Podcasts about chrysalis

Life stage of some insects undergoing transformation

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Oncology Brothers
Lung Cancer ASCO 2026 Highlights: LIBRETTO-432, CROWN Update, CHRYSALIS-2, HARMONi-6

Oncology Brothers

Play Episode Listen Later Jun 5, 2026 22:00


Welcome back to the Oncology Brothers podcast! In this episode, we were joined by Dr. Isabel Preeshagul from Memorial Sloan-Kettering to discuss the latest advancements in lung cancer presented at ASCO 2026. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Apple Podcast: https://podcasts.apple.com/us/podcast/oncology-brothers-practice-changing-cancer-discussions/id1653340966 Follow us on social media: X/Twitter: https://twitter.com/oncbrothers ⁠Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/ We dived into four key studies that could change clinical practice: LIBRETTO-432: exploring the promising event-free survival data with selpercatinib in RET-positive disease and its implications for adjuvant therapy. CROWN 7yr Update: seven-year progression-free survival results with lorlatinib in ALK-positive non-small cell lung cancer and the associated side effects. CHRYSALIS-2: exciting findings regarding amivantamab for atypical EGFR mutations and its potential to become the new standard of care. HARMONi-6: dual-headed drug ivonescimab combined with chemotherapy in metastatic squamous cell lung cancer and its intriguing results. We also touched on the importance of molecular testing for all patients, regardless of stage or histology, and highlighted the latest updates on tarlatamab in small cell lung cancer. Tune in for an insightful discussion that aims to keep our oncology community informed and engaged with the latest research and treatment options! Don't forget to like, subscribe, and check out our other episodes for more insights on oncology treatments, conference highlights, and FDA approvals. #ASCO2026, #LungCancer, #ALKPositive, #RETPositive, #OncologyBrothers

ScienceLink
Recap día 1 y 2

ScienceLink

Play Episode Listen Later May 31, 2026 38:19


En este primer RECAP de la Reunión Anual de la Sociedad Americana de Oncología Clínica, el Dr. Fabián Martínez, oncólogo médico adscrito al Centro Médico ABC, y el Dr. Raúl Mellado Orellana, oncólogo médico adscrito al Instituto Nacional de Neurología y Neurocirugía, analizan de manera crítica los hallazgos más relevantes presentados durante los primero dos días en Chicago, IL. La discusión abre con el análisis del estudio fase III lidERA, el cual evalúa el uso de giredestrant —un degradador selectivo del receptor de estrógenos por vía oral— en comparación con la terapia endocrina estándar como adyuvancia durante 5 años en pacientes con cáncer de mama RE+/HER2- temprano.En el ámbito del CPCNP, se revisan múltiples investigaciones de alto impacto clínico. En primer lugar, se evalúa el estudio fase III WU-KONG28, que demuestra la eficacia de sunvozertinib frente a la quimioterapia convencional en la primera línea de tratamiento para pacientes con inserción del exón 20 de EGFR. Posteriormente, se examina el estudio fase III OptiTROP-Lung05, que demuestra la superioridad de la combinación sacituzumab tirumotecan más pembrolizumab frente a la monoterapia con pembrolizumab en pacientes con CPCNP PD-L1. Finalmente, se analizan los datos actualizados de supervivencia global del estudio CHRYSALIS-2 (cohorte C, amivantamab con o sin lazertinib), así como el seguimiento a 7 años del estudio CROWN (lorlatinib frente a crizotinib en primera línea CPCNP ALK+).Por último, los ponentes discuten los avances en tumores genitourinarios. Se profundiza en el estudio EV-302/KEYNOTE-A39, que evalúa la combinación de enfortumab vedotin junto a pembrolizumab en carcinoma urotelial metastásico no tratado previamente y cómo continúa obteniendo respuestas completas con la continuidad del tratamiento. En el escenario del cáncer renal de células claras, se revisa el análisis del ensayo fase III KEYNOTE-564 enfocado en el valor del ctDNA como biomarcador posterior a la nefrectomía. Referencia:Este contenido se basa en la interpretación crítica de la evidencia científica disponible, así como en la experiencia clínica del o los ponentes como profesionales de la salud en instituciones de referencia.Para profundizar en los conceptos discutidos, se recomienda al profesional de la salud consultar literatura científica vigente, guías clínicas internacionales y la normatividad aplicable en su país.

ASCO Guidelines Podcast Series
Therapy for Stage IV NSCLC With Driver Alterations: ASCO Living Guideline Update 2026.3.1 Part 2

ASCO Guidelines Podcast Series

Play Episode Listen Later May 26, 2026 19:00


Dr. Joshua Reuss returns to the podcast to discuss the update to the living guideline on stage IV NSCLC with driver alterations. The conversation focuses on new cancer treatment strategies for patients with advanced NSCLC and EGFR mutations, including classical EGFR alterations (exon 19 deletions, exon 21 L858R substitution) and rarer alterations (exon 20 insertion mutations). Dr. Reuss discusses results from clinical trials, including MARIPOSA and CHRYSALIS-2 and how these impacted first-line and subsequent line treatment recommendations. He looks to the future on what new evidence and potential updates are in the pipeline for this living guideline. Read the full living guideline "Therapy for Stage IV Non-Small Cell Lung Cancer with Driver Alterations, ASCO Living Guideline Version 2026.3.1"  LINK TO FULL TRANSCRIPT

Being an Engineer
S7E22 Amelia Howe | Developing Medical Device Injectrodes for Pain Reduction, & Project Management Best Practices

Being an Engineer

Play Episode Listen Later May 22, 2026 52:48 Transcription Available


Send us Fan MailAmelia Howe is a biomedical engineer and R&D project manager whose career spans startups, research labs, and established medical device companies. She currently leads cross-functional development programs at COLTENE, where she coordinates teams across engineering, quality, regulatory, and manufacturing to bring new medical devices from concept to international launch.Amelia's journey into engineering began with a pivotal shift early in her academic career. While studying at The University of Akron, she transitioned from nursing to biomedical engineering after discovering the field through biomechanics research. Working in Dr. Brian Davis's lab, she contributed to innovative research on shear forces and biomechanics, helping analyze how human movement affects pressure and stress on the body.After graduating summa cum laude, Amelia joined Neuronoff, Inc. as its first employee. In the fast-moving startup environment, she wore nearly every hat imaginable—conducting research, developing prototypes, establishing quality systems, and contributing to core patents. She played a key role in the early development of the Injectrode neuromodulation technology while helping build the company's quality management system toward ISO 13485 compliance.Over time, Amelia gravitated toward project leadership, recognizing that even highly talented engineers need structured coordination to ensure complex products make it through development. She moved into project management roles, overseeing multiple technical programs simultaneously and aligning engineering, regulatory, and business teams around clear timelines and milestones.Today, in addition to her role at COLTENE, Amelia is launching Chrysalis Business Consulting, where she provides project management and business development support to medical device startups. With both an engineering background and an MBA from Quantic School of Business and Technology, she brings a rare perspective that blends technical depth with strategic business insight. LINKS:Amelia Howe LinkedIn: https://www.linkedin.com/in/ameliaehowe/Company website: https://www.linkedin.com/company/chrysalis-business-consulting-llc/Aaron Moncur, host Subscribe to the show to get notified so you don't miss new episodes every Friday.The Being An Engineer podcast is brought to you by Pipeline Design & Engineering. Pipeline partners with medical & other device engineering teams who need turnkey equipment like cycle test machines, custom test fixtures, automation equipment, assembly jigs, inspection stations and more. You can find us at www.teampipeline.usWatch the show on YouTube: www.youtube.com/@TeamPipelineus 

Bill Bennet Fit Over 50
Chrysalis ( Tour Rehearsals )

Bill Bennet Fit Over 50

Play Episode Listen Later May 21, 2026 3:51


Chrysalis ( Tour Rehearsals ) by Bill Bennett

Recording & Mixing
Advanced EQ Tips

Recording & Mixing

Play Episode Listen Later May 19, 2026 26:12


In this episode, Eddie Bazil breaks down the different types of EQ, explains their most common uses in mixing and production, and demonstrates how they shape and enhance sound with practical audio examples.Chapters00:00 - Introduction00:48 - What EQ Is And Different Types01:33 - Active And Passive02:45 - Linear Phase And Minimum Phase03:46 - High-Pass and Low-Pass Filters04:36 - Example 1: Using Synth Filters06:47 - Common Functions Of EQ07:27 - Example 2: Shaping A Kick Drum10:31 - Example 3: Rebalancing An Acoustic Guitar13:48 - Selecting The Right EQ Shape15:55 - Managing Redundant Frequencies18:15 - Example 4: Rebalancing A Mix#PultecEQP-1 #XferSerum #BozDigitalTransgressor2 #EventideSplitEQ #SonibleEntropyEQ+ #SSLNativeXSaturator #SSLValveComp #TokyoDawnTDRArbiterTrack CreditsExample 2: from 'Puppet' by John Walden.Example 3: from James Perret.Example 4: from 'Another Way' by forester. Written, performed and produced by René Schneeberger.https://foresterdnb.bandcamp.com/musichttps://open.spotify.com/intl-de/artist/2BtzZiEDaReXLveskYtYkmhttps://soundcloud.com/foresterdnbhttps://cambridge-mt.com/Eddie Bazil BiogEddie Bazil launched his music industry career at the age of 17 as a synth programmer for a range of Electro / New Wave bands, including Art Of Noise, Spandau Ballet, Pet Shop Boys, Bobin, Paul Dee, DJ Krush, DJ Shadow, Jets Orchestra, and many more. By his 20s, he was working as a sound designer for Akai, Roland, Emu/Ensoniq, eventually signing on exclusively with the latter. Later, due to a growing demand for software instruments and libraries, Eddie began developing libraries for various software manufacturers, including Native Instruments, Kiesel, Sound Effects Library, Rob Papen, Arturia, and Propellerheads.During this time, he trained in music production. He soon gained several prominent contracts working with some notable artistes such as Busta Rhymes, Greensleeves, 9 Bar, SFP, Sleeveless, Chris Campbell and Gam Productions. He contracted to Island Records and Chrysalis as a producer and remixer, and was commissioned to write the score for Macbeth that ran at 2 Way Mirror at Alexander Palace for the Cambridge Shakespeare Company. This led to him offering educational workshops and classes, and becoming a contributing creator and Forum moderator for Sound On Sound.Recently, he was invited by the Recording Academy to become a professional member, approved educator, and mentor for their member base. Eddie now concentrates on providing private sound design and mixing/production tuition, and creating content for Sound On Sound magazine.https://eddiebazil.co.uk/Catch more shows on our other podcast channels: https://www.soundonsound.com/sos-podcasts

KANNMIX Podcast
KANNMIX 67 | DJ Chrysalis & mp rotator

KANNMIX Podcast

Play Episode Listen Later May 19, 2026 127:41


Have you had a chance to meet Rupert and Noodles yet? It's mp rotator's (@spicyboy420420) cat and @djchrisellis beloved dog. Silly intro for a two hours cut out of five from a recent b2b — a little rough and ready at times, but I think it carries a very good energy throughout.

Chapel of Light podcast
The Chrysalis of Glory - Pst Tochukwu Okpara

Chapel of Light podcast

Play Episode Listen Later May 17, 2026 40:44


StarDate Podcast
Moon and Saturn

StarDate Podcast

Play Episode Listen Later May 12, 2026 2:20


Today, Saturn and its system of moons and rings look calm and peaceful. But things might have been much more chaotic in the fairly recent past. A collision between two moons might have destroyed one of them, changed the orbit of the other, and led to the birth of yet another moon and the planet’s rings. Researchers have been trying to explain some oddities in the Saturn system. The planet itself is tilted far more than it should be, for example. The biggest moon, Titan, follows a more lopsided orbit than expected. And the moon is moving away from Saturn by about four inches per year. A few years ago, a team proposed that Saturn once had another big moon, which the team called Chrysalis. Interactions between the moons might have kicked Chrysalis so close to Saturn that it was ripped apart, forming the rings. But this year, another team came up with a slightly different scenario. It, too, involves a second moon. It collided with Titan a few hundred million years ago, changing Titan’s orbit. Debris from the impact formed the present-day moon Hyperion. The activity caused two other moons to ram together as well. Both moons quickly re-formed, with the leftovers spreading out to form the rings as recently as 50 million years ago. This model explains many of the system’s oddities – bringing order to a chaotic arrangement. Look for Saturn near our moon at dawn tomorrow. The planet looks like a bright star, low above the horizon. Script by Damond Benningfield

The Manspace
The Beginning of the End of The ManSpace

The Manspace

Play Episode Listen Later May 6, 2026 33:32


Send us Fan MailWell spacemen, we've almost reached the end of this iteration of The ManSpace. So, today, we ask for your input--what do you want us to cover in the last 10 episodes? Text us and tell us 512-766-5154. Keywordsmasculinity, men's mental health, male friendships, relationships, personal growth, podcast finale, men's issues, emotional maturity Key TopicsThe evolution of the Man Space podcast over 5 yearsThe importance of male friendships and emotional connectionTopics of masculinity, mental health, and personal growthListener engagement and future content ideasSound Bites"The man space is dying.""This will call this the Chrysalis episode."Chapters00:00 Introduction and Context01:33 The Announcement of Change04:36 Exploring the Landscape of Masculinity07:29 Top Topics in Men's Mental Health10:42 Reflections on Male Relationships13:03 The Interplay of Relationships and Mental Health16:58 The Importance of Male Friendships19:29 Analyzing Male Friendships vs. Romantic Relationships24:33 The Value of Emotional Expression Among MenSpread the word! The Manspace is Rad!!

