Podcasts about 6R

Since settling in Cyprus this August, I have been trying to get motivated to work on the podcast again. But OMG so much has changed since we last talked! Including the tools I used to make the show, so bare with me for this episode while I relearn everything. I went to Italy recently to celebrate my anniversary, so what better time than now to dip the toes back into this medium? My partner in thrift crimes, and life, Marsh, decided to interview me about what makes Rome and other hotspots in Italy so great for thrifters and vintage collectors. In this episode I share with you my favorite thrift shops, flea markets, and places to visit in one of the most gorgeous countries in all of Europe. Be sure and save this episode when planning your Italian vacation so you can hit up all best secondhand spots we discussed here. For show notes, visit the website www.thrifttherapypod.com Follow along with my global thrifting adventures and travel ootds @thrifthterapystyle on Instagram and TikTok Social Media LINKS https://www.thrifttherapypod.com/ https://www.instagram.com/thrifttherapystyle/  (Me) https://www.instagram.com/gnomefloof/  (Marsh) https://twitter.com/thrifttherapy https://www.tiktok.com/@thrifttherapystyle Rome Spots Humana Vintage Travestere, Via della Scala, 13, 00153 Roma RM, Italy Humana Vintage Roma (1) Via Cavour, 102, 00184 Roma RM, Italy Humana Vintage 2, Corso Vittorio Emanuele II, 199, 00186 Roma RM, Italy Weekday Flea Market Via Sannio Flea Market, Via Sannio, 00183 Roma RM, Italy Sunday Flea Market, Porta Portese, Piazza di Porta Portese, 00153 Roma RM, Italy Florence Spots Humana Vintage Firenze Via delle Belle Donne, 4/6R, 50123 Firenze FI, Italy Tartan Vintage Via dei Palchetti, 5/5a, 50123 Firenze FI, Italy Street Doing Vintage Couture Via dei Servi, 88/r, 50122 Firenze FI, Italy Giratempo Vintage store Firenze Piazzetta Piero Calamandrei, 2, 50122 Firenze FI, Italy --- Support this podcast: https://podcasters.spotify.com/pod/show/thrifttherapy/support

Join Mike and Jamison as they cover one of the foundations of sustainability, the 6R's. Sometimes they agree and other times they don't but all of the time it's fun! --- Support this podcast: https://podcasters.spotify.com/pod/show/realistic-sustainability/support

TOP 3 narzędzia skutecznego lidera to 6R, Runners-Repeaters-Strangers i Boardmeetingi. https://bit.ly/konsultacja_bezplatna Skuteczny lider nie improwizuje, buduje poczucie przynależności, zdolność do adaptacji, zarządza w oparciu o fakty. Tworzy angażujące środowisko, w którym wszyscy mają wspólne cele i nikt niczego nie musi się domyślać. Im częściej zespół sprawdza, jak im idzie, tym częściej mogą to poprawiać. Szczegóły w tym odcinku.  7 aspektów świadomego przywództwa:  Ludzie potrzebują przynależećBycie liderem to przywilej i odpowiedzialność Liderzy nie powinni improwizować Leadership to połączenie empatii i efektywności Efektywne procesy to zarządzanie oparte na faktach Kwestionowanie status quo daje ponadprzeciętną zdolność do adaptacji ]Trzy najbardziej skuteczne narzędzia do budowania efektywnego, zaangażowanego i zdolnego do adaptacji zespołu: 6R, Runners-Repeaters-Strangers, Boardmeetingi realizowane w formule Cel-Wynik-Kaizen __________________________Polecane w tym odcinku:    YOUNIVERSITYNa naszej streamingowej platformie rozwojowej liderzy znajdą wszystko, co jest potrzebne, by tworzyć angażujące, efektywne środowisko pracy. Wypróbuj 3 dni za darmo: https://bit.ly/youniversity_    BEZPŁATNA KONSULTACJANatomiast tych z Was, którzy są zainteresowani przeprowadzaniem transformacji, budowaniem przywództwa, w którym ludzie zdejmują z zarządów odpowiedzialność za Run the Business, a zarządy mogą skupić się na realizacji strategii, to zapraszam do kontaktu bezpośrednio ze mną: r.drzewiecki@leanpassion.pl lub poprzez formularz zamówienia bezpłatnej konsultacji: https://bit.ly/konsultacja_bezplatna  Robimy około 70 transformacji rocznie, jesteśmy skuteczni, bierzemy odpowiedzialność za to, że wyniki są i że są trwałe.Radek Drzewiecki

Welcome to the January 2024 Meaningful Leader. In this episode I talk about: How do I create a culture of innovation? | To get your best ideas, try really hard not to think | The George Costanza: Do The Opposite | Can you be comfortable with your ignorance?   Read more about the 6R's in this article   The Meaningful Leader is a bite-sized disruption that gives insight into challenges other leaders are facing, the latest tools to tackle turbulence, and inputs to innovate your leadership.

Nghe trọn nội dung sách nói Cuộc Khủng Hoảng Kế Tiếp trên ứng dụng Voiz FM: https://voiz.vn/play/2035 “Cuộc khủng hoảng kế tiếp – các bài học quý báu quản trị bình thường mới” là cuốn sách thứ hai của tác giả Mã Thanh Danh nhằm giúp doanh nghiệp vượt qua và chinh phục cơn hoảng loạn. Cuốn sách được ấp ủ sau hai năm toàn thế giới phải đối mặt với đại dịch đã đúc kết kinh nghiệm của tác giả ở vai trò một chuyên gia tư vấn về quản trị rủi ro, kết hợp với những phương pháp thực tế mà các doanh nghiệp chiến thắng khủng hoảng đã và đang thực hiện. Với triết lý “Sự thay đổi không quan trọng, quan trọng là nhìn ra NGUY và CƠ để thực sự thay đổi”, tác giả đã thổi vào cuốn sách một làn sóng tư tưởng mới – các doanh nghiệp cần tìm ra vaccine cho chính mình để được tái sinh. Cùng với đó, công cụ 6R mà tác giả mang tới trong cuốn sách sẽ là phương thuốc hữu hiệu giúp doanh nghiệp THỰC SỰ THAY ĐỔI, ít bị ảnh hưởng bởi những rủi ro bất định. Đây được coi là cuốn cẩm nang cho doanh nghiệp để quản trị rủi ro trong Bình Thường Mới – bằng một phương pháp Mới hơn Bình Thường rất nhiều! Triết lý cuốn sách: • Sự thay đổi không quan trọng, quan trọng là nhìn ra NGUY và CƠ để THỰC SỰ THAY ĐỔI. Đối tượng độc giả: • Doanh nhân, chủ doanh nghiệp vừa và nhỏ • Người mới khởi nghiệp Tại ứng dụng sách nói Voiz FM, sách nói Cuộc Khủng Hoảng Kế Tiếp được đầu tư chất lượng âm thanh và thu âm chuyên nghiệp, tốt nhất để mang lại trải nghiệm nghe tuyệt vời cho bạn. --- Về Voiz FM: Voiz FM là ứng dụng sách nói podcast ra mắt thị trường công nghệ từ năm 2019. Với gần 2000 tựa sách độc quyền, Voiz FM hiện đang là nền tảng sách nói podcast bản quyền hàng đầu Việt Nam. Bạn có thể trải nghiệm miễn phí đa dạng nội dung tại Voiz FM từ sách nói, podcast đến truyện nói, sách tóm tắt và nội dung dành cho thiếu nhi. --- Voiz FM website: https://voiz.vn/ Theo dõi Facebook Voiz FM: https://www.facebook.com/VoizFM Tham khảo thêm các bài viết review, tổng hợp, gợi ý sách để lựa chọn sách nói dễ dàng hơn tại trang Blog Voiz FM: http://blog.voiz.vn/ --- Cảm ơn bạn đã ủng hộ Voiz FM. Nếu bạn yêu thích sách nói Cuộc Khủng Hoảng Kế Tiếp và các nội dung sách nói podcast khác, hãy đăng ký kênh để nhận thông báo về những nội dung mới nhất của Voiz FM channel nhé. Ngoài ra, bạn có thể nghe BẢN FULL ĐỘC QUYỀN hàng chục ngàn nội dung Chất lượng cao khác tại ứng dụng Voiz FM. Tải ứng dụng Voiz FM: voiz.vn/download #voizfm #sáchnói #podcast #sáchnóiCuộcKhủngHoảngKếTiếp #MãThanhDanh

Mark finishes the year with some reflections on highlights, challenges, the questions he was asked most, and his 'gift' to you is an opportunity to embrace what he calls 'The 6R's' as you steam off into 2024. Before you get into 2024 'busy fool' mode have a crack at your own 6R's Checklist/Reflect list and keep yourself accountable and on track for a ripping year. Click the link here to access the editable PDF: https://marklebusque.com/wp-content/uploads/2023/12/6RChecklist-Reflectlist.pdfhttps://bit.ly/6RChecklist-Reflectlist Thanks all for supporting the SPH Poddy and see you in 2024.

Martes de la XXX semana del Tiempo ordinarioLectionary: 480Primera lecturaRom 8, 18-25Hermanos: Considero que los sufrimientos de esta vida no se pueden comparar con la gloria que un día se manifestará en nosotros; porque toda la creación espera, con seguridad e impaciencia, la revelación de esa gloria de los hijos de Dios.La creación está ahora sometida al desorden, no por su querer, sino por voluntad de aquel que la sometió, pero dándole al mismo tiempo esta esperanza: que también ella misma va a ser liberada de la esclavitud de la corrupción, para compartir la gloriosa libertad de los hijos de Dios.Sabemos, en efecto, que la creación entera gime hasta el presente y sufre dolores de parto; y no sólo ella, sino también nosotros, los que poseemos las primicias del Espíritu, gemimos interiormente, anhelando que se realice plenamente nuestra condición de hijos de Dios, la redención de nuestro cuerpo.Porque ya es nuestra la salvación, pero su plenitud es todavía objeto de esperanza. Esperar lo que ya se posee no es tener esperanza, porque, ¿cómo se puede esperar lo que ya se posee? En cambio, si esperamos algo que todavía no poseemos, tenemos que esperarlo con paciencia.Salmo ResponsorialSalmo 125, 1-2ab. 2cd-3. 4-5. 6R. Grandes cosas ha hecho por nosotros, Señor.Cuando el Señor nos hizo volver del cautiverio,creíamos soñar;entonces no cesaba de reír nuestra bocani se cansaba entonces la lengua de cantar.R. Grandes cosas has hecho por nosotros, Señor.Aun los mismos paganos con asombro decían:"¡Grandes cosas ha hecho por ellos el Señor!"Y estábamos alegres,pues ha hecho grandes cosas por su pueblo el Señor.R. Grandes cosas has hecho por nosotros, Señor.Como cambian los ríos la suerte del desierto,cambia también ahora nuestra suerte, Señor,y entre gritos de júbilocosecharán aquellos que siembran con dolor.R. Grandes cosas has hecho por nosotros, Señor.Al ir, iba llorando, cargando la semilla;al regresar, cantando vendrán con sus gavillas.R. Grandes cosas has hecho por nosotros, Señor.Aclamación antes del EvangelioCfr Mt 11, 25R. Aleluya, aleluya.Te doy gracias, Padre, Señor del cielo y de la tierra,porque has revelado los misterios del Reinoa la gente sencilla.R. Aleluya.EvangelioLc 13, 18-21En aquel tiempo, Jesús dijo: "¿A qué se parece el Reino de Dios? ¿Con qué podré compararlo? Se parece a la semilla de mostaza que un hombre sembró en su huerta; creció y se convirtió en un arbusto grande y los pájaros anidaron en sus ramas".Y dijo de nuevo: "¿Con qué podré comparar al Reino de Dios? Con la levadura que una mujer mezcla con tres medidas de harina y que hace fermentar toda la masa".

