Podcasts about tukey

I sit down with my Son Malachi and talk about his vary first hunt with dad and its the youth Turkey season.https://www.tuogear.com/ use code: FF-GRB2MSUY for 25% offhttps://www.phelpsgamecalls.com/ use code: ridgeline10 for 10% off https://www.crazyelkcompany.com/ use code: ridgeline20 for 20% offhttps://ghostscream.com/ use code: ghost20 for 20% offhttps://www.theduckcamp.net/ Book your waterfowl hunts now tell them Ridgeline Hunting sent youBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-ridgeline-hunting-podcast--5476683/support.

Tukey supplies for Thanksgiving, autonomous sprayers claim significant reduction in herbicide use, water flow standards for two north state rivers, more estimates on hurricane crop damage in the south.

Steed and Jrad are trying out some new segments in this weeks Chubstep but before they get to  how carrying a baby causes way too many random people to talk to you, Steed getting rear ended again in his ‘Bonehead Move of the Week', the longest worst organized and most insane Olympic event ever…the 1904 Olympic Marathon in ‘Chubistory', Steeds new award winning segment ‘Kinda Not and Kinda Hot' talking about the Olympic controversies of Russian sabotage and getting removed for inappropriate behavior, Jrad's new segment ‘My Sob Story for Reality TV' where he turns a movie plot into a personal sob story so that he can be relatable if he goes on a reality TV dating show, and the viral Olympic shooter from Tukey.

Headlines: Palestinian hospital rocket misfire; Abbas cancels meeting with Biden; Hezbollah declares a ‘day of unprecedented rage'; Israel warns citizens in Tukey to leave; Biden in Israel; the riskiest trip of his presidency. Interview with Dexter Van Zile, managing editor of the Middle East Forum publication Focus on Western Islamism.  See omnystudio.com/listener for privacy information.

“T” is for Tukey, Richard Ellery (1918-1979). Civic leader. Richard Tukey helped transform the Upcountry's economy by international recruitment, by expansion away from textiles, and by taking a decidedly global outlook on economic development.

With Turkey's weekend election inconclusive, the nation appears headed for a runoff. In Thailand, analyists say the Move Forward Party's win is a strong rebuke of military-backed rule. And Pickleball is the fastest-growing sport in the United States, but not everyone loves it.

More than 22,000 people have been killed by the devastating earthquakes that ravaged Turkey and Syria this week and the death toll keeps rising. There is a desperate need for humanitarian and medical assistance. You can help by donating to Doctors Without Borders (DoctorsWithoutBorders.org) or UNICEF (UNICEFusa.org).  Biden does some effective political theater of his own, by saying some Republicans wanted to cut Social Security. On the spot, Biden got all the Republicans to stand and cheer that they do not want to gut Social Security or Medicare. Well done sir.  And, AR-15 lapel pins accompanied American flag pins on Republican members of Congress at the State of the Union this week.  And, do we need to talk about that balloon? Senator John Fetterman was admitted to the hospital after feeling light-headed during a Senate retreat on Wednesday. Tests found that Fetterman did not have another stroke, and were running additional tests.  PA Democrats swept the three special elections, giving them the outright majority in the state assembly.   The Zombie Fungus continues to spread as the voices of those infected by right-wing media and extremist politics flood a local Telford, PA council meeting. The Council wants to slash the public library's budget and hand it over to the police. The police already receive half of the town's resources. And, can you guess why they want to cut funds to the library? I bet you can.  Walter Masterson of political satire group The Good Liars, showed up at the Central Bucks School Board meeting as the district continues to be a laboratory for extremist politics.  And the Pennridge High School principal was arrested for a DUI this past weekend.

A massive earthquake devastates Tukey and Syria, killing more than a thousand people so far. Also, new details on Chinese surveillance balloon shot down by U.S. military. Plus, new evacuations ordered as concerns mount in Northeastern Ohio over a potential explosion at the site of a train derailment. And, a recap of the star-studded Grammy's last night, with heavy hitters like Beyoncé, Adele, Taylor Swift, Harry Styles, and more in attendance. 

A massive earthquake devastates Tukey and Syria, killing more than a thousand people so far. Also, new details on Chinese surveillance balloon shot down by U.S. military. Plus, a dangerous close call at a Texas airport is now under federal investigation. And, the story of a woman with a transplanted uterus, who has now given birth to two sons. 

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.16.512413v1?rss=1 Authors: Telles, B. d. S., Rebelato, H. J., Esquisatto, M. A., Catisti, R. Abstract: Poor nutrition during pregnancy causes permanent metabolic and/or structural adaptation in offspring. The adrenal gland produces various steroid hormones during pregnancy. Thus, this study aimed to evaluate the influence of diet during pregnancy on the adrenal glands of Wistar rats. For this, 10-week-old pregnant Wistar rats (p, n=15) and non-pregnant rats (np, n=15) were divided into three groups and received a normoproteic control diet (C, 17% casein, n=5), isocaloric low-protein diet (PR, 6% casein, n=5), or 50% calorie restriction (CR, 50% of the diet consumed by group C), over a period of 21 days. On the 21st day of gestation (21dG, p groups) or on the 21st day of diet (np groups), after anesthetic deepening, the right adrenal gland was collected, weighed (total mass), and prepared for inclusion in Paraplast for histomorphometric and immunohistochemical analysis (Ki-67, glucocorticoid receptors (GR), and mineralocorticoid receptor (MR)) in the different areas of the gland. Data, expressed as the mean and SD, were evaluated by one-way analysis of variance with Tukey's post-test (p less than 0.05). CR in pregnancy increased the amount of GR, MR, and Ki-67 receptors in the adrenal gland. The npRC group showed highest GR staining compared to the animals that received a normal diet. Protein restriction in pregnancy decreases adrenal MR. The results allowed us to conclude that even without altering the weight of the adrenal glands, the pRC group suffered the most from stress during the study, suggesting that CR associated with pregnancy can cause morphofunctional changes in the adrenal glands. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Front Porch Republic's Jeff Bilbro shares how a major satirical site that persuades people has now been raised to a new level and the benefits of being in a place where it's impossible to stay anonymous. Mission Network News' Ruth Kramer unpacks why in Iran the Word of God is viewed as contraband and equipping the church in Tukey for struggles to come. Click here for today's show notes

Updates on CMS' Star Ratings and the impact that they will have on health plans and members...

1559-65: The Knight's Hospitaller's continued piracy and disruption of Ottoman trade lanes proves the sultan to finally respond Song: Violence by A Day to Remember - Common Courtesy (had to change this week's music because it didn't sound the way I wanted)

Happy Thanksgiving everyone! Gleenobly and Russ talk about a turkey named Tom, some fun Thanksgiving memories, and a startled turkey... enjoy! Gobble... Gobble...

Chef's Brandon and KC discuss current events and issues surrounding the culinary industry. Apple Podcast Link: https://apple.co/3n4KkvV Spotify Podcast Link: https://spoti.fi/2Z8bsCc Tiktok @chefauthorized | YouTube @ BrandonDearden Tiktok @chefsalty | YouTube @ KCGonzalez This week we discuss: Tukey, Sides, Tips and Tricks, other proteins to think about and perfect temp to always get a moist turkey.

I follow through on last week's threat of choosing the plant species named after a venereal disease as the Plant of the Week (Lobelia siphilitica) and Bunny Williams and I chat about gardens, garden design, HER garden, which is spectacular, and her garden book, On Garden Style at 5:55. The Play List includes info on spider mites, flagging annuals, and the possibility of an organic lawn.

CyprusScene brings a review by the Young Turkish Cypriot group of the 2021 Peace and Freedom Day celebration...Click below to see many photos which explain why it was necessary for Tukey to mount a Peace Intervention operation to stop the ethnic cleansing of Turkish Cypriots by Greek and Greek Cypriot forces. This episode is also available as a blog post: https://cyprusscene.com/2021/07/21/young-turkish-cypriots-celebrate-peace-and-freedom-day-in-lefkosa/ CyprusScene Podcasts can be found on the following apps Anchor, Google Podcasts, Spotify, RadioPublic, PocketCasts, Breaker, Castbox, Apple Itunes