Zo Williams: Voice of Reason
Friendfluence as the modern social chrysalis — a bounded communal container of repeated relational pressure that forces the liquefaction of hyper-individualistic dating patterns, allowing new forms of intercepted, wakeful, and wake-worked relating to em

Zo Williams: Voice of Reason

Play Episode Listen Later May 5, 2026 78:46


You thought you were dating. You were actually performing — alone, in the dark, with no witnesses. The modern dating machine sold you a lie so seductive it felt like freedom: that real love happens in private, that self-sabotage is just “my process,” and that needing people to see you makes you weak. That lie is older than the apps. It is colonial. It is the same psychological split that taught generations to distrust communal eyes and call isolation strength. Friendfluence is the antidote that refuses to stay quiet. It is not cute group dates or asking your friends for advice. It is the deliberate return of the container — the group as centerline, as living mirror, as live audit that will not let your old pattern complete itself in silence. When your people are allowed to witness the actual version of how you love, the inherited fracture starts to crack. The nervous system that learned to perform safety while hiding its damage finally gets data it cannot ignore. This is not about giving up power. It is about exposing the version of you that misuses power in private. By the end of this conversation, some part of you will feel it: you have been catching your own patterns late. The question is no longer whether you need witnesses. The question is whether you're finally ready to stop protecting the version of you that needed to stay unseen.

Zo Williams: Voice of Reason
Friendfluence as the modern social chrysalis — a bounded communal container of repeated relational pressure that forces the liquefaction of

Zo Williams: Voice of Reason

Play Episode Listen Later May 5, 2026 74:46 Transcription Available


You thought you were dating. You were actually performing — alone, in the dark, with no witnesses. The modern dating machine sold you a lie so seductive it felt like freedom: that real love happens in private, that self-sabotage is just “my process,” and that needing people to see you makes you weak. That lie is older than the apps. It is colonial. It is the same psychological split that taught generations to distrust communal eyes and call isolation strength. Friendfluence is the antidote that refuses to stay quiet. It is not cute group dates or asking your friends for advice. It is the deliberate return of the container — the group as centerline, as living mirror, as live audit that will not let your old pattern complete itself in silence. When your people are allowed to witness the actual version of how you love, the inherited fracture starts to crack. The nervous system that learned to perform safety while hiding its damage finally gets data it cannot ignore. This is not about giving up power. It is about exposing the version of you that misuses power in private. By the end of this conversation, some part of you will feel it: you have been catching your own patterns late. The question is no longer whether you need witnesses. The question is whether you're finally ready to stop protecting the version of you that needed to stay unseen. 

Episode One – 9.2.16
Post Punk Plus Podcast Playlist 151 – Original upload 3.5.26

Episode One – 9.2.16

Play Episode Listen Later May 3, 2026 120:05


This playlist is 73% vinyl friendly. Not bad. From 2016, the TechDas Air Force One Premium turntable might well have been aimed initially at the present user of said plane, if features like vacuum clamping, pneumatic bearings, the Disc suction system and an impressive Wow & Flutter ratio of 0.03% (WRMS) were his or her thing and depending on the spec required it retailed at between $140,000 and $152,000. You read that right. Any track marked * has been given either a tiny or a slightly larger 41 Rooms tweak/edit/chop and the occasional tune might sound a bit dodgy, quality-wise. On top of that, the switch between different decades and production values never helps in the mix here. Lyric of Playlist 151 Nearly as good as captured cinematically. A busy day in the life of Joni. 00.00 (Intro) THE FLAMINGOS – Stars (Edit) – Unreleased demo – 1983. Episode #1 for info. 00.41 NEW ORDER – Sunrise (Writing Session Recording) – Low-Life, Definitive Edition box set – Warner Music – 2023 Yep, slower than the version most will know – either from the album or when played live, or indeed the equally vocal-less ‘Rough Mix’ take the band generously gave me for the Discreet Campaigns v/artist cassette that kickstarted the short-lived Rorschach Testing label – but it’s another where you’re practically hearing the band getting to grips with a rhythm and/or the shell of a song. My money’s on Hooky being the one who suggested the tempo should be taken up a notch or two. 04.48 THE WAKE – The Calendar (demo) – Unreleased – 1983 Onwards to become The Torn Calendar but here it was one of three tracks demo’d (along with ‘Places’ {pre Send Them Away} and Rise and Shine) on a TEAC 4-track reel to reel the band borrowed from me. They certainly made far better use of it than I ever did. The written lyrics given to Bedford’s Katie Possum at some point, along with her review in the local paper of the band’s second gig at Winkles… and that’s Stephen, my dog, Flanagan and Mac at my house the day before said gig. 08.10 A CERTAIN RATIO – And Then She Smiles – Force, LP – Factory – 1986 It’ll be no surprise to those that know me that I’m a bigger fan of the ‘tougher’ earlier ACR but here Jez Kerr’s voice is so sublime over a more ‘reflective’ sound. 11.59 THE OUBLIETTE – That’s Enough – Stream only – 2026 This is a complete first! Here – by complete accident – sits the first ever AI generated track to feature on 41 Rooms! And who knows re the video? It’s not an area I intend actively searching out, so expect them very infrequently but The Oubliette’s Youtube channel has a bucket load of tracks if you fancy your ’80s indie and darkwave-sounding tunes on the ‘artificial’ side. 15.18 LOVELAND (feat RACHEL McFARLANE) – Let the Music (Lift You Up) (Full On Vocal Radio Edit) – 12″ – Big Beat – 1994 ‘The Full On Vocal Mix, with its pounding piano and hackneyed lyrics, is undeniably old-fashioned and is about as cheesy as a lorry-load of Wotsits. But it comes with a guarantee to create absolute mayhem on all but the most elite of dancefloors. For those DJs who are more concerned about their own credibility than their audience’s enjoyment levels, there is also a much cooler garage-style remix from Olympic’s Bottom Dollar crew plus some deep and funky dubs‘. – Andy Beevers, Record Mirror (Music Week), 5.3.94 There are times when storming vocals, ‘less than critical’ lyrics and hands in the air are all you need… and this Big Beat belter had me smiling back then. 18.30 MARCO BENEVENTO – Houdini – Glera, LP – Big Crown Records – 2026 A bit of a broken beat and summery, Latin thing going on here, like someone taking a late ’60s Sergio Mendes vocal snippet on a wild ride. 20.59 MIDNIGHTROBA – Day’s Gon’ Come – Raise A Symphony, 2LP – Sonder – 2026 Roba El-Assawy has been heard far too infrequently since her days fronting Attica Blues. 22.42 THE ISLEY BROTHERS (feat RONALD ISLEY and ANGELA WINBUSH) – Float On (Bad Boy Remix) (Instrumental edit) * – Floatin’ On Your Love, 12″ – 4th & Broadway – 1996 I cut out all the ‘bump and grind’ lurrrv thang lyrics, as it was the beats, bv’s and ad libs stuff on this mix that made me buy the 12″ in the first place. Oh, and Ronald Isley could always sound like he was just itching to break into Summer Breeze any second. No bad thing. 24.31 HONEY DIJON (feat. JACOB LUSK) – Satisfied – The Nightlife, download only – Someothershit -2026 On first listen I briefly thought that Anohni (previously of Antony and the Johnsons) was on board here sounding soul sexy but it’s ‘competitor in American Idol’ (Season 10, apparently), Jacob Lusk quivering and sailing high on Ms Dijon’s production. African beat vibes sparkling all the way. 28.32 THE YOUNG DISCIPLES – Apparently Nothin’ – 12″ – Talkin’ Loud – 1991 Early in the Gilles Peterson and Norman Jay’ label catalogue and one hell of a funky strut. The wonderful Straight No Chaser mag was always a must read, even if a lot of the sounds and artists passed me by. I could still find tunes I’d never happen on anywhere else, unless I’d stood all day in London Soho’s Mr Bongo’s shop (or the likes) back in the day. 32.55 RÓISÍN MURPHY – If We’re In Love – 12″ – Echo – 2005 Strut Part 2! Between her Moloko days and solo career the Arklow, Ireland girl is a regular of sorts at 41 Rooms. Not sure about that sleeve cover, though. 37.20 CAN – I Want More – 7″ – Virgin – 1976 ‘German experimental electronic artist makes the UK’s Top 30 singles chart’ shock, horror probe. 40.34 FINITRIBE – Catch The Whistle – Promo 12″ only – Finiflex – 1993 First heard by me as a Tommy Vance-spoken ‘One FM exclusive’ on the Beeb’s lead radio station, though my mixtape forever played it slower than intended. Still rather it a tad pitched down. Squelchy sounding snares were often the order of them days. 46.14 ZIN MIYAKEZAWA – A Sanctuary Of Twilight Filled With Tranquility * – Classical Music, Vol. 108- Instrumental BGM – Download only – Audiostock – 2025 BGM = Background music, but ‘Incidental’ sounds so much classier, don’t you think? I’m slightly doubting whether Zin Miyakezawa is a real human but either way A Sanctuary… brings to mind Richard Harvey’s Elegy (the theme from TV’s 1983 Shroud For A Nightingale) and to a certain degree, parts of Harry’s Theme – Terminus (Silent Witness, S10, E10), and as all three have now made it to 41 Rooms you’ll instantly remember them all, I’m sure. You’re welcome, though a proper musician would tell me where exactly I’m right or wrong on all that. 48.39 ROBIN TROWER – Bluebird – Robin Trower, 12″ EP – Chrysalis – 1977 With a lot more guitar here than is usually found on 41 Rooms, for me with any Robin Trower I heard back in the day it was always Jimmy Dewar’s vocals that I took to. 54.07 KELELA – Idea 1 – Download only – Warp – 2026 A wash of a sound from the decade-long Warp label artist. 57.23 CALLERS – Young People – Life Of Love, LP – Western Vinyl – 2010 Dark Folk, I reckon. When Sara Lucas’ vocal gets earthy and ‘gutteral’ and let’s loose. It’s a switch that used to get me with Liz Fraser, though her ‘switch’ sounded more polarised. 01.01.01 THIS MORTAL COIL – Strength Of Strings – Filigree & Shadow, 2LP – 4AD – 1986 The first of two times vocalist Dominic Appleton fronted TMC, and I have to admit that I got the title wrong on the show. So, without time to correct it you got no title and I’d have better gotten away with it (or sounded less vague?) if there hadn’t been twenty five TMC tracks on the release, all with different personnel involved. Sod’s Law. 01.05.11 DRY CLEANING – Sliced By A Fingernail – Download only – 4AD – 2026 And from the 4AD label in 1986… to their 2026 output and I’d be slight wary of anybody saying ‘Happy birthday’ in this tone to me. 01.09.10 GNAG OF FOUR – He’d Send In The Army – Solid Gold, LP – EMI – 1981 Always saying it like they saw it. 01.12.56 YOUNG MARBLE GIANTS – Cakewalking – Final Day, 7″ – Rough Trade – 1980 In a most understated manner they sort of made a statement when they appeared on BBC 2’s Something Else in late ’80. 01.15.42 OSCAR FARRELL – Tripping Up In A Rush – I’ve Already Called, 12″ EP – dh2 – 2025 I might have to keep an eye and ear on this chap. 01.18.40 CABARET VOLTAIRE – Sleepwalking (John Peel session track, 1984) – Radiation (BBC Recordings 84-86), LP – Get Back – 2001 Having earlier been Cakewalking, now we’re Sleepwalking. All part of the service. Though actually released three years earlier (but only on CD) the above Get Back-label vinyl release has been followed up in 2026 by a bootleg version. The people dictate… and I’ll be with them catching the very last CV gigs ever, near the end of the year. 01.24.03 GIFT – Pinkhouse Secret Rave (Redux) – Download only – Self-released – 2026 A track from their 2022 debut album, Momentary Presence given a 2026 rework/remix, sorry ‘Redux’ and according to Discogs there are at least 33 acts called Gift! In this day and age – what with both the clamber for attention and the availability of info out there – you’d think… 01.28.16 GANZHEIT – Bolt It Down (Why Work?) * – Summer Of ’84 (demo cassette only) – Self-released – 1984 Out of Bedford. Clattering and driving punk electronic stuff. From the same time-frame, this one reminding a bit of Portion Control, a band who’d played the town earlier in the year above. 01.34.21 SUPER EXTRA BONUS PARTY (feat SORCA McGRATH) – Some Dark Forces – LovesVinyl Issue 02, v/artist 12″ – LovesVinyl – 2019 Ex-Ships vocalist sails over a Running Up The Hill-like drum pattern. 01.38.30 TRACEY THORN – Easy – Out Of The Woods, LP – Virgin – 2007 On the quieter side, One of the ‘signature’ voices, 01.41.49 BETH HIRSCH – Miner’s Son (Aquatic Mix) – 10″ – Artefact – 1997 Bang Bang’s mix sets Beth back a bit in the mix but if lesser known than Ms Thorn above, it’s yet another signature voice. 01.46.43 JONI MITCHELL – Song For Sharon – Hejira, LP – Asylum – 1976 Epic storytelling in a single song. 01.54.46 WAR (feat JOSE FELICIANO) – East L.A. – Peace Sign, 2LP – Avenue – 1994 This show had to be totally put together on the fly, between daily meet ups with friends back in Bedford and London, but the weather was brill right through and the piecing together ended up in the Leytonstone sunshine… even though that’s nowhere near East L.A. There’s a longer, more up front vocals version of the song where Jose also takes on the verses and given my JF leanings I could have placed that one here, but I actually like him ‘countering’ to War vocalist, Lonnie Jordan. Everything about Jose’s vocal when he first drops in here is why I first loved the man back in the late 60’s/early ’70s. I once reminded Jose of the track’s two versions and also (importantly) why I liked this one more… and maybe understandably he seemed a bit disappointed. Show 152 will be here June 7. Dec x The post Post Punk Plus Podcast Playlist 151 – Original upload 3.5.26 appeared first on 41Rooms.

