Podcasts about PM2

- Những tác động sức khoẻ do ô nhiễm không khí từ bụi PM2.5 và các khuyến nghị quản lý chất lượng không khí tại Hà Nội. - Kinh nghiệm quản lý chất lượng không khí tại một số quốc gia trên thế giới. --- Support this podcast: https://anchor.fm/vov1khcn/support

Dan is the co-founder and President of PM2, a services and consulting firm specializing in repair parts inventory for a broad array of business sectors. He lives in the Tampa Bay area with his wife, Julie, and their daughter, Laurel, who recently graduated from college. Dan is an avid fisherman, and he says the idea to launch PM2 was born on his boat back in 2001. Since then, God has brought Dan on an amazing and miraculous journey which included financial ruin, a death sentence, and the ultimate breaking of Dan's will. Through it all, God protected him, provided for him, and grew Dan's faith and obedience to become a better follower of Jesus. Today, Dan says he sees himself as a fisher of men, in training; a fisherman's apprentice as it were. In fact, he's just written a book called Fisherman's Apprentice – The Making Of A Fisher Of Men and it's already made number one best seller on Amazon. Fisherman's Apprentice is available on Amazon here: https://www.amazon.com/Fishermans-Apprentice-Making-Fisher-Men-ebook/dp/B08Z3BP5J2

ウイルス、細菌、花粉、PM2.5、様々な課題に果たして空気清浄機は有効なのか？仕組みからしっかり復習すれば製品選びの参考になるかも。※配信内容は個人の見解や感想です、実践する場合はご自身で再確認の上自己責任でお願いします。

Sunflower peptide as 'template' for potential analgesic Medical University of Vienna (Austria), June 28, 2021 A naturally occurring peptide in sunflower seeds was synthetically optimised and has now been identified as a potential drug for treating abdominal pain or inflammation (in the gastrointestinal tract, abdominal area and/or internal organs). That is the finding of an international study led by Christian Gruber from MedUni Vienna's Institute of Pharmacology (Center for Physiology and Pharmacology), which was conducted jointly with the University of Queensland and Flinders University in Australia and has now been published. The scientific aim of the study is to find analgesics that are only active in the periphery and do not cross the blood-brain barrier, as an alternative to commonly used synthetic opioids. Gruber explains the background: "Morphine was one of the first plant-based medicines and was isolated from the dried latex of poppies more than 200 years ago. It binds to opioid receptors in the brain and is still regarded as the main pillar of pain therapy. However, there is a high risk of opioid addiction, and an overdose - as a result of this strong dependency - inhibits the breathing centre in the brain, which can result in respiratory depression and, in the worst case, in death." For this reason, researchers throughout the world are trying to make analgesics safer and to find active drug molecules that do not have the typical opioid side-effects.  Sunflower extracts were to some extent used in traditional medicine for their anti-inflammatory and analgesic properties. In the current study, the scientists from Austria and Australia, primarily PhD student Edin Muratspahi?, isolated the plant molecule that may be responsible for this effect. Medicinal chemistry methods were then used to optimise the so-called sunflower trypsin inhibitor-1 (SFTI-1), one of the smallest naturally occurring cyclic peptides, by 'grafting' an endogenous opioid peptide into its scaffold.  A total of 19 peptides were chemically synthesized based on the original SFTI-1 blueprint and pharmacologically tested. "One of these variants turned out to be our lead candidate for as potential innovative analgesic molecule, especially for pain in the gastrointestinal tract or in the peripheral organs. This peptide is extremely stable, highly potent and its action is restricted to the body's periphery. Its use is therefore expected to produce fewer of the typical side-effects associated with opioids," point out Gruber and Muratspahi?.  The mode-of-action of the peptide is via the so-called kappa opioid receptor; this cellular protein is a drug target for pain relief, but is often associated with mood disorders and depression. The sunflower peptide does not act in the brain, hence there is much less risk of dependency or addiction. Furthermore, it selectively activates only the molecular signalling pathway that influences pain transmission but does not cause the typical opioid side-effects. The data of the animal model in the current study are very promising: the scientists see great potential for using this peptide in the future to develop a safe medication - which could be administered orally in tablet form - to treat pain in the gastrointestinal tract, and this drug could potentially also be used for related painful conditions, e.g. for inflammatory bowel disease.  Using Nature's blueprint The research of this MedUni Vienna laboratory led by Christian Gruber exploits the concept of using Nature's blueprint to develop optimised drugs. "We are searching through large databases containing genetic information of plants and animals, decoding new types of peptide molecules and studying their structure, with a view to testing them pharmacologically on enzymes or membrane receptors and ultimately utilizing them in the disease model," explains Gruber. Finally, potential drug candidates are chemically synthesised in a slightly modified form based on the natural blueprint, to obtain optimised pharmacological properties.   Study associates organic food intake in childhood with better cognitive development Analysis of multiple prenatal and childhood environmental risk factors suggests that poor nutrition, house crowding and indoor air pollution are associated with poorer cognitive function Barcelona Institute for Global Health (Spain), July 1, 2021 A study analysing the association between a wide variety of prenatal and childhood exposures and neuropsychological development in school-age children has found that organic food intake is associated with better scores on tests of fluid intelligence (ability to solve novel reasoning problems) and working memory (ability of the brain to retain new information while it is needed in the short term). The study, published in Environmental Pollution, was conceived and designed by researchers at the Barcelona Institute for Global Health (ISGlobal)--a centre supported by the "la Caixa" Foundation--and the Pere Virgili Health Research Institute (IISPV-CERCA).  The explanation for this association may be that "healthy diets, including organic diets, are richer than fast food diets in nutrients necessary for the brain, such as fatty acids, vitamins and antioxidants, which together may enhance cognitive function in childhood," commented lead author Jordi Júlvez, a researcher at IISPV-CERCA who works closely with ISGlobal.  The study also found that fast food intake, house crowding and environmental tobacco smoke during childhood were associated with lower fluid intelligence scores. In addition, exposure to fine particulate matter (PM2.5) indoors was associated with lower working memory scores.  The study, titled "Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries", used data on 1,298 children aged 6-11 years from six European country-specific birth cohorts (United Kingdom, France, Spain, Greece, Lithuania and Norway). The researchers looked at 87 environmental factors the children were exposed to in utero (air pollution, traffic, noise, various chemicals and lifestyle factors) and another 122 factors they were exposed to during childhood. A Pioneering Study The aim of the study was to analyse the influence of these exposures on the development and maturation of the human brain, since during childhood the brain is not yet fully developed for efficient defence against environmental chemicals and is particularly sensitive to toxicity, even at low levels that do not necessarily pose a risk to a healthy mature brain.  The originality of the study lies in its use of an exposome approach, i.e. the fact that it takes into account the totality of exposures rather than focusing on a single one. This approach aims to achieve a better understanding of the complexity of multiple environmental exposures and their simultaneous effect on children's neurodevelopment.  Another strength of the study, which analyses cohorts from six European countries, is its diversity, although this factor also poses the additional challenge of cultural differences, which can influence exposure levels and cognitive outcomes. Notable Associations The study found that the main determinants of fluid intelligence and working memory in children are organic diet, fast food diet, crowdedness of the family home, indoor air pollution and tobacco smoke. To date, there has been little research on the relationship between type of diet and cognitive function, but fast food intake has been associated with lower academic development success and some studies have also reported positive associations between organic diets and executive function scores. "In our study," explained Júlvez, "we found better scores in fluid intelligence and working memory with higher organic food intake and lower fast food intake."  In contrast, exposure to tobacco smoke and indoor PM2.5 during childhood may negatively affect cognitive function by enhancing pro-inflammatory reactions in the brain. Still, according to Júlvez, it is worth bearing in mind that "the number of people living together in a home is often an indicator of the family's economic status, and that contexts of poverty favour less healthy lifestyles, which in turn may affect children's cognitive test scores".  Some Surprising Findings  The study also found some unexpected associations, which could be explained by confounding and reverse causality. For example, a positive association was found between childhood exposure to perfluorooctane sulfonic acid (PFOS) and cognitive function, even though PFOS is considered an endocrine disruptor that may alter thyroid function and negatively influence cognitive development.  The study forms part of the large European project Human Early-Life Exposome (HELIX), as does another recent paper that used the same exposome and the same participants but looked at symptoms of attention deficit hyperactivity disorder (ADHD) and childhood behavioural problems. "We observed that several prenatal environmental pollutants (indoor air pollution and tobacco smoke) and lifestyle habits during childhood (diet, sleep and family social capital) were associated with behavioural problems in children," explained Martine Vrijheid, last author of the study and head of ISGlobal's Childhood and Environment programme. "One of the strengths of this study on cognition and the earlier study on behavioural problems is that we systematically analysed a much wider range of exposure biomarkers in blood and urine to determine the internal levels in the model and that we analysed both prenatal and childhood exposure variables," concluded Vrijheid.     Extract of mulberry leaves partially restores the composition of intestinal microbiota and strengthens liver glycogen fragility in diabetic rats Macau University of Science and Technology (China), June 28, 2021 According to news reporting out of Macau, People's Republic of China, research stated, “Mulberry leaf as a traditional Chinese medicine is able to treat obesity, diabetes, and dyslipidemia. It is well known that diabetes leads to intestinal microbiota dysbiosis.” Our news journalists obtained a quote from the research from the Macau University of Science and Technology, “It is also recently discovered that liver glycogen structure is impaired in diabetic animals. Since mulberry leaves are able to improve the diabetic conditions through reducing blood glucose level, it would be interesting to investigate whether they have any positive effects on intestinal microbiota and liver glycogen structure. In this study, we first determined the bioactive components of ethanol extract of mulberry leaves via high-performance liquid chromatography (HPLC) and liquid chromatography/mass spectrometry (LC/MS). Murine animal models were divided into three groups, normal Sprague-Dawley (SD) rats, high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic rats, and HFD/STZ-induced rats administered with ethanol extract of mulberry leaves (200 mg/kg/day). Composition of intestinal microbiota was analyzed via metagenomics by sequencing the V3-V4 region of 16S rDNAs. Liver glycogen structure was characterized through size exclusion chromatography (SEC). Both Student's t-test and Tukey's test were used for statistical analysis. A group of type 2 diabetic rat models were successfully established. Intestinal microbiota analysis showed that ethanol extract of mulberry leaves could partially change intestinal microbiota back to normal conditions. In addition, liver glycogen was restored from fragile state to stable state through administration of ethanol extract of mulberry leaves. This study confirms that the ethanol extract of mulberry leaves (MLE) ameliorates intestinal microbiota dysbiosis and strengthens liver glycogen fragility in diabetic rats.” According to the news editors, the research concluded: “These finding can be helpful in discovering the novel therapeutic targets with the help of further investigations.”     Supplemental antioxidants may reduce exacerbations in cystic fibrosis     University of Colorado, July 2, 2021 An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with cystic fibrosis(CF), according to new research published online iin the American Journal of Respiratory and Critical Care Medicine. In "Effects of an Antioxidant-Enriched Multivitamin in Cystic Fibrosis: Randomized, Controlled, Multicenter Trial," Scott D. Sagel, MD, PhD, a professor of pediatrics at Children's Hospital Colorado and director of the University of Colorado Cystic Fibrosis Center, and coauthors report a 50 percent reduced risk of time to the first exacerbation requiring antibiotics in those receiving the supplemental antioxidants. During the 16-week study of 73 patients (36 received supplemental antioxidants), 53 percent of the antioxidant-treated group experienced 28 exacerbations, compared to 68 percent of the control group who experienced 39 exacerbations. The researchers also found that supplemental antioxidants increased circulating antioxidant concentrations of beta-carotene, coenzyme Q10, gamma-tocopherol (a form of vitamin E) and lutein and transiently decreased inflammation (at 4 weeks, but not 16 weeks) as measured by two blood-based biomarkers of inflammation, calprotectin and myeloperoxidase (MPO). People with CF typically experience chronic bacterial infections, which lead to inflammation and the release of "vast amounts of reactive oxygen species in the airways," the authors wrote. Normally, they added, the body would marshal an antioxidant defense to neutralize this oxidant stress, but CF is characterized by dietary antioxidant deficiencies. This contributes to an oxidant-antioxidant imbalance and more inflammation, which leads to lung damage and a progressive loss of lung function. "Improving antioxidant status in CF is an important clinical goal and may have a positive effect on health," Dr. Sagel said. "Oral antioxidant formulations had been tested in CF with mixed results. However, there had not been a well-designed randomized controlled trial of an antioxidant 'cocktail' that included multiple antioxidants in a single formulation." This phase 2 trial, conducted at 15 CF centers affiliated with the CF Foundation Therapeutics Development Network, enrolled patients who were 10 years and older (average age 22 years), with pancreatic insufficiency, which causes malabsorption of antioxidants. Participants had an FEV1, the measure of how much air can be forcefully exhaled in one second, between 40 and 100 percent of what would be predicted, based on age, gender, height and a range of other characteristics. Patients in the control group received a multivitamin without antioxidant enrichment. The two groups tolerated their vitamins equally well, and there were no differences in adverse events between the two groups. The study did not meet its primary endpoint: change in sputum MPO concentration over 16 weeks. The authors chose sputum MPO "rather than another marker of airway inflammation such as neutrophil elastase because MPO generates reactive oxidant species as part of its function in innate host defense mechanisms, and is considered by many a marker of oxidative stress." "While the antioxidant supplement did not appear to exert sustained anti-inflammatory effects, we believe its effect on time to first pulmonary exacerbation was significant and clinically meaningful," Dr. Sagel said, adding that the improvement in antioxidant status alone may justify its use. "Developing safe and effective anti-inflammatory treatments remains a key priority of the CF community."   Maternal diets rich in Omega-3 fatty acids may protect offspring from breast cancer Marshall University School of Medicine, June 28, 2021 According to researchers at Marshall University, a maternal diet rich in Omega-3 fatty acids protects from breast cancer development in offspring. In a new studyrecently published by Frontiers in Cell and Developmental Biology, researchers noted a significant difference in mice from mothers that were fed a diet rich in canola oil, compared with mothers fed a diet rich in corn oil. A maternal Omega 3-rich diet affected genome-wide epigenetic landscape changes in offspring and potentially modulated gene expression patterns. Dr. Ata Abbas, a former postdoctoral research fellow in Marshall's Department of Biological Sciences, headed a research team under the leadership of Dr. Philippe Georgel in the College of Science. Research was done in the Cell Differentiation and Development Center at Marshall as part of a collaborative effort with the Joan C. Edwards School of Medicine's Department of Biochemistry and Microbiology, under the leadership of Dr. W. Elaine Hardman. Researchers noticed a three-week delay in mortality in mice whose mothers were fed canola oil versus corn oil. The early delay in mortality was significantly different, but the ultimate overall survival rate was not. Eventually, all the mice developed tumors, but the ones fed canola oil had tumors that were slower-growing and smaller than the mice fed corn oil. Translated to human time scale, the duration of the protective effect linked to the maternal diet would be equivalent to several months (Sengupta et al., 2016). This study is among a body of work done by Marshall University scientists and others looking at the link between Omega-3 fatty acids and reduced incidence of various types of cancer including, but not restricted to, Chronic Lymphocytic Leukemia and Diffuse Large B-Cell Lymphoma. "The issue of parental diet and inter-generational transmission has become an important field of research; however, the mode of action often remains partially elusive," said Georgel, a professor in the Department of Biological Sciences at Marshall. "The MU research group focused on 'epigenetic' aspects of trans-generational transmission to explain the reported role of Omega-3 fatty acids. Epigenetics involves changes in gene expression which are not linked to changes in genetic sequences. These results have the potential to promote the design of simple changes in diet which would allow for reduced onset of various types of cancer, not only for the individuals using that diet but also for their offspring."     Compounds found in green tea and wine may block formation of toxic metabolites Tel Aviv University (Israel), July 2, 2021 A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine. Most people with inherited metabolic disorders are born with a defective gene that results in a critical enzyme deficiency. In the absence of a cure, many patients with inborn congenital metabolic disorders must adhere to a strict and demanding diet their entire lives. This new research finds that certain compounds found naturally in green tea and red wine may block the formation of toxic metabolites. The research was led by Prof. Ehud Gazit of TAU's Faculty of Life Sciences and his doctoral student Shira Shaham-Niv. It was published in the Nature group journal Communications Chemistry. The researchers considered two compounds: (1) epigallocatechin gallate, known as EGCG, found naturally in green tea, which has attracted attention within the medical community for its potential health benefits; and (2) tannic acid, found in red wine, which is known to prevent the formation of toxic amyloid structures that cause neurodegenerative disorders such as Alzheimer's and Parkinson's disease. "In the case of inborn congenital metabolic diseases, the body does not produce a vital metabolic enzyme," Shaham-Niv said. "As a result, metabolites -- substances that are, among other things, the building blocks of DNA and proteins -- accumulate in the body. Such uncontrolled accumulation is toxic and can cause severe developmental and mental disorders. "Our new study demonstrates once again the ability of nature to produce the best candidate of drugs to treat some of the worst human maladies." Collectively, this group of disorders constitutes a significant portion of pediatric genetic diseases. The disease phenylketonuria (PKU), which produces the aggregation of the metabolite phenylalanine, is one common inborn metabolic disease. Infants with PKU must adhere to a strict diet free of phenylalanine for the rest of their lives. If they don't, they may face severe debilitating developmental problems. "But this is an incredibly difficult task, since phenylalanine is found in most of the food products that we consume," Shaham-Niv said. "The avoidance of certain substances is the only way to prevent the debilitating long-term effects of inborn congenital metabolic disorders. We hope that our new approach will facilitate the development of new drugs to treat these disorders." The new research is based on two previous studies conducted at Prof. Gazit's TAU laboratory. In the first study, phenylalanine was shown to be capable of self-assembly and of forming amyloid structures like those seen in Alzheimer's, Parkinson's and other neurodegenerative diseases. In the second study, by Shaham-Niv, other metabolites that accumulate in other inborn congenital metabolic diseases were also shown to undergo self-assembly processes and form toxic amyloid aggregates. "Both studies led to an overhaul in the research community's understanding of metabolic diseases," Shaham-Niv said. "In our new study, we examined whether the molecules identified in past studies on Alzheimer's disease and other amyloid diseases, which are known to inhibit the formation of amyloid aggregates, could also help counteract the amyloid formation process of metabolites in metabolic diseases." The new research focused on EGCG and tannic acid using test tubes and culture cell systems. The two substances were tested on three metabolites related to three innate metabolic diseases: adenine, cumulative tyrosine and phenylalanine. The results were promising. Both tannic acid and EGCG were effective in blocking the formation of toxic amyloid structures. The researchers also used computer simulations to verify the mechanism driving the compounds. "We are entering a new era of understanding the role and the importance of metabolites in various diseases, including metabolic diseases, neurodegenerative diseases and even cancer," Shaham-Niv concluded. "The tools we have developed are ground-breaking and have tremendous potential to help a wide range of patients in the future."       People with fibromyalgia are substituting CBD for opioids to manage pain University of Michigan, June 24, 2021 Fibromyalgia is one of many chronic pain conditions that remains stubbornly difficult to treat.  As the ravages of the opioid epidemic lead many to avoid these powerful painkillers, a significant number of people with fibromyalgia are finding an effective replacement in CBD-containing products, finds a new Michigan Medicine study.  CBD, short for cannabidiol, is the second most common cannabinoid in the cannabis plant, and has been marketed for everything from mood stabilization to pain relief, without the intoxicating effects produced by the most common cannabinoid, THC. THC, which stands for delta-9-tetrahydrocannabinol, is the ingredient in marijuana that causes people to feel high. The cannabis industry has exploded, aided by the legalization of medical and recreational marijuana in states around the United States and the removal of hemp-derived CBD from Schedule 1 status--reserved for drugs with no currently accepted medical use and a high potential for abuse--at the federal level.  Previous research shows that some people substitute medical cannabis (often with high concentrations of THC) for opioids and other pain medications, reporting that cannabis provides better pain relief and fewer side effects. However, there is far less data on CBD use. "CBD is less harmful than THC, as it is non-intoxicating and has less potential for abuse," said Kevin Boehnke, Ph.D., a research investigator in the Department of Anesthesiology and the Chronic Pain and Fatigue Research Center. "If people can find the same relief without THC's side effects, CBD may represent a useful as a harm reduction strategy." Boehnke and his team surveyed people with fibromyalgia about their use of CBD for treatment of chronic pain.  "Fibromyalgia is not easy to treat, often involving several medications with significant side effects and modest benefits," Boehnke explained. "Further, many alternative therapies, like acupuncture and massage, are not covered by insurance." For this study, the team focused on 878 people with fibromyalgia who said they used CBD to get more insight into how they used CBD products.  The U-M team found that more than 70% of people with fibromyalgia who used CBD substituted CBD for opioids or other pain medications. Of these participants, many reported that they either decreased use or stopped taking opioids and other pain medications as a result.  "I was not expecting that level of substitution," said Boehnke, noting that the rate is quite similar to the substitution rate reported in the medical cannabis literature. People who said they used CBD products that also contained THC had higher odds of substitution and reported greater symptom relief. Yet the finding that products containing only CBD also provided pain relief and were substituted for pain medications is promising and merits future study, noted Boehnke.  The team noted that much of the widespread use of CBD is occurring without physician guidance and in the absence of relevant clinical trials. "Even with that lack of evidence, people are using CBD, substituting it for medication and doing so saying it's less harmful and more effective," he said.  Boehnke stressed the need for more controlled research into how CBD may provide these benefits, as well as whether these benefits may be due to the placebo effect.  Clinically, opening up lines of discussion around CBD use for chronic pain is imperative, said Boehnke, for medication safety reasons as well as for "enhancing the therapeutic alliance and improving patient care."