Sunflower peptide as 'template' for potential analgesic Medical University of Vienna (Austria), June 28, 2021 A naturally occurring peptide in sunflower seeds was synthetically optimised and has now been identified as a potential drug for treating abdominal pain or inflammation (in the gastrointestinal tract, abdominal area and/or internal organs). That is the finding of an international study led by Christian Gruber from MedUni Vienna's Institute of Pharmacology (Center for Physiology and Pharmacology), which was conducted jointly with the University of Queensland and Flinders University in Australia and has now been published. The scientific aim of the study is to find analgesics that are only active in the periphery and do not cross the blood-brain barrier, as an alternative to commonly used synthetic opioids. Gruber explains the background: "Morphine was one of the first plant-based medicines and was isolated from the dried latex of poppies more than 200 years ago. It binds to opioid receptors in the brain and is still regarded as the main pillar of pain therapy. However, there is a high risk of opioid addiction, and an overdose - as a result of this strong dependency - inhibits the breathing centre in the brain, which can result in respiratory depression and, in the worst case, in death." For this reason, researchers throughout the world are trying to make analgesics safer and to find active drug molecules that do not have the typical opioid side-effects.  Sunflower extracts were to some extent used in traditional medicine for their anti-inflammatory and analgesic properties. In the current study, the scientists from Austria and Australia, primarily PhD student Edin Muratspahi?, isolated the plant molecule that may be responsible for this effect. Medicinal chemistry methods were then used to optimise the so-called sunflower trypsin inhibitor-1 (SFTI-1), one of the smallest naturally occurring cyclic peptides, by 'grafting' an endogenous opioid peptide into its scaffold.  A total of 19 peptides were chemically synthesized based on the original SFTI-1 blueprint and pharmacologically tested. "One of these variants turned out to be our lead candidate for as potential innovative analgesic molecule, especially for pain in the gastrointestinal tract or in the peripheral organs. This peptide is extremely stable, highly potent and its action is restricted to the body's periphery. Its use is therefore expected to produce fewer of the typical side-effects associated with opioids," point out Gruber and Muratspahi?.  The mode-of-action of the peptide is via the so-called kappa opioid receptor; this cellular protein is a drug target for pain relief, but is often associated with mood disorders and depression. The sunflower peptide does not act in the brain, hence there is much less risk of dependency or addiction. Furthermore, it selectively activates only the molecular signalling pathway that influences pain transmission but does not cause the typical opioid side-effects. The data of the animal model in the current study are very promising: the scientists see great potential for using this peptide in the future to develop a safe medication - which could be administered orally in tablet form - to treat pain in the gastrointestinal tract, and this drug could potentially also be used for related painful conditions, e.g. for inflammatory bowel disease.  Using Nature's blueprint The research of this MedUni Vienna laboratory led by Christian Gruber exploits the concept of using Nature's blueprint to develop optimised drugs. "We are searching through large databases containing genetic information of plants and animals, decoding new types of peptide molecules and studying their structure, with a view to testing them pharmacologically on enzymes or membrane receptors and ultimately utilizing them in the disease model," explains Gruber. Finally, potential drug candidates are chemically synthesised in a slightly modified form based on the natural blueprint, to obtain optimised pharmacological properties.   Study associates organic food intake in childhood with better cognitive development Analysis of multiple prenatal and childhood environmental risk factors suggests that poor nutrition, house crowding and indoor air pollution are associated with poorer cognitive function Barcelona Institute for Global Health (Spain), July 1, 2021 A study analysing the association between a wide variety of prenatal and childhood exposures and neuropsychological development in school-age children has found that organic food intake is associated with better scores on tests of fluid intelligence (ability to solve novel reasoning problems) and working memory (ability of the brain to retain new information while it is needed in the short term). The study, published in Environmental Pollution, was conceived and designed by researchers at the Barcelona Institute for Global Health (ISGlobal)--a centre supported by the "la Caixa" Foundation--and the Pere Virgili Health Research Institute (IISPV-CERCA).  The explanation for this association may be that "healthy diets, including organic diets, are richer than fast food diets in nutrients necessary for the brain, such as fatty acids, vitamins and antioxidants, which together may enhance cognitive function in childhood," commented lead author Jordi Júlvez, a researcher at IISPV-CERCA who works closely with ISGlobal.  The study also found that fast food intake, house crowding and environmental tobacco smoke during childhood were associated with lower fluid intelligence scores. In addition, exposure to fine particulate matter (PM2.5) indoors was associated with lower working memory scores.  The study, titled "Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries", used data on 1,298 children aged 6-11 years from six European country-specific birth cohorts (United Kingdom, France, Spain, Greece, Lithuania and Norway). The researchers looked at 87 environmental factors the children were exposed to in utero (air pollution, traffic, noise, various chemicals and lifestyle factors) and another 122 factors they were exposed to during childhood. A Pioneering Study The aim of the study was to analyse the influence of these exposures on the development and maturation of the human brain, since during childhood the brain is not yet fully developed for efficient defence against environmental chemicals and is particularly sensitive to toxicity, even at low levels that do not necessarily pose a risk to a healthy mature brain.  The originality of the study lies in its use of an exposome approach, i.e. the fact that it takes into account the totality of exposures rather than focusing on a single one. This approach aims to achieve a better understanding of the complexity of multiple environmental exposures and their simultaneous effect on children's neurodevelopment.  Another strength of the study, which analyses cohorts from six European countries, is its diversity, although this factor also poses the additional challenge of cultural differences, which can influence exposure levels and cognitive outcomes. Notable Associations The study found that the main determinants of fluid intelligence and working memory in children are organic diet, fast food diet, crowdedness of the family home, indoor air pollution and tobacco smoke. To date, there has been little research on the relationship between type of diet and cognitive function, but fast food intake has been associated with lower academic development success and some studies have also reported positive associations between organic diets and executive function scores. "In our study," explained Júlvez, "we found better scores in fluid intelligence and working memory with higher organic food intake and lower fast food intake."  In contrast, exposure to tobacco smoke and indoor PM2.5 during childhood may negatively affect cognitive function by enhancing pro-inflammatory reactions in the brain. Still, according to Júlvez, it is worth bearing in mind that "the number of people living together in a home is often an indicator of the family's economic status, and that contexts of poverty favour less healthy lifestyles, which in turn may affect children's cognitive test scores".  Some Surprising Findings  The study also found some unexpected associations, which could be explained by confounding and reverse causality. For example, a positive association was found between childhood exposure to perfluorooctane sulfonic acid (PFOS) and cognitive function, even though PFOS is considered an endocrine disruptor that may alter thyroid function and negatively influence cognitive development.  The study forms part of the large European project Human Early-Life Exposome (HELIX), as does another recent paper that used the same exposome and the same participants but looked at symptoms of attention deficit hyperactivity disorder (ADHD) and childhood behavioural problems. "We observed that several prenatal environmental pollutants (indoor air pollution and tobacco smoke) and lifestyle habits during childhood (diet, sleep and family social capital) were associated with behavioural problems in children," explained Martine Vrijheid, last author of the study and head of ISGlobal's Childhood and Environment programme. "One of the strengths of this study on cognition and the earlier study on behavioural problems is that we systematically analysed a much wider range of exposure biomarkers in blood and urine to determine the internal levels in the model and that we analysed both prenatal and childhood exposure variables," concluded Vrijheid.     Extract of mulberry leaves partially restores the composition of intestinal microbiota and strengthens liver glycogen fragility in diabetic rats Macau University of Science and Technology (China), June 28, 2021 According to news reporting out of Macau, People's Republic of China, research stated, “Mulberry leaf as a traditional Chinese medicine is able to treat obesity, diabetes, and dyslipidemia. It is well known that diabetes leads to intestinal microbiota dysbiosis.” Our news journalists obtained a quote from the research from the Macau University of Science and Technology, “It is also recently discovered that liver glycogen structure is impaired in diabetic animals. Since mulberry leaves are able to improve the diabetic conditions through reducing blood glucose level, it would be interesting to investigate whether they have any positive effects on intestinal microbiota and liver glycogen structure. In this study, we first determined the bioactive components of ethanol extract of mulberry leaves via high-performance liquid chromatography (HPLC) and liquid chromatography/mass spectrometry (LC/MS). Murine animal models were divided into three groups, normal Sprague-Dawley (SD) rats, high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic rats, and HFD/STZ-induced rats administered with ethanol extract of mulberry leaves (200 mg/kg/day). Composition of intestinal microbiota was analyzed via metagenomics by sequencing the V3-V4 region of 16S rDNAs. Liver glycogen structure was characterized through size exclusion chromatography (SEC). Both Student's t-test and Tukey's test were used for statistical analysis. A group of type 2 diabetic rat models were successfully established. Intestinal microbiota analysis showed that ethanol extract of mulberry leaves could partially change intestinal microbiota back to normal conditions. In addition, liver glycogen was restored from fragile state to stable state through administration of ethanol extract of mulberry leaves. This study confirms that the ethanol extract of mulberry leaves (MLE) ameliorates intestinal microbiota dysbiosis and strengthens liver glycogen fragility in diabetic rats.” According to the news editors, the research concluded: “These finding can be helpful in discovering the novel therapeutic targets with the help of further investigations.”     Supplemental antioxidants may reduce exacerbations in cystic fibrosis     University of Colorado, July 2, 2021 An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with cystic fibrosis(CF), according to new research published online iin the American Journal of Respiratory and Critical Care Medicine. In "Effects of an Antioxidant-Enriched Multivitamin in Cystic Fibrosis: Randomized, Controlled, Multicenter Trial," Scott D. Sagel, MD, PhD, a professor of pediatrics at Children's Hospital Colorado and director of the University of Colorado Cystic Fibrosis Center, and coauthors report a 50 percent reduced risk of time to the first exacerbation requiring antibiotics in those receiving the supplemental antioxidants. During the 16-week study of 73 patients (36 received supplemental antioxidants), 53 percent of the antioxidant-treated group experienced 28 exacerbations, compared to 68 percent of the control group who experienced 39 exacerbations. The researchers also found that supplemental antioxidants increased circulating antioxidant concentrations of beta-carotene, coenzyme Q10, gamma-tocopherol (a form of vitamin E) and lutein and transiently decreased inflammation (at 4 weeks, but not 16 weeks) as measured by two blood-based biomarkers of inflammation, calprotectin and myeloperoxidase (MPO). People with CF typically experience chronic bacterial infections, which lead to inflammation and the release of "vast amounts of reactive oxygen species in the airways," the authors wrote. Normally, they added, the body would marshal an antioxidant defense to neutralize this oxidant stress, but CF is characterized by dietary antioxidant deficiencies. This contributes to an oxidant-antioxidant imbalance and more inflammation, which leads to lung damage and a progressive loss of lung function. "Improving antioxidant status in CF is an important clinical goal and may have a positive effect on health," Dr. Sagel said. "Oral antioxidant formulations had been tested in CF with mixed results. However, there had not been a well-designed randomized controlled trial of an antioxidant 'cocktail' that included multiple antioxidants in a single formulation." This phase 2 trial, conducted at 15 CF centers affiliated with the CF Foundation Therapeutics Development Network, enrolled patients who were 10 years and older (average age 22 years), with pancreatic insufficiency, which causes malabsorption of antioxidants. Participants had an FEV1, the measure of how much air can be forcefully exhaled in one second, between 40 and 100 percent of what would be predicted, based on age, gender, height and a range of other characteristics. Patients in the control group received a multivitamin without antioxidant enrichment. The two groups tolerated their vitamins equally well, and there were no differences in adverse events between the two groups. The study did not meet its primary endpoint: change in sputum MPO concentration over 16 weeks. The authors chose sputum MPO "rather than another marker of airway inflammation such as neutrophil elastase because MPO generates reactive oxidant species as part of its function in innate host defense mechanisms, and is considered by many a marker of oxidative stress." "While the antioxidant supplement did not appear to exert sustained anti-inflammatory effects, we believe its effect on time to first pulmonary exacerbation was significant and clinically meaningful," Dr. Sagel said, adding that the improvement in antioxidant status alone may justify its use. "Developing safe and effective anti-inflammatory treatments remains a key priority of the CF community."   Maternal diets rich in Omega-3 fatty acids may protect offspring from breast cancer Marshall University School of Medicine, June 28, 2021 According to researchers at Marshall University, a maternal diet rich in Omega-3 fatty acids protects from breast cancer development in offspring. In a new studyrecently published by Frontiers in Cell and Developmental Biology, researchers noted a significant difference in mice from mothers that were fed a diet rich in canola oil, compared with mothers fed a diet rich in corn oil. A maternal Omega 3-rich diet affected genome-wide epigenetic landscape changes in offspring and potentially modulated gene expression patterns. Dr. Ata Abbas, a former postdoctoral research fellow in Marshall's Department of Biological Sciences, headed a research team under the leadership of Dr. Philippe Georgel in the College of Science. Research was done in the Cell Differentiation and Development Center at Marshall as part of a collaborative effort with the Joan C. Edwards School of Medicine's Department of Biochemistry and Microbiology, under the leadership of Dr. W. Elaine Hardman. Researchers noticed a three-week delay in mortality in mice whose mothers were fed canola oil versus corn oil. The early delay in mortality was significantly different, but the ultimate overall survival rate was not. Eventually, all the mice developed tumors, but the ones fed canola oil had tumors that were slower-growing and smaller than the mice fed corn oil. Translated to human time scale, the duration of the protective effect linked to the maternal diet would be equivalent to several months (Sengupta et al., 2016). This study is among a body of work done by Marshall University scientists and others looking at the link between Omega-3 fatty acids and reduced incidence of various types of cancer including, but not restricted to, Chronic Lymphocytic Leukemia and Diffuse Large B-Cell Lymphoma. "The issue of parental diet and inter-generational transmission has become an important field of research; however, the mode of action often remains partially elusive," said Georgel, a professor in the Department of Biological Sciences at Marshall. "The MU research group focused on 'epigenetic' aspects of trans-generational transmission to explain the reported role of Omega-3 fatty acids. Epigenetics involves changes in gene expression which are not linked to changes in genetic sequences. These results have the potential to promote the design of simple changes in diet which would allow for reduced onset of various types of cancer, not only for the individuals using that diet but also for their offspring."     Compounds found in green tea and wine may block formation of toxic metabolites Tel Aviv University (Israel), July 2, 2021 A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine. Most people with inherited metabolic disorders are born with a defective gene that results in a critical enzyme deficiency. In the absence of a cure, many patients with inborn congenital metabolic disorders must adhere to a strict and demanding diet their entire lives. This new research finds that certain compounds found naturally in green tea and red wine may block the formation of toxic metabolites. The research was led by Prof. Ehud Gazit of TAU's Faculty of Life Sciences and his doctoral student Shira Shaham-Niv. It was published in the Nature group journal Communications Chemistry. The researchers considered two compounds: (1) epigallocatechin gallate, known as EGCG, found naturally in green tea, which has attracted attention within the medical community for its potential health benefits; and (2) tannic acid, found in red wine, which is known to prevent the formation of toxic amyloid structures that cause neurodegenerative disorders such as Alzheimer's and Parkinson's disease. "In the case of inborn congenital metabolic diseases, the body does not produce a vital metabolic enzyme," Shaham-Niv said. "As a result, metabolites -- substances that are, among other things, the building blocks of DNA and proteins -- accumulate in the body. Such uncontrolled accumulation is toxic and can cause severe developmental and mental disorders. "Our new study demonstrates once again the ability of nature to produce the best candidate of drugs to treat some of the worst human maladies." Collectively, this group of disorders constitutes a significant portion of pediatric genetic diseases. The disease phenylketonuria (PKU), which produces the aggregation of the metabolite phenylalanine, is one common inborn metabolic disease. Infants with PKU must adhere to a strict diet free of phenylalanine for the rest of their lives. If they don't, they may face severe debilitating developmental problems. "But this is an incredibly difficult task, since phenylalanine is found in most of the food products that we consume," Shaham-Niv said. "The avoidance of certain substances is the only way to prevent the debilitating long-term effects of inborn congenital metabolic disorders. We hope that our new approach will facilitate the development of new drugs to treat these disorders." The new research is based on two previous studies conducted at Prof. Gazit's TAU laboratory. In the first study, phenylalanine was shown to be capable of self-assembly and of forming amyloid structures like those seen in Alzheimer's, Parkinson's and other neurodegenerative diseases. In the second study, by Shaham-Niv, other metabolites that accumulate in other inborn congenital metabolic diseases were also shown to undergo self-assembly processes and form toxic amyloid aggregates. "Both studies led to an overhaul in the research community's understanding of metabolic diseases," Shaham-Niv said. "In our new study, we examined whether the molecules identified in past studies on Alzheimer's disease and other amyloid diseases, which are known to inhibit the formation of amyloid aggregates, could also help counteract the amyloid formation process of metabolites in metabolic diseases." The new research focused on EGCG and tannic acid using test tubes and culture cell systems. The two substances were tested on three metabolites related to three innate metabolic diseases: adenine, cumulative tyrosine and phenylalanine. The results were promising. Both tannic acid and EGCG were effective in blocking the formation of toxic amyloid structures. The researchers also used computer simulations to verify the mechanism driving the compounds. "We are entering a new era of understanding the role and the importance of metabolites in various diseases, including metabolic diseases, neurodegenerative diseases and even cancer," Shaham-Niv concluded. "The tools we have developed are ground-breaking and have tremendous potential to help a wide range of patients in the future."       People with fibromyalgia are substituting CBD for opioids to manage pain University of Michigan, June 24, 2021 Fibromyalgia is one of many chronic pain conditions that remains stubbornly difficult to treat.  As the ravages of the opioid epidemic lead many to avoid these powerful painkillers, a significant number of people with fibromyalgia are finding an effective replacement in CBD-containing products, finds a new Michigan Medicine study.  CBD, short for cannabidiol, is the second most common cannabinoid in the cannabis plant, and has been marketed for everything from mood stabilization to pain relief, without the intoxicating effects produced by the most common cannabinoid, THC. THC, which stands for delta-9-tetrahydrocannabinol, is the ingredient in marijuana that causes people to feel high. The cannabis industry has exploded, aided by the legalization of medical and recreational marijuana in states around the United States and the removal of hemp-derived CBD from Schedule 1 status--reserved for drugs with no currently accepted medical use and a high potential for abuse--at the federal level.  Previous research shows that some people substitute medical cannabis (often with high concentrations of THC) for opioids and other pain medications, reporting that cannabis provides better pain relief and fewer side effects. However, there is far less data on CBD use. "CBD is less harmful than THC, as it is non-intoxicating and has less potential for abuse," said Kevin Boehnke, Ph.D., a research investigator in the Department of Anesthesiology and the Chronic Pain and Fatigue Research Center. "If people can find the same relief without THC's side effects, CBD may represent a useful as a harm reduction strategy." Boehnke and his team surveyed people with fibromyalgia about their use of CBD for treatment of chronic pain.  "Fibromyalgia is not easy to treat, often involving several medications with significant side effects and modest benefits," Boehnke explained. "Further, many alternative therapies, like acupuncture and massage, are not covered by insurance." For this study, the team focused on 878 people with fibromyalgia who said they used CBD to get more insight into how they used CBD products.  The U-M team found that more than 70% of people with fibromyalgia who used CBD substituted CBD for opioids or other pain medications. Of these participants, many reported that they either decreased use or stopped taking opioids and other pain medications as a result.  "I was not expecting that level of substitution," said Boehnke, noting that the rate is quite similar to the substitution rate reported in the medical cannabis literature. People who said they used CBD products that also contained THC had higher odds of substitution and reported greater symptom relief. Yet the finding that products containing only CBD also provided pain relief and were substituted for pain medications is promising and merits future study, noted Boehnke.  The team noted that much of the widespread use of CBD is occurring without physician guidance and in the absence of relevant clinical trials. "Even with that lack of evidence, people are using CBD, substituting it for medication and doing so saying it's less harmful and more effective," he said.  Boehnke stressed the need for more controlled research into how CBD may provide these benefits, as well as whether these benefits may be due to the placebo effect.  Clinically, opening up lines of discussion around CBD use for chronic pain is imperative, said Boehnke, for medication safety reasons as well as for "enhancing the therapeutic alliance and improving patient care."