Borgcast Galactica
BabylOrg 5 1.23- web splooge

Borgcast Galactica

Play Episode Listen Later May 2, 2026 53:32


Anne-Marie and Peter finish Babylon 5 S1, covering Chrysalis. The Babylon 5 theme was written by Christopher Franke. All music included is for illustrative purposes only, and no copyright infringement is intended. The artwork for BablyOrg 5 was by Quinn Organ. Following a break for medical attention, on the 28th May the Orgs start season 2 by covering Chrysalis. Feel free to send your thoughts in (just keep the feedback to less than 5 minutes please). Borgcast@gmail.com

REAL PARANORMAL ACTIVITY - THE PODCAST/NETWORK
(VIDEO) ENTERTAINING SHORT FILMS: THE CHRYSALIS (HORROR)

REAL PARANORMAL ACTIVITY - THE PODCAST/NETWORK

Play Episode Listen Later May 1, 2026 9:22


ENTERTAINING SHORT FILMS is a new category on the RPA Network, which features indie short films for your enjoyment! We applaud these creators! A young man moves in with his mother, a retired entomologist, now suffering from dementia. But he soon begins to suspect her altered behavior indicates something more insidious at play.

StaR Coach Show
490: AI: A Coach's Ultimate Thought Partner with Ron West, PCC

StaR Coach Show

Play Episode Listen Later Apr 29, 2026 49:06


AI is all around us! Is it a threat or an opportunity? How do coaches make sure to stay in the driver's seat and engage with AI in an ethical, yet productive way? The bottom line is that AI can serve as a powerful multiplier for coaches—not a replacement for them. You'll learn how today's guest leverages the power of AI in various ways to organize his life's work and enhance client deliverables. His enthusiasm for AI is balanced by practical caution, emphasizing that the coach must always be the one “driving the bus.” Join us to learn more!Ron J. West is an executive coach and the founder of West Executive. For more than two decades, he has worked with senior leaders navigating complexity and change. He is the creator of the Chrysalis ecosystem, which comprises leadership experiences built around a simple idea: when leaders expand how they think and lead, the organizations and systems they serve can also evolve. Ron is a repeat guest on the STaR Coach Show, and we're thrilled to visit with him again!Show Highlights:AI as a useful thought partner–not a replacement for coachesRon's brainchild project: building a captured/private GPT of his body of work of 600+ artifacts (the Chrysalis AI Portal)Establishing guardrails to keep AI private and controlled (I.e., captured–as opposed to “set free” on the internet)Using Chrysalis as a practitioner with clear guidelines and purpose (“What am I trying to achieve?”)When using AI, remember who is “driving the bus”!Examples from Ron and Meg of using AI in the coaching processAI cannot replace the human aspect of coaching—in meeting people where they are.Compiling a database with the help of AI to build your legacyExamples of infographics and other resources created by AIRon's advice to coaches about harnessing the power of AI: “Just experiment. Enjoy the journey!”Resources:Connect with Ron WestLinkedIn and ChrysalisConnect with MegExplore the STaR Coach Show Mentor Program. We are enrolling NOW for this summer!Subscribe to the STaR Coach Show YouTube Channel!Explore over 480 past episodes and other helpful resources at www.STaRcoachshow.com.Mentioned in this episode:Enroll More Clients: Clarity SprintDo you love coaching, but when it comes to enrolling clients, writing your bio, or posting online, you freeze? Or fall into “coach speak” that doesn't actually connect? That's not a you problem. It's a messaging problem—and it's costing you clients. Join me for my free, live five-day experience: Enroll More Clients: Clarity Sprint. From March 16–20 at 9 a.m. Central, I'll help you get crystal clear on your ideal client, refine your message so it actually resonates, and create a confidence statement that makes booking a call the obvious next step. No fluff, just clarity, you can use immediately. Grab your free spot at: https://starcoachshow.com/5dayEnroll More Clients: Clarity Sprint

Strange New Worlds: A Science & Star Trek Podcast
Episode 197: The End of Everything

Strange New Worlds: A Science & Star Trek Podcast

Play Episode Listen Later Apr 19, 2026 45:50


Guest: Dr. Katie Mack Cosmologist Katie Mack beams aboard to discuss how the universe will end. Using the Star Trek: Deep Space Nine episode "Chrysalis" as a launchpad, Katie and Mike go through various scenarios for the fate of everything: Will there be a "big crunch," a "big rip," or will it all simmer away into "heat death"? And is there anything we can do about it? "The End of Everything (Astrophysically Speaking)" by Katie Mack: https://www.simonandschuster.com/books/The-End-of-Everything/Katie-Mack/9781982103552 Follow us on Bluesky! Mike: https://bsky.app/profile/miquai.bsky.social Katie: https://bsky.app/profile/astrokatie.com

Borgcast Galactica
BabylOrg 5 1.22- Alien wang designer

Borgcast Galactica

Play Episode Listen Later Apr 18, 2026 53:11


Anne-Marie and Peter continue their journey through Babylon 5 S1 covering The Quality Of Mercy. The Babylon 5 theme was written by Christopher Franke. All music included is for illustrative purposes only, and no copyright infringement is intended. The artwork for BablyOrg 5 was by Quinn Organ. On the 30th April the Orgs finish season 1 by covering Chrysalis. Feel free to send your thoughts in (just keep the feedback to less than 5 minutes please). Borgcast@gmail.com

Solidarity Breakfast
Headlines II Voices4Palestine II Chrysalis Exhibition II This is the Week II National Wage Case II

Solidarity Breakfast

Play Episode Listen Later Apr 3, 2026


Headlines here II Update on US/Israel War on Iran/ Interesting labour news from US from Payday - Unite Here workers refuse to work hotels or stadiums that house ICE operatives/ Navy Shipyard worker strike/ Major win for guest workers targeted for wage theft/ Duterte in front of International CourtVoices4Palestine here II Josh Lees and Yamin from Palestine Action and students for Palestine then NSW MP Sue Higginson speaking at the Hands off Iran rally held in Sydney 30/3/2026 Recorded by Vivian Langford 3crClimate Action Show Mon 5pmChrysalis Exhibition here II We speak with Lachlan Plain - Artist about his exhibition Chrysalis an immersive exhibition and film project exploring metamorphosis through oil-on-glass, animation, sculpture and music. Presented with Melbourne International Animation Festival and Banyule City Council. Chrysalis Exhibition Opening 9th April - 10th MayLoft 275 Ivanhoe Library and Culture Hub 275 Upper Heidelberg Rd Ivanhoe.This is the Week here II Kevin Healy combs through the week with satire.National Wage Case here II Don Sutherland talks about the National Wages Case when there is a resetting of the rate paid to the lowest paid workers in Australia.

The Money Trench - The Music Industry Podcast with Mark Sutherland
TMT:83 Jeremy Lascelles On Building A Game-Changing Indie Music Company

The Money Trench - The Music Industry Podcast with Mark Sutherland

Play Episode Listen Later Mar 23, 2026 61:05


Welcome to The Money Trench! This week, Mark is joined by Jeremy Lascelles, Co-founder and CEO of Blue Raincoat Music. Having been a manager, tour manager, and a key figure at renowned indie companies Virgin and Chrysalis, Jeremy has had the unique opportunity to work with a wide range of artists. The pair discuss his career, the evolution of Blue Raincoat into a hybrid music company, and his thoughts on the current state of the independent sector. NEWSLETTER ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sign up HERE⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the TMT newsletter - featuring each week's hottest music industry stories. SOUNDON The Money Trench is sponsored by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SoundOn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. TIXEL The Money Trench is sponsored by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Tixel⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. PPL  The Money Trench is sponsored by the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PPL⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. KEEP UP TO DATE For the latest podcast and music business updates, make sure to follow us on:  Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@the_money_trench⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Money Trench⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Money Trench⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ GET IN TOUCH If you have any feedback, guest suggestions or general comments? We'd love to hear from you! -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in touch here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Thanks to our partners ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SoundOn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Tixel⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PPL ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Earth/Percent⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Tom A Smith⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Aimless Play⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fourth Pillar⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sennheiser⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Junkhead Studio⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Tape Notes⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Executive Producer: Mike Walsh Producer: Tape Notes 