四大排毒系統我們該注意什麼？ 營養補充之後會有什麼轉變？ PM2.5原來會讓人變胖？ 致胖因子對身體有什麼影響？ 環境中的毒素，我們該怎麼避免？

This is Vaccine 411, the latest coronavirus vaccine information for June 28th, 2021.The delta variant continues to turn back the clock. Moscow had a record 144 deaths in 24 hours yesterday. Germany declared Portugal a “virus-variant zone”, banning most arrivals from that country and is trying to ban British travelers from all EU countries regardless of vaccination status. Greece warned strict local lockdowns may be needed over the summer in some areas. Indonesia recorded a new high in daily cases, with similar spikes in Thailand and Malaysia. Sydney, Australia began a two-week lockdown. New Zealand suspended its quarantine-free travel corridor with Australia. Israel has reimposed mask requirements in enclosed public places. And in Africa, where vaccinations have been minimal, cases have jumped 25% over the last week.How can the U.S. get its vaccination numbers up now that they've stalled out? The White House thinks it's something called the “movable middle.” That's people who are unvaccinated, but still might be able to be convinced. And they're using political campaign tactics to identify, reach, and win over those people. What the White House won't do is promise we'll ever know for sure the real origin of the pandemic that's killed at least 3.9 million people. They say their review may not produce a definitive explanation. Although knowing the origin is critical to avoiding or preparing for future such catastrophes, governments, the media, and science organizations could leave us with no answers at all.Far more states have banned proof-of-vaccination policies than have created programs for people to digitally show their vaccination status. Hawaii is the only state enforcing some version of a vaccine passport. And only California, New York, and Louisiana have offered residents a way to voluntarily show proof of vaccination.Nothing's ever good enough. NASA reports the COVID-19 pandemic and its lockdowns got rid of a lot of pollution around the world…but not all of it. They cite tiny airborne particles called PM2.5 as something that didn't change much. These are produced by both human activity and natural processes and are associated with several effects on health. In the United States cases were down 18%, deaths are down 15%, and hospitalizations are down 15% over 14 days. The 7-day average of new cases has been trending flat since June 18. There are now 4,947,918 active cases in the United States. The top 10 counties with the highest number of recent cases per capita according to The New York Times: Dimmit, TX. Reeves, TX. Campbell, VA. Clay, NC. Franklin, TX. Panola, TX. Upshur, TX. Joplin, MO. Dallas, MO. And Taney, MO. There have been 603,966 deaths in U.S. recorded as Covid-related.The states with the most new deaths reported as COVID-related: California 31. New York 14. Pennsylvania 11. Texas 9. Utah 8. Virginia 5. Minnesota 4. New Jersey and Maryland 3. And Iowa 2. The vaccinating states update will be coming tomorrow, those numbers are not updated over the weekend.The top 5 countries for vaccinations per capita are Gibraltar, the United Arab Emirates, Malta, Seychelles, and the Cayman Islands. The bottom five are Chad, the Democratic Republic of Congo, Burkina Faso, Benin, and South Sudan.Globally, cases were down 6% and deaths down 28% over 14 days, with the 7-day average trending down since June 26. There are now 11,547,517 active cases around the world.The five countries with the most new cases: India 46,643. Brazil 33,704. Colombia 32,376. Indonesia 21,342. And Russia 20,538. There have now been 3,922,005 deaths reported as Covid-related worldwide. For the latest updates, subscribe for free to Vaccine 411 on your podcast app or ask your smart... See acast.com/privacy for privacy and opt-out information.

This is Coronavirus 411, the latest COVID-19 info and new hotspots… Just the facts… for June 28th, 2021.The delta variant continues to turn back the clock. Moscow had a record 144 deaths in 24 hours yesterday. Germany declared Portugal a “virus-variant zone”, banning most arrivals from that country and is trying to ban British travelers from all EU countries regardless of vaccination status. Greece warned strict local lockdowns may be needed over the summer in some areas. Indonesia recorded a new high in daily cases, with similar spikes in Thailand and Malaysia. Sydney, Australia began a two-week lockdown. New Zealand suspended its quarantine-free travel corridor with Australia. Israel has reimposed mask requirements in enclosed public places. And in Africa, where vaccinations have been minimal, cases have jumped 25% over the last week.How can the U.S. get its vaccination numbers up now that they've stalled out? The White House thinks it's something called the “movable middle.” That's people who are unvaccinated, but still might be able to be convinced. And they're using political campaign tactics to identify, reach, and win over those people. What the White House won't do is promise we'll ever know for sure the real origin of the pandemic that's killed at least 3.9 million people. They say their review may not produce a definitive explanation. Although knowing the origin is critical to avoiding or preparing for future such catastrophes, governments, the media, and science organizations could leave us with no answers at all.Far more states have banned proof-of-vaccination policies than have created programs for people to digitally show their vaccination status. Hawaii is the only state enforcing some version of a vaccine passport. And only California, New York, and Louisiana have offered residents a way to voluntarily show proof of vaccination.Nothing's ever good enough. NASA reports the COVID-19 pandemic and its lockdowns got rid of a lot of pollution around the world…but not all of it. They cite tiny airborne particles called PM2.5 as something that didn't change much. These are produced by both human activity and natural processes and are associated with several effects on health. In the United States cases were down 18%, deaths are down 15%, and hospitalizations are down 15% over 14 days. The 7-day average of new cases has been trending flat since June 18. There are now 4,947,918 active cases in the United States. The top 10 counties with the highest number of recent cases per capita according to The New York Times: Dimmit, TX. Reeves, TX. Campbell, VA. Clay, NC. Franklin, TX. Panola, TX. Upshur, TX. Joplin, MO. Dallas, MO. And Taney, MO. There have been 603,966 deaths in U.S. recorded as Covid-related.The states with the most new deaths reported as COVID-related: California 31. New York 14. Pennsylvania 11. Texas 9. Utah 8. Virginia 5. Minnesota 4. New Jersey and Maryland 3. And Iowa 2. The vaccinating states update will be coming tomorrow, those numbers are not updated over the weekend.The top 5 countries for vaccinations per capita are Gibraltar, the United Arab Emirates, Malta, Seychelles, and the Cayman Islands. The bottom five are Chad, the Democratic Republic of Congo, Burkina Faso, Benin, and South Sudan.Globally, cases were down 6% and deaths down 28% over 14 days, with the 7-day average trending down since June 26. There are now 11,547,517 active cases around the world.The five countries with the most new cases: India 46,643. Brazil 33,704. Colombia 32,376. Indonesia 21,342. And Russia 20,538. There have now been 3,922,005 deaths reported as Covid-related worldwide. For the latest updates, subscribe for free to Coronavirus 411 on your podcast... See acast.com/privacy for privacy and opt-out information.

Show #1095. If you get any value from this podcast please consider supporting my work on Patreon here. Plus all Patreon supporters get their own unique ad-free podcast feed. Good morning, good afternoon and good evening wherever you are in the world, welcome to EV News Daily for Thursday 27th May. It’s Martyn Lee here and I go through every EV story so you don't have to. Thank you to MYEV.com for helping make this show, they’ve built the first marketplace specifically for Electric Vehicles. It’s a totally free marketplace that simplifies the buying and selling process, and help you learn about EVs along the way too. U.S. STEPS CLOSER TO NEW $12,500 EV TAX CREDIT"The US Senate Finance Committee on Wednesday approved a bill to increase the tax credit for electric vehicles assembled by union workers in the US up to $12,500. This would apply to electric vehicles up to a price of $80,000." reports Chris Randall at Electrive: "The new law would remove this existing cap, but a different, future limit is included in the proposal: For example, the tax credit would be phased out over a three-year period once 50 per cent of car sales in the US are electric cars. Now for the proposed increase in the credit up to $12,500: The proponents of the bill, led by Democratic Senator Debbie Stabenow of Michigan, propose to increase the $7,500 tax credit by $2,500 for vehicles assembled in the US and by another $2,500 for vehicles manufactured in plants whose employees are members of or represented by a union." Yahoo! News points out: “That would mean smaller credits to automakers such as Tesla, Volkswagen and others who do not have U.S. union workers, and companies building EVs outside the United States. The EV incentives are estimated to cost $31.6 billion through 2031, according to a congressional estimate. The bill must still be approved by the full Senate and U.S. House of Representatives. The bill also includes a 30% tax credit for manufacturers to retool or build new facilities to produce advanced energy technologies including batteries and new incentives to purchase commercial electric vehicles." https://www.electrive.com/2021/05/27/us-senate-approves-increase-of-ev-tax-credit/ https://news.yahoo.com/u-senate-panel-advances-ev-025709643.html RIVIAN DELAYS DELIVERIES OF THE R1T LAUNCH EDITION BY ONE MONTH"Rivian said that deliveries of the R1T Launch Edition, the limited edition release of its first series of “electric adventure vehicles,” will be delayed by a month, according to an update on its website." reports Tech Crunch: "Customers who preordered can now expect to start receiving their pickup trucks in July instead of June, with Launch Edition deliveries to be completed by Spring 2022. The change was first spotted by the Rivian Forum. The one-month delay was due to a combination of small issues, including delays on shipping containers, the ongoing chip shortage as well as ensuring the servicing piece is properly set up, a Rivian spokesperson said." https://techcrunch.com/2021/05/27/rivian-delays-deliveries-of-the-r1t-launch-edition-by-one-month/ FORMER WAYMO FINANCE CHIEF DWYER JOINS EV STARTUP RIVIAN"Rivian Automotive Inc., the electric-vehicle startup backed by Amazon.com Inc., has hired a former finance chief from Alphabet Inc.’s self-driving arm Waymo LLC. Gerard Dwyer, who was Waymo’s chief financial officer, joined Rivian this week as vice president of business finance, according to a post on LinkedIn." says Bloomber: "Waymo, long viewed as the leader among autonomous-driving startups, is seeking to raise as much as $4 billion from outside investors and also considering an IPO, Bloomberg reported last week, citing people familiar with the plans." https://www.bloomberg.com/news/articles/2021-05-27/former-waymo-finance-chief-dwyer-joins-ev-start-up-rivian FIRST ALL-ELECTRIC GOOGLE STREET VIEW CAR IS A JAGUAR I-PACE"For the past few years, Google has equipped its mapping vehicles with air pollution sensors. Google worked with Jaguar Land Rover on the first all-electric Street View car that will be tasked with measuring air quality in Dublin, Ireland." says 9to5Mac: "A Jaguar I-Pace is being used for this effort, and it will see a roof mounting for the tall Street View camera, as well as a new rear-window glass for wiring and redesigned interior switchgear for sensor controls. The visual system was last updated in 2017 to provide higher-resolution images while being less bulky. The vehicle will also be equipped with Aclima mobile air sensors that record nitrogen dioxide (NO2) and carbon dioxide (CO2) emissions, as well as fine particles (PM2.5). Meanwhile, Google is partnering with the Dublin City Council on the Environmental Insights Explorer tool that provides local data on air quality." https://9to5google.com/2021/05/25/electric-google-street-view-car/ FIRST RIDE IN THE ELECTRIC LUCID AIR SEDAN "The ride was comfortable, and while the Air makes the low-speed pedestrian noises all EVs are required to make, nothing is piped into the cabin. That means riding in an Air is a mostly calm and serene experience, at least until the driver floors the throttle. After my first encounter back in 2017, I was impressed with how well-built the Air was. Despite being an alpha prototype, everything I poked or prodded worked, including the three screens and their UI. But the car I rode in this past weekend felt like a huge step beyond that earlier experience in every regard." writes ArsTechnica: "Lucid is currently building a batch of 70 preproduction cars, with another run of 100 that, among other things, will be used for PR and marketing. And I can't tell you how curious I am to drive one of them." https://arstechnica.com/cars/2021/05/we-got-our-first-ride-in-the-electric-lucid-air-sedan/ HYUNDAI IONIQ 5 SUBSCRIPTION WILL LET EV INTENDERS TRY BEFORE THEY BUY"Although Hyundai hasn’t yet announced a base price or price range for the 2022 Ioniq 5 electric vehicle, it’s already suggested that a new subscription plan will be one of the ways you can get behind the wheel of this very intriguing EV.  Hyundai Motor America on Monday said that in their research they found that what it terms “mobility pioneers”—people more eager to try electric vehicles—were used to using subscription services in many parts of their life." according to Green Car Reports: "This is Hyundai’s second try offering an electric car under a subscription plan. In 2017 and 2018 it offered the Ioniq Electric with an “Ioniq Unlimited” program—focused toward cost-conscious Millennials—that folded charging costs, scheduled maintenance, and even replacement costs of wear items into a single monthly payment. Although Hyundai won’t detail the program until later in the year, there are already two key differences. This time, it’s intended for intervals as short as one to three months, and it’s aimed at a more affluent crowd—just those who want to try before they buy." https://www.greencarreports.com/news/1132386_hyundai-ioniq-5-subscription-will-let-ev-intenders-try-before-they-buy TESLA LOSES U.S. DESIGNATION FOR SOME ADVANCED SAFETY FEATURES"Newer Tesla Model 3 and Model Y vehicles will no longer be labeled as having some advanced safety features after the automaker said it was removing radar sensors to transition to a camera-based Autopilot system, the National Highway Traffic Safety Administration (NHTSA) said Wednesday." reports Automotive NEws: "The U.S. agency confirmed it updated its website to show that Tesla Model 3 and Model Y vehicles produced on or after April 27 "do not have NHTSA's check mark for recommended safety technologies: forward collision warning, lane departure warning, crash imminent braking and dynamic brake support." The agency said it "only includes check marks for the model production range for the vehicles tested." The NHTSA's five-star crash ratings website includes check marks for up to four recommended advanced safety technologies." https://europe.autonews.com/automakers/tesla-loses-us-designation-some-advanced-safety-features EVGO LAUNCHES RESERVATIONS CHARGING PROGRAM ON US WEST COAST"Public fast-charging network EVgo has announced a new program called EVgo Reservations that gives drivers the freedom to claim their spot at a charger ahead of time. The initial rollout consists of 17 locations across California and the Seattle area in a pilot program that has already expanded." says electrek: "In a recent press release, EVgo announced 17 locations that now feature the new EVgo Reservations program. The company’s software team developed this new feature by integrating various makes and. models of EV fast chargers with its own back-end software system. As a result, drivers can now make a reservation at a charger of their choice while en route, or up to two weeks in advance" https://electrek.co/2021/05/26/evgo-launches-reservations-charging-program-on-us-west-coast/ AUDI A4 RANGE TO BE TOPPED BY ELECTRIC"Audi’s finalised plans for the all-new A4 include an electric-only four-wheel-drive performance RS model and a hybrid RS4" says Autocar: "Set to challenge the Tesla Model 3 and newly unveiled BMW i4, it is based around the Premium Platform Electric (PPE) architecture that has been developed in a joint engineering programme between Audi and Volkswagen Group sibling company Porsche. The PPE platform used by the A4 E-tron will be shared with the upcoming Audi Q6 E-tron, as well as an electric version of the second generation Macan currently under development at Porsche. The line-up will be crowned by an electric RS performance model from the Audi Sport division, packing up to 469bhp" https://www.autocar.co.uk/car-news/new-cars/new-2023-audi-a4-range-be-topped-electric-and-hybrid-rs-duo QUESTION OF THE WEEK WITH EMOBILITYNORWAY.COM Do you have an opinion on hydrogen power for personal transport? Yes or No, both good answers, and if yes then what do you think? Email me your thoughts and I’ll read them out on Sunday – hello@evnewsdaily.com   It would mean a lot if you could take 2mins to leave a quick review on whichever platform you download the podcast. And  if you have an Amazon Echo, download our Alexa Skill, search for EV News Daily and add it as a flash briefing. Come and say hi on Facebook, LinkedIn or Twitter just search EV News Daily, have a wonderful day, I’ll catch you tomorrow and remember…there’s no such thing as a self-charging hybrid. PREMIUM PARTNERSPHIL ROBERTS / ELECTRIC FUTURE BRAD CROSBYPORSCHE OF THE VILLAGE CINCINNATIAUDI CINCINNATI EASTVOLVO CARS CINCINNATI EAST NATIONALCARCHARGING.COM and ALOHACHARGE.COM DEREK REILLY FROM THE EV REVIEW IRELAND YOUTUBE CHANNELRICHARD AT RSEV.CO.UK – FOR BUYING AND SELLING EVS IN THE UKEMOBILITYNORWAY.COM/

Hablamos sobre la relación directa que existe entre vivir en lugares con niveles altos de PM2. 5 en espacios abiertos y el deterioro de la memoria episódica. Aproximadamente entre un 10% y un 20% de la pérdida de memoria podría achacarse a una reducción de la masa cerebral similar a la provocada por el alzhéimer.

   If you appreciate great politicians, you have to admire the brilliance of Kansas City Mayor Quinton Lucas.  At just 36, he has his sights set on the Senate and of course, the White House.  He's so good he can defund the police in secrecy in just two hours with a Council vote and then turn around and go on Fox News and convince some Republicans he didn't defund the police and he stands for local and smaller government.  Some people are mad, but most people just buy what he's selling.    Patrick Mahomes wants a chip in the ball to decide touchdowns when it crosses the goal line.  Did you know there is already a chip on the ball?  We tell you why it's in there and discuss if PM2's goal line idea is a good one.    The Royals and Tigers are both on winning streaks as a three game set begins at the K.  The Royals are doing it with a a better bullpen, the Tigers got a no hitter this week.  And Adelberto Mondesi is close to returning... what are we waiting for?    And Dodgers lefty Clayton Kershaw says 6 no hitters so far this year is bad for baseball and makes a great case why.

พายุเข้า น้ำท่วม ดินถล่ม ไฟป่า ฝุ่น PM2.5 ใครมันเป็นคนบอกว่าประเทศไทยมีภัยพิบัติน้อยกันนะ วันนี้เราเลยชวนหมิง มาถกเถียงกันเกี่ยวกับเรื่องภัยพิบัติและสิ่งแวดล้อม ภัยพิบัติในไทยมีอะไรบ้าง ส่วนใหญ่ภัยพิบัติเกิดจากอะไร มาตรการการป้องกันทั้งไทยและเทศ รวมถึงการจัดการกับปัญหาสิ่งแวดล้อม เครื่องดื่มวันนี้อุดมไปด้วยปัญหา ขบเคี้ยวและขบคิดขณะรับรสนะครับ

Researchers at the University of California, San Francisco found that among older adults with cognitive impairment, the greater the air pollution in their neighborhood, the higher the likelihood of the presence of amyloid plaques in their brain. Lead researcher Leonardo Iaccarino, PhD, details his work examining air pollution and brain health outcomes and discusses possible ways individuals and society can lower the impact of air pollution on Alzheimer’s disease risk. Guest: Leonardo Iaccarino, PhD, University of California San Francisco Memory and Aging Center   Episode Topics: What sparked your interest in neuroscience and Alzheimer's disease research? 1:06 Why is your research so pivotal? 2:21 What was the IDEAS Study? 4:12 What kinds of air pollution are you referring to? 6:09 What can generate PM2.5? 7:45 Are cars or factories potential sources? 8:50 How does air pollution increase risk for Alzheimer's disease? 9:15 Is there a further increased risk after long exposure? 11:00 Why is it important that there was no link to ground-level ozone? 12:04 Did you look into the APOE4 genetic risk from air pollution? 14:32 What should people do with this information? 16:19 Is there a way to find your own neighborhood value of PM2.5? 18:44 Do you see any policy or system changes in the future from your findings? 19:55 Do you believe there might be other environmental factors that increase risk? 21:03 What do you do in your life to decrease risk for neurodegeneration? 21:57 Find Dementia Matters online Follow us on Facebook Follow us on Twitter

Tim talks with former Trump/Pence EPA Transition Team Memeber and founder of JunkScience.com Steve Milloy to talk the nonsensical claim that PM2.5 from farms cause over 17 thousand deaths a year. Missouri Secretary of State Jay Ashcroft joins the show.  See omnystudio.com/listener for privacy information.

Mattel lancia un programma per il riciclo dei giocattoli usati. Si chiama 'PlayBack', ed è un'iniziativa che ha la finalità di recuperare e riutilizzare vecchi materiali per la realizzazione di nuovi prodotti. Tra i primi giocattoli ad essere coinvolti nel programma figura anche la mitica Barbie. La nuova iniziativa della multinazionale dei giochi segue l'impegno, da essa preso in precedenza, di utilizzare, entro il 2030, solamente materiali che siano al 100% riciclabili. "Teniamo questi materiali preziosi fuori dalle discariche – afferma una nota della Società - costituendo un'opportunità per sviluppare un modello circolare". “Playback” interesserà inizialmente Stati Uniti e Canada, ma poi il programma sarà esteso all'Europa. Anche il mondo della finanza ha preso coscienza dell'importanza delle questioni inerenti la tutela dell'ambiente e molti investitori cominciano ad orientare i propri capitali verso l'economia green.Intervenendo al G20 Techsprint, organizzato dalla Banca dei Regolamenti Internazionali, il governatore della Banca d'Italia, Ignazio Visco, ha, infatti, rilevato come numerosi risparmiatori stiano cambiando le loro preferenze, optando per strumenti finanziari come i green bond o i social bond. Secondo Visco, il sistema finanziario sta iniziando a supportare la transizione ecologica “con i fondi di investimento che stanno ripensando i loro portafogli”, ma anche “le banche centrali stanno giocando un ruolo interessante” non solo attraverso i loro sostegni finanziari, ma anche “tramite il loro operato di vigilanza”. Così come governi e parlamenti stanno adottando regole e pratiche nella direzione di una transizione e una crescita più sostenibile. Il Governatore ha concluso affermando che i danni che sta provocando il cambiamento climatico e il suo effetto nel modificare l'economia mondiale possono essere affrontati con nuove soluzioni fornite dalla tecnologia, che la finanza ha il dovere di sostenere, poichè quella del cambio climatico è “una sfida globale che va al di là dei confini nazionali” ed affrontarla “è un obiettivo più urgente che mai”Passiamo ora alle novità che ci arrivano dall'UE, per parlarvi della Commissione europea che vuole dimezzare i decessi da smog in dieci anni. E' questo uno degli obiettivi del Piano d'azione "inquinamento zero", presentato ieri a Bruxelles.Il piano, che fa parte del Green Deal, proporrà iniziative legislative e non legislative, organizzate e coordinate per azzerare l'inquinamento dell'aria, dei fiumi e dei suoli in Europa. Secondo gli ultimi dati dell'Agenzia Ue per l'ambiente, solo il particolato fine (Pm2.5) è responsabile, annualmente, di 379mila morti nell'Ue, di cui oltre 52mila in Italia.E concludiamo con una nota del ministro dei Trasporti e della Mobilità Sostenibile, Enrico Giovannini, che annuncia la firma del decreto sull'istituzione del mobility manager nelle imprese e nelle istituzioni con oltre di 100 addetti, e non più 300. Ciò significa, spiega il ministro, avere ”l'opportunità di ripensare i tempi della città, i tempi del movimento, delle scuole e delle persone. Non dobbiamo solo inseguire i cambiamenti, ma possiamo gestire questo elemento che incide moltissimo sulla qualità della vita”.

