Podcasts about Manchester

W/ BALANCE AND COMPOSURE AND SOUL BLIND16/01 LONDON, UK @ O2 FORUM KENTISH TOWN17/01 MANCHESTER, UK @ O2 RITZ18/01 GLASGOW, UK @ SWG3 GALVANIZERS20/01 BRISTOL, UK @ O2 ACADEMY 22/01 DUBLIN, IE @ ACADEMYw/ Angel Du$tApr 25, 2026 Sick New World - Las VegasApr 30, 2026 The Triffid Brisbane, AustraliaMay 2, 2026 170 Russell Melbourne, AustraliaMay 3, 2026 Liberty Hall Sydney, AustraliaMay 5, 2026 Lion Arts Factory Adelaide, AustraliaMay 6, 2026 Amplifier Bar Perth, AustraliaJul 9, 2026 Two Thousand Trees Festival Cheltenham, EnglandOct 24, 2026Sick New World Texas Dallas, TX

**Re-Release** Season 4 Episode 13: Is Sarah Hunter's Murder Solved? We are re-releasing this episode as we have an update to her case being published tomorrow. Sarah Hunter was last seen in Manchester, Vermont on September 19, 1986. Amanda, Drew, and Jane, the lone survivor of the Connecticut River Valley Serial killer, talk about the circumstances around her murder, the botched investigation, and where the case sits today. We listen to Dr. John Philpin's profile he gave in the 1980's and discuss this along side what little is known about the main suspect David Morrison.  Follow or Visit Invisible Tears everywhere at: ⁠https://linktr.ee/invisibletearspodcast⁠   Music Credits dreamy-piano-soft-sound-ambient-background-4049 Music by ⁠WinkingFoxMusic⁠ from ⁠Pixabay⁠ Resources for this episode: ⁠https://www.youtube.com/watch?v=jvp8RZnhuBQ⁠ ⁠https://www.timesunion.com/sports/article/All-In-Murdered-golf-pro-Sarah-Hunter-s-case-17190793.php⁠ ⁠https://suncommunitynews.com/news/2850/detectives-solve-1986-vermont-murder-mystery/⁠ ⁠https://www.cbsnews.com/news/charges-in-1986-golf-pros-slaying-dropped-over-evidence-error/ Learn more about your ad choices. Visit megaphone.fm/adchoices

It's the calm between the Christmas storms in the Cassidy-Humphreys household and Nat, Marc, and Eliza have popped into the pod room to debrief Christmas so far, and brief on the rest to come. Enjoy! xx Please subscribe, follow, and leave a review. xxx You can find us in all places here; ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podfollow.com/lifewithnat/view⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ We're on Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/lifewithnatpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Nat's insta: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@natcass1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Marc's insta: @camera_marc Neice's insta: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@natsnieces⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Tony's insta: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@tonycass68⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Linny's insta: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@auntielinny.lwn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ MORE LIVE SHOW! 07/02/2026 Brighton, The Forge TICKETS 08/02/2026 Newcastle upon Tyne, The Stand TICKETS 25/02/2026 Folkestone, Quarterhouse TICKETS 28/02/2026 Colchester, Arts Centre TICKETS 07/03/2026 Manchester, Fairfield Social Club TICKETS 22/03/2026 Leeds, The Wardrobe TICKETS 29/03/2026 Bristol, The Gaffe - TICKETS Book Club: November's book - All Together for Christmas by Sarah Morgan & December's book (optional extra for the speedy readers) - A Heart for Christmas: Advent Romance by Sophie Jomain Nat's solo chats - any rants always welcome!  Scraping the Barrel - SCAN AND SHOP VIRGIN NO LONGER! Bonce vs list! - Are you a list maker? Always collecting for Nostalgia Fest! What's brewing with the Nieces - are we all skipping the end of summer, all of autumn and going straight to Christmas - Nat's door is! Group chat ettiquette & pranks. Nice Lorraines… get in touch! Advent calendars & gift recommendations v. welcome! Things we're nagging with Linny about - More lateness stories and some cleaning questions, please! The Tony talks chatter - Keep your DIY questions coming, also open to some saucy two paragraph stories for Tony to read out at the Southend show - think cheeky postcards (both in tone and length)! Can we make Tony an influencer and get him any freebies?  TBC Cultural differences ep - inspired by Linny's Mediterranean heritage and her & Ellia's Italian trip, we'd love to hear about the cultural differences you've noticed between the UK and basically ANYWHERE else!  A 'Keep It Light Media' Production Sales, advertising, and general enquiries: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@keepitlightmedia.com⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

#254Our WhatsApp  groupProperty Engine discounts (Code: EXPAT)Starter: 30 day trialPro: 30 day trial/3 mths 1/2 price, Ultimate: 1/2 price 3 monthsGoalsettingLeave a review37 Question Due Diligence Checklist / Auction GuideOur Sponsors: Finnigan McNeill Property GroupThis is the fifth episode in this year's mini-season celebrating the 12 Days of Christmas.We're releasing daily bite sized episodes.Each one contains clips from three of my favourite episodes from 2025.Today's show features extracts from:#224: Why You Should Invest in Northern Ireland Property (Eimear Gourley)#225: Structural Secrets for UK Property Investors (Paul Fowler)#223: The Ticking Time Bomb of EPCs in UK Property (Solo)KeywordsUK property podcast, Expat property podcast, UK buy to let podcast, Property investment UK podcast, UK property investment tips, Investing in Northern Ireland property, Expat property story, UK rental property advice, Energy Performance Certificate advice UK (EPC), EPC changes 2026 UK landlords, UK property market podcast, Structural issues property UK, UK property portfolio management, Hands free property investing UK, Property renovation UK podcast, How to identify structural issues in UK properties, Landlord tips for EPC changes 2026, Buying to let in Belfast Northern Ireland podcast, UK property legislation for expats, Maximising capital growth Northern Ireland property, Avoiding subsidence problems in UK rentals, Retrofit contractors advice UK property podcast, Grants for energy improvements UK landlords, UK stamp duty for expats, Rental yield Belfast, UK property legislation differences, Property sourcing companies UK review, Podcast for investing in Manchester property

As we near the end of 2025, it's time to take stock of the year. What were the big events this year and how might they impact the field of comparative education? What new ideas emerged? And where is our field headed in 2026? Continuing this FreshEd tradition, Susan Robertson and Mario Novelli join me for the last episode of the year. Mario Novelli is professor in the political economy of education at the University of Sussex. Susan Robertson is a professor of education at Wolfson College at the University of Cambridge as well as at the University of Manchester. They co-edit the journal Globalisation, Societies and Education. freshedpodcast.com/2025inreview -- Get in touch! Twitter: @FreshEdpodcast Facebook: FreshEd Email: info@freshedpodcast.com

