get you learning. [00:12:42] Vince Menzione: You know, I think about this in the, the time the partners are, they have this huge opportunity with Microsoft around marketplace and then thinking about how they build their own ecosystem. [00:12:52] Vince Menzione: And like you said, don’t, don’t try and boil the ocean, right. Don’t try and do it all at once. Mm-hmm. But start out small, but understand, you know, work with the Microsoft teams, understand how, how co-selling works, how to engage with the, with the Microsoft organization. How to, how to be up on marketplace, how to situationally. [00:13:09] Vince Menzione: You know, Jay and I were talking about this 28 moments and he talked about a deal that started out as an AWS deal, but it wound up a Microsoft deal because NTT and Software one were involved in the in the deal and influencing the customer’s decision process. Right working with Microsoft. And so we just need to be smarter, I think. [00:13:28] Vince Menzione: I think today it’s a very different model than it was 20 years ago when you and I got started in this business. Uh, yeah. And people just really need to go think about this more strategically in how they build this. [00:13:39] Cyril Belikoff: It’s great. I totally agree. Um, like I said, getting your feet wet, understanding the co-sell to your point and, and, and how Microsoft sells. [00:13:48] Cyril Belikoff: Um, and then understand what customers are trying to, you know, get, get, get out of it with their, their Azure commitments and how they can retire their Azure commitments through purchases on marketplace, which in sense them, um, to also work on the marketplace. So you, I think partners will find Microsoft sellers. [00:14:04] Cyril Belikoff: Own compensation, um, incentive to work. We’ll find that customers are incentive to transact on the marketplace. And so just enter that, you know, triangle and, and get engaged and, uh, and learn and then give us feedback. Like, like I’ve mentioned many times with you, we, uh, we take feedback every month from customers and partners in, in forums like this, um, in other forums, and then we evolve and, you know, build out, uh, stronger experiences. [00:14:31] Vince Menzione: Yeah. Cyril, I want to thank you again. So great to have you join us today and, uh, so excited to continue our, our mutual relationship and our beneficial relationship in 2026. So thank you again for everything you do and supporting us. [00:14:45] Cyril Belikoff: Yeah, thank you. Thank you. Happy New Year to yourself and uh, and your community and, uh, thanks so much again. [00:14:50] Cyril Belikoff: Appreciate it. [00:14:50] Vince Menzione: Thank you, Cyril. The Ultimate Partner Winter Retreat is gonna be here in the Boca Studio. This is the third year that we’re gonna be here in Boca. This is always a favorite of our community members, our executive members, our sponsors and speakers. We’ll all be here in the studio, which is a really intimate setting. [00:15:12] Vince Menzione: We can see upwards of 40, 50 people. Uh, we’ll be hosting an incredible dinner at the Boca Resort overlooking the golf course. That’s an incredible property and, uh, we’d love to have you join us. Thank you for being part of the ultimate Partner community, and I hope to see you this year at one of our events. [00:15:30] Vince Menzione: Thank you.

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Learning platforms often drive channel training. But now, AI adds a whole new angle. Find out how to enable partners outside the LMS on this Talented Learning Show podcast! The post Podcast 107: How Can AI Enable Partners Outside the LMS? appeared first on Talented Learning.

