Podcasts about bisphosphonates

Broadcast from KSQD, Santa Cruz on 5-15-2025: Dr. Dawn provides a comprehensive overview of bone health, describing bones as the "silent architects" of our bodies that require ongoing care and attention throughout life. She outlines key risk factors including family history of fractures, eating disorders, hormonal changes, digestive surgeries, and medication use, while explaining how DEXA scans measure bone density through T-scores and Z-scores, recommending the FRAX risk calculator as a superior predictive tool. She shares practical strategies like weight-bearing exercise and proper vitamin supplementation (D, K2, calcium) alongside explaining the roles of osteoclasts and osteoblasts in bone turnover and how medications influence this balance. She addresses a caller's question about strontium citrate and isoflavone supplements for bone health after cancer treatment, clarifying that these differ from problematic boron and suggesting C-telopeptide or N-telopeptide testing to verify bone turnover rates beyond DEXA results. The program discusses a promising non-hormonal male contraceptive called ADAM, a dissolvable hydrogel implant shown in preliminary trials to block sperm for up to two years without serious side effects. Dr. Dawn addresses misconceptions about autism, describing it as a spectrum with diverse manifestations, explaining its neurological basis in atypical brain pruning patterns, and emphasizing it as a complex genetic vulnerability to environmental events. She evaluates a listener email about a supplement for urinary incontinence and metabolic health, warning listeners about marketing tactics and insufficient evidence behind many commercial products. Dr. Dawn examines "Fatty 15," a pentadecanoic acid supplement marketed for metabolic health, noting that while some rodent studies show promise for insulin sensitivity and liver health, human evidence remains limited compared to well-established benefits of omega-3 fatty acids. Dr. Dawn shares news about Orforglipron, a new oral GLP-1 medication in pill form for diabetes and weight management that appears as effective as injectable versions like Ozempic.. The show concludes with information about innovative plant-based transparent paperboard, a cellulose-based material that biodegrades within 300 days while offering a safer and more sustainable alternative to conventional plastics.

Osteoporosis is a serious loss of healthy bone turnover.  Conventional medicine offerings focuses on bisphosphonate drugs which stops bone remodeling.  This looks good on a bone density test but retains poor quality bone.  Bisphosphonate drugs even interfere with cholesterol production just as statin drugs to. 

In this episode of the Better Than Before Breast Cancer podcast, we're diving into how common post-treatment medications—like Tamoxifen, Aromatase Inhibitors (Letrozole, Anastrozole, Exemestane), Herceptin, Fulvestrant, and Bisphosphonates (like Fosamax and Reclast)—can deplete critical nutrients your body needs to feel good and stay strong. Have you ever wondered if the medications you're taking after breast cancer treatment could be affecting your energy, mood, or even your bone health? You're not imagining things. You'll learn: Which nutrients are most commonly depleted by these medications (like magnesium, vitamin D, calcium, B12, and CoQ10) The symptoms that may be tied to nutrient deficiencies (think fatigue, brain fog, joint pain, and more) How some medications may increase cholesterol levels or raise your risk of fatty liver Why supporting your body with the right foods and lifestyle habits can make all the difference Plus, I'll share simple, whole-food nutrition strategies and daily lifestyle tips that can help you feel more energized, support your bones, balance your mood, and reduce long-term side effects—without adding overwhelm. Whether you're taking medications now or just want to be prepared, this episode is packed with practical, supportive guidance to help you stay nourished and in tune with your healing body.   Resources and Studies Mentioned: Tamoxifen and Metabolic Risks Aromatase Inhibitors and Bone Health Bisphosphonates and Bone Metabolism Fulvestrant and Bone Health Herceptin and CoQ10 Support Metformin and Vitamin B12 Deficiency   Subscribe, listen, and share to help other women embrace joy as their right and not just a reward.  

Why You Should Listen:  In this episode, you will learn about osteoporosis and how to fracture-proof your bones. About My Guest: My guest for this episode is Dr. John Neustadt.  John Neustadt, ND is the Founder and President of Nutritional Biochemistry, Inc. (NBI).  Dr. Neustadt earned his naturopathic medical degree from Bastyr University where he was awarded the Founder's Award for academic and clinical excellence.  Dr. Neustadt has published more than 100 medical articles, written four health and wellness books and is now a #1 Amazon Best Selling Author in the field of Osteoporosis.  His most recent book is Fracture-Proof Your Bones: A Comprehensive Guide to Osteoporosis.  Dr. Neustadt was also an editor of the textbook Laboratory Evaluations for Integrative and Functional Medicine, which was used across the United States to train and educate physicians on using functional medicine with their patients.  Key Takeaways: What are bones made of? What factors increase the risk of bone loss as we age? What is the difference between osteopenia and osteoporosis? What tests are the best for exploring bone health? Why are muscle strength and balance so important? What type of exercise is optimal for bone health? What are the benefits and risks of calcium? Does the parathyroid contribute to issues with bone health? What is the role of pharmaceutical medications in less than optimal bone health? What role do hormones play in osteoporosis? Is sleep important for bone health? Do nutritional deficiencies play a role in bone loss? What is the optimal bone health diet? What role does nitric oxide and circulation play in bone health? Is calcium taken from the bone to buffer acidosis? Is there a place for pharmaceutical medications in supporting bone health? What is the role of calcium, vitamin D, K2, and collagen in bone health? Can boron and strontium be supportive? Can bioDensity and OsteoStrong benefit those with bone loss? Is there a place for peptides, stem cells, or exosomes in supporting bone health? Connect With My Guest:  NBIHealth.com Interview Date: March 25, 2025 Transcript: To review a transcript of this show, visit https://BetterHealthGuy.com/Episode215. Additional Information: To learn more, visit https://BetterHealthGuy.com. Follow Me on Social Media: Facebook - https://facebook.com/betterhealthguy Instagram - https://instagram.com/betterhealthguy X - https://twitter.com/betterhealthguy TikTok - https://tiktok.com/@betterhealthguy Disclaimer:  The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority. 

Too busy to read the Lens? Listen to our weekly summary here! In this week's episode we discuss…Patching later in childhood for unilateral congenital cataract does not necessarily yield better final visual acuity. Intraoperative floppy iris syndrome was shown to be associated with use of certain antidepressants as well as inhalers, with some sex-specific patterns. Bisphosphonate use is linked to a higher cumulative incidence of age-related macular degeneration secondary to inflammatory signaling pathway activation. 