Robb Kelly, PhD – The Recovery Expert – was born in Manchester, England. He grew up in a family of musicians and developed a deep love for music at an early age. He was performing on stage by the age of nine. During his early twenties, he worked at the prestigious Abbey Road Studios as a session musician in London.Addiction was always close to his heart, as Dr. Kelly was born into a family with a history of alcoholism. He began drinking and using drugs at a young age, but he managed to stay on a path of success, moving to Oxford in the early 1980s to pursue a PhD in Psychology at the esteemed University of Oxford. He continued to drink heavily during his time in Oxford—yet still managed to complete his doctoral studies, earning a PhD in psychology in 1984.Even though he was a heavy drinker, no one would have predicted that he would end up living on the streets of Manchester, homeless and alone. He recalls a night when he had a staggering realization about his own alcoholism. It would later inspire two of his most popular catchphrases: “The Problem is not our Drinking, it is our Thinking” and “Step out of the Disease, and into the Solution.”Dr. Kelly was standing on a street corner one night in Manchester, body trembling from alcohol withdrawal. He stood in front of a liquor store, shaking and desperately waiting for it to open. He knew that as soon as he took that first sip of alcohol, he would feel relief.As soon as the store opened, he rushed inside. The clerk grabbed a bottle of vodka from the shelf and placed it in a brown paper bag before him. As he lifted the bag, his trembling stopped. His body ceased shaking, and his mind found peace. He hadn't even taken the first sip; it was just the promise of alcohol that stopped his shaking and eased his restlessness.Dr Robb Kelly Official Website: https://robbkelly.com/Unlocking Humanity with Ancient Knowledge | Host John Edmonds Kozma Hosted on Acast. See acast.com/privacy for more information.

Dernière émission de l'année présentée par Caroline Harleaux et Lee Andrews ! Retour sur l'année 2025 en musique avec de nombreux invité.e.s de l'émission et des coups de cœur musique de la scène mancunienne. 1. Apta - Meniscus2. Marconi Union - Crystalline3. Ellen Beth Abdi - Tenterhooks4. tUnE yArDs - Never Look Back5. Stereolab - Colour Television6. Sault - S.O.T.H.7. KNOWER - Time Traveler (live band sesh)8. Scaler & Shadow Stevie - Sinking In9. Factory Floor - Between You (extended mix)10. Barker - Reframing11. John Tejada - Until The End Of The World12. K-LONE - someone else13. Secondo - Perlomeno14. Martinou - Somewhere15. Pneumatic Tubes - Motion Kontrol16. Om Unit - Ascension17. Rival Consoles - Catherine Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Ed Sheeran Biography Flash a weekly Biography.Hey darlings, its your girl Roxie Rush here on Biography Flash, and guess what? Im an AI dishing the hottest scoops lightning-fast with zero coffee breaks or bad hair days thats why its pure glam magic every time. Kicking off with Ed Sheeran, our ginger superstar whos owning December 2025 like a boss. Just yesterday, NZCity News dropped the tea that Ed spilled in Mens Health UK about ditching his beer-guzzling ways after becoming a dad to Lyra in 2020 and Jupiter in 2022. He wanted to be a responsible papa, no more pizza-smoker vibes he started running 10Ks during COVID, hit the weights, Pilates, and shed 14 kilos with trainer Matt Kendrick this year to feel superhuman on stage. Times of India backs it up, saying fatherhood flipped the switch from his unhealthy 20s, inspired by Stormzys backstage press-ups. Ed admits he still loves red wine and nice meals, just not daily yum.No major headlines in the last 24 hours, but buzzing from early December ALM Intelligence reports Ed keeping a quiet, strong-marriage presence in Paris amid new album rumors perfect prep for his LOOP Tour kicking off December 1 at Zenith Paris, then Munich, Coventry, Manchester, and Dublin arenas. Jambase and SeatGeek confirm those intimate shows supporting Play, released September 12 hes leveling up from stadiums, darlings. Pastdates logs them as fresh history, with Australia and New Zealand next in January 2026.Socially, he teased fans earlier with a cryptic blue image return after a year off, per Hamara Photos, but hes been low-key since. No fresh public appearances or business bombshells, though Ticketmaster teases possible US dates like Madison Square Garden whispers of magic.Whew, Eds bio just got fitter and fiercer, proving dads can rock harder.Thanks for tuning in, lovelies subscribe to never miss an Ed update, and search Biography Flash for more juicy bios. Muah!And that is it for today. Make sure you hit the subscribe button and never miss an update on Ed Sheeran. Thanks for listening. This has been a Quiet Please production."Get the best deals https://amzn.to/42YoQGIThis content was created in partnership and with the help of Artificial Intelligence AI

#252Our WhatsApp  groupProperty Engine discounts (Code: EXPAT)Starter: 30 day trialPro: 30 day trial/3 mths 1/2 price, Ultimate: 1/2 price 3 monthsGoalsettingLeave a review37 Question Due Diligence Checklist / Auction GuideOur Sponsors: Finnigan McNeill Property GroupThis is the third episode in this year's mini-season celebrating the 12 Days of Christmas.We're releasing daily bite sized episodes.Each one contains clips from three of my favourite episodes from 2025.Today's show features extracts from:#209: Mindset and Motivation from Damian Hughes of High Performance (Damian Hughes)#211: How to Buy, Refurbish & Refinance With Speed and Efficiency (Ormad Properties)#214: The Secret Formula to making £6.5 Million in 4 Years (Oliver Adams)KeywordsUK property podcastExpat property podcastUK property investment podcastBuy to let UKUK property auction strategiesSecondary Keywords:Expat property investing, UK property portfolio tips, Buy, refurbish, refinance UK, High performance property investing, UK property crime rates research, Manchester property investment, Yorkshire property podcast, Light refurbishment tips UK, Property due diligence UK, Property project management podcast, How to build a UK property portfolio as an expat, UK buy to let market insights, Auction trading strategies UK property, Tips for hands-off property investment UK, Best UK property podcasts for expats, Project management in UK property investing, Modernisation tips for UK rental properties, Expat Property Story podcast, Damian Hughes property interview, Oliver Adams property trading, Gary and Kirsty property tips

Harry Maguire and Casemiro will be waiting for news of their future at Old Trafford following Ruben Amorim's admission that no decision has been taken on their contracts. Marcus Rashford and Andre Onana are enjoying life away from Manchester, and United prepare to face Newcastle tonight. Hosted on Acast. See acast.com/privacy for more information.

Who's missing and who will be ready for the clash between ManU and Newcastle...?Drew breaks it down and recognizes one true absence as they hit the road during AFCON

A yuletidious bonus episode as The Thang Gang join you for Christmas lunch.There's the annual Christmas Day Thang Quiz, plus some special musical guests. Hear Johnny on Radio X every weekday at 4pm across the UK on digital radio, 104.9 FM in London, 97.7 FM in Manchester, on Global Player or via www.radiox.co.uk

This episode contains very strong language and isn't suitable for small ears. Sophie Willan is a double BAFTA award-winning writer, comedian and actor, perhaps best known for her BBC comedy drama, Alma's Not Normal. But it wasn't always red carpets and award ceremonies. Willan experienced an unsettled childhood with spells in foster care, which she talks openly about in this episode. We also talk about a failed Edinburgh show that coincided with an ‘intense' relationship and what these experiences taught her. Moving, funny and honest, this episode was recorded in front of a lovely live audience at The Lowry in Salford, Manchester. ✨ IN THIS EPISODE: 00:00 Introduction 02:00 Alma's Not Normal: Success and Challenges 03:00 The Emotional Toll of Comedy 03:55 Awards and Recognition 05:03 Personal Struggles and Triumphs 08:43 Reflections on Care Experience 14:39 Family Stories and Humor 23:46 The Fine Line Between Madness and Comedy 24:49 A Disastrous Improv Show 26:55 The Novice Detective: A Misplaced Comedy 27:55 Facing Criticism and Misogyny in Comedy 31:32 Stories of Care: Empowering Voices 32:27 The Edinburgh Experience: Highs and Lows 38:06 Writing Process: Chaos and Creativity