Dominik shares the story and principles behind Vega and Vega-Lite, and explains how visualization and machine learning help each other. --- Dominik is a co-author of Vega-Lite, a high-level visualization grammar for building interactive plots. He's also a professor at the Human-Computer Interaction Institute Institute at Carnegie Mellon University and an ML researcher at Apple. Connect with Dominik Twitter: https://twitter.com/domoritz GitHub: https://github.com/domoritz Personal website: https://www.domoritz.de/ --- 0:00 Sneak peek, intro 1:15 What is Vega-Lite? 5:39 The grammar of graphics 9:00 Using visualizations creatively 11:36 Vega vs Vega-Lite 16:03 ggplot2 and machine learning 18:39 Voyager and the challenges of scale 24:54 Model explainability and visualizations 31:24 Underrated topics: constraints and visualization theory 34:38 The challenge of metrics in deployment 36:54 In between aggregate statistics and individual examples Links Discussed Vega-Lite: https://vega.github.io/vega-lite/ Data analysis and statistics: an expository overview (Tukey and Wilk, 1966): https://dl.acm.org/doi/10.1145/1464291.1464366 Slope chart / slope graph: https://vega.github.io/vega-lite/examples/line_slope.html Voyager: https://github.com/vega/voyager Draco: https://github.com/uwdata/draco Check out the transcription and discover more awesome ML projects: http://wandb.me/domink-moritz --- Get our podcast on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts​ Spotify: http://wandb.me/spotify​ Google: http://wandb.me/google-podcasts​ YouTube: http://wandb.me/youtube​ Soundcloud: http://wandb.me/soundcloud --- Join our community of ML practitioners where we host AMA's, share interesting projects and meet other people working in Deep Learning: http://wandb.me/slack​ Our gallery features curated machine learning reports by researchers exploring deep learning techniques, Kagglers showcasing winning models, and industry leaders sharing best practices: https://wandb.ai/gallery

It's an AWIPOD Holiday special! Erica, Steve and Brent watch a interesting Survivor Series match! We hope all our friends have a safe and good Thanksgiving! We thank everyone for your support!