Drs. Singer and McClung discuss the operationalization of a bisphosphonate “drug holiday” in people treated with this class of osteoporosis medication. They address questions regarding patient selection criteria, duration of the holiday, and strategies for determining when and with what medication treatment should be resumed.

Broadcast from KSQD, Santa Cruz on 1-23-2025: Dr. Dawn announces a recall of Mylan's generic levothyroxine due to quality testing failures, affecting lots expiring in 2025 that don't meet FDA's 5% threshold for stated content. She provides comprehensive guidance on health impacts from the Moss Landing California battery fire, discussing cancer risks, heavy metal exposure, and detoxification methods including testing options and protective measures. The show explores promising research on bisphosphonate treatment for osteoporosis prevention, discussing a study showing one or two doses of Reclast could prevent fractures in post-menopausal women with normal bone density. Dr. Dawn examines innovative research on transplanting foot sole cells to improve prosthetic comfort for amputees, explaining how fibroblast transplantation could create more durable skin surfaces. She discusses alternative treatments for gallstones, particularly focusing on using ursodiol combined with lithotripsy as a potential surgery alternative for high-risk patients. The show addresses listener questions about knee injections for osteoarthritis, explaining cortisone's benefits and discussing vitamin supplementation including vitamins D3 and K2 for bone health. Dr. Dawn provides detailed information to a caller about ischial bursitis treatment, discussing injection techniques and cushioning options for managing tailbone area pain.

Surgeon Roundtable Panel livestream featuring 8 top surgeons as they come together to discuss their surgical approaches in limb lengthening surgery. This is a rare opportunity to educate yourself more on limb lengthening from different surgeons as they share insights, address patient concerns, and provide invaluable advice for anyone considering this life-changing surgery. ____________

Bei Osteoporose werden die Knochen porös und brechen leichter. Der Weltosteopo-rosetag am 20. Oktober soll das Bewusstsein für die Knochengesundheit stärken.

In Episode 80 of the Stronger Bones Lifestyle Podcast, host Debi Robinson talks with the Professor Paul Lee, an expert in regenerative medicine, combining expertise in sports medicine, orthopedics, and medical engineering for over 30 years. Professor Paul shares his comprehensive approach to bone health, integrating the principles of physics, chemistry, biology, and time.** For FULL show notes, please visit: https://debirobinson.com/episode80/ Professor Paul offers practical tips, like checking out how our shoes wear down to spot alignment issues and making simple posture adjustments to fend off musculoskeletal problems. He and Debi also chat about yoga and how everyday awareness can make a huge difference.They discuss Wolff's Law, explaining that bones need to be loaded with the right amount of force to build density, but we need to do it safely and with proper guidance as well as how gut health, managing stress and lifestyle are critical in maintaining or even reversing bone health.The episode also touches on new tech in bone health diagnosis, highlighting the REM scanner over the traditional DEXA scan and ends with a conversation about how lifestyle changes and understanding our genetic and physiological makeup can positively impact our bone health.Key  Takeaways:[2:54] Who is Professor Lee[4:35] His life and education as an orthopedic surgeon[5:28] Breaking down bone health[6:23] Physics and muscular skeletal movement[10:56] Chemistry and diet[12:37] Drugs and changing your chemistry[16:11] Biology and how you feel in terms of stress, sleep and environment plus what's in your DNA[17:43] Epigenetics[21:22] DEXA and REMS Scans[27:56] Time and timing[31:45] Is bone loss reversible[32:07] Age – physical vs chronological[34:50] Bisphosphonate[35:49] Loading bones[43:12] His book Regeneration by Design Where to Find Guest:WebsiteLinkedInHis book, Regeneration by Design** For FULL show notes, please visit: https://debirobinson.com/episode80/ Memorable Quotes:"Science is what we need to bring into the medical space." [5:08] - Professor Paul"Just being so aware of how are you standing walking moving sitting." [9:45] - Debi"We don't just think about regeneration.  Its regeneration and degeneration. Its what we call an equilibrium." [10:27] - Professor Paul"It doesn't really matter how old you are, you can still start." [33:09] - Professor Paul"You will only perform well if you're in the right environment." [33:59] - Professor Paul         "It's cheaper to get a new pair of shoes than to get a hip replacement. And its quicker too." [38:49] - Professor PaulTo learn more about me and to stay connected, click on the links below:Instagram: @debirobinsonwellnessWebsite: DebiRobinson.comHealthy Gut Healthy Bones Program

BoneCoach™ Osteoporosis & Osteopenia - Joining us today to explore OSTEOPOROSIS & ORAL HEALTH DECLINE is Bone Coach Kevin Ellis.=>> CLICK HERE TO SAVE 10% ON HEALTHY BONES CO. ANNATROL BONE SUPPORT =>>FREE Stronger Bones Masterclass (Gain Access Now!)=>>FREE 7-Day Osteoporosis Kickstart=>>Apply to join the Stronger Bones Solution Program w/ the BoneCoach™ Team***Topics Covered0:00 - The connection between osteoporosis, oral health decline, and aging0:16 - How weak bones and weak teeth are related0:51 - The impact of osteoporosis on oral health and tooth loss2:34 - Personal story of severe dental issues and bone loss4:26 - What Geranylgeraniol (GG) is, its importance for bone and oral health, especially for those on statins or bisphosphonates6:18 - Research on GG's benefits for overall health6:58 - Recommended GG dosage for optimal support7:43 - Introducing Annatrol Bone Support: A GG and Tocotrienol supplement8:26 - Clinical studies on tocotrienols' effects on bone health, cholesterol, and inflammation9:45 - How to get Annatrol Bone Support***Resources MentionedFind all resources mentioned and show notes @=>> https://bonecoach.com/osteoporosis-oral-health-decline-healthy-bones-co-annatrol ***What can you do to support your bone health and this podcast?1. Hit the “Subscribe” Button. 2. Leave a review. Thank you!

Osteoporose ist eine Erkrankung, die zunächst zu einem Rückgang der Knochendichte und Knochenstruktur führt. Mit zunehmendem Alter und abhängig vom Geschlecht, steigt in der Kombination dieser Kriterien und noch weiterer Risikofaktoren das Risiko für osteoporosebedingte Knochenbrüche an. In dieser Folge beschäftigen wir uns mit einer typischen osteoporosebedingten Fraktur, der Hüftfraktur. Dabei gehen wir noch etwas mehr auf die Ursachen, vor allem aber auf die Therapie und die Bedeutung für die weitere Betreuung ein.

