Podcasts about metabolic medicine

Revolutionizing Regenerative Medicine: The Power of Mass-Produced Mitochondria: Nutritionist Leyla Muedin explores groundbreaking research on stem cell-based methods to mass-produce human mitochondria, which could revolutionize regenerative and anti-aging medicine. She delves into the science and potential health benefits, discussing how increased mitochondrial production can improve conditions like osteoarthritis, heart disease, and neurodegenerative disorders. Leyla also provides practical advice on ways to enhance mitochondrial health through dietary and supplement strategies, offering listeners actionable steps to boost their health span and lifespan.

In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the human connections in metabolic medicine. With special guest Alisha, a nurse practitioner at the Cooper Center for Metabolism, the episode delves into how patient-provider relationships have a profound impact on metabolic health outcomes. If you're interested in how the world of metabolic medicine is evolving and want a human-centered perspective, this episode is a must-listen. You'll walk away with a better understanding of how interconnected our body's health systems are and why personalized care matters.Key Takeaways:Alisha's Journey: Discover how Alisha transitioned from the ICU to preventive care in metabolic medicine, driven by her desire to prevent end-stage diseases she witnessed firsthand.Breaking Myths: The episode sheds light on why counting calories isn't the answer and how metabolic dysfunction is not just a collection of isolated symptoms but a comprehensive system affecting overall health.Preventive Mindset: Learn from Dr. Cooper and Alisha as they discuss the importance of early intervention, preventive care, and how understanding your body's metabolic signals today can avert future health issues.Finding the Right Help: Looking for an expert in obesity medicine? Click the following link to find a board-certified specialist in your area: https://abom.learningbuilder.com/public/membersearchResources:Connect with Dr. Emily Cooper on LinkedIn.Connect with Mark Wright on LinkedIn.Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won't go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn't a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, send an email to emily@fatsciencepodcast.com.  If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

Today, I'm joined by Dr. Doug Lucas, a leading expert on osteoporosis, as we dive deep into innovative approaches for reversing this widespread bone disease. With over 50 million people in the U.S. affected by osteoporosis, understanding the causes and solutions is more crucial than ever. In this conversation, we explore how osteoporosis develops as a result of an imbalance in the body's metabolic processes, making bones more fragile and prone to fractures. Dr. Lucas shares his expertise on shifting away from traditional pharmacological treatments and embracing lifestyle and dietary changes. We discuss the power of hormone replacement therapy, the importance of personalized nutrition, and how comprehensive testing like REMS ultrasound and blood panels can uncover the root causes of bone loss. If you're looking to optimize your health span, identify the early signs of osteoporosis, and learn how to incorporate nutrition and exercise into your routine for better bone density, this episode is packed with essential insights. Tune in to uncover how small shifts in your daily habits can make a big impact on your bone health. Key Takeaways: Osteoporosis is fundamentally an imbalance of bone metabolism, which can be reversed naturally through lifestyle modifications and nutritional interventions. Hormone replacement therapy is a crucial consideration for maintaining bone health, especially in postmenopausal women. Personalized dietary plans focusing on adequate protein intake from animal sources are vital for preventing osteoporosis. Comprehensive testing, including REMS ultrasound and detailed blood panels, are essential for diagnosing and monitoring osteoporosis effectively. An integrative approach addressing diet, lifestyle, hormonal balance, and physical activity can significantly improve bone health and overall well-being. More About Dr. Doug Lucas: Dr. Doug Lucas is a double board-certified physician specializing in osteoporosis reversal, hormone replacement, and healthspan. After completing his training at Stanford University and practicing for nearly a decade in the field of orthopedic surgery, Dr. Doug left his practice to pursue an additional fellowship and board certification in anti-aging and regenerative medicine. He went on to achieve the status of fellow in Anti-Aging and Metabolic Medicine. This functional and hormone training gave him the breadth and depth of knowledge to support his deeply held philosophy of patient care and start Optimal Human Health MD (OHH), his nationwide telehealth practice. Dr. Doug has gone on to build a team of experts, each with a unique skill set, to help optimize his patients' health and help them live better, longer. The OHH team now focuses exclusively on bone health through the lens of optimization with a dual mission to educate the world that osteoporosis is reversible and to provide an unparalleled patient experience. Dr. Doug spends much of his professional time exploring, researching, and uncovering truths behind the controversies in bone health. His mission to educate the world plays out on his YouTube channel, The Dr. Doug Show: Bones, Hormones and HealthSpan, within his membership community, HealthSpan Nation, and on stages across the globe. His patients experience the direct benefit of his efforts and his dissemination of groundbreaking and paradigm-shifting research to his team. Dr. Doug also enjoys helping physicians find their own path to escape the traditional medical model and serve their patients in their own unique niche. Website Instagram Facebook Connect with me!: Website Instagram Facebook YouTube

New weight loss drugs known commercially as Wegovy and Mounjaro have been demonstrated to have a big effect in helping people to lose weight, and have recently been approved for use in obesity treatment in the NHS in England. In total, 4.1 million people would meet the criteria to be eligible to take one of these drugs. That seems fantastic - an end to obesity in our time. The problem is can we afford these drugs without bankrupting the NHS? How badly do we need them? But will this work? Should we be more ambitious? Can this help the NHS? Or bankrupt it? Guests: John Wilding, Professor of Medicine at The University of Liverpool. Alfie Slade is Government Affairs Lead at the Obesity Health Alliance Naveed Sattar, Professor of Metabolic Medicine at the University of Glasgow. Daniel Susskind, Research Professor in Economics at King's College, London. Dr Ellen Fallows, GP and Vice-President of The British Society of Lifestyle Medicine.Presenter: David Aaronovitch Producers: Charlotte McDonald, Kirsteen Knight and Beth Ashmead Latham Sound engineers: Rod Farquhar, Neva Missirian Editor: Richard Vadon Production Co-ordinator: Gemma Ashman

In this episode, Jonathan Sackier welcomes Martin Whyte to delve into the intricate world of metabolic medicine. Together, they discuss groundbreaking research on diabetes, non-alcoholic fatty liver disease, and polycystic ovarian syndrome, as well as how metabolic research is shaping the future of preventative care and treatment. Use the following timestamps to navigate this episode:  (00:00)-Introduction (02:10)-Journey into metabolic medicine (03:23)-Advances in Diabetes science (06:22)-Obesity and economic impact (08:28)-Patient terminology discussion (14:55)-Metabolic and chronic conditions (19:21)-Fatty liver disease (25:36)-Preventative health strategies (29:51)-Future of metabolic research (33:13)-Impact of GLP-1 drugs (37:08)-Fertility and menstrual disorders (41:01)-Thee wishes for healthcare

Today's episode is a refresher course or your introduction if you're new to Flipping 50 and not quite sure you can make the connection between sex hormones and bone density. Share this with younger women to understand “more than seen and felt symptoms” of perimenopause. Many women aren't aware of the options, pros and cons of hormone health. The more we know, the more we can make our own informed decisions. Bone density declines at menopause, and postmenopausal increases fracture risks. But do you know the importance of estrogen and testosterone in your bone health? Stay tuned to review the relationship between your sex hormones and bone density. My Guest: Dr. Doug Lucas is a double board-certified physician specializing in osteoporosis reversal and hormone replacement. After training at Stanford University, he transitioned from orthopedic surgery to anti-aging and regenerative medicine, gaining a fellowship in Anti-Aging and Metabolic Medicine and started Optimal Human Health MD (OHH) which is his nationwide telehealth practice. Dr. Doug educates the world through The Dr. Doug Show: Bones, Hormones and HealthSpan (YouTube), HealthSpan Nation and other platforms, while also mentoring physicians to prioritize patient-centered care. Questions We Answer in This Episode: What is the role of sex hormones in maintaining or improving bone density? [00:15:22] Can hormone replacement therapy (HRT) improve bone health? [00:18:32] What is the relationship between hormone decline and bone density? [00:14:17] What are the best strategies to maintain bone density with low hormone levels? [00:30:09] Connect with Dr. Doug: https://www.optimalhumanhealth.com/ On Social: Facebook: https://www.facebook.com/DrDougLucas/ YouTube: https://www.youtube.com/@Dr_DougLucas Instagram: https://www.instagram.com/dr_douglucas/ Other Episodes You Might Like: Bone Health, Osteoporosis, Osteopenia Tips You've Never Heard: https://www.flippingfifty.com/bone-coach/ Build Bone After Osteoporosis: https://www.flippingfifty.com/build-bone-after-osteoporosis/ Can I Still Start Hormones 10 Years After Menopause? Doctors Respond: https://www.flippingfifty.com/start-hormones-10-years-after-menopause/ Resources: Flipping 50 Membership: https://www.flippingfifty.com/cafe Flipping 50 STRONGER 12-week program: https://www.flippingfifty.com/getstronger

Welcome to today's podcast, where Pam and I are joined by Dr. Donese Worden. Dr. Worden is a world renowned expert in integrative healthcare. Her recent focus is on the metabolic treatment of cancer and neurologic diseases using hyperbaric oxygen therapy, specialized ketogenic diets and other natural approaches. She consults internationally and is personal physician to motivational speak, Les Brown. She's here to share her insights on the wellness industry, her innovative work in cancer care, and how naturopathy can work alongside conventional treatments for better outcomes. So whether you are someone with a chronic disease, a scary diagnosis, or you are just someone who wants to learn ways to stay healthy as you age, stay tuned as we dive into her unique approach to healing.

In this episode of UEG Talks, host Pradeep Mundre discusses the topic of weight loss drugs and their impact on obesity with Professor Carel Le Roux, Director of Metabolic Medicine at University College Dublin. They explore the historical perspective of obesity, the physiology of weight management, and the efficacy of different treatment modalities. They also discuss the future of weight loss management and the importance of treating obesity as a chronic disease.

We are joined by Dr. Ishna Sharma of St. Peter's Health Partners Bariatric and Metabolic Care. We'll discuss topics including robotic bariatric surgery, foregut surgery and the benefits and possible downsides of weight loss drugs. Ray Graf hosts.

I am thrilled to have Dr. Nick Norwitz, a researcher-educator on a mission to mainstream metabolic health, joining me today. Dr. Norwitz is a Dartmouth College graduate who completed his Ph.D in metabolism at Oxford University before attending Harvard Medical School to complete his MD.  Dr. Norwitz is passionate about teaching and encourages everyone to join the growing camp of metabolic health enthusiasts who will be instrumental in changing the world. In today's conversation, we explore the complex and controversial world of non-nutritive sweeteners, covering several topics, including the effects of allulose on PCOS, metabolic medicine, and the research on how gut sensor cells impact our preference for sugar over sweeteners. We look into studies on sucralose, commonly known as Splenda, and Dr. Norowitz shares insights from his Oreo LDL reduction experiment. We also touch on our human tendency toward simplicity and confirmation bias, the importance of bio-individuality, and the concept of N=1 medicine. Dr. Norwitz is committed to remaining curious. He will return to the podcast later this year to share more about the research on metabolic health, muscle, and metabolism. I know you will love this discussion, so stay tuned for more. IN THIS EPISODE YOU WILL LEARN: How the different molecules that exist within various types of non-nutritive sweeteners impact our biology Dr. Norwitz explains how his view on non-nutritive sweeteners has shifted over time. Why is allulose such a unique non-nutritive sweetener? How the brain can distinguish between different sweetener molecules, and why that can drive changes in behavior   Dr. Norwitz explains how the hypothesis that sucralose may cause insulin resistance, was proven incorrect. Why some non-nutritive sweeteners may be more problematic than others Dr. Norwitz shares his approach to creating engaging social media content and discusses his famous Oreo versus statin experiments. Why Dr. Norwitz believes that there should be more studies on lean mass hyper-responders How dietary changes affect LDL cholesterol levels What is N=1 medicine? Bio: Dr Nicholas Norwitz is a researcher-educator whose mission is to “Make Metabolic Health Mainstream.” He graduated Valedictorian from Dartmouth College, majoring in Cell Biology and Biochemistry. He then completed his PhD in Metabolism at the University of Oxford before attending Harvard Medical School to complete his MD.  Nick's enthusiasm for the field of Metabolism derives from a personal struggle with severe Inflammatory Bowel Disease. In desperation, he found a ketogenic diet put his disease into complete remission where conventional approaches failed. And he became curious… Fast forward, and Nick is now completing the last months of his dual doctorate, with a distinctive determination to upset the intellectual and social environment concerning metabolic health. His mantra is “Stay Curious,” he has a passion for teaching and wants to invite everyone to join the growing camp of Metabolic Health Enthusiasts who are going to change the world. Connect with Cynthia Thurlow   Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Nick Norwitz On YouTube Instagram X

We cover: Testosterone myths and truths When and if to take testosterone How testosterone is prescribed. Risks vs benefits DHEA vs testosterone cream How to really test for testosterone Injectables vs pellets vs creams Alternatives to testosterone therapy for bones, muscles and libido Prolactin, SHBG and albumin levels for testosterone Symptoms of testosterone insufficiency and overdose Dr. Doug Lucas is a double board certified physician. He completed his foundational training at Stanford University and then started a traditional orthopedic surgery practice in Durango, CO. But after just 5 years in this traditional medical model Dr. Doug decided he needed to get a second fellowship and board certification in Anti-Aging and Metabolic Medicine so that he can take a different approach to treating people's problems. And that's why he started Optimal Human Health MD (OHH).   His work led him to his expertise in metabolic health, hormone optimization and bone health.   He believes that osteoporosis is a disease that requires a comprehensive approach to Recognize WHY you are losing bone and then reversing those causes. Talk to Dr. Doug's team: https://www.optimalbonehealth.com/build-bone $500 off full service program Use code: ZORA ​​Kaatsu blood flow restriction bands https://kaatsu.com - use code ZORA for 5% off or contact me for orders outside USA. Research on bone health and kaatsu: https://drive.google.com/file/d/1-rweSP5N6Mr0G2igeScMye47jGMp_daV/view   EPISODES: Is Osteoporosis Reversible? - Dr. Doug Lucas Blood Flow Restriction with Steven Munatones Blood Flow Restriction with Dr. Chris Gaviglio Contact Dr. Doug Lucas: Instagram: @Dr_DougLucas  YouTube: The Dr. Doug Show: Bones, Hormones and Healthspan Facebook: @DrDougLucas  Website: https://www.optimalhumanhealth.com/ Healthspan nation membership group This episode is sponsored by Oxford Healthspan. The makers of my favorite spermidine supplement Primeadine. Use code ZORA for 15% off Primeadine spermidine ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Check out the ⁠⁠⁠⁠⁠⁠⁠⁠Menopause Method training⁠⁠⁠⁠⁠⁠⁠⁠ for doctors and medical professionals to learn how to prescribe hormone therapy for women in menopause. Go to the ⁠⁠⁠⁠⁠⁠⁠⁠Institute of Menopause Medicine⁠⁠⁠⁠⁠⁠⁠⁠'s website iobim.org to make an appointment to learn more and use the code ZORA for a discount. Download the ⁠⁠⁠⁠⁠⁠⁠⁠Hack My Age menopause programs⁠⁠⁠⁠⁠⁠⁠⁠ to optimize your menopause journey with evidence biohacks tailor made for a woman in perimenopause and menopause. Join the ⁠⁠⁠Biohacking Menopause⁠⁠⁠ community now for information and sharing you won't find anywhere else. This month's giveaway....win a bottle of Karen Martel's Hormone Facial Cream Estro2 Rejuvenate. Join before July 1, 2024 to enter into the draw.  If you missed the deadline, grab Karen Martel Hormones for 10% off with the code ZORA Join the Hack My Age community on: Facebook Page : ⁠⁠⁠⁠⁠@⁠Hack My Age⁠ Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠ Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠ Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠ ⁠Biohacking Menopause⁠ membership group Email: zora@hackmyage.com This podcast is edited by ⁠⁠⁠⁠⁠jonathanjk@gmail.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/hackmyage/message Support this podcast: https://podcasters.spotify.com/pod/show/hackmyage/support