Mattel lancia un programma per il riciclo dei giocattoli usati. Si chiama 'PlayBack', ed è un'iniziativa che ha la finalità di recuperare e riutilizzare vecchi materiali per la realizzazione di nuovi prodotti. Tra i primi giocattoli ad essere coinvolti nel programma figura anche la mitica Barbie. La nuova iniziativa della multinazionale dei giochi segue l'impegno, da essa preso in precedenza, di utilizzare, entro il 2030, solamente materiali che siano al 100% riciclabili. "Teniamo questi materiali preziosi fuori dalle discariche – afferma una nota della Società - costituendo un'opportunità per sviluppare un modello circolare". “Playback” interesserà inizialmente Stati Uniti e Canada, ma poi il programma sarà esteso all'Europa. Anche il mondo della finanza ha preso coscienza dell'importanza delle questioni inerenti la tutela dell'ambiente e molti investitori cominciano ad orientare i propri capitali verso l'economia green. Intervenendo al G20 Techsprint, organizzato dalla Banca dei Regolamenti Internazionali, il governatore della Banca d'Italia, Ignazio Visco, ha, infatti, rilevato come numerosi risparmiatori stiano cambiando le loro preferenze, optando per strumenti finanziari come i green bond o i social bond. Secondo Visco, il sistema finanziario sta iniziando a supportare la transizione ecologica “con i fondi di investimento che stanno ripensando i loro portafogli”, ma anche “le banche centrali stanno giocando un ruolo interessante” non solo attraverso i loro sostegni finanziari, ma anche “tramite il loro operato di vigilanza”. Così come governi e parlamenti stanno adottando regole e pratiche nella direzione di una transizione e una crescita più sostenibile. Il Governatore ha concluso affermando che i danni che sta provocando il cambiamento climatico e il suo effetto nel modificare l'economia mondiale possono essere affrontati con nuove soluzioni fornite dalla tecnologia, che la finanza ha il dovere di sostenere, poichè quella del cambio climatico è “una sfida globale che va al di là dei confini nazionali” ed affrontarla “è un obiettivo più urgente che mai” Passiamo ora alle novità che ci arrivano dall'UE, per parlarvi della Commissione europea che vuole dimezzare i decessi da smog in dieci anni. E' questo uno degli obiettivi del Piano d'azione "inquinamento zero", presentato ieri a Bruxelles. Il piano, che fa parte del Green Deal, proporrà iniziative legislative e non legislative, organizzate e coordinate per azzerare l'inquinamento dell'aria, dei fiumi e dei suoli in Europa. Secondo gli ultimi dati dell'Agenzia Ue per l'ambiente, solo il particolato fine (Pm2.5) è responsabile, annualmente, di 379mila morti nell'Ue, di cui oltre 52mila in Italia. E concludiamo con una nota del ministro dei Trasporti e della Mobilità Sostenibile, Enrico Giovannini, che annuncia la firma del decreto sull'istituzione del mobility manager nelle imprese e nelle istituzioni con oltre di 100 addetti, e non più 300. Ciò significa, spiega il ministro, avere ”l'opportunità di ripensare i tempi della città, i tempi del movimento, delle scuole e delle persone. Non dobbiamo solo inseguire i cambiamenti, ma possiamo gestire questo elemento che incide moltissimo sulla qualità della vita”.

本節新聞重點： ▲週日華南雲系水氣移入 中南部山區將下雷陣雨 ▲空汙入侵 中研院：溪頭芬多精被轉化為PM2.5 ▲台北信義區山坡遭民眾占用種菜 晚間竄火 ▲英國女王95歲生日 罕見發聲明「感謝祝福」 ▲針對中國大使？ 巴基斯坦酒店爆炸4死12傷 ▲拜登提名 對中鷹派瑞特納出任印太事務助理部長 台視新聞每日提供您最專業的新聞頭條 ｜更多新聞｜ ◎台視新聞訂閱→https://www.youtube.com/c/ttvnewsview ◎台視直播訂閱→https://www.youtube.com/c/twlivenews ◎台視臉書粉絲團訂閱→https://www.facebook.com/ttvnews/ ◎台視新聞IG訂閱→https://www.instagram.com/ttvnews_tw/

*方格子專題▶ https://vocus.cc/bluepigeonnn/introduce *蒼藍鴿使用的保健品牌「藥師健生活」: 輸入折扣碼「bluepigeon」享全品項9折優惠! 點我購買▶ https://reurl.cc/N6Mb86 *本集主題：空氣汙染、空汙、霾害、碳水化合物、低醣飲食、低碳飲食、生酮飲食、腎結石、高血脂、外科口罩、PM2.5口罩 *更多醫學知識： 蒼藍鴿著作▶ https://ppt.cc/ffUrkx Instagram▶ https://reurl.cc/ygvba8 Youtube▶ https://reurl.cc/gm6bb7 *支持蒼藍鴿產出Podcast： https://pay.firstory.me/user/bluepigeon0810 Powered by Firstory Hosting

  Vidcast:  https://youtu.be/PlrPYrQW38M   Rising concentrations of particulate pollutants in the air is directly associated with a rise in CoVid infections.  Researchers in Hong Kong, Britain, and Israel draw this conclusion after analyzing data from 18 Chinese provincial capital cities including Wuhan.   Pooling data from all studied cities, there was a significant trend between concentration of 2.5 micron particulate matter in the air, known as PM2.5, and the rate of change in CoVid infections.  Looking only at the numbers from Wuhan, the epicenter of the Chinese CoVid epidemic, the effect of air pollution on CoVid infection rates was even more dramatic.   This study suggests that air pollution as well as population density is driving CoVid spread.   https://www.medrxiv.org/content/10.1101/2020.05.19.20106484v3.full.pdf+html   #CoVid #pandemic #pollution #china  

A new report from air technology company IQAir concludes that despite an 11% reduction in PM2.5 levels, India emerged as the world's third-most polluted country. India's air quality has serious ramifications for both public health and the economy at large. Shambhavi Naik and Sunila Dixit discuss the findings of the report and India's existing policies for curbing air pollution.You can follow Shambhavi on twitter: @TheNaikMic(TheNaikMic)You can follow Sunila on twitter: @SunilaDixit(SunilaDixit)You can listen to this show and other awesome shows on the IVM Podcasts app on Android: https://ivm.today/android or iOS: https://ivm.today/ios, or any other podcast app.

长久以来，我们会把沙尘暴翻译为Sandsturm。但仔细想想，沙和尘并非同一事物。比如我们说“雾霾天”的时候，主要指的是空气中的PM2.5（即直径大于2.5微米的颗粒）超标。涉及德语表达：雾霾：der SmogPM 2.5：Partikel mit einem Durchmesser von 2,5 Mikrometern简称der Feinstaub而这次的天气我们不会想到雾霾天（虽然PM 2.5同样爆表了），是因为PM 10成了主导：这里的PM 10≈沙。根据德语维基百科，如果风暴卷起的主要是细颗粒物，那么就是尘暴Staubsturm。如果卷起的主要是粗颗粒物，那么就是沙暴Sandsturm。但沙尘不分家，用Sandsturm指代沙尘暴完全可以。风起时沙子和尘土满天飞。风停了，沙子落下来，空气里都是浮尘Schwebstaub。今年2月份，欧洲出现罕见的沙尘天气，瑞士还下了血雪（Blutschnee），是风带去了来自撒哈拉的问候。而这次侵犯北京的沙尘，来自蒙古国。而在德文维基Sandsturm的词条下，治理沙尘暴的手段，只有我们的“三北防护林”上榜：Mit der Errichtung der Grünen Mauer versucht China die Sandstürme einzudämmen, die regelmäßig Peking heimsuchen. Insgesamt wollen die Chinesen bis zum Jahr 2050 eine Fläche von 4 Millionen Quadratkilometer Land – eine Fläche zehnmal größer als Deutschland – mit Bäumen bepflanzen. Damit ist die Grüne Mauer das größte Aufforstungsprojekt der Menschheitsgeschichte.其中，三北防护林：das „Drei-Norden-Schutzwald-Projekt“die Grüne Mauer / der Schutzwald Chinas an der Grenze zu den Wüsten不过，三北和萨赫勒的绿色长城这次都失手了...峥哥截稿（11.15 Uhr）时，北京浮尘尚未好转。

stories by: 1: u/azaleah_Someone always rings my doorbell at exactly 11:05 PM2:u/outworlder39Church in the Woods 3:u/insidebeegeeStalked at work until I turned 18 u/ValyrianJediA strange man hunted me through a national parkThanks to everyone for hanging with us in season 2! Don’t forget to subscribe, rate, and review everywhere you can!ALSO join the facebook group We Drink and We Know Things PODCAST email us @ wedrinkandweknowthingspodcast@gmail.com

อัปเดตข่าว Mission News ประจำวันพุธที่ 10 มีนาคม 2021 . [ในประเทศ] แชมป์ที่ไม่อยากเป็น! เชียงใหม่ครองอันดับหนึ่ง PM2.5 สูงสุดในโลก [ต่างประเทศ] SpaceX เล็งเชื่อมต่อยานพาหนะกับ Starlink เพื่อเก็บข้อมูล [ต่างประเทศ] นักวิเคราะห์คาด! เศรษฐกิจอินเดียเติบโตพุ่ง 12.6% [ต่างประเทศ] ‘บักกิงแฮม’ แถลงถึงกรณีเจ้าชายแฮร์รี และเมแกนออกรายการของโอปราห์ วินฟรีย์ . พิเศษ! แจกรางวัลสำหรับแฟนๆ Mission News ทุกวันศุกร์ อย่าลืมรับชมและร่วมสนุกกันนะครับ . #MissionNews #MissionToTheMoonPodcast

【本日新聞】 ．【台股暴跌】華航運價續漲爆百萬張天量　股價逆勢創5年半新高 ．101大樓遭霾蓋成PM2.5指標　台北「紅害」禍首來自境內中部污染 ．中國因介殼蟲禁台灣鳳梨 陳吉仲斥不符國際貿易規範 ．美眾院外委會通過法案 阻中國靠2022冬奧洗白形象 #中國禁鳳梨​ #空汙​ #2022北京冬奧

Altruistic/Altruism-Is the principle and moral practise of concern for the happiness of other human beings, resulting in a quality of life. Growing up in Brooklyn, we called ourselves Brooklynites. The good people of the proud borough are always looking out for our neighbours and individuals in our community. Here in NY, we are tough and resilient and more importantly, humbled to lend a helping hand in a time of need. So rightfully so we named our foundation "Altrunite". Our mission, like our masks, is a symbol of the unselfish act to protect others. Some may not know that wearing a mask is not necessary to protect themselves, but rather others around them if in case they are with, or without knowledge get infected with this terrible virus. We want to take a stand to stop the spread of Covid-19 by teaming up with sports fans along with sports personalities within our great state of NY and its surrounding areas to promote and distribute quality handmade masks. We are not looking for profits, only protection and assistance to others. Together, fans, along with former and current sports players and staff can make a positive impact to save lives within our industry and beyond. Our Face Masks for Fans project began at the start of the Corona Virus pandemic in early March 2020. When masks were an absolute necessity, but products were scarce, we teamed up with professional seamstresses working at mom-and-pop tailor shops in Brooklyn, NY. We decided to utilize our own New York Rangers t-shirts directly from our own closet collections and cultivate a mask that can both complement a purpose of protection and fashion. We displayed our masks on a wide variety of social media platforms, selling them to fans and investing all our profits into more materials, and purchasing more shirts online. When demands for our masks began to exceed the number of shirts at hand, we reached out to our group members and fellow NYR fans online. What transpired next would be a true statement that hockey fans are simply the greatest. To date over 1,200 shirts and jerseys donated to us to continue our cause; allowing us to further expand our mission, as well as donating masks to essential employees, frontline workers, and first responders. Every shirt and jersey are washed, sanitized, and ironed. Every mask is double-layered, and then a third thin layer is added for a filter pocket. We include a 5-layer PM2.5 activated charcoal filter, which further provides a level of protection. Unlike disposable masks, which at times can be more harmful than beneficial (if worn for a longer period of time) the beauty of our product is that it is made from actual shirts and jerseys, therefore it is 100 per cent washable and reusable. We DO NOT heat-press, or screen print any logos or names. We simply repurpose a fan's once owned shirt/jersey and make it into a mask. We cut, sew, and stitch ONLY. The mask is easy to breathe in and is currently up for a redesign for individuals that wear our mask for hours at a time. Also, we now provide a complimentary pouch for placement of the mask to carry, leave in the car or at home. This will prevent excess dust, debris, or dirt on the mask, and avoid possible misplace and/or loss. While we continue to promote and educate the benefits of wearing a mask in public, this is only one of our current initiatives. We are a non-profit organization. A family of fans charity. For the moment, we are a team of driven and dedicated NYR die-hards in action to striving for a positive cause. Connect with ALTRUNITE: https://www.altrunite.com/ https://www.altrunite.com/our-story/ https://www.altrunite.com/our-blog/ contact@altrunite.com

Will an AirScore become as powerful a deciding factor on whether occupiers take space as rents and lease terms? It is certainly a question that is worth debating, according to AirRated chief executive Francesca Brady and AshbyCapital property director Tom Smithers. AshbyCapital’s The Future Works development in Slough, Berkshire, has just become the UK’s first property to receive a platinum rating from AirRated for its indoor air quality. According to AirRated’s assessment, the 100,000 sq ft building has exceptionally low levels of PM2.5, with levels will below those set by the World Health Organisation. But why does indoor air quality matter? And why are more and more developers looking to get a certification for their buildings? In this episode of the EG Property podcast, Brady and Smithers – with host, EG editor Samantha McClary – discuss what role air quality has to play in the campaign to bring people back to the office, what value it offers to potential occupiers and investors and why it is being asked about in real estate discussions more and more every day.

Diana Hernandez, associate professor of sociomedical sciences at the Columbia University Mailman School of Public Health, and Sybil Hodgson, M.D., physician and medical director of the Montefiore Medical Group West Farms Family Practice, discuss the community health profile of the West Farms section of the Bronx and the health toll of the pandemic in the neighborhood. @BrianLehrer we want a city council person who will fight for Black maternal health to end the crisis in NYC where a Black birthing person is 8-12x more likely to die than white counterpart. Orgs to know @AncientSong7 doula services Ashe Birthing Services community fund — getboober (@getboober) February 11, 2021 Ask the guests how car culture contributes to these conditions, and disinvestment in @NYCParks and street tree plantings and park development contributes to high PM2.5 levels and toxic air. #CongestionPricing. No more free parking. NO, poor folks do not own cars. — Peg Bundy (@aGreenQueenNYC) February 11, 2021 Great to hear about the work being done by fellow Xavier Univ. of LA alum, Dr. Sybil Hodgson. Strong work! - Challon Perry, MD — Challon Perry (@speedracerX008) February 11, 2021 @BrianLehrer Thank you to the current color. I am so sick of people slagging off the Bronx and making it seem like we are just a borough of depressed fat asthmatic animals there is more to us than Riverdale that is cultured — Jaybee (@blackzelig) February 11, 2021

Posebna ugodnost za vse moje drage poslušalke INBED podcasta: uporabi kodo INBEDSILK za 15% popust on nakupu 2+ svilenih mask. Samo do konca 19.2.2021. Nošenje maske je naša nova realnost, naj bo vseeno udobna, nežna in prijetna. Maske imajo ''perfect fit'' saj imajo nastavljivo elastiko in mehko žičko. Narejene so v Sloveniji iz 4ih plasti 100% 22 momme svile in pakirani z 2x PM2,5 filtrom za dodatno zaščito. *Maske najdeš TUKAJ. *O učinkovitosti mask si lahko prebreš TUKAJ. * Omenjeno v podcastu: Mikelo Veren najdeš na instagramu @mikelaveren in na spletni strani http://inmind.si/. *Za vse poslušalke Inbed podcasta nudi 10EUR popusta za psihološka svetovanja, tako namesto 50 EUR plačate 40 EUR za termin.* Ne pustimo, da tesnoba narekuje naš vsakdan. Odgovornost za dobro počutje nosimo sami. Kdaj zmoremo narediti spremembo čisto sami, kdaj pa rabimo pomoč. Omenjene dihalne vaje za takojšno pomoč pri tesnobi: https://www.youtube.com/watch?v=tybOi4hjZFQ&t=266s Zelo bom vesela tvojega odziva, kako si doživljaja epizodo in pa tvojih predlogov za prihodnje epizode. Najdeš me na instagramu @inbedwithklara in @inbed_podcast za dodatno motivacijo, da se zavzameš za svojo življenje!

①IOC president Bach sends out invitation as Beijing 2022 marks one-year countdown ②Expectations running high on Beijing 2022 Winter Olympics ③Insiders: what contributes to Beijing's record-low PM2.5 density ④WHO says Africa to receive 90 mln COVID-19 vaccine doses in February ⑤UK trial to test combining Pfizer and AstraZeneca vaccines in two-shot regimen

戴口罩已經是全民日常，但市售口罩的防護效果恐怕不夠，還隱藏有害物質。消基會抽驗雙北市口罩發現，20件樣品中，有3件口罩的外層含重金屬鉛。鉛對於發育中的兒童危害最大，恐怕會影響中樞神經發育。雖然驗出來的殘留量在國內沒有超標，但已經超過國際標準，尤其口罩和嘴巴接觸的機會大，制定標準上應該依照年齡分級。 在口罩的防護效果上，消基會測試口罩的PM2.5過濾效率，換算成「次微米粒子防護效率」，結果發現，有6件口罩沒有達到80％以上，也就是說，以病毒的分子大小來看，這些口罩的遮擋效果還不夠。 另外，20件口罩中高達9成，含有揮發性有機物，長時間吸入可能會有頭暈、噁心、呼吸困難及刺激的現象。防疫期間，大家幾乎長時間戴著口罩，可能吸入各種揮發性有機物。 我們該怎麼自保呢？消基會建議 4個重點： 選擇標示完整的商品。 如果對於染料的安全有疑慮，建議優先選擇白、藍、綠等內層是無色的產品。 使用之後要廢棄的口罩屬於一般垃圾，要確實分類丟棄，才不會變成環境負擔。 新買的口罩如果是用塑膠袋密封的，可以先拿出幾片，在空氣中擺一陣子，讓揮發性有機物散掉，並且儘快用完。