In this episode I am once again joined by David Johnson, a meditation teacher and author of ‘A Path to Nibbana'. In this episode David describes the forgiveness meditation technique that he teaches to his students who encounter emotional blocks in meditation practice. David recalls his own journey with forgiveness, including his experience forgiving a toxic boss, and shares his students' accounts using this technique. David also explains the links between keeping Buddhist precepts and a peaceful mind, and details other benefits of a moral life, including increase in personal power and acquisition of siddhi. … Video version: https://www.guruviking.com/podcast/ep225-forgiveness-meditation-david-johnson-2 Also available on Youtube, iTunes, & Spotify – search ‘Guru Viking Podcast'. … Topics Include: 00:00 - Intro 00:47 - Dealing with emotional blocks in meditation 01:47 - Metta vs breath as meditation object 02:37 - Advantages of metta meditation 03:16 - Emotional and psychological blocks to feeling good 04:20 - When the 6R's aren't enough 05:55 - The process of forgiveness 07:32 - How to forgive 08:47 - Don't dredge the mind 10:09 - How David forgave his toxic boss 13:19 - Anecdotes of students' forgiveness 17:51 - The power of the habit of forgiveness 19:27 - Phrases to unlock forgiveness 20:38 - A common metta meditation mistake 24:11 - The Buddha's forgiveness method 25:19 - Meditation dosage 27:17 - David on psychiatry and therapy 31:22 - When to stop the technique 32:55 - Will forgiveness make me a pushover? 35:44 - Developing personal power 36:33 - David's fears 37:30 - The root of fear 43:01 - Why keep the precepts 42:22 - How negative karma ripens 44:55 - Benefits of following the precepts 48:33 - Investing virtue for positive rewards … Previous episode with David Johnson: - https://www.guruviking.com/podcast/ep212-path-to-nibbna-david-johnson To find our more about David Johnson visit: - https://www.dhammasukha.org/forgiveness-meditation - https://www.dhammasukha.org/david-johnson For more interviews, videos, and more visit: - https://www.guruviking.com Music ‘Deva Dasi' by Steve James

In this episode of Mike and Ron: Here to Help podcast you join your heroes discussing everything from Trump killing Democracy and Republicans being in a post fact society (AGAIN) btu this time it's going to make sure you VOTE in EVERY Election, Americans being civic minded, being able to listen to and debate others opinions healthily and our opinions on Hasan Minhaj lying in his jokes and maybe that's why they're not funny, how Jay Leno isn't hungry for stand up anymore but George Wallace is to the many many ways Ron uses the Mutha F*&6R so eloquently and much more! Don't forget to Subscribe to our Podcast here, and follow us at: @mikesasson & @ronbushofficial on Instagram and @mikeandronheretohelp on Youtube.

Listen to SBS Sinhala Radio's discussion on how to reduce waste in your bin with the 6R method, which is the main theme of Keep Australia Beautiful Week running from 07 - 13 August 2023. - අගෝස්තු 07 - 13 අතර ක්‍රියාත්මක Keep Australia Beautiful Week හි ප්‍රධාන තේමාව වන 6R ක්‍රමය හරහා ඔබේ bin එකේ අපද්‍රව්‍ය අඩු කරගන්නේ කෙසේද යන්න පිළිබඳ SBS සිංහල ගුවන් විදුලිය සිදුකළ සාකච්ඡාවට සවන්දෙන්න.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.08.03.551808v1?rss=1 Authors: Ribeiro, F. C., Cozachenco, D., Argyrousi, E. K., Staniszewski, A., Wiebe, S., Calixtro, J. D., Soares-Neto, R., Al-Chami, A., El Sayegh, F., Bermudez, S., Arsenault, E., Cossenza, M., Lacaille, J.-C., Nader, K., Sun, H., De Felice, F. G., Lourenco, M. V., Arancio, O., Aguilar-Valles, A., Sonenberg, N., Ferreira, S. T. Abstract: Impaired synaptic plasticity and progressive memory deficits are major hallmarks of Alzheimer's disease (AD). Hippocampal mRNA translation, required for memory consolidation, is defective in AD. Here, we show that genetic reduction of the translational repressors, Fragile X messenger ribonucleoprotein (FMRP) or eukaryotic initiation factor 4E (eIF4E)-binding protein 2 (4E-BP2), ameliorated the inhibition of hippocampal protein synthesis and memory impairment induced by AD-linked amyloid-b; oligomers (AbOs) in mice. Furthermore, systemic treatment with (2R,6R)-hydroxynorketamine (HNK), an active metabolite of the antidepressant ketamine, prevented deficits in hippocampal mRNA translation, long-term potentiation (LTP) and memory induced by AbOs in mice. HNK activated hippocampal signaling by extracellular signal-regulated kinase 1/2 (ERK1/2), mechanistic target of rapamycin (mTOR), and p70S6 kinase 1 (S6K1)/ribosomal protein S6 (S6), which promote protein synthesis and synaptic plasticity. S6 phosphorylation instigated by HNK was mediated by mTOR in hippocampal slices, while rescue of hippocampal LTP and memory in HNK-treated AbO-infused mice depended on ERK1/2 and, partially, on mTORC1. Remarkably, treatment with HNK corrected LTP and memory deficits in aged APP/PS1 mice. RNAseq analysis showed that HNK reversed aberrant signaling pathways that are upregulated in APP/PS1 mice, including inflammatory and hormonal responses and programmed cell death. Taken together, our findings demonstrate that upregulation of mRNA translation corrects deficits in hippocampal synaptic plasticity and memory in AD models. The results raise the prospect that HNK could serve as a therapeutic to reverse memory decline in AD. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