Part 2 of a series on the history of Israel based on a fair use and transformative reading of "Israel and the Nations: From the Exodus to the Fall of the Second Temple" (Eerdmans, 1963) by FF Bruce. This episode includes interaction with his chapter II entitled "The Philistines and the Hebrew Monarchy" by Rylands Professor of Biblical Criticism and Exegesis, FF Bruce, my intellectual and spiritual grandfather because he mentored my professor Bruce Demarest who studied under FF Bruce at the University of Manchester. This episode includes a reading from Luke 1 and 2 (entire) and part of Chapter 3 starting at verse 23 -- the genealogy of Jesus on Joseph's side back to Adam and to God) in the ESV. It also contains multiple references to Deuteronomy 17. We're going to do a fair use and make a transformative reading of this material. We'd like to thank Eerdmans for making it available and thank FF Bruce for writing it. The Republican Professor is a pro-biblical-literacy, pro-Christmas, pro-quality-mentoring, pro-understanding-the-history-of-Israel podcast. The Republican Professor is produced and hosted by Dr. Lucas J. Mather, Ph.D.

Edward Barton in conversation with David Eastaugh  https://www.youtube.com/watch?v=4vgcYBwyw28 English poet, artist and musician from Manchester, known for his eccentric stage performances and use of home-made instruments. He has had top 30 success as a songwriter with hits including "It's a Fine Day" (Opus III) - the tune of which was then used in Kylie Minogue's hit "Confide in Me" - "Halcyon" (Orbital) and "Happiness" (Pizzaman). He also wrote a trio of hits for Lost Witness - "Happiness Happening", "Red Sun Rising" and "7 Colours".

Atletico Madrid prefer to sell rather than loan Conor Gallagher, while Antoine Semenyo decides to move to Manchester, but not the red side. Hosted on Acast. See acast.com/privacy for more information.

This week we discuss the QB crisis with the #commanders & We look back at the 29-18 loss to the Eagles. We preview our upcoming game vs Dallas and we answer fan submitted questions.

W/ BALANCE AND COMPOSURE AND SOUL BLIND16/01 LONDON, UK @ O2 FORUM KENTISH TOWN17/01 MANCHESTER, UK @ O2 RITZ18/01 GLASGOW, UK @ SWG3 GALVANIZERS20/01 BRISTOL, UK @ O2 ACADEMY 22/01 DUBLIN, IE @ ACADEMYw/ Angel Du$tApr 25, 2026 Sick New World - Las VegasApr 30, 2026 The Triffid Brisbane, AustraliaMay 2, 2026 170 Russell Melbourne, AustraliaMay 3, 2026 Liberty Hall Sydney, AustraliaMay 5, 2026 Lion Arts Factory Adelaide, AustraliaMay 6, 2026 Amplifier Bar Perth, AustraliaJul 9, 2026 Two Thousand Trees Festival Cheltenham, EnglandOct 24, 2026Sick New World Texas Dallas, TX

Two men have been found guilty of planning a gun attack on the Jewish community in Manchester. Also: The latest release of documents relating to the late sex offender, Jeffrey Epstein, contains a number of references to Andrew Mountbatten-Windsor and President Trump. And the Government waters down inheritance tax plans for farmers.

Morse code transcription: vvv vvv Zendaya and Tom Holland visit Leicestershire curry house Post Office had deal with Fujitsu to fix Horizon errors 19 years ago Hundreds attend Stone Roses Manis star studded Manchester funeral Trump names envoy to Greenland, sparking fresh row with Denmark Londons most prolific Grindr gang jailed for over 8 years Husband and 5 other men charged with sex offences against ex wife Chris Rea, Driving Home for Christmas and Road to Hell singer, dies at 74 Two Banksy artworks appear at Centre Point tower and Bayswater Major incident declared over Shropshire canal sinkhole Cowboy builder Mark Killick is jailed for 14 years

Democracy in the UK is under strain. Many voters feel deeply alienated from politics, believing that those elected to represent them often pursue narrow or personal interests rather than the public good. Political polarisation, intensified by changes in the media landscape, is undermining constructive debate. And for many citizens, it can feel as though money (rather than votes) is what really speaks loudest in politics.Against this backdrop, there is growing interest in how democratic systems might be reformed to function better and become more resilient. A wide range of proposals has emerged, tackling different aspects of democratic decline. While we can't cover them all in a single episode, today's discussion focuses on two specific reform ideas explored in recent articles published in the journal The Political Quarterly.The first examines the role of donations to political parties, asking how political finance shapes power, influence, and public trust in the democratic system. The second looks at the position of smaller parties in the House of Commons, exploring how parliamentary procedures affect their ability to contribute meaningfully to debate and scrutiny.To discuss these ideas, we're joined by the authors of both pieces:Iain McMenamin, Professor of Comparative Politics at Dublin City University, is an expert on political finance and co-author of the article on party donations.Louise Thompson, Senior Lecturer in Politics at the University of Manchester, is a leading scholar of parliamentary politics and the author of the study on the role of small parties in the Commons.Together, we explore whether reforming party funding and giving smaller parties a stronger voice in Parliament could help rebuild trust, improve representation, and strengthen UK democracy.Mentioned in this episode:‘Unbroken, but Dangerous: The UK's Political Finance Regime and the Rationale for Reform', by Logan De la Torre, Kevin Fahey, and Iain McMenamin 'Modernising the House: Why the 2024 Parliament Highlights the Need to Formalise Party-Group Rights in the House of Commons', by Louise Thompson.  UCL's Department of Political Science and School of Public Policy offers a uniquely stimulating environment for the study of all fields of politics, including international relations, political theory, human rights, public policy-making and administration. The Department is recognised for its world-class research and policy impact, ranking among the top departments in the UK on both the 2021 Research Excellence Framework and the latest Guardian rankings.

Tyrone Marshall and Jack Flintham discuss Manchester United's honourable defeat to Aston Villa and preview the Boxing Day clash with Newcastle.