Dr Fanny Mochel returns to the podcast to answer the question, "What can pediatricians learn from adult inherited metabolic diseases?" What can pediatricians learn from adult inherited metabolic diseases? Fanny Mochel https://doi.org/10.1002/jimd.12729

Today we have Dr. Nicholas Norwitz, 28, a third-year Harvard Medical School student whose research into the applications of a ketogenic diet as metabolic medicine has attracted a significant following. For a number of years during his youth, Nick suffered from a number of debilitating diseases, including osteoporosis, ulcerative colitis, and inflammatory bowel disease.  In today's interview, we talk to Nick about research that led him to adopt a ketogenic diet that put him back on the road to metabolic health. After graduating from Dartmouth College in 2018 with a degree in cellular and molecular biology, Nick attended Oxford University where he earned a Ph.D. in metabolism and nutrition. He is the author of peer-reviewed scientific papers and textbook chapters on topics including Alzheimer's disease, cardiovascular disease, diabetes, gastrointestinal health, genetics osteology and Parkinson's disease. Show notes:  [00:02:53] Marcas opens the interview mentioning that Neck grew up in Boston, and asks if it's true that he was a very curious kid growing up. [00:04:09] Marcas asks Nick if as a young child he always knew he wanted to be a physician and a scientist. [00:05:40] Ken mentions that Nick was a runner in high school, and as is the case with many runners, this led to fractures. However, Ken goes on to say that these fractures did not resolve for Nick, and asks what he learned as a result. [00:11:08] Ken asks about Nick's eating habits in college as he loved to cook and bake. [00:15:40] Marcas follows up, asking Nick at what point during his Ph.D. training was he admitted to palliative care. [00:21:01] Marcas pivots to talk about the need for incorporating metabolic health into our health-care system. He mentions that Nick once said that “we live in a society where our social norms and ecosystem, with respect to health and food, are extremely dysfunctional,” and asks Nick to elaborate on this. [00:26:16] Ken mentions a paper that Nick recently published titled, “Oreo Cookie Treatment Lowers LDL Cholesterol More Than High Intensity Statin Therapy in a Lean Mass Hyper-Responder on the Ketogenic Diet: A Curious Crossover Study.” To provide some background, Ken mentions that some people on a ketogenic or low carb diet experience a dramatic increase in LDL cholesterol. The rationale behind Nick's paper being that if it is the removal of carbohydrates that causes this increase in LDL, adding carbohydrates back into one's diet should bring LDL levels back down. Ken asks Nick to talk about this experiment and how he designed it. [00:35:44] Ken mentions that the paper seems to be designed to be provocative, as simply testing carbohydrates against statins would likely have not gotten as much attention as using Oreo cookies. [00:37:00] Marcas mentions that in the Oreo cookie vs statin experiment, Nick's original fasted-morning LDL was 384, before dropping it with Oreos, then doing a washout before dropping it again with statins. Marcas asks Nick what his fasted-morning LDL was post washout, prior to the statin intervention. [00:39:07] Marcas brings up Nick's paper titled: “The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate Restricted Diets.” Marcas goes on to mention that the aim of the paper was to propose a mechanistic explanation for the “lean mass hyper-responder phenotype.” Marcas asks Nick to give listeners an overview of the lipid-energy model. [00:45:18] Ken mentions that according to Nick, BMI is not a requirement for classification as a lean mass hyper-responder. Nick's paper, however, uses BMI data. Ken mentions that he finds BMI relatively useless and asks why Nick did not use DEXA scans instead. [00:48:52] Ken mentions that adipose tissue contains roughly 25 percent of total body cholesterol, and we know that LDL binding to adipose cell membranes is competitively inhibited by HDL. Ken asks if lean mass hyper-responders were found to hav...

In today's episode, we're talking about a disease so widespread that it touches nearly every family in some way: type 2 diabetes. It's not just a health issue, it's a rapidly expanding crisis. And many people don't know that they have it. In the U.S. alone, 100 million people have prediabetes, and more than 37 million have type 2 diabetes, a chronic condition with life-altering effects.Prof. Naveed Sattar joins us to shed light on preventing, treating, and potentially reversing type 2 diabetes. Naveed is a medical doctor and Professor of Metabolic Medicine at the Institute of Cardiovascular & Medical Sciences at the University of Glasgow. He's one of the world's top 1% most cited clinical scientists, and he's worked on many clinical trials of lifestyle changes and drugs to prevent and manage diabetes. Learn your diabetes risk score:If you're in the U.K. click here. If you're in the U.S. click here. Get the FREE ZOE gut health guide — download hereFollow ZOE on InstagramTimecodes:00:00 Introduction01:00 Topic introduction02:28 Quick fire questions05:33 What is blood sugar and why does it matter?07:15 What is insulin and what is its relation to blood sugar and diabetes?08:48 Why doesn't the body allow sugar to increase in the blood?10:45 What happens when somebody gets pre-diabetes or type 2?14:34 What is HBA1C?17:08 Why has there been such an increase in diabetes?23:05 How does muscle mass have any impact on diabetes?24:54 Are risks different between men and women?27:08 How does ethnicity come into this?31:04 What other personal risk factors are there?32:29 What are the symptoms of diabetes?33:53 When do these symptoms begin?35:09 What should you do if you have concerns?36:33 How to find out your own likelihood of risk38:34 How can we avoid getting diabetes?42:10 How can we combat genetic risk factors?44:26 Is it possible to lower blood sugar and reverse the effects of diabetes?47:18 What is the science behind the new drugs coming on the market?49:20 Summary53:39 OutroMentioned in today's episode: Primary care-led weight management for remission of type 2 diabetes (DiRECT): An open-label, cluster-randomised trial in The LancetIs there a nutrition topic you'd like us to explore? Email us at podcast@joinzoe.com, and we'll do our best to cover it.Episode transcripts are available here.

Melvyn Bragg and guests discuss some of the chemical signals coursing through our bodies throughout our lives, produced in separate areas and spreading via the bloodstream. We call these 'hormones' and we produce more than 80 of them of which the best known are arguably oestrogen, testosterone, adrenalin, insulin and cortisol. On the whole hormones operate without us being immediately conscious of them as their goal is homeostasis, maintaining the levels of everything in the body as required without us having to think about them first. Their actions are vital for our health and wellbeing and influence many different aspects of the way our bodies work.WithSadaf Farooqi Professor of Metabolism and Medicine at the University of CambridgeRebecca Reynolds Professor of Metabolic Medicine at the University of EdinburghAndAndrew Bicknell Associate Professor in the School of Biological Sciences at the University of ReadingProduced by Victoria BrignellReading list:Rachel Carson, Silent Spring (first published 1962; Penguin Classics, 2000)Stephen Nussey and Saffron Whitehead, Endocrinology: An Integrated Approach (BIOS Scientific Publishers; 2001)Aylinr Y. Yilmaz, Comprehensive Introduction to Endocrinology for Novices (Independently published, 2023)

Over the past 50 years, worldwide obesity rates have tripled, and now headlines increasingly shout of a public health crisis, even an obesity epidemic. Tom Sutcliffe explores the consequences of using such negative and emotional language to describe weight and the increasing rates of fat phobia in society. He looks at the health issues and the so-called ‘miracle drugs' that suppress appetite, and where genetics and diet meet. He's joined by Naveed Sattar, Professor of Metabolic Medicine at the University of Glasgow and recently appointed as the UK Government's Obesity Mission Chair, the body-positive activist Stephanie Yeboah who's the author of Fattily Ever After, and the businessman Henry Dimbleby whose book Ravenous reveals the mechanisms behind our food systems.Producer: Katy Hickman

Dr. Mark Houston is a thinker and researcher into the root causes of cardiovascular disease and metabolism. He graduated from Rhodes College in Memphis, Tennessee summa cum laude in Chemistry before graduating with honors from Vanderbilt Medical School. He completed his medical internship and residency at the University of California, San Francisco, then returned to Vanderbilt Medical Center where he was chief resident in medicine and served on the full- time faculty until 2012. He is the current director of the hypertension Institute where he and his team develop novel approaches to hypertension and ASCVD by attending to root biological causes of disease. He also has a Master's degree in Human Nutrition from the University of Bridgeport, Connecticut, and a Masters of Science degree in Functional and Metabolic Medicine from the University of South Florida in Tampa Florida. He has written hundreds of papers, books and chapters on cardiovascular disease. He is one of the top researchers in the preventative cardiology space and he is here today to share his wisdom. His book credits: Handbook of Antihypertensive Therapy Vascular Biology for the Clinician What Your Doctor May Not Tell You About Hypertension Hypertension Handbook for Students and Clinicians The Hypertension Handbook What Your Doctor May Not Tell You About Heart Disease. Please enjoy my conversation with Dr. Mark Houston, Dr. M Hypertension Institute

Dr. Mark Houston, Internist, and hypertension and cardiovascular specialist, is the cofounder of The Hypertension Institute, which immediately received national acclaim as one of the leading Institutes in the US for the treatment of hypertension and related cardiovascular disorders. Dr. Houston has presented over 10,000 lectures, nationally and internationally, and published over 250 medical articles, and scientific abstracts in peer-reviewed medical journals, books, and book chapters. He is an author, teacher, clinician, and researcher and is triple-boarded in hypertension as an American Society of Hypertension (ASH) specialist and Fellow of the American Society of Hypertension (FASH), Internal Medicine (ABIM), and Anti-aging Medicine (ABAARM). He also has a Master's degree in Human Nutrition from the University of Bridgeport, Connecticut, and a Master of Science degree in Functional and Metabolic Medicine from the University of South Florida in Tampa. Together Dr. Houston and I discuss a functional medicine approach to hypertension, including supplements, diagnosis, endophilia glycocalyx, and more. He shares hypertension statistics, why high blood pressure is so prevalent in the US, and the consequences of high blood pressure that physicians need to share with their patients. He offers insights into clinical trials and results of key blood pressure testing, the nutrients, dietary supplements, and lifestyle changes that can better support endophilia dysfunction, and key diet and lifestyle recommendations for hypertension including meat, fish oil, and sodium chloride intake. As Dr. Houston notes, hypertension can be impacted by both genetics and environment, and our conversation is filled with clinical pearls for physicians to share with their patients today for healthier blood pressure tomorrow. I'm your host, Evelyne Lambrecht, thank you for designing a well world with us. Key Takeaways: [2:45] Dr. Houston shares the family history that started his journey into integrative medicine. [4:32] Hypertension statistics, why it is so prevalent in the US, and the consequences of high blood pressure that physicians need to share with their patients. [7:06] Correctly diagnosing hypertension starts with properly testing blood pressure in the office and prescribing the correct medication to be taken at the right time of day. [12:03] Key concerns with medicines that result in low blood pressure and appropriate testing options. [15:57] The pathophysiology of hypertension as it relates to the arteries and endophilia glycocalyx. [18:32] Nutrients, dietary supplements, and lifestyle changes that can better support endophilia dysfunction to enhance nitrous oxide production and viability. [20:23] Dr. Houston highlights the clinical trials and results of key blood pressure testing. [24:17] Blood pressure medications and common nutrients that can be helpful for reducing blood pressure. [28:47] The relationships between nitric oxide production and the endothelial lining. [31:02] Physical improvements that accompany increased nitric oxide production and its potential impact on low blood pressure. [33:05] Dr. Houston's diet and lifestyle recommendations for hypertension including meat, fish oil, and sodium chloride intake. [38:38] The impact of genetics, stress, and exercise on hypertension. [44:10] The connection between the oral microbiome and blood pressure and cardiovascular health. [46:36] The relationship between iron and cardiovascular health. [49:03] Dr. Houston shares what he is most excited about in the future of the field of integrative and functional cardiology. [52:14] Dr. Houston highlights the greatest change he made over the course of his career, his three personal favorite supplements, and his preferred health practices.   Episode Resources: Dr. Mark Houston Design for Health Resources: Designs for Health Blog: Exploring the Dual Pathways and Nutrients for Enhanced Nitric Oxide Production Blog: The Intelligent Inner Lining of Blood Vessels: Nutrients that Support Vascular Health Nutrition Notes: The Intelligent Inner Lining of Blood Vessels: Nutrients that Support Vascular Health Webinar: The Supplement Toolbox - Research on Glycocalyx Regeneration and Nitric Oxide Webinar: The Role of the Endothelial Glycocalyx in Cardiovascular Disease Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

Stacy Marie is a double board certified Family and Acute care Nurse Practitioner with a passion for functional medicine & metabolic health.   She has a gift for making intricate health promotion & disease prevention interventions simple, accessible & manageable.   She's determined to help fill in the gaps where traditional medicine lacks by blending both conventional and functional medicine approaches.   Her mission is to empower you with the knowledge needed to understand your body, how to care and advocate for it, so you feel less stressed, less confused and happier in your own body.   Background/EDU:  FNP-BC, AGACNP-BC from University of South Alabama Masters of Nursing from UCLA  Bachelors of Science in Health Promotion and Disease Prevention from Cal State Fullerton  IFMCP- candidate  FAAMM candidate (Fellowship in Anti-aging and Metabolic Medicine) through A4M    Learn more about working with me  Shop my masterclasses (learn more in 60-90 minutes than years of dr appointments for just $19.99) Follow me on IG Learn more about working with Stacy Follow Stacy on IG   

Have you done a bone density test yet? If not, you will want to hear what my guest today, Dr. Doug Lucas says about that and osteoporosis. We discuss why women going through menopause need to be more attentive to this problem and what we can do to prevent or maybe even reverse it. If it's not too late. Dr. Lucas is a double board certified physician He did his foundational training at Stanford University and then started a traditional orthopedic surgery practice in Durango, CO. But after just 5 years in this traditional medical model Dr. Doug decided he needed to get a second fellowship and board certification in Anti-Aging and Metabolic Medicine so that he can take a different approach to treating people's problems. And that's why he started Optimal Human Health MD (OHH). His work led him to his expertise in metabolic health, hormone optimization and bone health, because so many women were having problems in this area. So he gathered his knowledge alongside experts to create the Optimal Bone Health MD, which is a sister company that shares resources focusing exclusively on bone health.   He believes that osteoporosis is a disease that requires a comprehensive approach to recognize WHY you are losing bone and then reversing those causes. $500 off the full service program with discount code: ZORA Contact Dr. Doug Lucas Website: www.optimalbonehealth.com Talk to Dr. Lucas' team: https://www.optimalbonehealth.com/build-bone Instagram: http://Instagram.com/Dr_DougLucas YouTube: http://youtube.com/@OptimalBoneHealthwithDrDougLucas Youtube: https://www.youtube.com/channel/UCwdGGy-YA3p28mYbfh19xqA Facebook: https://www.facebook.com/DrDougLucas/ OHH Website: https://www.optimalhumanhealth.com/ OBH Website: https://www.optimalbonehealth.com/ Join the Hack My Age community on: Facebook Page : ⁠⁠⁠http://facebook.com/hackmyage⁠⁠⁠ Facebook Group: Biohacking Menopause https://www.facebook.com/groups/biohackingwomen50 Instagram: ⁠⁠⁠http://instagram.com/hackmyage⁠⁠⁠ Website: ⁠⁠⁠http://www.hackmyage.com⁠⁠⁠ Hack My Age VIP Group: ⁠⁠⁠http://patreon.com/hackmyage⁠⁠⁠ Email: zora@hackmyage.com Newsletter: ⁠⁠⁠http://www.hackmyage.com/newsletter⁠⁠⁠ This podcast is edited by ⁠⁠⁠jonathanjk.com⁠ --- Send in a voice message: https://podcasters.spotify.com/pod/show/hackmyage/message Support this podcast: https://podcasters.spotify.com/pod/show/hackmyage/support

Laurie Pinkerton is a Certified Physician Assistant who helps her patients discover true health through knowledge and lifestyle interventions. As a compassionate Physician Assistant offering virtual medical/telemedicine care at The Karlfeldt Center in Boise, Idaho, she is dedicated to empowering patients through dietary and lifestyle interventions alongside integrative and traditional medicine approaches. Laurie is also trained in metabolic medicine, which means that alongside her daily assessment and evaluation of patient history, concerns, and medications, she can also discuss the role of medication reduction, smart eating, and lifestyle change in prevention and reversal of metabolic disease with patients and their families. Born and raised in Northern Virginia, Laurie came to Idaho to ski and learn about nutrition and organic farming by volunteering at small organic farms in Teton Valley.  Laurie graduated in 2020 from the Physician Assistant Program at Drexel University in Philadelphia. She is excited to help redefine medicine by offering lifestyle and holistic medical care through monthly programs with central focus on optimizing metabolism, hormones and health! She is currently practicing at The Karlfeldt Center,  where she started incorporating integrative and alternative therapies into her practice alongside standard of care.Find Laurie at-lauriepod1@gmail.comhttps://www.thekarlfeldtcenter.com/Schedule a FREE 15 minute discovery call at 208-338-8907Find Boundless Body at- myboundlessbody.com Book a session with us here!