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At level 11, the Cleric stops being "the healer" and starts being "the department of cosmic corrections." Need a miracle? You've got it. Need a battlefield reorganized? Also you. Need the DM to quietly reconsider every encounter they prepped? Congratulations: you just prepared Heroes' Feast and learned that your god's job description includes "professional problem solver, part-time artillery, full-time vibe check." Welcome to Cleric 11–20, where your faith is strong, your spell list is irresponsible, and your party suddenly thinks every plan can be solved by "ask the Cleric." Show Notes Episode Overview In this episode of RPGBOT.Podcast, we break down how to build and play a D&D 5e Cleric from levels 11–20, where your character graduates from "durable support" to "divine Swiss Army catastrophe." We cover late-tier class features, high-level spell priorities, feat and gear considerations, and how to stay impactful when the game gets weird (and the monsters start having resumes). What Changes at Levels 11–20 Your spell slots get absurd: 6th–9th level spells aren't just stronger—they change what "a problem" even means. Channel Divinity becomes a resource-management minigame: It's no longer "use it when you remember." It's "use it to control the pace of encounters." Your role expands: You're still support… but also control, emergency reset button, and occasionally the party's primary win condition. Late-Tier Cleric Priorities (The "Don't Waste Your Turn" Checklist) Action economy matters more than ever: high-level combats punish "I guess I cast Cure Wounds." Concentration discipline: pick the concentration spell that wins the fight, then protect it like it owes you money. Defenses scale or you get deleted: AC, saves, and positioning keep your miracles online. High-Level Spell Picks That Define Your Cleric Rather than listing everything, we focus on categories of "spells that win sessions," and how to choose within them: Battlefield control & tempo (deny actions, reshape positioning, force bad choices) Pre-fight power (buffs that make the party feel like they're cheating) Hard counters & problem solvers (condition removal, anti-magic, planar nonsense) Clutch buttons (resets, revives, "nope" spells for when the DM smiles too confidently) Feats, Ability Scores, and "High-Level Practicality" When to cap Wisdom, when to take resilience/defensive feats, and when a utility feat is secretly the MVP. War Caster vs. Resilient (Con) (and why your table's encounter style decides this). The "I'm level 15 and still miss" problem: improving reliability via positioning, spell choice, and save targeting. Gear and Magic Items (What You Want and Why) We talk about item functions instead of shopping lists: Concentration protection Mobility and positioning Defensive layers (AC, saves, resistances) Spellcasting flexibility (extra casts, broadened options, panic buttons) Playing Cleric at Tier 4 Without Becoming a Solo Game High-level Clerics can accidentally steal the spotlight. We discuss: How to enable party hero moments while still being decisive When to solve the plot and when to support the plot How to coordinate with the DM so divine power feels epic, not adversarial Key Takeaways Tier 4 Clerics are not "healers," they're strategists. Healing keeps the party alive; control and prevention win fights. Your best turns usually aren't reactive. Preempt threats with positioning, concentration, and proactive tempo spells. Protect concentration like it's your hit points. You can lose the fight without losing HP if you drop the spell that mattered. Pick one job per encounter and do it violently well. Control, buff, counter, rescue—trying to do all of it in one round leads to "meh" turns. Your spell list is a toolbox—prep is gameplay. The difference between "good Cleric" and "legendary Cleric" is often made at dawn. Don't build only for peak moments. Tier 4 is swingy; build for reliability so you're useful even when the boss is immune to your favorite trick. You can be the party's win condition without being the party's main character. Enable your allies' big turns, then drop the miracle when it counts.  

https://www.youtube.com/watch?v=qADSFo0ab10 Joti Brar: Last week I spoke with Nick Cruse of the Revolutionary Blackout Network (RBN) about the USA's regime-change operation in Iran. What is its true content? How should we understand those on the self-identifying ‘left' who are voicing support for allegedly ‘peaceful, pro-democracy protestors' and denouncing ‘regime violence'? And what is the reality about the Islamic Revolution and Iran's role in the middle east and the wider world that we are not being told? We also talked about the role of social democracy (the Labour party in Britain) in propping up imperialism and tying the working class in the west to their own exploiters via social chauvinism, bribery, and the cooptation of our mass movements. If we want to get free, we are going to have to recognise and remove these traitors in our midst. Subscribe! Donate! Join us in building a bright future for humanity! www.thecommunists.org www.lalkar.org www.redyouth.org Telegram: t.me/thecommunists Twitter: twitter.com/cpgbml Soundcloud: @proletarianradio Rumble: rumble.com/c/theCommunists Odysee: odysee.com/@proletariantv:2 Facebook: www.facebook.com/cpgbml Online Shop: https://shop.thecommunists.org/ Education Program: Each one teach one!: https://thecommunists.org/education-programme/ Join the struggle www.thecommunists.org/join/ Donate: www.thecommunists.org/donate/  