Welcome back to Pharmacy Fun with Star! Today, we're exploring bisphosphonates, a class of drugs essential for bone health. Bisphosphonates help prevent bone loss by inhibiting osteoclasts, the cells that break down bone tissue. They are commonly used to treat conditions like osteoporosis and Paget's disease, ensuring stronger, healthier bones. Tune in to learn more about how these medications work and their impact on bone health!

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In this eye-opening episode of "The Food Code," we bust the biggest myth in bone health—calcium! Discover why calcium supplements aren't the magic solution for osteoporosis and what you should really be concerned about. We dive deep into the latest research on postmenopausal osteoporosis, the critical role of hormones, and the surprising truth about bone density and resiliency. Join us as we uncover effective strategies to protect your bones and improve your overall health. Don't miss out on these crucial insights that could change your approach to osteoporosis forever!***Tune in to learn:[00:01:10] - Debunking Red Meat and Cholesterol Myths[00:02:00] - Becca's Personal Story: Conversations on Calcium and Hormones[00:03:29] - The Importance of Hormone Replacement Therapy (HRT)[00:05:00] - Understanding Bone Density vs. Bone Resiliency[00:10:19] - Major Study by JAMA: Calcium and Vitamin D Ineffectiveness[00:11:00] - The Role of Estrogen and Progesterone in Bone Health[00:16:24] - Should You Be Concerned About Osteoporosis?[00:19:47] - Side Effects of Bisphosphonates vs. HRT[00:21:52] - Key Takeaways: Effective Interventions for Osteoporosis***Don't forget to rate, review, and subscribe to the podcast! Share this episode with friends who need to hear this important message.***Have a question you want us to answer live? ASK HERELooking for high quality, therapeutic grade supplements? If so, join our practitioner portal, Fullscript, and purchase quality supplements 15% off!Our favorite nontoxic skincare is FRE Skincare. Their breakthrough dual action formula that fights breakouts and the signs of aging with high impact natural ingredients. Use code LIZROMAN at checkout!Get a FREE Sample pack of LMNT! LMNT is a electrolyte drink mix that is formulated to help anyone with their electrolyte needs and is perfectly suited to folks following a keto, low-carb, or paleo diet AND it is soo tasty - great for flavoring water and helping you drink more!***CONNECT

Welcome back to another enlightening episode of The Hormone Prescription Podcast! This week, we dive deep into a topic that resonates with so many of us: bone health. We often think we're doing enough by following generic health programs, but what if those programs fall short when it comes to bone health? What if there's a better way to ensure stronger, healthier bones?

In this episode, we review the high-yield topic of⁠⁠ Bisphosphonates ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Basic Science section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Orthobullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on Social Media: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message

Doctors Lisa and Sara talk to Dr Saadat Ahmed, ST5 in Geriatrics for a deep dive into Osteoporosis. We cover what it is, why it matters, what the risks factors are, who and how to assess for it, and what to do with results from FRAX and DXA scans. After a discussion on lifestyle options to help improve bone health, we ask advice on counselling patients around the pros and cons of taking Bisphosphonates including his advice on talking about the rarer side effects. We talk through a case and ask advice on how to reassess bone health after these initial conversations, and medications might have been started, including when to consider drug holidays.   Lots of excellent CPD here we feel. Enjoy and please share with any interested clinicians/trainees as you see fit.   Useful resources:  Osteoporosis - Prevention of Fragility Fractures NICE CKS Guidelines (updated Apr 2023): https://cks.nice.org.uk/topics/osteoporosis-prevention-of-fragility-fractures/ FRAX Calculator UK (Link from National Osteoporosis Guideline Group UK: https://frax.shef.ac.uk/FRAX/tool.aspx?country=1 WHO Falls Management: https://www.who.int/news-room/fact-sheets/detail/falls National Osteoporosis Guideline Group UK: https://www.nogg.org.uk/full-guideline/section-4-intervention-thresholds-and-strategy https://www.nogg.org.uk/full-guideline/section-7-strategies-management-osteoporosis-and-fracture-risk SIGN Scottish Osteoporosis Guidelines (discussion of evidence for links between PPIs and Osteoporosis on page 27): https://www.sign.ac.uk/media/1812/sign-142-osteoporosis-v3.pdf Osteonecrosis of the Jaw relative risk discussed on page 37 of National Osteoporosis Guideline Group UK: https://www.nogg.org.uk/sites/nogg/download/NOGG-Guideline-2021-g.pdf Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus, Journal of Bone and Mineral Research. Khan A et al 2015: https://pubmed.ncbi.nlm.nih.gov/25414052/ Flow Chart for Oral Bisphosphonates long term treatment and monitoring NOGG Guidelines: Page 35: https://www.nogg.org.uk/sites/nogg/download/NOGG-Guideline-2021-g.pdf Rubin KH, Rothmann MJ, Holmberg T, et al. Effectiveness of a two-step population-based osteoporosis screening program using FRAX: the randomized Risk-stratified Osteoporosis Strategy Evaluation (ROSE) study. Osteoporosis Int 2018; 29(3): 567-78. https://pubmed.ncbi.nlm.nih.gov/29218381/ Merlijn T, Swart KM, van Schoor NM, et al. The Effect of a Screening and Treatment Program for the Prevention of Fractures in Older Women: A Randomized Pragmatic Trial. J Bone Miner Res 2019; 34(11): 1993-2000. https://pubmed.ncbi.nlm.nih.gov/31220365/ Merlijn T, Swart KMA, van der Horst HE, Netelenbos JC, Elders PJM. Fracture prevention by screening for high fracture risk: a systematic review and meta-analysis. Osteoporosis Int 2020; 31(2): 251-7. https://pubmed.ncbi.nlm.nih.gov/31838551/ _____ We really want to make these episodes relevant and helpful: if you have any questions or want any particular areas covered then contact us on Twitter @PCKBpodcast, or leave a comment on our quick anonymous survey here: https://pckb.org/feedback Email us at: primarycarepodcasts@gmail.com _____ This podcast has been made with the support of GP Excellence and Greater Manchester Integrated Care Board. Given that it is recorded with Greater Manchester clinicians, the information discussed may not be applicable elsewhere and it is important to consult local guidelines before making any treatment decisions.  The information presented is the personal opinion of the healthcare professional interviewed and might not be representative to all clinicians. It is based on their interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it's release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen. Dr Lisa Adams, Dr Sara MacDermott and their interviewees are not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast - it is the clinicians responsibility to appraise the information given and review local and national guidelines before making treatment decisions. Reliance on information provided in this podcast is solely at the listeners risk. The podcast is designed to be used by trained healthcare professionals for education only. We do not recommend these for patients or the general public and they are not to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