※ 本文章发布于订阅号：百车全说，订阅号阅读更加方便，欢迎关注前几天，奥迪给自己旗下的全新A3开了一个发布会，主持人朱广权AKA“押韵王者”在台上也是奋力押韵，比如“颜值想要高，跑车元素不能少，出风口看齐兰博超跑，挡把形似911”……要我说，发布会实在有些枯燥，但唐艺昕的颜值确实挺高。我在看发布会的时候，发现有不少弹幕都是粉丝在刷屏，这不禁让我想到，我一个在奥迪4S店做销售的朋友跟我说的一件事情，也是跟粉丝有关。今年元旦的时候，一个年纪不大的小姑娘带着家里人一起来4S店，小姑娘看起来也就二十出头，朋友以为是陪家里人来买车，没想到询问下来，得知是给即将大学毕业的女儿买台车。小姑娘在展厅里看了一圈，问我朋友店里有没有王一博限量版的A3，我这个销售朋友就告诉他，限量版的只能在网上买，而且时间已经过了。小姑娘说自己在网上没抢到，觉得有点遗憾，想着能不能在线下4S店碰碰运气，销售自然是表示无能为力。不过，小姑娘也表示理解，然后订了一台2021款的两厢时尚运动型，不仅选择了和限量版类似的哥特兰绿色，还选配了5850元的视觉氛围灯升级装备包，整台车一共优惠了10个点，落地在24万左右，这也是目前的正常行情，小姑娘很满意，家里人也觉得可以，就很爽快把车定了，最近这个销售朋友也是刚刚把车交给客户。（王一博限量版）可能有人会疑惑，奥迪才开完发布会，怎么都交车了呢？其实，在去年的11月份，各个经销商就已经开始了全新A3的预售，那时候我们这里4S店的销售，一般都会让客户把购车预算提升至23万左右，后来两厢版本的试驾车和展车陆续到店，很多销售手里的订单都接的是两厢版，三厢版本的展车和试驾车最近才陆续到店，目前也是陆陆续续的开始有订单，同时2020款的A3也有现车在卖，价格也是很给力，基本上低配车型15万左右就可以拿下。我问这个销售朋友，冲着王一博来看车的人多吗？销售朋友跟我说，有一部分小姑娘来店里看奥迪A3是因为王一博，据说王一博限量版在二级市场里最高炒到了70万元一台的天价……我的天呐，一台1.4T的奥迪A3卖70万，这车简直就是一台比EVO 9还牛X的理财神器，不得不佩服粉丝们的购买力。而那些买不到王一博限量版的小姑娘，很多都会选择和限量版同款的黑色或者绿色，然后回去自己再照着限量版美化一下，现在某宝已经有1：1的车辆贴纸，我看了一下价格也不贵，基本上就在几十块钱，估计过不了多久，同款包围和轮毂也会面世。那么，借着今天这个机会，我们也来好好聊一下，全新上市的奥迪A3到底值不值得去买？全新奥迪A3到底怎么样首先，2021款的奥迪A3依旧和以前一样，分成了两厢版和三厢版两个车型，其中两厢版售价20.31-24.32万元，三厢版售价20.96-24.97万元，比之前2020款两厢19.32-22.86万、三厢19.92-23.46万的价格高了一些。奥迪A3这车一直很有意思，看起来配置很多，实际上就是在两厢和三厢的前提上，分了“进取”、“时尚”、“豪华”三个配置，然后根据外观、内饰的小差别分成了“致雅型”和“运动型”，所以买A3其实很简单，只要你认准了这个车，剩下来就是看买两厢还是三厢，买低中高哪个配置，另外就是两厢版车型有电动后备箱，但是三厢版却没有，这一点让我有点没看懂。除了价格变高一些之外，全新奥迪A3三厢版的尺寸变成了4554*1820*1460mm，轴距2680mm，轴距相比老款车型加长51mm，这也是A3国产以来首次进行加长，理论上后排乘坐空间会有所改善，但就我实际体验下来的感觉，三厢版本的车内空间相比于老款车型没有明显的改善，整个车内的空间感受很一般，而两厢版的尺寸分别为4343*1815*1458mm，轴距2630mm，和海外版车型保持一致。虽然车子的尺寸比以前变大了一些，但是这一代A3的颜值确实能打，整体外观设计有点奥迪RS的味道，但是三厢版本侧裙上的镀铬饰条总让我感觉有些突兀，相比之下两厢版本的车身造型会协调很多，不过这是小问题，觉得镀铬饰条不好看的话，可以连着窗框一起贴个亮黑色的改色膜，一般包工包料也就小几百块钱，但整体质感会提升不少。值得注意的是，这一代车型终于从中配开始就有18寸轮毂了，这样也为很多朋友后期进行车辆优化提供了便利性，毕竟在不改变轮胎的参数的前提下，更换轮毂是完全合法的，觉得原厂轮毂不好看，直接同尺寸换掉就完事儿了，在这儿也是给大家一个轮毂数据参考：18*8J、ET在32~38之间都可以（ET32基本齐平叶子板）、PCD5*112、CB57.1（如果买的轮毂CB＞57.1，买套变径圈就可以了）。除了外观上的升级之外，内饰上也是进行了升级，不仅全系标配了10.1寸的中控，而且还有12.3英寸全液晶仪表（豪华版标配，其他配置选配）和真皮+Alcantara（豪华运动型标配，豪华致雅型是仿皮）可以选择安全，除此之外就是从中配开始标配的车道偏离预警、全系标配的主动刹车系统，以及可以选装的14喇叭B&O音响（6000元）、后排侧气囊（1500元）、不带车道保持的并线辅助（7000元）、倒车车侧预警系统（7000元）、自动泊车入位（4000元）、感应后备箱（2000元）、全车无钥匙进入（2000元）、方向盘加热（1000元）、自动防炫目后视镜（1500元）、HUD抬头显示（8500元）……而且还有选配套装能进行购买，除了最低配车型不能选配18寸轮毂之外，其他基本上都是可选的，甚至可以说只要钱到位，随你挑选配。并且，由于目前全新A3的车源很紧俏，有不少地方是来一台卖一台，所以经销商也不会因为库存问题，来调整优惠幅度，想选配就等一等车，想立马开走就买现车，但是等后期车源逐步稳定，甚至出现一定库存积压之后，经销商势必会针对店内现车和选配车辆，给出不同的优惠力度。但是，就目前上市的全新A3而言，这台车总给我一种“新瓶装旧酒”的感觉，这一点同理于我之前说过的高尔夫8代，只不过由于起售价比高尔夫8代高不少，所以在配置上会比高尔夫8代更多一些。首先，这台车和在售的高尔夫8代一样，发动机依旧是过去那套150马力、250牛米的大众祖传1.4T EA211发动机，变速箱也是上一代A3用的7速S-Tronic双离合变速箱，百公里加速9.1秒的成绩也不算亮眼。其次，在海外上市的奥迪A3，不仅有2.0T四驱版本，而且还可以选装19寸轮毂、能降低10mm车身高度的自适应悬架系统、能降低15mm车身高度的运动悬架、差别：国外有四驱，也有自适应悬架软硬，运动状态下降10mm……除了这些“小钢炮”属性的配置之外，海外版的A3还有支持闭缸的1.5T EVO发动机+48V轻混系统。所以，我就很疑惑，奥迪（包括大众）为什么不直接给新车用上这套1.5T EVO发动机+48V轻混，如果之前说这套动力系统还有待市场检验，但是要知道这套动力早在2016年的时候就已经发布，并且陆陆续续在海外装车使用，如果说国内生产这颗发动机需要引进、调试新的生产线，那我就好奇了，从2016年到现在2021年，足足4年多接近5年的时间，怎么就不够他们去弄呢？还是说老款发动机库存量太大，需要新车型来进一步消化库存？（大众祖传1.4T）反观2020年奥迪在华的全年销量达到了726288台，虽然说输给了宝马的77.7万辆和奔驰的77.4万辆，但是奥迪全年销量同比增长了5.4%，并且中国市场为奥迪贡献了超过三分之一的全球销量，在全球低迷的2020年第二季度，中国市场更是以189182辆的成绩占据奥迪全球一半以上销量，而大众集团2020在华销量超过了385万量……换言之，中国市场已经成为一块无法舍弃的大蛋糕。所以，我是不是可以理解为，他们认为即便给新车配上一套老掉牙的动力总成，依旧会有足够多的消费者去买单？或者说刻意的进行区别对待呢？依照目前我得到的消息来看，去年12月10日的时候，符合国六b标准的EA211 1.5T EVO发动机项目在一汽大众长春基地启动，但是这并不代表在长春基地生产，根据小道消息，这套1.5T的发动机在一汽大众的成都工厂已经开始进行小批量生产试装，后期也会由成都工厂进行全面制造，并且整个大众在今年有希望推出1.5T版本的车型（包括高尔夫、A3、速腾、迈腾、宝来、探岳、探歌等等），但是在1.5T版本车型推出的同时，1.4T版本的车型会继续销售，我们是不是可以推测一下，届时1.4T的奥迪A3能迎来一波价格跳水？（1.5T EVO发动机）A3和它的对手们A3的竞争对手都有谁，答案很明显，无非就是国产的奔驰A级和宝马1系，当时相比于那两台车，奥迪A3可以说是最早进行国产化的车型。第一代A3与我们无缘，第二代A3两厢版是在2010年全进口进入国内，当时售价26.8万~32.8万。但是到了2014年第三代A3面世，这台车不仅开始了国产化，同时还以进口车方式又引入了原装的两厢版车型和三厢版车型，换言之你想买进口就买进口，想买国产就买国产，但当时国产后的A3定价19.99万~29.27万，直接把准入门槛拉低到20万内，要知道那时候宝马1系和奔驰A级都是进口车，奥迪直接通过低价杀入了这片A级车市场。（前三代A3）由于最开始的国产A3只配备了1.4T EA211发动机，所以进口A3为了给国产让路，也就没有再引入1.4T车型，14款进口A3无论两厢、三厢都换成了1.8T第三代EA888发动机，马力从之前第二代的160马力变成了180马力，并解决了原先的烧机油问题，再利用进口版本27.98万~32.43万的指导价，和国产版本形成格错位。到了2015款时，由于1.8T全系车型也国产化了，所以进口A3就引进了搭载1.8T发动机的敞篷版本，同时还新增了搭载第三代EA888 2.0T高功率发动机的两厢和三厢版本，定价上为了避开国产1.8T车型，直接定了一个29.98万~36.98万的天价。可惜，再到17款时，就只剩下极度小众、同时换装了用于取代1.8T发动机的EA888 2.0T低功率发动机（190马力）的敞篷车型在售，这时候其实已经可以看出奥迪想要放弃进口A3了，再往后进口A3就完全停止引进、到此为止了。（第三代A3敞篷版）进口A3中让我印象比较深的是15款挂着“45TFSI”尾标的两厢和三厢版本，第三代EA888 2.0T高功率发动机有220马力、350牛米，三大件和动力输出与当年的高尔夫GTI一样，基本相当于GTI的换壳，但是比高尔夫GTI品牌更强、内饰更香、进口身份，虽然指导价上到29.98万~30.48万，比GTI贵了6万左右，但终端优惠完之后比GTI贵不了太多，可惜当时懂这车的人并不多，很多人看到指导价就被吓走了。至于国产A3反而没什么故事可说。从2014年上市开始就两厢、三厢一起发力，最早的14款全部都是1.4T车型，15款时又加入了1.8T车型作为补充，17款中期改款时，用EA888 2.0T低功率发动机取代了原先的EA888 1.8T发动机，于是1.4T与2.0T低功率车型一起共同销售至这次换代之前。相比之下，宝马在2017年2月宣布国产1系上市，奔驰则是在2018年11月宣布国产A级上市，换言之从2017年宝马1系国产之后开始，A3与1系就进入了价格对杀环节，到了2018年奔驰A级进行国产拉皮加长之后，BBA三家在A级车市场的厮杀正式进入高潮，现在第四代A3的外观、内饰经过全面更新，看样子是准备给这把烧得正旺的“火”再浇一把“油”。那么，现在奥迪A3相比奔驰A级和宝马1系该如何去选？首先，我一直以来都认为A3有一个A级和1系都没有的优势，那就是它同时国产化了两厢和三厢版本，相比之下奔驰A级只国产了三厢版本，并且轴距加长，两厢版本保持进口，国产的三厢1系则是一款特供车，进口的两厢1系在海外已经换代，目前还没有引入国内。奔驰A级与1系两厢之所以没有国产，可能是他们不太看好国内的两厢小车市场，但实际上A3的两厢版本销量并不像很多人想得那么低，这种有牌子、又好开、不太贵的车本身就能吸引一部分客户，并且目前在这个级别、这个价位，市面上能满足此类客群需求的也就A3的两厢版本，要不然就加些钱去买MINI。用A3去和国产A级进行PK，其中国产A级比较主流的选择，是指导价23.28万的A180L运动轿车和指导价26.48万的A200L运动轿车时尚型，一个是优惠后19.8万左右的1.3T低功率车型的高配，另一个是优惠后23万左右的1.3T高功率车型的高配。其中，A180L运动直接对应的应该是A3三厢中配的时尚致雅/运动型，指导价22.98万。但目前A3刚刚换代，终端优惠比较可怜，A3三厢时尚实际裸车价格超过20.5万，比A180L运动贵了大几千块，不过这种情况估计持续不了多久。根据我实际体验下来的结果，在空间上这代A3三厢是输给奔驰A级的，这代A3的三厢版本虽然带“L”了，4554（4548）mm的车长比以前长了90mm左右，2680mm的轴距也比以前长了51mm，但人家A级也经过了加长，并且加长得更加夸张，长宽高4622/1796/1454mm，轴距2789mm，尤其是轴距，一下长出了100mm都不止，所以在乘坐空间上，这代A3三厢还是比不过A级，毕竟国产A级的后排空间比标轴C级还大。在三大件上，两者算是打平，A3全系都是1.4T，150马力、250牛米，匹配7速干式双离合；而A180L运动是1.3T低功率，136马力、200牛米，匹配7速湿式双离合，数据上存在一定差距，但实际两车的破百时间几乎一样，都是9秒左右。主要问题在于A3配备的是很多人都比较害怕的干式双离合，虽然理论上这个变速箱技术比较成熟了，但很多人还是偏向A级上的湿式双离合。不过，A3全系都是多连杆式独立悬挂，而A级除了顶配外都是扭力梁式非独立悬挂，这一点也非常有奔驰特色，同时A3三厢时尚的225/40 R18的胎圈规格也比A级更高，毕竟A级除了顶配之外，全系都是205/55 R17的圈胎数据。在内部配置上，A3三厢时尚其实更加丰富一些，尤其是主动安全和驾驶辅助配置，它比A180L运动多了车道偏离预警、疲劳驾驶提示、倒车影像、全速自适应巡航，而A180L运动只多一个没有任何用的被动行人保护，此外还有自动泊车和自动驻车。在其他常用配置方面，A3三厢时尚比A180L运动多了主驾腰部支撑、主驾电动调节、温度分区控制和车内PM2.5过滤，并且现在A3已经全系标配LED大灯，而A180L运动的大灯还是卤素的。而A180L运动最大的优势，我觉得是那双10.25英寸大联屏，当然A3三厢时尚在这方面也不差，全系起步就是10.25英寸液晶仪表+10.1英寸中控屏幕，只不过视觉效果没有大联屏那么爽。至于A200L运动时尚，指导价超A3三厢顶配的豪华致雅/运动型不少，反倒更像是以后2.0T低功率、也就是“40TFSI”尾标A3的直接对手，但即使是这样，A3三厢豪华在配置上依然不输，甚至在安全和驾驶配置上依然有肉眼可见的优势。其实单论性价比，奔驰A级可以说性价比非常低，但是，奔驰玩的就不是这个，买奔驰A级的人在意的也不是所谓的性价比，当你打开车门之后，一个巨大的双联屏放在那里，高配还有64色氛围灯，再加上车头硕大的三叉星标，就问你看完迷糊不迷糊。除了奔驰A级外，奥迪A3和国产宝马1系相比，只能说打了宝马一个时间差，这也是奥迪常用的招数，在售的小改款A4L就是这么玩的，由于奥迪A3刚刚新车上市，所以宝马1系相比之下就会显得有些“老”，但是老也有老的好处，宝马1系现在价格非常给力，以目前的价格行情来看，国产1系最顶配、指导价24.68万的125i M运动曜夜版，优惠后的裸车价妥妥在20万以内，有的地方甚至能做到18.5万的裸车价，这已经和指导价20.96万的A3三厢最低配进取致雅/运动型优惠后差不多了，人家宝马还是个顶配，而且125i M运动曜夜版用的是7速湿式双离合，也配了后多连杆独立悬架，胎圈规格还达到了225/40 R18，而A3三厢进取还是17寸的圈胎。同时，宝马125i M运动曜夜版配备了代号B48A20C的2.0T发动机，原厂数据就达到了192马力、280牛米，相比之下A3 1.4T发动机的150马力、250牛米就是弟中弟般的存在，这还不算后期的改装空间，奥迪A3想要性能上不输给宝马1系，那得看之后的A3 2.0T版本怎么玩了。但是，宝马1系的内部配置确实比不上A3三厢，仅仅是A3三厢进取上的主动刹车、疲劳驾驶提示、定速巡航、10.25英寸液晶仪表、后排中央扶手、后排杯架、自动空调、后排出风口、温度分区控制、车内PM2.5过滤等等配置，在宝马125i M运动曜夜版上你都看不见，要么就是要选装。同时A3标配的换挡拨片在强调运动的1系上竟然全系都没有，而且宝马125i M运动曜夜版已经是顶配车型了，可是它的是空调还是手动的，所以相比之下，奥迪A3的内饰和配置会比宝马1系更能打，当然，如果你想买1.5T三缸版本的宝马1系，我劝你还是再看看吧。那么，这一代A3的两厢和三厢版本该怎么选，其实这个问题不用我多说，因为两厢有两厢的客群，三厢也有三厢的客群，买两厢版车型的客户，要么是家里已经有别的大车，不会用这台车去承载家庭需求，要么是就单纯的喜欢两厢小车，一米八几开A3的猛男壮汉我也见过，他们就是喜欢这种开小车的感觉；三厢版A3则偏向“务实”一点，既能在一定程度上满足实用性的需求，又有奥迪的品牌加持。在同配置下，奥迪A3的三厢版会比两厢版贵6500块钱，但两厢版会比三厢版多出电动尾门和尾门记忆，所以归根结底还是个人喜好的问题，如果让我在两厢版和三厢版之间进行选择，我还是会选择两厢版车型，毕竟如果你真的追求大空间，又何必来买A3呢？结尾对于这台全新的奥迪A3，也是在团队中进行了一个讨论，聊一聊各自的看法。兔子说，自己之前帮朋友深度优化过一台45TFSI版本的A3，不仅针对各个性能部件进行了强化升级，而且移植了DQ500变速箱、is38涡轮和S3的四驱系统，整台车优化之后不仅性能不输S3，而且两厢的造型比三厢S3更吸睛，现在很多A3 45TFSI车主也都会这么去玩，所以兔子觉得现在的A3已经失去了当年的味道，以前好歹还有个高功率版本可以扮猪吃老虎，即使不做那么深度的优化升级，也是一台合格的小钢炮，而现在即使是旧款2.0T 40TFSI都已经成了猪，更不用说1.4T版本了，所以与其为了四个圈去买一台A3，还不如等一等高尔夫GTI。传垚觉得，奥迪A3这台车不会成为他的菜，他更期待的是S3和RS3，并且特别希望能有两厢版本的车型进入国内，不过真要进入国内了，看看老款奥迪S3和RS3的价格，再看看S3和RS3的性能……他估计到时候又要后悔自己买A45了。在我看来，奥迪A3的目标受众其实很简单，主要就是面对那些希望有一个小车来满足自己日常通勤、购车预算在20万上下但实际手头预算极其充裕的年轻人，他们所追求的就是精致、好开、操控不错、颜值到位，并且能脱离高尔夫这个层次。换言之，厂家其实一开始并没有把那些等降价的客户列入目标受众，只是现在的市场环境使得奥迪不得不通过降价和折扣来保证销量。以我实际体验下来的感觉，全新的奥迪A3在外观和内饰方面确实提升很多，特别能迎合年轻人（尤其是女性客户）的胃口，加上选择王一博作为形象代言人，确实是一个很不错的营销手法，也能促使很多王一博的粉丝们，即使自己没有去买奥迪A3，也会成为“自来水”去推荐身边的人买A3，或者自己以后去买一台奥迪A3，这也是“饭圈文化”的一个缩影。但是，王一博现在光是在微博上的粉丝就已经突破了3700万，他现在的代言费用肯定不会低，这个代言费的成本最后势必会摊到消费者头上。以目前的行情来看，最值得买的版本应该是中配版本，由于选装与否都不会影响优惠幅度，所以可以在中配车型的基础上，选择一些自己需要的配置，比如5850元的视觉氛围灯装备包（30色氛围灯+12.3寸全液晶仪表）、8000元的矩阵式LED大灯包（矩阵灯光范围调节、LED前大灯带灯组、LED组合后尾灯、可变化的灯光功能、大灯清洗装置）……这个价格会比拿车后自己加装原厂件要便宜很多。最后，如果想要入手奥迪A3的朋友，我建议最起码等半年后有大幅度优惠的时候再做计划，如果实在等不及，现在的行情基本就稳定在10个点，过完年之后估计会再多2~3个点，以目前的情况来看，这样的价格会持续一段时间，假如你确实不急着买的话，可以等后期配备1.5T发动机，并且价格和优惠趋于稳定后再入手。*图片源自网络音频图文更新在订阅号： 百车全说每期抽三条留言，每人赠168元的“芥末绿”燃油添加剂一瓶点击订阅，每周三，周六更新会有提醒新听友可以搜索：百车全说2014，百车全说2015，百车全说2016，往期300多个小时的节目可供收听

Bojan Simišić iz Eko straže u novoj epizodi podcasta "Život na srpskom" govori o zagađenju kojem smo svi izloženi, zbog kojeg ljudi umiru u našoj zemlji i povodom kojeg je 10. januara 2021. u Beogradu održan "Protest za bezopasan vazduh". Šta su to PM2.5 čestice? Kako nastaju? Zašto su tako opasne? Šta možemo da učinimo da se zaštitimo? Pomažu li prečišćivači vazduha i maske? Pomaže li protest? Zašto Zeleno brdo nije zeleno? To su samo neka od pitanja na koja nam Simišić daje jasne i jednostavne odgovore. Autorka podcasta je Ana Kalaba.