At level 11, the Cleric stops being "the healer" and starts being "the department of cosmic corrections." Need a miracle? You've got it. Need a battlefield reorganized? Also you. Need the DM to quietly reconsider every encounter they prepped? Congratulations: you just prepared Heroes' Feast and learned that your god's job description includes "professional problem solver, part-time artillery, full-time vibe check." Welcome to Cleric 11–20, where your faith is strong, your spell list is irresponsible, and your party suddenly thinks every plan can be solved by "ask the Cleric." Show Notes Episode Overview In this episode of RPGBOT.Podcast, we break down how to build and play a D&D 5e Cleric from levels 11–20, where your character graduates from "durable support" to "divine Swiss Army catastrophe." We cover late-tier class features, high-level spell priorities, feat and gear considerations, and how to stay impactful when the game gets weird (and the monsters start having resumes). What Changes at Levels 11–20 Your spell slots get absurd: 6th–9th level spells aren't just stronger—they change what "a problem" even means. Channel Divinity becomes a resource-management minigame: It's no longer "use it when you remember." It's "use it to control the pace of encounters." Your role expands: You're still support… but also control, emergency reset button, and occasionally the party's primary win condition. Late-Tier Cleric Priorities (The "Don't Waste Your Turn" Checklist) Action economy matters more than ever: high-level combats punish "I guess I cast Cure Wounds." Concentration discipline: pick the concentration spell that wins the fight, then protect it like it owes you money. Defenses scale or you get deleted: AC, saves, and positioning keep your miracles online. High-Level Spell Picks That Define Your Cleric Rather than listing everything, we focus on categories of "spells that win sessions," and how to choose within them: Battlefield control & tempo (deny actions, reshape positioning, force bad choices) Pre-fight power (buffs that make the party feel like they're cheating) Hard counters & problem solvers (condition removal, anti-magic, planar nonsense) Clutch buttons (resets, revives, "nope" spells for when the DM smiles too confidently) Feats, Ability Scores, and "High-Level Practicality" When to cap Wisdom, when to take resilience/defensive feats, and when a utility feat is secretly the MVP. War Caster vs. Resilient (Con) (and why your table's encounter style decides this). The "I'm level 15 and still miss" problem: improving reliability via positioning, spell choice, and save targeting. Gear and Magic Items (What You Want and Why) We talk about item functions instead of shopping lists: Concentration protection Mobility and positioning Defensive layers (AC, saves, resistances) Spellcasting flexibility (extra casts, broadened options, panic buttons) Playing Cleric at Tier 4 Without Becoming a Solo Game High-level Clerics can accidentally steal the spotlight. We discuss: How to enable party hero moments while still being decisive When to solve the plot and when to support the plot How to coordinate with the DM so divine power feels epic, not adversarial Key Takeaways Tier 4 Clerics are not "healers," they're strategists. Healing keeps the party alive; control and prevention win fights. Your best turns usually aren't reactive. Preempt threats with positioning, concentration, and proactive tempo spells. Protect concentration like it's your hit points. You can lose the fight without losing HP if you drop the spell that mattered. Pick one job per encounter and do it violently well. Control, buff, counter, rescue—trying to do all of it in one round leads to "meh" turns. Your spell list is a toolbox—prep is gameplay. The difference between "good Cleric" and "legendary Cleric" is often made at dawn. Don't build only for peak moments. Tier 4 is swingy; build for reliability so you're useful even when the boss is immune to your favorite trick. You can be the party's win condition without being the party's main character. Enable your allies' big turns, then drop the miracle when it counts.  

The Paveway bomb, invented by Texas Instruments in the 1970s, was the first truly precise munition.  It revolutionized America's air campaign in Vietnam and allowed whole new kinds of “limited” U.S. wars in Libya, Iraq, Serbia, and beyond.But Paveway's true legacy was psychological: it seduced generations of U.S. leaders into believing that tactical precision creates strategic victories with few costs.Jeff Stern, an intrepid chronicler of modern conflict, tells this story in his new book The Warhead: The Quest to Build the Perfect Weapon in the Age of Modern Warfare.  He joins Jon Bateman on The World Unpacked to explore the past, present, and future of precision warfare. 