How long should you wait after a root canal before starting Orthodontics? Should we be scared of orthodontic movement in those taking bisphosphonates? How do you decide if diastemas should be closed restoratively or orthodontically? Dr Daniel Neves answers every one of the questions and several more sent in from the Protrusive Community These questions are the tricky case-specific ones we ponder about and crave guidelines for - straight talking Dr Neves makes it all tangible. https://youtu.be/ZufVChjEJk4 Watch PDP186 on Youtube Protrusive Dental Pearl: Retention is not a ‘one and done' process. It should be customised for the individual and maintained appropriately - including at every routine check up. Highlights of this Episode:04:40 Protrusive Dental Pearl05:53 Introduction to Dr Daniel Neves 12:16 Reducing the Risk of Relapse17:20 Anterior Diastema21:47 Temporary Anchorage Devices (TADs)26:20 Jaw Issues in Adults29:20 Root Resorption34:25 Recession Cases38:00 Timing of Orthodontics after Root Canal Treatment39:39 Bisphosphonates and Orthodontics40:16 Aligners around Implants42:22 Final Thoughts If you liked this episode, you will also like GDP Alignment vs Specialist Orthodontics [STRAIGHTPRIL] – PDP068

In this weeks episode we dive into a topic that is close to my heart after watching the pain and suffering my mum went through and the complications and difficulties she has had after falling in her bedroom one day and breaking her hip.   This experience of course led me deep into the research on osteoporosis and in todays video/podcast we cover  What osteoporosis is and what osteopenia is  How is it diagnosed  What drugs are used to to treat it - the good, the bad and the ugly of these What exercises you can do to stave off osteoporosis and reverse bone loss What nutrient deficiencies or diseases can lead to osteoporosis  What supplements can reverse and or slow bone loss The role of different hormones in osteopororsis  The role of nutrition in osteoporosis  What medications can cause osteoporosis  What lifestyle factors can lead to osteoporosis Who is more at risk for osteoporosis. General info on osteoporosis  Loss of Bone Mass Density Dexa Scan T-score  -1.0 to -2.5 is Osteopenia                     T-score  less than -2.5 is Osteoporosis Bone is 40-50% inorganic component (hydroxyapatite), 10-15% water and 35% organic component(protein).  90% of the organic component is collagen Type 1 and the remaining 10% non-collagenous proteins Osteoblasts-formation of bone, secrete alkaline phosphatase to create sites for calcium and phosphate deposition. Osteoclasts-bone resorption, secretes acid phosphatase which unfixes the calcium Osteocytes are osteoblasts which are responsible for homeostasis of oxygen and mineral levels. Function: Supports the body, protects the organs, produces blood cells, and stores minerals and fats. Collagen, the protein that gives bones a framework for strength and   flexibility Calcium-phosphate mineral complexes, that fill in the gaps between the collagen frame work, making bones hard and strong Living bone cells that remove and replace weakened sections of bone KoACT-Calcium collagen chelate Animal Study-8 weeks 4 groups No supplement KoACT-increased bone density by 3.5% 10x KoACT-increased bone strength by 10% Calcium and Collagen supplement increase bone strength by 1% Study 39 women 2 groups-12 months Post-menopausal women. 5 g of CC(calcium-collagen chelate) which contains 500 mg of elemental calcium and 200 IU Vitamin D 500 mg of calcium and 200 IU of Vitamin D The loss of whole body BMD in women taking CC was substantially lower than that of the control group at twelve months KoACT improves bone synthesis and reduces bone loss KoACT counteracts the natural process of bone loss in post-menopausal women KoACT improves bone mineral density KoACT improves bone mineral density better than calcium in post-menopausal women KoACT improves total body bone mineral density significantly better than calcium in just three months Biomarkers for bone formation were increased significantly with KoACT KoACT improves biomarkers for bone formation, better than calcium. KoACT improves bone strength significantly better than calcium in animals Peak bone mass is around 30 years old. Losing 2-3% a year thereafter. 20% of hip fracture patients will pass away within a year. 1 out of 3 post menopausal women will fracture a bone Osteoporosis drugs (Bisphosphonate) slows down osteoclast activity. Increase risk of jaw necrosis and atypical femoral fractures.  After 3 years of use the suggest a "Drug Holiday" Lifestyle: Lack of physical activity Excessive exercise Inflammation Smoking Alcohol Medication Family history Vitamin and nutrient deficiency Gluten Eliminate excess sugar, cigarette smoke and phosphoric acid-containing soda. Be sure your intake of calcium and magnesium is in the 700-1000 mg range of each daily. Other trace minerals, boron, manganese, chromium, copper, zinc, silicon...animal food Weight bearing activity Post-menopausal women make consider bioidentical hormone replacement. Mediterranean diet with increase protein intake. Vegetarian and vegan diets and risks of total and site-specific fractures increases significantly. Exercise: Weight bearing resistance exercise is best Vibration-10 minutes per day 2-3x per day (check with your medical professional first) Muscle-vibration 20-50 hz Exercise inhibits bone loss, frequency matters     clinical research links mentioned in this podcast  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308846/ https://pubmed.ncbi.nlm.nih.gov/9177517/ https://pubmed.ncbi.nlm.nih.gov/9431639/ https://www.ncbi.nlm.nih.gov/books/NBK499863/#:~:text=Wolff's%20Law%20states%20that%20bones,strengthening%20of%20the%20cortical%20layer. https://pubmed.ncbi.nlm.nih.gov/23702931/#:~:text=Menaquinone%2D4%20(MK%2D4,health%20in%20healthy%20postmenopausal%20women.   Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with:  Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen,  intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals  Nutristat Omega 3 to 6 status and more  Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the  challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa    Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission.  Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to  Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to  https://www.buymeacoffee.com/LisaT to donate $3   Lisa's Anti-Aging and Longevity Supplements  Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world.  This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.   Subscribe to our popular Youtube channel  with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube   Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge"  Check them all out at  https://shop.lisatamati.com/collections/books   Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here:    Use code "tamati" at checkout to get a 10% discount on any of their devices.   Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38   Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off     Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts.  To pushing the limits, Lisa and team