Andrew Heyman, MD, MHSA is an internationally recognized expert in Integrative Medicine. He is currently the Program Director of Integrative and Metabolic Medicine at The George Washington University. Prior to assuming this role, he spent 16 years at the University of Michigan, serving to build one of the largest and most successful academic-based Integrative Medicine programs in the United States.   In 1990, he received formal training in Five-element Shiatsu and Traditional Chinese Medicine, during which time he developed an interest in increasing access of natural therapies to underserved populations while partnering with the University of Pennsylvania. He continued this work with Jim Gordon, MD at the Center for Mind-Body Medicine in Washington DC exploring the intersection between public health, at risk groups, and alternative therapies.   Dr. Heyman eventually went on to receive a Masters in Health Services Administration at the University of Michigan School of Public Health and upon graduation, became the administrator for the University of Michigan Complementary and Alternative Medicine Research Center where he was responsible for administering a $7 million NIH grant to research alternative therapies for cardiovascular diseases. The center was one of the first in the country to place alternative therapies and their scientific examination in an academic context.   Dr. Heyman has held several leadership positions in the field of Integrative Medicine. He was the national clinical working group co-chair of the Consortium of Academic Health Centers for Integrative Medicine for 4 years, a collaboration of 57 North American universities involved in Integrative Medicine. He is the online editor for the Journal of Men's Health in the section of Integrative Medicine, and he also holds the position of Editor-In-Chief of the Internet Journal of Anti-Aging and Aesthetic Medicine. His research interests include the Stress response and NeuroEndocrinology, Cardiometabolic Disease, Men's Health and clinical outcomes research methodologies.   Dr. Heyman remains clinically active as well, as the owner of a four-physician integrative medicine practice in Northern Virginia at the Virginia Center for Health and Wellness. He is also the President of Integrative Health Resources, a small group of clinical experts that consults to physicians, health systems and public health professionals seeking to develop wellness, lifestyle and nutrition programs.   Finally, Dr. Heyman has been featured on the Discovery Channel, Martha Stewart Living Magazine, Ladies Home Journal, Natural Health Magazine and appeared in many other TV and print venues and is a widely sought after, and celebrated speaker around the world on many Integrative Medicine topics. His teaching approach is described as deeply rooted in scientific evidence, grounded in the clinical reality of expert patient care, and readily accessible to both the new learner and seasoned practitioner alike.

Today's episode is dedicated to addressing a controversial topic - compound pharmacies and GLP-1 medications. The lack of availability and affordability of medications like Ozempic, Wegovy, and Mounjaro has become a growing concern. In light of this, The Plus SideZ has invited specialists to educate the community on compounding pharmacies. There is not enough information available on this topic, and our community is in dire need of guidance. Join us as we speak with Dr. Daniel Rosen, Dr. Myra Ahmad, and Dr. Adam Ripley to explore the ins and outs of GLP-1 compounding pharmacies. Our doctors have provided answers to some common questions regarding compound GLP-1 medications. They have addressed concerns about the safety of these medications and whether compound pharmacies are regulated. They have also explained that not all compound pharmacies are created equal and have highlighted some red flags that patients should look out for. Additionally, our doctors have addressed concerns about where compound pharmacies are sourcing drugs like Semaglutide or Tirzepatide, especially since retail brand manufacturers like Eli Lilly and Novo Nordisk have stated that they are not providing these medications to them.Bios of our doctor guests Dr. Daniel Rosenhttps://www.weightzen.com/dr-daniel-j-rosen/Daniel J. Rosen, MD – Dr. Rosen is a NYC bariatric surgeon. He specializes in the Lap-Band, Gastric Sleeve, Gastric Bypass, the Orbera Weight Loss Balloon, and Duodenal Switch. Dr. Rosen's bariatric practice is based on the Upper East Side, serving the greater New York area including Brooklyn, Northern New Jersey, Long Island, and Manhattan.As a general surgeon, he regularly performs laparoscopic minimally invasive abdominal procedures such as hernia repairs, gallbladder removals, and anti-reflux surgery.He received his medical degree from Albert Einstein College of Medicine, trained in general surgery at St. Luke's – Roosevelt Hospital Center, and completed fellowship training at New York Presbyterian Hospital. He has a dual fellowship in both bariatric surgery and laparoscopic surgery. Dr. Daniel Rosen was born in Brooklyn and completed his undergraduate degree from Cornell University.Dr. Daniel Rosen is certified by the American Board of Surgery and is a member of the American Society of Metabolic and Bariatric Surgery (ASMBS), and the Society of American Gastrointestinal Endoscopic Surgeons (SAGES).  His research has been published in leading surgical journals and is the recipient of multiple awards and recognitions.Dr. Myra Ahmadhttps://www.joinmochi.com/about-usCo-Founder & CEOThe University of Washington,School of MedicineUCSF Medical CenterDr. Adam Ripley, PharmD, RPhDirector of Pharmacy OperationsAequita PharmacyDr. Adam Ripley received his PharmD from the University of North Carolina -Chapel Hill Escheilman School of Pharmacy in 2000.  He completed his Fellowship in Functional and Metabolic Medicine through A4M in 2022. His 20-plus years of experience in multiple aspects of pharmacy practice include advanced specialty training in sterile and non-sterile compounding, pharmacy ownership, community practice, and consultation pharmacy practice.Support the showKim Carlos @DMFKimonMounjaro on TikTokJernine Trott @TheeJernine on TikTokKat Carter @KatCarter7 on TikTokLydia Roberts @mounjaro_GLP_Help on TikTok

With Antonio Cannata, BHF Centre of Excellence, School of Cardiovascular and Metabolic Medicine and Science. Faculty of Life Science and Medicine, King's College London, London - UK & Mauro Giacca, King's College, BHF Centre of Excellence, School of Cardiovascular and Metabolic Medicine and Science. Faculty of Life Science and Medicine, King's College London, London - UK. In this episode, Dr Cannata interviews Prof Giacca on the present and future perspectives of translational science in Heart Failure. A deep dive into the translational world with a view on the research of the next 30 years. 

In this episode, Dr. Brian interviews Dr. Nicholas Norwitz, who shares his fascinating journey with a low-carb ketogenic-style diet and its impact on his health. Dr. Nicholas, a Ph.D. holder from Oxford University and an incoming medical student at Harvard, talks about his personal health experiences and how they inspired him to start helping others. He also explains how his research has revealed the benefits of a low-carb diet and discusses some nutrition myths. This insightful conversation is a must-listen for those interested in exploring the connection between diet and health.Metabolic Medicine Is KeyMetabolic medicine is critical to understanding and preventing metabolic diseases. Metabolic diseases affect the body's ability to process and use energy. Examples include diabetes, obesity, cardiovascular disease, and osteoporosis. Metabolic medicine is an emerging field focusing on the underlying causes of metabolic diseases, such as insulin resistance, vitamin deficiencies, and hormone imbalances. By understanding the root causes of metabolic diseases, doctors can develop effective treatment plans to prevent and manage them.One of the most critical aspects of metabolic medicine is understanding how lifestyle and genetics can interact to cause metabolic diseases. For example, a person's diet, activity level, and genetics can all play a role in their risk of developing metabolic diseases. By understanding the connections between lifestyle and genetics, doctors can develop personalized treatment plans to address each individual's unique needs.How Can You Prevent Metabolic Diseases?In addition to understanding the underlying causes of metabolic diseases, metabolic medicine also focuses on prevention. By eating a balanced diet, exercising regularly, and getting enough rest, we can reduce our risk of chronic diseases and live a healthier, happier life. Additionally, if we are suffering from metabolic diseases, it is vital to seek professional help. Doctors can help us develop personalized treatment plans to address our individual needs.Finally, it is essential to be aware of the influence of big sugar on metabolic medicine. Companies like Coca-Cola and Pepsi have been known to fund research and education to influence what dietitians learn and how they disseminate information. This can lead to the promotion of unhealthy diets and the perpetuation of metabolic diseases. Overall, it is essential to address metabolic health for prevention. By understanding the underlying causes of metabolic diseases and taking steps to prevent them, we can reduce our risk of many chronic diseases and live a healthier, happier life. Metabolic medicine is vital to understanding and preventing metabolic diseases, and it is crucial to be aware of the influence of big sugar on the field.Industry Influences Nutrition GuidelinesNutrition guidelines are often biased by industry. The industry significantly influences nutrition guidelines and how we view food. Companies like General Mills fund continuing education courses to promote the idea that packaged foods are just part of life and can benefit our health. This idea of "everything in moderation" is often used to excuse people from indulging in unhealthy foods, even though many are engineered to be addictive. For example, when looking up the nutritional information for dates, it was discovered that 340 grams of sugar were needed to get the recommended amount of potassium, the richest nutrient in dates. This is a tremendous amount of sugar, and it is not an accurate representation of the health benefits of dates.In addition, many nutrition labels on ultra-processed foods are misleading and do not accurately reflect the nutrients available to our bodies. The word "fortified" is often used to make these foods seem healthier, but this Support the show

Click here to access our new membership portal and the FREE 5 hour mini -series OUTSMART OBESITY, HEART DISEASE & CANCER EVENTSClick here to get the OUTSMART BOOKClick here to get the OUTSMART HEALTH LABClick here to get the OUTSMART CLASSROOMClick here if you are a teacherClick here if you are a Cardiology practice or allied health professionalClick here to learn about Shane.In today's episode, I have a phenomenal treat that I've never done before. You are going to meet Professor Alta Schutte. In addition to this, you were going to get access to the full video episode with animation overlay describing what Dr Schutte and I talk about in the interview.Here is the background of todays' guest. Alta (Aletta E.) Schutte PhD FESC FRRSAf ISHF is SHARP Professor and Principal Theme Lead of Cardiac, Vascular and Metabolic Medicine in the Faculty of Medicine and Health at UNSW Sydney, Australia; with a joint appointment as Professorial Fellow at the George Institute for Global Health. She is a NHMRC Investigator Grant Leadership Fellow.She has extensive experience in working in clinical and population-based studies with a focus on raised blood pressure, hypertension and cardiovascular disease. She has been the Chief Investigator of several multidisciplinary studies, published >400 papers in the field of blood pressure and cardiovascular disease, and supervised over 85 postgraduate students. She is involved in numerous international consortia, such as the Global Burden of Disease study (Washington DC), the NCD Risk Factor Collaboration (London), May Measurement Month initiative of the International Society of Hypertension, and was one of 20 invited authors to join the Lancet Commission of Hypertension. She is the senior author of the 2020 International Society of Hypertension Global Hypertension Guidelines.She has been acknowledged for her work as winner of the Distinguished Woman Scientist in the Natural, Engineering and Life Sciences award, presented by the South African Department of Science and Technology; the NSTF South 32 TW Kambule Award; the British Association Medal from the Southern Africa Association for the Advancement of Science, the Meiring Naude Medal from the Royal Society of South Africa, the AU-TWAS (African Union & The World Academy of Sciences) Award, the 2019 African Union Kwame Nkrumah Regional Award for Scientific Excellence, 2020 KIFRA Prize in Science and 2022 Harriet Dustan Award of the American Heart Association's Hypertension Council.She serves as Associate Editor of Hypertension and the European Journal of Preventive Cardiology and is on the Editorial Board of cardiovascular journals, such as the Journal of Hypertension, Hypertension Research, Journal of Clinical Hypertension, Journal of Human Hypertension, Current Hypertension Reports and BMC Medicine. She is a Board Member of the Australian Cardiovascular Alliance, Fellow of the European Society of Cardiology, the International Society of Hypertension and the Royal Society of South Africa; the Past President of the Southern African Hypertension Society (SAHS); and Past President of the International Society of Hypertension (ISH).

Click here to access our new membership portal and the FREE 5 hour mini -series OUTSMART OBESITY, HEART DISEASE & CANCER EVENTSClick here to get the OUTSMART BOOKClick here to get the OUTSMART HEALTH LABClick here to get the OUTSMART CLASSROOMClick here if you are a teacherClick here if you are a Cardiology practice or allied health professionalClick here to learn about Shane.In today's episode, I have a phenomenal treat that I've never done before. You are going to meet Professor Alta Schutte. In addition to this, you were going to get access to the full video episode with animation overlay describing what Dr Schutte and I talk about in the interview.Here is the background of todays' guest. Alta (Aletta E.) Schutte PhD FESC FRRSAf ISHF is SHARP Professor and Principal Theme Lead of Cardiac, Vascular and Metabolic Medicine in the Faculty of Medicine and Health at UNSW Sydney, Australia; with a joint appointment as Professorial Fellow at the George Institute for Global Health. She is a NHMRC Investigator Grant Leadership Fellow.She has extensive experience in working in clinical and population-based studies with a focus on raised blood pressure, hypertension and cardiovascular disease. She has been the Chief Investigator of several multidisciplinary studies, published >400 papers in the field of blood pressure and cardiovascular disease, and supervised over 85 postgraduate students. She is involved in numerous international consortia, such as the Global Burden of Disease study (Washington DC), the NCD Risk Factor Collaboration (London), May Measurement Month initiative of the International Society of Hypertension, and was one of 20 invited authors to join the Lancet Commission of Hypertension. She is the senior author of the 2020 International Society of Hypertension Global Hypertension Guidelines.She has been acknowledged for her work as winner of the Distinguished Woman Scientist in the Natural, Engineering and Life Sciences award, presented by the South African Department of Science and Technology; the NSTF South 32 TW Kambule Award; the British Association Medal from the Southern Africa Association for the Advancement of Science, the Meiring Naude Medal from the Royal Society of South Africa, the AU-TWAS (African Union & The World Academy of Sciences) Award, the 2019 African Union Kwame Nkrumah Regional Award for Scientific Excellence, 2020 KIFRA Prize in Science and 2022 Harriet Dustan Award of the American Heart Association's Hypertension Council.She serves as Associate Editor of Hypertension and the European Journal of Preventive Cardiology and is on the Editorial Board of cardiovascular journals, such as the Journal of Hypertension, Hypertension Research, Journal of Clinical Hypertension, Journal of Human Hypertension, Current Hypertension Reports and BMC Medicine. She is a Board Member of the Australian Cardiovascular Alliance, Fellow of the European Society of Cardiology, the International Society of Hypertension and the Royal Society of South Africa; the Past President of the Southern African Hypertension Society (SAHS); and Past President of the International Society of Hypertension (ISH).