In this episode of the Epigenetics Podcast, we talked with Peggy Farnham from the Keck School of Medicine at USC about her work on establishing the ChIP Method in mammalian cells. In this episode, we dive into the relationship between transcription factors, chromatin dynamics, and gene expression with Professor Peggy Farnham from the Keck School of Medicine at USC. Professor Farnham shares her profound insights into how her groundbreaking research has reshaped our understanding of gene regulation and its implications in cancer. We explore how she has been a pioneer in mapping the genome-wide landscape of regulatory proteins, illuminating the molecular logic behind transcriptional control and its disruption in cancer biology. The interview starts with her instrumental role in adapting chromatin immunoprecipitation (ChIP) technology from yeast to human cells. Professor Farnham reflects on the technical challenges she faced during this transition, such as the quest for visibility of signals in mammalian systems. Her ability to innovate and troubleshoot challenges led to significant advancements in techniques that allow for the rapid identification of transcription factor binding sites, fundamentally changing the landscape of epigenetic research. As the discussion progresses, we learn about Professor Farnham's active involvement in the ENCODE project, where she contributed to high-resolution mapping of transcription factors and regulatory elements in human cells. She articulates her appreciation for collaborative efforts in science, highlighting how working within a consortium harnesses the collective expertise of diverse research groups. This collaboration not only bolstered the credibility of the data produced but also propelled the field forward in understanding the complexity of gene regulation. Through her participation in various projects, such as the Psyc-ENCODE consortium and the Roadmap Epigenome Mapping Consortium, Professor Farnham shares insights into her investigation of epigenetic variations, particularly in relation to complex disorders like schizophrenia. Her findings underscore the nuances of enhancer variability among individuals and the implications for understanding disease mechanisms, thereby advancing our knowledge of genetic regulation and its contributions to diverse biological outcomes. Moreover, the episode highlights Professor Farnham's reflective understanding of emerging technologies in the field. She discusses the evolution of methods that allow researchers to investigate gene regulation at single-cell resolution, recognizing the significant implications these innovations have for our comprehension of cellular differentiation and the transcriptional landscape. References Weinmann AS, Bartley SM, Zhang T, Zhang MQ, Farnham PJ. Use of chromatin immunoprecipitation to clone novel E2F target promoters. Molecular and Cellular Biology. 2001 Oct;21(20):6820-6832. DOI: 10.1128/mcb.21.20.6820-6832.2001. PMID: 11564866; PMCID: PMC99859. Wells J, Farnham PJ. Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. Methods (San Diego, Calif.). 2002 Jan;26(1):48-56. DOI: 10.1016/s1046-2023(02)00007-5. PMID: 12054904. Rhie SK, Schreiner S, Witt H, et al. Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation. Science Advances. 2018 Dec;4(12):eaav8550. DOI: 10.1126/sciadv.aav8550. PMID: 30555922; PMCID: PMC6292713. Tak YG, Hung Y, Yao L, et al. Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells. Nucleic Acids Research. 2016 May;44(9):4123-4133. DOI: 10.1093/nar/gkv1530. PMID: 26743005; PMCID: PMC4872074. Related Episodes The Effect of lncRNAs on Chromatin and Gene Regulation (John Rinn) CpG Islands, DNA Methylation, and Disease (Sir Adrian Bird) The Future of Protein–DNA Mapping (Mitch Guttman) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

In this episode of WP Tavern, Nathan Wrigley chats with Charly Leetham about her journey as a digital nomad using WordPress. Charly shares how evolving technology allowed her to build a flexible, location-independent tech support business. She discusses the freedoms and challenges of living on the road, remote work essentials like Starlink for internet access, and how she supports clients with their tech and websites. The conversation highlights both practical insights and the personal rewards of a nomadic, tech-enabled lifestyle. If you've ever imagined trading your desk for the open road, or wondered what's technologically and personally possible as a remote WordPress worker, this episode is for you.