Thanks again for all the wonderful questions, Osteoporosis has been our most listened to playlist and videos on youtube. Today we will discuss what you can do now to prevent osteoporosis and if you are in your 50's and 60's like me, what you can do to gain bone health through supplementation, diet and exercise. It's never too late to make a better change. As we have been discussing Bisphosphonates for Osteoporosis are dangerous. The most serious side effect can be to lose all your teeth from osteonecrosis it can cause the bone to die. Originally bisphosphonates like Boniva, Reclast, Fosamax just to name a few work to keep the "old" bone around. This can have an appearance of more bone on a bone density test, however, it is deceiving. Listen today to learn options to protect your bones and mobility and we will build on Part I, II and III. Your Everyday Health Hacker is Liza Leal, M.D. and her patient co-host Mike Herzing of "Let's Talk Wheels" a nationally syndicated program. Together we discuss topics from emails from around the world to help educate, inspire and be the resource for the latest medical dental topics. Write to us via email at info@everydayhealthhacker or call us at  281-265-6565 Meridian Medical Dental Healthcare (Dr. Duncan Foulds) powered by Meridian Health Institute in Sugar Land, Texas. Stay Tuned, Like, Comment and Subscribe https://everydayhealthhacker.com

Die Schilddrüse ist ein kleines Organ mit einer großen Wirkung. Auch auf die Knochen. In unserer heutigen Folge haben wir Dr. Uli Deuss zu Gast, der sich als Endokrinologe, speziell mit Erkrankungen des Hormonhaushaltes auskennt. Mit ihm sprechen wir über die Funktion der Schilddrüse und die Folgen einer Über- und Unterfunktion auf den Knochenstoffwechsel.

In today's episode of Breast Cancer Conversations, we dive deep into oral health! Before undergoing cancer treatment, it is crucial for individuals to prioritize their dental health. This is because cancer treatments, such as chemotherapy, can have significant effects on oral health, specifically how bisphosphonates may lead to Osteonecrosis of the Jaw (ONJ). In this podcast episode, we discuss the importance of visiting a dentist and dental hygienist before starting cancer treatment to achieve optimal oral hygiene. Topics Covered in this Episode: Bisphosphonates and dental health.Dental health considerations before cancer treatment.Oral health during cancer treatment.Understanding dental and medical coverage.Bisphosphonate-induced osteonecrosis of the jaw.Dental complications with bisphosphonates.Osteonecrosis symptoms and diagnosis.Nerve treatment during surgery.+++++++++++++++++++++Attend a free virtual SurvivingBreastCancer.org event:https://www.survivingbreastcancer.org/events+++++++++++++++++++++SurvivingBreastCancer.org's  Mission: To empower those diagnosed with breast cancer and their families from day one and beyond. About SurvivingBreastCancer.org: SurvivingBreastCancer.org, Inc. (SBC) is a federally recognized 501(c)(3) non-profit virtual platform headquartered in Boston with a national and global reach. Through education, community, and resources, SurvivingBreastCancer.org supports women and men going through breast cancer. We provide a sanctuary of strength, compassion, and empowerment, where those diagnosed with cancer unite to share their stories, learn invaluable coping strategies to manage wellness and mental health, and find solace in the unbreakable bond that fuels hope, resilience, and the courage to conquer adversity.+++++++++++++++++++++Follow us on InstagramLaura and Will: https://www.instagram.com/laura_and_will/SurvivingBreastCancer.org: https://www.survivingbreastcancer.org/Support the show

Die aktuelle Folge richtet sich in erster Linie an Expertinnen und Experten, aber natürlich auch an Interessierte. In dieser Folge beschäftigen wir uns mit einer aktuellen Studie. In der Untersuchung hat man einen Vergleich der verschiedenen Wirkstoffe zur Behandlung der Osteoporose mit bestimmten wissenschaftlichen Methoden durchgeführt. Die Methodik und auch die Ergebnisse erläutern wir in dem Podcast. Und bewerten die Bedeutung der Publikation für unseren klinischen Alltag. Für alle, die sich selbst ein Bild von der Studie machen oder tiefer in das Thema einsteigen wollen, haben wir hier den Link zu der Veröffentlichung (Publikation Händel et al.).

Thank you for all the questions regarding osteoporosis, biphosphonates and protecting your teeth. In Part 6 of osteoporosis and biphosphonates we will discuss protecting your bones naturally and what you can do now to prevent osteoporosis. Mobility is life and we want to keep you moving with a beautiful intact smile. Biphosphonates for Osteoporosis are dangerous. The most serious side effect can be to loose all your teeth from osteonecrosis it can cause the bone to die. Originally biphosphonates like Boniva, Reclast, Fosamax just to name a few work to keep the "old" bone around. This can have an appearance of more bone on a bone density test, however, it is deceiving. Listen today to learn options to protect your bones and mobility and we will build on Part I learning prevention is key to healthy bones and a healthy smile. Keep a look out for part III and IV coming soon! Mobility is Life, so many patients share I hurt all over I must be getting old. No, it's inflammation and we need to halt the inflammation to better protect the one body we have. As a medical dental practice, we see new patients who were referred to us for teeth that are moving. While there can be multiple causes: infection, medication, poor hygiene, poor lifestyle and more we must educate that many medications prescribed by their doctor can be the cause. One being biphosphonates. Today we will discuss alternatives including weight bearing exercise, hormones and a medical dental approach to keep your bones healthy. Your Everyday Health Hacker is Liza Leal, M.D. and her patient co-host Mike Herzing of "Let's Talk Wheels" a nationally syndicated program. Together we discuss topics from emails from around the world to help educate, inspire and be the resource for the latest medical dental topics. Write to us via email at info@everydayhealthhacker or call us at  281-265-6565 Meridian Medical Dental Healthcare (Dr. Duncan Foulds) powered by Meridian Health Institute in Sugar Land, Texas.