Click here to access our new membership portal and the FREE 5 hour mini -series OUTSMART OBESITY, HEART DISEASE & CANCER EVENTSClick here to get the OUTSMART BOOKClick here to get the OUTSMART HEALTH LABClick here to get the OUTSMART CLASSROOMClick here if you are a teacherClick here if you are a Cardiology practice or allied health professionalClick here to learn about Shane.In today's episode, I have a phenomenal treat that I've never done before. You are going to meet Professor Alta Schutte. In addition to this, you were going to get access to the full video episode with animation overlay describing what Dr Schutte and I talk about in the interview.Here is the background of todays' guest. Alta (Aletta E.) Schutte PhD FESC FRRSAf ISHF is SHARP Professor and Principal Theme Lead of Cardiac, Vascular and Metabolic Medicine in the Faculty of Medicine and Health at UNSW Sydney, Australia; with a joint appointment as Professorial Fellow at the George Institute for Global Health. She is a NHMRC Investigator Grant Leadership Fellow.She has extensive experience in working in clinical and population-based studies with a focus on raised blood pressure, hypertension and cardiovascular disease. She has been the Chief Investigator of several multidisciplinary studies, published >400 papers in the field of blood pressure and cardiovascular disease, and supervised over 85 postgraduate students. She is involved in numerous international consortia, such as the Global Burden of Disease study (Washington DC), the NCD Risk Factor Collaboration (London), May Measurement Month initiative of the International Society of Hypertension, and was one of 20 invited authors to join the Lancet Commission of Hypertension. She is the senior author of the 2020 International Society of Hypertension Global Hypertension Guidelines.She has been acknowledged for her work as winner of the Distinguished Woman Scientist in the Natural, Engineering and Life Sciences award, presented by the South African Department of Science and Technology; the NSTF South 32 TW Kambule Award; the British Association Medal from the Southern Africa Association for the Advancement of Science, the Meiring Naude Medal from the Royal Society of South Africa, the AU-TWAS (African Union & The World Academy of Sciences) Award, the 2019 African Union Kwame Nkrumah Regional Award for Scientific Excellence, 2020 KIFRA Prize in Science and 2022 Harriet Dustan Award of the American Heart Association's Hypertension Council.She serves as Associate Editor of Hypertension and the European Journal of Preventive Cardiology and is on the Editorial Board of cardiovascular journals, such as the Journal of Hypertension, Hypertension Research, Journal of Clinical Hypertension, Journal of Human Hypertension, Current Hypertension Reports and BMC Medicine. She is a Board Member of the Australian Cardiovascular Alliance, Fellow of the European Society of Cardiology, the International Society of Hypertension and the Royal Society of South Africa; the Past President of the Southern African Hypertension Society (SAHS); and Past President of the International Society of Hypertension (ISH).

Physiological Reviews Editor-in-Chief Dr. Sadis Matalon speaks with Prof. Rebecca M. Reynolds, Prof. Sarah J. Stock, and Prof. Hilary O. D. Critchley about their editorial “Pregnancy and the SARS-CoV-2 Pandemic,” published in the July 2022 issue of Physiological Reviews. The authors also have contributed a review article on this topic, “Pregnancy and COVID-19,” which was one of the most highly cited articles published in the journal in 2021. Prof. Reynolds is Professor of Metabolic Medicine at the University of Edinburgh. Her research looks at the ways in which early development in utero can affect health and disease. Prof. Stock is Professor of Maternal and Fetal Health at the University of Edinburgh. Her research examines efforts at reducing preterm birth, stillbirth, and other complications in pregnancy. Prof. Critchley has held a Personal Chair in Reproductive Medicine at the University of Edinburgh since 1999. She is Head of the Deanery of Clinical Sciences at the University of Edinburgh, she is Co-Director of the Medical Research Council Centre for Reproductive Health, and she is Consultant Gynaecologist at the Royal Infirmary in Edinburgh. Her research is aimed at improving our understanding of the basic science of the uterine endometrium. She is an Associate Editor of Physiological Reviews. Author introductions [0:41] Efficacy of vaccination in diminishing the severity and long-term consequences of COVID-19 [6:44] Does COVID-19 vaccination cause any significant side effects for the pregnant woman or the fetus? [8:08] Are women who are pregnant at higher risk for COVID infection, and can the virus cross the placenta? [15:53] Does SARS-CoV-2 affect the development of preeclampsia? [21:19] What kinds of treatments are available -- and safe -- for pregnant women with COVID? Are there any animal models in which interventions may be tested? [24:05] What other work is being conducted on this topic? [28:38] Discussion of the effects of SARS-CoV-2 infection or COVID vaccination on menstruation [31:27] Closing remarks [35:59] Subscribe to the podcast here. Browse recent articles on our website. Subscribe to the podcast on Apple Podcasts, Google Podcasts, Spotify, and Amazon Music to receive immediate notification when new episodes are available. Be sure to let your colleagues know about the podcast, and please rate and review it wherever you listen to it. Follow the journal on Twitter and on Facebook. Listen to other podcasts produced by the American Physiological Society.

CURTIS KUHN - The Metabolic Institute, LLC - The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. *** AND NOW ***The ‘X' Zone TV Channel on SimulTV - www.simultv.comThe ‘X' Zone TV Channel Radio Feed (Free - No Subscription Required) - https://www.spreaker.com/show/xztv-the-x-zone-tv-show-audio The ‘X' Chronicles Newspaper - www.xchroniclesnewspaper.com (Free)To contact Rob McConnell - misterx@xzoneradiotv.com

Dr. Shabnam Das Kar MD, FMNM is a doctor, a specialist in Functional and Metabolic Medicine, and an international speaker. Before transitioning into Functional Medicine she was practicing as an Obstetrician Gynaecologist for more than 20 years in Mumbai. She lives in Calgary, Canada, and Mumbai, India. TRAINING AND CREDENTIALS MBBS and MD (OB-GYN) from India Fellow, American Academy of Anti-Aging Medicine (A4M), USA. Advanced Endocrinology Certification from Metabolic Medical Institute (MMI) Special training from Metabolic Medicine Institute on Functional Medicine approach to Autoimmune Diseases Brain Health Coaching Certification from Amen Clinics, USA. Trained in The Clinical Practice of Alzheimer's Prevention From Alzheimer's Universe Tiny Habits Certified Coach WORK Director of Medical Education at Better Medical Centre, Canada. Guest Faculty Member at the Maryland University of Integrative Health in Professional Continuing Education. Speaker at medical conferences in Asia and Canada. In this episode: Dr. Kar's personal and professional journey Bioidentical hormones Vitamin & Mineral Deficiency and Therapeutic Supplementation Protein & Fats Ketones & Glucose Fasting & Time Restricted Eating (TRE) What to expect when working with Dr. Kar Sugar & Mood What's next? Signature Question Follow Dr. Das Kar: Website: https://drkarmd.com/ Twitter: https://mobile.twitter.com/karshabnam The content of our show is educational only. It does not supplement or supersede your healthcare provider's professional relationship and direction. Always seek the advice of your physician or other qualified mental health providers with any questions you may have regarding a medical condition, substance use disorder, or mental health concern.

Dr Sandra Sirrs returns to the podcast to discuss her work developing training competencies for adult metabolic medicine. Training competencies in adult metabolic medicine: A survey of working adult metabolic medicine physicians Sandra Sirrs, et al https://doi.org/10.1002/jmd2.12312 The right tool for the job—Fit for purpose training programs in adult metabolic medicine Annalisa Sechi, et al https://doi.org/10.1002/jimd.12511

Filomena Trindade, MD, MPH, ABFM, ABOIM, FAARM, IFMCP is a physician, teacher, author, and internationally sought after lecturer in functional medicine. She is faculty at the Institute for Functional Medicine (IFM) and in the fellowship program in Metabolic Medicine at Metabolic Medical Institute (MMI).   After obtaining her BA degree in Biology she went on to finish a master's in Public Health in the area of environmental health and epidemiology before starting medical school. She graduated first in her class in family practice from the University of California Davis School of Medicine and did her residency training in family practice at the U.C. San Francisco/Santa Rosa Program.   She has been in clinical practice for over 24 years. Before starting her own private practice in 2004 in functional medicine she was the medical director of a non-profit organization that catered to the underserved.   She recently authored a chapter on Nutritional Influences on Hormonal Health in the Integrative and Functional Medicine Nutrition Therapy Textbook and another chapter on Diabetes in the Integrative Cardiovascular Medicine textbook. Other publications include Townsend Letter, Guide to Anti- Aging & Regenerative Medicine, Saúde Actual, and the Border Health Journal.   She is currently very active in her Saudade Certification Program, in mentoring other health providers and in her health retreats in Azores, her homeland. Keep up with her activities at www.drtrindade.com.

Welcome to the Siim Land Podcast, I'm your host Siim Land and today our guest is Greg Potter. Greg. Greg has a PhD in the Leeds University of Cardiovascular and Metabolic Medicine. His research focuses on circadian rhythms and light-dark cycles. Greg is also one of the founders of Resilient Nutrition that provides functional food products for long endurance sports, such as almond butters and chocolate with added L-theanine, whey protein, leucine and other adaptogens. This episode is brought to you by the world's most recognized probiotic supplement SEED. Seed's Daily Synbiotic is a pre-and-probiotic 2-in-1 capsule that supports your gut health, skin, digestion, and so much more. SEED isn't a cocktail of random strains of bacteria that do nothing. It contains 24 clinically and scientifically studied strains, which makes SEED the first of its kind. On top of that, the package is delivered sustainably. In your first purchase, you'll get a glass jar that is infinitely refillable. Your monthly refills are delivered in compostable, biodegradable, and recyclable packaging. SEED's Daily Synbiotic is the only probiotic supplement I'm taking regularly because of how much it's backed by research. I notice the benefits it has on my digestion and overall energy. Get 15% off your first month's supply of Seed's Daily Synbiotic by visiting seed.com/SIIM15 or by using code SIIM15 at checkout. Timestamps: 01:15 Greg's Recent Life Events 03:10 Sleep Deprivation and Performance 06:20 Shift Work 11:00 Is Napping Healthy 18:10 Should You Take a Nap 24:05 What Are Chronotypes 29:00 Do You Need to Stick to Your Chronotypes 34:10 Effect of Daylight on Circadian Rhythms 40:25 How Much Daylight You Should Get Exposed To 44:10 Exercise and Sleep Quality 49:00 How to Prepare for a Short Night Sleep 01:03:35 How to Recover From Bad Sleep 01:13:11 Sleep Drive and Falling Asleep And much more Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body.  With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That's an AMAZING value. And I promise that deal is ONLY available on this specific website,  Click Here to Support the Show on Patreon!   Show Notes Use Code SIIM15 for a Discount Off SEED Probiotic The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim      

Today we're joined by Professor Naveed Sattar for a summary of some of the key takeaways from the International Diabetes Federation Virtual Congress 2021. Professor Sattar is Professor of Metabolic Medicine at the University of Glasgow, and was Committee Lead for the Cardiovascular Disease & Hypertension stream at the congress. For more free education, go to diabetes.knowledgeintopractice.com, where you can see all past episodes of the podcast as well as other free CME resources. Follow us on Twitter (@dkipractice) or connect on LinkedIn. Disclosures: Professor Naveed Sattar declares the following: Advisory board: Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Merck Sharp & Dohme, Novartis, Novo Nordisk, Pfizer, Sanofi Speaker honoraria: Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Novo Nordisk, Sanofi Institutional research grant: Boehringer Ingelheim All conflicts have been mitigated prior to this activity. This independent educational activity is supported by an educational grant from Novo Nordisk A/S. The educational content has been developed by Liberum IME in conjunction with an independent steering committee; Novo Nordisk A/S has had no influence on the content of this education.

The Beat podcast is designed for healthcare professionals only and is brought to you by Nutricia.  In this mini-series we explore the world of metabolic medicine, meeting the people from the multi disciplinary team who deliver the service. Through these episodes we hear what a typical day in the life of these experts is like, what they have learnt in their career and what is still to be discovered in the fascinating world of Metabolics.  In this episode of The Beat podcast, host Dr James Nurse, Consultant Paediatrician, is joined by  Dr. Arunabha Ghosh , a Consultant Paediatrician working in Metabolic Medicine. We hear about the impressive training journey taken to reach his role, the interesting research he is involved in and what the role entails day to day.

The Beat podcast is designed for healthcare professionals only and is brought to you by Nutricia.  In this mini-series we explore the world of metabolic medicine, meeting the people from the multi disciplinary team who deliver the service. Through these episodes we hear what a typical day in the life of these experts is like, what they have learnt in their career and what is still to be discovered in the fascinating world of Metabolics.  In this episode of The Beat podcast, host Dr James Nurse, Consultant Paediatrician, is joined by Dr Penny Andreou, a Senior Clinical Psychologist working in Paediatric Metabolic Medicine. They discuss the crucial  role a psychologist plays within the MDT, the type of work she does with children and their families and the importance of ensuring different services are connected. 

The Beat podcast is designed for healthcare professionals only and is brought to you by Nutricia.  In this mini-series we explore the world of metabolic medicine, meeting the people from the multi disciplinary team who deliver the service. Through these episodes we hear what a typical day in the life of these experts is like, what they have learnt in their career and what is still to be discovered in the fascinating world of Metabolics.  In this episode of The Beat podcast, host Dr James Nurse, Consultant Paediatrician, is joined by Georgie Wood, a newly qualified Dietitian and her mentor Dr Anita Macdonald, Consultant Dietitian working in Metabolic Medicine. This episode is packed full of advice, insights and we learn how the training has evolved over the past 40 years.

CURTIS KUHN - The Metabolic Institute, LLC - The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. *** AND NOW ***The ‘X' Zone TV Channel on SimulTV - www.simultv.comThe ‘X' Zone TV Channel Radio Feed (Free - No Subscription Required) - https://www.spreaker.com/show/xztv-the-x-zone-tv-show-audio The ‘X' Chronicles Newspaper - www.xchroniclesnewspaper.com (Free)To contact Rob McConnell - misterx@xzoneradiotv.com

CURTIS KUHN - The Metabolic Institute, LLC - The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. *** AND NOW *** The ‘X' Zone TV Channel on SimulTV - www.simultv.com The ‘X' Zone TV Channel Radio Feed (Free - No Subscription Required) - https://www.spreaker.com/show/xztv-the-x-zone-tv-show-audio The ‘X' Chronicles Newspaper - www.xchroniclesnewspaper.com (Free) To contact Rob McConnell - misterx@xzoneradiotv.com

CURTIS KUHN - The Metabolic Institute, LLC - The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. *** AND NOW ***The ‘X' Zone TV Channel on SimulTV - www.simultv.comThe ‘X' Zone TV Channel Radio Feed (Free - No Subscription Required) - https://www.spreaker.com/show/xztv-the-x-zone-tv-show-audio The ‘X' Chronicles Newspaper - www.xchroniclesnewspaper.com (Free)To contact Rob McConnell - misterx@xzoneradiotv.com

CURTIS KUHN - The Metabolic Institute, LLC - The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. *** AND NOW *** The ‘X' Zone TV Channel on SimulTV - www.simultv.com The ‘X' Zone TV Channel Radio Feed (Free - No Subscription Required) - https://www.spreaker.com/show/xztv-the-x-zone-tv-show-audio The ‘X' Chronicles Newspaper - www.xchroniclesnewspaper.com (Free) To contact Rob McConnell - misterx@xzoneradiotv.com

Today's guest is empowering people to lead full, vibrant, and authentic lives. Her message is strong yet simple: take exquisite care of yourself, respect the choices you make, and tune in to healing from the inside out. She is passionate about bringing the heart and soul back into the practice of Medicine. She is a Family Physician, Certified Wellness & Lifestyle Empowerment Coach, Motivational Speaker, and Author. She holds a Degree in Alternative Medicine and is Board Certified in Anti-Aging, Regenerative and Metabolic Medicine, as well as an Integrative Health Coaching Certification from the Institute for Integrative Nutrition (IIN). With her unique blend of Western medicine, Lifestyle coaching, and Integrative health, she has distinguished herself as a Women's Wellness Warrior. Please give a very warm welcome to today's special guest, Tanya Beaubrun! Top 3 Amplifiers: 1. Ways on how to look into Functional and Integrative Medicine 2. The future of medicines 3. The value of Traditional Medicines To listen, find other episodes, access the show notes, and find out more go to www.amplifyto7figures.com. Enter the giveaway here: https://amplifyto7figures.com/giveaway Connect with today's guest: Book: Bubbles, Buddha, and Butterflies - https://www.amazon.com/Bubbles-Buddha-Butterflies-Butterfly-Without-ebook/dp/B08L3B4NZ1 Facebook: https://www.facebook.com/ Instagram: https://www.instagram.com/drtanyabeaubrun/

Kendal Williams, MD, MPH, is joined by Rani Nandiwanda, MD, and Anastassia Amaro, MD, the medical director of the Obesity and Metabolic Center at Penn Medicine, to discuss the primary care management of obesity. They review both dietary approaches and the latest pharmacological options for obesity.