ASCO Daily News
Navigating Therapeutic Advances in EGFR-Mutated NSCLC

ASCO Daily News

Play Episode Listen Later Mar 19, 2026 19:24


Dr. Monty Pal and Dr. Vamsi Velcheti discuss the evolving treatment landscape in EGFR-mutated non-small cell lung cancer, including landmark trials like FLAURA2, novel drug therapies, and the growing importance of ctDNA and MRD testing. TRANSCRIPT Dr. Monty Pal: Hello, and welcome to the ASCO Daily News Podcast. I'm your host, Dr. Monty Pal. I'm a medical oncologist and professor and vice chair of academic affairs at the City of Hope Comprehensive Cancer Center in Los Angeles. Today, I'm truly delighted to introduce Dr. Vamsi Velcheti, who's a professor of medicine and the chief of hematology-oncology at the Mayo Clinic in Jacksonville, Florida. We'll be discussing the expanding treatment landscape in EGFR-positive lung cancer and how to navigate the challenges of balancing treatment efficacy, toxicity, and patient quality of life in the EGFR-positive space.  Just FYI, our full disclosures are available in the transcript of this episode.  Vamsi, it's so great to have you on the podcast. Thank you so much for being here. Dr. Vamsi Velcheti: Thank you, Monty. It's a pleasure to be here with you. It's a really exciting topic and there are a lot of updates in the EGFR space. Dr. Monty Pal: So, I'm going to need your help with this because I'll be honest with you, I see very little lung cancer, if any, in my practice. I'm pretty much exclusively kidney cancer these days. I'm coming on 20 years at City of Hope now, and I still remember when trials like ECOG 1599 were presented with, you know, platinum doublets. And, of course, the field has changed a lot since then. But tell us a little bit about the first-line landscape, and I think just for the sake of time, we're going to stick with EGFR-positive disease here. What does it look like these days? Dr. Vamsi Velcheti: Monty, the foundation of care remains the third-generation EGFR inhibitors. These are selective EGFR inhibitors, like osimertinib. We've had an evolution of the development of these TKIs. Like, you know, we had the first-generation, second-generation, not-so-selective EGFR inhibitors. Now we have mutant-selective EGFR inhibitors in the clinic, and they're doing a really good job. And these are quite effective in patients who have classical activating mutations. But the reality is that these have not been transformative. These agents have fundamentally changed the response patterns, excellent CNS penetration, and very good tolerability profile. However, we don't see a lot of durability in terms of the response. So, what's different today is now there have been several trials in combination with these third-generation EGFR inhibitors that have really laid the foundation of how we kind of think about EGFR-positive disease. At the high level, there are a lot of challenges to selecting the patients for these combination-based modalities. I'm assuming we'll be talking more about these different trials and different approaches. Some of these combination-based strategies have really moved the needle in terms of improving overall survival and really improving long-term outcomes and durability in our patients. Dr. Monty Pal: And we are going to get into the weeds on this in just a moment. But I did kick off this podcast talking about chemotherapy, ECOG 1599. It does seem as though chemotherapy is still a component of management in advanced non-small cell lung cancer. So, can you tell us about, perhaps first, you mentioned osimertinib, you know, some of these next-generation EGFR inhibitors. Tell us about the role of chemo plus osimertinib. Dr. Vamsi Velcheti: That's exactly where I was going with the combination-based strategies. You know, we first started off with our earlier trials in the EGFR space evaluating the question of, are targeted therapies, are these highly effective, third-generation, EGFR-selective inhibitors, superior to platinum-doublet chemotherapy? And we've had multiple trials demonstrating that, like the FLAURA trial and in the past with second-generation EGFR inhibitors like erlotinib and gefitinib and afatinib. So, we know that these TKIs actually perform better than platinum-doublet chemotherapy. Now, we have a large, global, phase 3 trial data from the FLAURA2 trial, which looks at the question, "Hey, you know, osimertinib is better than chemotherapy, platinum-doublet chemotherapy. Can we do even better by combining osimertinib with platinum-doublet chemotherapy?" So, FLAURA2 answered that question. This is a large, phase 3 trial, and it's a positive trial with improved durability of disease control and improving overall survival with combination with chemotherapy. So, it's a very important and landmark trial, and essentially combining osimertinib with a platinum-based chemotherapy improved responses, deepened responses, and improved overall survival and really changing the disease trajectory. And this strategy is definitely compelling, especially in patients who have certain clinical high-risk features like, you know, patients who have high disease burden or patients who are sometimes having rapid disease progression early on osimertinib, especially with patients who have a lot of visceral disease burden. So, intensifying treatments up front could alter the natural trajectory of the disease. Dr. Monty Pal: So, you sort of alluded to this in that last part there, but is that kind of how you in clinical practice select? Is it based on, you know, visceral involvement? Is it based on rapidity of disease where you think about adding chemotherapy to osimertinib? Maybe you can give us the corollary. Which patients do you just use osimertinib alone in, for instance? Dr. Vamsi Velcheti: Definitely, there are some patients who have low disease burden and they have the classical mutations, like an exon 19 deletion. And these patients, especially if they don't have a lot of disease burden, they don't have CNS involvement, there may be a subset of patients who could just do fine on osimertinib of course, with close monitoring of the disease. I guess we'll get into that later, how do we do that with either ctDNA or like closer imaging or both. So, there may be some opportunity to kind of escalate patients' treatments based on certain clinical characteristics or radiographic characteristics or certain biological characteristics informed by ctDNA or other approaches. Dr. Monty Pal: No, that's interesting. And you're right, we will chat about ctDNA in just a bit. But before we get there, I think one of the big agents that has really sort of come to the fore in advanced non-small cell lung cancer is amivantamab. I've heard a lot about this in the context of even kidney cancer because in certain subsets, I'm interested in MET-directed therapies and so forth, right? So maybe tell us a little bit about the mechanism of amivantamab first, and then maybe tell us about this pivotal MARIPOSA trial where it's combined with lazertinib. Dr. Vamsi Velcheti: So, the MARIPOSA trial compared lazertinib alone with amivantamab plus lazertinib. And this trial demonstrated overall survival advantage, and there were key differences in terms of tolerability and the safety of amivantamab, which is an EGFR and MET bispecific, and there were certain kind of unique toxicity profiles that make it a little different than the intensification approach with chemotherapy through the FLAURA2 trial. So, there's a trade-off in terms of the toxicity profile. It's a different agent and a different management protocol in terms of dermatological toxicity management that clinicians need to be comfortable with. And also, there are certain unique issues in terms of amivantamab; there's a higher rate of infusion-related reactions, there's an increased risk for edema and VTEs because of amivantamab. Certainly a different toxicity profile, different management paradigm there in terms of longitudinal care of these patients requiring dermatological care and like, you know, close monitoring and prophylaxis VTEs. But having said that, definitely it's a different strategy, and it kind of changes the biology and the natural history of the cancers, and we do see some durability of responses that we see with the MARIPOSA. So, it's certainly a great alternative, at least for some patients. Dr. Monty Pal: That was a great overview of MARIPOSA. Now comes the really difficult question, which is, how do you choose between the two? You have these two great options, right, for EGFR-positive patients. You've already highlighted some of the distinctions in terms of toxicity. I think the audience is well aware of the side effects of chemo-doublet, perhaps even the EGFR-based therapies. Amivantamab is quite new. Give us a sense of how you in clinical practice decide between the two potential options here. Dr. Vamsi Velcheti: Yeah, I think that's the big challenge. I think these are two independent strategies that have evolved through the phase 3, and both of them have demonstrated overall survival benefit. So, the way I think about this is in three dimensions, right? Like, the disease biology, the patient priorities, and feasibility of care delivery. So, when I talk about the disease biology, you know, the mechanism is very different, and MET is a very dominant driver of disease in EGFR-altered patients and it's a significant mechanism of resistance, acquired resistance to TKIs. So, certainly I think there's a patient population that could benefit from a MET-directed therapy up front. However, we don't have great data to kind of really demonstrate how using amivantamab in the front line is going to change that. And are there like perhaps like some patients who we could identify who would benefit from such a strategy? Very recently, there have been some approvals in the second-line setting in lung cancer, not in the EGFR space, but like in generally in lung cancer, with the MET ADCs, and those drugs are approved with a companion diagnostic, which requires MET IHC testing. So, what has happened, at least in large academic practices and also I think in the community now, they have been checking for MET IHC expression more routinely in lung cancer. What we have been doing in our institution is we have been doing MET IHC as a reflex for all patients with EGFR, not just EGFR, but all non-small cell lung cancer patients. What that has done is now, like, we have been increasingly testing patients with EGFR for MET. And there's clearly a subset of patients who have de novo MET expression and a high MET expression. And those patients, I've been kind of like preferentially treating them with the MARIPOSA regimen. But again, I have to caution the audience that we still don't have data that MET IHC is going to help us make those decisions, whether it's better than like a FLAURA2 regimen. But however, in the second-line setting in the CHRYSALIS trial, we know that MET is a very powerful predictor of response to amivantamab. We really need more data there, but that's what I have been doing in my practice. But also, there's a lot of patient preference here. Like, there are some patients who don't want chemotherapy, and they want a non-chemotherapy approach. So, certainly there are some patients who prefer to have amivantamab. And now with the amivantamab, the subcutaneous version, the infusion reactions and the logistics of actual administration of amivantamab are more favorable with the subcutaneous approval. So, those are some of the elements that we need to take into account. Dr. Monty Pal: Well, I want to hone in on that because this subcutaneous administration route has been a big debate that I've seen on social media. Tell us, how much easier does it actually make the amivantamab experience? Does it cut down on the rash? Is it just infusion reactions? What's been your clinical experience? Vamsi Velcheti, MD: So, the subcutaneous administration of amivantamab has definitely improved the infusion reaction issue. Very rarely patients have infusion reaction now with the subcutaneous injections. And also, the infusion time is much, much shorter. Like we don't need a lot of infusion time, which is sometimes a challenge in busy infusion clinics. We need to take that into account. As far as the impact of the subcutaneous formulation on dermatological toxicity, we haven't really seen significant difference in terms of the intensity or rates of dermatological toxicity with subcutaneous. The benefits are really with the infusion reaction, the ease of administration. And interestingly, in the PALOMA trial, it also seems to be, even though this was not the primary endpoint of the study, there seems to be some suggestion that the subcutaneous amivantamab seems to have improved OS compared to the IV amivantamab. We don't really understand why, but that's a finding from the trial that's very intriguing. Dr. Monty Pal: That is really fascinating. I'm kind of curious to see how that's going to pan out. I'm going to shift gears a little bit here. And, you know, as we sort of close, I wanted to talk a little bit about biomarkers. I mean, this is obviously not a lung cancer-specific issue. It's something we think about across the board. But what I will say is that there are certain commonalities, and in bladder cancer, we think a lot now about ctDNA. But you've been way ahead of the game in lung cancer. Tell us how you guys use ctDNA, maybe both from the standpoint of monitoring for mutational status, but if you can, maybe offer some insights into some of these new MRD tests that are available too. Dr. Vamsi Velcheti: Yeah, it's rapidly evolving. Certainly, I think in the lung cancer space, you know, this has really kicked off in the lung cancer space with incorporating ctDNA into the workflow. Of course, you know, like baseline evaluation, we still kind of heavily rely on tissue genomic sequencing. But as you know, with targeted therapy, a lot of these patients have disease that evolves over time, and changes in terms of mutational pattern driving acquired resistance is a major issue across different molecular subtypes. And especially so in EGFR, when there are certain actionable opportunities associated with that transformation. So, we need to kind of have like a longitudinal snapshot of how we monitor these patients. So, the ctDNA has come to be like a tool that has now come to the forefront of clinical workflow, and almost all my patients who are having disease progression have ctDNA for kind of evaluating for resistance and informing treatment decisions, especially in EGFR. But having said that, there are a lot of challenges in terms of using ctDNA as a tool for monitoring. There are a lot of different types of assays and different platforms, and being able to use this as a quantitative tool that would be used along with the CT scans that we routinely use in clinical practice has been a challenge. And I think I would love to hear your perspectives as well, Monty, about how you're thinking about that in bladder and other disease contexts. But having said that, I think there's a lot of opportunity to incorporate ctDNA and MRD assays into clinical decision-making. Right now, in terms of clinical trials and clinical development, there have been some very interesting trials that are currently ongoing, especially in the EGFR space. We know that patients who clear ctDNA, based on some retrospective data and also like some retrospective-prospective data from trials that have already read out, that patients who clear ctDNA early with target therapy tend to do much better. They have a longer durability of response. There may be a subset of patients who have, even though they're having radiographic response, they have persistent ctDNA after a certain time point of initiation of targeted therapy. Those patients may require escalation of therapy. We don't yet know. I can't recommend that as a standard right now because we don't have clinical evidence to support that. But however, some of the clinical trials, like the ELIOS trial that's being done right now, that's actually completed enrollment, we'll hopefully see the results very soon. So, there is an emerging thought that instead of intensifying treatment for all patients with EGFR, there may be a population that may be just fine with frontline osimertinib monotherapy and introducing the intensification strategy at the time of emergence of MRD or progression on ctDNA before radiographic progression. So, there are a lot of adaptive molecular response criteria that we are kind of exploring in clinical trials that could inform how the future is going to look like for EGFR and other perhaps targeted therapies as well. So, it's fascinating, and I think there's a lot of opportunity there. Dr. Monty Pal: You know, you asked for my perspective. I actually think that what you highlighted there is the most interesting opportunity for ctDNA: the ability to de-escalate therapy. In terms of drug development, we've done so much to bring new therapies to patients, and now it's a bit of an embarrassment of riches, but the downside is that I feel like we tend to overtreat a lot of patients in the clinic. So, I definitely view MRD, you know, some of these other ctDNA techniques with methylation and so forth that may not be sort of tumor-dependent or bespoke could be incredibly, incredibly helpful. You touched on sort of the future, right, in this last section here with biomarkers. But give us a sense now in terms of novel drug therapies in the EGFR space. What are you most excited about moving forward in 2026 and beyond? Dr. Vamsi Velcheti: Yeah, I think there's a lot going on in this space, and not just this space, but across lung cancer and others as well. Like looking at the next generation of targets for ADCs. And I think a lot of these have to do with…so far in the drug development space, as you know, the improvements in clinical outcomes has been very incremental. So, we really need to make that big leap. And I think the big leap is not going to come from, in my opinion, from the next ADC, but it's going to come from how we tailor treatments and how we monitor disease better and how do we kind of incorporate the next treatment earlier and not wait for the radiographic progression. So, there's a lot of opportunity there to integrate biomarkers and dynamic biomarkers into clinical trial design and incorporating the recent advances in terms of drug design. You know, we have a lot of assets in the EGFR space, the next-generation EGFR inhibitors that are kind of designed with resistance in mind and rational combination, knowing when to introduce those combinations is also equally important. So, there's a lot going on, really exciting times to be in drug development. The one thing that I really hope will come to the forefront in drug development, not just for lung cancer, but all disease groups, is to kind of really be thoughtful about how we incorporate these really cool molecular monitoring tools and creating a composite score with imaging to be able to like really design the next generation of clinical trials. Dr. Monty Pal: You're so spot-on with that. I definitely think that we're getting to this point where, you know, we could think about the next BiTE, the next CAR-T, the next ADC. But, you know, maybe it's time for us to start really honing in on appropriate applications of these drugs, honing in on the right dose and what have you, because I definitely see some issues there.  Vamsi, this has just been terrific. I really want to thank you so much for sharing your fantastic insights with us today on the ASCO Daily News Podcast, and I really appreciate all your efforts to move the field of lung cancer forward. Dr. Vamsi Velcheti: Thanks, Monty. I really enjoyed the conversation. Dr. Monty Pal: Yeah, this was terrific.  And thanks to our listeners as well. If you value the insights that you hear from the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Follow today's speakers:     Dr. Monty Pal   @montypal  Dr. Vamsi Velcheti @VamsiVelcheti Follow ASCO on social media:          ASCO on X    ASCO on Bluesky         ASCO on Facebook          ASCO on LinkedIn          Disclosures:       Dr. Monty Pal:      Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview     Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical     Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis   Dr. Vamsi Velcheti:   Honoraria: Galvanize Therapeutics  Consulting or Advisory Role: Bristol-Myers Squibb, Merck, AstraZeneca/MedImmune, GSK, Amgen, Taiho Oncology, Novocure, Regeneron, Takeda, Janssen Oncology, Picture Health Research Funding (Inst.): Genentech, Trovagene, Eisai, OncoPlex Diagnostics, Alkermes, NantOmics, Genoptix, Altor BioScience, Merck, Bristol-Myers Squibb, Atreca, Heat Biologics, Leap Therapeutics, RSIP Vision, GlaxoSmithKline

In The Author's Voice
In The Author's Voice: The Chrysalis Option

In The Author's Voice

Play Episode Listen Later Mar 12, 2026 5:59


In this edition of In The Author's Voice, author and SIU Law School alum Eric Coulson talks about his novel "The Chrysalis Option."

Das Universum
DU151 - Die Zerstörung von Welten und die Entstehung der Saturnringe

Das Universum

Play Episode Listen Later Mar 10, 2026 91:09 Transcription Available


In Folge 151 klären wir, warum die Ringe des Saturns nichts mit der Vorhaut von Jesus zu tun haben, sondern mit der Zerstörung von Monden. Evi erzählt uns, was Luke Skywalker als Buchhalter zur Mathematik zu sagen hat und wir sind von Bestsellerlisten irritiert. Wenn ihr uns unterstützen wollt, könnt ihr das hier tun: https://www.paypal.com/paypalme/PodcastDasUniversum Oder hier: https://steadyhq.com/de/dasuniversum Oder hier: https://www.patreon.com/dasuniversum

Big Sky Astrology Podcast
333 | Aquarius New Moon Solar Eclipse: Emerging from the Chrysalis!