Thanks again for all the wonderful questions, Osteoporosis has been our most listened to playlist and videos on youtube. Today we will discuss what you can do now to prevent osteoporosis and if you are in your 50's and 60's like me, what you can do to gain bone health through supplementation, diet and exercise. It's never too late to make a better change. As we have been discussing Bisphosphonates for Osteoporosis are dangerous. The most serious side effect can be to lose all your teeth from osteonecrosis it can cause the bone to die. Originally bisphosphonates like Boniva, Reclast, Fosamax just to name a few work to keep the "old" bone around. This can have an appearance of more bone on a bone density test, however, it is deceiving. Listen today to learn options to protect your bones and mobility and we will build on Part I, II and III.  Your Everyday Health Hacker is Liza Leal, M.D. and her patient co-host Mike Herzing of "Let's Talk Wheels" a nationally syndicated program. Together we discuss topics from emails from around the world to help educate, inspire and be the resource for the latest medical dental topics. Write to us via email at info@everydayhealthhacker or call us at  281-265-6565 Meridian Medical Dental Healthcare (Dr. Duncan Foulds) powered by Meridian Health Institute in Sugar Land, Texas. Stay Tuned, Like, Comment and Subscribe https://everydayhealthhacker.com

To find out more about how Dentistry works in England, Doctors Lisa and Sara talk to Greater Manchester Workforce Lead for Dentistry Mukhtar Ahmad. We cover how Dental Services are set up and funded in England and some current challenges. We move on to specific questions about how General Practice and Dentistry can help each other. Themes include; information sharing, Bisphosphonates, Chemotherapy, Radiotherapy and Diabetes.  You can use these podcasts as part of your CPD - we don't do certificates but they still count :) Useful resources:  BMA Advice and Support Patients presenting with dental problems (Sept 2020): https://www.bma.org.uk/advice-and-support/gp-practices/gp-service-provision/patients-presenting-with-dental-problems?fbclid=IwAR1-rLLfHumLXMZSXxnb8UF_4acvgbTTcPYmvSQHa8VX18fM0Yn-8fCBoAk Scottish Dental Resources for Professionals: https://www.scottishdental.org/professionals/ Scottish Dental Clinical Effectiveness Programme. Management of Dental Patients Taking Anticoagulants or Antiplatelet Drugs (March 2022): https://www.sdcep.org.uk/published-guidance/anticoagulants-and-antiplatelets/ NHS Choices: Find A Dentist: https://www.nhs.uk/service-search/find-a-dentist Baby Teeth Do Matter: https://babyteethdomatter.org/ ___ We really want to make these episodes relevant and helpful: if you have any questions or want any particular areas covered then contact us on Twitter @PCKBpodcast, or leave a comment on our quick anonymous survey here: https://pckb.org/feedback Email us at: primarycarepodcasts@gmail.com ___ This podcast has been made with the support of GP Excellence and Wigan CCG. Given that it is recorded with Greater Manchester clinicians, the information discussed may not be applicable elsewhere and it is important to consult local guidelines before making any treatment decisions.  The information presented is the personal opinion of the healthcare professional interviewed and might not be representative to all clinicians. It is based on their interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it's release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen. Dr Lisa Adams, Dr Sara MacDermott and their interviewees are not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast - it is the clinicians responsibility to appraise the information given and review local and national guidelines before making treatment decisions. Reliance on information provided in this podcast is solely at the listeners risk. The podcast is designed to be used by trained healthcare professionals for education only. We do not recommend these for patients or the general public and they are not to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

In this episode, Dr. Brian Nielsen, expert on bone physiology from Michigan State University, weighs in the use of Os Phos in young horses. In this wide ranging talk, we discuss many issues of young horse health, from building better bone and minds, to the importance of pain.  We even get into the nitty gritty of bone biology and osteoporosis in women.  

In this episode, we review the high-yield topic of ⁠⁠⁠Bisphosphonates⁠ ⁠⁠from the MSK section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message

This week we have special guest, Dr. Adam Spivak, to talk about the new study on doxycycline post-exposure prophylaxis for STIs. Dr. Spivak is an infectious disease expert and works in both an HIV clinic and a free PrEP clinic. I also review the latest COVID-19 anticoagulation trial and a paper looking at rates of fracture non-union in people who receive bisphosphonates. Check it out! Doxycycline Post-exposure Prophylaxis for STIsHigh dose prophylactic anticoagulation in COVID-19Bisphosphonate and Rates of Fracture Non-unions Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R

In Episode 12 diskutieren Dr. Leo Rasche und der Osteologe Dr. Lothar Seefried (Uniklinik Würzburg) über die häufig mit dem Multiplen Myelom einhergehende Knochenerkrankung. Erfahren Sie mehr darüber, wie die Löcher (Läsionen) in den Knochen kommen und mit welchen Therapien man dem Abbau entgegenwirken kann. Jetzt reinhören!MAT-DE-2301305 v1.0 04/2023

Recently the Endocrine Society published a new clinical practice guideline entitled, “Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline.” What exactly is hypercalcemia of malignancy? What are its symptoms? How is it treated? And what do the guidelines recommend? To help answer these questions, host Aaron Lohr talks with Ghada El-Hajj Fuleihan, MD, MPH, professor of medicine at the American University in Beirut in Lebanon. She is the chair of the Society working group that developed this guideline. For helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Recently the Endocrine Society published a new clinical practice guideline entitled, “Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline.” What exactly is hypercalcemia of malignancy? What are its symptoms? How is it treated? And what do the guidelines recommend? To help answer these questions, host Aaron Lohr talks with Ghada El-Hajj Fuleihan, MD, MPH, professor of medicine at the American University in Beirut in Lebanon. She is the chair of the Society working group that developed this guideline. Show notes are available at https://www.endocrine.org/podcast/enp68-hypercalcemia-of-malignancy — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Recently the Endocrine Society published a new clinical practice guideline entitled, “Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline.” What exactly is hypercalcemia of malignancy? What are its symptoms? How is it treated? And what do the guidelines recommend? To help answer these questions, host Aaron Lohr talks with Ghada El-Hajj Fuleihan, MD, MPH, professor of medicine at the American University in Beirut in Lebanon. She is the chair of the Society working group that developed this guideline. Show notes are available at https://www.endocrine.org/podcast/enp68-hypercalcemia-of-malignancy — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Dr. R. Keith McCormick is a chiropractic physician specializing in the management of patients with osteoporosis. He is the author of the whole body approach to osteoporosis and his recently released book – Great Bones: Taking Control of Your Osteoporosis. Sports have always played a vital part in Dr. McCormick's life. He is the former U.S. record holder for the most points scored in a pentathlon competition. Dr. McCormick continues to compete in triathlons of all distances and has completed six Ironman competitions, five of them after recovering from multiple osteoporosis-related fractures. In this interview, Dr. McCormick discusses the current osteoporosis medications in terms of safety and indications for use as part of a comprehensive treatment plan.   Links Dr. McCormick's website, where you can purchase his new book - https://www.osteonaturals.com More Natural Approaches to Osteoporosis and Bone Health Summit 2.0 - https://morebonehealth.byhealthmeans.com/?idev_id=22547   Timestamps [03:34] Where to get his book [07:46] Mediations and Classifications [12:52] Who Is or Isn't a Candidate - The Risk Factors [18:49] Bisphosphonates and Fracture Reduction [24:01] How to Balance Which Way You Should Go [35:19] The Problems with Prolia [42:32] Anabolic [52:54] Dr. McCormick's Story   DISCLAIMER – The information presented on this podcast should not be construed as medical advice. It is not intended to replace consultation with your physician or healthcare provider. The ideas shared on this podcast are the expressed opinions of the guests and do not always reflect those of Margie Bissinger and Happy Bones, Happy Life Podcast.