※ 本文章发布于订阅号：百车全说，订阅号阅读更加方便，欢迎关注前几天，奥迪给自己旗下的全新A3开了一个发布会，主持人朱广权AKA“押韵王者”在台上也是奋力押韵，比如“颜值想要高，跑车元素不能少，出风口看齐兰博超跑，挡把形似911”……要我说，发布会实在有些枯燥，但唐艺昕的颜值确实挺高。我在看发布会的时候，发现有不少弹幕都是粉丝在刷屏，这不禁让我想到，我一个在奥迪4S店做销售的朋友跟我说的一件事情，也是跟粉丝有关。今年元旦的时候，一个年纪不大的小姑娘带着家里人一起来4S店，小姑娘看起来也就二十出头，朋友以为是陪家里人来买车，没想到询问下来，得知是给即将大学毕业的女儿买台车。小姑娘在展厅里看了一圈，问我朋友店里有没有王一博限量版的A3，我这个销售朋友就告诉他，限量版的只能在网上买，而且时间已经过了。小姑娘说自己在网上没抢到，觉得有点遗憾，想着能不能在线下4S店碰碰运气，销售自然是表示无能为力。不过，小姑娘也表示理解，然后订了一台2021款的两厢时尚运动型，不仅选择了和限量版类似的哥特兰绿色，还选配了5850元的视觉氛围灯升级装备包，整台车一共优惠了10个点，落地在24万左右，这也是目前的正常行情，小姑娘很满意，家里人也觉得可以，就很爽快把车定了，最近这个销售朋友也是刚刚把车交给客户。（王一博限量版）可能有人会疑惑，奥迪才开完发布会，怎么都交车了呢？其实，在去年的11月份，各个经销商就已经开始了全新A3的预售，那时候我们这里4S店的销售，一般都会让客户把购车预算提升至23万左右，后来两厢版本的试驾车和展车陆续到店，很多销售手里的订单都接的是两厢版，三厢版本的展车和试驾车最近才陆续到店，目前也是陆陆续续的开始有订单，同时2020款的A3也有现车在卖，价格也是很给力，基本上低配车型15万左右就可以拿下。我问这个销售朋友，冲着王一博来看车的人多吗？销售朋友跟我说，有一部分小姑娘来店里看奥迪A3是因为王一博，据说王一博限量版在二级市场里最高炒到了70万元一台的天价……我的天呐，一台1.4T的奥迪A3卖70万，这车简直就是一台比EVO 9还牛X的理财神器，不得不佩服粉丝们的购买力。而那些买不到王一博限量版的小姑娘，很多都会选择和限量版同款的黑色或者绿色，然后回去自己再照着限量版美化一下，现在某宝已经有1：1的车辆贴纸，我看了一下价格也不贵，基本上就在几十块钱，估计过不了多久，同款包围和轮毂也会面世。那么，借着今天这个机会，我们也来好好聊一下，全新上市的奥迪A3到底值不值得去买？全新奥迪A3到底怎么样首先，2021款的奥迪A3依旧和以前一样，分成了两厢版和三厢版两个车型，其中两厢版售价20.31-24.32万元，三厢版售价20.96-24.97万元，比之前2020款两厢19.32-22.86万、三厢19.92-23.46万的价格高了一些。奥迪A3这车一直很有意思，看起来配置很多，实际上就是在两厢和三厢的前提上，分了“进取”、“时尚”、“豪华”三个配置，然后根据外观、内饰的小差别分成了“致雅型”和“运动型”，所以买A3其实很简单，只要你认准了这个车，剩下来就是看买两厢还是三厢，买低中高哪个配置，另外就是两厢版车型有电动后备箱，但是三厢版却没有，这一点让我有点没看懂。除了价格变高一些之外，全新奥迪A3三厢版的尺寸变成了4554*1820*1460mm，轴距2680mm，轴距相比老款车型加长51mm，这也是A3国产以来首次进行加长，理论上后排乘坐空间会有所改善，但就我实际体验下来的感觉，三厢版本的车内空间相比于老款车型没有明显的改善，整个车内的空间感受很一般，而两厢版的尺寸分别为4343*1815*1458mm，轴距2630mm，和海外版车型保持一致。虽然车子的尺寸比以前变大了一些，但是这一代A3的颜值确实能打，整体外观设计有点奥迪RS的味道，但是三厢版本侧裙上的镀铬饰条总让我感觉有些突兀，相比之下两厢版本的车身造型会协调很多，不过这是小问题，觉得镀铬饰条不好看的话，可以连着窗框一起贴个亮黑色的改色膜，一般包工包料也就小几百块钱，但整体质感会提升不少。值得注意的是，这一代车型终于从中配开始就有18寸轮毂了，这样也为很多朋友后期进行车辆优化提供了便利性，毕竟在不改变轮胎的参数的前提下，更换轮毂是完全合法的，觉得原厂轮毂不好看，直接同尺寸换掉就完事儿了，在这儿也是给大家一个轮毂数据参考：18*8J、ET在32~38之间都可以（ET32基本齐平叶子板）、PCD5*112、CB57.1（如果买的轮毂CB＞57.1，买套变径圈就可以了）。除了外观上的升级之外，内饰上也是进行了升级，不仅全系标配了10.1寸的中控，而且还有12.3英寸全液晶仪表（豪华版标配，其他配置选配）和真皮+Alcantara（豪华运动型标配，豪华致雅型是仿皮）可以选择安全，除此之外就是从中配开始标配的车道偏离预警、全系标配的主动刹车系统，以及可以选装的14喇叭B&O音响（6000元）、后排侧气囊（1500元）、不带车道保持的并线辅助（7000元）、倒车车侧预警系统（7000元）、自动泊车入位（4000元）、感应后备箱（2000元）、全车无钥匙进入（2000元）、方向盘加热（1000元）、自动防炫目后视镜（1500元）、HUD抬头显示（8500元）……而且还有选配套装能进行购买，除了最低配车型不能选配18寸轮毂之外，其他基本上都是可选的，甚至可以说只要钱到位，随你挑选配。并且，由于目前全新A3的车源很紧俏，有不少地方是来一台卖一台，所以经销商也不会因为库存问题，来调整优惠幅度，想选配就等一等车，想立马开走就买现车，但是等后期车源逐步稳定，甚至出现一定库存积压之后，经销商势必会针对店内现车和选配车辆，给出不同的优惠力度。但是，就目前上市的全新A3而言，这台车总给我一种“新瓶装旧酒”的感觉，这一点同理于我之前说过的高尔夫8代，只不过由于起售价比高尔夫8代高不少，所以在配置上会比高尔夫8代更多一些。首先，这台车和在售的高尔夫8代一样，发动机依旧是过去那套150马力、250牛米的大众祖传1.4T EA211发动机，变速箱也是上一代A3用的7速S-Tronic双离合变速箱，百公里加速9.1秒的成绩也不算亮眼。其次，在海外上市的奥迪A3，不仅有2.0T四驱版本，而且还可以选装19寸轮毂、能降低10mm车身高度的自适应悬架系统、能降低15mm车身高度的运动悬架、差别：国外有四驱，也有自适应悬架软硬，运动状态下降10mm……除了这些“小钢炮”属性的配置之外，海外版的A3还有支持闭缸的1.5T EVO发动机+48V轻混系统。所以，我就很疑惑，奥迪（包括大众）为什么不直接给新车用上这套1.5T EVO发动机+48V轻混，如果之前说这套动力系统还有待市场检验，但是要知道这套动力早在2016年的时候就已经发布，并且陆陆续续在海外装车使用，如果说国内生产这颗发动机需要引进、调试新的生产线，那我就好奇了，从2016年到现在2021年，足足4年多接近5年的时间，怎么就不够他们去弄呢？还是说老款发动机库存量太大，需要新车型来进一步消化库存？（大众祖传1.4T）反观2020年奥迪在华的全年销量达到了726288台，虽然说输给了宝马的77.7万辆和奔驰的77.4万辆，但是奥迪全年销量同比增长了5.4%，并且中国市场为奥迪贡献了超过三分之一的全球销量，在全球低迷的2020年第二季度，中国市场更是以189182辆的成绩占据奥迪全球一半以上销量，而大众集团2020在华销量超过了385万量……换言之，中国市场已经成为一块无法舍弃的大蛋糕。所以，我是不是可以理解为，他们认为即便给新车配上一套老掉牙的动力总成，依旧会有足够多的消费者去买单？或者说刻意的进行区别对待呢？依照目前我得到的消息来看，去年12月10日的时候，符合国六b标准的EA211 1.5T EVO发动机项目在一汽大众长春基地启动，但是这并不代表在长春基地生产，根据小道消息，这套1.5T的发动机在一汽大众的成都工厂已经开始进行小批量生产试装，后期也会由成都工厂进行全面制造，并且整个大众在今年有希望推出1.5T版本的车型（包括高尔夫、A3、速腾、迈腾、宝来、探岳、探歌等等），但是在1.5T版本车型推出的同时，1.4T版本的车型会继续销售，我们是不是可以推测一下，届时1.4T的奥迪A3能迎来一波价格跳水？（1.5T EVO发动机）A3和它的对手们A3的竞争对手都有谁，答案很明显，无非就是国产的奔驰A级和宝马1系，当时相比于那两台车，奥迪A3可以说是最早进行国产化的车型。第一代A3与我们无缘，第二代A3两厢版是在2010年全进口进入国内，当时售价26.8万~32.8万。但是到了2014年第三代A3面世，这台车不仅开始了国产化，同时还以进口车方式又引入了原装的两厢版车型和三厢版车型，换言之你想买进口就买进口，想买国产就买国产，但当时国产后的A3定价19.99万~29.27万，直接把准入门槛拉低到20万内，要知道那时候宝马1系和奔驰A级都是进口车，奥迪直接通过低价杀入了这片A级车市场。（前三代A3）由于最开始的国产A3只配备了1.4T EA211发动机，所以进口A3为了给国产让路，也就没有再引入1.4T车型，14款进口A3无论两厢、三厢都换成了1.8T第三代EA888发动机，马力从之前第二代的160马力变成了180马力，并解决了原先的烧机油问题，再利用进口版本27.98万~32.43万的指导价，和国产版本形成格错位。到了2015款时，由于1.8T全系车型也国产化了，所以进口A3就引进了搭载1.8T发动机的敞篷版本，同时还新增了搭载第三代EA888 2.0T高功率发动机的两厢和三厢版本，定价上为了避开国产1.8T车型，直接定了一个29.98万~36.98万的天价。可惜，再到17款时，就只剩下极度小众、同时换装了用于取代1.8T发动机的EA888 2.0T低功率发动机（190马力）的敞篷车型在售，这时候其实已经可以看出奥迪想要放弃进口A3了，再往后进口A3就完全停止引进、到此为止了。（第三代A3敞篷版）进口A3中让我印象比较深的是15款挂着“45TFSI”尾标的两厢和三厢版本，第三代EA888 2.0T高功率发动机有220马力、350牛米，三大件和动力输出与当年的高尔夫GTI一样，基本相当于GTI的换壳，但是比高尔夫GTI品牌更强、内饰更香、进口身份，虽然指导价上到29.98万~30.48万，比GTI贵了6万左右，但终端优惠完之后比GTI贵不了太多，可惜当时懂这车的人并不多，很多人看到指导价就被吓走了。至于国产A3反而没什么故事可说。从2014年上市开始就两厢、三厢一起发力，最早的14款全部都是1.4T车型，15款时又加入了1.8T车型作为补充，17款中期改款时，用EA888 2.0T低功率发动机取代了原先的EA888 1.8T发动机，于是1.4T与2.0T低功率车型一起共同销售至这次换代之前。相比之下，宝马在2017年2月宣布国产1系上市，奔驰则是在2018年11月宣布国产A级上市，换言之从2017年宝马1系国产之后开始，A3与1系就进入了价格对杀环节，到了2018年奔驰A级进行国产拉皮加长之后，BBA三家在A级车市场的厮杀正式进入高潮，现在第四代A3的外观、内饰经过全面更新，看样子是准备给这把烧得正旺的“火”再浇一把“油”。那么，现在奥迪A3相比奔驰A级和宝马1系该如何去选？首先，我一直以来都认为A3有一个A级和1系都没有的优势，那就是它同时国产化了两厢和三厢版本，相比之下奔驰A级只国产了三厢版本，并且轴距加长，两厢版本保持进口，国产的三厢1系则是一款特供车，进口的两厢1系在海外已经换代，目前还没有引入国内。奔驰A级与1系两厢之所以没有国产，可能是他们不太看好国内的两厢小车市场，但实际上A3的两厢版本销量并不像很多人想得那么低，这种有牌子、又好开、不太贵的车本身就能吸引一部分客户，并且目前在这个级别、这个价位，市面上能满足此类客群需求的也就A3的两厢版本，要不然就加些钱去买MINI。用A3去和国产A级进行PK，其中国产A级比较主流的选择，是指导价23.28万的A180L运动轿车和指导价26.48万的A200L运动轿车时尚型，一个是优惠后19.8万左右的1.3T低功率车型的高配，另一个是优惠后23万左右的1.3T高功率车型的高配。其中，A180L运动直接对应的应该是A3三厢中配的时尚致雅/运动型，指导价22.98万。但目前A3刚刚换代，终端优惠比较可怜，A3三厢时尚实际裸车价格超过20.5万，比A180L运动贵了大几千块，不过这种情况估计持续不了多久。根据我实际体验下来的结果，在空间上这代A3三厢是输给奔驰A级的，这代A3的三厢版本虽然带“L”了，4554（4548）mm的车长比以前长了90mm左右，2680mm的轴距也比以前长了51mm，但人家A级也经过了加长，并且加长得更加夸张，长宽高4622/1796/1454mm，轴距2789mm，尤其是轴距，一下长出了100mm都不止，所以在乘坐空间上，这代A3三厢还是比不过A级，毕竟国产A级的后排空间比标轴C级还大。在三大件上，两者算是打平，A3全系都是1.4T，150马力、250牛米，匹配7速干式双离合；而A180L运动是1.3T低功率，136马力、200牛米，匹配7速湿式双离合，数据上存在一定差距，但实际两车的破百时间几乎一样，都是9秒左右。主要问题在于A3配备的是很多人都比较害怕的干式双离合，虽然理论上这个变速箱技术比较成熟了，但很多人还是偏向A级上的湿式双离合。不过，A3全系都是多连杆式独立悬挂，而A级除了顶配外都是扭力梁式非独立悬挂，这一点也非常有奔驰特色，同时A3三厢时尚的225/40 R18的胎圈规格也比A级更高，毕竟A级除了顶配之外，全系都是205/55 R17的圈胎数据。在内部配置上，A3三厢时尚其实更加丰富一些，尤其是主动安全和驾驶辅助配置，它比A180L运动多了车道偏离预警、疲劳驾驶提示、倒车影像、全速自适应巡航，而A180L运动只多一个没有任何用的被动行人保护，此外还有自动泊车和自动驻车。在其他常用配置方面，A3三厢时尚比A180L运动多了主驾腰部支撑、主驾电动调节、温度分区控制和车内PM2.5过滤，并且现在A3已经全系标配LED大灯，而A180L运动的大灯还是卤素的。而A180L运动最大的优势，我觉得是那双10.25英寸大联屏，当然A3三厢时尚在这方面也不差，全系起步就是10.25英寸液晶仪表+10.1英寸中控屏幕，只不过视觉效果没有大联屏那么爽。至于A200L运动时尚，指导价超A3三厢顶配的豪华致雅/运动型不少，反倒更像是以后2.0T低功率、也就是“40TFSI”尾标A3的直接对手，但即使是这样，A3三厢豪华在配置上依然不输，甚至在安全和驾驶配置上依然有肉眼可见的优势。其实单论性价比，奔驰A级可以说性价比非常低，但是，奔驰玩的就不是这个，买奔驰A级的人在意的也不是所谓的性价比，当你打开车门之后，一个巨大的双联屏放在那里，高配还有64色氛围灯，再加上车头硕大的三叉星标，就问你看完迷糊不迷糊。除了奔驰A级外，奥迪A3和国产宝马1系相比，只能说打了宝马一个时间差，这也是奥迪常用的招数，在售的小改款A4L就是这么玩的，由于奥迪A3刚刚新车上市，所以宝马1系相比之下就会显得有些“老”，但是老也有老的好处，宝马1系现在价格非常给力，以目前的价格行情来看，国产1系最顶配、指导价24.68万的125i M运动曜夜版，优惠后的裸车价妥妥在20万以内，有的地方甚至能做到18.5万的裸车价，这已经和指导价20.96万的A3三厢最低配进取致雅/运动型优惠后差不多了，人家宝马还是个顶配，而且125i M运动曜夜版用的是7速湿式双离合，也配了后多连杆独立悬架，胎圈规格还达到了225/40 R18，而A3三厢进取还是17寸的圈胎。同时，宝马125i M运动曜夜版配备了代号B48A20C的2.0T发动机，原厂数据就达到了192马力、280牛米，相比之下A3 1.4T发动机的150马力、250牛米就是弟中弟般的存在，这还不算后期的改装空间，奥迪A3想要性能上不输给宝马1系，那得看之后的A3 2.0T版本怎么玩了。但是，宝马1系的内部配置确实比不上A3三厢，仅仅是A3三厢进取上的主动刹车、疲劳驾驶提示、定速巡航、10.25英寸液晶仪表、后排中央扶手、后排杯架、自动空调、后排出风口、温度分区控制、车内PM2.5过滤等等配置，在宝马125i M运动曜夜版上你都看不见，要么就是要选装。同时A3标配的换挡拨片在强调运动的1系上竟然全系都没有，而且宝马125i M运动曜夜版已经是顶配车型了，可是它的是空调还是手动的，所以相比之下，奥迪A3的内饰和配置会比宝马1系更能打，当然，如果你想买1.5T三缸版本的宝马1系，我劝你还是再看看吧。那么，这一代A3的两厢和三厢版本该怎么选，其实这个问题不用我多说，因为两厢有两厢的客群，三厢也有三厢的客群，买两厢版车型的客户，要么是家里已经有别的大车，不会用这台车去承载家庭需求，要么是就单纯的喜欢两厢小车，一米八几开A3的猛男壮汉我也见过，他们就是喜欢这种开小车的感觉；三厢版A3则偏向“务实”一点，既能在一定程度上满足实用性的需求，又有奥迪的品牌加持。在同配置下，奥迪A3的三厢版会比两厢版贵6500块钱，但两厢版会比三厢版多出电动尾门和尾门记忆，所以归根结底还是个人喜好的问题，如果让我在两厢版和三厢版之间进行选择，我还是会选择两厢版车型，毕竟如果你真的追求大空间，又何必来买A3呢？结尾对于这台全新的奥迪A3，也是在团队中进行了一个讨论，聊一聊各自的看法。兔子说，自己之前帮朋友深度优化过一台45TFSI版本的A3，不仅针对各个性能部件进行了强化升级，而且移植了DQ500变速箱、is38涡轮和S3的四驱系统，整台车优化之后不仅性能不输S3，而且两厢的造型比三厢S3更吸睛，现在很多A3 45TFSI车主也都会这么去玩，所以兔子觉得现在的A3已经失去了当年的味道，以前好歹还有个高功率版本可以扮猪吃老虎，即使不做那么深度的优化升级，也是一台合格的小钢炮，而现在即使是旧款2.0T 40TFSI都已经成了猪，更不用说1.4T版本了，所以与其为了四个圈去买一台A3，还不如等一等高尔夫GTI。传垚觉得，奥迪A3这台车不会成为他的菜，他更期待的是S3和RS3，并且特别希望能有两厢版本的车型进入国内，不过真要进入国内了，看看老款奥迪S3和RS3的价格，再看看S3和RS3的性能……他估计到时候又要后悔自己买A45了。在我看来，奥迪A3的目标受众其实很简单，主要就是面对那些希望有一个小车来满足自己日常通勤、购车预算在20万上下但实际手头预算极其充裕的年轻人，他们所追求的就是精致、好开、操控不错、颜值到位，并且能脱离高尔夫这个层次。换言之，厂家其实一开始并没有把那些等降价的客户列入目标受众，只是现在的市场环境使得奥迪不得不通过降价和折扣来保证销量。以我实际体验下来的感觉，全新的奥迪A3在外观和内饰方面确实提升很多，特别能迎合年轻人（尤其是女性客户）的胃口，加上选择王一博作为形象代言人，确实是一个很不错的营销手法，也能促使很多王一博的粉丝们，即使自己没有去买奥迪A3，也会成为“自来水”去推荐身边的人买A3，或者自己以后去买一台奥迪A3，这也是“饭圈文化”的一个缩影。但是，王一博现在光是在微博上的粉丝就已经突破了3700万，他现在的代言费用肯定不会低，这个代言费的成本最后势必会摊到消费者头上。以目前的行情来看，最值得买的版本应该是中配版本，由于选装与否都不会影响优惠幅度，所以可以在中配车型的基础上，选择一些自己需要的配置，比如5850元的视觉氛围灯装备包（30色氛围灯+12.3寸全液晶仪表）、8000元的矩阵式LED大灯包（矩阵灯光范围调节、LED前大灯带灯组、LED组合后尾灯、可变化的灯光功能、大灯清洗装置）……这个价格会比拿车后自己加装原厂件要便宜很多。最后，如果想要入手奥迪A3的朋友，我建议最起码等半年后有大幅度优惠的时候再做计划，如果实在等不及，现在的行情基本就稳定在10个点，过完年之后估计会再多2~3个点，以目前的情况来看，这样的价格会持续一段时间，假如你确实不急着买的话，可以等后期配备1.5T发动机，并且价格和优惠趋于稳定后再入手。*图片源自网络音频图文更新在订阅号： 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這個地球，不是人類的。人類只是地球上的生物霸權者。只是我們時常錯覺，墾伐，叫做墾荒：宰殺，稱之打獵⋯⋯我們把地球生命一樣古老的礦物，稱之為鑽石，比喻為永恆的愛情，在富裕的社會，互許終身，在產礦的國家，為此殺戮。 2020年，因為COVID-19還有某些國家人類的反省，地球上其他的主人，躣上歷史，奪回了部分「執政權」。 2020年起，更多好萊烏明星決定接受一樣閃亮、由科技製造的「未來鑽石」。 * 三隻小企鵝串門藝術博物館 在疫情博物館封鎖期間，美國堪薩斯城動物園做了一件可愛的事：工作人員帶著園內的三隻洪堡企鵝，至藝術博物館，參觀串門，觀賞人類的藝術，自己也成為藝術的一部分。 「它們似乎對卡拉瓦喬要比莫奈的作品更感興趣一點。」藝術博物館館長這麼說。 * 巴塞隆納歌劇院為 2,292 株植物演奏 因為疫情，所有音樂會皆取消了。2020 年中，巴塞隆納歌劇院重新開幕，表演觀眾席完全留給了植物。 全場座無虛席。 各類植物穿插其中，靜靜傾聽人類演奏樂章。 表演結束後，劇院將植物們送給了為疫情站在前缐冒險的巴塞隆納醫護人員，感謝他們在如此困難的一年中，保護人們的生命。 * 野山羊們成功佔領了一座人類城鎮 因為疫情居家隔離封鎖，城鎮平常熙攘的街道四下無人，2020年3 月，一群野山羊佔領了一座英國威爾斯的小鎮。 它們攀爬著石柵欄，啃著樹籬，在（因為疫情）空無一人的街道上閒逛，土地還給了牠們：至少這一刻。 這些超過 100 隻可愛的克什米爾山羊，過去通常在北威爾斯的山上漫步，也許是奇特的安靜吸引了它們，山羊們確信這是入侵城鎮，拿回「政權」的好時機。 * 守喪 17 天的虎鯨媽媽迎來新的生命 2018 年一隻虎鯨媽媽 Tahlequah，她的孩子不幸夭折而亡，媽媽不離不棄，以頭頂推動的方式帶著死去的小虎鯨在身邊長達 17 天之久，這是人類科學家記錄最長的虎鯨「守喪」的時間記錄。 2020年讓人欣慰的好消息是，Tahlequah 再次誕生一個健康的小虎鯨，觀察人員監聽到它們族群內三組虎鯨聚在一塊，發出大量的共鳴，在喜悅地慶賀新生命降臨世界。他們不需要保持距離，以保障安全。 * 「最孤獨的大象」KAVAAN結束了 35 年監禁生涯 大象 Kavaan 還是小小象的時候，被當成外交政治禮物被送到了巴基斯坦，後來的 35 年一直被監禁在臭名昭著的伊斯蘭堡馬格哈扎動物園，受盡非人道對待。 痛苦的監禁生活中，Kavaan 曾短暫地擁有過一名同伴，但它很快因過度訓練，受傷染上白血病身亡了。 Kavaan 自此脾氣越來越古怪，帶著一身的新舊傷痕，面壁發呆、莫名點頭不止。 2020年國際動物保護人士經由長時間的努力，被稱為「最孤獨大象」的 Kavaan 終於被解救出來了！送往柬埔寨野生動物園區度過餘生（該組織也花了三個月時間籌備這趟 10 小時的旅程），在 25,000 英尺的保護區，與600 多名大象同伴一起生活，園方也透露將介紹三頭母象給它認識。 要知道，成功把 Kaavan 轉移到柬埔寨不僅需要一個村莊，而且需要國家的交涉。 * 瑞典最後一家燃煤電廠關閉了 人類在不斷為自己追求工業發展帶來地球環境破壞，首當其衝是能源尤其煤炭污染，它排放的二氧化碳及PM2.5，危害到全地球的生態和自然環境，甚至物種的存續，也包括人類的健康。 人類世界勢必要達成往低碳方向前進的共識。 在歐洲，比利時早已率先停止了以燃煤作為能源。 今年 4 月，瑞典最後一家燃煤電廠也終於關閉了。 奧地利也將搭上這班駛向未來的列車，明年關閉所有燃煤電廠。 預計在 2025 年，再有七個歐盟國家，全面禁止燃煤。 --陳文茜-- 著作權聲明： 未經《文茜世界日報》書面同意，不得擅自以下載、轉貼或以他法重製本頻道所有內容，亦不得利用《文茜世界日報》頻道所屬之局部或全部內容用以商業或個人利益，或用於商業性質之分享、連結。 任何商業使用與連結，請事先取得《文茜世界日報》書面同意。 ©文茜世界日報 文茜世界日報YouTube頻道：https://www.youtube.com/c/文茜世界日報 製作中心：sisytimes@gmail.com 合作贊助：ariel@stwa.com.tw