The Bit: Bryan and Hoadley review Chuck E. Cheese pizza. The Show: Bryan and Hoadley discuss Only Fans pages and the marketing that goes into a successful campaign, Bryan tells Hoadley about his trashy television habits and revisits the time his date brought Thanksgiving dinner to the bedroom. This and so much more...on episode 17 of The Commercial Break!

Finally, a way to read comics in class without your teacher complaining! Real life scientists are producing educational comics to teach cool science stuff. And they're FREE! Check them out, they have some pretty good explanations for a bunch of different topics.The FDA has recognised the ability of video games to help with therapy and greenlit a game for treating ADHD suffers. I can't wait for a game to help you deal with idiots, but we'll get there one day.Where did Matt Mercer's Vox Machina come from? Now you can read both of the first two seasons of the Critical Role prequels in a hardback omnibus. Wait, didn't we already do comics this week? Oops. Anyway, watch Critical Role. It's really good.This week, Professor took to the skies in Sky Rogue and DJ set us up the bomb in Valorant.Real Life Scientists making comics- https://www.sciencenews.org/article/real-life-scientists-inspire-comic-book-superheroes-science-literacy- https://www.jkxcomics.com/- https://static1.squarespace.com/static/59ab7c15e4fcb5c602a09465/t/5a08e052e2c483d6cb8cf769/1510531187492/JKXComics_EBV+and+the+Replication+Dance.pdfA video game for kids with ADHD is greenlit by the FDA- https://www.statnews.com/2020/06/15/fda-akili-adhd-endeavorrx/Dark Horse to Release 'Critical Role' Hardcover Omnibus- https://www.hollywoodreporter.com/heat-vision/dark-horse-release-critical-role-hardcover-omnibus-1296484Games PlayedProfessor– Sky Rogue - https://store.steampowered.com/app/381020/Sky_Rogue/Rating: 3.5/5DJ– Valorant – https://playvalorant.com/en-us/Rating: 3/5Other topics discussedThe Last of Us Part 2 game review : Not as Good as It Thinks It Is- https://www.thewrap.com/the-last-of-us-part-2-review-not-as-good-as-it-thinks-it-is-ellie-naughty-dog/Naughty Dog's Neil Druckmann calls out journalist Jason Schreier for Anne Frank joke- https://www.ginx.tv/en/video-games/naughty-dog-s-neil-druckmann-calls-out-journalist-jason-schrier-for-anne-frank-jokeG.I. Joe - Give Him The Stick : Parody of G.I. Joe's Public Service Announcements created by Fensler films- https://www.youtube.com/watch?v=DXFdPTaCtkcVictoria's sudden spike in coronavirus cases could result in localised lockdowns- https://7news.com.au/lifestyle/health-wellbeing/victorias-sudden-spike-in-coronavirus-cases-could-result-in-localised-lockdowns-c-1113679Epstein–Barr virus (EBV) (formally called Human gammaherpesvirus 4, is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.)- https://en.wikipedia.org/wiki/Epstein%E2%80%93Barr_virusOnce Upon a Time….Life (French animated series which tells the story of the human body for children.)- https://en.wikipedia.org/wiki/Once_Upon_a_Time..._LifeCells at Work! (Japanese manga series written and illustrated by Akane Shimizu. It features the anthropomorphized cells of a human body, with the two main protagonists being a red blood cell and a white blood cell she frequently encounters.)- https://en.wikipedia.org/wiki/Cells_at_Work!Cells at Work! CODE BLACK (spin-off written by Shigemitsu Harada, illustrated by Ikuta Hatsuya, and supervised by the author of the original, Akane Shimizu. Similar to the original, the series is set in a world of anthropomorphic cells working in a body. It follows a the life of a rookie Erythrocyte, AA2153, and a Neutrophil, U-1196, as they work in a poorly maintained, middle-aged body burdened by issues such as stress, smoking, drinking and the like, causing complications in the cells' work and living environment.)- https://cellsatwork.fandom.com/wiki/Cells_at_Work!_CODE_BLACKInside Ralphie (Magic School Bus episode) (Third episode of Season 1 of the animated children's series The Magic School Bus. While Ralphie hosts a TV broadcast from his sickbed, his classmates seek to discover the cause of his illness.)- https://magicschoolbus.fandom.com/wiki/Inside_RalphieFor Lunch (Magic School Bus episode) (Second episode of season one of the animated children's series The Magic School Bus. Ms. Frizzle's students explore Arnold's digestive system after he accidentally swallows his miniaturized classmates.)- https://magicschoolbus.fandom.com/wiki/For_LunchFood and Drug Administration ((FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counterpharmaceutical drugs (medications), vaccines,biopharmaceuticals,blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, animal foods & feed and veterinary products.)- https://en.wikipedia.org/wiki/Food_and_Drug_AdministrationRitalin (Methylphenidate, sold under the trade name Ritalin among others, is a stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is a first line medication for ADHD. It may be taken by mouth or applied to the skin.)- https://en.wikipedia.org/wiki/MethylphenidateTali Health (Tali Health creates game based programs to improve attention in children. TALi TRAIN is a clinically validated digital training and treatment program that addresses the world’s leading reported early childhood issue-attention difficulties, a key feature in conditions including ADHD and ASD (Autism Spectrum Disorder).)- https://talihealth.com.au/Michele Assarasakorn (comic artist | colorist on ISOLA / Gotham Academy/ Critical Role)Twitter : https://twitter.com/msassykInstagram : https://www.instagram.com/msassyk/Critical Role Wiki (A Place Documenting the Current History of Exandria)- https://criticalrole.fandom.com/wiki/Critical_Role_WikiThe World of RWBY: The Official Companion (RWBY lore book)- https://www.amazon.com/World-RWBY-Official-Companion/dp/1974704386Critical Role: Vox Machina Origins Library Edition: Series I & II Collection at Amazon-https://www.amazon.com/Critical-Role-Machina-Origins-Collection/dp/1506721737Ace Combat (Ace Combat is a hybrid arcade-style flight action video game franchise mainly developed by Bandai Namco Studios and published by Bandai Namco Entertainment.)- https://en.wikipedia.org/wiki/Ace_CombatLUFTRAUSERS (shoot 'em up video game developed by Netherlands-based indie developer studio Vlambeer and published by Devolver Digital for Microsoft Windows, OS X,Linux, PlayStation 3 and PlayStation Vita.)- https://store.steampowered.com/app/233150/LUFTRAUSERS/Guns of Icarus (Guns of Icarus Online is the original PvP steampunk airship combat game that laid the groundwork for the expanded Guns of Icarus experience, Guns of Icarus Alliance.)- https://store.steampowered.com/app/209080/Guns_of_Icarus_Online/PS5 Reveal Event & Every Next Gen Game announced- https://www.gamespot.com/articles/ps5-reveal-event-every-nextgen-game-announced-by-s/1100-6478266/Space Shuttle Challenger disaster (The Space Shuttle Challenger disaster was a fatal incident in the United States space program that occurred on Tuesday, January 28, 1986, when the Space Shuttle Challenger (OV-099) broke apart 73 seconds into its flight, killing all seven crew members aboard. The failure was caused by the failure of O-ring seals used in the joint that were not designed to handle the unusually cold conditions that existed at this launch.)- https://en.wikipedia.org/wiki/Space_Shuttle_Challenger_disasterSpace Shuttle Columbia disaster (The Space Shuttle Columbia disaster was a fatal incident in the United States space program that occurred on February 1, 2003, when the Space Shuttle Columbia (OV-102) disintegrated as it reentered the atmosphere, killing all seven crew members. During the launch of STS-107,Columbia's 28th mission, a piece of foam insulation broke off from the Space Shuttle external tank and struck the left wing of the orbiter.)- https://en.wikipedia.org/wiki/Space_Shuttle_Columbia_disasterThe Slo Mo Guys - How a TV Works in Slow Motion- https://www.youtube.com/watch?v=3BJU2drrtCMWinnie the Pooh could be banned from Shanghai Disneyland as a result of an ongoing meme used to criticize China's leader-https://www.businessinsider.com/winnie-the-pooh-shanghai-disneyland-meme-2018-11?r=AU&IR=TObama & Xi Jinping as Tigger & Winnie The Pooh- https://pbs.twimg.com/media/DsXrZ-6UwAUHGRx?format=jpg&name=900x900Shout Outs11 June 2020 – Playstation 5 reveal - https://deadline.com/2020/06/sony-playstation-5-revealed-videogames-1202957140/Sony lifted the veil to reveal the PlayStation 5, the video game console it hopes will be a significant lure for consumers this holiday season. In a live-streamed video presentation lasting more than an hour, Sony Interactive Entertainment revealed new details for the PS5, including its design and lineup of new games. Rockstar Games’ Grand Theft Auto will be included for free, and there are two dozen other games heading to the platform. The unit’s two-tone design is a shift from previous versions and gives off distinct imperial stormtrooper vibes. PS5 will be available in both a standard model with an Ultra HD Blu-ray disc drive, and a digital model without a disc drive. One of the biggest series of all time, Grand Theft Auto, will be coming to PS5, with enhanced and expanded versions of Grand Theft Auto V and Grand Theft Auto Online to launch on PS5 in the second half of 2021.15 June 2020 – Rare stone ginger beer bottle from 1930s-era sells for record price - https://www.abc.net.au/news/2020-06-15/ginger-beer-bottle-sells-for-huge-price/12353574A rare ginger beer bottle from the 1930s, made for a Warwick soft drink company, has sold for a record price in Toowoomba. It has collectors encouraging people to check their sheds and old farm dumps for possible 'buried treasure'. The hammer fell at $17,500 for the stoneware Doneley and Butler bottle. The little green lip at the top is what set it apart from bottles worth a fraction of that price."These bottles are extremely rare, there have only been two or three found in perfect condition," said auctioneer Graham Lancaster."That colour combination of glazes makes it unique worldwide."He said the Warwick bottle set a record price locally, and quite possible a world-record, for an antique crown-seal soft drink bottle of its type.16 June 2020 – Christopher Nolan’s Batman Begins turns 15 - https://comicbook.com/movies/news/batman-begins-anniversary-the-dark-knight-christopher-nolan-christian-bale/As the '90s progressed, the image of Batman on the big screen began to descend into the realm of campiness previously seen in Adam West's take on the character back in the '60s TV series and movie, which started to sour audiences on the character entirely. After a variety of reports emerged about a new take on the character in the early '00s, fans were given Christopher Nolan's gritty and grounded origin story for the character in 2005, debuting Christian Bale as the Dark Knight. This new take on the character harkened back to some of the more grounded interpretations of the character, while adding just enough whimsy to remind audiences that this was still a comic book movie. Batman Begins went on to take in $371 million worldwide, a fraction of the figures that subsequent superhero movies would go on to earn, That film's success might not have been groundbreaking, but it set the stage for The Dark Knight and The Dark Knight Rises, with some audiences considering those films to be the best comic book films of all time, both of which earned major box office hauls and the former earning Heath Ledger a posthumous Oscar for his performance as the Joker.18 June 2020 – Dame Vera Lynn passes away at 103 - https://www.bbc.com/news/uk-53091856The singer was best known for performing hits such as We'll Meet Again to troops on the front line in countries including India and Egypt. Six weeks ago, ahead of the 75th anniversary of VE Day and during the height of the coronavirus pandemic, Dame Vera said simple acts of bravery and sacrifice still define our nation. A week later, she became the oldest artist to get a top 40 album in the UK, beating her own record when her greatest hits album re-entered the charts at number 30. Born in London's East Ham in 1917, Dame Vera's singing talent was discovered at a young age and by age 11 she had left school to pursue a full-time career as a dancer and singer. Lynn devoted much time and energy to charity work connected with ex-servicemen, disabled children and breast cancer. She was held in great affection by Second World War veterans and in 2000 was named the Briton who best exemplified the spirit of the 20th century. Paying tribute, Prime Minister Boris Johnson said the singer's "charm and magical voice entranced and uplifted our country in some of our darkest hours". "Her voice will live on to lift the hearts of generations to come," he said. She died at the age of 103 in Ditchling,East Sussex.19 June 2020 – Sir Ian Holm passes away at 88 - https://www.theguardian.com/film/2020/jun/19/ian-holm-dies-alien-chariots-of-fire-bilbo-bagginsSir Ian Holm, an acclaimed British actor whose long career included roles in Chariots of Fire and The Lord of the Rings has died. A star of stage and screen, Sir Ian won a Tony Award for best featured actor as Lenny in Harold Pinter's play The Homecoming in 1967. He won a British Academy Film Award and gained a supporting-actor Oscar nomination for portraying pioneering athletics coach Sam Mussabini in the hit 1982 film Chariots of Fire. His other well-known film roles include Ash in Alien, Father Vito Cornelius in The Fifth Element, Chef Skinner in Ratatouille, and Bilbo Baggins in The Lord of the Rings and The Hobbit film series. Sir Ian was knighted in 1998 for his services to drama. He died from Parkinson’s disease in London.Remembrances16 June 1804 – Johann Adam Hiller - https://en.wikipedia.org/wiki/Johann_Adam_HillerGerman composer,conductor and writer on music, regarded as the creator of the Singspiel, an early form of German opera. It is a form of German-language music drama, now regarded as a genre of opera. It is characterized by spoken dialogue, which is alternated with ensembles,songs, ballads, and arias which were often strophic, or folk-like. Singspiel plots are generally comic or romantic in nature, and frequently include elements of magic, fantastical creatures, and comically exaggerated characterizations of good and evil. In many of these operas he collaborated with the poet Christian Felix Weiße. Furthermore, Hiller was a teacher who encouraged musical education for women, his pupils including Elisabeth Mara and Corona Schröter. He was Kapellmeister of Abel Seyler's theatrical company, and became the first Kapellmeister of Leipzig Gewandhaus. To Hiller has been given the credit of being the originator of the Singspiel, the beginning of German comedy opera as distinct from the French and Italian developments. The most important of his operas were: Lottchen am Hofe (Lottie at court, 1760),Der Teufel ist los (The devil is loose, 1768), and Poltis, oder Das gerettete Troja (Poltis, or Troy rescued, 1782). The lyrics of all his Singspiele were of considerable musical value, and were long popular. Among his sacred compositions are: A Passion Cantata, Funeral Music in Honor of Hasse, a setting of the one hundredth Psalm; and a few symphonies. He died at the age of 76 in Leipzig.16 June 1858 – John Snow - https://en.wikipedia.org/wiki/John_SnowEnglish physician and a leader in the development of anaesthesia and medical hygiene. He is considered one of the founders of modern epidemiology, in part because of his work in tracing the source of a cholera outbreak in Soho, London, in 1854, which he curtailed by removing the handle of a water pump. Snow's findings inspired the adoption of anaesthesia as well as fundamental changes in the water and waste systems of London, which led to similar changes in other cities, and a significant improvement in general public health around the world. John Snow was one of the first physicians to study and calculate dosages for the use of ether and chloroform as surgical anaesthetics, allowing patients to undergo surgical and obstetric procedures without the distress and pain they would otherwise experience. He designed the apparatus to safely administer ether to the patients and also designed a mask to administer chloroform. He personally administered chloroform to Queen Victoria when she gave birth to the last two of her nine children, Leopold in 1853 and Beatrice in 1857 and was still not yet knighted, leading to wider public acceptance of obstetric anaesthesia. John Snow studied chloroform as much as he studied ether, which was introduced in 1847 by James Young Simpson, a Scottish obstetrician. He realised that chloroform was much more potent and required more attention and precision when administering it. Snow first realised this with Hannah Greener, a 15-year-old patient who died on 28 January 1848 after a surgical procedure that required the cutting of her toenail. She was administered chloroform by covering her face with a cloth dipped in the substance. However, she quickly lost pulse and died. After investigating her death and a couple of deaths that followed, he realized that chloroform had to be administered carefully and published his findings in a letter to The Lancet. Snow was a skeptic of the then-dominant miasma theory that stated that diseases such as cholera and bubonic plague were caused by pollution or a noxious form of "bad air". The germ theory of disease had not yet been developed, so Snow did not understand the mechanism by which the disease was transmitted. His observation of the evidence led him to discount the theory of foul air. He first published his theory in an 1849 essay, On the Mode of Communication of Cholera, followed by a more detailed treatise in 1855 incorporating the results of his investigation of the role of the water supply in the Soho epidemic of 1854. By talking to local residents (with the help of Reverend Henry Whitehead), he identified the source of the outbreak as the public water pump on Broad Street (now Broadwick Street). Although Snow's chemical and microscope examination