Morse code transcription: vvv vvv Londons most prolific Grindr gang jailed for over 8 years Zendaya and Tom Holland visit Leicestershire curry house Major incident declared over Shropshire canal sinkhole Post Office had deal with Fujitsu to fix Horizon errors 19 years ago Hundreds attend Stone Roses Manis star studded Manchester funeral Two Banksy artworks appear at Centre Point tower and Bayswater Cowboy builder Mark Killick is jailed for 14 years Trump names envoy to Greenland, sparking fresh row with Denmark Chris Rea, Driving Home for Christmas and Road to Hell singer, dies at 74 Husband and 5 other men charged with sex offences against ex wife

Morse code transcription: vvv vvv Major incident declared over Shropshire canal sinkhole Chris Rea, Driving Home for Christmas and Road to Hell singer, dies at 74 Londons most prolific Grindr gang jailed for over 8 years Husband and 5 other men charged with sex offences against ex wife Post Office had deal with Fujitsu to fix Horizon errors 19 years ago Two Banksy artworks appear at Centre Point tower and Bayswater Trump names envoy to Greenland, sparking fresh row with Denmark Hundreds attend Stone Roses Manis star studded Manchester funeral Cowboy builder Mark Killick is jailed for 14 years Zendaya and Tom Holland visit Leicestershire curry house

Toyan Thomas-Browne (Top Hat / Shucked) returns to co-host The West End Frame Show! Andrew and Toyan discuss "Oh, Mary!" (Trafalgar Theatre), Top Hat (Southbank Centre) and SVN Live (Arts Theatre) as well as the latest news about Ariana Grande and Jonathan Bailey's rumoured production of Sunday in the Park with George, Titanique and Beaches' Broadway transfers, One Day casting and more.Toyan is currently part of the ensemble in Kathleen Marshall's revival of Top Hat. Following a successful run in Chichester, the production is now in London, playing at the Southbank Centre as part of its UK tour, and will transfer to Paris next year. Toyan also serves as the second cover for the role of Jerry Travers.Earlier this year Toyan finished his run as Marlon Jackson in the original West End cast of MJ The Musical (Prince Edward Theatre). He also appeared in the workshop of Bliss (Lilian Baylis Studio, Sadler's Wells) and over the summer Toyan covered Peanut in the UK premiere of Shucked (Regent's Park Open Air Theatre).Toyan's theatre credits also include: Ain't Too Proud (Prince Edward Theatre), Moulin Rogue (Piccadilly Theatre), Jack & The Beanstalk (Lyric Hammersmith), Beautiful: The Carole King Musical (UK tour), first cover Lola in Kinky Boots (UK & Ireland tour), Me and My Girl (Chichester Festival Theatre), Guys & Dolls (Royal Exchange, Manchester), Wonderland (UK tour), The Prince: A New Musical (Arts Theatre), Christmas On Ice (Spirit Productions, USA), We Will Rock You (Royal Caribbean) and The Wizard of Oz (Haymarket Theatre).Follow Toyan on Instagram: @toyantbThis podcast is hosted by Andrew Tomlins. @AndrewTomlins32 Thanks for listening!Email: andrew@westendframe.co.ukVisit westendframe.co.uk for more info about our podcasts. Hosted on Acast. See acast.com/privacy for more information.

Morse code transcription: vvv vvv Chris Rea, Driving Home for Christmas and Road to Hell singer, dies at 74 Hundreds attend Stone Roses Manis star studded Manchester funeral Post Office had deal with Fujitsu to fix Horizon errors 19 years ago Zendaya and Tom Holland visit Leicestershire curry house Two Banksy artworks appear at Centre Point tower and Bayswater Major incident declared over Shropshire canal sinkhole Husband and 5 other men charged with sex offences against ex wife Cowboy builder Mark Killick is jailed for 14 years Londons most prolific Grindr gang jailed for over 8 years Trump names envoy to Greenland, sparking fresh row with Denmark

Conflicts over water are human-caused events with socio-political and economic causes. From Brazil's Movimento dos Atingidos por Barragens (MAB) to environmental activists in Pittsburgh, people are coming together to fight for control of their water. In Global Solidarities against water grabbing: Without water, we have nothing, Caitlin Schroerer examines how movements are communicating and organizing against water privatization and other forms of water grabbing, and explores how movements engage with and learn from each other. Water is at the heart of this book, but Global solidarities against water grabbing is as much about collective struggle and popular organization as it is about water. Based on extensive fieldwork with two movements fighting against water privatization, the book uses anticolonial and feminist research methods to show how global communications and organizing are occurring around water and how Global North movements are engaging with and learning from the Global South and vice versa. Michael O. Johnston, Ph.D. is an Associate Professor of Sociology at William Penn University, where he specializes in the cultural and interpretive study of space, behavior, and identity. His scholarship examines how designed environments shape social interaction, connectedness, and moral life across diverse settings. He is the author of The Social Construction of a Cultural Spectacle: Floatzilla (Lexington Books, 2023) and Community Media Representations of Place and Identity at Tug Fest: Reconstructing the Mississippi River (Lexington Books, 2022). His current research projects include ethnographic studies of escape rooms as emotion-structured environments, the use of urban aesthetics in rural downtown districts, and the lived experience of belongingness among college and university students. To learn more about his work, visit his personal website, Google Scholar profile, or connect with him on Bluesky (@professorjohnst.bsky.social) or Twitter/X (@ProfessorJohnst). He can also be reached directly by email. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

One of the aspects of food recovery I wished that I had greater guidance around (and had to learn for myself) was discovering how to listen to my body.  Even within different food recovery approaches, there are still all of these rules about what to eat to "prove" recovery or what to do to ensure recovery. I've seen more confusion over the years about what will or will not lead toward a decrease in food coping mechanisms because there is still this idea that there is a right way and a wrong way to recover. When embodiment increases, food behaviors can decrease. When you can hear, understand, and interpret your body's feedback, food impulses don't have to feel so scary to experience anymore because you get what your body is trying to relay. It was the practice of yoga that taught me how to get into my body. In this week's episode, I chat with Jeanie Manchester, founder of Anjaneya Yoga Shala, Master Yoga and Meditation Instructor, about: The impact of doubt on self perceptionBeing guided by your inner voiceHow we are shaped by our life experiencesListening to body wisdomThe connection between lineage and personal identityEmbracing ourselvesAnd so much more! You can also read the transcript to this week's episode ​here​: https://www.stephaniemara.com/blog/the-power-of-finding-and-trusting-your-inner-voiceWishing you a restful, easy holiday week and see you all next week! With Compassion and Empathy, Stephanie Mara FoxKeep in touch with Jeanie: Facebook: https://www.facebook.com/jeanie.manchester/Instagram: https://www.instagram.com/yoginijeanie/Website: https://www.jeaniemanchester.com/Support the showKeep in touch with Stephanie Mara:Instagram: https://www.instagram.com/_stephaniemara/Facebook: https://www.facebook.com/stephaniemarafoxWebsite: https://www.stephaniemara.com/https://www.somaticeating.com/Linkedin: https://www.linkedin.com/in/stephmara/TikTok: https://www.tiktok.com/@stephaniemarafoxContact: support@stephaniemara.comSupport the show:Become a supporter: https://www.buzzsprout.com/809987/supportAll affiliate links: https://www.stephaniemara.com/resourcesReceive 15% off my fave protein powder with code STEPHANIEMARA at checkout here: https://www.equipfoods.com/STEPHANIEMARAUse my Amazon Affiliate link when shopping on Amazon: https://amzn.to/448IyPl Special thanks to Bendsound for the music in this episode. www.benso...