FDA 批准MAPK激酶抑制剂治疗手术无法切除的1型神经纤维瘤BMJ 哮喘发作与空气污染和母亲孕期吸烟有关Nature Metabolism 母亲运动带来的后代的健康获益是通过母乳中的3′-唾液酸乳糖介导的司美替尼（selumetinib）神经纤维瘤是常染色体显性遗传病，分1、2和3型。1型神经纤维瘤最常见，标志性特征是多发的牛奶咖啡斑和相关皮肤神经纤维瘤。没有针对性的总体的治疗，只能对症治疗。50%的1型神经纤维瘤患者合并丛状神经纤维瘤，丛状神经纤维瘤是一种组织学上良性的周围神经鞘肿瘤，常累及多个神经束，造成毁容、运动功能障碍、疼痛、甚至脊髓受压。司美替尼是一种MAPK激酶的抑制剂，在2020年4月，FDA批准了司美替尼用于治疗1型神经纤维瘤。《司美替尼治疗不能手术的丛状神经纤维瘤患儿》New England Journal of Medicine，2020年4月 (1)这项开放标签的2期试验，旨在确定丛状神经纤维瘤患儿服用司美替尼后的临床益处和安全性。50名、平均年龄10.2岁的、不能手术的丛状神经纤维瘤的1型神经纤维瘤病患儿入组，随机接受了司美替尼和安慰剂治疗。最常见的神经纤维瘤相关症状包括毁容（44人）、运动功能障碍（33人）和疼痛（26人）。治疗后70%达到了部分缓解，56%≥1年的持久缓解。1年后，肿瘤疼痛评分平均降低了2分，疼痛对日常功能、总体健康相关生活质量、力量和关节活动范围等多项功能结局也观察到了有临床意义的改善。其中5人因副作用停药；6人疾病发展。最常见的毒性作用为恶心、呕吐或腹泻、无症状的肌酸磷酸激酶水平升高、痤疮样皮疹及甲沟炎。结论：对于手术无法切除的丛状神经纤维瘤患儿，司美替尼产生了持久的缩小肿瘤作用。儿童哮喘哮喘（asthma）是一种异质性疾病，特点是慢性气道炎症。12岁以下儿童哮喘是最常见的儿童期慢性疾病，约80%的患儿在5岁以前出现症状，咳嗽、哮鸣、呼吸急促、胸闷胸痛是常见的症状。最常见的诱发因素包括病毒性上呼吸道感染（合胞病毒、流感病毒、鼻病毒）、运动、天气、二手烟和变应原（如尘螨、宠物毛发、花粉、霉菌）。《病例队列研究：空气污染和家庭相关因素与儿童哮喘发作和持续性喘息的关系》BMJ，2020年8月(2)研究目的探讨儿童哮喘和持续性喘息发病的危险因素（空气污染和家庭相关因素）。这项全国病例对照研究中随访了1-15岁儿童儿童哮喘发病率升高，与父母患有哮喘（风险比 2.29）、母亲在怀孕期间吸烟（风险比 1.20）相关。儿童哮喘发病率低，与父母受教育程度高（风险比0.72）和父母收入高（风险比 0.85）相关。空气污染物PM2.5和PM10与哮喘的风险增加和持续喘息相关。结论：暴露于空气污染中的儿童更容易患哮喘和持续性喘息，哮喘与父母哮喘病史、父母教育程度和母亲在怀孕期间吸烟有关。《观察性研究：母亲在怀孕期间吸烟影响子女成年后哮喘发作》European Respiratory Journal 2020年7月 (3)研究的目的是确定产前哮喘和成人哮喘发病之间的关系。研究纳入5200名、1966年芬兰北部出生的、31岁前未诊断为哮喘的人群。研究发现孕妇妊娠最后3个月吸烟，其后代31岁至46岁之间哮喘累积发病率（男性为5.1%，女性为8.8%），尤其是与无哮喘病史（风险比9.63）或咳嗽喘息病史（风险比3.21）的后代中有显著相关性。同时在妊娠期吸烟与31岁时子代的用力呼气量（FEV1）/用力肺活量（FVC）比率之间有发现了显著的相关性，在在RUNX1单倍型rs11702779-AA的后代中成年期患哮喘的风险比为5.53。结论：怀孕期间吸烟与后代成年后哮喘累积发病率有关。《观察性研究：空气污染和从出生到成年的哮喘发展》European Respiratory Journal 2020年7月 (4)空气污染对青春期至成年期哮喘发展的影响尚不清楚，研究纳入了3687个参与者，评估空气污染和哮喘发生的年龄的相关关系。研究20岁之前哮喘的发病率，与出生地空气污染物的比例增加相关（接触PM10的风险比为1.09，接触NO2的风险比为1.20）。对近期家庭居住地的空气污染进行分析后，得到了类似的结果。结论：早年暴露在空气污染中，特别是来自机动交通的污染，与儿童、青春期到成年早期罹患哮喘的风险增加有关。《哮喘患儿卧室颗粒物过滤与气道病理生理变化的关系》JAMA Pediatrics，2020年8月 (5)细颗粒物PM2.5是一种普遍存在的空气污染物，可沉积在小气道中，对哮喘起着至关重要的作用。来自杜克大学与北京上海的研究人员合作，研究PM2.5过滤装置的使用是否能改善哮喘患儿的小气道生理学和呼吸系统炎症。研究人员在患儿的卧室里随机安装了真实的过滤设备和假的过滤设备，试验前有2周的洗脱期，研究是在臭氧含量低的季节在中国上海的郊区进行的。研究纳入轻中度哮喘的、共43个、5-13岁的儿童参加了研究。室外PM2.5浓度中度升高（28.6-69.8μg/m3)；经过滤的卧室PM2.5浓度比不经过滤降低63.4%。过滤的卧室空气能显著改善气道力学，总气道阻力下降24.4%，减少小气道阻力43.5%，呼气流量峰值也显著改善。这些改善与卧室PM2.5的减少显著相关。总体的小气道功能改善均没有统计学意义，但在不伴有嗜酸性气道炎症的参与者中改善显著（13.2%）。结论：室内PM2.5过滤可以通过改善气道力学和功能，减少炎症，改善哮喘患者肺部的气体流动。《VDKA研究：补充维生素D3对低维生素D和哮喘患儿哮喘加重的影响》JAMA，2020年8月 (6)研究的目的探讨维生素D3的补充是否能改善儿童哮喘和低维生素D水平严重恶化的时间。这项随机、双盲、安慰剂对照临床试验，纳入6-16岁的、哮喘严重发作高危儿童共192人，平均年龄9.8岁，女孩40%维生素D3组的37.5%和安慰剂组的34.4%出现≥1次严重恶化。补充维生素D3并没有显著改善哮喘严重恶化的时间，没有显著改善病毒诱导哮喘严重加重的时间，没有显著改善糖皮质激素剂量减量的患者比例，也没有显著减少糖皮质激素的累积剂量。两组严重不良事件相似。结论：该研究不支持在持续性哮喘和低维生素D水平的儿童维生素D3来预防哮喘加重。《前瞻性队列研究：抗生素的使用减少，影响肠道菌群和儿童哮喘发病率》Lancet Respiratory Medicine，2020年7月 (7)在欧洲和北美的一些地区，儿童哮喘的发病率正在下降；有研究提示婴儿期使用抗生素与哮喘风险增加有关。该研究的目的是验证哮喘发病率的降低是否与抗生素处方减少有关，并验证这种变化是由肠道菌群变化介导的。本研究包括基于人群和前瞻性队列分析，使用加拿大不列颠哥伦比亚省（人口400万·700万）每年抗生素处方率和哮喘诊断率的管理数据进行人群分析。2000 - 2014年，1-4岁儿童的哮喘发病率从27·3‰ 下降到20·2‰，降幅26·0%。发病率的降低与

Health Check Ep 48: Innovations in treating lung cancer; decrease risk factors 14:48 mins Synopsis: Fortnightly on Wednesdays, get healthier living tips as The Straits Times chats with expert guests. With November being Lung Cancer Awareness Month, this episode looks at how lung cancer is the no.1 killer among cancers here in Singapore, as is also the case globally. This episode is brought to you by MSD. ST senior health correspondent Joyce Teo hosts Dr Philip Eng, a senior consultant respiratory physician who has his own clinic - the Philip Eng Respiratory & Medical Clinic at the Mount Elizabeth Medical Centre. He has lectured in various countries, trained many doctors in the region, and published numerous articles. They discuss the following: 1. How can non-smokers get lung cancer? For air pollution, what is the WHO (World Health Organisation) standard for PM2.5 levels? (1:42) 2. How has lung cancer treatment evolved to today's gold standard of keyhole surgery, alongside other treatments such as stereotactic radiotherapy, safer chemotherapy drugs, immunotherapy and targeted therapy? (4:00) 4. Advice on how to protect yourself to cover the cost of such treatments: Buy good extra insurance coverage when you're young and fit (7:52) 5. Innovations in lung cancer treatments such as proton beam therapy and costs of such therapies (10:10) 6. Best way to decrease lung cancer risk factors and how smokers should do more effective CT lung scans instead of normal chest X-rays (12:27) Produced by: Joyce Teo (joyceteo@sph.com.sg), Ernest Luis and Penelope Lee Edited by: Adam Azlee Follow Health Check Podcast series fortnightly on Wednesdays and rate us on: Channel: https://str.sg/JWaN Apple Podcasts: https://str.sg/JWRX Spotify: https://str.sg/JWaQ Google Podcasts: https://str.sg/J6Wv  Website: http://str.sg/stpodcasts Feedback to: podcast@sph.com.sg See omnystudio.com/listener for privacy information.

I am a lung doctor who cares for patients in the clinic and ICU when they are sickened from diseases caused or worsened by air pollution. However, air pollution is actually even more damaging to the heart and blood vessels of the body, as my podcast guest Dr. Thomas Muenzel today knows too well. He is a heart doctor who can help intervene to open up arteries on patients who are suffering from blockages that cause heart attacks and other damage. For both of us, having a patient come to need our intervention already indicates that person is very sick, and we would both like to prevent them getting that ill in the first place. Dr. Muenzel has studied how air pollution actually damages the blood vessels in our body and around our heart. COVID19 has been consuming communities around the world, and is currently raging out of control in the United States at the time of this post. Dr. Muenzel and his group have worked to define how many of the deaths from COVID19 may be related to its interaction with air pollution. On the podcast today, we talk about the impact of air pollution on the heart and blood vessels as well as its interaction with COVID19. What to Do: 1- Follow public health guidance on decreasing COVID19 pandemic so we can get through this sooner. 2- Pay attention to the absolute PM2.5 level where you live and AQI to help determine when it is safe to exercise. 3- Do your part to decrease air pollution in your own life and encourage your community and country to do the same. 4- Consider a donation to the American Lung Association or spreading the word about the importance of healthy air by wearing an Air Health Our Health T-shirt or using a mug or tote (proceeds also go to supporting healthy air). ----------------------------------------------------------------------------------------- Visit episode post for more information, or go to airhealthourhealth.org. Follow and comment on Facebook page and Instagram. Record a question or comment on the Anchor podcast site or send an e-mail via the website. --- Send in a voice message: https://anchor.fm/airhealthourhealth/message

訂閱東森美洲電視頻道→https://bit.ly/2VF6dFI 訂閱東森美洲電視PODCAST→https://bit.ly/CASTTV 特斯拉搶攻家用空調 霸主大金為何驚呼「巨大威脅」？ 特斯拉熱泵型空調供應商 來自中國 透漏什麼玄機？ 2分鐘PM2.5下降約40% 特斯拉生化武器系統竟能救命？ 美股貪婪指數飆新高！熱錢派對近尾聲？貪婪比想像還更久？ 台灣錢淹到「肚擠」？！外匯存底、M1B續創高 熱錢派對何時結束？ 電動車概念「電池」先發動？！儲能系統「百倍商機」鋰鐵趨勢成形？ 華新科大馬廠員工染疫停工 晶片電阻吃緊 為何股價不漲？ 華新科出事、國巨肯定笑了？ 瑜亮情節鬥爭逾20年！？ 劉德音許台積電「三神蹟」 3奈米產能爆發「高階製程客戶」歸隊 --- Send in a voice message: https://anchor.fm/ettvamerica/message

FDA 批准HER2酪氨酸激酶抑制剂用于治疗HER2阳性的乳腺癌Lancet 低剂量阿司匹林可以预防初产妇早产？JAMA 男性补充叶酸和锌对精液质量和胎儿活产有影响吗？妥卡替尼（tucatinib）人表皮生长因子受体2 （HER2）阳性的、转移性乳腺癌患者在使用多种HER2靶向药物治疗后，若病情仍出现进展，则治疗选择便很有限。妥卡替尼（tucatinib）是一种口服的、HER2酪氨酸激酶的、高选择性抑制剂。2020年4月，妥卡替尼（tucatinib）被FDA批准用于治疗HER2阳性乳腺癌。《HER2CLIMB研究：妥卡替尼、曲妥珠单抗、卡培他滨治疗HER2阳性转移性乳腺癌的3期临床研究》New England Journal of Medicine，2020年2月 (1)研究纳入HER2阳性的、复发性、转移性乳腺癌患者共480人，在曲妥珠单抗和卡培他滨的联合治疗的基础上，随机联用妥卡替尼或安慰剂。联用妥卡替尼组和安慰剂组中，1年无进展生存率分别为33.1%和12.3%（疾病进展或死亡的风险比为0.54，P

Health Check Ep 48: Why is lung cancer no.1 killer among cancers? 14:48 mins Synopsis: Fortnightly on Wednesdays, get healthier living tips as The Straits Times chats with expert guests. With November being Lung Cancer Awareness Month, this episode looks at how lung cancer is the no.1 killer among cancers here in Singapore and globally, and will shed light on advanced treatments as well as how to minimise your chances of getting lung cancer. This episode is brought to you by MSD. ST senior health correspondent Joyce Teo hosts Dr Philip Eng, a senior consultant respiratory physician who has his own clinic - the Philip Eng Respiratory & Medical Clinic at the Mount Elizabeth Medical Centre. He has lectured in various countries, trained many doctors in the region, and published numerous articles. They discuss the following: 1. How can non-smokers get lung cancer? For air pollution, what is the WHO (World Health Organisation) standard for PM2.5 levels? (1:42) 2. How has lung cancer treatment evolved to today's gold standard of keyhole surgery, alongside other treatments such as stereotactic radiotherapy, safer chemotherapy drugs, immunotherapy and targeted therapy? (4:00) 4. Advice on how to protect yourself to cover the cost of such treatments: Buy good extra insurance coverage when you're young and fit (7:52) 5. Innovations in lung cancer treatments such as proton beam therapy and costs of such therapies (10:10) 6. Best way to decrease lung cancer risk factors and how smokers should do more effective CT lung scans instead of normal chest X-rays (12:27) Produced by: Joyce Teo (joyceteo@sph.com.sg), Ernest Luis and Penelope Lee Edited by: Adam Azlee Subscribe to Health Check Podcast channel, hear the latest episodes fortnightly on Wednesdays and rate us on your favourite audio apps: Channel: https://str.sg/JWaN Apple Podcasts: https://str.sg/JWRX Spotify: https://str.sg/JWaQ Google Podcasts: https://str.sg/J6Wv  Website: http://str.sg/stpodcasts Feedback to: podcast@sph.com.sg Read her stories: https://str.sg/JbxN See omnystudio.com/listener for privacy information.