David Colebatch, CEO at Tidal.cloud, joins Corey on Screaming in the Cloud to discuss how Tidal is demystifying cloud migration strategy. David and Corey discuss the pros and cons of a hybrid cloud migration strategy, and David reveals the approach that Tidal takes to ensure they're setting their customers up for success. David also discusses the human element to cloud migration initiatives, and how to overcome roadblocks when handling the people side of migrations. Corey and David also expand on all the capabilities cloud migration unlocks, and David explains how that translates to a distributed product team approach.About DavidDavid is the CEO & Founder of Tidal.  Tidal is empowering businesses to transform from traditional on-premises IT-run organizations to lean-agile-cloud powered machines.Links Referenced: Tidal.cloud: https://tidal.cloud Twitter: https://twitter.com/dcolebatch LinkedIn: https://www.linkedin.com/in/davidcolebatch/ TranscriptAnnouncer: Hello, and welcome to Screaming in the Cloud with your host, Chief Cloud Economist at The Duckbill Group, Corey Quinn. This weekly show features conversations with people doing interesting work in the world of cloud, thoughtful commentary on the state of the technical world, and ridiculous titles for which Corey refuses to apologize. This is Screaming in the Cloud.Corey:  LANs of the late 90's and early 2000's were a magical place to learn about computers, hang out with your friends, and do cool stuff like share files, run websites & game servers, and occasionally bring the whole thing down with some ill-conceived software or network configuration. That's not how things are done anymore, but what if we could have a 90's style LAN experience along with the best parts of the 21st century internet? (Most of which are very hard to find these days.) Tailscale thinks we can, and I'm inclined to agree. With Tailscale I can use trusted identity providers like Google, or Okta, or GitHub to authenticate users, and automatically generate & rotate keys to authenticate devices I've added to my network. I can also share access to those devices with friends and teammates, or tag devices to give my team broader access. And that's the magic of it, your data is protected by the simple yet powerful social dynamics of small groups that you trust.Try now - it's free forever for personal use. I've been using it for almost two years personally, and am moderately annoyed that they haven't attempted to charge me for what's become an essential-to-my-workflow service.Corey: Have you listened to the new season of Traceroute yet? Traceroute is a tech podcast that peels back the layers of the stack to tell the real, human stories about how the inner workings of our digital world affect our lives in ways you may have never thought of before. Listen and follow Traceroute on your favorite platform, or learn more about Traceroute at origins.dev. My thanks to them for sponsoring this ridiculous podcast. Corey: Welcome to Screaming in the Cloud. I'm Corey Quinn. Every once in a while at The Duckbill Group, I like to branch out and try something a little bit different before getting smashed vocally, right back into the box I find myself in for a variety of excellent reasons. One of these areas has been for a while, the idea of working with migrations on getting folks into cloud. There's a lot of cost impact to it, but there's also a lot of things that I generally consider to be unpleasant nonsense with which to deal. My guest today sort of takes a different philosophy to this. David Colebatch is the CEO and founder of Tidal.cloud. David, thank you for joining me.David: Oh, thanks for having me, Corey.Corey: Now, cloud migrations tend to be something that is, I want to say contentious, and for good reason. You have all the cloud providers who are ranting that cloud is the way and the light, as if they've just found religion, and yeah, the fact that it basically turns into a money-printing machine for them has nothing to do with their newfound advocacy for this approach. Now, I do understand that we all have positions that we come from that shape our perspective. You do run and did found a cloud migration company. What's your take on it? Is this as big as the cloud providers say it is, is it overhyped, or is it underhyped?David: I think it's probably in the middle of this stage of the hype cycle. But the reason that that Tidal exists and why I founded it was that many customers were approaching cloud just for cloud's sake, you know, and they were looking at cloud as a place to park VMs. And our philosophy as software engineers at Tidal is that customers were missing out on all the new capabilities that cloud provided, you know, cloud is a new paradigm in compute. And so, our take on it is the customer should not look at cloud as a place to migrate to, but rather as a place to transform to and embrace all the new capabilities that are on offer.Corey: I've been saying for a while that if you sit there and run a total cost analysis for going down the path of a cloud migration, you will not save money in the short term, call it five years or whatnot. So, if you're migrating to the cloud specifically to save money, in the common case, it should be for a capability story, not because it's going to save you money off of what you're currently doing in the data center. Agree, disagree, or it's complicated?David: It's complicated, but you're right in one case: you need to work backwards from the outcomes, I think that much is pretty simple and clear, but many teams overlook that. And again, when you look at cloud for the sake of cloud, you generally do overlook that. But when we work with customers and they log into to our platform, what we find is that they're often articulating their intent as I want to improve business agility, I want to improve staff productivity, and it's less about just moving workloads to the cloud. Anyone can run a VM somewhere. And so, I think, when we work backwards from what the customer is trying to achieve and we look at TCO holistically, not just about how much a computer costs to run and operate in a colo facility, look at it holistically from a staff productivity perspective as well, then the business case for cloud becomes very profound.Corey: I've been saying for a while that I can make a good-faith Total Cost of Ownership analysis—or TCO analysis—in either direction, so tell me what outcome you want and I can come up with a very good-faith effort answer that gives you what you want. I don't think I've seen too many TCO analyses, especially around cloud migrations, that were not justification exercises. They were very rarely open questions. It was, we've decided what we want to do. Now, let's build a business case to do that thing. Agree, disagree?David: [laugh]. Agree. I've seen that. Yeah, we again, like to understand the true picture of total cost of ownership on-premises first, and many customers, depending on who you're engaging with, but on the IT side, might actually shield a few of those costs or they might just not know them. And I'm talking about things like in the facilities, insurance costs, utility bills, and things like that, that might not bubble up.We need to get all those cards on the table in order to conduct a full TCO analysis. And then in the cloud side, we need to look at multiple scenarios per workload. So, we want to understand that lift-and-shift base case that many people come from, but also that transformative migration case which says, I might be running in a server-ful architecture today on-premises, but based on the source code and database analysis that we've done, we can see an easy lift to think like Lambda and serverless frameworks on the cloud. And so, when you take that transformative approach, you may spend some time upfront doing that transformation, or if it's tight fit, it might be really easy; it might actually be faster than reverse-engineering firewall rules and doing a lift-and-shift. And in that case, you can save up to 97% in annual OPEX, which is a huge savings, of course.Corey: You said the magic words, lift-and-shift, which means all right, the gloves come off. Let's have this conversation.David: Oh yeah.Corey: I work on AWS bills for a living. Cloud cost and architecture are fundamentally the same thing, and when I start looking at a company's monthly bill, I can start to see the architectural patterns emerge with no further information than what's shown in the exploded bill view, at least at a high level. It starts to be indicative of different things. And you can generally tell, on some level, when companies have come from a data center environment or at least a data center mentality, in what they've built. And I've talked to a number of companies where they have effectively completely lifted their data center into the cloud and the only real change that they have gotten in terms of value for it has been that machines are going down a lot less because the hard drive failed and they were really bad at replacing hard drives.Now, for companies in that position who have that challenge, yeah, the value is there and it's apparent because I promise, whoever you are, the cloud providers are better at replacing failed hard drives than you are, full stop. And if that's the value proposition you want, great, but it also feels like that is just scratching the surface of what the benefit of cloud providers can be.David: Absolutely. I mean, we look at cloud as a way to unlock new ways of working and it's totally aligned with the new distributed product team approach that many enterprises are pursuing. You know, the rise of Agile and DevOps has sort of facilitated this movement away from single choke points of IT service delivery, like we used to with ITIL, into much more modern ways of working. And so, I imagine when you're looking at those cloud bills, you might see a whole host of workloads centered into one or two accounts, like they've just replicated a data center into one or two accounts and lifted-and-shifted a bunch of EC2 to it. And yeah, that is not the most ideal architectural pattern to follow in the cloud. If you're working backwards from, “I want to improve staff productivity; I want to improve business agility,” you need to do things like limit your blast radius and have a multi-account strategy that supports that.Corey: We've seen this as well and born-in-the-cloud companies, too, because for a long time, that was AWS's guidance of put everything in a single AWS account. The end. And then just, you know, get good with IAM issues. Like, “Well okay, I found that developer environments impacted production.” Then, “Sounds like a skill issue.”Great, but then you also have things that cannot be allocated, like service quotas. When you have something in development run amok and exhaust service quotas for number of EC2 get instance info requests, suddenly, load balancers don't anymore and auto-scaling is kind of aspirational when everything explodes on you. It's the right path, but very often, people got there through following the best advice that AWS offers. I am in the middle of a migration myself from the quote-unquote, “Legacy” AWS account, I built a bunch of stuff in 2016 into its own dedicated account and honestly, it's about as challenging as some data center moves that I've done historically.David: Oh, absolutely. I mean, the cobwebs build up over time and you have a lot of dependencies on services, you completely forget about.Corey: “How do I move this S3 bucket to another account?” “That's the neat part. You don't.”David: [laugh]. We shouldn't just limit that to AWS. I mean, the other cloud providers have similar issues to deal with through their older cloud adoption frameworks which are now playing out. And some of those guidance points were due to technology limitations in the underlying platform, too, and so you know, at the time, that was the best way to go to cloud. But as I think customers have demanded more agility and more control over their blast radiuses and enabling self-service teams, this has forced everyone to sort of come along and embrace this multi-account strategy. Where the challenge is, with a lot of our enterprise clients, and especially in the public—Corey: Embrace it or you'll be made to embrace it.David: Yeah [laugh]. We see with both our enterprise accounts that were early adopters, they certainly have that issue with too much concentration on one or two accounts, but public sector accounts as well, which we're seeing a lot of momentum in, they come from a place where they're heavily regulated and follow heavy architectural standards which dictate some of these things. And so, in order for those clients to be successful in the cloud, they have to have real leadership and real champions that are able to, sort of, forge through some of those issues and break outside of the mold in order to demonstrate success.Corey: On some level, when I see a lift that failed to shift, it's an intentional choice in some cases where the company has decided to improve their data center environment at the cost of their cloud environment. And it feels, on some level, like it's a transitional step, but then it's almost a question that I always have is, was this the grand plan? So, I guess my question for you is, when you see a company that has some workloads in a data center and some living in the cloud provider in what most people call hybrid, is that outcome intentional or is it accidental, where midway through, they realize that some workloads are super hard to migrate? They have a mainframe and there is no AWS/400 available for their use, so they're going to give up halfway, declare victory, and yep we're hybrid now. How did they get there?David: I think it's intentional, quite often that they see hybrid cloud as a stepping stone to going full cloud. And this just comes down to project scoping and governance, too. So, many leaders will draw a ring around the workloads that are easy to migrate and they'll claim success at the end of that and move on to another job quite often. But the visionary leaders will actually chart a path to course that has a hundred percent adoption, full data center closure, off the mainframe, off AS/400, you know, refactored usually, but they'll chart that course at a rate of change that the organization can accept. Because, you know, cloud being a new paradigm, cloud requiring new ways of working, they can't just ram that kind of change through in their enterprise in one or two years; they really need to make sure that it's being absorbed and adopted and embraced by the teams and not alienating the whole company as they go through. And so, I do see it as intentional, but that stepping stone that many companies take is also an okay thing in my mind.Corey: And to be clear, I should bound what I'm saying from the perspective that I'm talking about this from a platonic ideal perspective. I am not suggesting that, “Oh, this thing that you built at your company is crappy,” I mean, any more so than anything else is. I've never yet seen any infrastructure that the people running it would step back and say, “This is amazing and perfect.” Everyone thinks it's a burning dumpster fire of sadness and regret and I'm not entirely sure that they're wrong.I mean, designing an architecture—cloud or otherwise—on a whiteboard is relatively straightforward, for a junior employee, even. The problem is most people don't get to start from scratch and build that thing. There's existing stuff that needs to be migrated in and most of us don't get the luxury of taking two years of downtime for that service while we wind up rebuilding it from scratch. So, it's one of those how do you rebuild a car without taking it off the highway to do it type of questions.David: Well, you want to have a phased migration approach, quite often. Your business can't stop and start because you're doing a migration, so you want to build momentum with the early adopters that are easy to migrate and don't require big interruptions to business. And then for those mission-critical workloads that do need to migrate—and you mentioned mainframe and AS/400 before—they might be areas where you introduce, like, a strangler fig pattern, you know, draw a ring around it, start replicating some services into cloud, and then phase that migration over a year or two, depending on your timeline and scale. And so, we're very much pragmatic in this business that we want to make sure we're doing everything for the right reasons, for the business-led reasons, and fitting in migrations around business objectives and strategies is super critical to success.Corey: What I'm curious about is when we talk about migrations, in fact, when I invited you on the show, and it was like, well, Tidal migrations—one thing I love about calling it that for the domain, in some cases, as well as other things is, “Huh, says right in the tin what it is. Awesome.” But it's migrations, which I assumed to be, you know, from data centers into cloud. That's great. But then you've got the question of, is that what your work looks like? Is it migrations in the other direction? Is cloud repatriation a thing that people are doing, and no one bothered to actually ever bother to demonstrate that to me? Is cloud to cloud? What are you migrating from and to?David: Well, that's great. And we actually dropped migrations from the name.Corey: Oh, my apologies. Events, once again, outpace me.David: Tidal.cloud is our URL and essentially, Corey, the business of migration is something that's only becoming increasingly frequent. Customers are not just migrating from on-premises data centers to cloud, they're also migrating in between their cloud accounts like you are, but also from one cloud provider to another. And our business hypothesis here Tidal is that that innovation cycle is continuing to shrink, and so whereas when I was in the data center automation business, we used to have a 10 and 15-year investment cycle, now customers have embraced continuous delivery of their applications and so there's this huge shift of investment horizons, bringing it down to an almost an annual event for many of the applications that we touch.Corey: You are in fact correct. Tidal.cloud does have a banner at the top that says, “Tidal Migrations is now Tidal.” Yep, you're correct, not that I'm here to like incorrect you on the name of your own company, for God's sake. That's a new level of mansplaining I dare not delve into.But it does say, “Migration made modern,” right at the top, which is great because there's a sense that I've always had that lift-and-shift is poo-pooed as a bad approach to migrating, but I've done it other ways and it becomes disastrous. I've always liked the approach of take something in a data center, migrated into cloud, in the process, changing as few things as possible, and then just get it stable and working there, and step two becomes the transformation because if you try and transform while it moves, yeah, that gets you a little closer to outcome in theory, but when things don't work right—and their computers; let's not kid ourselves, nothing works right—it's a question now of was it my changes? Is it the cloud environment? Is there an unknown dependency that assumes things in the data center that are not true in cloud? It becomes very hard to track down the why of these things.David: There's no one-size-fits-all for migration. It's why we have the seven-hour assessment capabilities. You know, if one application, like you've just talked about, that one application might be better to lift and shift than modernize, there might be real business reasons for doing that. But what we've seen over the years is the customers generally have one migration budget. Now, IT gets one migration budget and they get to end a job in a lift-and-shift scenario and the business says, “Well, what changed? Nothing, my apps still run the same, I don't notice any new capabilities.” And IT then says, “Yeah, yeah. Now, we need the modernization budget to finish.” And they said, “No, no, no. We've just given you a bunch of money. You're not getting any more.”And so, that's what quite often the migrate as a lift-and-shift kind of stalls and you see an exodus of talent out of those organizations, people leave to go on to the next migration project elsewhere and that organization really didn't embrace any of the cloud-native changes that were required. We'd like to really say that—and you saw this on our header—that migrations made modern, we'd like to dispel the myth that you can either migrate or modernize. It's really not an either/or. There's a full spectrum of our methods, like replatform, and refactor, rehosting, in the middle there. And when we work backwards from customers, we want to understand their core objectives for going to cloud, their intent, their, “Why cloud?”We want to understand how it aligns on the cloud value framework, so business agility gains, staff productivity gains, total cost of ownership is important, of course. And then for each of their application workloads, choose the right 6R based on those business outcomes. And it can seem like a complicated or comprehensive problem, but if you automate it like we do, you can get very consistent results very quickly. And that's really the accelerant that we give customers to accelerate their migration to cloud.Corey: One thing that I've noticed—and maybe this makes me cynical—but when I see companies doing lift-and-shift, often they will neglect to do the shift portion of it. Because there's a compelling reason to do a migration to get out of a data center and into a cloud, and often that is a data center contract expiry coming up. But companies are very rarely going to invest the time, energy, and money—which all become the same thing, effectively, at company scale—in refactoring existing applications if they're not already broken.I see that all the time in my work, I don't make recommendations to folks very often have the form, “Oh, just migrate this entire application to serverless and you'll save 80% or more on it.” And it's, “That's great, but that's 18 months' worth of work and it doesn't actually get us closer to our business milestones, so yeah, we're not going to do that.” Cost directly is very rarely a compelling reason to make a migration, but when you're rebuilding something for business purposes, factoring cost concerns into it seems to be a much better way to gain adoption and traction of those ideals.David: Yeah, yeah. Counterpoint on that, when we look at a portfolio of applications, like, hundreds or thousands of applications in an enterprise and we do this type of analysis on them with the customers, what we've learned is that they may refactor and replatform ten, 20% of their workloads, they may rehost 40%, and they'll often turn off the rest, retire them, not migrate them. And many of our enterprise customers that we've spoken to have gone through rationalizations as they've gone to cloud and saved, you know, 59%, just turned off that 59% of an infrastructure, and the apps that they do end up refactoring and modernizing are the ones where either there's a very easy path for them, like, the code is super compatible and written in a way that's fitting with Lambda and so they've done that, or they've got, like you said, business needs coming up. So, the business is already investigating making some changes to the application, they already want to embrace CI/CD pipelines where they haven't today. And for those applications, what we see teams doing is actually building new in the cloud and then managing that as an application migration, like, cutting over that.But in the scheme of an entire portfolio of hundreds or thousands of applications that might be 5, 10, 20% of the portfolio. It won't be all of them. And that's what we say, there's a full spectrum of migration methods and we want to make sure we apply the right ones to each workload.Corey: Yeah, I want to be clear that there are different personas. I find that most of my customers tend to fall into two buckets. The first is that you have the born-in-the-cloud SaaS companies, and that's the world I come from, where you have basically one workload that's 80% of your application spend, your revenue, et cetera. Like, they are not a customer, but take Datadog as an example. Like, the Datadog monitoring application suite would be a good example of this, and then you have a bunch of longtail stuff.Conversely, you've got a large enterprise that might be spending $100 million or so every year, but their largest single application is a couple million bucks because it just has thousands upon thousands of them. And at that point, it becomes much more of a central IT planning problem. In one of those use cases, spending significant effort refactoring and rebuilding things, from an optimization perspective, can pay dividends. In other cases, it tends not to work in quite the same way, just because the economies of scale aren't there. Do you find that most of your customers fall into one of those two buckets? Do you take a different view of the world? How do you see the market?David: Same view, we do. Enterprise customers are generally the areas that we find the most fit with, the ISVs, you know, that have one or two primary applications. Born in the cloud, they don't need to do portfolio assessments. And with the enterprise customers, the central IT bit used to be a blocker and impediment for cloud. We're increasingly seeing more interest from central IT who is trying to lead their organization to cloud, which is great, that's a great sign.But in the past, it had been more of a business-led conversation where one business unit within an enterprise wants to branch away from central IT, and so they take it upon themselves to do an application assessment, they take it upon themselves to get their own cloud accounts, you know, a shadow IT move, in a way. And that had a lot of success because the business would always tie it back to business outcomes that they were trying to achieve. Now, into IT, doing mass migration, mass portfolio assessment, this does require them to engage deeply with the business areas and sometimes we're seeing that happening for the very first time. There's no longer IT at the end of a chain, but rather it's a joint partnership as they go to cloud, which is really cool to see.Corey: When I go to Tidal.cloud, you have a gif—yes, that's how it's pronounced, I'm not going to take debates on that matter—but you have a gif at the top of your site a showing a command line tool that runs an analyze command on an application. What are you looking at to establish an application or workload's suitability for migration? Because I have opinions on this, but you have, you know, a business around this and I'm not going to assume that my strongly-held opinions informed by several weeks of work are going to trump, you know, the thing that your entire company is built around.David: Thanks, Corey. Yeah, you're looking at our command-line utilities there. It's an accompanying part of our product suite. We have a web application and the command-line utilities are what customers use behind their firewall to analyze their applications. The data points that we look at are infrastructure, as you can imagine, you might plug into VMware and discover VMs that are running, we'll look for non-x86 workloads on the network.So, infrastructure is sort of bread and butter; everyone does that. Where Tidal differentiates is going up the stack, analyzing source code, analyzing database technologies, and looking at the schema usage within your on-premises database, for example, which features and functionality are using, and then how that fits to more cloud-native database offerings. And then we'll look at the technology age as well. And when you combine all of those technology factors together, we sort of form a view of what the migration difficulty to cloud will be on various migration outcomes, be it rehost, replatform, or refactor.The other thing that we add there is on the business side and the business intent. So, we want to understand from leadership what their intent is with cloud, and there's some levers they pull in the Tidal platform there. But then we also want to understand from each application owner how they think about their applications, what the value of those applications are to them and what their forward-looking plans are. We capture all these things in our tool, we then run it through our recommendation engine, and that's how we come up with a bespoke migration plan per client.Corey: One of the challenges I have in the cost arena around a lot of these tools that oh, we're going to look at your various infrastructure-as-code situation and see what that's going to cost you for a given change. It's like, sure, that that's not hard from a baseline of I want to spin up ten more EC2 instances. Yes, that is the tricky part of cloud economics known as basic arithmetic. The problem where I see is that okay, and then they're going to run Kubernetes, which has no sense of zone affinity, so it's going to wind up putting nondeterministic amounts of traffic across a AZ boundary and that's going to spike data transfer in some use cases, but none of these tools have any conception as to what those workloads look like. Now, that's a purely cost perspective, but that does have architectural approaches. Do you factor things like that in when you move up the stack?David: Absolutely. And really understanding on a Tidal inventory basis, understanding what the intent is of each of those workloads really does help you, from a cloud economics basics, to work out how much is reasonable in terms of cloud costs. So, for example, in Tidal, if you're doing app assessment, you're capturing any revenue to business that it generates, any staff productivity that it creates. And so, you've got the income side of that application workload. When you map that to on-premises costs and then later to cloud costs, your FinOps job becomes a lot easier because now you have the business context of those workloads too.Corey: So, one of the things that I have found is that you can judge the actual success of a project by how many people who work at the company claimed credit for it on LinkedIn, whereas conversely, when things don't work out super well, it's sort of a crickets moment. I'm curious as to your perspective on whether there is such a thing as a migration failure, or is it simply a, “Oh, we're going to iterate on this in a new direction. We've replaced a failing part, which turned out, from our perspective, to be our CIO, but we have a new one who's going to move us into cloud in the proper time and space.” We go through more of those things than some people do underwear. My God. But is there such a thing as a failed cloud migration?David: There absolutely is. And I get your point that success has many fathers. You know, when clients have brought us in for that success party at the end, you don't recognize everybody there. But you know, failure can be, you know, you've missed on time, scope, or budget, and by those measures, I think 76% of IT projects were failing in 2018, when we ran those numbers.So absolutely, by those metrics, there are failed cloud migrations. What tends to happen is people claim success on the workloads that did migrate. They may then kick it out into a new project scope, the organizational change bit. So, we've had many customers who viewed the cloud migration as a lift-and-shift exercise and failed to execute on the organizational change and then months later realized, oh, that is important in order for my day two operations to really hum, and so then have embarked on that under a separate initiative. So, there's certainly a lot of rescoping that goes on with these things.And what we like to make sure we're teaching people—and we do this for free—is those lessons learned and pitfalls with cloud early on because we don't want to see all those headlines of failed projects under that; we want to make sure that customers are armed with here are the things you should consider to execute on as you go to cloud.Corey: Do you ever run an analysis on a workload when a customer is asking, “So, how should we go about migrating this?” And your answer is, “You should absolutely not?”David: Well, all applications can go to cloud, it's just a matter of how much elbow grease you want to put into it. And so, the absolutely not call comes from when that app doesn't provide any utility to the business or maybe it has a useful life of six more months and the data center is going to be alive for seven. So, that's when those types of judgment calls come in. Other times we've seen, you know, there's already a replacement initiative underway by the business. IT wasn't aware of it, but through our process and methodology, they engaged with the business for the first time and learned about it. And so, that helps them to avoid needing to migrate workloads because the business is already moving to Salesforce, for example.Corey: I imagine you're also relatively used to the sinking realization that customers often have when they're used to data center thinking and you ask them a question, like, “How many gigabytes a month does your application server send back and forth to your database server?” And their response, very reasonably, is, “Why on earth would I know the answer to that quest—oh, God. You mean, that's how it bills?” It's the sense of everything is different in cloud, sometimes, subtly, sometimes massively. But it's a different way of thinking.So, I guess my last real big question for you on this is, moving technology is relatively straightforward but migrating people is very challenging. How do you find that the people and the processes that have grown up in data center environments with people whose identities are inextricably linked the technology they work on, being faced with the idea of it is now time to pick up and move these things into an environment where things that were incredibly valuable guardrails in a data center environment no longer serve you well?David: Yeah. The people side of cloud migration is the more challenging part. It's actually one of the reasons we introduced a service offering around people change management. The general strategy is sort of the Kotter change process of creating that guiding coalition, the people who want to do something different, get them outside of IT, reporting out to the executives directly, so they're unencumbered by the traditional processes. And once they start to demonstrate some success of a new way of working, a new paradigm, you kind of sell that back into the organization in order to drive that change.It's getting a lot easier to position that organizational change aspects with customers. There's enough horror stories out there of people that did not take that approach. And quite rightly. I mean, it's tough to imagine, as a customer, like, if I'm applying my legacy processes to cloud migration, why would I expect to get anything but a legacy result? You know, and most of the customers that we talk to that are going to cloud want a transformational outcome, they want more business agility and greater staff productivity, and so they need to recognize that that doesn't come without change to people and change the organization. It doesn't mean you have to change the people out individually, but skilling the way we work, those types of things, are really important to invest in and I'd say even more so than the technology aspects of any cloud migration.Corey: David, I really want to thank you for taking the time to talk to me about something that is, I'd say near and dear to my heart, except I'm trying desperately not to deal with it more than I absolutely have to. If people want to learn more, where's the best place for them to find you?David: Sure. I mean, tidalcloud.com is our website. I'm also on Twitter @dcolebatch. I like to tweet there a little bit, increasingly these days. I'm not on Bluesky yet, though, so I won't see you there. And also on LinkedIn, of course.Corey: And we will, of course, put links to that in the [show notes 00:29:57]. Thank you so much for your time. I really appreciate it.David: Thanks, Corey. Great to be here.Corey: David Colebatch, CEO and founder of Tidal.cloud. I'm Cloud Economist Corey Quinn and this is Screaming in the Cloud. If you've enjoyed this podcast, please leave a five-star review on your podcast platform of choice, whereas if you've hated this podcast, please leave a five-star review on your podcast platform of choice, along with an angry comment that you will then struggle to migrate to a different podcast platform of your choice.Corey: If your AWS bill keeps rising and your blood pressure is doing the same, then you need The Duckbill Group. We help companies fix their AWS bill by making it smaller and less horrifying. The Duckbill Group works for you, not AWS. We tailor recommendations to your business and we get to the point. Visit duckbillgroup.com to get started.