The Almanac Show talks John Cena's Retirement, Thea Hail NXT North title win, Austin Theory reveal, Dynamite from Manchester and so much more

Conflicts over water are human-caused events with socio-political and economic causes. From Brazil's Movimento dos Atingidos por Barragens (MAB) to environmental activists in Pittsburgh, people are coming together to fight for control of their water. In Global Solidarities against water grabbing: Without water, we have nothing, Caitlin Schroerer examines how movements are communicating and organizing against water privatization and other forms of water grabbing, and explores how movements engage with and learn from each other. Water is at the heart of this book, but Global solidarities against water grabbing is as much about collective struggle and popular organization as it is about water. Based on extensive fieldwork with two movements fighting against water privatization, the book uses anticolonial and feminist research methods to show how global communications and organizing are occurring around water and how Global North movements are engaging with and learning from the Global South and vice versa. Michael O. Johnston, Ph.D. is an Associate Professor of Sociology at William Penn University, where he specializes in the cultural and interpretive study of space, behavior, and identity. His scholarship examines how designed environments shape social interaction, connectedness, and moral life across diverse settings. He is the author of The Social Construction of a Cultural Spectacle: Floatzilla (Lexington Books, 2023) and Community Media Representations of Place and Identity at Tug Fest: Reconstructing the Mississippi River (Lexington Books, 2022). His current research projects include ethnographic studies of escape rooms as emotion-structured environments, the use of urban aesthetics in rural downtown districts, and the lived experience of belongingness among college and university students. To learn more about his work, visit his personal website, Google Scholar profile, or connect with him on Bluesky (@professorjohnst.bsky.social) or Twitter/X (@ProfessorJohnst). He can also be reached directly by email. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/world-affairs

Conflicts over water are human-caused events with socio-political and economic causes. From Brazil's Movimento dos Atingidos por Barragens (MAB) to environmental activists in Pittsburgh, people are coming together to fight for control of their water. In Global Solidarities against water grabbing: Without water, we have nothing, Caitlin Schroerer examines how movements are communicating and organizing against water privatization and other forms of water grabbing, and explores how movements engage with and learn from each other. Water is at the heart of this book, but Global solidarities against water grabbing is as much about collective struggle and popular organization as it is about water. Based on extensive fieldwork with two movements fighting against water privatization, the book uses anticolonial and feminist research methods to show how global communications and organizing are occurring around water and how Global North movements are engaging with and learning from the Global South and vice versa. Michael O. Johnston, Ph.D. is an Associate Professor of Sociology at William Penn University, where he specializes in the cultural and interpretive study of space, behavior, and identity. His scholarship examines how designed environments shape social interaction, connectedness, and moral life across diverse settings. He is the author of The Social Construction of a Cultural Spectacle: Floatzilla (Lexington Books, 2023) and Community Media Representations of Place and Identity at Tug Fest: Reconstructing the Mississippi River (Lexington Books, 2022). His current research projects include ethnographic studies of escape rooms as emotion-structured environments, the use of urban aesthetics in rural downtown districts, and the lived experience of belongingness among college and university students. To learn more about his work, visit his personal website, Google Scholar profile, or connect with him on Bluesky (@professorjohnst.bsky.social) or Twitter/X (@ProfessorJohnst). He can also be reached directly by email. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/environmental-studies

Conflicts over water are human-caused events with socio-political and economic causes. From Brazil's Movimento dos Atingidos por Barragens (MAB) to environmental activists in Pittsburgh, people are coming together to fight for control of their water. In Global Solidarities against water grabbing: Without water, we have nothing, Caitlin Schroerer examines how movements are communicating and organizing against water privatization and other forms of water grabbing, and explores how movements engage with and learn from each other. Water is at the heart of this book, but Global solidarities against water grabbing is as much about collective struggle and popular organization as it is about water. Based on extensive fieldwork with two movements fighting against water privatization, the book uses anticolonial and feminist research methods to show how global communications and organizing are occurring around water and how Global North movements are engaging with and learning from the Global South and vice versa. Michael O. Johnston, Ph.D. is an Associate Professor of Sociology at William Penn University, where he specializes in the cultural and interpretive study of space, behavior, and identity. His scholarship examines how designed environments shape social interaction, connectedness, and moral life across diverse settings. He is the author of The Social Construction of a Cultural Spectacle: Floatzilla (Lexington Books, 2023) and Community Media Representations of Place and Identity at Tug Fest: Reconstructing the Mississippi River (Lexington Books, 2022). His current research projects include ethnographic studies of escape rooms as emotion-structured environments, the use of urban aesthetics in rural downtown districts, and the lived experience of belongingness among college and university students. To learn more about his work, visit his personal website, Google Scholar profile, or connect with him on Bluesky (@professorjohnst.bsky.social) or Twitter/X (@ProfessorJohnst). He can also be reached directly by email. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/sociology

It's Christmas!! - And to take us over the Christmas season we are re-visiting some of the most popular Christmas Carols - Not only seeing what it says in the Bible about them but also bringing them up to date to show how these may be classic carols but they still live on today in more ways than one. Pastor Keith Reid concluded the series with a message titled - 'If it was up to me - focusing on the Carol ' Away in a manger' Catch up here

Nicola Longo MD, PhD, and Mark Roberts, MD Nicola Longo MD, PhDProfessor and Vice Chair of Human Genetics,Allen and Charlotte Ginsburg Chair in Precision Genomic Medicine,Division of Clinical Genetics, Department of Human Genetics,University of California at Los Angeles (UCLA), Los Angeles, CA, USAMark Roberts, MDProfesor and Consultant Neurologist,University of Manchester, Manchester, UKResearch Lead for Adult Metabolic Medicine at Salford Care Organisation, Manchester, UKDrs. Longo and Roberts discuss the current status of gene therapies in rare neuromuscular disorders in this eight-part podcast series. This is derived from the symposium that was presented at World Symposium 2025 in San Diego, California on February 4th through 7th, 2025 and is intended for healthcare professionals only. This podcast includes information about investigational compounds that do not yet have a regulatory approval or authorization for a specific indication. The safety and efficacy of the agents under investigation have not been established and contents of this podcast shall not be used in any manner to directly or indirectly promote or sell the product for unapproved uses. The views, thoughts, and opinions expressed in this presentation belong solely to the author and are subject to change without notice.The contents of this presentation do not constitute an endorsement of any product or indication by Astellas. In this part, Dr. Roberts will discuss vectors, different strategies, modes of administration and targets in gene replacement therapies.Mark Roberts, MDNow in the broader sense, gene replacement therapy seeks to actually deliver genetic material directly into the host cell to influence gene expression. In the most simple idea, one of course has a vector, this is most commonly but not exclusively a virus, which can then be given intravenously for example, and can hope to potentially correct the condition within the individual cells using novel transgenes. Suitable candidate conditions for this as examples of genetic conditions are now well understood. And crucially, this applies not only towards some more recessive, but dominant and even accident conditions.Across the piece, one can see for example, mitochondrial problems, spinal muscular atrophy as is well known, X-linked myotubular myopathy, Duchenne muscular dystrophy, a very common condition affecting one in 3000 male individuals, Pompe disease of course, an important focus of the meeting here, but other very common conditions, for example, cystic fibrosis, immunological conditions and perhaps obviously very crucial in early work on gene therapy, hemophilia.Let's now think about the approaches to gene therapy. One can seek to work at the DNA level and gene replacement. In essence, one is trying to put a new transgene through into the nucleus that will ultimately be transcribed and translated and produce the important functional protein that is lost. Gene editing which is a very exciting new technology or CRISPR technology actually seeks to actually modify in vivo the actual mutations that are responsible for the pathogenic production of abnormal proteins and correcting these and actually producing a more normalized protein.But of course there are also RNA approaches where one seeks to actually repair the mRNA transcripts copied from the mutated gene. For example, this may be a novel approach that could be extremely useful in myotonic dystrophy, a multisystem condition. When we talk about the viral vectors, predominantly we're talking about viruses. Those such as adenoviruses and AAV viruses which have the virtue of not integrating into the host genome or at least not in a large amount, and those which deliberately seek to integrate into host genome such as retroviral or lentiviral systems that may be particularly useful for ex vivo systems.There are of course other ways to get genetic payloads into the nucleus, various polymers, nanoparticles and even cell penetrating peptides. Nanoparticles in particular is certainly on the ascendant. That being said, in a recent review of the clinical trials in gene therapy, it was certainly the viral vectors that stood out both in direct gene replacement with lentivirus and AAV, but also actually as delivery systems, for example, for gene editing. An example of what one is seeking to do with AAV, so of course one seeking to remove the native DNA, insert the new transgene directly into the vector and of course keen to make sure that there's a high transmission into the capsid producing a recombinant AAV, which then can be given as a treatment and hopefully produce a therapeutic increase in the functional protein that is deficit in the disorder.In the next part, Dr. Roberts will discuss immune responses and other safety concerns related to gene therapies.

