Podcasts about ph1

Atlassian connected its AI agents to a richer layer of company knowledge (documents, projects, goals, people) and measured a 44% improvement in answer accuracy using 48% fewer resources. Same models. Different information. Brian Armstrong restructured Coinbase the same week: 14% headcount cut, five management layers maximum. When AI can surface what previously required institutional memory and senior tenure, the organizational layers built around that knowledge become harder to justify.The visible shift gets covered in tech headlines. What gets lost in the announcement energy: none of this works if the company hasn't decided what it wants AI to do.The more widespread barrier is upstream of governance. Most executives approving AI budgets are working through the aftermath of pilots that underdelivered, first-generation deployments that didn't survive contact with their actual data, and early model results that left skepticism the current tools have since substantially outrun. That trust deficit — organizations evaluating new AI investment based on experiences two generations old — is where enterprise AI projects most commonly stall. Shadow AI governance and deployment intent are real risks, but they're downstream of that harder problem. There is no closing the capability gap inside an organization that is quietly waiting for the next deployment to fail too.John Willis co-wrote The DevOps Handbook because software teams were shipping code fast without feedback loops or governance. He sees the same pattern repeating with AI — and he spent five decades documenting what happens when the gap between vendor promises and operational reality gets this wide.* Why shadow AI is more dangerous than an outright ban* Why throughput without governance means instability at scale* Why governance creates flow instead of stopping it* Why most teams have ML evaluation tools when they need audit trails* Why even a five-person startup needs digitally signed records of agent decisions* What AI winters teach us about where we actually are nowListen: Spotify | Apple PodcastsRikki Singh leads product innovation at Twilio — what the company calls its biggest launch in 17 years. Before Twilio she was at McKinsey, where she co-authored the definitive research on what makes a great PM. The Qualtrics 2026 CX Trends Report found nearly 1 in 5 consumers who used AI customer service saw zero benefit. That number is the benchmark she is working against.* Why most AI CX is still FAQ automation with better packaging* Why the LLM wrapper creates false confidence — the model generates strings, it is not thinking* Vitamins vs painkillers: how to parse what customers don't say out loud* How to protect long-horizon bets inside a public company* Why the brand owns the accountability when AI gets a high-stakes interaction wrongListen: Spotify | Apple Podcasts

The Stanford AI Index's headline is 88% — organizations using AI in some capacity. The Financial Times charted where it actually lands in the workforce: 62% of top-decile earners use it daily, versus 13% at the bottom. Board decks this quarter will cite Stanford. The FT chart is what they're not showing.The economics that enabled this gap are under pressure. The three-year subsidized era is ending by financial necessity, not choice. The same optimization logic that built social media's loneliness machine is now embedded in AI products at scale. And in the same week Anthropic's most capable model autonomously found 271 zero-days in Firefox, two major platforms were breached through third-party integrations. The data and what to do about it follows.Episode 8: The Most Important Data Points in AI Right NowBrittany Hobbs solo — four segments moving from data to strategic implication. Essential for anyone making AI purchasing, hiring, or architecture decisions right now.The Stanford AI Index 2026. 88% organizational adoption is saturation, not a trend. $581 billion invested globally in 2025, up 129% year over year. The US-China AI performance gap collapsed from 17–31 percentage points in 2023 to 2.7% today — on 23 times less investment. China holds 69.7% of global AI patent filings. Architecture and application discipline closed a gap that capital alone could not. Stanford AI Index 2026 | The U.S. Can't Buy an AI LeadToken economics. Anthropic's current tiers: Haiku at $1/$5 per million input/output tokens, Sonnet at $3/$15, Opus at $5/$25. A 200-screen product built with Claude Design costs $0.22 for a first draft; the 50-iteration refinement cycle real design work requires runs to ~$2,600, plus $200–$900/month in system updates. Every comparable Figma interaction costs zero. Prompt caching provides ~90% discounts on repeated context; batch processing cuts 50%. Claude Design vs Figma cost breakdown | CNBC: Token economicsApple chose