Big Sky Astrology Podcast

Play Episode Listen Later Feb 16, 2026 27:36


This week: Mercury trines Jupiter, and it's a good time to open up your mind and let everything spill out. An Aquarius New Moon Solar Eclipse is the first eclipse in that sign since 2018, and it is time for a change. Venus and Jupiter bring a peaceful moment in a busy week. And the Sun enters peaceful Pisces just a couple of days before the transit that astrologers have been talking about for ages, the Saturn-Neptune conjunction at zero degrees Aries. It's another busy week in the Big Sky, so we will have to wait and answer a listener question next week! Plus: Building a dream, an inverted funnel, and shifting borders! Read a full transcript of this episode. Have a question you'd like answered on the show? Email April or leave it here! Subscribe to April's mailing list and get a free lunar workbook at each New Moon! Love the show? Make a donation! Timestamps [1:37] Mercury trine Jupiter (Feb. 16, 1:31 pm PST) at 15°53' Pisces and Cancer. The Sabian symbol for Mercury is 16 Pisces, The flow of inspiration. Jupiter's Sabian symbol is 16 Cancer, A man before a square with a manuscript roll before him. Make a conscious effort to stay curious, open, and inspired. [4:04] Moon Report! Aquarius New Moon Solar Eclipse (Feb. 17, 4:01 am PST) at 28°49' Aquarius, at 29 Aquarius, A butterfly emerging from a chrysalis. Today also marks Chinese New Year and the year of the Fire Horse! Courage, clarity, and willingness to move forward will be our guides in the year ahead. [9:07] This is the New Moon in a Lunar Phase Family Cycle (LPFC) that unfolds over the coming three years. The First Quarter Moon (first action point) of this LPFC is on Nov 17, 2026 (25°8' Aquarius). The Full Moon Lunar Eclipse (awareness point) is on Aug 17, 2027 (24°11') Aquarius. The Last Quarter Moon (last action phase) is on May 16, 2028, at 26°5' Aquarius. [11:06] Void-of-Course (VOC) Moon periods. The Moon in Aquarius makes its New Moon conjunction with the Sun (Feb. 17, 4:01 am PST). It's VOC for 2 hours 8 minutes, then enters Pisces (6:09 am PST). Meditate on how you can contribute to the betterment of all. [11:57] The Moon in Pisces sextiles Uranus in Taurus (Feb. 19, 7:23 am PST). It's VOC for 4 hours 16 minutes, then enters Aries (11:39 am PST). Gather the courage to speak your mind. [12:51] The Moon in Aries sextiles Mars in Aquarius (Feb. 21, 3:11 am PST). It's VOC for 12 hours and 20 minutes, then enters Taurus (3:31 pm PST). Sweat out your frustrations. [14:15] Sun enters Pisces (Feb. 18, 7:52 am PST). The Sabian symbol for the Sun's ingress into Pisces is 1 Pisces, A public market. The Sun will stay in Pisces until March 20, 2026. The invitation is to participate in the world with sensitivity and intention. [17:50] Saturn conjoins Neptune (Feb. 20, 8:54 am PST) at 0°45' Aries. The Sabian symbol for this degree, 1 Aries, is A woman rises out of the water, a seal rises and embraces her. This conjunction takes place on a world point, so its effects tend to show up not just personally, but collectively. Saturn and Neptune come together about every 36 years, and when they do, we see the dissolution of borders and structures, leaks and scandals, major spiritual or creative shifts. What we commit to now will shape an entirely new reality. [21:12] Venus trine Jupiter (Feb. 22, 12:02 pm PST) at 15°31' Pisces and Cancer. Venus' Sabian symbol is 16 Pisces, The flow of inspiration. Jupiter's Sabian symbol is 16 Cancer, A man before a square with a manuscript roll before him. The real gift of this transit is contentment, the kind that comes from really knowing yourself and choosing pleasure with intention. [24:06] Unfortunately, there was too much to cover in this week's sky for a Listener Question. Keep those questions coming in, though! Leave a message of one minute or less at speakpipe.com/bigskyastrologypodcast or email april (at) bigskyastrology (dot) com; put “Podcast Question” in the subject line. Free ways to support the podcast: subscribe, like, review and share with a friend! [24:48] A tribute to this week's donors! If you would like to support the show and receive access to April's special donors-only videos, go to BigSkyAstropod.com and contribute $10 or more. You can make a one-time donation in any amount or become an ongoing monthly contributor.

Recording & Mixing
Advanced DAW Automation

Recording & Mixing

Play Episode Listen Later Feb 12, 2026 20:48


Eddie Bazil demonstrates creative uses of advanced automation as a musical tool in the DAW, showing how automation can add movement, expression and musical detail. The episode covers shaping arpeggiated parts, using MIDI CC for dynamic control, modulating vocal tracks and applying MIDI note expression to enhance performance.Chapters00:00 - Introduction01:49 - Setting Up Automation Lanes02:30 - Example 1: Adding ARP Movement04:51 - Example 2: Using MIDI CC For Velocity07:41 - Example 3: Modulating A Vocal Track 14:52 - Example 4: MIDI Note Expression In A DAW #gforce #imposcar3 #cubase #deviousmachines #infiltrator2 #cableguys #shaperbox #ovoxvocoder #eventide #blackholeSee Also:https://www.soundonsound.com/techniques/using-phaser-effects-podcast Eddie Bazil BiogEddie Bazil launched his music industry career at the age of 17 as a synth programmer for a range of Electro / New Wave bands, including Art Of Noise, Spandau Ballet, Pet Shop Boys, Bobin, Paul Dee, DJ Krush, DJ Shadow, Jets Orchestra, and many more. By his 20s, he was working as a sound designer for Akai, Roland, Emu/Ensoniq, eventually signing on exclusively with the latter. Later, due to a growing demand for software instruments and libraries, Eddie began developing libraries for various software manufacturers, including Native Instruments, Kiesel, Sound Effects Library, Rob Papen, Arturia, and Propellerheads.During this time, he trained in music production. He soon gained several prominent contracts working with some notable artistes such as Busta Rhymes, Greensleeves, 9 Bar, SFP, Sleeveless, Chris Campbell and Gam Productions. He contracted to Island Records and Chrysalis as a producer and remixer, and was commissioned to write the score for Macbeth that ran at 2 Way Mirror at Alexander Palace for the Cambridge Shakespeare Company. This led to him offering educational workshops and classes, and becoming a contributing creator and Forum moderator for Sound On Sound.Recently, he was invited by the Recording Academy to become a professional member, approved educator, and mentor for their member base. Eddie now concentrates on providing private sound design and mixing/production tuition, and creating content for Sound On Sound magazine.https://eddiebazil.co.uk/Catch more shows on our other podcast channels: https://www.soundonsound.com/sos-podcasts

Moonlight Audio Theatre
RETRO ROCKETS PRESENTS: Chrysalis

Moonlight Audio Theatre

Play Episode Listen Later Feb 8, 2026 48:44


Sonic Cinema Productions: Retro Rockets, "Chrysalis" by Jack Ward 86 years after Orson Welles' radio drama changing event, this 2024 World Audio Drama Day production fires off a Retro Rockets special with "Chrysalis". Scientist Joe meets up with old flame Ana, a journalist, as they and a few others team up to discover what strange object fell from the Martian skies, to land at Stoney Creek!

Weirdly Magical with Jen and Lou - Astrology - Numerology - Weird Magic - Akashic Records

Louise Edington discusses the upcoming solar eclipse on February 17, an annular eclipse visible over Antarctica, and its significant impact on personal and collective life shifts. She explains that solar eclipses act as cosmic catalysts for new beginnings and major life changes. The eclipse is at 28 degrees Aquarius, marking the sixth of seven new moons at this degree, symbolizing powerful leadership and new beginnings. Key aspects include a square to Uranus and the emergence of Venus as the evening star. Additionally, Louise highlights the Saturn-Neptune conjunction at zero Aries, a rare event occurring after over 6,300 years, signaling a new astrological age.Useful linkshttps://docs.google.com/document/d/1E4wl_i0VKPwTeeBangBcCBZCcfzhVxPOORXRVvvZuiY/edit?usp=sharingWelcome to Cosmic Owl Astrology

Incredible Life Creator with Dr. Kimberley Linert
Over 50? Learn AI With Ease - Guy Gane Ep 622

Incredible Life Creator with Dr. Kimberley Linert

Play Episode Listen Later Feb 6, 2026 31:53


Guy W. Gane, Jr. built a distinguished career spanning over 30 years in the financial servicesindustry. As a nationally recognized stockbroker and Registered Investment Advisor, he ownedmultiple offices across the country, earning a reputation for excellence, integrity, and client-focused service. His journey in finance was both rewarding and impactful, marked by decadesof trusted guidance and strategic expertise.Guy has made his mark with appearances on national television and a five-year run as the hostof his own radio show. Today, he continues to inspire through countless national andinternational podcast features, where he shares powerful messages of resilience, persistence,and success. With every story, he encourages listeners to hold tight to their dreams and neverstop believing in what's possible.Guy, founder of Gane Wisdom, LLC, has built a remarkable portfolio of achievements, includingauthoring three impactful books: Unchained and Unbroken, Chrysalis, and ManagedMoney—each available on Amazon and other major retailers. A sought-after speaker,entrepreneur, and Performance Coach, Guy blends insight with inspiration to help others unlocktheir potential.His latest work, Second Wind: A Graceful Journey into AI Wisdom, explores the transformativepower of Artificial Intelligence in today's world and its profound implications for humanity'sfuture. During his research, Guy uncovered a troubling gap: the lack of accessible AI educationfor individuals over 55. Motivated to change that, he founded the Center for Aging and AIEmpowerment.From this initiative came Second Wind: A Gentle Course into AI Wisdom, an easy-to-followonline program designed specifically for older learners. Free of technical jargon and full ofpractical guidance, it stands as the only AI tutorial tailored to those approaching or enjoyingretirement—quickly earning recognition as a leading resource for this underserved community.Contact Guy Gane:aiacademy@ganewisdom.comacademy.ganewisdom.com.www.linkedin.com/in/guy-w-gane-jr-85b2ab15/www.facebook.com/guy.ganewww.instagram.com/gane_wisdomwww.youtube.com/results?search_query=guy+w+gane+jrwww.instagram.com/aiacademy_creativeagingwww.facebook.com/center for creative aging and ai empowermentDr. Kimberley LinertSpeaker, Author, Broadcaster, Mentor, Trainer, Behavioral OptometristEvent Planners- I am available to speak at your event. Here is my media kit: https://brucemerrinscelebrityspeakers.com/portfolio/dr-kimberley-linert/To book Dr. Linert on your podcast, television show, conference, corporate training or as an expert guest please email her at incrediblelifepodcast@gmail.com or Contact Bruce Merrin at Bruce Merrin's Celebrity Speakers at merrinpr@gmail.com702.256.9199Host of the Podcast Series: Incredible Life Creator PodcastAvailable on...Apple: https://podcasts.apple.com/us/podcast/incredible-life-creator-with-dr-kimberley-linert/id1472641267Spotify: https://open.spotify.com/show/6DZE3EoHfhgcmSkxY1CvKf?si=ebe71549e7474663 and on 9 other podcast platformsAuthor of Book: "Visualizing Happiness in Every Area of Your Life"Get on Amazon: https://amzn.to/4cmTOMwWebsite: https://linktr.ee/DrKimberleyLinertThe Great Discovery eLearning platform: https://thegreatdiscovery.com/kimberleyl

Wisdom from the Earth and Sky with Heather Ensworth, Ph.D.
Overview of the Astrological Energies and Themes of 2026: Emerging from the Chrysalis

Wisdom from the Earth and Sky with Heather Ensworth, Ph.D.

Play Episode Listen Later Jan 15, 2026 56:12


In this podcast, Heather discusses the major astrological energies of 2026 and how we can work with them in the most conscious and effective way possible. Resources: Medicine wheel meditation practice:    • Medicine Wheel meditation for helping us t...   videos about Sedna:    • Sedna: Guiding us through this Time of Tra...  ,    • Sedna and her transits with Uranus and Plu...   Book by Jeffrey Wolf Green: Pluto: The Evolutionary Journey of the Soul, vol. 1 For an evolutionary astrology reading, please go to the Schedule a Session page (under Services) on my website for evolutionary astrologers that I highly recommend. Heather's website: https://www.risingmoonhealingcenter.com/ To become a patron of Heather:   / heatherensworth  

StrangeCast — The Definitive Life Is Strange Fan Podcast
‘GAME OVER!' — The Devastating Blow To Life Is Strange: Double Exposure Studio Deck Nine

StrangeCast — The Definitive Life Is Strange Fan Podcast

Play Episode Listen Later Jan 6, 2026 98:28


Player 1 vs The World's's StrangeCast returns with a full-length episode! ‘Side A' and ‘Side B' will be back in the future. But for now, The Lost Records Journal co-hosts Adnan Riaz and Adam Evalt sit down for a deep dive into a BIG piece of news around Life Is Strange: True Colors and Life Is Strange: Double Exposure developer Deck Nine.

Episode One – 9.2.16
Post Punk Plus Podcast Playlist 146 – Original upload 7.12.25