The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. - www.themetabolicinstitute.com To listen to all our XZBN shows, with our compliments go to: https://www.spreaker.com/user/xzoneradiotv*** AND NOW ***The ‘X' Zone TV Channel on SimulTV - www.simultv.comThe ‘X' Chronicles Newspaper - www.xchroniclesnewpaper.com

The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. - www.themetabolicinstitute.com To listen to all our XZBN shows, with our compliments go to: https://www.spreaker.com/user/xzoneradiotv*** AND NOW ***The ‘X' Zone TV Channel on SimulTV - www.simultv.comThe ‘X' Chronicles Newspaper - www.xchroniclesnewpaper.com

FILOMENA TRINDADE, MD, MPH obtained her BA degree in biology and went on to finish a Master's in Public Health in the area of environmental health and epidemiology before starting medical school. She graduated first in her class in family practice from the University of California Davis School of Medicine and did her residency training in family practice at the U.C. San Francisco/Santa Rosa Program. Filomena has been in clinical practice for over 23 years. She is faculty at the Institute for Functional Medicine (IFM) and in the fellowship program in Metabolic Medicine at Metabolic Medical Institute (MMI).

Breath control in physical and mental health as it enhances performance both on and off the field. About Michael Miletic, MD Advancing the field of brain-body-mind science for your best health. Dr. Michael Miletic is a former Olympic athlete and a prominent physician specializing in clinical neuroscience and integrative metabolic medicine. Dr. Miletic evaluates the brain, mind, and body and brings the latest science and evidence-based treatments to optimize your health. He specializes in athletes, executives, and adolescents looking to reach their full potential. Dr. Miletic's comprehensive training and evidence-based research have enabled him to understand something many healthcare providers do not: approaches that treat the body without addressing the mind are limited in their effectiveness. Getting to know you, your life experiences, and the way you think and feel is thus a critical aspect of the care you receive from Dr. Miletic. Dr. Miletic developed “The Miletic Method” as a new model of mental health treatment, brain functioning, performance, longevity, and health. The model consists of looking at the brain/body as a series of interrelated bidirectional systems influencing and influenced by each other in ways specific to each patient. Understanding the intricacies of this allows us to approach each patient in an individualized way. The method then involves integrating all of the physical measures through history taking and specialized lab tests with psychology and neuroscience in a way that provides a new understanding of mental states and psychiatric diagnoses. Some of the aspects of your health that are measured and evaluated include hormone balance, micronutrients levels, neurotransmitter levels, gut health, inflammation, stress, immune response, life events and trauma. Based on an initial assessment of your physical and mental health and your personal health goals, Dr. Miletic will provide a personalized treatment plan. As he monitors your body's response to this plan, he will adapt and optimize treatment until the desired results are achieved. Dr. Miletic earned his medical degree from the University of Western Ontario Medical School and completed his residency in Psychiatry at the Detroit Medical Center. He is Board Certified in Psychiatry, Neurology and Metabolic Medicine. He is also certified in Psychoanalysis and serves as an Advanced Fellow in Metabolic Medicine. He is licensed in both the United States and Canada, and his practice is based in Bloomfield Hills, Michigan. Follow Dr. Miletic TheMileticCenter.com is the primary website. On Instagram - Michael Miletic. Instagram.com/michaelmiletic/ On Facebook - The Miletic Center https://www.facebook.com/themileticcenter Upcoming Books & Courses 'The Athletes Mind' and “The Inner Game”

In this episode, sponsored by bit.bio,  Drs. Marius Wernig and Yi Han Ng join the podcast to talk about the directed differentiation of pluripotent stem cells into dopaminergic neurons. Their approach, which is based on the expression of specific transcription factors to drive cell fate directly to a specific neuronal identity, has been demonstrated to robust generalate functional dopaminergic neurons of midbrain character.GuestsMarius Wernig, MD, PhD, Associate Professor of Pathology at the Institute for Stem Cell Biology and Regenerative Medicine at Stanford UniversityWebsite: https://www.werniglab.org/Yi Han Ng, PhD, Institute for Stem Cell Biology and Regenerative Medicine and Department of Pathology, Stanford University School of Medicine and Laboratory of Metabolic Medicine, Singapore Bioimaging Consortium, Agency for Science, Technology and Research, SingaporeSupporting DocumentsEfficient Generation of Dopaminergic Induced Neuronal Cells with Midbrain Characteristics HostMartin Pera, PhD: Editor-in-Chief, Stem Cell Reports and The Jackson LaboratoryTwitter: @martinperaJAX  About Stem Cell ReportsStem Cell Reports is the open access journal of the International Society for Stem Cell Research for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.Twitter: @StemCellReportsAbout ISSCRWith nearly 4,000 members from more than 65 countries, the International Society for Stem Cell Research is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.Twitter: @ISSCR AcknowledgementsISSCR StaffKeith Alm, Chief Executive OfficerBethany Almon, Senior Manager of Integrated MarketingYvonne Fisher, Managing Editor, Stem Cell ReportsKym Kilbourne, Director of Media and Strategic CommunicationsJack Mosher, Senior Manager of Scientific AffairsVoice WorkJulie PerlinBen SnitkoffMusic@Konovalov

The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. - www.themetabolicinstitute.com******************************************************************To listen to all our XZBN shows, with our compliments go to: https://www.spreaker.com/user/xzoneradiotv*** AND NOW ***The ‘X' Zone TV Channel on SimulTV - www.simultv.comThe ‘X' Chronicles Newspaper - www.xchroniclesnewspaper.com ******************************************************************

The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. - www.themetabolicinstitute.com For Your Listening Pleasure all the radio shows available on The 'X' Zone Broadcast Network with our compliments, visit - https://www.spreaker.com/user/xzoneradiotv. Our radio shows archives and programming include: A Different Perspective with Kevin Randle; Alien Cosmic Expo Lecture Series; Alien Worlds Radio Show; America's Soul Doctor with Ken Unger; Back in Control Radio Show with Dr. David Hanscom, MD; Connecting with Coincidence with Dr. Bernard Beitman, MD; Dick Tracy; Dimension X; Exploring Tomorrow Radio Show; Flash Gordon; Imagine More Success Radio Show with Syndee Hendricks and Thomas Hydes; Jet Jungle Radio Show; Journey Into Space; Know the Name with Sharon Lynn Wyeth; Lux Radio Theatre - Classic Old Time Radio; Mission Evolution with Gwilda Wiyaka; Paranormal StakeOut with Larry Lawson; Ray Bradbury - Tales Of The Bizarre; Sci Fi Radio Show; Seek Reality with Roberta Grimes; Space Patrol; Stairway to Heaven with Gwilda Wiyaka; The 'X' Zone Radio Show with Rob McConnell; Two Good To Be True with Justina Marsh and Peter Marsh; and many other! That's The ‘X' Zone Broadcast Network Shows and Archives - https://www.spreaker.com/user/xzoneradiotv

The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. - www.themetabolicinstitute.comFor Your Listening Pleasure all the radio shows available on The 'X' Zone Broadcast Network with our compliments, visit - https://www.spreaker.com/user/xzoneradiotv.Our radio shows archives and programming include: A Different Perspective with Kevin Randle; Alien Cosmic Expo Lecture Series; Alien Worlds Radio Show; America's Soul Doctor with Ken Unger; Back in Control Radio Show with Dr. David Hanscom, MD; Connecting with Coincidence with Dr. Bernard Beitman, MD; Dick Tracy; Dimension X; Exploring Tomorrow Radio Show; Flash Gordon; Imagine More Success Radio Show with Syndee Hendricks and Thomas Hydes; Jet Jungle Radio Show; Journey Into Space; Know the Name with Sharon Lynn Wyeth; Lux Radio Theatre - Classic Old Time Radio; Mission Evolution with Gwilda Wiyaka; Paranormal StakeOut with Larry Lawson; Ray Bradbury - Tales Of The Bizarre; Sci Fi Radio Show; Seek Reality with Roberta Grimes; Space Patrol; Stairway to Heaven with Gwilda Wiyaka; The 'X' Zone Radio Show with Rob McConnell; Two Good To Be True with Justina Marsh and Peter Marsh; and many other!That's The ‘X' Zone Broadcast Network Shows and Archives - https://www.spreaker.com/user/xzoneradiotv

In this episode, Lucas invites Dr. Michael Miletic on the show. Dr. Miletic earned his medical degree from the University of Western Ontario Medical School and completed his residency in Psychiatry at the Detroit Medical Center. He is Board Certified in Psychiatry, Neurology, and Metabolic Medicine. He is also certified in Psychoanalysis and serves as an Advanced Fellow in Metabolic Medicine. While completing his medical degrees, Dr. Miletic was Canadian Olympic weightlifting champion (1982), Pan-American games Silver Medalist (1983), and a member of the Canadian Olympic weightlifting team (1984).  Relevant links:Dr. Miletic’s Website: https://themileticcenter.com/ 

In this episode, Lucas invites Dr. Michael Miletic on the show. Dr. Miletic earned his medical degree from the University of Western Ontario Medical School and completed his residency in Psychiatry at the Detroit Medical Center. He is Board Certified in Psychiatry, Neurology and Metabolic Medicine. He is also certified in Psychoanalysis and serves as an Advanced Fellow in Metabolic Medicine. While completing his medical degrees, Dr. Miletic was Canadian Olympic weightlifting champion (1982), Pan-American games Silver Medalist (1983) and a member of the Canadian Olympic weightlifting team (1984).   Relevant links:Dr. Miletic’s Website: https://themileticcenter.com/ 

Dr. Marra’s goal as a Naturopathic doctor specializing in vector-borne illnesses including: chronic fatigue, fibromyalgia, and associated diseases is to provide progressive, integrated and individualized healthcare to all of her patients while working toward optimal function and health. Dr. Marra has over 22 years of experience successfully diagnosing and treating Borreliosis/tick-borne illness, and has helped over 10,000 patients return to health.  Additionally, Dr. Marra has been completely successful in overcoming her own battle with Borreliosis/Lyme disease, and has been symptom free for more than seven years.  Her personal road to recovery aids her in understanding the difficulties patients experience on the healing journey, and heightens her compassion for patients in search of a proper diagnosis and subsequent treatment.   Dr. Marra is Board Certified and a Fellow in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine, and is a Fellow in Metabolic Medicine through the Metabolic Medical Institute. She is also recently certified in nutritional genomic consulting through the Nutrigenetic Research Institute. Dr. Marra uses a variety of skills to help her patients heal from tick borne illness, and believes that nutrigenomics is paving the way for a better understanding of the epigenetic environmental factors that contribute to people becoming ill with tick borne illness. She regularly attends seminars, workshops, and conferences to advance her knowledge and remain at the forefront of this new era of medicine.

Cardiovascular disease is the biggest cause of mortality among people with type 1 and type 2 diabetes, with chronic hyperglycaemia causing vascular damage, while in type 2 diabetes other risk factors may also present in the prediabetes phase. This episode discusses the importance of optimising control of cardiovascular risk factors such as blood pressure, lipids and smoking status, with Prof. Naveed Sattar, Professor of Metabolic Medicine at the University of Glasgow. Do you have a question for our expert faculty? This series will feature episodes aiming to address areas with unanswered clinical questions; first up we will be speaking to Prof. Stephen Bain about offering cardioprotective agents in type 2 diabetes. Send any questions to contact@knowledgeinpractice.eu or message us on Twitter/LinkedIn. For more free education, visit the DKIP website, follow us on Twitter (@dkipractice) or connect on LinkedIn. References: Welsh C et al. Diabetes Care. 2019 Dec;43(2):44-445 McAllister D et al. Circulation. 2018 Dec 11;138(24):2774-2786 Thomas M. Adv Chronic Kidney Dis. 2014 May;21(3):311-7 Buse J et al. Diabetes Care. 2020 Feb;43(2):487-493 Cosentino F et al. Eur Heart J. 2020 Jan 7;41(2):255-323 American Diabetes Association. Diabetes Care 2021 Jan; 44(Supplement 1) Disclosures: Professor Naveed Sattar declares the following: Advisory board: Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Merck Sharp & Dohme, Novartis, Novo Nordisk, Pfizer, Sanofi Speaker honoraria: Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Novo Nordisk, Sanofi Institutional research grant: Boehringer Ingelheim Funding statement: This independent educational activity is supported by an educational grant from Eli Lilly, Merck Sharp & Dohme Corp and Novo Nordisk A/S. The educational content has been developed by Liberum IME in conjunction with an independent steering committee; the financial supporters have had no influence on the content of this education.

Dr Monaco delivers his presentation on Low Dose Naltrexone (LDN) as part of the LDN Book Volume 2 Tour which took place virtually in October 2020. Hosted by Madison Drugs. Dr. Monaco received his medical degree from Wake Forest University School of Medicine (Bowman Gray School of Medicine). He completed a residency in Obstetrics & Gynecology and was in private practice for more than 25 years in Hartford, CT. He completed an advanced Fellowship in Anti Aging, Functional and Metabolic Medicine in 2007 from the American Academy of Anti Aging Medicine (A4M) and opened the Monaco Center for Health & Healing in 2008. In 2014, he relocated his practice to Nashville Tennessee and opened the Nashville Hormone & Integrative Medicine Center now located in Franklin, TN.  He has lectured throughout the United States, Canada and the Middle East on Hormone restoration, adrenal and thyroid dysfunction, autoimmunity and intestinal dysfunction. He is a past Oral Board examiner and faculty member for A4M, teaching on Hormone restoration, Adrenal and Thyroid Dysfunction, autoimmunity and Hormones and Cardio-metabolic Disease. He has been a speaker for A4M, ZRT laboratories, PCCA, Metagenics and Biotics Research.