its hardware chief as next CEO. John Ternus — SVP of Hardware Engineering, architect of Apple Silicon — succeeds Tim Cook on September 1st. Johny Srouji, who designed every Apple Silicon chip, becomes Chief Hardware Officer. Apple posted $143.8 billion in Q1 FY2026 (up 16%, $109 billion in services, 92% retention) without shipping an industry-leading AI feature. The next decade of AI is decided at the silicon and device level. Apple CEO transition analysisVibe coding has never been more capable. Security has never been more exposed. Anthropic's Mythos model identified 271 zero-day vulnerabilities in Firefox autonomously; the UK's AI Security Institute found it succeeds at expert-level hacking tasks 73% of the time. Anthropic launched Project Glasswing (12 defensive security partners including Amazon, Microsoft, and Apple), then reported unauthorized Mythos access through a vendor. Vercel was breached through Context AI — customer credentials sold on BreachForums for $2 million. Lovable exposed source code and credentials via a basic authorization flaw for 48 days, fixed it, then broke it again for 76 more. TechCrunch: Anthropic Mythos | TechCrunch: Vercel breach | The Next Web: Lovable“If you're making AI decisions for your team right now — what to buy, who to hire, what to build — there are numbers out this week that should change your approach.” — Brittany HobbsListen now: Spotify | Apple Podcasts | YouTube

Let's stop pretending. Most AI strategies are just a collection of pilots that nobody had the courage to kill. The data this period is brutal: 95% of genAI pilots stall. Only 11% reach production in financial services. Microsoft — the biggest company in the world, with the best distribution on the planet — just reorganized Copilot because nobody internally could agree on what it was supposed to be. And while enterprises burn cycles debating governance frameworks, a new class of startups is quietly replacing entire job functions. Not assisting. Replacing. The gap between the people who get this and everyone else isn't a skills gap. It's a courage gap. This edition is about which side you're on.What You'll Learn in This EditionThis edition confronts the uncomfortable reality that most AI investments are producing demos, not outcomes — and the structural reasons why.*

Every influencer is drooling over Claude Code skills files. Every product team is chasing the next model release. But for two years, the data has been screaming the same thing: capability isn't the bottleneck. Context is. This edition unpacks what that actually means — why structured business knowledge is the highest-leverage investment a product team can make, what the “context wars” look like from the inside, and why the teams winning aren't the ones with the best models. They're the ones whose AI actually understands their business.What You'll Learn in This EditionThis edition confronts the structural reason most AI products fail — they're missing the context that makes capability useful.* Why Juan Sequeda from ServiceNow says “hope is not a strategy” — and what to build instead of better prompts* The three-layer knowledge framework that gives AI a shared language across your entire organization* CNBC's “silent failure at scale” investigation reveals why 91% of AI models degrade without anyone noticing* Microsoft just adopted ontology — the same concept Juan has championed for 20 years — as the foundation of its agentic AI architecture* Citadel Securities data shows software engineer job postings rising 11% YoY despite the displacement narrativeEpisode 3: Context Is the New Moat — Why Your AI Needs Business Knowledge, Not Better PromptsEvery influencer is drooling over skills files and prompt templates. Juan Sequeda, Principal Scientist at data.world (acquired by ServiceNow), has spent 20 years proving that none of it works without structured business knowledge underneath. In this episode, Juan breaks down the three-layer framework — business metadata, technical metadata, and the mapping layer that creates real semantics — and explains why the teams investing in ontology today will compound value across every AI use case they build next. His blunt assessment of skills files as a production strategy: “Hope is an interesting strategy. It's not one that I add to my strategy.”