of a water sample from the Broad Street pump did not conclusively prove its danger, his studies of the pattern of the disease were convincing enough to persuade the local council to disable the well pump by removing its handle (force rod). Snow later used a dot map to illustrate the cluster of cholera cases around the pump. He also used statistics to illustrate the connection between the quality of the water source and cholera cases. He showed that homes supplied by the Southwark and Vauxhall Waterworks Company, which was taking water from sewage-polluted sections of the Thames, had a cholera rate fourteen times that of those supplied by Lambeth Waterworks Company, which obtained water from the upriver, cleaner Seething Wells. Snow's study was a major event in the history of public health and geography. It is regarded as the founding event of the science of epidemiology. He died from stroke at the age of 45 in London.16 June 1869 – Charles Sturt - https://en.wikipedia.org/wiki/Charles_SturtCharles Napier Sturt, British officer and explorer of Australia, and part of the European exploration of Australia. He led several expeditions into the interior of the continent, starting from Sydney and later from Adelaide. His expeditions traced several of the westward-flowing rivers, establishing that they all merged into the Murray River, which flows into the Southern Ocean. He was searching to prove his own passionately held belief that an "inland sea" was located at the centre of the continent. Sturt found the conditions and climate in New South Wales much better than he expected, and he developed a great interest in the country. Sturt received approval from Governor Darling on 4 November 1828 to explore the area of the Macquarie River in western New South Wales. The party faced the ordeal of rowing back upriver on the Murray and Murrumbidgee, against the current, in the heat of an Australian summer. Their supplies ran out and, when they reached the site of Narrandera in April, they were unable to go any further. Sturt sent two men overland in search of supplies and they returned in time to save the party from starvation. But Sturt went blind for some months and never fully recovered his health. By the time they reached Sydney again, they had rowed and sailed nearly 2,900 kilometres of the river system. Sturt believed that it was his destiny to discover a great salt water lake, known as 'the inland sea', in the middle of Australia. At very least, he wanted to be the first explorer to plant his foot in 'the centre' of Australia. In August 1844, he set out with a party of 15 men, 200 sheep, six drays, and a boat to explore north-western New South Wales and to advance into central Australia. They travelled along the Murray and Darling rivers before passing the future site of Broken Hill. They were stranded for months by the extreme summer conditions near the present site of Milparinka. When the rains eventually came, Sturt moved north and established a depot at Fort Grey (today this site is within Sturt National Park). With a small group of men, including explorer John McDouall Stuart as his draughtsman, Sturt pressed on across what is now known as Sturt's Stony Desert and into the Simpson Desert. Unable to go further, he turned back to the depot. Sturt made a second attempt to reach the centre of Australia, but he developed scurvy in the extreme conditions. His health broke down and he was forced to abandon the attempt. John Harris Browne, surgeon on the expedition, assisted Sturt, took over leadership of the party and, after travelling a total of 3,000 miles (4,800 km), brought it back to safety. He died from heart failure at the age of 74 in Cheltenham, Gloucestershire.16 June 1977 – Wernher von Braun - https://en.wikipedia.org/wiki/Wernher_von_BraunGerman and later American aerospace engineer and space architect. He was the leading figure in the development of rocket technology in Nazi Germany and a pioneer of rocket and space technology in the United States. While in his twenties and early thirties, von Braun worked in Nazi Germany's rocket development program. He helped design and develop the V-2 rocket at Peenemünde during World War II. Though a member of the SS, following the war he was secretly moved to the United States, along with about 1,600 other German scientists, engineers, and technicians, as part of Operation Paperclip. He worked for the United States Army on an intermediate-range ballistic missile program, and he developed the rockets that launched the United States' first space satellite Explorer 1. In 1960, his group was assimilated into NASA, where he served as director of the newly formed Marshall Space Flight Center and as the chief architect of the Saturn V super heavy-lift launch vehicle that propelled the Apollo spacecraft to the Moon. In 1967, von Braun was inducted into the National Academy of Engineering, and in 1975, he received the National Medal of Science. He advocated a human mission to Mars. Von Braun also developed the idea of a Space Camp that would train children in fields of science and space technologies, as well as help their mental development much the same way sports camps aim at improving physical development. Von Braun took a very conservative approach to engineering, designing with ample safety factors and redundant structure. This became a point of contention with other engineers, who struggled to keep vehicle weight down so that payload could be maximized. As noted above, his excessive caution likely led to the U.S. losing the race to put a man into space with the Soviets. He died from pancreatic cancer at the age of 65 in Alexandria, Virginia.Famous Birthdays16 June 1801 – Julius Plücker - https://en.wikipedia.org/wiki/Julius_Pl%C3%BCckerGerman mathematician and physicist. He made fundamental contributions to the field of analytical geometry and was a pioneer in the investigations of cathode rays that led eventually to the discovery of the electron. He also vastly extended the study of Lamé curves. In 1836, Plücker was made professor of physics at University of Bonn. In 1858, after a year of working with vacuum tubes of his Bonn colleague Heinrich Geißler, he published his first classical researches on the action of the magnet on the electric discharge in rarefied gases. He found that the discharge caused a fluorescent glow to form on the glass walls of the vacuum tube, and that the glow could be made to shift by applying an electromagnet to the tube, thus creating a magnetic field. It was later shown that the glow was produced by cathode rays. Plücker, first by himself and afterwards in conjunction with Johann Hittorf, made many important discoveries in the spectroscopy of gases. He was the first to use the vacuum tube with the capillary part now called a Geissler tube, by means of which the luminous intensity of feeble electric discharges was raised sufficiently to allow of spectroscopic investigation. He anticipated Robert Wilhelm Bunsen and Gustav Kirchhoff in announcing that the lines of the spectrum were characteristic of the chemical substance which emitted them, and in indicating the value of this discovery in chemical analysis. According to Hittorf, he was the first who saw the three lines of the hydrogen spectrum, which a few months after his death, were recognized in the spectrum of the solar protuberances. In 1865, Plücker returned to the field of geometry and invented what was known as line geometry in the nineteenth century. In projective geometry, Plücker coordinates refer to a set of homogeneous co-ordinates introduced initially to embed the set of lines in three dimensions as a quadric in five dimensions. The construction uses 2×2 minor determinants, or equivalently the second exterior power of the underlying vector space of dimension 4. It is now part of the theory of Grassmannians, to which these co-ordinates apply in generality (k-dimensional subspaces of n-dimensional space). He was born in Elberfeld,Duchy of Berg,Holy Roman Empire.16 June 1915 – John Tukey - https://en.wikipedia.org/wiki/John_TukeyJohn Wilder Tukey, American mathematician best known for development of the Fast Fourier Transform (FFT) algorithm and box plot. The Tukey range test, the Tukey lambda distribution, the Tukey test of additivity, and the Teichmüller–Tukey lemma all bear his name. He is also credited with coining the term 'bit'. Early in his career Tukey worked on developing statistical methods for computers at Bell Labs where he invented the term "bit" in 1947. n 1970, he contributed significantly to what is today known as the jackknife estimation—also termed Quenouille–Tukey jackknife. He introduced the box plot in his 1977 book, "Exploratory Data Analysis". He is also the creator of several little-known methods such as the trimean and median-median line, an easier alternative to linear regression. He also contributed to statistical practice and articulated the important distinction between exploratory data analysis and confirmatory data analysis, believing that much statistical methodology placed too great an emphasis on the latter. Though he believed in the utility of separating the two types of analysis, he pointed out that sometimes, especially in natural science, this was problematic and termed such situations uncomfortable science. Tukey coined many statistical terms that have become part of common usage, but the two most famous coinages attributed to him were related to computer science. While working with John von Neumann on early computer designs, Tukey introduced the word "bit" as a contraction of "binary digit" The term "bit" was first used in an article by Claude Shannon in 1948. In 2000, Fred Shapiro, a librarian at the Yale Law School, published a letter revealing that Tukey's 1958 paper "The Teaching of Concrete Mathematics" contained the earliest known usage of the term "software" found in a search of JSTOR's electronic archives, predating the OED's citation by two years. This led many to credit Tukey with coining the term, particularly in obituaries published that same year, although Tukey never claimed credit for any such coinage. In 1995, Paul Niquette claimed he had originally coined the term in October 1953, although he could not find any documents supporting his claim.The earliest known publication of the term "software" in an engineering context was in August 1953 by Richard R. Carhart, in a RAND Corporation research memorandum. He was born in New Bedford, Massachusetts.16 June 1909 – Archie Carr - https://en.wikipedia.org/wiki/Archie_CarrArchie Fairly Carr, Jr., American herpetologist,ecologist and a pioneering conservationist. He was a Professor of Zoology at the University of Florida. In 1987 he was awarded the Eminent Ecologist Award by the Ecological Society of America. He made extraordinary contribution to sea turtle conservation by way of bringing attention to the world's declining turtle populations due to over-exploitation and loss of safe habitat. He started out as a high school science teacher before becoming a college professor. He published numerous books and articles, including Ulendo: Travels of a Naturalist in and out of Africa, High Jungles and Low, So Excellent a Fishe (about his green turtles), The Windward Road and several Time-Life books such as The Everglades and The Reptiles. He was also the author of the Handbook of Turtles, and with Coleman J. Goin, Guide to the Reptiles, Amphibians and Freshwater Fishes of Florida. While a serious scientific and nature writer, he also had a remarkable sense of humor, which led him to publish the parody of scientific taxonomic keys - his A Subjective Key to the Fishes of Alachua County, Florida, affectionately known as the "Carr Key". Carr was also known for his efforts in conservation, especially for sea turtles, helping convince Costa Rica to establish Tortuguero National Park in 1975. He was a co-founder of the Caribbean Conservation Corporation, which helps to save and monitor sea turtles in Tortuguero,Costa Rica. He was often joined in his conservation work by his wife Marjorie Carr, who was a major advocate for conservation in her own right. In 1952 Carr was awarded the Daniel Giraud Elliot Medal from the National Academy of Sciences. He was born in Mobile, Alabama.Events of Interest16 June 1884 – The first purpose-built roller coaster, LaMarcus Adna Thompson's "Switchback Railway", opens in New York's Coney Island amusement park. - https://www.history.com/this-day-in-history/first-roller-coaster-in-america-opensKnown as a switchback railway, it was the brainchild of LaMarcus Thompson, traveled approximately six miles per hour and cost a nickel to ride. The new entertainment was an instant success and by the turn of the century there were hundreds of roller coasters around the country. For five cents, riders would climb a tower to board the large bench-like car and were pushed off to coast 600 ft (183 m) down the track to another tower. The car went just over 6 mph (9.7 km/h). At the top of the other tower the vehicle was switched to a return track or "switched back" (hence the name). The new entertainment was an instant success and by the turn of the century there were hundreds of roller coasters around the country.16 June 1911 – IBM founded as the Computing-Tabulating-Recording Company in Endicott, New York. - http://www.techgetz.com/history-of-ibm/In 1911 the company that leased Unit record equipment, especially Hollerith punched cards and card readers to government bureaus and insurance agencies, became the Computing-Tabulating-Recording Company (CTR). Thomas J. Watson (1874-1956) took over in 1924, using the name “International Business Machines.” IBM expanded into electric typewriters and other office machines. Watson was a salesman and concentrated on building a highly motivated, very well paid sales force that could craft solutions for clients unfamiliar with the latest technology. His motto was “THINK”; customers were advised to not “fold, spindle or mutilate” the delicate cardboard cards.16 June 2012 – The United States Air Force's robotic Boeing X-37B spaceplane returns to Earth after a classified 469-day orbital mission. - https://www.space.com/16110-secret-x37b-space-plane-landing.htmlThe unmanned X-37B spacecraft, also known as Orbital Test Vehicle-2 (OTV-2), glided back to Earth on autopilot, touching down at California's Vandenberg Air Force Base at 5:48 a.m. PDT (8:48 a.m. EDT, 1248 GMT). The landing brought to an end the X-37B program's second-ever spaceflight, a mission that lasted more than 15 months with objectives that remain shrouded in secrecy. The X-37B stayed in orbit for 469 days this time, more than doubling the 225 days its sister ship, OTV-1, spent in space last year on the program's maiden flight. Officials at Vandenberg said the spacecraft conducted "on-orbit experiments" during its mission. Exactly what the spacecraft, which is built by Boeing, was doing up there for so long is a secret. The details of the X-37B's mission, which is overseen by the Air Force's Rapid Capabilities Office, are classified, as is its payload. This secrecy has led to some speculation, especially online and abroad, that the X-37B could be a space weapon of some sort — perhaps a sophisticated satellite-killer. Some experts also suspect that the vehicle may be an orbital spy platform. "This is a test vehicle to prove the materials and capabilities, to put experiments in space and bring them back and check out the technologies," Richard McKinney, the Air Force's deputy undersecretary for space programs.16 June 2016 – Shanghai Disneyland Park, the first Disney Park in Mainland China, opens to the public - https://www.dw.com/en/distinctly-chinese-disneyland-opens-in-shanghai/a-19332984Shanghai Disney Resort, the first Disney resort in Mainland China and the sixth worldwide, celebrated its historic Grand Opening today, culminating one of Disney's most ambitious projects ever. The wonder and imagination of Disney greeted the people of China in magical new ways as the gates opened to Shanghai Disneyland, a theme park like no other with the biggest, tallest castle in any Disney park, the first pirate-themed land and Disney's most technologically advanced park to date. Walt Disney Co. CEO Bob Iger and Chinese Vice Premier Wang Yang cut a red ribbon together, signaling the Communist Party's endorsement of the $5.5 billion (4.87 billion euro) resort - one of the largest foreign investments in China. The lavish ceremony featured a children's choir singing "When You Wish Upon a Star," as well as actors dressed as Sleeping Beauty, Donald Duck, and other Disney characters dancing on stage. The entrance of the park is called "Mickey Avenue" instead of "Main Street USA." Stores feature Minnie Mouse in traditional quipau dresses and the Wandering Moon Teahouse is modeled after a building in eastern China. Shanghai Disney Resort is filled with immersive Disney storytelling, thrilling attractions, spectacular live entertainment and memory-making experiences designed to inspire and delight Chinese guests. The world-class vacation destination includes a magical theme park with six themed lands, two imaginatively designed hotels, a Disneytown shopping and dining district, and Wishing Star Park recreational area.IntroArtist – Goblins from MarsSong Title – Super Mario - Overworld Theme (GFM Trap Remix)Song Link -https://www.youtube.com/watch?v=-GNMe6kF0j0&index=4&list=PLHmTsVREU3Ar1AJWkimkl6Pux3R5PB-QJFollow us onFacebook- Page - https://www.facebook.com/NerdsAmalgamated/- Group - https://www.facebook.com/groups/440485136816406/Twitter - https://twitter.com/NAmalgamatedSpotify - https://open.spotify.com/show/6Nux69rftdBeeEXwD8GXrSiTunes -https://itunes.apple.com/au/podcast/top-shelf-nerds/id1347661094RSS -http://www.thatsnotcanonproductions.com/topshelfnerdspodcast?format=rssInstagram - https://www.instagram.com/nerds_amalgamated/Email - Nerds.Amalgamated@gmail.comSupport via Podhero- https://podhero.com/podcast/449127/nerds-amalgamatedRate & Review us on Podchaser - https://www.podchaser.com/podcasts/nerds-amalgamated-623195