Responsorial Psalm24:1bc-2, 3-4ab, 5-6R.    (see 6)  Lord, this is the people that longs to see your face.The LORD's are the earth and its fullness;    the world and those who dwell in it.For he founded it upon the seas    and established it upon the rivers.R.    Lord, this is the people that longs to see your face.Who can ascend the mountain of the LORD?    or who may stand in his holy place?One whose hands are sinless, whose heart is clean,    who desires not what is vain.R.    Lord, this is the people that longs to see your face.He shall receive a blessing from the LORD,    a reward from God his savior.Such is the race that seeks him,    that seeks the face of the God of Jacob.R.    Lord, this is the people that longs to see your face.

Subaru Outback 2.4 Turbo, the new XT model, is finally here after two long years. After what has got to be the longest gestation in Australian automotive history, the burning question is whether it's good enough. And is it any better than the old 3.6R? OLIGHT DISCOUNT! (These are awesome.) Get 12% off here >> Use code AEJC On Bullshit by Harry G Frankfurt >> F*#king Apostrophes textbook: https://amzn.to/3IpskpA Save thousands on any new car (Australia-only) by contacting me via AutoExpert.com.au here >> Help support my independent reporting, securely, via Patreon here >> AutoExpert discount roadside assistance package (with no joining fees) here >> Did you like this report? You can help support the channel, securely via PayPal here >>

Well, last week I got distracted by a certain dive watch by a certain brand (it was Tudor) and didn't get to my coverage of Geneva Watch Days 2022. So, this week, I highlight five releases from GWD that were of interest from brands ranging in style and price from Doxa to Frederique Constant to MB&F. Sit back and enjoy a little trip to Geneva.This week's sponsor is the Windup Watch Shop, which recently added the newest iterations of Seiko's Save the Ocean dive watches. Based on iconic divers from Seiko's archives, this trilogy has been updated with their newest 6R automatic movements, and gorgeous textured dials inspired by ice. Check them out and more and WindupWatchShop.comTo stay on top of all new episodes, you can subscribe to The Worn & Wound Podcast — now available on all major platforms including iTunes, Google Play, Stitcher, Soundcloud, Spotify, and more. You can also find our RSS feed here.And if you like what you hear, then don't forget to leave us a review on iTunes.If there's a question you want us to answer you can hit us up at info@wornandwound.com, and we'll put your question in the queue. 