“If you just edit in skills, I don't think that's gonna be the solution to your problem. You'll have a great POC. It'll work for the use cases you tested on. Are you willing to put your career on the line and put that in production?” — Juan SequedaListen on Spotify | Apple Podcasts | YouTubeContext isn't a nice-to-have. It's the architecture layer that determines whether your AI product delivers consistent, measurable value or drifts into silent failure. PH1 built this framework to illustrate what Juan Sequeda has been researching for two decades: intent, background, examples, and templates aren't prompt engineering tricks — they're the structural foundation that transforms an AI system from a “forever intern” into a strategic partner. Without them, you're hoping the model figures out what “order” means in your business. Hope, as Juan puts it, is not a strategy.RAG Was the Answer. Now It's a Symptom of the Real Problem.RAG dominated for two years as the default way to give LLMs context. But as context windows expanded from 8K to a million tokens, the question shifted. This video breaks down when RAG still matters — vast, dynamic datasets and cost efficiency — and when long context windows make the retrieval layer unnecessary. The strategic implication for product teams: RAG was always a workaround for a deeper problem. The real question was never “how do I retrieve the right document?” It was “does my system actually understand my business?” That's the context layer Juan Sequeda is building — and it sits beneath RAG, long context, and every other implementation detail.In spite of the displacement signals, software engineer job postings are up 11% year over year. But read the fine print: a posting titled “Software Engineer” increasingly means “engineer who can operate LLMs in production” or “build RAG pipelines.” The title stayed the same — the job changed. If your team hasn't redefined what “engineering” means in the context of AI-augmented workflows, you're hiring for yesterday's role.Product Impact ResourcesThe pattern across these resources is consistent: the teams pulling ahead are the ones investing in context, knowledge, and governance infrastructure — not chasing the next model release. Capability is table stakes. The moat is how deeply your product understands the business it serves.* Gartner predicts 80% of enterprises pursuing AI will use knowledge graphs by 2026 to enhance context and reasoning. The shift from “better prompts” to “structured knowledge” is no longer theoretical. The Role of Knowledge Graphs in Building Agentic AI Systems* Microsoft adopted ontology as the foundation of its agentic AI architecture — Fabric IQ, Foundry IQ, and Work IQ create a semantic layer that gives agents shared business understanding. Microsoft Adopts Ontology-Based IQ Layer for Agentic AI* Nathan Lasnoski argues that enterprise knowledge graphs are the foundation for moving from vibe coding to scalable agentic development — without semantic grounding, agents can't reason across systems. Building an Enterprise Knowledge Graph for the SDLC* HBR analysis reveals AI adoption stalls because of employee anxiety about relevance and identity — not technical limitations. The behavioral barriers are harder than the technical ones. Why AI Adoption Stalls, According to Industry Data* WEF data shows organizations with strong governance and >5% IT budget allocated to AI see 70-75% positive outcomes vs. 50-55% without. Governance is infrastructure, not a bottleneck. Strong AI Governance Is a Business Advantage, Not a Bottleneck* Deloitte's agentic AI strategy report calls for governance and observability as first-class product features — agentic systems should expose provenance, tool-call traces, and policy decisions by default. Agentic AI Strategy* Teresa Torres warns that AI without product discovery just means “shipping the wrong stuff faster.” The line lands directly on this edition's thesis — capability without context is an accelerant of bad decisions, not good ones. Strong potential guest. Shipping the Wrong Stuff Faster * Roger Wong unpacks Jenny Wen's (Anthropic Head of Design) “ship fast, iterate publicly, build trust through speed” approach as a new design paradigm for AI products. Jenny Wen is a compelling guest lead given her role building Claude's product experience. The Design Process Is Dead * Meta's alignment director had an OpenClaw agent start rapidly deleting her inbox — she thought it would confirm first. It didn't. She ran to a Mac mini “like I was defusing a bomb.” Stuart Winter-Tear's breakdown is a vivid, concrete case study of agentic AI failure in practice. Human in the Loop Is a Job * Academic paper in Communications Psychology (Nature) argues that friction in AI design is a feature, not a bug — challenging the default “make it seamless” paradigm. Co-authors from U of T, Wharton, and Yale. Emily Zohar is a strong potential guest with a contrarian take that plays well on the podcast. Against Frictionless AI Product Impact NewsThe news this edition reinforces a single uncomfortable truth: the biggest AI failures aren't technical — they're contextual. Systems that lack business knowledge don't crash dramatically. They drift silently, producing outputs that look right but are wrong in ways no telemetry catches.