Join Drs. Heyman and Swidan as they discuss the transition of education in the world of Anti-Aging, Integrative and Functional medicine. Dr Swidan is President and CEO of Pharmacy Solutions in Ann Arbor, MI and Adjunct Associate Professor of Clinical Research and Leadership at George Washington University School of Medicine and Health Sciences, and Adjunct Clinical Associate Professor of Pharmacy at Wayne State University. She received her Doctor of Pharmacy degree and completed a 3-year research Fellowship in Bio-Pharmaceutics and Gastroenterology at the University of Michigan. Following her fellowship, she was Director of Pharmacy at Chelsea Community Hospital and the clinical pharmacist for the inpatient head and chronic pain service. Dr. Swidan is board certified and an advanced fellow in anti-aging and regenerative medicine. She is an internationally renowned speaker in the areas of pain management, headaches, and HRT. She has authored several book chapters, articles, and patient education material in head and general pain management and personalized medicine. Dr. Swidan co-edited and authored a book with many thought leaders from around the globe titled Advanced Therapeutics in Pain Medicine which aids clinicians in advancing their current toolbox in the treatment of various pain syndromes. Andrew Heyman, MD, MHSA is an internationally recognized expert in Integrative Medicine. He is currently the Program Director of Integrative and Metabolic Medicine at The George Washington University. Prior to assuming this role, he spent 16 years at the University of Michigan, serving to build one of the largest and most successful academic-based Integrative Medicine programs in the United States. Dr. Heyman has held several leadership positions in the field of Integrative Medicine. He was the national clinical working group co-chair of the Consortium of Academic Health Centers for Integrative Medicine for 4 years, a collaboration of 57 North American universities involved in Integrative Medicine. He is the online editor for the Journal of Men's Health in the section of Integrative Medicine, and he also holds the position of Editor-In-Chief of the Internet Journal of Anti-Aging and Aesthetic Medicine. His research interests include the Stress response and NeuroEndocrinology, Cardiometabolic Disease, Men's Health and clinical outcomes research methodologies. Dr. Heyman remains clinically active as well, as the owner of a four-physician integrative medicine practice in Northern Virginia at the Virginia Center for Health and Wellness. He is also the President of Integrative Health Resources, a small group of clinical experts that consults to physicians, health systems and public health professionals seeking to develop wellness, lifestyle and nutrition programs.

Watch the full video interview on YouTube here: https://bit.ly/tanaamen392 Tana Amen (IG: @tanaamen) is a New York Times bestselling author, vice president of the Amen Clinics, a neurosurgical ICU trauma nurse, and a world-renowned health and fitness expert. She has won the hearts of millions with her simple yet effective strategies to help anyone optimize their lifestyle and win the fight for a strong body, mind, and spirit. Tana holds a second-degree black belt in Kenpo Karate and a black belt in Tae Kwon Do. Tana and her husband, Dr. Daniel Amen, have four children and five grandchildren. Today we’re discussing her new book: The Relentless Courage of a Scared Child: How Persistence, Grit, and Faith Created a Reluctant Healer. In this episode, we discuss: How we were all scared children at one time The epiphany Tana had working with addicts Tana’s first 3 memories as a child Growing up in constant chaos Tana's mom always showed she loved her Dealing with unwanted attention and bullying during her teen years Battling an eating disorder, anxiety, and depression Tana was diagnosed with thyroid cancer at age 23 How Prozac hijacked her brain The spiritual walk that lead to Tana’s healing journey Responsibility means the ability to respond Falling in love with her best friend, Dr. Daniel Amen Working with Byron Katie Eye movement desensitization and reprocessing (EMDR) therapy can help with trauma Lifestyle factors including food, nutrition, and exercise impact your health Be your own best advocate Your doctor is not your boss, they are your partner Tana’s life-changing journey studying Metabolic Medicine and Functional Medicine Implementing the Omni diet at Amen Clinics Consciously raising her daughter Chloe in a healthy environment The vulnerable truth about writing a memoir Processing past trauma through the eyes of an adult Helping her half sister and taking custody of her 2 nieces Forgiving her dad before he passed away The powerful need for forgiveness Show sponsors: Paleovalley

Lead author, Dr. Klaus Witte, Senior Lecturer and Consultant Cardiologist, University of Leeds and Leeds General Infirmary, discusses findings from a new economic study titled "Cost-effectiveness of an insertable cardiac monitor to detect atrial fibrillation in patients with cryptogenic stroke". Results were recently published in the Journal of Comparative Effectiveness Research. Klaus Witte is a Senior Lecturer and Consultant Cardiologist in the Leeds Institute of Cardiovascular and Metabolic Medicine at the University of Leeds. He has his own group investigating the relationship between pacemaker therapy and heart failure and also is the Head of the Department of Clinical and Population Science in the Leeds Institute of Cardiovascular and Metabolic Medicine with line management responsibilities for over 40 investigators, fellows and technical staff. His research interests include vitamin D in CHF, and he was principle investigator of VINDICATE, the largest study of vitamin D supplementation in CHF patients (Medical Research Council) showing improved LV function following one year of vitamin D. He was co-investigator on the recently published REM-HF study (Eur Heart J) describing a neutral effect of remote monitoring in CHF patients (British Heart Foundation). He is the only cardiologist in the UK to have held an NIHR (UK) clinician scientist award, in his case for the OPT-pace project, which, with 1800 patients enrolled is the largest ever prospective study to collect information on the relationship between pacemakers and heart failure (EHRA late breaking clinical trials 2019). He has recently published the results of the REDUCE-FMR study describing the potential of a transvenous coronary sinus-based approach to reducing mitral regurgitation in patients with heart failure and reduced ejection fraction (JACC-HF) He has long questioned standard teaching around heart rate and exercise capacity in heart failure (JACC 2016). His group described a reproducible non-invasive technique to measure contractility and plot the force-frequency relationship. Peak contractility in heart failure occurs at a lower heart rate than in health. This finding and two randomised double-blind clinical trials describing the benefit on exercise capacity of programming pacemakers using patients’ force frequency relationship information (JACC-HF 2018, Circulation 2020) have changed the way we view heart rate in heart failure. His interests extend to health economics, specifically the assessment of cost effectiveness of device therapy, where the upfront costs of devices in a population are particularly challenging for payers.

The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. - www.themetabolicinstitute.com

Dr. Dan Watts is an M.D. in Sarasota, FL who began as an OBGYN. He transitioned into Functional and Integrative Medicine 20 years ago and is now Board Certified in 4 specialties with a master’s in Nutritional and Metabolic Medicine. He owns The Renewal Point on Clark Road, where they use holistic and personalized methods to find the root cause of disease and restore health and well-being.

Dr. Dan Watts is an M.D. in Sarasota, FL who began as an OBGYN. He transitioned into Functional and Integrative Medicine 20 years ago and is now Board Certified in 4 specialties with a master’s in Nutritional and Metabolic Medicine. He owns The Renewal Point on Clark Road, where they use holistic and personalized methods to find the root cause of disease and restore health and well-being.

Fatphobia has been described as society's last ‘ism'. Whilst our understanding of weight and health has changed over time, there is still a stigma towards people who are overweight or obese, and an assumption that they must be unhealthy, and unhealthy by choice. However, the correlation between weight and health may not be as clear cut as our societal biases would lead us to believe, and, therefore, the challenge for GPs is to make a conscious efforts to overcome our preconceptions so that they may provide the best support for our obese patients. This week, we discuss the need for a zero tolerance towards fat shaming at an organisational level, and how we can make GP practices more accessible for this group of patients. We also talk about retraining the palette in order to sustain weight loss, and our duty to lobby for better community-based weight management services. Our guests: Stephanie deGiorgio is a GP, and the clinical lead in the UTC at Queen Elizabeth The Queen Mother Hospital, Margate. She has a special interest in obesity. Naveed Sattar is a professor of Metabolic Medicine at the University of Glasgow. His main research concerns investigating the prevention, causes and management of diabetes, heart disease and obesity.

Fatphobia has been described as society's last ‘ism'. Whilst our understanding of weight and health has changed over time, there is still a stigma towards people who are overweight or obese, and an assumption that they must be unhealthy, and unhealthy by choice. However, the correlation between weight and health may not be as clear cut as our societal biases would lead us to believe, and, therefore, the challenge for GPs is to make a conscious efforts to overcome our preconceptions so that they may provide the best support for our obese patients. This week, we discuss the need for a zero tolerance towards fat shaming at an organisational level, and how we can make GP practices more accessible for this group of patients. We also talk about retraining the palette in order to sustain weight loss, and our duty to lobby for better community-based weight management services. Our guests: Stephanie deGiorgio is a GP, and the clinical lead in the UTC at Queen Elizabeth The Queen Mother Hospital, Margate. She has a special interest in obesity. Naveed Sattar is a professor of Metabolic Medicine at the University of Glasgow. His main research concerns investigating the prevention, causes and management of diabetes, heart disease and obesity.

The Metabolic Institute, LLC is a Corporation formed by Dr. Curtis R. Kuhn after 24 years of personal experience on Metabolic Therapy. The core of this nutritional protocol is the science commonly known as "Metabolic Typing." It's founder and scientific creator is Dr. William Donald Kelley, founder of the International Health Institute and co-founder of The College of Metabolic Medicine. As you discover more information about this unique science during your visit to this website, you should know that Dr. Kelley's work has been literally decades ahead of any other nutritional program currently in the world. His current book, "Cancer, Curing The Incurable," was written after three visits to the United States Supreme Court, with the personal case histories of 33,000 patients over a 42 year period. The subtitle says it all : This program is not about remission, it is about a cure!!! Although cancer is a serious disease, there are dozens of other metabolic disorders that can be positively affected by the correct metabolic protocol. We know through Dr. Kelley's research during the past 45 years, that cancer, like most degenerative diseases is also a deficiency disease. A Pancreatic Enzyme Deficiency, combined also with a slight hormonal imbalance. But Dr. Kelley was not the first to prove this, Dr. John Beard in the 19th century, after 20 years of intense clinical research was the first to discover this scientific fact. Metabolic typing is one of Dr. Kelley's major scientific discoveries that addresses each individual Biochemically. This is called "Biochemical Individuality." Just like your finger print, we all have a unique cell print, which genetically determines what type of foods we thrive best on. This premise is based upon the Autonomic Nervous System. Thus nutritional supplements are also designed for each specific metabolic type. As you learn more of this science from our website, you will begin to understand the 12 basic metabolic types and where you may currently be on Dr. Kelley's Metabolic Spiral Of Health. - www.themetabolicinstitute.com

FILOMENA TRINDADE, MD, MPH obtained her BA degree in biology and went on to finish a Master's in Public Health in the area of environmental health and epidemiology before starting medical school. She graduated first in her class in family practice from the University of California Davis School of Medicine and did her residency training in family practice at the U.C. San Francisco/Santa Rosa Program. Filomena has been in clinical practice for over 23 years. She is faculty at the Institute for Functional Medicine (IFM) and in the fellowship program in Metabolic Medicine at Metabolic Medical Institute (MMI). 

This week on Womanity – Women in Unity, Dr. Amaleya Goneos-Malka talks to Professor Tess van der Merwe who is a Professor and Researcher in the Department of Endocrinology, University of Pretoria;  CEO of the 11 Centres for Metabolic Medicine and Surgery of South Africa CEMMS(SA). She is the Africa consultant for the International Association for the Study of Obesity; Chair of the South African Society for Obesity Metabolism (SASSO) and has served this organisation for more than 25 years; and she currently serves on the Scientific Board of the International Federation for Surgical Obesity. She highlights the fact that two out of every three women in South Africa is clinically overweight or obese, which places South Africa fifth highest level in the world in terms of obesity rankings and the heaviest in sub-Sahara Africa. Obesity is a multifactorial disease and the prevalence in women is combination of environmental and personal factors. There is a need to shift thinking about obesity from a lifestyle disease to a disease in its own right that contributes to several chronic diseases, including diabetes, cardiovascular conditions and cancer. We compare gender equality attitudes in South Africa and Sweden (an egalitarian society), where gender blindness in Sweden provides equal opportunities for women in comparison to the immature attitudes some sectors of  South African society tends to have regarding women that limit their development. Tune in for more….