In this episode of WP Tavern, Nathan Wrigley chats with Charly Leetham about her journey as a digital nomad using WordPress. Charly shares how evolving technology allowed her to build a flexible, location-independent tech support business. She discusses the freedoms and challenges of living on the road, remote work essentials like Starlink for internet access, and how she supports clients with their tech and websites. The conversation highlights both practical insights and the personal rewards of a nomadic, tech-enabled lifestyle. If you've ever imagined trading your desk for the open road, or wondered what's technologically and personally possible as a remote WordPress worker, this episode is for you.

FaZe ZooMaa, Ben, Aches, Parasite, Octane, and Enable break down the Call of Duty League matches from 1/25/2026

Life can sometimes be overwhelming, and balancing all the competing demands we face can be a challenge. But God desires to give you a supernatural strength that only He can give. In this series, The Power of God, Pastor Chappell offers biblical insight and simple steps that can take you from where you are to where you want to be. As you apply the truth of God's Word, your life will change in ways you never thought possible.

On today's MadTech Daily, we look at TikTok splitting its US app from its global business, YouTube CTV ads enabling shopping, and Netflix doubling ad revenue while eyeing growth in 2026.

Life can sometimes be overwhelming, and balancing all the competing demands we face can be a challenge. But God desires to give you a supernatural strength that only He can give. In this series, The Power of God, Pastor Chappell offers biblical insight and simple steps that can take you from where you are to where you want to be. As you apply the truth of God's Word, your life will change in ways you never thought possible.

FaZe ZooMaa, Parasite, Benj, Octane, and Enable break down the Call of Duty League matches from 1/23/2026!

FaZe ZooMaa, Benj, Parasite, Temp, and Enable break down the Call of Duty League matches from 1/17/2026!

FaZe ZooMaa, Temp, Parasite, Enable, and Octane break down the Call of Duty matches from 1/16/2026!

What if the friction stopping crypto adoption is the same fear that kept 62% of US adults from making their first online purchase until the pandemic forced them? From Bitcoin at $2 to NFTs that people still don't understand, the pattern repeats: revolutionary technology stumbles not on innovation, but on trust and usability.This encore episode (originally published in April 2024 and our #1 most downloaded episode of the year) brings back Jean-Louis Hé, Director of Digital and E-Commerce at Yves Saint Laurent Beauty. Join hosts Chuck Moxley and Nick Paladino as they reflect on how quickly technology moves, blockchain was the emerging tech buzz in 2024, now AI dominates every conversation.Jean-Louis shares his journey from wanting to be an architect to shaping digital experiences, explaining how his family's Chinese restaurant in Paris taught him the importance of human connection that now informs his work bridging physical retail with digital innovation. He reveals YSL's Web3 experiments with Beauty Blocks NFTs designed to transform one-way brand communication into participatory community building, drawing parallels to Nike's success letting customers co-design shoes. We tackle the massive friction barriers in crypto (MetaMask wallets, scam airdrops, ledger codes, obscure coin exchanges), explore why connected mirrors and QR codes still matter in stores, and examine how gaming revolutionized technology infrastructure that business now benefits from. Jean-Louis argues the biggest misconception about frictionless digital experiences is thinking you only need to optimize the digital interface, when the real work is crafting a cohesive story across the entire consumer journey.Key Actionable Takeaways:Design for the complete journey, not just digital touchpoints - A beautiful website won't succeed if it's disconnected from physical stores, marketplace channels, and brand values across the customer experienceBuild two-way participation instead of one-way communication - Enable consumers to co-create through challenges, exclusive access, and design input rather than passively consuming brand messagesRecognize adoption friction mirrors historical technology fears - The same resistance to online credit cards 15 years ago now appears with crypto wallets; reduce friction by simplifying onboarding and building trust through educationWant more tips and strategies about creating frictionless digital experiences? Subscribe to our newsletter! https://www.thefrictionlessexperience.com/frictionless/Download the Five Step Site Speed Target Playbook: http://bluetriangle.com/playbookJean-Louis's LinkedIn: https://www.linkedin.com/in/jeanlouishe/ Nick Paladino's LinkedIn: https://linkedin.com/in/npaladino Chuck Moxley's LinkedIn: https://www.linkedin.com/in/chuckmoxley/Chapters:(00:00) Introduction(01:00) Blockchain vs AI adoption(02:30) Jean-Louis's origin story(06:00) Architecture meets UX(08:00) PowerPoint wireframes era(10:00) Growing up in analog retail(11:30) Connected retail tools(13:00) McDonald's efficiency principles(14:00) Digital apron concept(15:00) Selling fragrance online(16:00) Brain signal scent tech(18:00) Beyond screen interfaces(19:30) Crypto and NFT curiosity(21:00) Web3 and user control(23:47) Bitcoin at $2 regrets(26:00) YSL Beauty Blocks launch(27:00) Nike's community building(29:00) Crypto wallet friction(31:30) Early e-commerce parallels(32:00) Buying obscure coins(34:00) Twitter crypto scams(35:30) Pandemic online shopping(37:45) Biggest misconception(40:00) Human connection matters(41:00) The phygital world(42:00) Immersive web evolution(44:00) Gaming drives innovation(45:30) Roblox brand strategy(47:00) Digital ownership economics(48:00) Conclusion