* CNBC investigated “silent failure at scale” — a beverage manufacturer's AI ordered thousands of excess cans because it couldn't contextualize new holiday labels. 91% of ML models degrade over time, and most enterprises never detect it. ‘Silent Failure at Scale': The AI Risk That Can Tip the Business World Into Disorder* Agentic AI's dominant failure mode isn't catastrophic breakdown — it's silent drift. CIO reports that only 6% of organizations have fully deployed agents, and the Cloud Security Alliance now classifies cognitive degradation as systemic risk. Agentic AI Systems Don't Fail Suddenly — They Drift Over Time* Gartner predicts 40% of agentic AI projects will be scrapped by 2027. 90% of legacy agents fail within weeks. The primary driver is governance, not technology. Why 40% of Agentic AI Projects Will Fail* Internal Microsoft data shows only 30% of Copilot enterprise licenses see weekly active usage after 6 months — despite unmatched distribution through Office. Workflow friction and unclear ROI are the barriers. Microsoft Copilot Adoption Stalls at 30% Active Usage* Virtana surveyed 350+ senior IT leaders this month: 75% of enterprises report double-digit AI job failure rates, a third exceed 25%. Meanwhile, 59% of executives think they're prepared — but 62% of practitioners report fragmented systems and visibility gaps. The disconnect is the risk. 75% of Enterprises Report Double-Digit AI Failure Rates* Citadel Securities rebuts the AI displacement narrative with data: software engineer postings up 11% YoY. But job postings requiring AI literacy grew 70% YoY — the title stayed the same, the job changed. Software Engineer Job Postings Are ‘Rapidly Rising'* Tech Mahindra and Microsoft launched an ontology-driven agentic AI platform for telecoms — the first major enterprise deployment built on Microsoft's Fabric IQ semantic layer. The context wars are real. Tech Mahindra and Microsoft Launch Ontology-Driven Agentic AI PlatformKey takeawaysThe throughline is unmistakable: the AI products failing at scale aren't missing capability — they're missing context. From CNBC's investigation into silent failures to Microsoft betting its entire agentic architecture on ontology, the market is converging on what Juan Sequeda has been saying for 20 years: structured business knowledge is the highest-leverage investment you can make.* Context is infrastructure, not a feature. Skills files and prompt templates are band-aids. The teams compounding value across AI use cases are the ones that defined “what does order mean?” before they shipped anything. If your AI can't disambiguate your business terminology, it can't deliver consistent results.* Governance accelerates adoption. The WEF data is clear: organizations with strong AI governance see 20 percentage points higher positive outcomes. Governance isn't the thing slowing you down — the absence of it is why 40% of agentic projects get scrapped.* The job didn't disappear — it transformed. Software engineer postings are up 11%, but the role now requires AI literacy. The same is true for product managers, designers, and strategists. The question isn't whether AI will replace you. It's whether you'll invest in the context that makes AI actually useful.Check Out Recent EpisodesEpisode 2: Defensibility > Capability — Five Actions to Defend Your Product Value $73.6 billion went into GenAI startups in 2025, but 85% of AI startups will be out of business within three years. This episode tackles the economics of abundance and delivers five specific actions to redirect investment toward what actually survives: workflow depth, outcome visibility, and trust engineering. If you're competing on features, you're already exposed.Episode 1: Why Your AI Metrics Are Lying to You The bullseye framework for AI products — Power, Speed, Impact, and Joy. Most teams are measuring Power and calling it success. This episode introduces a three-layer evaluation approach and shows why completion metrics hide the signals that actually matter for growth.AI Strategy Jobs* Staff Product Designer, AI Workflows — ServiceNow (Remote/Hybrid)* AI Product Manager — ServiceNow (Remote)* Product Designer, ChatGPT — OpenAI (San Francisco)* Product Designer, Platform & Tools — OpenAI (San Francisco)* AI Product Manager, Strategic Roadmap — IDC (Remote)* Principal Product Manager, AI Personalization — Cedar (New York)* Senior Product Designer, Generative AI — Coda (Remote)* Product Designer, AI Agents — Simular (Palo Alto)* Director, Product Design, AI Transformation — Element AI (Santa Clara, CA — On-site, 65% travel)* Product Designer — Fidelity (Merrimack, NH / Jersey City, NJ / Westlake, TX — Hybrid)If your AI product demos well but can't prove it drives value in production, that's a context problem — and it's the gap PH1 closes. We help teams build the measurement and knowledge infrastructure that turns AI capability into measurable business impact. From defining what success means to proving it with data. ph1.caThank you for supporting the Product Impact PodcastEvery episode goes deeper than the headlines to uncover what actually drives AI product success — and what's quietly killing it. If Juan's take on context and ontology challenged how you think about your AI product's foundation, share this episode with your team. Follow the show so you never miss one. That's how we grow this community of builders who refuse to settle for capability without impact.Browse all episodes at productimpactpod.com — filter by topic to find the episode that fits what you're working on right now. We're at 56 episodes across the two seasons. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit productimpactpod.substack.com

AI products are shipping faster than ever. But shipping isn't impact. The teams pulling ahead aren't the ones with the best models — they're the ones who can prove their product moves the business. This edition is about that gap. How to measure what matters, where the biggest barriers to impact are hiding, and what the latest research says about getting AI products to actually drive growth. Because the real competitive advantage isn't AI. It's knowing whether your AI is working.What You'll Learn in This EditionThis edition cuts through the noise to focus on the measurement gap — the difference between shipping AI and proving AI drives growth.* The Power/Speed/Impact/Joy bullseye — a calibration framework for AI products that actually drive growth* A Nature paper reveals why removing friction from AI may be destroying the learning your team needs* John Maeda on why design teams are being hollowed out — and why PMs are next* Benedict Evans on why even OpenAI can't solve product-market fit with capability alone* Research that should change how your team thinks about AI-assisted skill buildingThanks for reading Product Impact | AI Strategy, Value Creation, AI UX! This post is public so feel free to share it.Episode 1: Why Your AI Metrics Are Lying to You - Framework for improving AI product performanceYour AI product might be fast, capable, and technically impressive — and still not drive the growth your business needs. In this episode, Brittany Hobbs and I introduce the Power, Speed, Impact, and Joy bullseye — a calibration framework borrowed from F1 racing. The teams winning aren't shipping more features. They're measuring different things entirely. We break down a three-layer eval approach and why most completion metrics are hiding the signals that matter.“Success does not mean satisfaction. If someone stops engaging, does that mean they solved their problem — or that they were frustrated and left?” — Brittany HobbsListen on Spotify | Apple Podcasts | YouTubeYour Role Isn't Shrinking. It's Being Hollowed Out.John Maeda — Three major tech companies have restructured design teams into “prompt engineering pods.” Maeda's #DesignInTech 2026 calls it what it is: the elimination of design judgment from the product process. “When you replace a designer with a prompt, you don't lose the pixels. You lose the questions that should have been asked before anyone opened a tool.” This applies to product managers too — if your PM's job becomes prompt-wrangling instead of deciding what to build and why, you've automated the wrong layer. The roles aren't disappearing. The judgment inside them is.Featured Resource: Strategy for Measuring & Improving AI ProductsThe gap between what AI products ship and what they prove is where growth stalls. This framework moves teams from tracking activity — token counts, completion rates, session length — to defining and measuring the outcomes that actually drive business impact. Most teams ship features and assume engagement means success. It doesn't. If your team can't answer “is this AI feature making the business better?” with data, you're flying blind. The framework covers product discovery through scale, with concrete steps for building measurement into your AI product from the start — not bolting it on after launch.Read the full resource at ph1.caWaterfall: we'll build you a car in 18 months. Agile: here's a skateboard, we'll iterate. AI: here's a photorealistic render of a Lamborghini that doesn't start. We've never made it easier to build something that looks incredible and does absolutely nothing. AI development doesn't need more iteration — it needs someone asking “does this thing actually drive?”If your team is celebrating demos instead of outcomes, you're already behind the teams that measure first and ship second.Two years of capability gains. Almost no reliability improvement. This is the chart that should be on every product team's wall — because it explains why your AI demos brilliantly and fails in production. Capability without reliability isn't a product. It's a liability.If your team can't name which type of AI they're building, they can't measure whether it's working. Six categories that force precision. — Narain JashanmalProduct Impact ResourcesThe resources in this edition make one thing clear: the teams investing in measurement and deliberate friction are pulling ahead, while the ones chasing capability are stalling. These resources challenge the assumption that faster and more capable automatically means better outcomes.