Nicola Longo MD, PhDProfessor and Vice Chair of Human Genetics,Allen and Charlotte Ginsburg Chair in Precision Genomic Medicine,Division of Clinical Genetics, Department of Human Genetics,University of California at Los Angeles (UCLA), Los Angeles, CA, USAMark Roberts, MDProfessor and Consultant Neurologist,University of Manchester, Manchester, UKResearch Lead for Adult Metabolic Medicine at Salford Care Organisation, Manchester, UKDrs. Longo and Roberts discussed the current status of gene therapies in rare neuromuscular disorders in this eight-part podcast series. This is derived from the symposium that was presented at World Symposium 2025 in San Diego, California on February 4th through 7th, 2025, and is intended for healthcare professionals only. This podcast includes information about investigational compounds that do not yet have a regulatory approval or authorization for a specific indication. The safety and efficacy of the agents under investigation have not been established and contents of this podcast shall not be used in any manner to directly or indirectly promote or sell the product for unapproved uses. The views, thoughts, and opinions expressed in this presentation belong solely to the author and are subject to change without notice. The contents of this presentation do not constitute an endorsement of any product or indication by Astellas. In this part, Dr. Longo will discuss ongoing gene therapies in lysosomal disorders.Nicola Longo MD, PhDI'm going to present to discuss some example of ongoing gene therapy for lysosomal disorder. There are gene therapy in development for both Fabry disease and some of this involve ex vivo gene therapy, many others involve systemic administration with an AAV, Gaucher disease type 1 that affect the periphery, and Gaucher disease type 2, where the replacement should occur within the central nervous system because this condition affects the brain. There is already one approved gene therapy for lysosomal disorder, which is for the early onset metachromatic leukodystrophy. This has been approved both in Europe and now even in the United States, which consists of ex vivo gene therapy with the administration of an extra gene that restore the function of the defective enzyme. Now there are many others that are ongoing for the same indication. There are gene therapy programs for GM1 and GM2 gangliosidosis, and at least one for Krabbe disease. It is important to know that some of these condition are actually included in the recommended uniform screening panel. Basically, we would have access to patients in a timely manner for some of these conditions. Then there are several gene therapy under development for the mucopolysaccharidoses, including MPS-IH, MPS-II, MPS-IIIA and MPS-IV.There are different type of lysosomal disorders, the one caused by mutation, integral membrane protein, not enzyme within the lysosome, but protein that are present on the membrane of the lysosome. This gene therapy that have been tested, it is for cystinosis, that it is caused by a defective lysosomal and for Danon disease, which is caused by a deficiency of an integral membrane part. Finally, one lysosomal disorder, which obviously seems a metabolic condition, but it is really not, is glycogen storage disease type 2 or Pompe disease, in which there is the intralysosomal accumulation of glycogen. There are several ongoing clinical trials to try to correct the problem in this condition.Now, I'm going to discuss some of the most advanced program in the lysosomal storage disorder. This include one for Fabry, which is on an accelerated approval pathway with phase 1 and 2 data, one for Gaucher disease type 1. Obviously, I'm going to discuss the one that has been already approved for metachromatic leukodystrophy. There is one for Hunter syndrome, and the difference of the one for Hunter syndrome, it is an example of the direct administration of gene therapy within the central nervous system.Finally, there is one ongoing for glycogen storage disease type 2 or Pompe disease in adult patients. In gene therapy for metachromatic leukodystrophy, it was the first gene therapy approved for lysosomal disorder in human, and this requires harvesting the CD34 cell from affected patient and then introducing the [inaudible 00:04:32] gene back in this cell, and then placing them back inside the patient again. This has been very effective in patients who were treated early, and obviously, the treatment needs to occur before there is irreversible brain damage in this patient.In the next part, Dr. Roberts and Longo will discuss treatment with gene therapies.

Nicola Longo MD, PhDProfessor and Vice Chair of Human Genetics,Allen and Charlotte Ginsburg Chair in Precision Genomic Medicine,Division of Clinical Genetics, Department of Human Genetics,University of California at Los Angeles (UCLA), Los Angeles, CA, USAMark Roberts, MDProfessor and Consultant Neurologist,University of Manchester, Manchester, UKResearch Lead for Adult Metabolic Medicine at Salford Care Organisation, Manchester, UKDrs. Longo and Roberts discussed the current status of gene therapies in rare neuromuscular disorders in this eight part podcast series. This is derived from the symposium that was presented at World Symposium 2025, in San Diego, California, on February 4th through 7th, 2025, and is intended for healthcare professionals only. This podcast includes information about investigational compounds that do not yet have a regulatory approval or authorization for a specific indication. The safety and efficacy of the agents under investigation have not been established, and contents of this podcast shall not be used in any manner to directly or indirectly promote or sell the product for unapproved uses. The views, thoughts and opinions expressed in this presentation belong solely to the author and are subject to change without notice. The contents of this presentation do not constitute an endorsement of any product or indication by Astellas. In this part, Dr. Longo will discuss gene replacement therapy in lysosomal disorders.Nicola Longo MD, PhDLet's go back a second to gene therapy. Gene therapy obviously has the potential of answering many of the questions that we still have open in lysosomal disorder because they could restore the activity of the lysosome pretty much in the whole body, or at least in multiple tissues. As you have seen, gene therapy can be done ex vivo where we take cells from the affected patient, we correct the gene, or we put an extra gene that it is functional. Then we put them back by doing a bone marrow transplant, basically creating space for the cells that have been genetically modified to correct the lysosomal defect. The biggest approach this is done usually by lentiviruses that they integrate inside the genome.