Dr Carolyn Lam: Welcome to Circulation on the Run, your weekly podcast summary, and backstage pass to the journal and its editors. I'm Dr Carolyn Lam, associate editor from the National Heart Center and Duke National University of Singapore. Dr Greg Hundley: I'm Greg Hundley, Associate Editor, Director of the Poly Heart Center at VCU Health in Richmond, Virginia. Dr Carolyn Lam: Today's feature discussion is the first huge look at the global, regional and national burden of calcific aortic valve disease and degenerative mitral valve disease over a huge period, from 1990 to 2017. Very important discussion coming right up after this coffee chat. Greg, do you mind if I go first? Dr Greg Hundley: Go ahead, Carolyn. Dr Carolyn Lam: The first paper I want to talk about applies novel single cell transcriptomics to unveil new insights into pressure overload cardiac hypertrophy. Here's your quiz, Greg, ready? Dr Greg Hundley: Well, I'm choking on my coffee here, but go ahead. Dr Carolyn Lam: All right, I was thinking of asking you about single cell transcriptomics but let me just tell you the results. Single cell RNA sequencing is a new and rapidly advancing technique that can comprehensively characterize gene expression and relationships among individual cells. Dr Wang from Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, and Peking Union Medical College and colleagues analyze the transcriptomes of 11,492 single cells and identified major cell types, including both cardiomyocytes and non-cardiomyocytes based on their molecular signatures. They did this at different stages during the progression of pressure overload induced cardiac hypertrophy in a mouse model. Their findings not only illustrated dynamically changing cell type crosstalk doing pathological cardiac hypertrophy, but also shed light on strategies for cell type and stage specific interventions in cardiac disease. For example, subtype switching of macrophages was found to be a key event underlying the transition from normal to decline dejection fraction in cardiac hypertrophy. Thus, targeting macrophages in hypertrophy for example, during the switch could attenuate disease progression. All of this is discussed in an editorial by doctors, Zhang and Zhou from University of Alabama in Birmingham. Dr Greg Hundley: Oh wow. Carolyn very important macrophage infiltration and another role for those, that cell type. Well, my first paper gets at the topic of reversal of these factor Xa inhibitors. In this particular patient population, it's the situation where we're dealing with intracranial hemorrhage. The article comes from Dr G Morgan Jones and colleagues from the University of Tennessee Health Sciences Center. Since the approval of oral factor Xa inhibitors, there have been few papers published really regarding the ability to neutralize the anti-coagulate effects of these agents, particularly after intercranial hemorrhage. Dr Carolyn, this is a multi-center, retrospective, observational cohort study of 433 patients. Then it received apixaban, or rivaroxaban, and then developed an intercranial hemorrhage. They then subsequently received prothrombin complex concentrates in that period of time between 2015 and 2019. Dr Carolyn Lam: Wow. How did these participants who had intracranial hemorrhage, how did they fare after receiving these prothrombin concentrates? Dr Greg Hundley: Yeah, well, administration of the prothrombin complex concentrates after, apixaban or rivaroxaban in the setting of intracranial hemorrhage, provided a high rate of excellent or good hemostasis. That was in nearly 82%, coupled with an adverse consequence of 3.8% of those experiencing a thrombosis. Thrombosis occurred in 25 patients who had a total of 26 thrombotic events of which 22 occurred in the first 14 days, following the prothrombin complex concentrate administration. One patient had documentation of an infusion related reaction. For the full cohort of patients, in the hospital mortality was 19% and the median ICU care and hospital length of stay were two and six days respectively. Carolyn, these cohort analyses seemed to demonstrate the possibility of success and similar to other observational cohort studies. The results of this study suggest that future randomized control trials evaluating the clinical efficacy of these prothrombin complex concentrates in patients with factor Xa inhibitor related intercranial hemorrhage are needed. Dr Carolyn Lam: Nice, Greg. You know what? I'm going to start with a quiz. True or false, heart failure with reduced ejection fraction is characterized by blunting of the positive relationship between heart rate and left ventricular contractility known as the force frequency relationship? Dr Greg Hundley: Well, Carolyn, this is one of those where if I go 50/50, you'll knock out the wrong answer. Let's say, I'm going to go, true. Dr Carolyn Lam: You're so right, Greg. This next paper really deals with this. It's from corresponding author, Dr Witt from Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds in UK and colleagues who previously described that, tailoring the rate responsive programming of cardiac implantable electronic devices in patients with HFrEF based upon individuals noninvasive force frequency relationship data, really improves exercise capacity. Addressing this reduce force frequency relationship and HFrEF.  Now in the current paper, they sought to examine whether using force frequency relationship data to tailor heart rate response in HFrEF with inpatients, with HFrEF and cardiac implantable electronic devices would favorably influence exercise capacity and left ventricular function six months later. They conducted a single center, double blind, randomized parallel group trial in 83 patients with HFrEF. With a cardiac implantable electronic device and randomized to tailored rate response programming based on these individuals force frequency relationship versus conventional age guided rate response programming. The primary outcome measure was changed in walk time on a treadmill walk test. Dr Greg Hundley: Wow, Carolyn. So this is a really detailed analysis. What did they find? Dr Carolyn Lam: They found that rate adaptive cardiac implantable electronic device programming taking into account the at normal force frequency relationship in these patients, was associated with improved exercise time. Force frequency relationship guided heart rate settings had no adverse effects on left ventricular structure and function. While conventional settings were associated with a reduction in left ventricular ejection fraction. Out of the box age guided rate adaptive pacing, might be a sub optimal choice in patients with heart failure and an assessment of the force frequency relationship might be of clinical benefit in facilitating personalized rate adaptive programming. Dr Greg Hundley: Very nice. Dr Carolyn Lam: Thanks Greg, but there's other stuff I want to tell you about in this issue. There's a research letter by Dr Gambier on Molecular Imaging of Infective Endocarditis with Floral Multiple Trials PET-CT. This is the first time that a Florine 18 PET tracer has been used to specifically image bacterial infection of the heart valves with high sensitivity and specificity in an animal model. Dr Greg Hundley: Oh, good job, Carolyn. Those flooring tracers, very interesting. Another application perhaps. Well, in a perspective piece, I have an article Carolyn from Dr Orly Vardeny from University of Minnesota Medical School in Minneapolis and remembers the prior cardiovascular complications from influenza. And how those experiences may be useful in anticipating some of the cardiovascular complications that we may see from SARS-CoV-2. In a separate article, Dr Aatish Garg and collaborators from VCU Health, present an ECG case of syncope in an individual with severe aortic stenosis status post bioprosthetic aortic valve replacement and coronary artery bypass grassing. Who also has paroxysmal AV block? Then finally, Carolyn, Professor Concepcion Peiró from Universidad Autónoma in Madrid. Has an on my mind pace discusses ACE inhibition and our abuse in relation to the SARS-CoV-2 to virus bonding to ACE two binding sites within the respiratory epithelium. Well, Carolyn, how about we get on to that feature discussion? I can't wait to hear about aortic and mitral valve disease over nearly 30 years. Dr Carolyn Lam: Let's go Greg. Nondramatic valvular heart disease is really common throughout the world. However, no studies have previously estimated their global or national burden, that is until today's feature paper. That's part of the Global Burden of Disease, or GBD, 2017 study. I am so pleased to have with us a corresponding author, Dr Greg Roth from University of Washington. As well as Victoria Delgado, our associate editor from Leighton University Medical Center. What a great topic to discuss. Nondramatic valvular heart disease, meaning calcific aortic valve disease, degenerative module valve disease, all the stuff we see and have to deal with now. Greg, could you please tell us about this GBD effort and really what you found? Dr Greg Roth: Let me tell you a little bit about the Global Burden of Disease Study and then why we wanted to explore this question and then what we found. I am the lead for cardiovascular research at the Institute for Health Metrics and Evaluation in Seattle at the University of Washington. We're the coordinating center for the Global Burden of Disease Study. It's now in its second decade, and it's a large-scale effort to quantify the lost health due to early death and disability for every country in the world. This is a huge effort with over 5,000 people around the world working on it. We work closely with governments around the world, as well as the World Health Organization, as well as county, state, and other authorities in the US. Our goal is really to bring together all of the evidence in the world to bear on important health policy questions. One of the areas that I've had a long interest in is valve disease. I'm a practicing cardiologist at our county hospital here in Seattle, as well as an echocardiographer. I was really excited by the idea of bringing together my passion for taking care of patients with valve disease and looking at how to use diagnostic imaging to take better care of them and the disease modeling research that I do at the institute. We decided a couple of years ago after exploring the global patterns of rheumatic heart disease, that we would turn our focus towards these really important questions of non-rheumatic valve disease. There's obviously a very large literature and lots of active research around the clinical pathways that we need to follow for patients with calcific valve disease and mitral valve disease that's not due to rheumatic causes. Obviously in recent years, we've got amazing technologies and interventions that we're using more and more frequently like percutaneous interventions. However, we had not done the work to turn this really interesting tool, the Global Burden of Disease Study, towards looking at these important causes. We pulled together every data source we could find on the population level burden of nonrheumatic valve disease and then using a range of techniques, and we rely heavily on tools that come out of data science. These include computer disease modeling tools that we've developed as well as ensemble models and other sort of big data approaches to pull all of this together into comparable, consistent estimates of death and prevalence. Then we're also really interested in using those to estimate what we call summary metrics of health, like disability adjusted life years. We do this for a very long time series. So we went back all the way to 1990 and we looked all the way to 2017. Then we're able to get a really good sense of not only what the impact of these diseases are, but how they compare to the 350 other diseases that we estimated in exactly the same way for the Global Burden of Disease Study. Also, where is the burden of these particular conditions going up? Where is it going down? We're really excited to be able to pull that together into this paper. In which we report the global, regional, and national burdens of calcific aortic valve disease and degenerative mitral valve disease. As well as a right sided valve disease that's not due to congenital endocarditis causes, which we estimate separately in the study. Dr Carolyn Lam: Greg, you say, you're excited. I can definitely speak, I think on behalf of both Victoria and Augie, that we're the ones excited publishing this really great piece of work here in circulation. You know personally, I'm a great fan of your work in GBD. Tell us the results. Dr Greg Roth:  What we found was that in 2017, there was an estimated 12.6 million cases of calcific aortic valve disease in the world and 18.1 million cases of degenerative valve disease globally. With higher rates of calcific valve disease, among men and higher rates of degenerative valve disease among women. Now that is an aggregate. We've produced estimates for every country in the world and for larger countries with more than 200 million people, we've gone down to what we call the first administrative level. So, US states, Chinese provinces, and we do this in the larger countries, but when you add it all up, you get those numbers. We also found that there were just over a hundred thousand deaths globally each year due to calcific aortic valve disease and about 35,000 deaths reported due to degenerative mitral valve disease. I think this is really interesting because of course, as clinicians, we have a lot of experience with sources like cohort studies, and trials, and registries, but we have not actually looked at what's actually the world's largest public health reporting system, which is vital registration, meaning death certificates. Now, most of us have filled out that certificates and we always wonder, how reliable are there? And there's clearly limitations. In fact, a huge amount of our work at the Global Burden of Disease Study is dealing with the limitations of death certificates, looking for bias, and adjusting that bias when we can, but these are death certificates where somebody's entered these causes as the underlying cause of death. I think when that actually shows up on a death certificate, that's actually a real signal to us that there was a physician out there who felt pretty strongly that that was the sort of trigger that led to the patient's death. We also found that aging and population growth are leading to about a hundred percent increase over this period of time over the last 25 years in the number of deaths due to these nonrheumatic valve diseases. If we age standardized, we see that the trend is flat, but if you're running a health system or a minister of health, you need to hear that message that with aging and population growth affecting almost every country in the world, you're going to see dramatic rises in the number of cases of both of these conditions showing up on the doorstep of all of your hospitals. Dr Carolyn Lam: Fantastic Victoria, could you put these findings in context for us and maybe take us behind the scenes a little bit at what the editors thought? Dr Victoria Delgado: These are very important data, because so far, for example, we have, as Greg said, registries and one of the most known registries was for example, in Europe, The Valvular Heart Survey that was done in 2001, if I remember well. Has been redone recently, it was last year published in circulation. The other one with a very large data is coming from counties. With similar data to the results that are publishing now. For example, if you compare those two registries with much smaller populations, in US, they always report much, much frequently the genetic mitral valve regurgitation. While in Europe, aortic stenosis is the most frequent one, calcific aortic stenosis. Here, I was again surprised with in the global population that again, degenerative mitral valve regurgitation is much more prevalent than calcific aortic stenosis, but you can see that there was an increase of 124% in the prevalence of calcific aortic valve disease in 2017. I wonder if this is related to the awareness of the risk associated with aortic stenosis and they invent of a new therapies, transcatheter therapies, with the TAVI for example, or transcatheter aortic valve replacement, which has opened the door for an effective treatment for many patients that before were simply denied for surgery. I don't know if you have further insights into that. Dr Greg Roth: Yes. I think that's a really important point, that we see a lot of variation in the data. While we have millions of death certificates to look at all around the world. Really scores of millions, where we can look for trends and patterns. The population level data on nonrheumatic valve disease is actually quite limited compared to most diseases. We did a very aggressive perspective review of the published and gray literature and found about 50 sources reporting prevalence for these conditions that were usable in our study. For the most part, those studies are not long time series. We have to estimate trends, piecing together data from different populations. Now, there are a couple of places in the world where you can get a long trend of time where they've gone back repeatedly in the same population and looked with echo, which you obviously need here to make these diagnoses. As far as we can tell, and these are just a handful of studies, the trend is flat. We don't see large increases. Now, the increases in our study were completely driven by aging and population growth and the age standardized rates. The epidemiologic pattern for this disease is that it's flat and for mitral valve disease, maybe trending down a little bit. I think it's clear that in places where there's been a lot of attention paid either because of new therapies, like TAVR or new access to diagnostic screening with the growth of echo cardiography and other screening methods, that is a limitation of the study, for sure. I think what it really focuses me on is the idea that we need better data. We need to think about ways and probably more cost effective ways of surveilling for these conditions, but I'll tell you something that was really interesting, that we found is that, in the United States where we relied heavily on administratively coded data, because we have that in a uniform format for every state and we have a long time series for that, and we have complete vital registration. We looked at the state level and we found that the all ages rate, was actually going up. Meaning it wasn't just population growth and aging, but in about a third of the states, the true epidemiologic rate of the disease was going up. Meaning it's becoming more common even if you control for the change in age structure of a country like the United States over time. I think that given the fact that we're seeing this explosion of obesity around the world, and we know that atherosclerotic risk factors can be a major driver of let's say calcific aortic valve disease. I mean, an interesting question is, is valve disease going to be sort of a canary in the coal mine? Are we going to see more of it at younger ages? Traditionally it's been the oldest patients who actually survived the longest and tend to be healthier, who we can actually find having the disease, but I wonder, are we going to see more of that as patients present with more obesity. Unfortunately we know that reversing or controlling those atherosclerotic risk factors hasn't paid off in big ways for preventing calcific aortic valve disease. It's complex and like mitral valve disease, clearly there's likely to be a very strong genetic component as well. Dr Carolyn Lam: Greg, you mentioned a little bit more about the age effect, but you did mention some sex differences. Could you just clarify a little bit about that and maybe the interaction between the two? Dr Greg Roth: What we've all been taught, or at least what I was always taught, was that there was more mitral valve disease in women. We actually did find that in the study and that was reassuring because when we went back to look for the source of that sort of common teaching, actually, it's pretty hard to find. I think it actually comes, my guess is, from a lot of people's clinical practice. To see that match-up between what we thought was going to be true in terms of the relative prevalence by sex for these two major diseases, calcific aortic valve disease and degenerative mitral valve disease was reassuring. It suggested that the data we have is actually picking up on real patterns and patterns that match sort of our clinical experience as well. One of the interesting things about the interaction between age and sex, is that women live much longer on average than men. As women age into those oldest years, what we actually see is a decline in the burden of disease. There's an increase in stroke, but for everything else, those women are truly survivors. Actually we see less bowel disease and cardiovascular disease in general, in the oldest old women. What we do see is a massive rise in cognitive impairment and dementia. That's a very active area of research for us right now. The interaction between atherosclerotic risks, which can drive things like valve disease and of course, coronary disease and stroke and then the cognitive impact is a really important area of research. There are a couple of great papers that have come out even just in the last few weeks. I think this question of how risk is going to impact people in those oldest age groups? Is really important. We know the population is aging. We know that in some places, life expectancy is increasing to the point where we really need to rethink what the disease patterns are going to be in the oldest old. Dr Carolyn Lam: Indeed. So the feminization of aging is kind of what I like to call it, but yikes Victoria. Could I maybe ask you to please give the final words of advice and maybe the take home messages? Dr Victoria Delgado: I think that this data are really welcomed because as Greg said, we need to understand better how we can modify the prognosis of these prevalent and how we can tackle it and for that we need data. I think that these are very welcomed data. Now, how we are going to do it in the future? That's a great question. I don't have the answer right now, but I think that increasing the awareness that nonrheumatic valvular heart disease can impact as well on the outcomes of the population, is important to know. I think that people need to have access to diagnostics best particularly echo cardiography is very available imaging technique and very feasible. We can have right now developments where we can do the echo cardiography with our phone by adding one of the probes. I think that in the future, we may see more and more valvular heart disease that probably was already there, but we just need to increase the awareness. From those data, learn how we can treat those individuals if they need and how we can improve the outcome of these individuals. Dr Carolyn Lam: Thank you, Victoria. Thank you, Greg. More awareness and more good data needed. Thank you, audience, for joining us today. You've been listening to Circulation on the Run. Don't forget to tune in again next week. Dr Greg Hundley: This program is copyright the American Heart Association, 2020.  