* Removing struggle from AI workflows destroys the learning that builds expertise. Teams should audit which friction to keep and which to cut. Against Frictionless AI — Inzlicht & Bloom in Nature* AI users learned 17% less without any efficiency gains. How your team uses AI matters more than whether they use it. How AI Impacts Skill Formation — Shen & Tamkin RCT* Two years of capability gains with only modest reliability improvement. The barrier to growth isn't what models can do — it's whether you can trust them. The Capability-Reliability Gap — Narayanan et al.* Polished AI outputs reduce critical evaluation by users. Build in friction points that force your team to think before accepting. (Anthropic studying its own product — read accordingly.) Anthropic AI Fluency Index* AI forces strategic clarity because you cannot delegate logic you haven't articulated. That's a feature, not a bug. Strategy as Protocol — Schwarzmann via Scaman* Six functional AI categories that sharpen how teams talk about what they're building. Precision in language is precision in product decisions. AI Taxonomy — Jashanmal* Mapping 50 AI startups across six pricing models reveals that pricing is a product decision, not a finance one. Get it wrong and adoption stalls regardless of quality. How to Price AI Products — Gupta* Wade Foster shut Zapier down for a week-long AI hackathon. Adoption went from 10% to 50% in five days. Adoption follows experience, not mandates. Zapier's Code Red HackathonProduct Impact NewsThis is the news that matters. Reliability failures are making headlines, benchmark credibility is collapsing, and even the market leaders can't prove product-market fit. The gap between what AI can do and what it can prove is widening, not closing.* ChatGPT missed diabetic ketoacidosis and respiratory failure in 52% of emergency cases. Suicide-risk alerts fired inconsistently. Reliability is the product, not a feature to ship later. ChatGPT Health Under-Triaged 52% of Emergencies* LLMs chose nuclear strikes in 95% of simulated crises. The nuclear taboo is no impediment to AI escalation — a stark reminder that evaluation stakes extend beyond product. AI Models Chose Nuclear Strikes in 95% of Simulated Crises* Google patent US12536233B1 lets it generate its own landing page from your product feed if yours scores below threshold. Own your experience or someone else will. Google Patented AI Landing Pages That Replace Your Storefront* 84% of the world has never used AI. Only 0.3% pay for it. The growth opportunity is massive — but only for teams that solve adoption, not just access. 84% of the World Has Never Used AI* 80% of ChatGPT users sent fewer than 1,000 messages in 2025. Even the market leader hasn't solved product-market fit. Capability alone isn't enough. OpenAI Has No Moat and Engagement an Inch Deep* RCT shows AI tools made experienced developers work faster and take on broader tasks — without measurable output gains. Speed is not productivity. METR: Experienced Devs Saw Zero Productivity Gain* NIST finds standard benchmarks conflate different performance measures. Models with different scores may perform identically in production. Build your own evals. NIST: AI Benchmarks Don't Measure What They Claim* MIT reviewed 300+ AI implementations: 85% failed, 91% of models degrade silently. The 5% that succeeded built measurement into the product from day one. 85% of AI Projects Fail, 91% of Models Degrade SilentlyKey takeawaysThe throughline across this edition is unmistakable: capability without measurement is theater. From the METR study showing zero productivity gains for experienced developers to MIT's finding that 85% of AI projects fail, the evidence converges on one point — the teams that win are the ones that prove their AI works.* Measure outcomes, not activity. Completion rates, token counts, and session length tell you your AI is running — not that it's working. Define what “working” means for your business before you ship.* Protect judgment. Automate everything else. The roles being hollowed out aren't the ones doing rote work — they're the ones asking the hard questions. If you're automating decisions instead of tasks, you're cutting the wrong layer.