Programa “Mestizaje” Edición día 05-2020 Duración : 120 minutos (World music- folk-traditional-etc) Program “Mestizaje” Edition day 05-2020 Time : 120 minutes (World music- folk-traditional-etc MESTIZAJE 05-2020 DCV Revisión Lista World Music Chart Europe Mayo 2020 1-Sam Lee-Old Wow-The Garden Of England(Seeds of Love)-2020-UK - Cooking Vinyl Limited 2- Damir Imamovi? -Singer Of Tales-O basnlke gore snjezne-2020-Bosnia & Herzegovina- Wrasse Records 3-Tamikrest-Tamotait-Awnafin-2020-Mali- Glitterbeat Records 4-Santrofi-Alewa-Kokrokoo-2020-Ghana-Outhere Records 5-Santrofi-Alewa-Alewa-2020-Ghana-Outhere Records 6-Orkesta Mendoza-Curandero-Paleta-2020-USA/Mexico-Glitterbeat Records 7-Orkesta Mendoza-Curandero-Head Above Water-2020-USA/Mexico-Glitterbeat Records 8-Andrew Cronshaw-The Great Dark Water-The Voice of Silence-2020 England- Cloud Valley 9-Andrew Cronshaw-The Great Dark Water-The Wexford Carol-2020 England-Cloud Valley 10-Dzambo Agusevi Orchestra-Brasses For The Masses-Shukri Divosca-2020-Macedonia-Asphalt Tango Records 11-Aynur-Hedúr"Solace of Time"-Hedúr-Tukey-2020-Dreyer Gaido Revisión proyecto "Radio Tarifa"-Rumba Argelina(Remastered) 2019 12-Radio Tarifa-Rumba Argelina-2019 World Circuit 13-Radio Tarifa-Oye China-2019-World Circuit 14-Radio Tarifa-Nu Alrest-2019-World Circuit Novedad grupo Darash: Opera prima del mismo nombre-2020 Wild Punk 15-Darash--Darash-Skrothos-2020-Wild Punk 16-Darash--Darash-Irlandalus-2020-Wild Punk In Memoriam : Adiós a tres grandes músicos de la música africana que han fallecido en los últimos días. El nigeriano Tony Allen, el argelino-bereber Idir y el camerunés Manu Dibango. Tres músicos emblematicos que echaremos de menos y que nos quedaran sus conciertos en nuestros recuerdos. D.E.P Repaso de sus mejores proyectos: 17-Tony Allen-Film Of Life-Moving On-2014- Jazz Village 18-Tony Allen-Film Of Life-African Man-2014-Jazz Village 19-Tony Allen & Hugh Masekela-Rejoice-2020-World Circuit 20-Manu Dibango-African Voodoo-Ba-Kuba-1972- Soul Makossa 21-Manu Dibango-Wakafrika-Soul Makossa (feat Youssou N'Dour)-1994-World Circuit 22-Manu Dibango-Wakafrika-Biko(Peter Gabriel-Ladysmith Balck Mambazo-Geofrey Oryema)-1994- World Circuit 23-Manu Dibango-Anthology-Makosa Rock-World Circuit 24-Idir-Ici et ailleurs-La Boheme-2017-World Music Network 25-Idir-Idir-Said Ulamara (Said Oulamara)- World Music Network 26-Idir-Idir-Adrar Inu(Ma Montagne)- World Music Network EN IVOOX https://www.ivoox.com/s_p2_27864_1.html