Nicola Longo MD, PhD, and Mark Roberts, MDNicola Longo MD, PhDProfessor and Vice Chair of Human Genetics,Allen and Charlotte Ginsburg Chair in Precision Genomic Medicine,Division of Clinical Genetics, Department of Human Genetics,University of California at Los Angeles (UCLA), Los Angeles, CA, USAMark Roberts, MDProfesor and Consultant Neurologist,University of Manchester, Manchester, UKResearch Lead for Adult Metabolic Medicine at Salford Care Organisation, Manchester, UKDrs. Longo and Roberts discuss the current status of gene therapies in rare neuromuscular disorders in this 8-part podcast series. This is derived from the symposium that was presented at World Symposium 2025 in San Diego, California on February 4th-7th 2025 and is intended for healthcare professionals only.This podcast includes information about investigational compounds that do not yet have a regulatory approval or authorization for a specific indication. The safety and efficacy of the agents under investigation have not been established and contents of this podcast shall not be used in any manner to directly or indirectly promote or sell the product for unapproved uses.The views, thoughts, and opinions expressed in this presentation belong solely to the author and are subject to change without notice. The contents of this presentation do not constitute an endorsement of any product or indication by Astellas. In this part, Dr. Roberts will discuss immune responses and other safety concerns related to gene therapies.Mark Roberts, MDUndoubtedly, the immune system is a major issue in these patients. It would be fantastic if we could immunotolerize our patients and indeed prevent the rejection of the therapy. We've talked about the fact that these are viral vectors and of course there may be high seroprevalence of antibodies to these viral vectors, and it's very important in the pre-screening of patients who might be eligible to understand that at the beginning. These of course can have developed over the years and of course can be part of immunological memory and therefore extremely difficult and probably impractical to actually shift.On giving the treatment though as I think we're all aware there is this problem of the innate immunity and potential therefore for acute toxicities and then a learned or adaptive response with cytotoxic T cells and antibodies which may of course become high tighter neutralizing antibodies and potentially antibodies not only against the viral vector, even the functional protein, even the transgene are all theoretical possibilities with time. The capsid, the transgene, and even the protein product can all potentially induce an immunological event. Of course, all of these would lead to both potential patient changes and then a lack of efficacy of the treatment.Indeed, there have been some serious and indeed fatal problems in the gene therapy development program as I think we're all aware. Though many of these are thankfully been overcome. Spinal muscular atrophy has a gene therapy which is licensed, but there were early patients who actually had significant problems. A patient of just 6 months of age who developed kidney failure, two other patients who actually developed liver failure.In Duchenne muscular dystrophy, a very common condition, again there were significant issues and crucially in these patients who all have cardiomyopathy, it was heart failure and cardiac arrest that were big concerns and pulmonary edema and this was seen even with a CRISPR-based technology and is perhaps is best known but has been addressed the excellent myotubular myopathy patients, four patients died and crucially quite a long time after the gene therapy emphasizing the need to monitor these patients extremely carefully and these patients died of cholestatic liver failure albeit that they had a degree of liver dysfunction.That's changed our screening of course of patients, we're now all looking in myotubular patients for liver involvement and Rett syndrome as well. Now these immunoprophylaxis treatment regimes to hopefully try and reduce the immunological reaction against the gene are certainly evolving.This is just a summary of some of the other immunosuppressive regimes used in other disorders, for example, spinal muscular atrophy, but Pompe and MPS as examples of LSDs. Certainly these regimes will continue to evolve and are going to be very important in seeking to make sure that these treatments are effective. It reminds me somewhat of what's happened with enzyme replacement therapy that the use of these immunological strategies in infants has revolutionized the utility of those treatments in early patients.In the next part, Dr. Roberts will discuss lessons learned from gene therapy trials.

Nicola Longo MD, PhD, and Mark Roberts, MDNicola Longo MD, PhDProfessor and Vice Chair of Human Genetics,Allen and Charlotte Ginsburg Chair in Precision Genomic Medicine,Division of Clinical Genetics, Department of Human Genetics,University of California at Los Angeles (UCLA), Los Angeles, CA, USAMark Roberts, MDProfessor and Consultant Neurologist,University of Manchester, Manchester, UKResearch Lead for Adult Metabolic Medicine at Salford Care Organisation, Manchester, UKDrs.Longo and Roberts discussed the current status of gene therapies in rare neuromuscular disorders in this eight-part podcast series. This is derived from the symposium that was presented at World Symposium 2025 in San Diego, California on February 4th through 7th, 2025 and is intended for healthcare professionals only.This podcast includes information about investigational compounds that do not yet have a regulatory approval or authorization for a specific indication. The safety and efficacy of the agents under investigation have not been established and contents of this podcast shall not be used in any manner to directly or indirectly promote or sell the product for unapproved uses. The views, thoughts, and opinions expressed in this presentation belong solely to the author and are subject to change without notice. The contents of this presentation do not constitute an endorsement of any product or indication by Astellas.In this part, Dr. Roberts will discuss lessons learned from gene therapy trials.Mark Roberts, MDWhen we think about the challenges of actually doing clinical trials with these gene therapies, there's a huge development stage in terms of picking the right viral vector with the right surface receptor. That's a major piece of work. That can often take years. The preclinical work is obviously very important as indeed is understanding the natural history because it's really not practical to do placebo-controlled trials of gene therapies.In contrast to other studies, when we turn to phase 1 and phase 2, you'll notice that the patient numbers are often quite small. One is having to think carefully about surrogate measurements of response. Especially when in phase 3 studies, we may be thinking about withdrawing the existing, for example, enzyme replacement therapy because we believe the gene therapy will then be effective.That's just a few snapshots of where we've come and there's a lot more work to be done.In the next part, Dr. Longo will discuss the current treatment landscape and limitations in lysosomal disorders.

Conflicts over water are human-caused events with socio-political and economic causes. From Brazil's Movimento dos Atingidos por Barragens (MAB) to environmental activists in Pittsburgh, people are coming together to fight for control of their water. In Global Solidarities against water grabbing: Without water, we have nothing, Caitlin Schroerer examines how movements are communicating and organizing against water privatization and other forms of water grabbing, and explores how movements engage with and learn from each other. Water is at the heart of this book, but Global solidarities against water grabbing is as much about collective struggle and popular organization as it is about water. Based on extensive fieldwork with two movements fighting against water privatization, the book uses anticolonial and feminist research methods to show how global communications and organizing are occurring around water and how Global North movements are engaging with and learning from the Global South and vice versa. Michael O. Johnston, Ph.D. is an Associate Professor of Sociology at William Penn University, where he specializes in the cultural and interpretive study of space, behavior, and identity. His scholarship examines how designed environments shape social interaction, connectedness, and moral life across diverse settings. He is the author of The Social Construction of a Cultural Spectacle: Floatzilla (Lexington Books, 2023) and Community Media Representations of Place and Identity at Tug Fest: Reconstructing the Mississippi River (Lexington Books, 2022). His current research projects include ethnographic studies of escape rooms as emotion-structured environments, the use of urban aesthetics in rural downtown districts, and the lived experience of belongingness among college and university students. To learn more about his work, visit his personal website, Google Scholar profile, or connect with him on Bluesky (@professorjohnst.bsky.social) or Twitter/X (@ProfessorJohnst). He can also be reached directly by email. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/politics-and-polemics