* Friction is a feature. Research consistently shows that removing struggle from AI workflows destroys learning and degrades skill. Build in the friction that keeps your team sharp, and strip out the friction that just wastes time.If your AI product ships well but you can't prove it drives growth, that's the gap PH1 closes. We help teams define what success looks like for AI experiences and build the measurement systems to prove it — from product discovery through scale. ph1.caThank you for supporting the Product Impact PodcastEvery episode tackles the gap between what AI products promise and what they actually deliver. Brittany and I bring in the builders, researchers, and leaders who are closing that gap — with frameworks, evidence, and hard-won lessons. If an episode shifted how you think about your product, share it. Follow the show so you never miss one. That's how we grow this community.* Episode 1: Why Your AI Metrics Are Lying to You* Vibe Coding Will Disrupt Product — Base44's Path to $80M* AI Trap: Hard Truths About the Job MarketBrowse all episodes at productimpactpod.com — filter by topic to find the episode that fits what you're working on right now. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit productimpactpod.substack.com

In this special bonus episode Talking General Practice speaks to consultant nephrologist Dr Shafi Malik about the heightened risk of genetic kidney conditions among South Asian populations.In this conversation, Dr Malik explains why patients of South Asian origin are more at risk of genetic kidney disease and how common these conditions are. He talks specifically about primary hyperoxaluria type 1 (PH1), the symptoms patients might present with if they have this condition - including recurrent kidney stones - and, as kidney stones are a common presentation, how healthcare professionals can recognise when these cases may warrant further investigation.This episode was presented by GPonline editor Emma Bower. It was produced by Czarina Deen.This episode of Talking General Practice has been funded by Alnylam Pharmaceuticals and produced in collaboration with GPonline. It is intended for UK healthcare professionals only.Useful linksThinkPH1.euNational Kidney Federation – PH1About Alnylam PharmaceuticalsAlnylam is a leading biopharmaceutical company and the pioneer in RNA interference (RNAi), a revolutionary approach to treating diseases which “silences” the genes that cause or contribute to them. Founded in 2002 by a group of distinguished researchers and biotech leaders, Alnylam has translated the Nobel Prize-winning science of RNAi into an innovative class of medicines, with the belief that the RNAi approach to treating disease has the potential to help people around the world live longer, healthier and more fulfilling lives. Hosted on Acast. See acast.com/privacy for more information.

Yvonne An is a Korean entrepreneur and creator based in Manila. She blends creativity with data, even building her own TikTok analysis bot to study trends, performance, and what drives PR and brand deals. Yvonne shares an honest look into her life—balancing startups, mental health, and her experience living in the Philippines—making her a relatable voice for Gen Z builders and creatives.Connect with Yvonne:https://www.instagram.com/yvonnean_https://www.tiktok.com/@yvonnneCHAPTERS:0:00 – Introduction0:49 – Meet Yvonne1:15 – What Yvonne has been focused on2:21 – Why Yvonne started a company5:12 – Content creation as stress relief5:59 – What she enjoys about creating7:38 – Building a TikTok data bot9:27 – How the bot measures content ROI10:44 – How she built the bot11:58 – Labeling & scraping TikTok data12:51 – Tracking growth and plateaus14:11 – Why she signed with an agency15:27 – Balancing startups + content16:28 – Her dad's surprising hobbies16:56 – Yvonne on her mom & family19:11 – Where her independent energy comes from20:24 – Gen Z entrepreneurs21:59 – Thoughts on Cluely's content strategy23:45 – Young entrepreneurs today24:09 – Her brother's path24:40 – Would she want kids?25:17 – Raising entrepreneurial kids27:15 – How parents shape business mindset28:51 – Lessons from her dad's hardships32:09 – When her dad left LG33:48 – How old she was then34:46 – Andy's first trip to the Philippines36:37 – Rockwell run club38:42 – Filipino “clientele relationship”41:58 – Building company culture in PH45:53 – Antidepressants & mental health47:57 – Impulsive behavior in relationships48:33 – Andy's personality quiz (money)50:11 – Is religion good or bad?52:14 – Emotional vs. logical54:01 – Who's more hardworking?54:12 – Wait for someone or date who likes you?54:39 – Her biggest 2024–2025 takeaways55:55 – Naming a child with two letters56:40 – What she'd change about Andy57:37 – Airport ride scenario59:12 – Last time she asked for help1:04:18 – Last three times she helped others1:07:45 – Andy's reflection on Yvonne1:09:45 – Guessing each other's MBTI1:16:00 – Similar vs. opposite