Episode One – 9.2.16

Play Episode Listen Later Dec 7, 2025 120:08


This playlist is 65% vinyl friendly. Very poor. Scorchio! ‘1960/1970 Vintage Stereo Design Record Player, in bright orange, the emblematic colour of the 1960 and an example of Mod Ultra Space Age Pop Art Raymond Loewy? France French Designer Museum-worthy‘ says the Etsy seller, adding ‘It has a few cracks, one of the speakers has a small tear in the cloth and may need an overhaul, a full check up to see how and if it works and if it is complete… WE HAVE NEVER TRIED TO USE IT AND I DO NOT KNOW IF IT WORKS OR PLAYS.‘ Thank flip it’s down to €4600, from €7100. Any track marked * has been given either a tiny or a slightly larger 41 Rooms tweak/edit/chop and the occasional tune might sound a bit dodgy, quality-wise. On top of that, the switch between different decades and production values never helps in the mix here. And a bit of a croak in my voice here and there. A temporary glitch, hopefully. Lyric of Playlist 146 Trickery involved but it has to be The Bots! 00.00 (Intro) THE FLAMINGOS – Stars (Edit) – Unreleased demo – 1983. Episode #1 for info. 00.41 NEW ORDER – Ruined In A Day (Reading Festival, 1993) – In Concert – 577, CD – BBC Transcription – 1993 I and my four-year-old, Alice were there, on what was a triumphant return, with the wonderful ‘Ruined’ in amongst new numbers from the band’s then recently released Republic album nobody would have previously heard in a live setting. BBC Transcription Services recordings – produced to service radio stations and usually for a very limited time frame for broadcast – had moved from vinyl to CD but with runs still only in their low hundreds New Order completists would be struggling to own a copy of this one… and I don’t. 04.42 MERIC LONG – A Small Act Of Defiance – Kablooey, LP – Polyvinyl Record Company – 2025 Book-ending a bunch of releases through the years as a member of The Dodos, Kablooey is seemingly Long’s first solo release under his own name since 2006. 07.43 BIOCHEMICAL DREAD – False Kings Of The Earth – 12″ – Pulsolid – 2004 Besides his work with Cabaret Voltaire this 12″ demonstrates there are gaps in my knowledge of Richard H. Kirk’s lengthy discography elsewhere. A copy of ‘False Kings… ‘ however is currently heading my way. RIP, Richard. 13.21 DARKSIDE – One Last Nothing – Download only – Matador – 2025 Including a past member of the 41 Rooms playlist parish, Nicolas Jaar, a US trio currently NOT releasing a 12″, though their Bandcamp visual hints otherwise. 18.32 AGENTS WITH FALSE MEMORIES – Agents With False Memories (extract), CD only – Ash International / Soleilmoon Recordings – 1996 Extract, indeed as Richard H. Kirk promptly returns to show 146 with this four minute snippet from a 53 minute track. 22.34 HUMANIZER – Shinobi – ? – ? – 2000s? Ignoring the slight Liam Gallagher drawl and with zero connection to any Death Metal band of the same name, this might have been Manchester sourced… and maybe with a Peter Hook connection. That’s what I’m vaguely remembering… from over a decade ago. Dunno… A ‘demo’ version, minus vocals, might also get an outing here at some point. 27.08 DIFFERENT GEAR – A Little Bit Paranoid (Extended Mix) * – 12″ – City Rockers – 2002 Courtesy of a ‘Phil Dirtbox’, the vocal is the winner here. 32.59 MERZ – Sorrow In The Sky (Nightingale Vs The Crow) – 7″ b-side – Lotus Records – 2002 The stuff that people sing about… and here with gusto and passion, to boot! 36.55 LUSCIOUS JACKSON – Why Do I Lie? (Sessions at 54th, 11.97) – Stream only – 1997 Vocalist, Jill Cunniff’s tale of lying sounding best live! 40.13 THE POPPY FAMILY – I Was Wondering – 7″ – London – 1971 A bit of a strange arrangement, this one. Albeit with a key change in there – verses with no choruses! Weird and wonderful… and maybe a bit brave in the pop world of the early ’70s, where the only PF track I remember hearing as a young teen was Which Way Are You Going Billy? That won’t be getting a 41 Rooms spin. 42.43 SOPHIE JAMIESON – Camera – I Still Want To Share, LP – Bella Union – 2025 Being over in Brighton recently it seemed appropriate I buy her clear vinyl album from the Bella Union shop and re Camera? It’s the subtle build in Sophie’s vocal and she’ll be here again at some point. 46.59 MARTYN BATES – The Rhyme Of Miracles – Arriving Fire, CD only – Ambivalent Scale – 2014 Martyn instils presence in a tune like few others for me. 50.28 JOSE FELICIANO – First Of May – 7″ b-side – RCA – 1969 ‘Feliciano seems to be on a heavy Bee Gees kick… after ‘Marley Purt Drive,’ he now does ‘First Of May’ and ‘Gotta Get A Message To You.’ And with his highly stylised projection, Jose manages to make them sound totally removed from anything the Gibb brothers originated’. – Disc (edited review of the album, 10 to 23), 15.11.69. As far as I know the Bee Gees tune was only ever released on a 7″ (my ‘format of choice’) for Jose in Mexico, New Zealand, Philippines and Spain and never as an A-side and arranger, Al Capps most probably winced if he ever got to see the NZ pressing below. Strangely, Jose’s very rarely performed the song live. I’ve only noted it three times, including two at London’s Jazz Cafe, in 1996 and again in 1998 and at the former it surfaced nearly under duress. With the audience (maybe unsurprisingly) constantly shouting out for past JF favourites Jose countered, ‘You know there’s a lot of songs you people ask me for that unfortunately… and I’m not being rude, a lot of artists are rude, they do it on purpose, but some of the songs that you ask me to sing, do you know that I haven’t sung them in years and I’ve forgotten the words and rather than make an ass out of myself that’s why I don’t sing them, OK? So, don’t take it personal… I don’t sing those songs anymore. But I’ll tell you what though there’s some that you ask for that I do remember, like this one. I hope that this one will satisfy you.’ That rare sighting was even more surprising considering Jose had taken the rare move of including his own recording of the song when guesting on Brian Matthew’s My Top Twelve for BBC Radio 1 back in June 1974. 54.11 JAPAN – Alien – Quiet Life, LP – Ariola Hansa – 1980 Bedford: Heronscroft, Putnoe, 1980 and Winkles, 1981… with a few Japan gigs thrown in at the time. 58.47 JOHN CALE – Chinese Envoy (M:FANS) – M: FANS, 2 LP – Double Six – 2016 ‘Approached as a reinterpretation of Cale's 1982 improvisational album, Music for a New Society… M:FANS is something of a funhouse mirror reflection of that work, using the basic song-structures of the original album as a starting point and using time, experience and the technological advances of the ensuing years to bring a new focus to the tunes. Some selections are comfortably familiar, while others have a significantly different footprint‘. – KCRW 01.02.32 ICEHOUSE – No Promises (Dance Mix) * – 12″ – Chrysalis – 1990 Fully five years after the track had seemingly done its thing it got an extended outing in Spain. 01.07.58 DAVID BOWIE – This Is Not America (BBC concert) – Bowie At The Beeb, 2CD – EMI – 2000 Part of Bowie’s special set for a small invited audience at the BBC’s Radio Theatre, in London, June 2000. 01.11.29 JOHNNY KEATING – Theme from Z-Cars (Johnny Todd) – 7″ – Piccadilly – 1962 Did I realise the grittier scripts involved here than had been delivered by Jack Warner’s strolling forerunner, Dixon Of Dock Green? Nah, I was five when Z-Cars kicked off but the theme (based on the traditional folk song, Johnny Todd) still brings a fuzzy feel. And Wikipedia will give you the full story on why Everton FC players come out to the tune at home games. 01.13.22 MARC COHN – ‘Walking in Memphis (Mahna Mahna)’ – Stream only – 1990’s? Cohn definitely wouldn’t have seen this coming, as the self proclaiming Mahna Mahna and the Snowths duo upstage him in a short but cheeky mashup (of sorts) I happened on via Youtube a couple of decades ago. I’ll openly admit I was a Muppets fan when they first aired on UK TV back in the mid ’70s and with Statler & Waldorf the stars for me I remember walking my girlfriend of the time, Jill home from work and then running up the hill to my house to record the show. Pre the age of video recorders, at one point there was a stack of ten to twenty AGFA(!!) cassette tapes of the shows in my bedroom. Getting back to Cohn, the fact he’s ‘racing’ a bit here actually adds to the cheeriness and I salute whoever was involved. 01.14.44 BERNARD CRIBBINS – The Hole In The Ground – 7″ – Parlophone – 1962 And like the Z-Cars theme I was five when this was released and I’d have definitely been singing this one in the years close after – and weirdly, although it’s the second tune from ’62 on this show, it’s not the last. 01.16.27 THE BOTS – Fuzzy Math – George W. Bush Greatest Hits, v/artists, CDr only – Spin The World – 2004 I heard this cut and paste work of art somewhere around its ‘release’ and as of 2004… ‘… utilizing the revolutionary Presidential Truth Filter(PTF). The PTF operates like this: All presidential statements are recorded, and made into a huge database. The database is searchable by speech, phrase, keyword, emotional intensity, etc. In parallel, an analysis is made of the historical circumstances of the particular presidency. The question must be asked, what is this man (all men so far…) really all about? What is a defining characteristic of this presidency? The final question which must be addressed by the PTF is, how can we use the assets in the database to concatenate the truth, and make the President speak it? The first attempt was Bushwack, in 1992. This turned into a huge hit before the Presidential election in 1992, though BMI denied that it was ever on the air at all. Through October of that year, stations such as San Francisco’s Live105 were playing it almost hourly. In 1997 Rock The House was a popular download at an early digital music download startup, muzic.com. In 2003 Bushwack2 was released at about the start of the Iraq war. The mood of the song is quite grim, as the truth of those times was interpreted by the PTF. In 2004, the PTF was reprogrammed to emphasize economics and general silliness, and Fuzzy Math was born. We think it’s the best one yet. Judge the results for yourself’. – thebots.net 01.19.26 DREXCIYA – Black Sea – The Journey Home, 12″ EP – Warp – 1995 First heard on either of Colin Faver’s or Colin Dale’s techno shows on KISS FM. Sounds more likely it was the former. 01.24.58 E-DANCER – Heavenly * – 12″ – KMS – 1997 The Inner City (‘Big Fun’) man, Kevin Saunderson with his techno head on. 01.28.51 CHARLES WEBSTER – Your Life * – 12″ – Peacefrog – 2000 Pitched up a bit (‘+3%’ says my file iD) this is a class slice of soulful techno/house. 01.33.11 CHARLOTTE DAY WILSON – Selfish – Download only – Stone Woman Music – 2025 This r&b musician has been around for a decade or so but I wouldn’t have guessed, judging by this slight departure to a ’90s UK garage feel (first half anyway). It suits her. 01.36.48 BENCH – Felice – Bliss, 2LP – Cylinder Recordings – 2000 The fifth appearance on 41 Rooms to date for this pretty much forgotten duo. 01.39.36 BLUE STATES – Your Girl – 12″ EP – Memphis Industries – 1999 First heard on a compilation CD a mate of mine, Sid put together, of fave tracks forwarded by mates of his. Not their own tracks, you understand. 01.43.45 THE MIRACLES – I’ll Try Something New – 7″ – Tamla – 1962 Hellfire! Those breakdown strings mid way are a bit of a jolt! Easy, Smokey! Writer, Robinson’s own version is actually the third to make it to 41 Rooms and his vocal arrangement sounds more like a remake than either Kiki Dee’s ‘straighter’ take or even the Supremes and Temptations stab at the song, when chronologically they both followed this Miracles single. 01.46.14 SMITH & MUDD – Blue River – 2LP – Claremont 56 – 2007 Electronic… downtempo… shuffling… drifting… or maybe flowing. 01.48.38 MERZ – A.M. (Good Morning) * – Single-sided, white label 12″ only – 1995 The second artist to return this show, multi instrumentalist and songwriter, Conrad Merz and his at times very idiosyncratic vocal (‘Many Weathers Apart’, for instance) seem to have trodden their own path through the years. 01.53.45 CRAIG ARMSTRONG (feat ELIZABETH FRASER) – This Love (& The Life That I Have) * – 41 Rooms Soft Mash Up only – Early 2000s I grabbed the extra voice – Virginia McKenna as Second World War spy Violette Szabo, reading the code poem The Life That I Have at the end of the film Carve Her Name With Pride – fully thirty plus years ago and I had a stab at floating it over This Love a long time ago but recently had another go. Aided by Jazz The Glass, we pitched her down slightly and then I took out a chunk of the poem in the second half. Not that it’s going to happen but I reckon it would need the song itself re-arranged/edited to work perfectly but methinks the idea is still a cool one. Show 147 hopefully surfaces Jan 4. Dec x The post Post Punk Plus Podcast Playlist 146 – Original upload 7.12.25 appeared first on 41Rooms.

Art World: Whitehot Magazine with Noah Becker
Artist talk with Pam Poquette, Lawre Stone and Whitehot's Clare Gemima

Art World: Whitehot Magazine with Noah Becker

Play Episode Listen Later Nov 19, 2025 72:26


Artist talk with Pam Poquette, Lawre Stone and Whitehot's Clare Gemima for their 2 person exhibition "Chrysalis" at Tanja Grunert Gallery in Hudson.

What Really Matters: Everyday Spirituality
Ep. 161 Tools for the Chrysalis: What to Do When Everything Falls Apart

What Really Matters: Everyday Spirituality

Play Episode Listen Later Nov 17, 2025 32:42


In this episode I'll share insights from my recent Substack post on the metaphor of the butterfly life cycle and why as a society we are in a "chrysalis phase" right now. This episode includes:The need for grief rituals - both individual and collective - as we navigate this time of dissolutionWhy forgiveness is an essential part of grief workWhy each of us must find our own unique form of creativity to bring to the worldHow to protect what is new and fragileRecognizing other "imaginal cells" in order to collaborateLearn about my books hereCheck out End-of-Life University PodcastRead my latest Substack postMake a donation here

On My Mind with Meghan Telpner
EP 022 - A Midlife Chrysalis: Designing Your Next Chapter From the Heart

On My Mind with Meghan Telpner

Play Episode Listen Later Oct 28, 2025 24:00


What if the discomfort you're feeling isn't a midlife crisis, but a chrysalis—an invitation to become who you were always meant to be? In this episode, airing just after her 46th birthday, Meghan Telpner explores how midlife isn't about decline, but about designing your next chapter from the heart rather than from obligation or fear. Learn why your body's whispers are getting louder, how to distinguish between what's truly yours and what you've been performing, and why the chrysalis stage requires dissolving old versions of yourself to make room for what wants to emerge. If you're ready to stop living from the outside in and start designing from your deepest knowing, this episode offers both permission and a path forward. Essential listening for anyone in their 40s and 50s who's ready to pivot from who they think they should be to who they actually are. Links + Resources Full show notes Shop: 30% off Rise + Shine: Guided Path to Heart-Led Living and Leadership

Do Good To Lead Well with Craig Dowden
Redefining Midlife with Power and Purpose: An Important Conversation with Bestselling Author Chip Conley

Do Good To Lead Well with Craig Dowden

Play Episode Listen Later Oct 23, 2025 52:40


What if midlife could be the most transformative period of your life? Join us in a compelling conversation with Chip Conley, renowned entrepreneur and bestselling author, who shares his transformative insights on embracing the midlife journey. Drawing from his pivotal experiences at Airbnb and his groundbreaking work with the Modern Elder Academy (MEA), we explore how Chip's latest book, "Learning to Love Midlife," challenges ageist stereotypes and redefines midlife as a time for renewal and growth.Redefining what it means to be a "modern elder," Chip shares his unique perspective on combining wisdom with curiosity. By reframing midlife as a "midlife chrysalis" rather than a crisis, he opens up new avenues for personal transformation and fulfillment. Drawing on insights from thought leaders like Becca Levy and Arthur Brooks, Chip and I discuss how emotional intelligence, social relationships, and spirituality are key areas for growth during this pivotal life stage.Finally, we journey through the concepts of generativity and life purpose as they evolve across life's stages. Drawing from spiritual and philosophical insights, we discuss how older generations can impart wisdom while embracing new purposes, and how younger generations can navigate the complexities of an AI-driven world. We delve into the importance of understanding one's life story and finding one's "ikigai," a harmonious blend of passion, proficiency, reward, and necessity. Let this conversation inspire you to see midlife not as a time of crisis but as a powerful opportunity for growth and discovery at any age.What You'll Learn- Why midlife is not a crisis; it's an opportunity.- How to embrace aging as an opportunity for personal growth- Harnessing the value of wisdom gained through life experiences- The importance of fostering meaningful friendships in midlife- Strategies for redefining one's purpose during midlife transitionsTake the Midlife Pathfinder Quiz: https://reportcard.meawisdom.com/pathfinder-quizPodcast Timestamps(00:00) – Learning to Love Midlife(13:09) – Midlife as a Chrysalis, Not Crisis(18:39) – What is a Modern Elder? Harnessing Our Wisdom and Life Experience(35:26) – The Power of Friendships(43:48) – Generativity and Purpose Across Different Stages of Life: Finding Your "Ikigai"KEYWORDSChip Conley, Positive Leadership, The Art of Meaningful Conversation, Curiosity, Learning to Love Midlife, Modern Elder, Challenging Ageist Stereotypes, Cultivating Wisdom, Embracing Transformation, Continuous Growth, Positive Mindset, Social Wellness, The Power of Friendship, Living with Purpose, Generativity, Creating our Life Story, Ikigai, Hero's Journey, Emotional Intelligence, Social Relationships, Spirituality, Longevity, Adaptability, Lifelong Learning, CEO Success