Osteoporosis may be a forgotten disease – common but rarely treated. The 2023 guidelines are not here. Join host, Geoff Wall, as he reviews the new treatment recommendations and how we can optimize pharmacotherapy for all persons with osteoporosis.The GameChangerOsteoporosis is common and routine screenings should be implemented. Bisphosphonates are still the drug of choice, but treatment for persons over 65 should be made on a case-by-case basis.Show Segments00:00 - Introduction00:25 - Background on Osteoporosis04:17 - How Guidelines Are Formed08:45 - Bisphosphonate Recommendation14:14 - Denosumab Recommendation16:40 - Anabolic Drugs20:40 - SERMs22:24 - The GameChanger: Recommendations Summary27:20 - Closing Remarks HostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthReferences and ResourcesPharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults: A Living Clinical Guideline From the American College of Physicians. FRAX Calculator Redeem your CPE hereCPE (Pharmacist) Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the epidemiology and diagnosis of osteoporosis2. Apply the treatment guidelines for osteoporosis to a specific patient0.05 CEU/0.5 HrUAN: 0107-0000-23-063-H01-PInitial release date: 01/06/2023Expiration date: 01/06/2024Additional CPE and CME details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Drs. Ariane Guthrie and Dawn Knudsen Gerber discuss reporting trends of bisphosphonate-associated atypical fractures relative to increasing awareness across medical and lay communities with TSCP podcast hosts DeLon Canterbury and Kelly Ulen.

  Vidcast:  https://youtu.be/5T2aHV2jLqQ   Loss of bone calcium and structural integrity is a scourge of aging that particularly affects women.  The common treatment stops bone dissolution with bisphosphonate drugs like Fosamax or Actonel.  The more direct approach is the stimulation of bone formation which usually requires repeated injections of parathyroid hormone.  Now endocrinologists at Harvard's Mass. General Hospital have identified a small molecule SK-124 that, when administered orally, has parathyroid hormone-like effects including raising blood levels of calcium and vitamin D leading to new bone formation.  SK-124 works in mice and will be developed into a drug for humans in collaboration with the Radius Health pharmaceutical company.   https://www.pnas.org/doi/10.1073/pnas.2214396119   #osteoporosis  #parathyroidhormone #bisphosphonates #osteoclasts  

This week, join Mark, Kate, Gary and Henry as they discuss 4 studies: mortality reduction from the treatment of osteoporosis, hypnosis for patients with IBS, COVID rebound syndrome, and low FODMAP diets in patients with IBS.

Osteoporosis is typically treated in America with Calcium and Bisphosphonate drugs, but do these interventions work?  Perhaps more importantly, are the safe? In this episode of Vitality Radio, Jared goes all in on what you need to know to protect your bones without the risks associated with typical treatments.  Come join the brand new Vitality Radio Listeners Community page on Facebook here!!Visit the podcast website here: VitalityRadio.comJust a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure or prevent any disease. The advice given is not intended to replace the advice of your medical professional.You can follow us at @vitalityradio on Instagram, Facebook, and Twitter. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. If you'd like to shop our visit please visit us at vitalitynutrition.com. Thank you!

Dr. Centor discusses the risk for fractures during bisphosphonate drug holidays with Dr. Kaleen Hayes.

In this episode, I'm breaking down bisphosphonates, a class of drugs often used in the treatment of osteoporosis. Learn more about osteoporosis here. Want to maximize your learning by reading this information, too? Check out the article and references here. A big thank-you to HCA Healthcare for sponsoring this episode. You can learn more about HCA's robust Nurse Residency Program here.     RATE, REVIEW AND FOLLOW! If this episode helped you, please take a moment to rate and review the show! This helps others find the podcast, which helps me help even more people :-) Click here, scroll to the bottom, then simply tap to rate with 5 stars and select, "write a review." I'd love to hear how the podcast has helped you! If you're not following yet, what are you waiting for? It takes just a quick moment and the episodes show up like magic every Thursday. And, when I release a bonus episode, those show up, too! You'll never miss a thing! In Apple Podcasts, just click on the three little dots in the upper right corner here. Know someone who would also love to study with me? Share the show or share specific episodes with your classmates...when we all work together, we all succeed! On Apple Podcasts, the SHARE link is in the same drop-down as the follow link. Spread the love! Thanks for studying with me! Nurse Mo

Der Klinisch Relevant Podcast liefert Ärztinnen und Ärzten sowie Angehörigen der Pflegeberufe und medizinischer Fachberufe wie Physiotherapie, Ergotherapie und Logopädie kostenlose und unabhängige medizinische Fortbildungsinhalte, die Du jederzeit und überall anhören kannst.

An interview with Dr. Andrea Eisen from Sunnybrook Odette Cancer Centre and Ontario Health in Toronto, Ontario, co-chair on “Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: ASCO-OH (CCO) Guideline Update.” This guideline updates recommendations for which patients with primary breast cancer should be treated with bone-modifying agents, and which bisphosphonates are optimal. Read the full guideline at www.asco.org/breast-cancer-guidelines.