Anisotropy and characteristic scales in halo density gradient profiles by X. Wang et al. on Thursday 08 September We use a large N-body simulation to study the characteristic scales in the density gradient profiles in and around halos with masses ranging from $10^{12}$ to $10^{15} h^{-1}{rm M_odot}$. We investigate the profiles separately along the major (T_1) and minor (T_3) axes of the local tidal tensor and how the characteristic scales depend on halo mass, formation time, and environment. We find two kinds of prominent characteristic features in the gradient profiles, a deep `valley' and a prominent `peak'. We use the Gaussian Process Regression to fit the gradient profiles and identify the local extrema to determine the scales associate with these features. Around the valley, we identify three types of distinct local minima, corresponding to caustics of particles orbiting around halos. The appearance and depth of the three caustics depend significantly on the direction defined by the local tidal field, formation time and environment of halos. The first caustic is located at a radius r>0.8R_{200}, corresponding to the splashback feature, and is dominated by particles at their first apocenter after infall. The second and third caustics, around 0.6R_{200} and 0.4R_{200} respectively, can be determined reliably only for old halos. The first caustic is always the most prominent feature along T_3, but may not be the case along T_1 or in azimuthally-averaged profiles, suggesting that caution must be taken when using averaged profiles to investigate the splashback radius. We find that the splashback feature is approximately isotropic when proper separations are made between the first and the other caustics. We also identify a peak feature located at $sim$ 2.5R_{200} in the density gradient profile. This feature is the most prominent along T_1 and is produced by mass accumulations from the structure outside halos. We also discuss the origins of these features and their observational implications. arXiv: http://arxiv.org/abs/http://arxiv.org/abs/2206.12163v2

CHECK US OUT ON YOUTUBE!SAVE $20 ON YOUR FIRST SEATGEEK ORDER WITH PROMO CODE: CHASEFOR28The Chatter: Hey Batter, BatterTrade Deadline ReviewAndrew Benintendi (OF)Scott Effross (RHP)Frankie Montas (RHP) - Sun, 8/7, 6R, 3 IPLou Trivino (RHP)Gallo to LAD for Clayton Beeter (RHP)Montgomery to STL for Harrison Bader (OF)Summer SlumpingCole Train Derailed?JudgeVPUp and In: Week In ReviewOverall Record: 70-39, 1st AL EastALE TOR 9.5, AL 0.5 HOU, MLB -5 LADRecord this week (Fri-Sun): 1-5SEA 1-2STL 0-3Currently Playing STLSwept by STLLow and Away - The Week Ahead8/8-10 @ SEA8/12-14 @ BOSYankee TriviaIn 1999, the Yankees and Red Sox finally played each other in the postseason for the first time, in the ALCS. Who was the MVP of that series?-----Support The Chase for 28 Podcast with Official MerchPurchase Yankee GearBecome a Chase for 28 Podcast Legend@chasefor28pod on Twitter - https://twitter.com/chasefor28podJoin the Chase for 28 on FacebookSupport this show http://supporter.acast.com/chasefor28. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

In this episode I am once again joined by Delson Armstrong, spiritual teacher, meditation virtuoso, and author of ‘A Mind Without Craving'. Delson draws on his scriptural knowledge and personal experience to take a deep dive into dependent origination, the doctrine believed by many Buddhists to be the key to enlightenment. In practical and relatable terms, Delson explains how this doctrine works, why it is important yet so often misunderstood, and how to use meditation to move from an intellectual understanding to the experiential understanding that is Buddhist enlightenment. Delson also compares the enlightened to the unenlightened experiences of time, memory, and decision making process, and gives a surprising answer to the question: can enlightened people make mistakes? …

 Video version: https://www.guruviking.com/podcast/155-key-to-enlightenment-delson-armstrong-3 
Also available on Youtube, iTunes, & Spotify – search ‘Guru Viking Podcast'. … Topics include: 00:00 - Intro 00:53 - How to obtain an experiential understanding 05:56 - Essence of Dependent Origination 07:37 - How choices create reality 11:09 - Delson explains the 12 links 21:38 - Common mistakes in understanding the 12 links 24:25 - 6R's as a craving intervention 30:09 - Consequences of disrupting the 12 links via meditation 36:30 - Does the wisdom mind generate karma? 39:01 - Exhaustion of past life karma 41:09 - Enlightened vs unenlightened experience of life 45:14 - Enlightened vs unenlightened experience of time, memory, and future planning 48:38 - Enlightened vs unenlightened decision making processes 55:22 - Why do enlightened people make mistakes? 01:00:03 - Lifting the veil that filters reality 01:06:36 - Trauma how to recondition the mind 01:15:01 - Letting go of craving is wholesome 01:17:21 - Is cultivation of wholesome states necessary? 01:20:39 - How purification works 01:23:42 - Healing trauma and MDMA-assisted therapy 01:27:39 - Simply observing suffering is not enough 01:31:24 - Riding the 12 links to stream entry and beyond 01:41:46 - Practical advice for the practitioner ... Previous episodes with Delson Armstrong: - https://www.guruviking.com/ep120-meditation-virtuoso-delson-armstrong/ - https://www.guruviking.com/ep127-siddha-tales-delson-armstrong-2/ - https://www.guruviking.com/podcast/ep136-meeting-of-the-dharmas-daniel-ingram-delson-armstrong To find out more about Delson Armstrong, visit: - https://www.suttavada.foundation/our-teachers/ - https://www.dhammasukha.org/ 
For more interviews, videos, and more visit: - www.guruviking.com Music ‘Deva Dasi' by Steve James

Here are 13 players I have as draft day steals, I'll also post a link to my Twitter message as well where I posted my full Top 100E23 9 Chennedy Carter 22P, 2R, 4A, 1TPM, 1S(2), 0B(0) = 31 High risk, high reward player. Made her projections based off stats of her playing in 25+ minutes the past 2 seasons. Only 27 career games, but the superstar potential is apparentE43 10 Alyssa Thomas 13.5, 8.5R, 4A, 0TPM, 2S(4), .5B(1) = 31- Missed almost all of last season, but I'm fully expecting a return to her dominate self. She averaged a career high in points (15.5), Rebounds (9.0), Assists (4.8) and Steals in 2020 (2.0)E34 14 ATL Rhyne Howard 16P, 6R, 2A, 2TPM, 1.5S(3), .5B(1) = 30- This ranking is compiled completely off potential obviously, with this being her rookie season. She should get a full opportunity to start however, and think we can expect similar numbers to her Freshman season at UK when she was getting acclimated to a higher skill level game and still stuffed the stat sheetE37 27 DAL Satou Sabally 13P, 7R, 2.5A, 1TPM, .5S(1), 1B(2) = 26.5- Another high risk, high reward pick. Similar amount of games played to Chennedy the past 2 seasons with only 33 combined games. Contributes in every category and a consistent threat if she can stay healthyE53 29 MIN Angel McCoughtry 15P, 5R, 2.5A, .5TPM, 1S(2), .5B(1) = 26- She's only been able to play 20+ games in 2/4 last seasons with 2 games combined in the other 2. If she's able to stay healthy though, even in limited minutes like she was for Vegas in 2020, she simply produced at 20 Minutes/Game 14.5 Points, 5 Rebounds, 2.5 Assists, and 1.3 StealsE47 31 LVG Dearica Hamby 12.5P, 7R, 2.5A, .5TPM, 1.5S(3), 0B(0) = 25.5 Doesn't dominate in any category, but consistently produces double digit point performances and has done it for 3 consecutive seasons.E67 42 LAS Amanda Zahui B 9P, 7R, 1.5A, 1.5TPM, 1S(2), 1B(2) = 23- Even with Liz Cambage in the Sparks lineup, AZB should still receive around 23-25 minutes a game where she's contributed in a lot of areas, including knocking down 3's and constantly contributing to the double stat categoriesE66 46 LAS Kristi Toliver 12P, 2R, 4.5A, 1.5TPM, 1S(2), 0B(0) = 22 Only got to play in 19 games last season and had her lowest minutes since 2011 and her lowest PPG since 2011. Before last year, she has 9 straight seasons of double digit points (out 2020) and 8 straight of 3+ assistsE72 49 ATL Aari McDonald 10P, 3R, 3.5A, 2TPM, 1.5S(3), 0B = 21.5 Another projection based off potential, but should get ample opportunity this season. If she averages 25+ a game she'll consistently get 20+ fantasy point games. I'll go into her a lot more in my Atlanta Dream player profiles next week, but look at her /40 minute statsE70 55 CHI Julie Allemand 8P, 4.0R, 5A, 1TPM, 1S(2), .5B(1) = 21 She only played one season with the Fever in 2020, but she can excel if given the minutes with the Sky. Great pickup for deeper drafts, I wouldn't recommend drafting her in generic roster level leagues with no guarantees on how much she'll play. In her lone season with the Fever in 2020 she averaged 8.5Pts, 4.5Reb, 5.8 Assists and 1.1 Stealshttps://twitter.com/enfpdreamfan/status/1515755957044846601?s=21&t=-zVPiGykvPguDSaOSoz6XQAs always thanks https://herhoopstats.com for easy to use expansive filters!!!

Volvemos a la carga una semana más con un programa en el cual hablamos de las pocas novedades que hay y hacemos un gran top de aliados de Agresividad contando además esta vez con un invitado (que pronto no lo será) y con vuestros votos. Noticias: 00:11:38 Cómic de la semana: 00:32:16 Civil War Top aliados agresividad: 00:37:34 10- Marvel Boy 5 ptos 9- Tigra 9 ptos 7-8 El vigia & Vigor 21 ptos 6- Avispa 29 ptos 5- Throg 33 ptos 4- Bicho 38 ptos 3- Angela 42 ptos 2- Thor 43 ptos 1- Hulk 47 ptos -Tigra: 1D, 1R, 1J, 2JC= 5 ptos 4P = 9 ptos -Hulk: 1JC, 7R, 9J, 10G, 10D = 37 ptos 10P= 47 pts -Marvel Boy: 1G, 4D, = 5 ptos -Avispa: 2J, 6D, 6R, 9G = 23 ptos 6P= 29 ptos -Spidergirl: 2R, 5G, 8JC, = 15 ptos 2P= 17ptos -Throg: 2D, 3G, 5J, 8R, 10JC = 28 ptos 5P= 33ptos -Hulka: 2G, 3J, 3D, = 8 ptos -El Vigia: 3JC, 8G, 10J = 21 ptos -Vigor: 3R, 4JC, 5D, 6G = 18 ptos 3P= 21ptos -Thor (Odinson): 4G, 7D, 7JC, 8J, 10R= 36 ptos 7P= 43ptos -Bicho: 4J, 5JC, 5R, 7G, 9D = 30 ptos 8P= 38ptos -Valkiria: 4R, 6JC, 6J,= 16 ptos 1P= 17 ptos -Angela: 7J, 8D, 9R, 9JC = 33 ptos 9= 42ptos Sección del oyente: 03:01:47 ¡Esperamos que os guste! Recuerda que puedes sugerirnos, preguntarnos, quejarte o insultarnos en: Telegram: t.me/lamanodethanos Whatsapp: https://bit.ly/mtWhtspp Twitter/Instagram: @LaManodeThanos E-mail: lamanodethanos@gmail.com Facebook: Comunidad MarvelChampions LCG España lamanodethanos.blogspot.com Además si quieres ayudarnos a crecer y mejorar: https://www.patreon.com/lamanodethanos

-La cadena de hamburguesas Wendy's anuncia planes de expansión en México -DHL Express incrementa su flotilla eléctrica con la incorporación de 50 vehículos renault master -Inaugura Solistica Almacén Multi cliente en Monterrey -GENOMMA LAB continúa progresando a nivel regional en su estrategia de sostenibilidad, a un año de su puesta en marcha -Los mexicanos incrementarán un 34% su consumo de alimentos en restaurantes: Kantar -Cargill y CIMMYT abren convocatoria al Premio a la Seguridad Alimentaria y Sustentabilidad, edición 2022 -Los mexicanos incrementarán un 34% su consumo de alimentos en restaurantes: Kantar -IBM se une a Logicalis para acelerar la adopción de 5G en empresas -EY presenta estrategias de migración a la Nube con el respaldo de las 6R. NOTICIAS INTERNACIONALES Spotify dice que suspenderá su servicio en Rusia ENTREVISTA con Sandra Santuario, Químico Fármaco Biólogo por la Facultad de Ciencias Químicas de la Universidad Juárez del Estado de Durango, ganadora mexicana de 25 Mujeres en la Ciencia Latinoamérica 2022. ENTREVISTA con Klaus German, presidente de la revista Ganar-Ganar sobre la Décima Noveda Edición de los Premios Ganar-Ganar. VIDEOCOLUMNA con Carol Ocampo, manager en healthcare & life science by PageGroup BAR EMPRENDE EN IDEAS DE NEGOCIOS Si queremos cambiar al mundo primero necesitamos cambiar nosotros, convertirnos en héroes cotidianos. Aquí te compartimos 9 ideas para volverte un agente de cambio. ¡Cierre de temporada de Bar Emprende! RESUMEN DE MERCADOS con Marisol Huerta, del Banco Ve por Más.