Honest HR: A Podcast from SHRM Spilling HR Truths
Using Stay Interviews to Spot Red Flags and Boost Retention

Honest HR: A Podcast from SHRM Spilling HR Truths

Play Episode Listen Later Sep 30, 2025 31:57


Stay interviews go beyond job satisfaction surveys — they uncover why employees stick around, what frustrates them, and what might send them looking elsewhere. Carlyne Ervin, SHRM-CP and VP of HR at Chrysalis, a nonprofit removing barriers to work, joins host Monique Akanbi, SHRM-CP, to share how HR can make these proactive conversations meaningful to minimize the high expense of turnover. She also explains how to spot hidden red flags and turn insights into actions that keep your top talent engaged and committed before it's too late — and you're saying goodbye at the exit interview.  This podcast is approved for .5 PDCs toward SHRM-CP and SHRM-SCP recertification. Listen to the complete episode to get your activity ID at the end. ID expires October 1, 2026.  Subscribe to Honest HR to get the latest episodes, expert insights, and additional resources delivered straight to your inbox: https://shrm.co/voegyz   ---  Explore SHRM's all-new flagships. Content curated by experts. Created for you weekly. Each content journey features engaging podcasts, video, articles, and groundbreaking newsletters tailored to meet your unique needs in your organization and career. Learn More: https://shrm.co/coy63r

Evoke Greatness Podcast
Rewilding Your Life and Leadership with Aubrey Morgan Yee

Evoke Greatness Podcast

Play Episode Listen Later Sep 23, 2025 27:24 Transcription Available


Recording & Mixing
Vocal Processing Techniques

Recording & Mixing

Play Episode Listen Later Sep 16, 2025 34:12


Eddie Bazil explores advanced vocal processing techniques to achieve a clean, professional vocal track. He demonstrates how to control sibilance, tame resonances and apply quick corrective steps that enhance vocal clarity and ensure the performance sits perfectly in the track.Chapters00:00 - Introduction00:30 - Common Vocal Track Issues01:04 - Example 1: De-essing Sibilance08:57 - Example 2: Taming Resonance With EQ16:13 - Example 3: Reverb Ducking25:22 - Example 4: Frequency DuckingTrack CreditsExample 1 - written and performed by David Plummer and Becky Bremner - https://www.smokinggoats.co.ukExamples 2, 3 and 4 - ‘Puppet' written, performed and recorded by John Walden, vocals by Yvonne McKeown#SSLVocalStrip #FabFilterProDS #FabFilterProQ3 #FabFilterMBC #FabFilterProC #UnfilteredAudioTails #TokyoDawnNovaGEEddie Bazil BiogEddie Bazil launched his music industry career at the age of 17 as a synth programmer for a range of Electro / New Wave bands, including Art Of Noise, Spandau Ballet, Pet Shop Boys, Bobin, Paul Dee, DJ Krush, DJ Shadow, Jets Orchestra, and many more. By his 20s, he was working as a sound designer for Akai, Roland, Emu/Ensoniq, eventually signing on exclusively with the latter. Later, due to a growing demand for software instruments and libraries, Eddie began developing libraries for various software manufacturers, including Native Instruments, Kiesel, Sound Effects Library, Rob Papen, Arturia, and Propellerheads.During this time, he trained in music production. He soon gained several prominent contracts working with some notable artistes such as Busta Rhymes, Greensleeves, 9 Bar, SFP, Sleeveless, Chris Campbell and Gam Productions. He contracted to Island Records and Chrysalis as a producer and remixer, and was commissioned to write the score for Macbeth that ran at 2 Way Mirror at Alexander Palace for the Cambridge Shakespeare Company. This led to him offering educational workshops and classes, and becoming a contributing creator and Forum moderator for Sound On Sound.Recently, he was invited by the Recording Academy to become a professional member, approved educator, and mentor for their member base. Eddie now concentrates on providing private sound design and mixing/production tuition, and creating content for Sound On Sound magazine.https://eddiebazil.co.uk/Catch more shows on our other podcast channels: https://www.soundonsound.com/sos-podcasts

Crosscurrents
Sights + Sounds: B. DeVeaux's debut album 'Chrysalis'

Crosscurrents

Play Episode Listen Later Aug 21, 2025 8:18


Oakland singer and songwriter. B. DeVeaux is a self-described “creative force.” She has performed with major artists such as Daveed Diggs, Patrice Rushen, and Kehlani. And she just dropped her debut, neo-soul album “Chrysalis.” The host of KALW's Sights and Sounds, Jenee Darden. She recently spoke to B. DeVeaux and asked how she began her journey to become a musician.

Crosscurrents
SHOW: Sprouting Inspiration

Crosscurrents

Play Episode Listen Later Aug 21, 2025 26:50


Today, one museum internship emphasizes diversity in science. We'll visit the Cal Academy "Careers in Science" program. Then, Oakland singer B. DeVeaux talks about their debut neo-soul album, "Chrysalis." And, how art brought a slice of brightness to the incarcerated men at San Quentin.

Soul of Travel
Choosing the Midlife Chrysalis with Christine Sperber

Soul of Travel

Play Episode Listen Later Aug 13, 2025 69:05


Send us a textIn this episode of Soul of Travel, Season 6: Women's Wisdom + Mindful Travel, presented by @journeywoman_original, Christine hosts a soulful conversation with Christine Sperber.Christine Sperber, Co-Founder and Chief Experience Officer at MEA, is chief architect of the embodied, experiential aspects of its workshops and programs. She is a former World Cup snowboarder and serial entrepreneur who has launched and grown successful hotels, businesses, and industry-evolving ideas in the sports and hospitality worlds and beyond. The word her workshop participants use most often to describe her is “badass” in recognition of her irrepressible energy and ability to make things happen.As MEA co-founders, Christine and Chip worked together to turn the idea of a Modern Elder Academy into a reality. She is a devoted team builder whose authenticity, values-based leadership skills, and empathetic engagement create community wherever she focuses her attention. She is a passionate activist and steward of the land and is dedicated to creating transformative experiences that change people's lives. She makes everything she gets involved in more fun, more meaningful, and more human.Christine Winebrenner Irick and Christine Sperber discuss:· Transforming the idea of a “midlife crisis” into a Midlife Chrysalis· Creating community for important conversations and meaningful connections· Seeking wisdom and knowledge during life transitions and the need for more support, including during menopause, empty-nesting, retirement and more· MEA's upcoming Women's Health: Reclaim Your Agency, Power, and Freedom retreat· Joy as ResistanceJoin Christine now for this soulful conversation with Christine Sperber.

Sternengeschichten
Sternengeschichten Folge 663: Die Zerstörung von Chrysalis und die Ringe des Saturn

Sternengeschichten

Play Episode Listen Later Aug 8, 2025 16:09


STERNENGESCHICHTEN LIVE TOUR 2025! Nächste Shows in LEVERKUSEN (28.9). Tickets unter https://sternengeschichten.live Vor 100 Millionen Jahren ist etwas passiert, das Saturn zu seinen faszinierenden Ringen verholfen hat. Daran beteiligt waren der Planet Neptun, ein Mond den es nicht mehr gibt und jede Menge Dynamik. Mehr erfahrt ihr in der neuen Folge der Sternengeschichten: Wer den Podcast finanziell unterstützen möchte, kann das hier tun: Mit PayPal (https://www.paypal.me/florianfreistetter), Patreon (https://www.patreon.com/sternengeschichten) oder Steady (https://steadyhq.com/sternengeschichten) Sternengeschichten-Hörbuch: https://www.penguin.de/buecher/florian-freistetter-sternengeschichten/hoerbuch-mp3-cd/9783844553062

Happy and Healthy with Amy Lang
Letting Go and Looking Forward: Your Second Spring

Happy and Healthy with Amy Lang

Play Episode Listen Later Aug 6, 2025 27:13


You've been told menopause means decline—but what if it's actually a time for metamorphosis? What if it's your Second Spring—a powerful time to release outdated beliefs, embrace new possibilities, and take charge of your brain health. In the season 1 finale, we're talking about letting go of the beliefs, roles, and expectations that are holding you back so you can step boldly into this next chapter of life. What to Listen For[00:01:50] The pivot from weight loss to brain health and Alzheimer's prevention—and why it matters now more than ever.[00:04:50] The surprising link between menopause, brain changes, and dementia risk.[00:06:30] How “second spring” thinking transforms how you see menopause.[00:07:20] The butterfly chrysalis analogy: why breakdown is preparation for flight.[00:08:10] Limiting beliefs to release—like “I'm too old to start something new” or “my best years are behind me.”[00:10:20] How perfectionism and people-pleasing silently harm your brain.[00:11:30] Why letting go of roles, clutter, and outdated dreams frees up brain energy.[00:13:10] Menopause symptoms reframed as signs of transformation, not decline.[00:18:20] How sleep, insulin resistance, and hot flashes all connect to Alzheimer's risk.[00:21:10] Details about the free quiz: “Is this just brain fog or early signs of Alzheimer's?”Conclusion Menopause isn't the end—it's your beginning. This second spring is your chance to protect your brain, reclaim your energy, and create the life you want. Listen to this episode for the inspiration, science, and strategies to step into your most powerful chapter yet.Resources MentionedTake The Quiz: Is It Just Brain Fog or Early Signs of Alzheimer'sYouTube Channel: Happy & Health with AmySubscribe & Review in iTunesIf you like what you hear, please subscribe to my podcast.  I encourage you to do that today as I don't want you to miss an episode.  Click here to subscribe on iTunes!Now if you're feeling extra loving, I would be really grateful if you left me a review over on iTunes, too. Those reviews help other people find my podcast and they're also fun for me to go in and read. Just click here to review, select “Ratings and Reviews” and “Write a Review” and let me know what your favorite part of the podcast is.Thank you!RESOURCES: Register for the FREE Masterclass: 5 Keys to Protecting Your Brain Health Book a FREE Discovery Call with Amy Lang Order Amy's book Thoughts Are Habits Too: Master Your Triggers, Free Yourself From Diet Culture, and Rediscover Joyful Eating. Follow Amy on Instagram @habitwhisperer

The Pain Game Podcast
Unsilencing the Survivors of the Troubled Teen Industry

The Pain Game Podcast

Play Episode Listen Later Jul 22, 2025 51:38


⚠️ Content Warning: This episode contains discussion of institutional abuse, medical neglect, and trauma experienced by survivors of the troubled teen industry. Please listen with care.This one's heavy—but necessary. In this gripping episode, Lyndsay Soprano sits down with Meg Appelgate to expose the disturbing realities of the troubled teen industry—a multi-billion-dollar machine built on silence, shame, and survival.Meg shares her personal story of being institutionalized as a teenager, detailing the abuse, medical neglect, and psychological control she endured under the guise of “treatment.” From attack therapy to forced circle sessions, this conversation pulls back the curtain on an industry that claims to help struggling youth but often leaves them with deeper wounds.Lyndsay and Meg dig into the lack of evidence-based practices, the systemic failures that keep these places running, and the long-term physical and emotional toll they take on survivors. They talk about how trauma isn't just something you move past—it lives in the body, demands attention, and deserves to be addressed with care, not cruelty.But this isn't just about exposing what's broken. It's about amplifying the voices of survivors and advocating for real change. Meg shares how her organization, Unsilenced, is helping others reclaim their stories, seek justice, and hold the industry accountable.Tune in if you're ready to hear the truth behind the troubled teen industry—and why it's time to stop sending pain away to be fixed behind closed doors.Find Meg Appelgate Online Here:Instagram: @megappelgateFacebook: Meg AppelgateLinkedIn: Meg AppelgateWebsite: megappelgate.comTikTok: @megappelgateBook: Becoming UnsilencedFind The Pain Game Podcast Online Here:Website: thepaingamepodcast.comInstagram: @thepaingamepodcastFacebook: The Pain Game PodcastLinkedIn: Lyndsay SopranoYouTube: The Pain Game PodcastHighlights:(00:00) Introduction to Chronic Pain and Trauma(01:04) Personal Trauma and Its Impact(03:45) The Troubled Teen Industry: An Overview(05:34) Meg's Abduction and Institutionalization(09:12) The Dark Side of the Troubled Teen Industry(11:33) The Long-Term Effects of Institutional Abuse(13:46) Experiences Within the Institutions(18:44) The Cult-like Environment of Chrysalis(23:09) The Psychological Manipulation and Control(28:32) Medical Neglect and Its Consequences(34:15) Life After Institutionalization(37:47) Healing and Advocacy(45:46) Conclusion and Call to Action