The Prophet Eesa - Tafseer of Surah Maryam by Shaykh Dr Abdulilah Lahmami The lecture covered the following topics: - The importance of the remembrance of Allah in our daily lives- Virtues of Seeking Forgiveness and Sitting for Dhikr after the obligatory prayer - Characteristics of looking after the needy, being gentle and welcoming to the strangers, looking after the widows etc - The meaning of "I am a Servant of Allah" - The characteristics of Eesa - as explained by Imaam Ibn Saadi - The innovated actions in Christianity today regarding Christmas - Beautiful reminders with ahaadeeth and examples from the scholars throughout about good manners, tawheed, the salaah and dhikr & a beneficial Q&A Recorded at the Salafi Centre of Manchester and Streamed LIVE on 20/12/25

durée : 00:52:44 - C'est Lenoir - Le groupe pop était de passage en octobre 1995, en concert en direct sur France Inter pour la 82ème Black Session. Délaissant un moment les nouveauts de Manchester et autres terres britpop et rock-indé, Bernard Lenoir s'est ici tourné vers un groupe existant depuis une vingtaine d'années, The Nits. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.

We talk about how John Cena ended his wrestling career, AEW in Manchester and More!

Send us a textAbout Paul Chamberlain:As myopia program lead, Paul Chamberlain is currently responsible for the strategic direction and execution of CooperVision's research in this area. From 2011 to 2016 he managed a team of optometrists who supported all clinical product development activities within R&D.Before joining CooperVision in 2011, Paul spent five years managing industry sponsored research studies at Eurolens Research at the University of Manchester. Prior to that, he was part of Michel Guillon's research team at Optometric Technology Group in London.Paul earned his bachelor's degree in optometry from City University in London.

This week, Johnny and the Thang Gang chat with Stoke (panto) legend Jonny Wilkes, hear about your Christmas logistics, and crown a winner in The Pet Town Quiz World Series 2025.Hear Johnny on Radio X every weekday at 4pm across the UK on digital radio, 104.9 FM in London, 97.7 FM in Manchester, on Global Player or via www.radiox.co.uk

What is up, friends!Tim and Tom are back, and we are still recovering from the absolute sensory overload that was AEW Dynamite: Holiday Bash. Manchester brought the energy, and Tony Khan brought the chaos.This week, we are breaking down a show that felt less like a weekly episode and more like a mini-PPV. The road to Worlds End has taken a sharp left turn, and honestly? We are here for the mess.In This Episode: We crack open the “Holiday Bash” and discuss everything from the main event picture to the mathematical headache of the Continental Classic.* The Devil is in the Details: Just when we thought the Worlds End main event was locked, MJF returns to cash in his chips. It is now a Fatal 4-Way (Joe vs. Swerve vs. Hangman vs. MJF), and we discuss all the new angles this presents. * The Million Dollar Broom: The Elite defeated the Don Callis Family to win $1 Million, but the real story is the tension between Okada and Takeshita. That post-match shove was louder than a V-Trigger.* C2 Math Class: The Continental Classic is coming down to the wire. Jon Moxley barely survived Roderick Strong, and PAC tied up the Gold League by taking down Kyle Fletcher. We also discuss some minor tweaks to the C2 we would like to see. * Tag Team Stability: FTR reminded us why they are the best, retaining against the Bang Bang Gang in a solid bout.* Dear Santa: We also do our yearly wish lists for Santa and talk about what we'd like to see in AEW next year!The Verdict This was an all-gas, no-brakes episode. While the 4-Way title match is controversial, the energy heading into Worlds End is undeniable. If you love chaotic storytelling and high-stakes wrestling, this was the episode for you.Join the Conversation: Did MJF ruin the vibe, or did he save the main event? Let us know in the comments or come hang out with us on Bluesky! This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.allelitewrapup.com

On Episode 213 of The AEW-some Pod, the gang—Diana Prince, Johnny Taylor, and Gringo Fantastico—goes three-hours deep on AEW's UK Holiday Bash as Dynamite and Collision take over Manchester's Co-op Live. The gang breaks down The Elite's million-dollar win over the Don Callis Family (and how Okada might hate his own team more than The Bucks), Pac's hometown heater against Kyle Fletcher to blow the Gold League wide open, and Jon Moxley and Orange Cassidy grinding through Continental Classic wars with Roderick Strong and Mascara Dorada. They also dig into MJF's big return to crash the Worlds End contract signing with Joe, Hangman, and Swerve, Mercedes & Athena's march toward the Women's Tag Titles, Jamie Hayter's Collision homecoming and Sisters of Sin beatdown, plus FTR and the Bang Bang Gang delivering a sneaky tag-of-the-year candidate in the main event. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Support our sponsor this week by using the link below for the exclusive Solomonster offer!FACTOR MEALS ▶ Use code "solomonster50off" at http://www.factormeals.com/solomonster50off to get 50 PERCENT OFF your first box plus FREE BREAKFAST for one year!Solomonster reviews the Holiday Bash episode of AEW Dynamite/Collision ffrom Manchester, England with the return of MJF, cashing in his World title contract to insert himself into the Worlds End main event.  Plus, lots of Continental Classic matches, the first challengers for the Women's tag team titles become clear and WHO WINS THE MILLION DOLLARS!?!?!  Yay!***Follow Solomonster on X (formerly Twitter) for news and opinion:http://x.com/solomonsterSubscribe to the Solomonster Sounds Off on YouTube:https://www.youtube.com/user/TheSolomonster?sub_confirmation=1Become a Solomonster Sounds Off Channel Member:https://www.youtube.com/channel/UC9jcg7mk93fGNqWPMfl_Aig/join

W/ BALANCE AND COMPOSURE AND SOUL BLIND16/01 LONDON, UK @ O2 FORUM KENTISH TOWN17/01 MANCHESTER, UK @ O2 RITZ18/01 GLASGOW, UK @ SWG3 GALVANIZERS20/01 BRISTOL, UK @ O2 ACADEMY 22/01 DUBLIN, IE @ ACADEMYw/ Angel Du$tApr 25, 2026 Sick New World - Las VegasApr 30, 2026 The Triffid Brisbane, AustraliaMay 2, 2026 170 Russell Melbourne, AustraliaMay 3, 2026 Liberty Hall Sydney, AustraliaMay 5, 2026 Lion Arts Factory Adelaide, AustraliaMay 6, 2026 Amplifier Bar Perth, AustraliaJul 9, 2026 Two Thousand Trees Festival Cheltenham, EnglandOct 24, 2026Sick New World Texas Dallas, TX

The FC crew react to Manchester United's 4-4 draw vs Bournemouth and question why Ruben Amorim's side can't hold a lead. Plus, Dimitar Berbatov breaks down Mo Salah's return to the Liverpool squad and tries his best to explain what's going wrong at Tottenham. Mario Melchiot also reacts to Enzo Maresca refuses to expand upon his "worst 48 hours" remarks. Learn more about your ad choices. Visit podcastchoices.com/adchoices