Build a 3D printed enclosure for your IOT Air Quality Sensor. This project uses sensors to measure PM2.5 (particles that are 2.5 microns or smaller in diameter) dust concentrations, temperature and humidity. This weatherproof enclosure is modeled after a silo-home. We've included different types of mounting holes and brackets for different mounting configurations. Learn Guide: https://learn.adafruit.com/air-quality-sensor-silo-house/ PMS5003 Air Quality Sensor https://www.adafruit.com/product/3686 PMSA003I Air Quality Sensor https://www.adafruit.com/product/4632 BME280 Sensor https://www.adafruit.com/product/2652 BME680 Sensor https://www.adafruit.com/product/3660 Visit the Adafruit shop online - http://www.adafruit.com ----------------------------------------- LIVE CHAT IS HERE! http://adafru.it/discord Adafruit on Instagram: https://www.instagram.com/adafruit Subscribe to Adafruit on YouTube: http://adafru.it/subscribe New tutorials on the Adafruit Learning System: http://learn.adafruit.com/ -----------------------------------------

Build a 3D printed enclosure for your IOT Air Quality Sensor. This project uses sensors to measure PM2.5 (particles that are 2.5 microns or smaller in diameter) dust concentrations, temperature and humidity. This weatherproof enclosure is modeled after a silo-home. We've included different types of mounting holes and brackets for different mounting configurations. Learn Guide: https://learn.adafruit.com/air-quality-sensor-silo-house/ PMS5003 Air Quality Sensor https://www.adafruit.com/product/3686 PMSA003I Air Quality Sensor https://www.adafruit.com/product/4632 BME280 Sensor https://www.adafruit.com/product/2652 BME680 Sensor https://www.adafruit.com/product/3660 Visit the Adafruit shop online - http://www.adafruit.com ----------------------------------------- LIVE CHAT IS HERE! http://adafru.it/discord Adafruit on Instagram: https://www.instagram.com/adafruit Subscribe to Adafruit on YouTube: http://adafru.it/subscribe New tutorials on the Adafruit Learning System: http://learn.adafruit.com/ -----------------------------------------

In our constant belief that we are at war with nature and all of the germs, we are killing ourselves ever faster and it is ludicrous and sad because we have twenty, thirty years of data on the microbiome to know that it's the microbiome that prevents cancer, autoimmune disease, depression, anxiety, sleep disorders, and infertility; it's all the microbiome. Yet somehow, from this ridiculous fear story, suddenly the whole world including scientists are okay with killing every organism on earth. COVID19 is just a very sad, low-vibration event. - Dr. Zach Bush   More than ever, a voice like Dr. Zach Bush needs to be heard and because this has been our most popular episode this year, we are doing a special release of it today. The Radical Truth About COVID-19 For all of us, 2020 has been in many ways the year of the phoenix rising from the ashes. Right now we are still watching it burn down to the ground. So we invite you to listen to Dr. Zach Bush including 5 other guests in our CV19 Truth Series: Protecting Your Health Freedom This special edition 6-part CV19 Truth Series: Protecting Your Health Freedom podcast with host, Josh Trent, spotlights the best and most trusted information you will find in the online wellness world when it comes to taking your health and wellness into your own hands. Get 15% off your CURED Nutrition order with the code WELLNESSFORCE   ---> Get The Morning 21 System: A simple and powerful 21 minute system designed to give you more energy to let go of old weight and live life well.   JOIN THE FACEBOOK GROUP | *REVIEW THE PODCAST*   Wellness Force Radio Episode 345 Triple board-certified physician, Founder and CEO of ION*Biome and Executive Producer for the docu-series, Farmer's Footprint, Dr. Zach Bush, explains why COVID19 actually isn't a respiratory virus, explores humanity's awakening in the global shutdown, how spraying pesticides and insecticides has increased COVID19's impact and the use of hydroxychloroquine and cyanide poisoning kits against COVID19.   Is the approach to healing COVID19 patients with respirators all wrong? Discover what tools and methods might be the key to help heal COVID19 patients efficiently and quickly.   ION*Biome ***Get 15% off of your ION*Biome order with the code JOSH1KS  ION*Gut Health supports the body’s production of beneficial enzymes through redox signaling (cellular communication). Those beneficial enzymes support the tight junctions (the seals between cells) in our gut lining – the barrier protecting us from toxic substances like glyphosate and gluten while allowing the entry of beneficial nutrients. Keeping Your Gut Healthy It’s a critical barrier to keep strong so that a vibrant microbiome can flourish. Good health depends entirely on gut health because a lot more than digestion happens in the gut. It’s also where proper immune system function begins and the majority of our neurotransmitters, such as serotonin, are created. Say yes to ION*Gut Health and you are saying yes to optimal gut-brain connectivity and feel-good transmissions, protection from the toxins we face every day in our air, water, and food, immune function, digestive wellness, and supported gluten tolerance. ***Discount code cannot be applied to subscription orders Listen To Episode 345 As Dr. Zach Bush Uncovers:   [1:30] Humanity's Awakening In The Global Shutdown Dr. Zach Bush ION*Biome 344 Leslie Manookian Dr. Ben Lynch: Dirty Genes & COVID19 Joe Rogan's great media revolution, now brought to you by Spotify CURED Nutrition Zach Bush, MD On A Pandemic Of Possibility - Rich Roll Farmer's Footprint Intrinsic Health Series M Clinic The incredible work Dr. Zach has done to further improve our connection to the earth. How Mother Nature has designed herself so that when there is an extreme event, she responds with more life and biodiversity. Exploring what the virus really is and other past coronaviruses. How big data housing sites like Amazon are now able to know when a woman is pregnant even before she knows. Big data knows you’re pregnant (and that’s not all) How humanity is having a quickening as we enter this global shutdown due to the coronavirus. Why we needed this pause as we're in this metaphorical 'womb' even if it is not gentle on us. Ramifications from debt, substance abuse, to home abuse that have increased during the lockdown of the country. How human behavior has become a virus to Mother Earth and COVID19 is allowing her to heal. Why coronaviruses aren't anything new; we've seen them before for hundreds of years.   [16:00] Why COVID19 Actually Isn't A Respiratory Virus Looking at the stats of COVID19 and the fact that patients do not have a fever, do not have a low white blood cell count and do not have any change in their respiratory rate to conclude that COVID19 is a respiratory virus. What COVID19 actually is: a toxin poisoning to the red blood cell to a small percentage of people around the world in the cities with the highest rates of air pollution. Similarities between COVID19 symptoms and someone who has had cyanide poisoning; not pneumonia. (19:00) The importance of medical staff realizing that this is not some mysterious virus they should be afraid of as variants of it have already been introduced to humans in the past. How pharmaceuticals create an imbalance and put people at risk for cardiovascular disease, kidney disease, and diabetes during this "COVID19 pandemic." (24:00) The two drugs that the AMA demands be used to treat those three diseases above: ACE Inhibitors and Statin plus the fact that ACE Inhibitors cause the main COVID19 symptom, a cough, as it sensitizes the lung. Unpacking how exactly pharmaceuticals make people more susceptible to illness as the COVID19 virus is attached to other toxic particles in the air.   [25:00] How Spraying Insecticide Has Increased COVID19's Impact How our mortality significantly went up this year due to the toxicity of the planet with all of the pollution and chemicals dumped into the environment. Why spraying insecticide and toxic chemicals all over and into the air to try to sterilize the environment has increased COVID19's impact on humans. The importance of understanding that we are killing ourselves faster by harming the environment because our natural microbiome is what prevents disease and disorders. How to get out of the way of nature and just be in harmony with it for her health and our own as she continues to serve us. The importance of understanding the second law of thermodynamics: the total entropy of an isolated system can never decrease over time, and is constant if and only if all processes are reversible. (27:00) How the second law of thermodynamics applies to depression, disease, spirituality, business, economics, politics, and more. The fact that viruses are all around us: in our land, air, and ocean plus why they are not our enemies and we would be long gone thousands of years ago if they were. (30:00) The immense economic shift as the biggest consolidation of wealth (in just a couple of hands) in human history takes advantage of the COVID19 hype and fear. Price-Pottenger The Weston A. Price Foundation 321 Sally Fallon Morell & Hilda Labrada Gore   [31:00] Use of Hydroxychloroquine And Cyanide Poisoning Kits Against COVID19 Unpacking the fact that Wuhan has the most damaged ecosystem on the planet with all of the glyphosate being sprayed and has the biggest production of chemical raised pork thus this toxic stew of their microbiome is sending out an important genomic update to the rest of the world. Similarities between SARS and COVID19 symptoms including the approach to stopping them. What a hypoxic injury is as cyanide and other toxins enter red blood cells thus making the use of a respirator useless. (33:00) Unpacking why COVID19 patients are not dying from a lack of respiratory capacity, lack of oxygen in the atmosphere, or lack of oxygen in the respirator machine but from their lack of oxygen-carrying capacity. The importance of treating a COVID19 patient's hemoglobin; not the respiratory system because this is about healing a blood toxin; not a respiratory virus. How hydroxychloroquine changes the shape of the red blood cell and could actually be one of the very few medicines to increase the body's capacity to carry oxygen. The powerful impact that could happen to treat COVID19 in minutes when we use a simple cyanide poisoning kit that every hospital has vs having patients weeks on a respirator that might not even help them. (35:00)   [41:00] The Man-Made Environmental Devastation Created On Farms How Mother Earth is doing throughout all of this as she tries to breathe through her soils and oceans. The devastation that our planet has gone through including the impact of Roundup being sprayed everywhere. Soil Health Academy Dr. Allen Williams This is Your Brain on "Food Chemistry" How overplowing a field kills the mycelia or life beneath the topsoil thus causing it to lose important nutrients. Why we'll continue to see more coronaviruses impacting humanity as our air quality continues to suffer from CO2, methane, PM2.5, and other greenhouse gases. (47:50) The fact that PM2.5 is the least of our concerns if we realize that the oceans continue to take more and more CO2 and acidify which would wipe out 85% to 97% of life on earth. How we've gotten to the point of being in the midst of the planet's 6th extinction as we've already wiped out 50% of our biology and accelerating. The incredible new life that will be born on this planet when we really start to care about the planet and stop our harmful behavior. Unpacking the grand misperception that America is feeding the world when it's really just 30% as we continue to spray out chemicals onto all of our crops that have adopted mega farming. The reality that 70% of 7 billion people on earth are fed by traditional farming practices in poor countries with small amounts of farmland as farmers are abused by economic rules and lose out to the big corporation competition. How to directly help farmers in your community by buying CSA labeled foods.   [59:00] ION*Biome & The Gut-Brain Access His product, ION*Biome, and how it helps to improve our gut-brain access for great physical, emotional, and mental health. Exploring what REDOX science is: Reduction and Oxidation and its impacts on our health. His past and current research on cancer, healing the body, and how he came to create ION*Biome. Unpacking how our exosomes of genetic information from our genome could change behavior just like a virus of other cells. Breaking down our genetic DNA and RNA in relation to bacteria and fungi in our environment plus the food we just ate that's updating our genome. The fact that we have microbiome all throughout our bodies and even in the brain. Our natural biological methodologies for cellular communication across life forms at a deeper level. Exploring time, space, and this continuous vibration of the electromagnetic field that connects all of us. How we manifest events around us as the body absorbs and sends out intentions or information to the universe.   [1:16:00] Connecting The Head & The Heart Organizing our priorities to be able to be there for the people in our lives that mean the most to us. Why there is an opportunity to grow and be more when we feel disappointed that we aren't able to be present for others. How we get so caught up in life that we forget to pause and give gratitude for everything we experience and are as humans. The true calling of physicians and health care workers plus his personal message for them. Exploring the intelligence of the physical and spiritual worlds in our universe. Why a microscopic boundary is the beginning of self-identity and healthy macro boundaries: spiritual and emotional. How to let go and surrender by stop holding onto everything you believe from the roles you have played to the identities you've taken on. Patrick Gentempo The deep spiritual conversation he was gifted to have with Patrick Gentempo. Unpacking Patrick Gentempo's message: Humanity is dying largely because we keep thinking that the fabric of life is love; the fabric of the universe we live in is beauty. Love is not a thing, action, or result; love is the experience of witnessing beauty. Why we can't manifest love; all we can do is see the beauty and react to that. Through that, we will be a vessel of love. Explaining why you don't lack self-love; you just haven't given yourself the breath and time to find your own beauty. Jenn Perell Bush M21 Wellness Guide Wellness Force Community Power Quotes From The Show How To Improve A COVID19 Patient's Oxygen-Carrying Capacity   "It turns out that the main thing hydroxychloroquine does is change the shape of the red blood cell. Malaria is a parasite that attacks the red blood cell and so hydroxychloroquine, as it turns out, is one of the few medications someone could reach for to help improve the oxygen-carrying capacity of the blood. Now there's a much more efficient approach called a cyanide poisoning kit that takes just three quick injections to change the shape of the hemoglobin into methemoglobin and it does fine. We can treat a COVID19 patient with a simple cyanide poisoning kit that every hospital has in a matter of minutes rather than weeks on a respirator where the patient is dying from pneumonia." - Dr. Zach Bush   Becoming A Vessel Of Love "We don't have to manifest love; in fact, we cannot manifest love. All we can do is see beauty and react to that. Through that, we will be a vessel of love and we will pour love through ourselves not because we know how to love but because we can recognize beauty. So, for everyone trying to struggle with why you don't have self-love, it's not because you don't love yourself, it's because you just haven't given yourself the breath and the time to find your own beauty. So, find that beauty, dig in, and you're going to be able to love like you've never known before." - Dr. Zach Bush     The Toxicity Of Our Chemical Fears, Response, & Behavior "We're seeing a lot of people dying from heart disease, cancer, and autoimmune conditions right now. Our mortality went up this year significantly because of the toxicity of the planet. We've never dumped more chemicals than we have in the last year and I don't think it's surprising necessarily that the US is seeing some of the highest mortality right now because as soon as we thought this was a virus killing us, we went and sprayed insecticide and toxic chemicals into the air all over South Korea and China. All of those toxins then went airborne and ended up in cities like Seattle and New York a couple of weeks later. That band of air that is traveling across the globe all the time is carrying the toxicity of our chemical fear and response to a toxin that was developed from our chemical behavior of transportation and energy sectors." - Dr. Zach Bush     How Does COVID-19 Actually Impact Us? "Our patients are dying from a lack of oxygen-carrying capacity not a lack of respiratory capacity or lack of oxygen in the atmosphere or lack of oxygen in the respirator machine. They're dying because we're not treating the hemoglobin." - Dr. Zach Bush   Links From Today's Show  CURED Nutrition ION*Biome 344 Leslie Manookian Dr. Ben Lynch: Dirty Genes & COVID19 Zach Bush, MD On A Pandemic Of Possibility - Rich Roll Joe Rogan's great media revolution, now brought to you by Spotify Farmer's Footprint Intrinsic Health Series M Clinic Leave Wellness Force a review on iTunes Big data knows you’re pregnant (and that’s not all) Price-Pottenger The Weston A. Price Foundation 321 Sally Fallon Morell & Hilda Labrada Gore Soil Health Academy Dr. Allen Williams This is Your Brain on "Food Chemistry" Patrick Gentempo Jenn Perell Bush M21 Wellness Guide Wellness Force Community Dr. Zach Bush Facebook Twitter Instagram YouTube   About Dr. Zach Bush Dr. Zach Bush is a physician specializing in internal medicine, endocrinology, and hospice care. He is an internationally recognized educator and thought leader on the microbiome as it relates to health, disease, and food systems.     CURED Nutrition Get 15% off your CURED Nutrition order with the code WELLNESSFORCE It's taken me over a year to find the right hemp and CBD company to introduce to the Wellness Force Community and I could not be more thrilled that it's CURED Nutrition! CURED Nutrition is a movement inspired by nature and grounded in a shared desire to leave a lasting impression on you, our community, and this world. Together, they're a collective of heart-centered human beings who are inviting you – the conscious creatives, dreamers, and healers – to join their family. Learn how CURED hemp and CBD products can enhance your daily wellness routine. Try Cured Today They're Colorado-based organically grown hemp products that have been engineered to transform your approach toward an elevated life. Tap into your inherent potential – your greatest mind-body alignment – and nourish it with the supplements you were designed to thrive on. A greater existence is waiting.   More Top Episodes 226 Paul Chek: The Revolution Is Coming (3 Part Series) 131 Drew Manning: Emotional Fitness 129 Gretchen Rubin: The Four Tendencies  183 Dr. Kyra Bobinet: Brain Science 196 Aubrey Marcus: Own The Day 103 Robb Wolf: Wired To Eat Best of The Best: The Top 10 Guests From over 200 Shows Get More Wellness In Your Life (for free) Join the Wellness Force Community on Facebook Get the M21 Calm Mind + Immunity Boosting Guide

What would happen in terms of our health and wealth if we started only purcashing electric vehicles by the year 2030? Today on the podcast I talk to Will Barrett of the American Lung Association about the new analysis the ALA has commissioned called the Road to Clean Air. We recorded this with sky high levels of PM2.5 outside due to wildfires worsened by climate change, and it was an analysis that gave me some hope on the dual benefits of addressing climate change and decreasing particulate matter. Furthermore, Will is hopeful that we can actually achieve these goals. Listen to the podcast today for a dose of hope, then take action for healthy air in your own life. What Can You Do? 1- Speak up about the health of clean air- you can sign the ALA's petition to your local Governor to focus on healthy air here. Write a letter to the editor of your local paper. Post about the importance of clean air with the #Standupforcleanair. 2- Ask your representatives at all levels of government, including your state legislature to incentivize electric vehicles. Ask your state, town or county to only purchase electric vehicles- frequently a municipality has bulk purchasing power and can invest in infrastructure that makes electrification more possible for individuals and businesses. 3- Donate to the ALA here- show support from the Air Health Our Health community! 4- Are you considering purchasing a new car soon? Choose electric! Or a plug-in hybrid with a decent range if you're not ready to go full electric. Consumer Reports estimates a typical EV owner can save $800-$1000 on fuel costs especially if they charge at home, and lifetime savings of $4,600 on vehicle maintenance, oil changes, etc. --------------------------------------------------------------------------------- See the blog post for more information and references, or go to airhealthourhealth.org. Follow and comment on Facebook page and Instagram. Record a question or comment on the Anchor podcast site or send an e-mail via the website. --- Send in a voice message: https://anchor.fm/airhealthourhealth/message

This week's EYE on NPI is a breath of fresh air! How do we know it's fresh? Cause we have a brand new Sensirion SGP40 air quality sensor (https://www.digikey.com/en/product-highlight/s/sensirion/sgp40-d-r4) hooked up and ready to be our digital nose. We loooove Sensirion sensors, and we stock a whole bunch in the Adafruit shop. (https://www.adafruit.com/?q=sensirion&sort=BestMatch) They are renowned for their excellent prices and quality on temperature, humidity and gas sensors, so when we saw this pop up on Digi-Key at https://www.digikey.com/new, we quickly picked up a few pieces to check out. The SGP40 is Sensirion’s digital volatile organic compounds (VOC) sensor designed for easy integration into air treatment devices and air quality monitors. Based on Sensirion’s CMOSens® technology, the SGP40 offers a complete sensor system on a single chip and features a digital I²C interface, a temperature-controlled micro-hotplate, and a humidity-compensated indoor air quality signal. In combination with Sensirion’s powerful VOC algorithm, the sensor signal can be directly used to evaluate indoor air quality for applications such as triggering the gradual fan control of an air treatment device. Both the SGP40 chip and VOC algorithm feature unrivaled robustness in the final application over their lifetimes. Pushing the multi-pixel and multi-hotplate approach to the next level of individual control of each sensing element, the SGP40 enables a drastic reduction in power consumption, making it suitable for battery-driven applications as well. Sensirion’s state-of-the-art production process guarantees high reproducibility and reliability. Gas sensors are really interesting, they are all essentially resistive sensors, where the exposed silicon has a metal oxide layer (MOX) that is susceptible to ambient gasses. There's a heater element that you need to turn on, then wait till the silicon chunk can react with the air. The resistance changes with the amount of organic compounds in the air and you can measure the resistive differences. (https://www.sensirion.com/en/environmental-sensors/gas-sensors/) Now for many gas sensors, you basically get 4 pins: two for the heater, and two for the resistor. You have to power the heater, then use a resistor divider or op-amp to read the resistance and back calculate. There's no built-in calibration available. What we like about the SGPx0 series is that you don't need the power control or analog input. This isn't Sensirion's first gas sensor, we've already stocked the SGP30 for a while, (https://www.digikey.com/product-detail/en/adafruit-industries-llc/3709/1528-2531-ND/8258468) and there are a few things we really liked about that sensor that are the same on the SGP40. First is a dead-simple I2C interface, you send it some commands, it responds with the normalized resistance data reading. No complex code required, it's trivial to port to any microcontroller. With a humidity sensor on the same microcontroller, you can feed the ambient RH to the SGP40 and it will improve the resistance calculation. Check out the SGP40 at Digi-Key at https://www.digikey.com/short/zwzjqb May we suggest one of the fine SHT3x series? (https://www.digikey.com/product-detail/en/sensirion-ag/SHT35-DIS-F2-5KS/1649-1067-6-ND/6212141) A PM2.5 sensor can also be added for a powerful all-in-one environmental-sensing kit (https://www.digikey.com/products/en?keywords=sensirion%20pm2.5) See Sensirion's video at https://www.youtube.com/watch?v=dCCfbYf1PNk

Anne is an Environmental Justice Research Assistant intern with us at BREDL and a grad student at Duke University. She is working to help community members learn how to use Zoom and organize digitally and investigate COVID incidence across EJ communities in NC. Nanda Gupal is a Research Assistant intern with us at BREDL and a graduate student getting his Master of Engineering Management at Duke University and he is studying the health impacts of PM2.5 from the various non-mobile sources in the states of Virginia, North Carolina, South Carolina, Georgia, Tennessee and Alabama. The study includes trend analysis on the various aspects of PM2.5 effects in these states. Contact and connect with Anne and Nanda: anne.crabill@duke.edu and nandagopal.suresh@duke.edu PM 2.5: https://www.health.ny.gov/environmental/indoors/air/pmq_a.htm https://www.epa.gov/pm-pollution/particulate-matter-pm-basics How to find your levels: https://www.epa.gov/air-trends/particulate-matter-pm25-trends Environmental Justice Communities during COVID: https://www.greenamerica.org/blog/how-environmental-justice-connects-covid-19 Background Music Credits: https://www.youtube.com/c/mbbmusic https://soundcloud.com/mbbofficial https://www.instagram.com/mbb_music

CircuitPythonista Jepler requested that the QT Py have a spot for external flash chip on the bottom for expansion. Your wish is my command! Voila rev B, with a SOIC 8 on the bottom connected to a hardware SPI port. Not much else changed here, it is ready for another prototype revision and maybe a pretty silkscreen! ...and! here is the QT Py with lots of STEMMA QT devices: OLEDs and sensors - oh my! The QT Py is a SAMD21 board that can plug n play with any of our 50+ STEMMA QT boards, like this 128x128 OLED, PM2.5 Air Quality sensor, pressure/humidity/temp sensor and 9-DoF IMU. No soldering required, this is the easiest way to build electronics...coming soon to the adafruit shop! http://adafruit.com/qtpy #circuitpython #adafruit #qtpy Visit the Adafruit shop online - http://www.adafruit.com ----------------------------------------- LIVE CHAT IS HERE! http://adafru.it/discord Adafruit on Instagram: https://www.instagram.com/adafruit Subscribe to Adafruit on YouTube: http://adafru.it/subscribe New tutorials on the Adafruit Learning System: http://learn.adafruit.com/ -----------------------------------------

在今年疫情爆發之前，所有空氣清淨機幾乎都只注重 PM2.5 懸浮微粒的濾淨，對於滅除細菌病毒功能並沒有太在意，只有少數品牌特別配備殺菌功能。隨著疫情延燒，讓人們紛紛回頭檢視自己的空氣清淨機是不是可以殺菌，但通常得到的都是失望。要怎麼知道你的空氣清淨機有沒有滅菌功能呢？你只要確認清淨機是否有 UV 紫外線燈、臭氧或是電漿，因為這三種技術是真的可以滅菌，而不只是吸附病菌。 這集《科技酷宅》特輯特別邀請克立淨空氣清淨機的行家 Parcy 來跟大家聊聊，空氣清淨機的各種原理，以及使用空氣清淨機應該注意的各種事項。歡迎收聽。