My mom is an Asian woman in her 70s with osteoporosis.  She tried an oral bisphosphonate and had horrible esophagitis.  She said never again, though she eventually tried an IV bisphosphonate.  She had terrible flu-like symptoms.  She said never again.  But based on reports that symptoms are worse the first time, she tried the IV again the next year and fortunately experienced no symptoms.  (Story used with permission, thanks mom!).   I tell this story because these issues don't typically register as more than a nuisance for clinicians, who frequently don't understand why their older patient with osteoporosis is not taking a bisphosphonate.  But our patients are walking with their feet, and adherence to bisphosphonates for osteoporosis is poor and decreases with time. When we have a medication with up front harms and downstream benefits, it's critical that we consider the time to benefit, or how long it will take an individual to benefit from a test or treatment.  Think of the 10 years it takes to benefit from colon or breast cancer screening, which is designed to detect slow growing cancers.  For individuals with a life expectancy less than the time to benefit, the up front harms outweigh the downstream benefits.   In this context, we talked this week with James Deardorff and Sei Lee about their study of time to benefit of bisphosphonates for osteoporosis, published in JAMA IM. What they found somewhat surprised us: it's pretty short, about 1 year!   Which makes me feel better about urging my mom to get treatment.  Bisphosphonates are pretty darn effective, and act quickly. We also discuss discontinuing bispohsophantes, and if we can use the same logic we consider when starting them.   Toward the end we talk about the launch of ePrognosis' new Time to Benefit tool.  This tool provides a clinical recommendation for starting/stopping medications and cancer screening based on the prognosis of the patient in front of you.  See screenshot below.  You can either access it directly here.  I you use the Lee Schonberg prognostic index for community dwelling older adults you will be directed to the tool, and it will automatically place the life expectancy at the calculated prognostic estimate.   James and Sei requested a terrific song - Bad to the Bone - much better than the Hannah Montana Bone Dance song they threatened me with (maybe next time). Enjoy! -@alexSmithMD

Do you love your medical podcasts, but sometimes wish your favourite shows would just team up for the odd awesome episode??Your ears are definitely in the right place.Jon and Barney are joined by brilliant MDTea hosts Dr Iain Wilkinson and Dr Stephen Collins. Together they deliver a masterclass in many aspects of elderly care and we uncover the greatest medical literature in the world! (From the last few months).1) Physical Activity in Hopital patients - They do too little but you can help.2) Bisphosphonates meta-analysis - harm v benefit.3) Mirtazapine in  patients with dementia - should we use?4) Subsegmental PEs - who cares about them?5) Lifelong anticoagulation - hard decisions need these facts. 6) Athletes at higher risk of AF - sorry!7) POCUS- can it change outcomes?Subscribe / rate on Spotify / Apple. Follow us on Twitter / Instagram. Send us FEEDBACK JournalSpotting@gmail.com. Share with your pals/colleagues/random groups on WhatsApp. 

Question: Would you use bisphosphonate drugs to treat spaceflight related bone loss for long duration space missions? Follow us on twitter! https://twitter.com/TalkSpaceMed Join our discord! https://www.google.com/url?q=https%3A%2F%2Fdiscord.gg%2FWtUcKYyH3b&sa=D&sntz=1&usg=AFQjCNFWSYEMvPusokT0AL50JKsRt2cg8g Credit: Everyday Astronaut for intro music! (Listen here) https://www.youtube.com/watch?v=LQMq4YEMvH8&list=PL-ptSDHlAdQNZ4LxFv_c5MEsmQ6i8bQUN&pbjreload=101&ab_channel=EverydayAstronaut (Buy here) https://www.amazon.com/Maximum-Aerodynamic-Pressure-Everyday-Astronaut/dp/B07KPVRG67/ref=sr_1_1?dchild=1&keywords=maximum+aerodynamic+pressure&qid=1612331710&sr=8-1 References 1. Watts NB, Bilezikian JP, Camacho PM, et al. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis. Endocr Pract. 2010;16(Suppl 3):1-37. doi:10.4158/EP.16.S3.1 2. Sibonga JD. Spaceflight-induced bone loss: Is there an Osteoporosis Risk? Curr Osteoporos Rep. 2013;11(2):92-98. doi:10.1007/s11914-013-0136-5 3. Kennel KA, Drake MT. Adverse Effects of Bisphosphonates: Implications for Osteoporosis Management. Mayo Clin Proc. 2009;84(7):632-638. doi:10.1016/s0025-6196(11)60752-0 4. Program HR. Human Research Program Integrated Research Plan.; 2020. 5. Sibonga JD, Spector ER, Johnston SL, Tarver WJ, Reeves JM. Evaluating bone loss in ISS astronauts. Aerosp Med Hum Perform. 2015;86(12 Suppl):A38-A44. doi:10.3357/AMHP.EC06.2015 6. Blaber EA, Dvorochkin N, Lee C, et al. Microgravity Induces Pelvic Bone Loss through Osteoclastic Activity, Osteocytic Osteolysis, and Osteoblastic Cell Cycle Inhibition by CDKN1a/p21. PLoS One. 2013;8(4). doi:10.1371/journal.pone.0061372 7. Blaber EA, Dvorochkin N, Torres ML, et al. Mechanical unloading of bone in microgravity reduces mesenchymal and hematopoietic stem cell-mediated tissue regeneration. Stem Cell Res. 2014;13(2):181-201. doi:10.1016/j.scr.2014.05.005 8. McCarthy I, Goodship A, Herzog R, Oganov V, Stussi E, Vahlensieck M. Investigation of bone changes in microgravity during long and short duration space flight: Comparison of techniques. Eur J Clin Invest. 2000;30(12):1044-1054. doi:10.1046/j.1365-2362.2000.00719.x 9. Leblanc A, Schneider V, Shackelford L, et al. Bone Mineral and Lean Tissue Loss after Long Duration Space Flight. Vol 1.; 2000. 10. Collet P, Uebelhart D, Vico L, et al. Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans. Bone. 1997;20(6):547-551. doi:10.1016/S8756-3282(97)00052-5 11. Coulombe JC, Senwar B, Ferguson VL. Spaceflight-Induced Bone Tissue Changes that Affect Bone Quality and Increase Fracture Risk. Curr Osteoporos Rep. 2020;18(1). doi:10.1007/s11914-019-00540-y 12. LeBlanc A, Matsumoto T, Jones J, et al. Bisphosphonates as a supplement to exercise to protect bone during long-duration spaceflight. Osteoporos Int. 2013;24(7):2105-2114. doi:10.1007/s00198-012-2243-z 13. Mashiba T, Hirano T, Turner CH, Forwood MR, Johnston CC, Burr DB. Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res. 2000;15(4):613-620. doi:10.1359/jbmr.2000.15.4.613 14. Ammann P, Rizzoli R. Bone strength and its determinants. Osteoporos Int. 2003;14 Suppl 3. doi:10.1007/s00198-002-1345-4

In this episode I cover Paget's disease of the bone.If you want to follow along with written notes on Paget's disease of the bone go to https://zerotofinals.com/medicine/rheumatology/pagetsdisease/ or the rheumatology section in the Zero to Finals medicine book.This episode covers the definition, causes, investigations, diagnosis, management and complications of Paget's disease of the bone. The audio in the episode was expertly edited by Harry Watchman.