Heart disease is the number one killer for both men and women. Often, we are told our only answer is medication, more medication…  and to avoid salt. However, if you understand more about why your cardiovascular system is ill, for example if you have some faulty cardiac genes, or a chamber is faulty and causing “nocturnal” hypertension, then you often can fix it. Especially if you work with a doctor that understands the heart from these points of view. Enter center stage. Dr. Mark Houston. Dr. Houston is renowned as the “iconic functional cardiologist” who put functional cardiology on the map. Functional cardiology looks for “root causes” of hypertension and heart disease, such as the specific molecules that create heart damage. The patient is then guided toward making improvements in lifestyle, sleep, blood pressure throughout 24/hours, diet and medications to bring them back to heart health once again. Dr. Houston created the only “functional cardiology certification course” for medical doctors taught at A4M, the Anti-Aging Certification Course.  He teaches all 24-hours himself. Dr. Houston has authored a number of textbooks for cardiologists as well as books for everyday patients. The Hypertension Institute in Nashville, where Dr. Berkson goes for her look-see heart health exams is run by Dr. Houston. Dr. Houston is tripled boarded in hypertension as an American Society of Hypertension (ASH) specialist and Fellow of the American Society of Hypertension (FASH), Internal Medicine (ABIM) and Anti-aging medicine (ABAARM). Nutrition is a subject taken seriously by Dr. Houston. He has a master’s degree in Human Nutrition from the University of Bridgeport, Connecticut and a Master of Science degree in Functional and Metabolic Medicine from the University of South Florida in Tampa. Dr. Houston was an Associate Clinical Professor of Medicine at Vanderbilt University School of Medicine. Dr. Houston has spent his life learning how to figure out the “root cause” of heart disease and high blood pressure and how to individualize natural answers to keep us living longer, healthier and on less medications. In this show you will learn: Differences between blood pressure medications. Which ones do not work very well. Why many patients just don’t get better and what we can do about it. Molecules of mass destruction that “drive” heart disease and how to test and naturally treat these. What is “nocturnal hypertension” and why should your doctor test for this. And more. Dr. Houston and Dr. Berkson are colleagues and both are professors for A4M so this conversation is between friends as well as agile thinkers. You will learn how Dr. Houston’s approach integrates the whole person‚ mind, body and spirit. You will be surprised at the in-depth manner in which his team evaluates the heart, the lining of your blood vessels and even blood pressure analysis. Resources and Links Dr. Houston’s Office in Nashville, TN. Hypertension Institute   Books: What Your Doctor May Not Tell You about Heart Disease   What Your Doctor May Not Tell You About: Hypertension: The Revolutionary Nutrition and Lifestyle Program to Help Fight High Blood Pressure   Nutritional and Integrative Strategies in Cardiovascular Medicine   Podcasts: Functional Cardiology with Mark Houston, MD (#129)

Today's episode of Redefining Medicine spotlights Ines Alfaro, MD. Dra. Inés M. Alfaro-Mendoza graduated from the National Autonomous University of Mexico in 1980. She then completed a year of Social Service in an indigent community, living an experience that marked her life. After completing her Social Service she performed her rotating residency program in Family Medicine at Hospital Metropolitano in Mexico City. In 1989, she moved back to Puerto Rico completing a year of Internship and another year of Public Service as required by the Commonwealth of Puerto Rico.  Dr. Alfaro attended the mini-residency program directed by Dr. Joseph LaDou in Occupational Medicine through Berkeley University in San Francisco.  She dedicated 13 years to the practice of Occupational Medicine, but her life totally changed when in July of 2002 she was diagnosed with a metastatic cancer. Being a conventional physician, she immediately went on to surgery and chemotherapy, but results were poor and prognosis reserved. Determined to live and raise her children, she started seeking other possibilities of treatment, and it is then when she came across Integrative Medicine. She started with Acupuncture, went on to Homeopathy, then Biological Medicine, Neural Therapy, Chelation and then pursued Board Certification in Regenerative and Metabolic Medicine and completed a Fellowship in Integrative Cancer Therapies. At present, Dr. Alfaro is the Medical Director for Alpha Institute of Preventive Care in Caguas, Puerto Rico, focusing her practice on Metabolic Medicine and Integrative Cancer Therapies. She is also a board examiner for A4M.     Dr. Alfaro´s motto in life is:   ¨To Love and to Serve is to Live¨, and that is exactly what she does with her patients.

Dr. Barrett is Board Certified by the American Board of Emergency Medicine, and Board Certified in compliance with the Medical Board of California, business and profession code, section 651. In addition, she specializes in aesthetic, anti-aging and regenerative medicine. She is an Associate Professor at Stanford University Department of Surgery, Division of Emergency Medicine. She is an affiliate Faculty & Clinical Professor for the University of California at Davis, Irvine and San Francisco campus' Hospital. She also trains and acts as a medical advisor and instructor in cosmetic and trauma skin care. Dr. Barrett completed her residency and internship at the University of Southern California, Los Angeles County Medical and Trauma Center. She received her Medical Degree from Michigan State University. Dr. Barrett is a member, fellow, and the examiner for the American Board of Anti-Aging and Regenerative Medicine (ABAARM). She is currently enrolled in the University of Southern Florida as a candidate for her Master's Degree in Metabolic and Nutritional Medicine.   Andrew Jurow, M.D. has specialized in providing unique medical care, built on a solid foundation of integrity, quality and years of medical expertise. His initial training started as an Obstetrician Gynecologist trained at the prestigious University of Southern California, Los Angeles County Medical Center. Dr. Jurow enjoys providing the full practice of Obstetrics and Gynecology. Dr. Jurow served as the Chief of his department of over ten years. Most recently he has received years of additional education and training at the American Academy of Anti-Aging and Regenerative Medicine. In addition he has completed his fellowship in anti-aging medicine and regenerative medicine. He is a current Master's Degree candidate at the University of Southern Florida, Medical School in Nutritional and Metabolic Medicine. Dr. Jurow applies the art of regenerative medicine to his already vast knowledge of natural body balance and hormone use. This has allowed him to restore a natural balance to both his male and female patients. His patients benefit from the use of bio identical hormones, supplements and ongoing adjustments in diet and exercise. This is done only after careful evaluation and applying the principles of evidence based medicine. The detoxifying process and reduction in inflammation caused by our modern lifestyle is considered an integral part of therapy.

What is the best time to eat according to the circadian rhythm? Circadian rhythms are biological rhythms in our body that control all metabolic and physiological processes. When to eat while intermittent fasting? Greg Potter will tell you an answer. Welcome to the Body Mind Empowerment Podcast I'm your host Siim Land. Our guest today is Greg Potter from Human.OS. Greg has a PhD in the Leeds University of Cardiovascular and Metabolic Medicine. His research focuses on circadian rhythms and light-dark cycles. Timestamps: What Are the Circadian Rhythms 03:50 Negative Side Effects of Circadian Disruptions 09:40 Sleep Deprivation VS Circadian Disruption 14:54 Time Restricted Eating 17:00 Eating Early VS Eating Late 27:00 How Long Should You Fast and Eat 35:20 Biggest Disruptors of Sleep 40:01 Sleep Optimization Tactics 46:38 And Much More... Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Link to the YouTube video Download mp3   Use the Code SIIM for a 10% discount on BluBlox Glasses If you want to support this podcast, then I'd greatly appreciate if you could join my Patreon community. You'll be able to get access to unique worksheets about Body Mind Empowerment, a lot of exclusive videos about my routines, biohacking workshops, and a privilege for your questions on the next Q&A.   Click Here to Support the Show on Patreon!    Show Notes Greg Potter's Instagram Join Me and Greg at the Health Optimisation Summit in London Biohacker Summit in Helsinki November 1-2  - Use Code SIIM for a 10% Discount! Metabolic Autophagy Master Class Total Sleep Optimization Video Course Use the Code SIIM for a 10% discount on BluBlox Glasses Last Podcast With Andy Mant on Blue Light Blog Post: How Blue Light Affects Your Body Biohacking Bootcamp in Estonia December 7-9th Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program    Stay Empowered Siim  

Dr. Tarin Forbes received her undergraduate degree from Ohio State University in December of 2000 where she was a captain on the National Championship winning synchronized swim team. She then studied medicine and received her Osteopathic Medical Degree at Midwestern University in Glendale, Arizona in 2006, and completed her residency in Family Medicine at Bayfront Medical Center, St Petersburg, Florida in 2009. To expand upon her advanced medical education after residency, she completed a fellowship and board certification in Anti-Aging and Restorative and Regenerative Medicine, and in Nutritional and Metabolic Medicine through The American Academy of Anti-Aging Medicine (A4M) and the Metabolic Medical Institute in 2016. Recently, she also became board certified in Integrative Medicine from the ABOIM American Board of Integrative Medicine. Dr. Forbes is also a member of Adaptive Cancer Care Essentials Program which is a highly esteemed, prolific and dynamic integrative cancer care training program. Dr. Forbes believes that the best doctors are not only teachers and mentors, but are also leaders that are willing to walk the walk to health and not just advise others to do so. Everything she does is geared towards inspiring patients to live a vibrant life and restoring health using a very personalized medical approach. Her special medical interests lie in optimizing cognitive function and memory, cardiovascular health and fitness, bio-identical hormones and sexual health, and integrative cancer support and prevention. Welcome, Dr. Tarin Forbes! Find out how you can biohack your package with this free eBook: https://hubs.ly/H0ks2Dv0 Website: http://www.themohc.com Instagram: http://www.instagram.com/drtarinforbes Intro Song - https://soundcloud.com/cosimo-fogg/jazzaddicts Outro Song - https://soundcloud.com/ikson/reveal-free-download Follow us! http://www.instagram.com/fatfueledmom http://www.instagram.com/dannyvega.ms http://www.instagram.com/fatfueledkids YouTube http://www.youtube.com/fatfueledfamily Please make sure to SUBSCRIBE and leave us a 5-STAR RATING & REVIEW if you like our content! Please visit our blog: http://www.fatfueled.family PRODUCT CODES and LINKS Amazon Store - http://www.amazon.com/shop/fatfueledmom KetoLogic 10% discount code: FATFUELEDFAM KetoLogic KETO 30: http://bit.ly/2EaqQRG KetoLogic BHB gummies: http://bit.ly/2DhgvkH FBOMB 20% discount code: FATFUELEDFAM FBOMB nut butters: http://bit.ly/2PySREs 1Up Nutrition Supplements: Use code FFM20 for 20% off your order at https://1upnutrition.com Spiral Band Fitness: Use code MAURA to save 10% at https://www.spiralbandfitness.com Pili Nuts: FATFUELEDMOM saves you 10% at http://www.eatpilinuts.com Neuroroast Coffee: KETOCC saves you 10% at http://www.neuroast.com Select CBD: https://bit.ly/2Aesxgy Beautycounter Safe Non-Toxic Beauty Products: http://www.beautycounter.com/mauravega Santa Cruz Medicinals: Save $5 with code fatfueledmom

Josie Bidwell, Associate Professor of Preventive Medicine at the University of Mississippi Medical Center, talks about metabolic medicine with her guests Doctor Honey East and Christy Davis, a nurse practitioner. They also answer questions from listeners. See acast.com/privacy for privacy and opt-out information.

What is the best time to eat according to the circadian rhythm? Circadian rhythms are biological rhythms in our body that control all metabolic and physiological processes. When to eat while intermittent fasting? Greg Potter will tell you an answer. Welcome to the Body Mind Empowerment Podcast I'm your host Siim Land. Our guest today is Greg Potter from Human.OS. Greg has a PhD in the Leeds University of Cardiovascular and Metabolic Medicine. We got to meet at the Biohacker Summit in Toronto and sat down to talk about chronobiology. Timestamps: How the Circadian Rhythms Affect Metabolism 00:24 What is the Best Time to Eat 03:24 Intermittent Fasting and Circadian Rhythms 13:00 Extended Fasting and Circadian Rhythms 21:45 How to Eat for a Healthy Circadian Rhythm 30:00 And Much More... Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Link to the podcast on YouTube Download mp3    Click Here to Watch the Podcast on Video! If you want to support this podcast, then I'd greatly appreciate if you could join my Patreon community. You'll be able to get access to unique worksheets about Body Mind Empowerment, a lot of exclusive videos about my routines, biohacking workshops, and a privilege for your questions on the next Q&A.   Click Here to Support the Show on Patreon!    Show Notes #68 Circadian Rhythms and Sleep Optimization at the Biohacking Bootcamp #65 How Does Fasting Affect the Circadian Rhythms and Living an Epigenetic Afterlife Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program   P.S. The HD video recordings of all the Biohacker Summit Tallinn speeches are now released. Incredible information about optimizing your health and well-being. My own speech talks about doing fasting with training for longevity and muscle growth. Check it out!     Stay Empowered Siim

Welcome to the Mastering Blood Sugar podcast! This is episode one, with Ron Rosedale. Your host is Dr. Brian Mowll, the diabetes coach. He is a certified and master-licensed diabetes educator and IFM certified functional medicine practitioner. Each week, Dr. Brian Mowll will bring you an inspiring health or lifestyle expert to help you learn to boost your metabolism, lose weight, and master your blood sugar with natural, drug-free strategies. Today, Dr. Brian Mowll interviews one of his early mentors in natural diabetes care and reversal — Dr. Ron Rosedale. Dr. Rosedale is an internationally-known expert in nutritional and metabolic medicine, whose work with diabetics is truly groundbreaking. Very few physicians have had such consistent success in helping diabetics to eliminate or reduce their need for insulin and to reduce heart disease — both without drugs or surgery. Dr. Rosedale was the founder of the Rosedale Center and co-founder of the Colorado Center for Metabolic Medicine in Boulder, Colorado, and founder of the Carolina Center for Metabolic Medicine in Asheville, North Carolina. Through these centers, he has helped thousands suffering from so-called incurable diseases to regain their health. One of Dr. Rosedale’s life goals is to wipe out type 2 diabetes in this country as a model for the world. He’s also written a book called The Rosedale Diet that has proven treatment methods for diabetes, cardiovascular health, arthritis, osteoporosis, and other chronic diseases of aging. In this interview today, Dr. Rosedale gives us a better understanding of the hormonal control of blood sugar and metabolism. He explains mTOR and how it relates to aging, cancer, and diabetes. He also teaches how to become better fat-burners and why he would rather have a patient with diabetes than a common cold, as well as his methods to reverse type 2 diabetes. He explains what the ACCORD trial taught us about aggressive diabetes treatment with medications. Dr. Rosedale also explains how we can optimize our genes for optimal health; why a ‘ketogenic’ diet is a terrible name for the low-carb, high-fat diet, and why we shouldn’t chase ketones; and his optimal diet for someone with diabetes or blood sugar problems.  

Dr. Houston is Director of the Hypertension Institute and is tripled boarded in hypertension as an American Society of Hypertension (ASH) specialist and Fellow of the American Society of Hypertension (FASH), Internal Medicine (ABIM) and Anti-aging medicine (ABAARM). He also has a Masters of Science degree in Human Nutrition and is pursuing as Ph.D. in Functional and Metabolic Medicine from the University of South Florida in Tampa. Functional Medicine University: http://bit.ly/2miYA4Q Mark Houston MD: HypertensionInstitute.com Getting more continued education [2:30] CE programs: https://www.a4m.com/ [10:20] Dr. Mark Houston’s book [12:00] Treating your community vs getting the message out [17:40] Dr. Houston’s weight loss strategy [27:50] Obesity and surgical intervention [35:10]

Vaginal mesh, used for the treatment of prolapse and incontinence, has hit the news recently as women pursue litigation after suffering serious complications. But there have been concerns ever since the first type of vaginal mesh was launched in the mid-nineties, only to be withdrawn a few years later. Carl Heneghan, Professor of Evidence Based Medicine at the University of Oxford, explains the 'shambolic' regulation of medical devices, Consultant gynaecologist Swati Jha, who has been collecting data on mesh for over a decade, believes media coverage has been muddled. Women speak of living with surgery, while Inside Health's Dr Margaret McCartney calls for a registry to collect effective data. Plus, new guidance in Scotland challenges the so called 'J-shaped curve' - evidence that moderate drinking is good for the heart. Naveed Sattar, Professor of Metabolic Medicine at the University of Glasgow and part of the committee that produced the updated guidance, talks to Mark Porter about the changes.

In Episode 133 of The Real Food Reel we are joined by Angela Poff, Research Associate from Dom D'Agostino's, Laboratory of Nutritional and Metabolic Medicine. Today we explore the latest research into cancer and the ketogenic diet. Show Notes Angela Poff PhD on Facebook KetoNutrition.org The post RFR 133: The latest research into cancer and the ketogenic diet appeared first on The Wellness Couch.

The Hepatitis B vaccine has been added to the childhood national programme joining the 5 vaccines already given to all young babies at 8, 12 and 16 weeks. Andrew Pollard, Professor of Paediatric Infection & Immunity at the University of Oxford, and Chair of the Joint Committee on Vaccination and Immunisation, explains why. Margaret McCartney and Mark Porter visit men in north London looking for the physical and mental benefits of community sheds. The obesity paradox - can being overweight sometimes be beneficial? Gavin Murphy, British Heart Foundation Professor of Cardiac Surgery at the University of Leicester and Naveed Sattar, Professor of Metabolic Medicine at the University of Glasgow, debate the latest research suggesting that obese people are more likely to survive heart surgery than their slimmer peers. Are clinical trials good for you? We examine the evidence behind conventional wisdom that people taking part in research tend to fare better - whatever their illness.