Something Was Wrong
S24 Ep2: Unsilenced

Something Was Wrong

Play Episode Listen Later Jul 18, 2025 52:19


*Content warning: institutional child abuse, childhood abuse, death of a child, suicide, psychological, physical and sexual violence, abduction, kidnapping, disordered eating, stressful themes, disability abuse, ableism, PTSD, medical abuse and neglect.  *Meg Appelgate's Work: Meg Appelgate's website here: https://megappelgate.com/my-story/  Meg Appelgate's nonprofit, Unsilenced here: https://www.unsilenced.org/  Meg Appelgate's memoir, Becoming UNSILENCED: Surviving and Fighting the Troubled Teen Industry: https://megappelgate.com/book/  *Free + Confidential Resources + Safety Tips:  somethingwaswrong.com/resources    Please note: Kenny Pannell and Mary Alexine have never publicly responded to allegations against them. They appear to be no longer involved with Chrysalis in Eureka, Montana since its sale to Embark Behavioral Health. Chrysalis opened in 1998; however, the exact year when Kenny and Mary left is not readily available information. *Correction: In a previous draft of this episode, we incorrectly reported that, "Intermountain Hospital in Boise, Idaho, which is still in operation and under the ownership of Intermountain Health." which is incorrect. Intermountain Health has no affiliation with Intermountain Hospital. We apologize for the error and appreciate it being brought to our attention. Thank you!  *Sources  Adverse events in children: predictors of adult physical and mental conditions, Pub Med https://pubmed.ncbi.nlm.nih.gov/25225793/  Breaking Code Silence https://www.breakingcodesilence.org/  Chrysalis, InnerChange https://innerchange.com/programs/chrysalis/  Chrysalis School, Unsilenced https://archive.unsilenced.org/program-archive/us-programs/montana/chrysalis-school/  Consonance Capital Partners Acquires Majority Stake in Youth-Focused Embark Behavioral Health, Behavioral Health Business  https://bhbusiness.com/2023/02/09/consonance-capital-partners-acquires  Highland Park teen's death leads parents to call for change in troubled teen industry, NBC 5 Chicago https://www.nbcchicago.com/investigations/highland-park-teen  The Impact of Adverse Childhood Experiences on Health and Development in Young Children.  https://pmc.ncbi.nlm.nih.gov/articles/PMC8882933 Intermountain Hospital, Unsilenced https://archive.unsilenced.org/program-archive/us-programs/idaho/intermountain-hospital/  Meg's Testimony – Chrysalis School and Intermountain Hospital, Unsilenced https://archive.unsilenced.org/megs-story/  Parents say Discovery Ranch Academy's negligence led to their son's death in new lawsuit, The Salt Lake Tribune https://www.sltrib.com/news/health/2025/05/17/parents-sue-utahs-discovery-ranch/  Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study, Pub Med https://pubmed.ncbi.nlm.nih.gov/9635069/  Residential Consonance Capital Partners Acquires Majority Stake in Youth-Focused Embark Behavioral Health, Behavioral Health Business https://bhbusiness.com/2023/02/09/consonance-capital-partners-acquires  Taylor Goodridge TikTok, Meg Appelgate https://www.tiktok.com/@megappelgate/video/  A therapeutic boarding school for adolescent and teen girls in Montana, Embark Behavioral Health https://www.embarkbh.com/locations/montana/chrysalis-residential-treatment-center/  *SWW S23 Theme Song & Artwork:  Glad Rags: https://www.gladragsmusic.com/  The S24 cover art is by the Amazing Sara Stewart Follow Something Was Wrong: Website: somethingwaswrong.com  IG: instagram.com/somethingwaswrongpodcast TikTok: tiktok.com/@somethingwaswrongpodcast  Follow Tiffany Reese: Website: tiffanyreese.me  IG: instagram.com/lookieboo

Play It Brave Podcast
The Midlife Chrysalis: Transforming Crisis into a Calling with Dr. Devaa Haley Mitchell

Play It Brave Podcast

Play Episode Listen Later May 29, 2025 56:41


What if midlife wasn't a crisis—but a chrysalis? In this powerful and heartfelt conversation, D'Arcy sits down with spiritual leader and transformational guide Dr. Devaa Haley Mitchell to reframe the way we view this pivotal life stage. Together, they unpack the idea of midlife as a sacred period of unraveling, reclaiming, and radiating—a time of deep transformation that prepares us to emerge more fully expressed, sovereign, and whole. From the rise of the Queen archetype to the cultural stories we've inherited about aging, this episode explores how truth-telling, community, and feminine leadership can help us navigate the unknown with courage and grace. If you're feeling the stirrings of change or longing to embrace your next chapter with intention, this one's for you.   Key Takeaways: Midlife is not a breakdown—it's a metamorphosis. The Queen archetype offers a fresh and empowering lens on aging and leadership. Cultural narratives about aging shape how we see ourselves—and we can rewrite them. Truth-telling is a liberating force for healing and connection. Feminine leadership is intuitive, inclusive, and deeply needed in today's world. The chrysalis journey unfolds in stages: unraveling, reclaiming, and radiating. Community support is essential during times of transition. Embracing sensuality and creativity is key to holistic well-being. Awareness of societal conditioning can help us reclaim our power and purpose. The unknown isn't something to fear—it's an invitation to grow. Whether you're in your thirties, forties, fifties, or beyond, this conversation is a gentle reminder: the unraveling is part of the becoming. And you're not alone.   Meet Devaa: For Dr. Devaa Haley Mitchell, transformation isn't just a concept—it's a way of life. She's dedicated to helping people reconnect with their deepest selves, unlock their leadership gifts, and step into their full potential. As the Co-Founder of The Shift Network, a multiple 7-figure educational platform, Devaa has helped bring life-changing programs to over 3.2 million students worldwide. She's also built an online summit that served 130,000 women across 160 countries—all while growing her company from the ground up. Through her private practice, Devaa supports her clients with Soul and Strategy Coaching to work on both the “inner” work of feminine leadership as well as the “outer” work of visionary strategy and implementation. She also leads women through a comprehensive Midlife Chrysalis process to gracefully navigate the many changes that happen in midlife. Finally, Devaa offers psychedelic integration as well as microdose coaching to enhance creativity and focus, while mitigating the impacts of anxiety and depression. Devaa earned both her BA and MA from Stanford University. She received her Doctorate in Ministry from Wisdom University (now known as Ubiquity University) and is also an ordained interfaith minister. She was awarded a Fulbright Scholarship for her ecological anthropology work with indigenous groups in the Brazilian Amazon. Devaa also completed her Psilocybin Guides certification through Bodhi Academy in Oregon. Earlier in her career, Devaa was a Management Consultant at the Boston Consulting Group where she consulted with Fortune 500 Companies. She later worked as the founding Executive Director of the Full Circle Fund, a thriving venture philanthropy group, followed by a senior Director role at the Institute of Noetic Sciences. She is also a member of the prestigious Evolutionary Leaders group. In her spare time, Devaa is a musician, and her songs fuse East and West with danceable grooves. Her most recent album, Rebirth, reached #1 on Amazon in the New Age Category.   Connect with Devaa: Devaa's course – Awaken Your Archetypal Feminine Codes: A Guided Initiation Into Your Sacred Power and Leadership – will go live on June 6, 2025. Visit Devaa's Website to learn more about her offerings and sign up for her Dynamic Manifestation Video Series, or follow along on Instagram.

Tales To Terrify
Tales to Terrify 693 Matt Hollingsworth

Tales To Terrify

Play Episode Listen Later May 9, 2025 52:53


Welcome to episode 693. We have one tale for you this week, about a jaded man burdened with a terrible responsibility who seeks solace in a new friend.COMING UPGood Evening: 00:01:06[Trigger] Matt Hollingsworth's The Sin Eater's Chrysalis as read by Rish Outfield: 00:03:16TRIGGER WARNINGSThe Sin Eater's Chrysalis contains scenes of Animal Death.PERTINENT LINKSSupport us on Patreon! Spread the darkness.Shop Tales to Terrify MerchMatt HollingsworthOriginal Score by Nebulus EntertainmentNebulus on FacebookNebulus on InstagramSPECIAL THANKS TOAmanda CarrilloLestle BaxterOrion D. HegreSupport this show http://supporter.acast.com/talestoterrify. Hosted on Acast. See acast.com/privacy for more information.

Sound Opinions
Reviews of Lucy Dacus, Saba & No I.D., Mekons, etc. Plus RIP Clem Burke & Dave Allen

Sound Opinions

Play Episode Listen Later Apr 18, 2025 50:23


As spring is springing, the volume of new albums coming out is hard to keep up with. This week hosts Jim DeRogatis and Greg Kot dig out from “music mountain” by reviewing new albums from Lucy Dacus, Saba and No ID, Mekons and Perfume Genius. They also pay tribute to Clem Burke of Blondie and Dave Allen of Gang of Four.Join our Facebook Group: https://bit.ly/3sivr9TBecome a member on Patreon: https://bit.ly/3slWZvcSign up for our newsletter: https://bit.ly/3eEvRnGMake a donation via PayPal: https://bit.ly/3dmt9lUSend us a Voice Memo: Desktop: bit.ly/2RyD5Ah Mobile: sayhi.chat/soundops Featured Songs:Lucy Dacus, "Ankles," Forever is a Feeling, Geffen, 2025The Beatles, "With A Little Help From My Friends," Sgt. Pepper's Lonely Hearts Club Band, Parlophone, 1967Blondie, "Heart Of Glass," Parallel Lines, Chrysalis, 1979Blondie, "Atomic," Eat to the Beat, Chrysalis, 1980Blondie, "Call Me," American Gigolo, Chrysalis, 1980Gang of Four, "Ether," Entertainment!, EMI, 1979Gang of Four, "Damaged Goods," Entertainment!, EMI, 1979Lucy Dacus, "For Keeps," Forever is a Feeling, Geffen, 2025Lucy Dacus, "Most Wanted Man," Forever is a Feeling, Geffen, 2025Lucy Dacus, "Lost Time," Forever is a Feeling, Geffen, 2025Saba and No I.D., "head.rap (ft. Madison McFerrin, Ogi & Jordan Ward)," From the Private Collection of Saba and No I.D., From the Private Collection of Saba and No I.D., 2025Saba and No I.D., "Every Painting Has a Price (feat. Eryn Allen Kane & BJ Chicago Kid)," From the Private Collection of Saba and No I.D., From the Private Collection of Saba and No I.D., 2025Saba and No I.D., "Breakdown," From the Private Collection of Saba and No I.D., From the Private Collection of Saba and No I.D., 2025Saba and No I.D., "How to Impress God," From the Private Collection of Saba and No I.D., From the Private Collection of Saba and No I.D., 2025Perfume Genius, "Clean Heart," Glory, Matador, 2025Perfume Genius, "No Front Teeth (feat. Aldous Harding)," Glory, Matador, 2025Perfume Genius, "Left For Tomorrow," Glory, Matador, 2025Perfume Genius, "Full On," Glory, Matador, 2025Mekons, "Mudcrawlers," Horror, Fire, 2025Mekons, "You're Not Singing Anymore," Horror, Fire, 2025Mekons, "Private Defense Contractor," Horror, Fire, 2025Mekons, "The Western Design," Horror, Fire, 2025Mekons, "War Economy," Horror, Fire, 2025Mekons, "Sad and Sad and Sad," Horror, Fire, 2025Rosanne Cash, "Seven Year Ache," Seven Year Ache, Columbia, 1981See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Sound Opinions
Women in Ska & Opinions on Throwing Muses

Sound Opinions

Play Episode Listen Later Mar 28, 2025 50:39


Hosts Jim DeRogatis and Greg Kot talk with author Heather Augustyn about her book "Rude Girls: Women in Two Tone Ska and One Step Beyond." The hosts also review the new album by Throwing Muses.Join our Facebook Group: https://bit.ly/3sivr9TBecome a member on Patreon: https://bit.ly/3slWZvcSign up for our newsletter: https://bit.ly/3eEvRnGMake a donation via PayPal: https://bit.ly/3dmt9lUSend us a Voice Memo: Desktop: bit.ly/2RyD5Ah Mobile: sayhi.chat/soundops Featured Songs:The Bodysnatchers, "Ruder Than You," Ruder Than You (Single), 2 Tone, 1980The Beatles, "With A Little Help From My Friends," Sgt. Pepper's Lonely Hearts Club Band, Parlophone, 1967Throwing Muses, "Summer of Love," Moonlight Concessions, Fire, 2025Throwing Muses, "South Coast," Moonlight Concessions, Fire, 2025Throwing Muses, "Theremini," Moonlight Concessions, Fire, 2025Throwing Muses, "Sally's Beauty," Moonlight Concessions, Fire, 2025Rhoda with the Special A.K.A., "The Boiler," The Boiler (Single), 2 Tone, 1981The Selecter, "On My Radio," On My Radio (Single), 2 Tone, 1979The Bodysnatchers, "Easy Life," Easy Life (Single), 2 Tone, 1980The Fun Boy Three with Bananarama, "It Ain't What You Do It's the Way That You Do It," Fun Boy Three, Chrysalis, 1982The Fun Boy Three, "Our Lips Are Sealed," Waiting, Chrysalis, 1983The Deltones, "Oddball Boy," Nana Choc Choc In Paris, Unicorn, 1989The Lemons, "English Summer," English Summer (Single), Race, 1981Tom Petty and the Heartbreakers, "I Won't Back Down," Full Moon Fever, MCA, 1989See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome to Night Vale
259 - Chrysalis

Welcome to Night Vale

Play Episode Listen Later Dec 1, 2024 24:34


After many centuries, the chrysalis is stirring.Weather: “Adrift“ by tinfoldOriginal episode art by Jessica HayworthRead episode transcriptsUNLICENSED Season 2 is here! Only on AudiblePre-order the Welcome to Night Vale Roleplaying Game today!Sign up for the Night Vale newsletter for good news and recommendations.Patreon is how we exist! If you can, please help us keep making this show.Music: DisparitionLogo: Rob WilsonWritten by Joseph Fink, Jeffrey Cranor & Brie WilliamsNarrated by Cecil BaldwinFollow us on Twitter, Facebook, and Instagram.Check out our books, live shows, store, membership program, and official recap show at welcometonightvale.comA production of Night Vale Presents.