The Legislature put out their own budget. It is better than MLG's (including not funding universal free childcare): https://errorsofenchantment.com/a-few-positives-relative-to-mlgs-in-the-lfc-budget/ More detail on plans for free child care scandal in MN (Biden rule change allowed reimbursement based on "enrollment" as opposed to actual attendance): https://errorsofenchantment.com/mlgs-plans-for-free-childcare-plus-a-biden-era-rule-allowed-child-care-centers-to-be-paid-on-enrollment-not-attendance/ MLG and the Legislature are spending $30 million on a "literacy center" in ABQ: https://errorsofenchantment.com/mlg-when-in-doubt-spend-more-money/ New Mexico was named the worst state in the nation to raise a family by Wallethub: https://wallethub.com/edu/best-states-to-raise-a-family/31065 Rail Runner ridership remains at its depressed "new normal" level while emitting more CO2 than cars being driven to Santa Fe: https://errorsofenchantment.com/the-new-normal-railrunner-ridership-has-leveled-off-at-a-new-lower-level-than-before-covid/ Sen. Jeff Steinborn has introduced an anti-data center bill.

In this Omni Talk Retail episode, recorded live from NRF 2026 in the Vusion podcast studio, Mark Propes from Vusion and Art Miller from Qualcomm reveal how their partnership is enabling "detect and connect" capabilities that transform physical retail into personalized experiences, and why retailers still testing need to operationalize now before the gap becomes permanent. From edge computing that processes 4K video locally instead of streaming to the cloud, to closed-loop attribution tracking customer intent in real-time physical space, Mark and Art break down the multimodal signal taxonomy (RFID, Wi-Fi, Bluetooth, vision) powering connected stores. They share insights on why scanning barcodes continuously creates data-poor environments, how agentic AI creates new doorways into physical stores, and the precision needed for sub-30 minute delivery promises. If you've wondered what detect and connect actually means beyond buzzwords, this conversation delivers the technical foundation and business applications.

FaZe ZooMaa, Octane, Aches, BenJNissim, and Enable break down the Call of Duty League matches from 1/10/2026!Like, comment, subscribe!

FaZe ZooMaa, Octane, Parasite, Temp, and Enable break down the Call of Duty League matches from 1/9/2026!

Send us a textIn this episode of WTR Small-Cap Spotlight, host Tim Gerdeman and analyst Robert Sassoon speak with Eric Poma PhD, CEO of Calidi Biotherapeutics Inc (NYSE American: CLDI).  The discussion focuses on how Calidi is solving the "delivery problem" in cancer treatment, and specifically how to transport cancer-killing oncolytic viruses systemically through the bloodstream without the body's immune system neutralizing them before they reach the tumor.