Big Mac Index is it tradeable $MCD $EURCHF @hfrfromthefloor challenges @ChefGruel to Shrimp bracket Housing in Sydney in Bear Market @LongTplexTrader escape while you can, O Canada next up $6R bouncing as Putin demands $CL_F payments in kind. Orwell 2022

Reading IJer 17:5-8Thus says the LORD:            Cursed is the one who trusts in human beings,                        who seeks his strength in flesh,                        whose heart turns away from the LORD.            He is like a barren bush in the desert                        that enjoys no change of season,            but stands in a lava waste,                        a salt and empty earth.            Blessed is the one who trusts in the LORD,                        whose hope is the LORD.            He is like a tree planted beside the waters                        that stretches out its roots to the stream:            it fears not the heat when it comes;                        its leaves stay green;            in the year of drought it shows no distress,                        but still bears fruit.Responsorial PsalmPs 1:1-2, 3, 4 and 6R (40:5a) Blessed are they who hope in the Lord.Blessed the man who follows not            the counsel of the wicked,nor walks in the way of sinners,            nor sits in the company of the insolent,but delights in the law of the LORD            and meditates on his law day and night.R Blessed are they who hope in the Lord.He is like a tree            planted near running water,that yields its fruit in due season,            and whose leaves never fade.Whatever he does, prospers.R Blessed are they who hope in the Lord.Not so the wicked, not so;            they are like chaff which the wind drives away.For the LORD watches over the way of the just,            but the way of the wicked vanishes.R Blessed are they who hope in the Lord.GospelLk 6:17, 20-26Jesus came down with the Twelveand stood on a stretch of level groundwith a great crowd of his disciplesand a large number of the peoplefrom all Judea and Jerusalemand the coastal region of Tyre and Sidon.And raising his eyes toward his disciples he said:            “Blessed are you who are poor,                        for the kingdom of God is yours.            Blessed are you who are now hungry,                        for you will be satisfied.            Blessed are you who are now weeping,                        for you will laugh.            Blessed are you when people hate you,                        and when they exclude and insult you,                        and denounce your name as evil                        on account of the Son of Man.Rejoice and leap for joy on that day!Behold, your reward will be great in heaven.For their ancestors treated the prophets in the same way.            But woe to you who are rich,                        for you have received your consolation.            Woe to you who are filled now,                        for you will be hungry.            Woe to you who laugh now,                        for you will grieve and weep.            Woe to you when all speak well of you,                        for their ancestors treated the false prophets in this way.”

Hello and welcome to yet another exciting edition of The HourTime Show, the official podcast of WristWatchReview.com. Your hosts this week are Victor (@vmarks on Twitter), Nicholas (@nicholasadeleon), and Patrick (@PatrickWatches). For new listeners, Patrick is the managing editor of WristWatchReview but his schedule typically doesn't allow him to record with us very easily. But we're happy to have him on the pod this week, especially as John was busy with work stuff. Anyway! We've got a big and juicy news-filled podcast this week. After some initial banter about watch size preferences, we dive into the just-announced King Seiko re-launch and an interesting interview the CEO of Tag Heuer gave to Hodinkee. With King Seiko, we discuss our initial reaction to the new watches (mixed, though Nicholas is largely a fan) and what we would have done differently. One major complaint people seem to have is the use of the 6R movement, in a $1700 watch. This movement has somewhat of a mixed reputation online (it doesn't appear to keep time very well, for one), and to see it in a watch at this price point is... well, people aren't happy. With Tag, we mainly discuss where the brand "fits" in the watch world today, and how we might market a watch brand specifically to a younger demo. That's about the gist of this week. Thanks once again to Andrew Haworth for producing this week's episode. Keep it locked to WristWatchReview.com and @wristwatchreview on Instagram for more fun watch content. As always, you can reach us by email at tips@wristwatchreview.com, DM us on Instagram, or reach out to us on Twitter. Thank you for listening, and have a great week! --- Support this podcast: https://anchor.fm/the-hourtime-show/support

John Deere introduceert nieuwe 6R-serie, Bobcat bedient laders op afstand en Chinezen komen met robotmaaidorser. Dit en meer in het Mechaman Maandoverzicht van november 2021.

First Reading:Is 30:19-21, 23-26Thus says the Lord GOD,    the Holy One of Israel:O people of Zion, who dwell in Jerusalem,    no more will you weep;He will be gracious to you when you cry out,    as soon as he hears he will answer you.The Lord will give you the bread you need    and the water for which you thirst.No longer will your Teacher hide himself,    but with your own eyes you shall see your Teacher,While from behind, a voice shall sound in your ears:    “This is the way; walk in it,”    when you would turn to the right or to the left.He will give rain for the seed    that you sow in the ground,And the wheat that the soil produces    will be rich and abundant.On that day your flock will be given pasture    and the lamb will graze in spacious meadows;The oxen and the asses that till the ground    will eat silage tossed to them    with shovel and pitchfork.Upon every high mountain and lofty hill    there will be streams of running water.On the day of the great slaughter,    when the towers fall,The light of the moon will be like that of the sun    and the light of the sun will be seven times greater    like the light of seven days.On the day the LORD binds up the wounds of his people,    he will heal the bruises left by his blows.Responsorial Psalm147:1-2, 3-4, 5-6R.    (see Isaiah 30:18d)  Blessed are all who wait for the Lord.Praise the LORD, for he is good;    sing praise to our God, for he is gracious;    it is fitting to praise him.The LORD rebuilds Jerusalem;    the dispersed of Israel he gathers. R.    Blessed are all who wait for the Lord.He heals the brokenhearted    and binds up their wounds.He tells the number of the stars;    he calls each by name.R.    Blessed are all who wait for the Lord.Great is our LORD and mighty in power:    to his wisdom there is no limit.The LORD sustains the lowly;    the wicked he casts to the ground.R.    Blessed are all who wait for the Lord.AlleluiaIs 33:22R. Alleluia, alleluia. The LORD is our Judge, our Lawgiver, our King;he it is who will save us.R. Alleluia, alleluia.GospelMt 9:35–10:1, 5a, 6-8Jesus went around to all the towns and villages,teaching in their synagogues,proclaiming the Gospel of the Kingdom,and curing every disease and illness. At the sight of the crowds, his heart was moved with pity for thembecause they were troubled and abandoned,like sheep without a shepherd.Then he said to his disciples,“The harvest is abundant but the laborers are few;so ask the master of the harvestto send out laborers for his harvest.” Then he summoned his Twelve disciplesand gave them authority over unclean spirits to drive them outand to cure every disease and every illness. Jesus sent out these Twelve after instructing them thus,“Go to the lost sheep of the house of Israel. As you go, make this proclamation: ‘The Kingdom of heaven is at hand.' Cure the sick, raise the dead,cleanse lepers, drive out demons.Without cost you have received; without cost you are to give.”

Vítejte u dalšího dílu podcastu Rodičovská posilovna. Psychoterapeut Honza Vávra psycholožkou Ivanou Štefkovou si povídají v edici Nad věcí o tom, co posiluje odolnost dětí. Vztáhují to aktuálně k tradici Mikuláše a čertů. Mluví o tom, kdy nás zážitky, které mohou vyvolávat strach posílují a otužují, kdy zůstávají hrou, a kdy mohou být naopak až traumatizující. Tentokrát nad koncepty 7C odolnosti podle Dr. Ginsburga a principů 6R podle Dr. Bruce Perryho, které dokáží uzdravovat traumatické zážitky. Zmíněné knihy: Building Resilience in Children and Teens - Kenneth R. Ginsburg What Happened to You?: Conversations on Trauma, Resilience, and Healing - Oprah Winfrey, Bruce D. Perry

Richting, Ruimte, Resultaten, Rekenschap, Relatie en Reflectie.Met Carlo Post, gemeentesecretaris van de gemeente Dordrecht heb ik een zeer inspirerend en explorerend gesprek over het 6R leiderschapsmodel.Hoe hangen deze R-en met elkaar samen? Waarom kun je al aan de slag als het voor 80% goed is? En wat hebben de duiven op de Dam te maken met Johan Cruijff en pokeren?Heb je tips? Of wil je meer weten?Christianvdberg@gmail.comof https://www.linkedin.com/in/christianvandenberg/

El año 2020 nos enseño que debemos ser flexibles en nuestra estrategia de mercadeo. El canal digital posee muchas ventajas pero debe ser considerado dentro de una estrategia integral de mercadeo y ventas. En este episodio hablaremos con Javier Medrano sobre cuáles son los factores de éxito al momento de implementar una campaña de mercadeo integral. Hablaremos de las 6R del mercadeo, que ahora las han extendido a 10 R, así como las nuevas tendencias en mercadeo para lograr cumplir la meta de toda empresa que es sobrevivir y prosperar. Esperamos que les sea de valor.

Do you or someone you know struggle with depression? Has the pandemic been rough on your mental health? Want to know what foods and supplements can help combat low mood? Tune in to hear Ali and Becki discuss the multifactorial causes of depression and how immune dysfunction and mood disturbance can often overlap.    In this episode, Ali and Becki discuss the 6R approach from The Anti-Anxiety Diet and how these principles can apply beyond anxiety to depression and other mood disorders. Learn about the pathogen-host theory of depression, why the gut truly is the second brain of the body and how you can use food as medicine to support mood. Plus get supplement, lab, and lifestyle recommendations.   Also in this episode:  Food As Medicine Ketosis Program - New Spots Just Opened, Join Today! The Anti-Anxiety Diet  The Anti-Anxiety Diet Cookbook GAPS Diet - Natasha McBride Impact of Pandemic & Lockdowns on Depression The Pathogen-Host Theory of Depression The Depression Immune Connection Supplement Support for DepressionHow to Do a Probiotic Challenge Anti-Inflammatory Bundle: Super Turmeric, EPA-DHA Extra, Cellular Antiox Digestive Essentials: Baseline probiotic, Digestaid, GI Lining Support Adrenal Rebound Bundle: Bio-C Plus, Adrenal Support, Adaptogen Boost Micronutrients and MoodZinc IronMultidefense with Iron Vitamin DVitamin D Balanced Blend Vitamin CBio-C Plus The Protein Neurotransmitter ConnectionGrassfed Whey The Adrenal Depression ConnectionAdrenal Rehab Program Lifestyle Support Dr. Deb Kern  Labs for DepressionNeurohormone Lab Micronutrient Panel   Sponsors for this episode: This episode is sponsored by FOND Bone Broth Tonics, Your Sous Chef in a Jar. FOND is slow simmered and lovingly tended from simmer to seal. They partner with organic farms and hand-pick and pair ingredients to optimize absorption and taste. Use code ALIMILLERRD to save at fondbonebroth.com.