This week, we’re talking about the impacts of rollbacks at the Environmental Protection Agency and a bill at the Statehouse to protect South Carolina wildlife. Public Concern is the weekly podcast from the South Carolina Conservation Coalition. The name of our podcast comes from Article 12 of the South Carolina Constitution, which is all about the functions of government: “The health, welfare, and safety of the lives and property of the people of this State...and the conservation of its natural resources are matters of public concern.” Subscribe, and send any questions you'd like for us to discuss at publicconcernpodcast@gmail.com. You can find out more at publicconcernpodcast.org.The Conservation Coalition webinar serieshttps://www.cvsc.org/featured-post/webinar-series-conversations-conservationists/Harvard Study on the relationship between PM2.5 and Covid-19https://projects.iq.harvard.edu/covid-pm/homeAyana Elizabeth Johnson: I’m a black climate expert. Racism derails our efforts to save the planet.https://www.washingtonpost.com/outlook/2020/06/03/im-black-climate-scientist-racism-derails-our-efforts-save-planet/Amy Armstrong: Clean air on the chopping block amid pandemichttps://www.postandcourier.com/health/covid19/commentary-clean-air-on-the-chopping-block-amid-pandemic/article_60a50600-7fec-11ea-894f-2343907634f5.htmlU.S. EPA proposes changes to how clean air rules are writtenhttps://www.reuters.com/article/us-usa-epa-regulation/u-s-epa-proposes-changes-to-how-clean-air-rules-are-written-idUSKBN23B2QVWhat Trump’s permit order means for NEPA, energy and racehttps://www.eenews.net/stories/1063324751Recreating Responsibly https://www.rei.com/blog/news/recreate-responsiblyThe South Carolina Wildlife Federation http://www.scwf.org/The South Carolina Statehouse https://www.scstatehouse.gov/Music:Beauty Flow by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/5025-beauty-flowLicense: http://creativecommons.org/licenses/by/4.0/

In this episode (46:42) All information is researched but not exhaustive and not reviewed by an outside expert. Although Esteban is a licensed physician, this is NOT medical advice → you should get medical advice specific to your situation and health from your doctor, not from us or this podcast.  CLICK HERE to download this outline as a PDF Why Should We Wear Masks? Study came out 3 weeks ago titled “Universal Masking is Urgent in the COVID-19 Pandemic:SEIR and Agent Based Models, Empirical Validation, Policy Recommendations” The authors (who are from Hong Kong, UK, France and Finland) compared countries with high levels of mask-wearing to ones with low levels. Using computer modeling and real-world data, they found masks could reduce transmission. The study concluded that if 80% of the population wore masks, there would be more than a 90% drop in infection rates. Etiquette and Politics Concerning Masks Wearing a mask does not give sick people permission to attend a trial. Allergies and upper respiratory infections can look similar, don’t assume the best case (that you have allergies). Instead, assume you are sick and stay home. Risk tolerance is key, but this is subjective and based on personal risk factors. However, understand that you will likely be unhappy for two different reasons: Either you feel that there are not enough rules in place (and/or too many violations) so that you don’t feel comfortable being there because you fear getting the virus. If so, STAY HOME. Or you feel that there are too many rules in place (and they are unnecessary) so that you don’t feel comfortable being there because people are upset with you for “bending” or breaking the rules. If so, STAY HOME. Sample statement from AKC premium: “If you are concerned about the possibility of exposure to the coronavirus OR if you are unwilling to follow the states rules, it would be best if you did not enter this July trial.” Every personal situation is addressed by that statement. CDC Guidelines Who Should Wear? People older than 2 years of age in public settings where other social distancing measures are difficult to maintain Who Should Not Wear? Anyone who has trouble breathing, or is unconscious, incapacitated or otherwise unable to remove the mask without assistance. In Esteban’s opinion, these people should not be at agility trials because they are at high risk for complications from coronavirus infection. General Considerations Fit snugly but comfortably against the side of the face. Comfort is important. Kap 7 masks 82% Polyester/18% elastane Shopping time, you should have a mask for every day of the week, like underwear! Children require a smaller fit. Leave your children at home. Leave guests at home–don’t bring them to agility trials. If it doesn’t fit well, especially around the nose, you will suck in unfiltered air from around your face. Include multiple layers of fabric PM2.5 N95 Activated Carbon Filter Mask Insert (100 for $100) Blocks at least 95% of viruses as small as 0.3 microns Virus even smaller but carried on droplets that are 5-10 microns Thread count of 180 or better for materials like sheets/pillowcases HEPA vacuum bags (hard to breathe) NO A/C BAGS DUE TO FIBERGLASS Be secured with ties or ear loops. Ties are more adjustable than a rubber band behind the ear! Metal to form the nose helps contour the mask to avoid gaps Allow for breathing without restriction. Remove very carefully, don’t touch the mask part, just touch the ties. Be able to be laundered and machine-dried without damage or change to shape. Air dry is okay, leave it in the sun if possible. Hotter is better than colder for washing and drying. Two situations for masks: low risk and high risk. Agility trials will be high risk. Crowded grocery stores are high risk. Walking outdoors alone is low risk. Use your filters and higher quality masks for higher risk situations and opt for comfort and no filters in low risk situations. Special Dog Agility Considerations Your dog’s comfort level with masks Other dogs’ comfort level with masks Difference in your voice Difference in facial expression The American Kennel Club (AKC) is deferring to clubs in that they should “consider recommending that exhibitors wear masks. Exhibitors should be able to run without a mask if they desire. Judges may wear masks at their discretion if not required by the club.” See the document here: https://s3.amazonaws.com/cdn-origin-etr.akc.org/wp-content/uploads/2020/05/12160607/Agility-Covid-19-Suggested-Best-Practices.pdf CPE Guidelines effective May 11: http://www.k9cpe.com/premiums/covid19letter05112020.pdf Philosophy: As dog sports are very “social”, we are choosing not to use the term“social distancing” rather refer to it as “physical distancing”. MASKS: Masks are to be worn by anyone within the ring (building, walking, running, judging). Masks are up to the individual, club, local, state and government guidelines when not within the ring. Exhibitors who will be wearing masks will need to bring enough masks for the duration of the trial and dispose of single use masks properly. Make sure your dog is ok with people wearing masks. We don’t want a dog becoming fearful due to something they’ve never seen before. From Esteban: We can come together as a community in order to save our sport and rebuild it in the coming years. Resources: We should wear masks study is here: https://www.researchgate.net/publication/340933456_Universal_Masking_is_Urgent_in_the_COVID-19_Pandemic_SEIR_and_Agent_Based_Models_Empirical_Validation_Policy_Recommendations CDC guidelines here: https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/about-face-coverings.html Mayo Clinic interview about masks here: https://newsnetwork.mayoclinic.org/discussion/covid-19-mayo-clinic-expert-answers-questions-about-masks-after-cdc-updates-its-recommendation/ Video: Pulmonologist Marjorie Patricia George MD demonstrates how to put on and remove a cloth mask properly https://youtu.be/iGE5eny_9gA Order swim suit material masks here: https://www.kap7.com/masks-1/ Order masks with metal nose bridge and pocket inserts here: https://www.masqd.com/collections/masks Order mask filters here: https://www.masqd.com/collections/masks/products/mask-filter AKC Guidelines here: https://s3.amazonaws.com/cdn-origin-etr.akc.org/wp-content/uploads/2020/05/12160607/Agility-Covid-19-Suggested-Best-Practices.pdf USDAA Guidelines here: https://usdaa.com/news/best-practices-when-agility-events-return.cfm CPE Guidelines here: http://www.k9cpe.com/premiums/covid19letter05112020.pdf

Our patients are dying from a lack of oxygen-carrying capacity not a lack of respiratory capacity or lack of oxygen in the atmosphere or lack of oxygen in the respirator machine. They're dying because we're not treating the hemoglobin. - Dr. Zach Bush   Is the approach to healing COVID19 patients with respirators all wrong? Get 15% off your CURED Nutrition order with the code WELLNESSFORCE   ---> Get The Morning 21 System: A simple and powerful 21 minute system designed to give you more energy to let go of old weight and live life well.   JOIN THE FACEBOOK GROUP | *REVIEW THE PODCAST*   Wellness Force Radio Episode 345 Triple board-certified physician, Founder and CEO of ION*Biome and Executive Producer for the docu-series, Farmer's Footprint, Dr. Zach Bush, explains why COVID19 actually isn't a respiratory virus, explores humanity's awakening in the global shutdown, how spraying pesticides and insecticides has increased COVID19's impact and the use of hydroxychloroquine and cyanide poisoning kits against COVID19. Discover what tools and methods might be the key to help heal COVID19 patients efficiently and quickly.   ION*Biome ***Get 15% off of your ION*Biome order with the code JOSH1KS  ION*Gut Health supports the body’s production of beneficial enzymes through redox signaling (cellular communication). Those beneficial enzymes support the tight junctions (the seals between cells) in our gut lining – the barrier protecting us from toxic substances like glyphosate and gluten while allowing the entry of beneficial nutrients. Keeping Your Gut Healthy It’s a critical barrier to keep strong so that a vibrant microbiome can flourish. Good health depends entirely on gut health because a lot more than digestion happens in the gut. It’s also where proper immune system function begins and the majority of our neurotransmitters, such as serotonin, are created. Say yes to ION*Gut Health and you are saying yes to optimal gut-brain connectivity and feel-good transmissions, protection from the toxins we face every day in our air, water, and food, immune function, digestive wellness, and supported gluten tolerance. ***Discount code cannot be applied to subscription orders Listen To Episode 345 As Dr. Zach Bush Uncovers:   [1:30] Humanity's Awakening In The Global Shutdown Dr. Zach Bush ION*Biome 344 Leslie Manookian Dr. Ben Lynch: Dirty Genes & COVID19 Joe Rogan's great media revolution, now brought to you by Spotify CURED Nutrition Zach Bush, MD On A Pandemic Of Possibility - Rich Roll Farmer's Footprint Intrinsic Health Series M Clinic The incredible work Dr. Zach has done to further improve our connection to the earth. How Mother Nature has designed herself so that when there is an extreme event, she responds with more life and biodiversity. Exploring what the virus really is and other past coronaviruses. How big data housing sites like Amazon are now able to know when a woman is pregnant even before she knows. Big data knows you’re pregnant (and that’s not all) How humanity is having a quickening as we enter this global shutdown due to the coronavirus. Why we needed this pause as we're in this metaphorical 'womb' even if it is not gentle on us. Ramifications from debt, substance abuse, to home abuse that have increased during the lockdown of the country. How human behavior has become a virus to Mother Earth and COVID19 is allowing her to heal. Why coronaviruses aren't anything new; we've seen them before for hundreds of years.   [16:00] Why COVID19 Actually Isn't A Respiratory Virus Looking at the stats of COVID19 and the fact that patients do not have a fever, do not have a low white blood cell count and do not have any change in their respiratory rate to conclude that COVID19 is a respiratory virus. What COVID19 actually is: a toxin poisoning to the red blood cell to a small percentage of people around the world in the cities with the highest rates of air pollution. Similarities between COVID19 symptoms and someone who has had cyanide poisoning; not pneumonia. (19:00) The importance of medical staff realizing that this is not some mysterious virus they should be afraid of as variants of it have already been introduced to humans in the past. How pharmaceuticals create an imbalance and put people at risk for cardiovascular disease, kidney disease, and diabetes during this "COVID19 pandemic." (24:00) The two drugs that the AMA demands be used to treat those three diseases above: ACE Inhibitors and Statin plus the fact that ACE Inhibitors cause the main COVID19 symptom, a cough, as it sensitizes the lung. Unpacking how exactly pharmaceuticals make people more susceptible to illness as the COVID19 virus is attached to other toxic particles in the air.   [25:00] How Spraying Insecticide Has Increased COVID19's Impact How our mortality significantly went up this year due to the toxicity of the planet with all of the pollution and chemicals dumped into the environment. Why spraying insecticide and toxic chemicals all over and into the air to try to sterilize the environment has increased COVID19's impact on humans. The importance of understanding that we are killing ourselves faster by harming the environment because our natural microbiome is what prevents disease and disorders. How to get out of the way of nature and just be in harmony with it for her health and our own as she continues to serve us. The importance of understanding the second law of thermodynamics: the total entropy of an isolated system can never decrease over time, and is constant if and only if all processes are reversible. (27:00) How the second law of thermodynamics applies to depression, disease, spirituality, business, economics, politics, and more. The fact that viruses are all around us: in our land, air, and ocean plus why they are not our enemies and we would be long gone thousands of years ago if they were. (30:00) The immense economic shift as the biggest consolidation of wealth (in just a couple of hands) in human history takes advantage of the COVID19 hype and fear. Price-Pottenger The Weston A. Price Foundation 321 Sally Fallon Morell & Hilda Labrada Gore   [31:00] Use of Hydroxychloroquine And Cyanide Poisoning Kits Against COVID19 Unpacking the fact that Wuhan has the most damaged ecosystem on the planet with all of the glyphosate being sprayed and has the biggest production of chemical raised pork thus this toxic stew of their microbiome is sending out an important genomic update to the rest of the world. Similarities between SARS and COVID19 symptoms including the approach to stopping them. What a hypoxic injury is as cyanide and other toxins enter red blood cells thus making the use of a respirator useless. (33:00) Unpacking why COVID19 patients are not dying from a lack of respiratory capacity, lack of oxygen in the atmosphere, or lack of oxygen in the respirator machine but from their lack of oxygen-carrying capacity. The importance of treating a COVID19 patient's hemoglobin; not the respiratory system because this is about healing a blood toxin; not a respiratory virus. How hydroxychloroquine changes the shape of the red blood cell and could actually be one of the very few medicines to increase the body's capacity to carry oxygen. The powerful impact that could happen to treat COVID19 in minutes when we use a simple cyanide poisoning kit that every hospital has vs having patients weeks on a respirator that might not even help them. (35:00)   [41:00] The Man-Made Environmental Devastation Created On Farms How Mother Earth is doing throughout all of this as she tries to breathe through her soils and oceans. The devastation that our planet has gone through including the impact of Roundup being sprayed everywhere. Soil Health Academy Dr. Allen Williams This is Your Brain on "Food Chemistry" How overplowing a field kills the mycelia or life beneath the topsoil thus causing it to lose important nutrients. Why we'll continue to see more coronaviruses impacting humanity as our air quality continues to suffer from CO2, methane, PM2.5, and other greenhouse gases. (47:50) The fact that PM2.5 is the least of our concerns if we realize that the oceans continue to take more and more CO2 and acidify which would wipe out 85% to 97% of life on earth. How we've gotten to the point of being in the midst of the planet's 6th extinction as we've already wiped out 50% of our biology and accelerating. The incredible new life that will be born on this planet when we really start to care about the planet and stop our harmful behavior. Unpacking the grand misperception that America is feeding the world when it's really just 30% as we continue to spray out chemicals onto all of our crops that have adopted mega farming. The reality that 70% of 7 billion people on earth are fed by traditional farming practices in poor countries with small amounts of farmland as farmers are abused by economic rules and lose out to the big corporation competition. How to directly help farmers in your community by buying CSA labeled foods.   [59:00] ION*Biome & The Gut-Brain Access His product, ION*Biome, and how it helps to improve our gut-brain access for great physical, emotional, and mental health. Exploring what REDOX science is: Reduction and Oxidation and its impacts on our health. His past and current research on cancer, healing the body, and how he came to create ION*Biome. Unpacking how our exosomes of genetic information from our genome could change behavior just like a virus of other cells. Breaking down our genetic DNA and RNA in relation to bacteria and fungi in our environment plus the food we just ate that's updating our genome. The fact that we have microbiome all throughout our bodies and even in the brain. Our natural biological methodologies for cellular communication across life forms at a deeper level. Exploring time, space, and this continuous vibration of the electromagnetic field that connects all of us. How we manifest events around us as the body absorbs and sends out intentions or information to the universe.   [1:16:00] Connecting The Head & The Heart Organizing our priorities to be able to be there for the people in our lives that mean the most to us. Why there is an opportunity to grow and be more when we feel disappointed that we aren't able to be present for others. How we get so caught up in life that we forget to pause and give gratitude for everything we experience and are as humans. The true calling of physicians and health care workers plus his personal message for them. Exploring the intelligence of the physical and spiritual worlds in our universe. Why a microscopic boundary is the beginning of self-identity and healthy macro boundaries: spiritual and emotional. How to let go and surrender by stop holding onto everything you believe from the roles you have played to the identities you've taken on. Patrick Gentempo The deep spiritual conversation he was gifted to have with Patrick Gentempo. Unpacking Patrick Gentempo's message: Humanity is dying largely because we keep thinking that the fabric of life is love; the fabric of the universe we live in is beauty. Love is not a thing, action, or result; love is the experience of witnessing beauty. Why we can't manifest love; all we can do is see the beauty and react to that. Through that, we will be a vessel of love. Explaining why you don't lack self-love; you just haven't given yourself the breath and time to find your own beauty. Jenn Perell Bush M21 Wellness Guide Wellness Force Community Power Quotes From The Show How To Improve A COVID19 Patient's Oxygen-Carrying Capacity   "It turns out that the main thing hydroxychloroquine does is change the shape of the red blood cell. Malaria is a parasite that attacks the red blood cell and so hydroxychloroquine, as it turns out, is one of the few medications someone could reach for to help improve the oxygen-carrying capacity of the blood. Now there's a much more efficient approach called a cyanide poisoning kit that takes just three quick injections to change the shape of the hemoglobin into methemoglobin and it does fine. We can treat a COVID19 patient with a simple cyanide poisoning kit that every hospital has in a matter of minutes rather than weeks on a respirator where the patient is dying from pneumonia." - Dr. Zach Bush   Becoming A Vessel Of Love "We don't have to manifest love; in fact, we cannot manifest love. All we can do is see beauty and react to that. Through that, we will be a vessel of love and we will pour love through ourselves not because we know how to love but because we can recognize beauty. So, for everyone trying to struggle with why you don't have self-love, it's not because you don't love yourself, it's because you just haven't given yourself the breath and the time to find your own beauty. So, find that beauty, dig in, and you're going to be able to love like you've never known before." - Dr. Zach Bush     The Toxicity Of Our Chemical Fears, Response, & Behavior "We're seeing a lot of people dying from heart disease, cancer, and autoimmune conditions right now. Our mortality went up this year significantly because of the toxicity of the planet. We've never dumped more chemicals than we have in the last year and I don't think it's surprising necessarily that the US is seeing some of the highest mortality right now because as soon as we thought this was a virus killing us, we went and sprayed insecticide and toxic chemicals into the air all over South Korea and China. All of those toxins then went airborne and ended up in cities like Seattle and New York a couple of weeks later. That band of air that is traveling across the globe all the time is carrying the toxicity of our chemical fear and response to a toxin that was developed from our chemical behavior of transportation and energy sectors." - Dr. Zach Bush     Our Constant War With Nature "In our constant belief that we are at war with nature and all of the germs, we are killing ourselves ever faster and it is ludicrous and sad because we have twenty, thirty years of data on the microbiome to know that it's the microbiome that prevents cancer, autoimmune disease, depression, anxiety, sleep disorders, and infertility; it's all the microbiome. Yet somehow, from this ridiculous fear story, suddenly the whole world including scientists are okay with killing every organism on earth. COVID19 is just a very sad, low-vibration event." - Dr. Zach Bush   Links From Today's Show  CURED Nutrition ION*Biome 344 Leslie Manookian Dr. Ben Lynch: Dirty Genes & COVID19 Zach Bush, MD On A Pandemic Of Possibility - Rich Roll Joe Rogan's great media revolution, now brought to you by Spotify Farmer's Footprint Intrinsic Health Series M Clinic Leave Wellness Force a review on iTunes Big data knows you’re pregnant (and that’s not all) Price-Pottenger The Weston A. Price Foundation 321 Sally Fallon Morell & Hilda Labrada Gore Soil Health Academy Dr. Allen Williams This is Your Brain on "Food Chemistry" Patrick Gentempo Jenn Perell Bush M21 Wellness Guide Wellness Force Community Dr. Zach Bush Facebook Twitter Instagram YouTube   About Dr. Zach Bush Dr. Zach Bush is a physician specializing in internal medicine, endocrinology, and hospice care. He is an internationally recognized educator and thought leader on the microbiome as it relates to health, disease, and food systems.     CURED Nutrition Get 15% off your CURED Nutrition order with the code WELLNESSFORCE It's taken me over a year to find the right hemp and CBD company to introduce to the Wellness Force Community and I could not be more thrilled that it's CURED Nutrition! CURED Nutrition is a movement inspired by nature and grounded in a shared desire to leave a lasting impression on you, our community, and this world. Together, they're a collective of heart-centered human beings who are inviting you – the conscious creatives, dreamers, and healers – to join their family. Learn how CURED hemp and CBD products can enhance your daily wellness routine. Try Cured Today They're Colorado-based organically grown hemp products that have been engineered to transform your approach toward an elevated life. Tap into your inherent potential – your greatest mind-body alignment – and nourish it with the supplements you were designed to thrive on. A greater existence is waiting.   More Top Episodes 226 Paul Chek: The Revolution Is Coming (3 Part Series) 131 Drew Manning: Emotional Fitness 129 Gretchen Rubin: The Four Tendencies  183 Dr. Kyra Bobinet: Brain Science 196 Aubrey Marcus: Own The Day 103 Robb Wolf: Wired To Eat Best of The Best: The Top 10 Guests From over 200 Shows Get More Wellness In Your Life (for free) Join the Wellness Force Community on Facebook Get the M21 Calm Mind + Immunity Boosting Guide [spacer height="20px" id="2"]