Organic lawn care expert, Paul Tukey, joins me to talk about the basics on how you can take care of your lawn with an organic mindset. He's the author of The Organic Lawn Care Manual found here: https://amzn.to/3d6nazv, and an award-winning documentary producer, along with being a former host of People, Places, & Plants on HGTV, and is currently the Chief Sustainability Officer at glenstone.org.

Mann, Bobby, and Mike are joined by long-time listener and Grindbin Patreon member David from Australia! David brings Ozploitation back to the bin with the legendary Brian Trenchard-Smith flick, Turkey Shoot. We also make him explain himself for choosing Lunch Wagon... and the way back in the early days of the Grindbin.

In Episode 105 of Hidden Forces, Demetri Kofinas speaks with Jake Hanrahan about the crisis unfolding in the border region between Syria and Turkey following the US withdrawal of forces from northern Syria. This withdrawal precipitated the subsequent assault by Turkish Armed Forces on the Kurdish YPG-controlled region of Rojava. Jake Hanrahan is an independent journalist and documentary filmmaker based in the UK. He has reported from Syria, Iraq, southeast Turkey, and other conflict zones for HBO, Vice News, PBS Newshour, and BBC News, to name a few.  Turkish President Erdogan, after obtaining the consent of President Trump, began his invasion into the Kurdish YPG controlled region of Syria known as Rojava this past Wednesday. During Sunday’s “Face the Nation,” Secretary of Defense Mark Esper confirmed to Margaret Brennan that roughly 1,000 U.S. troops would be evacuated from northern Syria following Trump’s troop withdrawal announcement. There are also multiple reports of ISIS families and fighters previously captured and held by Kurdish forces starting to escape after Tukey’s bombardments. Also, Lebanese broadcaster al-Mayadeen reported Sunday that the Syrian army would enter Manbij and Kobani in the next 48 hours, based on an agreement with the Syrian Democratic Forces (the latter, according to Mohammed Shaheen, the deputy chairman of Euphrates region told North-Press).  It seems that what we are seeing transpire in the Middle East is the disintegration of artificially constructed national borders around sectarian lines. The forces being unleashed have thus far remain contained within the Greater Middle East, but Turkey’s involvement creates the further potential for spillover into the Balkans and southern Europe at some indeterminate future date. Additionally, Turkey has been flexing its geopolitical muscles where Greece is concerned in recent years, and it is no longer inconceivable to imagine that its troubled relationship to the EU and its membership in NATO will prove insufficient as deterrents for curbing Turkish military aggression or the expansionary ideas of Erdoğan in the Aegean.  This conversation is meant to help Hidden Forces listeners develop some context for what has transpired over the past week, the significance of Trump’s decision, and the implications moving forward.  Hidden Forces is listener funded. We rely on you to help us keep the program free of corporate advertising. You can help us do that by subscribing to one of our three content tiers through the Hidden Forces Patreon Page. All subscribers also gain access to our overtime feed, which can be easily be added to your favorite podcast application. Your support is deeply appreciated. Producer & Host: Demetri Kofinas Editor & Engineer: Stylianos Nicolaou Subscribe & Support the Podcast at http://patreon.com/hiddenforces Join the conversation on Facebook, Instagram, and Twitter at @hiddenforcespod