New Subaru Outback - on-sale (finally) this March, after delays of what seems like geologic time. But Subaru has a major problem, and we really need to talk about this, in the interest of integrity. Save thousands on any new car (Australia-only): https://autoexpert.com.au/contact AutoExpert discount roadside assistance package: https://247roadservices.com.au/autoexpert/ Did you like this report? You can help support the channel, securely via PayPal: https://www.paypal.com/cgi-bin/webscr?cmd=_s-xclick&hosted_button_id=DSL9A3MWEMNBW&source=url Subaru Australia is stuck in a rut of extreme boredom. Product planning mediocrity. And they need to snap right out of it. Because cars are allowed to be exciting - in fact, it’s better if they are. Better from some of us. Certainly better for Subaru, overall. Don’t get me wrong - huge Subaru fan. I’ve owned four new Subarus: two WRXs, an Outback and a Forester XT. And that XT was my favourite - WRX in sheep’s clothing. Could’ve used more grip, but hey - it was fun. Subaru gets full marks from me for looking after its customers. If you’ve got a problem, you get the benefit of the doubt from Subaru. (Unlike Volkswagen, Mercedes, Nissan, Jeep, etc., the default setting of which is to throw you under the bus in the same situation.) So I’m coming at this like something of a disappointed fan. Last week, Subaru Shitsville issued a press release concerning the new Outback. Finally here in three months, they claim. The bombshell for us here in Shitsville is: 2.5i boxer four atmo petrol engine only. Right across the range. No 3.6R, no diesel, and even more disappointingly, no new 2.4-litre turbo boxer four. You know, the one developed specifically for this vehicle, which suits it so perfectly, and tops the range in Retardistan. Developed as the logical successor to the 3.6R. "On the outside, the rugged exterior styling reinforces the Outback’s SUV capabilities, and every variant will be powered by a refined 2.5-litre horizontally opposed Boxer engine." - Subaru Shitsville Not good enough, dudes - just … not good enough. Try harder. Make stronger representations to the factory. It’s disgraceful - a company like Subaru should not aspire to mediocrity, in my view, and that’s exactly where this train wreck is heading. It’s almost as if Toyota’s stake in Subaru is metastasising through the business, at the highest level, philosophically. “Outback continues to set the standard for safety and driveability with an advanced suite of safety and driver assist technologies. Outback will have an incredible specification list cementing it as the flagship of the Subaru range.” - Blair Read there - Subaru’s dude at the top of the local import operation. Dude, if the first words which fall out of your pie-hole on new Outback, which one can only presume are the features you are the most tumescent about … if this rhetoric orbits ‘driver assist technologies’ - narcolepsy is imminent. Get a halo model at the top of the range - just get one, so that people who actually like cars and driving have something to aspire to, and/or gush over. Spend more cash on. Whatever.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.03.280834v1?rss=1 Authors: Herzog, D. P., Perumal, N., Manicam, C., Treccani, G., Nadig, J., Rossmanith, M., Engelmann, J., Jene, T., Hasch, A., van der Kooij, M. A., Lieb, K., Gassen, N. C., Grus, F. H., Mueller, M. B. Abstract: The delayed onset of antidepressant action is a major shortcoming in depression treatment. Ketamine, an N-methyl-D-aspartate (NMDA)-receptor antagonist and, more recently, its metabolite (2R,6R)-hydroxynorketamine (HNK) have emerged as promising rapid-acting antidepressants. Still, knowledge about their mechanism of action remains fragmentary. In the present study, we first confirmed the antidepressant-responsive mouse strain DBA/2J to be a suitable strain sensitive to the effects of both ketamine and HNK. To decode the molecular pathways mediating HNKs rapid antidepressant effects, we took advantage of an in vivo approach enabling longitudinal proteome profiling of acute and sustained antidepressant-like effects of (2R,6R)-hydroxynorketamine (HNK) in cerebrospinal fluid (CSF) of conscious DBA/2J mice. Serial CSF samples were investigated using an unbiased, hypothesis-free mass spectrometry-based approach. We identified a total of 387 proteins in murine CSF, among them were several protein targets involved in the glucocorticoid receptor signaling pathway; thus revealing an intriguing mechanistic link between HNKs antidepressant mechanism of action and regulation of the stress hormone system. In addition, mTOR and BDNF were predicted to be important upstream regulators of HNK treatment. Our data substantially contribute to a more precise understanding of the temporal dynamics and molecular targets underlying HNKs rapid antidepressant-like effects, and can be used as a proteomic database supporting the development of improved treatment strategies for depression in the future. Copy rights belong to original authors. Visit the link for more info

Show Notes Behind The Facade is a podcast dedicated to exploring the mental game and essential mindset critical to success in property investment & development. Hosted by veteran real estate entrepreneur Gavin J Gallagher, whose own career spans 25 years across a full spectrum of international assets and projects, this podcast aims to impart valuable insights and actionable strategies for building wealth in a structured and sustainable manner. Delivered through a combination of guest interviews and Gavin's own uniquely authentic and personal war stories of both his successes and failures, each week the show will cover a topics through the lens of innovation, inspiration or impact. In this weeks episode Gavin did a live Q&A and take you back to the very start of his career, talking about his first property purchase and his first land development deal. He then jumps forward a couple of years to 2005 when he had his best year as a property investor and talks about his 2 most profitable deals of that year. Finally to ensure balance and full transparency he ends the podcast by jumping forward to 2010 when he experienced his worst 2 deals that cost him and his partners a lot of money. During the episode Gavin also cover his 3E's and 6R's of investing. If you would like to participate in future live Q&A sessions please join the Facebook Group - Behind The Facade Community. Gavin posts daily live videos in the Facebook Group answering questions, providing insights and advice or just letting you tag along as he goes through his day at work. We also have a Behind The Facade Facebook Page where you can find a link to each episode and comment directly on it. Subscribe to the podcast so you don't miss an episode and connect with Gavin on social media (FB Page, LinkedIn, Twitter, Instagram). You can learn more by visiting Gavin's website www.gavinjgallagher.com and please subscribe to his YouTube channel PropTechTV. --- Send in a voice message: https://anchor.fm/gavinjgallagher/message

- 진행 : 서형욱 - 출연 : 한준, 유지선 워밍엄 | 크잘알 (정정용호 3연승 / 수원FC 정재용 / 장슬기와 함께 돌아온 WK리그) 전반전 | K리그1 6R 집중 리뷰 (식스 앤 더 시티, 그리고..) 후반전 | ㅋㅋㅋ 핫이슈 (슈퍼부인1 FC서울 왜이러나 / 슈퍼부인2 수원은 또 왜 이러나 / 재활공장 공장장 김병수)

If you’re anything like me, you look for any opportunity to go on a cruise. So when choosing to get away from it all with your brother, a cruise vacation sounds like a great idea. This week’s Cruise Story is about how Joe started a cruise tradition of vacationing with his brother.Share with me your thoughts, questions and comments via...Twitter: @therclblogFacebook: /royalcaribbeanblogPeriscope: @therclblogEmail: matt@royalcaribbeanblog.comLeave a voicemail: (408) 6R

In our recent conversation, Brian Lee shared an equity curve simulator tool, and that was a complete game-changer for me.   In the simulator, you enter your win percentage, your risk/reward ratio and a time period, and you really get to see your projected results over time.   When you are trading, when you are “in the moment”, you only see each individual trade, each loss, and each win. In one day you may lose 6 trades and you may only win 2 trades, leaving you with a pretty bad win/loss ratio. But as long as you stick to the 3:1 rule, all you lose is 6R. At the same time, by winning twice you get the same 6R, so you are actually OK at the end. However, you only get to see it this way if you’re looking at the big picture, as you do in the equity curve simulator. In the moment, 6 losses in a row might seriously hurt your confidence and destroy your mindset.   The lesson here is to pay less attention to the win percentage and each loss individually. Instead, focus more on following your profit plan long-term. I’m planning to give my 3:1 Reward to Risk trading strategy at least 3 months to let my wins and losses accumulate before drawing any conclusions.   Subscribe to my newsletter to see my trading tips and follow me on social media to see the latest updates.

On November 15, 2019, I broke two important trading rules that I’ve set up for myself. In hindsight, I should have known better. But this is the frustrating thing about trading: you can do so well for a few months and then just have a bad week and a nasty lapse. But let me tell you what happened. I have 2 important rules when trading: Never trade a stock that’s rotating its float Don’t jump back in on the same stock once I’ve been wrong  Whenever I break them, I pay for it. This time I took a 6R loss, which is huge for me since I usually try to keep it down to 1R.  This is what happens when I trade for the money rather than for the process. I took a large loss that took two recent wins out (I follow a 3:1 profit/loss ratio strategy). In retrospect, I did it out of frustration. I’ve been working on my trading game for solid 2 years, and it’s frustrating to still experience these lapses and struggles. The worst part is to have several great months in a row only to have this happen again.  AIHS, I don’t think I’ll ever forget you! Watch the full video to see what exactly I did wrong when stock trading and learn with me from my trading mistake.

Last episode I caught up with Leonie McCarthy retail project delivery specialist and owner of 6R.We talked about the retail online industry, the need to translate technology to make sense of the complexity, building teams and everyday there are lessons.Today I want to unpack our conversation about customer (or user) experience.What triggers a bad experience and what you promote as good experience.JC Three TipsUnderstand different customer personasPut yourself in your customers shoesAsk your customer for feedbackQuote from my conversation with Leonie ‘think about the success criteria, what does it look like, how do we explain it to our customer’.

In this episode, I catch up with Leonie McCarthy Owner of 6R working with retailers on ERP (enterprise resource planning), PLM (product lifecycle management) and e-commerce projects focusing on setting up internal structures and skills so both the retailer and vendor get good results.Leonie has worn many hats from subject matter expert, business analyst and project manager. She loves building great teams, leading people through change and contributing to practical solutions that get to the heart of solving problems.More recently 6R have been working closely with Accent Group digital team to deliver a whole ecosystem from new websites, integration with ERP and logistics including warehousing.We talk about:Working with your client and being the technology translator;The challenges facing the retail industry; andMaking our customer experience simple.You will find more about Leonie and what she does on her website https://www.6r.com.au/

Come prendere appunti: metodo per come prendere appunti efficacementeLibro Motivazione allo studio: https://amzn.to/2I9J8Fv-------------------------------------------------Come prendere appunti in classe velocemente? Come prendere appunti durante un evento?Ti piacerebbe sapere come studiare bene e velocemente?A chi non piacerebbe. Il punto è avere un metodo che possa rendere il tuo studio più semplice.Una prima cosa che ho imparato dalle mie esperienze, prima come studente e poi come ospite di eventi o conferenze, è che ognuno deve conoscere un metodo e poi adattarlo alle proprie esigenze.Prende appunti è utile per rafforzare i concetti ascoltati e ci sono diversi modi per farlo, nel video ti farò vedere quello che ho utilizzato e utilizzo ancora.Però prima di farlo, lo metterò a confronto con altri metodi, partendo dai 4 principi fondamentali per prendere appunti.https://youtu.be/8BvOo89R49ELINK E APPROFONDIMENTI:Libro sul Metodo di Studiohttps://amzn.to/2I9J8FvLa stenografiahttps://it.wikipedia.org/wiki/StenografiaMetodo Teelinehttps://en.wikipedia.org/wiki/Teeline_ShorthandWalter Pauk della Cornell University (ideatore metodo Cornell)https://en.wikipedia.org/wiki/Walter_PaukALTRI VIDEO SU FACEBOOKhttp://www.facebook.com/giuseppefrancopaginaCANALE PUBLIC SPEAKING PER IL BUSINESShttp://bit.ly/speaking4SSCRIVIMIinfo @ motivazionepersonale.comhttp://telegram.me/giuseppefrancoCome prendere appunti in classeSe vuoi imparare come prendere appunti ordinati, il metodo Cornell (o metodo delle 6R) è una delle soluzioni più semplici ed efficaciCome prendere appunti alle superioriCome Prendere Appunti Alle Medie mp3 totalmente gratis come prendere appunti università video HD Youtube HD

  Have you read The Anti-Anxiety Diet but are having a hard time getting started? Not sure what to eat once you’ve removed all of the inflammatory foods discussed in the book? Want strategy for successful implementation of the diet and recipe ideas for making it sustainable? Tune in to hear Ali and Becki discuss the 6R approach to The Anti-Anxiety Diet and go deep into each inflammatory food that is removed from the diet. Learn why ketosis is so therapeutic for anxiety and how you can sub out these foods in a way that focuses on abundance and therapeutic food goals!   In this Episode, Ali and Becki break down the reasons for removing gluten, soy, corn, sugar and dairy in The Anti-Anxiety Diet from their inflammatory impact to the influence of GMOs to hidden sources of these foods you need to be mindful of. Learn about therapeutic foods you can include in the diet to replace these inflammatory foods and connect the HOW and WHY of removal to aid in your success. Plus get a sneak peek of The Anti-Anxiety Diet Cookbook!   Also in This Episode: The Anti-Anxiety Diet Book - Grab Yours Here! Already Read It? Leave a Review on Amazon Here Episode 87 : The Gut Brain Axis What is The Anti-Anxiety Diet? Removing Inflammatory FoodsGlutenEpisode 74 : Are You Still Eating Gluten? SoyCoconut Aminos Packets Watch out for Soy Lecithin! Theo’s Chocolate Hu Kitchen Chocolate CornEPA DHA Extra Episode 117 : Real Food Keto and Natural Sweeteners SugarEpisode 89 : Why I Hate Non-Caloric Sweeteners DairyEpisode 82 : Pros and Cons of Dairy Supplements for Reducing Inflammatory Impact of FoodsDigestaid 3-5/day with food GI Lining Support 1 scoop at bed, 1 additional when exposed to inflammatory foods Ali Miller RD Amazon Store - Tons of Pantry Staples and Snacks Free of Inflammatory Items! Sneak Peek of The Anti-Anxiety Diet Cookbook! Upcoming Events Keto San Antonio Book Signing March 14   This episode is sponsored by Further Food, a female owned and operated company that provides the highest quality food as medicine supplements including their Collagen Peptides, Pasture-Raised Gelatin Daily Turmeric Tonic and Mindful Matcha.