Topics covered in this episode: ty: An extremely fast Python type checker and LSP Python Supply Chain Security Made Easy typing_extensions MI6 chief: We'll be as fluent in Python as we are in Russian Extras Joke Watch on YouTube About the show Connect with the hosts Michael: @mkennedy@fosstodon.org / @mkennedy.codes (bsky) Brian: @brianokken@fosstodon.org / @brianokken.bsky.social Show: @pythonbytes@fosstodon.org / @pythonbytes.fm (bsky) Join us on YouTube at pythonbytes.fm/live to be part of the audience. Usually Monday at 10am PT. Older video versions available there too. Finally, if you want an artisanal, hand-crafted digest of every week of the show notes in email form? Add your name and email to our friends of the show list, we'll never share it. Brian #1: ty: An extremely fast Python type checker and LSP Charlie Marsh announced the Beta release of ty on Dec 16 “designed as an alternative to tools like mypy, Pyright, and Pylance.” Extremely fast even from first run Successive runs are incremental, only rerunning necessary computations as a user edits a file or function. This allows live updates. Includes nice visual diagnostics much like color enhanced tracebacks Extensive configuration control Nice for if you want to gradually fix warnings from ty for a project Also released a nice VSCode (or Cursor) extension Check the docs. There are lots of features. Also a note about disabling the default language server (or disabling ty's language server) so you don't have 2 running Michael #2: Python Supply Chain Security Made Easy We know about supply chain security issues, but what can you do? Typosquatting (not great) Github/PyPI account take-overs (very bad) Enter pip-audit. Run it in two ways: Against your installed dependencies in current venv As a proper unit test (so when running pytest or CI/CD). Let others find out first, wait a week on all dependency updates: uv pip compile requirements.piptools --upgrade --output-file requirements.txt --exclude-newer "1 week" Follow up article: DevOps Python Supply Chain Security Create a dedicated Docker image for testing dependencies with pip-audit in isolation before installing them into your venv. Run pip-compile / uv lock --upgrade to generate the new lock file Test in a ephemeral pip-audit optimized Docker container Only then if things pass, uv pip install / uv sync Add a dedicated Docker image build step that fails the docker build step if a vulnerable package is found. Brian #3: typing_extensions Kind of a followup on the deprecation warning topic we were talking about in December. prioinv on Mastodon notified us that the project typing-extensions includes it as part of the backport set. The warnings.deprecated decorator is new to Python 3.13, but with typing-extensions, you can use it in previous versions. But typing_extesions is way cooler than just that. The module serves 2 purposes: Enable use of new type system features on older Python versions. Enable experimentation with type system features proposed in new PEPs before they are accepted and added to the typing module. So cool. There's a lot of features here. I'm hoping it allows someone to use the latest typing syntax across multiple Python versions. I'm “tentatively” excited. But I'm bracing for someone to tell me why it's not a silver bullet. Michael #4: MI6 chief: We'll be as fluent in Python as we are in Russian "Advances in artificial intelligence, biotechnology and quantum computing are not only revolutionizing economies but rewriting the reality of conflict, as they 'converge' to create science fiction-like tools,” said new MI6 chief Blaise Metreweli. She focused mainly on threats from Russia, the country is "testing us in the grey zone with tactics that are just below the threshold of war.” This demands what she called "mastery of technology" across the service, with officers required to become "as comfortable with lines of code as we are with human sources, as fluent in Python as we are in multiple other languages." Recruitment will target linguists, data scientists, engineers, and technologists alike. Extras Brian: Next chapter of Lean TDD being released today, Finding Waste in TDD Still going to attempt a Jan 31 deadline for first draft of book. That really doesn't seem like enough time, but I'm optimistic. SteamDeck is not helping me find time to write But I very much appreciate the gift from my fam Send me game suggestions on Mastodon or Bluesky. I'd love to hear what you all are playing. Michael: Astral has announced the Beta release of ty, which they say they are "ready to recommend to motivated users for production use." Blog post Release page Reuven Lerner has a video series on Pandas 3 Joke: Error Handling in the age of AI Play on the inversion of JavaScript the Good Parts