Today on the show I talk about Fitbit lost my account. As in a decade of information went up in smoke (thankfully most of the weight tracking is in my fitness pal. Tomorrow will be one week without so I ended up going and getting an Apple Watch Series 4 after hearing some friends say how cool they are. Apple Watch Features Really customizable screen Apple health seems to integrate with everything It does NOT grade how you sleep but there are apps that integrate with Apple health that do. I can't really tell as I can't login into my Fitbit account, but my Apple Watch shows that my resting energy was 2157 after one day. This would explain why if I eat 1900 calories or less I would lose weight. While Fitbit's are geared toward measuring calories in, activity and showing you the deficit, Apple Health is more overall health. My Withings scale integrates with myfitness pal and you can use my fitness pal to integrate with Apple health. Nonhealth things I love. I love that I can listen to my podcasts and have my phone in my pocket and skip and fast forward etc on my watch. I love that I don't have to sync with my phone. It operates on its own. I realize the Fitbit Charge is $150 and the Apple Watch is close to $500 so its not a fair comparison. It would be better to compare it to the Fitbit Ionic which is $250. In the end, I'm happy with my Apple watch. My wallet is lighter which makes it easy to walk. Built-in Accountability Partner In the Apple Activity App where you can set goals for calories burned, exercise minutes, and how many times you stand a day, you can share that with contacts on your phone. What About Fitbit Challenges? - Enter Stridekick I found a great app that is free (as long as your group is under 10 people) called Stridekick  that allows you to make challenges where the person with the most steps wins after a certain number of days. Here are the types of challenges: Streak: Track the number of consecutive days you've successfully hit your step goals, and motivate your fellow steppers in streak mode. Target: Aim for a total step goal for the challenge and track your pace and make sure you will your target before the end. Journey: Challenge yourself in a virtual long-distance race. Participants can track in real-time where they are along the journey's path. Leaderboard: Leaderboard allows competitive steps to achieve the ultimate glory by making it to the top of the leaderboard for best steps Stridekick Let's Everyone Participate No Matter the Platform According to their website: Stridekick offers cross-device compatibility making it the perfect place for everyone to play. We support most major fitness trackers, including: Android Phones - Android 4.2 or above through the Google Fit app. Apple Watch Fitbit - Zip, One, Flex, Charge, Charge HR, Surge, Alta, Blaze, MobileTracker app Garmin - vívofit, vívofit 2, vívosmart, vivosmart HR, vívoactive, vivokí, ** Google Fit (Android, Pebble, Xiaomi) IPhone 5s and above - Apple Health App (Polar, Pebble, Xiaomi, and more) Misfit - Flash Cyclist, Flash, Link, Ray, Shine, Shine2, Speedo Shine, Swarovski Activity Crystal Withings - Pulse, Pulse O2, Activité Pop, Activité, Activité Steel Note: We are always looking to expand our list of supported devices. If you don't see your device in the list above, let us hear about it! **Stridekick can usually connect with the Garmin Forerunner and Fenix devices, however, we can only pull from devices that report steps. If your device doesn't report steps, it will not sync with Stridekick. Freshly Food - Good, Quick Food There are so many food delivery services, and I've tried some but being a finicky eater (no mushrooms, no peppers, nothing too spicy) it's hard to find one that works for me.  I was very impressed with the food from Freshly. I loved the Tukey meatballs with Zoodles, and other dishes. The peppercorn steak was really good for coming out of a microwave.  Unlike other delivery services where there is some food prep, this is like someone delivering gourmet TV dinners. You pop 'em in the microwave and three minutes later you're eating good food.  I will say there were some inconsistencies. The first time I ordered the Turkey meatballs they were amazing. The second time, they were great. This week I felt like the chef drop some pepper in the mix as it made my eyes water it was so spicey. I even checked on the website and this dish is not supposed to be spicy so I don't know what happened.  Time or Money I mentioned in a previous episode I threw together some things into a bowl with a nod towards chipotle. It was  one cup of brown rice 3-5 oz of cubed chicken Grape tomatoes a sprinkling of mozzarella cheese. Shredded iceberg lettuces A dash of salad dressing.  When I did the math it costs me $4.72 per serving and takes me three minutes to make (and that includes cubing the chicken and slicing the tomatoes in half).  The price of a freshly meal is $12.50 a meal. The time you are saving is shopping and putting away the groceries.  They make it really easy to start and cancel (although they really try to get you to stay). They have gluten-free, and vegetarian meals as well. Most of their meals are between 450-700 calories. The meals I purchased were pretty heavy with salt. They were shipped well, and nothing was ever in danger. They pack them well to stay cold.  Check them out at www.logicallos.com/freshly Join the Logical Losers and Support the Show Through Patreon See www.logicallosers.com

Garfield has a dumb interaction with a tetrapod of bilateral symmetry, and I embarassingly mix-up Tukey and Saudi Arabia. So pretty much a standard episode. Hosts: Jon Gibson, Danny Gibson (https://twitter.com/fasterduckworth) Today's strip Become a Patron! Or visit these other fine internet URLs: BJD Homepage | BJD Twitter | BJD Facebook Page | Pitchdrop Network Homepage

Background: Metabolic syndrome (MetS) is associated with increased risk of cardiovascular disease (CVD). One important feature underlying the pathophysiology of many types of CVD is microvascular dysfunction. Although components of MetS are themselves CVD risk factors, the risk is increased when the syndrome is considered as one entity. We aimed to characterize microvascular function and some of its influencing factors in the course of MetS development. Methods: Development of MetS in C57BL/6 mice on a high-fat diet (HFD, 51% of energy from fat) was studied. The initial phase of MetS (I-MetS) was defined as the first 2 weeks of HFD feeding, with the fully developed phase occurring after 8 weeks of HFD. We characterized these phases by assessing changes in adiposity, blood pressure, and microvascular function. All data are presented as mean +/- standard error (SEM). Differences between cumulative dose-response curves of myograph experiments were calculated using non-linear regression analysis. In other experiments, comparisons between two groups were made with Student's t-test. Comparisons between more than two groups were made using one-way ANOVA with Tukey post-hoc test. A probability value

Guest Paul Tukey, Filmmaker, author and Founder of the Safe Lawns Foundation, talks about his documentary film, Chemical Reaction, which charts the medical, legal and political fight to ban lawn pesticides in Hudson, QuebecSafe Lawns Foundation

Interview with Erik from Boulder-Hill.Net

[audio:http://traffic.libsyn.com/joelampl/GGW026.mp3] Click the Arrow to Listen Now This show is an interview with Paul Tukey. You might know Paul as the founder of SafeLawns.org or as host of People, Places and Plants on HGTV, or perhaps, author of The Organic Lawncare manual. Today he's back to fill us in on his biggest and most exciting project yet. It's a documentary movie, called A Chemical Reaction and Paul's the Executive Producer. It's an amazing, true story of how one woman's persistence, finally set the wheels in motion sweeping Canada for a chemical free ban on ornamental pesticides. Will it have an affect in the U.S? Well stay tuned to find out. The post 026 GGW – A Chemical Reaction; An Interview with Exective Producer, Paul Tukey appeared first on Growing A Greener World®.

[audio:http://traffic.libsyn.com/joelampl/GGW026.mp3] Click the Arrow to Listen Now This show is an interview with Paul Tukey. You might know Paul as the founder of SafeLawns.org or as host of People, Places and Plants on HGTV, or perhaps, author of The Organic Lawncare manual. Today he’s back to fill us in on his biggest and most exciting project yet. It’s a documentary movie, called A Chemical Reaction and Paul’s the Executive Producer. It’s an amazing, true story of how one woman’s persistence, finally set the wheels in motion sweeping Canada for a chemical free ban on ornamental pesticides. Will it have an affect in the U.S? Well stay tuned to find out. The post 026 GGW – A Chemical Reaction; An Interview with Exective Producer, Paul Tukey appeared first on Growing A Greener World®.

[audio:http://media.libsyn.com/media/joelampl/GGW016.mp3] Click the Arrow to Listen Now This week Joe Lamp'l interviews Paul Tukey, author of The Organic Lawn Care Manual, Founder of Safelawns.org and the American Horticulture Society's Communicator of the year in 2006. He's also host of HGTV's People, Places & Plants. Paul shares some very interesting news and fills us in on his busy life campaigning for safer, more eco-friendly lawns, gardens and landscapes. All that and more… Click to View Show Notes The post 016 GGW – Safelawns Founder, Paul Tukey appeared first on Growing A Greener World®.

[audio:http://media.libsyn.com/media/joelampl/GGW016.mp3] Click the Arrow to Listen Now This week Joe Lamp’l interviews Paul Tukey, author of The Organic Lawn Care Manual, Founder of Safelawns.org and the American Horticulture Society’s Communicator of the year in 2006. He’s also host of HGTV’s People, Places & Plants. Paul shares some very interesting news and fills us in on his busy life campaigning for safer, more eco-friendly lawns, gardens and landscapes. All that and more… Click to View Show Notes The post 016 GGW – Safelawns Founder, Paul Tukey appeared first on Growing A Greener World®.

Background: Previous studies reported an increase of upper body mass index (BMI) quantiles for formula fed infants compared to breastfed infants, while corresponding mean differences were low. The aim of this study was to assess the impact of known risk factors for childhood obesity on the BMI distribution. Methods: Data on 4,884 children were obtained at obligatory school entry health examinations in Bavaria (Germany). Exposure variables were formula feeding, maternal smoking in pregnancy, excessive TV-watching, low meal frequency, poor parental education, maternal overweight and high infant weight gain. Cumulative BMI distributions and Tukey mean-difference plots were used to assess possible shifts of BMI distributions by exposure. Results: Maternal overweight and high infant weight gain shifted the entire BMI-distribution with an accentuation on upper quantiles to higher BMI values. In contrast, parental education, formula feeding, high TV consumption, low meal frequency and maternal smoking in pregnancy resulted in a shift of upper quantiles only. Conclusion: The single shifts among upper parts of the BMI distribution might be due to effect modification of the corresponding exposures by another environmental exposure or genetic predisposition. Affected individuals might represent a susceptible subpopulation of the exposed.