If you haven’t heard about the 6-R Migration Patterns, then you probably haven’t heard about the 7-R. The 7th stands for R(e-Fit).In this podcast we chat with Mandus Momberg (@MandusMomberg), Principal Solution Architect at AWS. Mandus is sharing what he has learned from small to large scale application migration & modernization projects. We learn about Modernization Factories, that it is key to have decision maker buy-in and that the most common migration scenario is R(e-Fit).Our biggest takeaway are the 3 key measures of success after a migration: Availability, Elasticity & Agility! Now listen in …https://www.linkedin.com/in/mandusm/https://aws.amazon.com/migration-acceleration-program/

If you haven’t heard about the 6-R Migration Patterns, then you probably haven’t heard about the 7-R. The 7th stands for R(e-Fit).In this podcast we chat with Mandus Momberg (@MandusMomberg), Principal Solution Architect at AWS. Mandus is sharing what he has learned from small to large scale application migration & modernization projects. We learn about Modernization Factories, that it is key to have decision maker buy-in and that the most common migration scenario is R(e-Fit).Our biggest takeaway are the 3 key measures of success after a migration: Availability, Elasticity & Agility! Now listen in …https://www.linkedin.com/in/mandusm/https://aws.amazon.com/migration-acceleration-program/

From Wikipedia: Runways are named by a number between 01 and 36, which is generally the magnetic azimuth of the runway's heading in decadegrees. This heading differs from true north by the local magnetic declination. A runway numbered 09 points east (90°), runway 18 is south (180°), runway 27 points west (270°) and runway 36 points to the north (360° rather than 0°). When taking off from or landing on runway 09, a plane would be heading 90° (east). A runway can normally be used in both directions, and is named for each direction separately: e.g., "runway 33" in one direction is "runway 15" when used in the other. The two numbers usually differ by 18 (= 180°). If there is more than one runway pointing in the same direction (parallel runways), each runway is identified by appending Left (L), Center (C) and Right (R) to the number to identify its position (when facing its direction) — for example, Runways One Five Left (15L), One Five Center (15C), and One Five Right (15R). Runway Zero Three Left (03L) becomes Runway Two One Right (21R) when used in the opposite direction (derived from adding 18 to the original number for the 180° difference when approaching from the opposite direction). In some countries, if parallel runways are too close to each other, regulations mandate that only one runway may be used at a time under certain conditions (usually adverse weather). At large airports with four or more parallel runways (for example, at Los Angeles, Detroit Metropolitan Wayne County, Hartsfield-Jackson Atlanta, Denver, Dallas-Fort Worth and Orlando) some runway identifiers are shifted by 10 degrees to avoid the ambiguity that would result with more than three parallel runways. For example, in Los Angeles, this system results in runways 6L, 6R, 7L, and 7R, even though all four runways are actually parallel at approximately 69 degrees. At Dallas/Fort Worth International Airport, there are five parallel runways, named 17L, 17C, 17R, 18L, and 18R, all oriented at a heading of 175.4 degrees. Occasionally, an airport with only 3 parallel runways may use different runway identifiers, such as when a third parallel runway was opened at Phoenix Sky Harbor International Airportin 2000 to the south of existing 8R/26L — rather than confusingly becoming the "new" 8R/26L it was instead designated 7R/25L, with the former 8R/26L becoming 7L/25R and 8L/26R becoming 8/26. For clarity in radio communications, each digit in the runway name is pronounced individually: runway three six, runway one four, etc. (instead of "thirty-six" or "fourteen"). A leading zero, for example in "runway zero six" or "runway zero one left", is included for all ICAO and some U.S. military airports (such as Edwards Air Force Base). However, most U.S. civil aviation airports drop the leading zero as required by FAA regulation. This also includes some military airfields such as Cairns Army Airfield. This American anomaly may lead to inconsistencies in conversations between American pilots and controllers in other countries. It is very common in a country such as Canada for a controller to clear an incoming American aircraft to, for example, runway 04, and the pilot read back the clearance as runway 4. In flight simulation programs those of American origin might apply U.S. usage to airports around the world. For example, runway 05 at Halifax will appear on the program as the single digit 5 rather than 05 Runway designations change over time because the magnetic poles slowly drift on the Earth's surface and the magnetic bearing will change. Depending on the airport location and how much drift takes place, it may be necessary over time to change the runway designation. As runways are designated with headings rounded to the nearest 10 degrees, this will affect some runways more than others. For example, if the magnetic heading of a runway is 233 degrees, it would be designated Runway 23. If the magnetic heading changed downwards by 5 degrees to 228, the Runway would still be Runway 23. If on the other hand the original magnetic heading was 226 (Runway 23), and the heading decreased by only 2 degrees to 224, the runway should become Runway 22. Because the drift itself is quite slow, runway designation changes are uncommon, and not welcomed, as they require an accompanying change in aeronautical charts and descriptive documents. When runway designations do change, especially at major airports, it is often changed at night as taxiway signs need to be changed and the huge numbers at each end of the runway need to be repainted to the new runway designators. In July 2009 for example, London Stansted Airport in the United Kingdom changed its runway designations from 05/23 to 04/22 during the night. For fixed-wing aircraft it is advantageous to perform takeoffs and landings into the wind to reduce takeoff or landing roll and reduce the ground speed needed to attain flying speed. Larger airports usually have several runways in different directions, so that one can be selected that is most nearly aligned with the wind. Airports with one runway are often constructed to be aligned with the prevailing wind. Compiling a wind rose is in fact one of the preliminary steps taken in constructing airport runways. Note that wind direction is given as the direction the wind is coming from: a plane taking off from runway 09 would be facing east, directly into an "east wind" blowing from 090 degrees. Runway dimensions vary from as small as 245 m (804 ft) long and 8 m (26 ft) wide in smaller general aviation airports, to 5,500 m (18,045 ft) long and 80 m (262 ft) wide at large international airports built to accommodate the largest jets, to the huge 11,917 m × 274 m (39,098 ft × 899 ft) lake bed runway 17/35 at Edwards Air Force Base in California – developed as a landing site for the Space Shuttle. Takeoff and landing distances available are given using one of the following terms: TORA Takeoff Run Available – The length of runway declared available and suitable for the ground run of an airplane taking off. TODA Takeoff Distance Available – The length of the takeoff run available plus the length of the clearway, if clearway is provided. ASDA Accelerate-Stop Distance Available – The length of the takeoff run available plus the length of the stopway, if stopway is provided. LDA Landing Distance Available – The length of runway that is declared available and suitable for the ground run of an airplane landing. EMDA Emergency Distance Available – LDA (or TORA) plus a stopway. There exist standards for runway markings. The runway thresholds are markings across the runway that denote the beginning and end of the designated space for landing and takeoff under non-emergency conditions. The runway safety area is the cleared, smoothed and graded area around the paved runway. It is kept free from any obstacles that might impede flight or ground roll of aircraft. The runway is the surface from threshold to threshold, which typically features threshold markings, numbers, and centerlines, but not overrun areas at both ends. Blast pads, also known as overrun areas or stopways, are often constructed just before the start of a runway where jet blast produced by large planes during the takeoff roll could otherwise erode the ground and eventually damage the runway. Overrun areas are also constructed at the end of runways as emergency space to slowly stop planes that overrun the runway on a landing gone wrong, or to slowly stop a plane on a rejected takeoff or a takeoff gone wrong. Blast pads are often not as strong as the main paved surface of the runway and are marked with yellow chevrons. Planes are not allowed to taxi, take off or land on blast pads, except in an emergency. Displaced thresholds may be used for taxiing, takeoff, and landing rollout, but not for touchdown. A displaced threshold often exists because obstacles just before the runway, runway strength, or noise restrictions may make the beginning section of runway unsuitable for landings.It is marked with white paint arrows that lead up to the beginning of the landing portion of the runway.

The Ford 6R140 is impressive with its smooth shifts, durability, and dependability. In this episode, Paul and Chris talk to Morgan Primm of Midwest Diesel and Auto, a recommended expert on the 6R140. Morgan describes the 6R's typical problems but he also explains that even a completely failed transmission still works unlike its GM and Dodge counterparts. Primm describes upgrades and competition specs for the 6R. Special thanks to our sponsors: Wehrli Custom Fabrication WCFAB.com Exergy Performance Exergyperformance.com Alligator Performance alligatorperformance.com

We're in the studio today after an oddly tiring day, talking about some pretty important cars. In big news, Adi has bought a new daily driver and tells us about the adventures the team faced trying to acquire and register it. Zack was in the Nissan Qashqai, and Jerry was in the Jeep Wrangler Chief. Adi spent some time with the updated Subaru Legacy 3.6R, which somehow was his first time with a 3.6L Subaru. We briefly revisit the Corvette Grand Sport and talk about the end of our motorsports season with the Mazda MX-5 RF and Michelin Pilot Super Sport tires. 

ㅁ클래식 6R, 포커스 - 03분 08초 ㅁUCL 8강에는 어떤경기가? - 17분 04초 ㅁEPL 리버풀 챔스 희망 살리다 - 24분 14초 ㅁ목포 가야하는 이유는? - 30분 58초 - 진행 : 김유라 (데일리 풋볼리스트 취재기자) 패널 : 김환 (풋볼리스트 취재기자)

The Roads Untraveled podcast is back!! It's just Marcus, Jesse, and Grayson this week. We talk about our drive in the 2014 Subaru Legacy 3.6R as well as answer a listener question about the future of Mitsubishi. Make sure to Subscribe to the podcast on iTunes as well as our channel on Youtube.com/roadsuntraveledshow. Enjoy!

Rather than take a week off, Hooniverse host Jeff Glucker decided to knock out a 30 minute episode from the cozy confines of his own house. It's just Jeff this week as he prattles on about all sorts of random car goodness. Glucker recently drove the new Aston Martin V12 Vantage S Roadster as well as the Vanquish Volante, he then mixed it up and stepped up even further by spending a weekend with the Lamborghini Aventador Roadster.The chatter ranges from the aforementioned cars to the results of the Lightning Lap, some talk of the new Viper, and even a bit about the Subaru Legacy 3.6R. --- Support this podcast: https://anchor.fm/hooniverse/support

Rather than take a week off, Hooniverse host Jeff Glucker decided to knock out a 30 minute episode from the cozy confines of his own house. It's just Jeff this week as he prattles on about all sorts of random car goodness. Glucker recently drove the new Aston Martin V12 Vantage S Roadster as well as the Vanquish Volante, he then mixed it up and stepped up even further by spending a weekend with the Lamborghini Aventador Roadster.The chatter ranges from the aforementioned cars to the results of the Lightning Lap, some talk of the new Viper, and even a bit about the Subaru Legacy 3.6R.

Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling. While the T-helper 1 (Th1) cytokine interferon-gamma (IFN-γ) is well characterized as immune-modulatory and anti-fibrotic cytokine, the role of IFN-γ in lung endothelial cells (LEC) is less defined. Tumour necrosis factor alpha (TNF-α) is another mediator that drives vascular remodeling in inflammation by influencing CTGF expression. In the present study we investigated the influence of IFN-γ and TNF-α on CTGF expression in human LEC (HPMEC-ST1.6R) and the effect of CTGF knock down on human LEC. IFN-γ and TNF-α down-regulated CTGF in human LEC at the promoter-, transcriptional- and translational-level in a dose- and time-dependent manner. The inhibitory effect of IFN-γ on CTGF-expression could be almost completely compensated by the Jak inhibitor AG-490, showing the involvement of the Jak-Stat signaling pathway. Besides the inhibitory effect of IFN-γ and TNF-α alone on CTGF expression and LEC proliferation, these cytokines had an additive inhibitory effect on proliferation as well as on CTGF expression when administered together. To study the functional role of CTGF in LEC, endogenous CTGF expression was down-regulated by a lentiviral system. CTGF silencing in LEC by transduction of CTGF shRNA reduced cell proliferation, but did not influence the anti-proliferative effect of IFN-γ and TNF-α. In conclusion, our data demonstrated that CTGF was negatively regulated by IFN-γ in LEC in a Jak/Stat signaling pathway-dependent manner. In addition, an additive effect of IFN-γ and TNF-α on inhibition of CTGF expression and cell proliferation could be found. The inverse correlation between IFN-γ and CTGF expression in LEC could mean that screwing the Th2 response to a Th1 response with an additional IFN-γ production might be beneficial to avoid airway remodeling in asthma.