partners1:16:49 – Does she have ADHD?1:17:06 – Feeling out of place in PH1:19:35 – Her day-to-day life in Manila1:20:43 – Balancing career + relationship1:22:02 – Purpose of life1:23:19 – Is life meaningless?1:23:51 – What puts her in a sad state1:24:43 – How convo would differ without SSRIs1:25:35 – Does she need SSRIs long-term?1:26:49 – Her anxiety1:27:49 – Plans for the rest of her gap year1:29:10 – Could she thrive at UC Berkeley?1:30:40 – Being seen as a “pretty dumb girl”1:32:07 – Story about people “playing dumb”1:34:40 – Yvonne's recent life discoveries1:35:26 – Her next 6-month goal1:36:42 – Why Andy thought her life was “nerfed”1:38:58 – Connect with Yvonne1:40:14 – Why some girls “play dumb”1:41:13 – How her personal brand shows only a slice of her1:42:21 – Outro

We're back! After a bit of a hiatus, your hosts return with a discussion of the mystical, magical pH1 barrel that has shaped many American sour beer programs. Also, a recap of the Weldwerks Invitational beer festival and a white whale wild ale tasting you won't want to miss. Cheers!Beer Tasting:Fuzzy, Side Project Brewing, St. Louis, MO. Style: Wild ale with Peaches

Alex sources a line-up of four mostly from Colorado West Coast IPAs that have never been featured on the show to see who reigns supreme in the Centennial State! Alex also gives an update about Facebook drama after the Barleywine is Life group gets deleted. In the Beer News, Stephen and Alex try to Blue Moon lip balm, the famed PH1 barrel is now full of Off Color beer as John Laffler reveals what's gestating inside everyone's favorite barrel, New Belgium releases a set of Malort IPAs but the gimmick raises some red flags, mostly stolen valor, and William H. Macy does a whiskey collab that no one asked for. To get involved with the  "Life" International Barleywine Collab, click the link for info about the recipe, BSG discount, and links to help raise awareness of colon cancer.  If you'd like to make a direct donation to help support Alex, head over to his GoFundMe.  For more info about colon cancer and to help support the fight against it check out the Colon Cancer Foundation.  Head to our Patreon for weekly exclusive content. Get the Malt Couture Officially Licensed T-shirt. Follow DontDrinkBeer on Instagram and Twitter.

Grabs your clubs, we're cracking NA beers and putting up bogeys! Alex and Stephen try a wholesome foursome of NA beers from Resident Culture Brewing, Fieldwork Brewing Co., Burial Beer Co., and Golden Road Brewing. Alex reveals he knows nothing about the world of fine art. In the Beer News, PH1 lands in the hands of John Laffler at Off Color Brewing which is very exciting news if you were old enough to drive a car when 9/11 happened, Goose Island Bourbon County Brand Stout will make their 10oz bottle debut this year, and Campari enters the RTD NA cocktail game.  To get involved with the  "Life" International Barleywine Collab, click the link for info about the recipe, BSG discount, and links to help raise awareness of colon cancer.  If you'd like to make a direct donation to help support Alex, head over to his GoFundMe.  For more info about colon cancer and to help support the fight against it check out the Colon Cancer Foundation.  Head to our Patreon for weekly exclusive content. Get the Malt Couture Officially Licensed T-shirt. Follow DontDrinkBeer on Instagram and Twitter.

ONE OR EIGHT caught up with Rob Herrera via ZOOM for an interview behind the creative process for new single “KAWASAKI” featuring Big Sean and PH1.Thank you for listening! If you enjoyed and learned something from this podcast please be sure to follow and rate it in order to help us grow in the podcast space.You are also welcome to help support this podcast with a small monthly donation to help sustain future episodes.If you'd like to watch my video interviews, I invite you to Subscribe to my channels at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.YouTube.com/FrontRowLiveEnt⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ & ⁠⁠⁠www.Youtube.com/Punkvideosrock⁠⁠⁠ Follow Us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@FrontRowLiveEnt⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ | ⁠⁠⁠@Punkvideosrock⁠⁠⁠ |⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@Robertherrera3⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠#oneoreight #FrontRowLiveEnt

ONE OR EIGHT caught up with Rob Herrera via ZOOM for an interview behind the creative process for new single “KAWASAKI” featuring Big Sean and PH1.Thank you for listening! If you enjoyed and learned something from this podcast please be sure to follow and rate it in order to help us grow in the podcast space.You are also welcome to help support this podcast with a small monthly donation to help sustain future episodes.If you'd like to watch my video interviews, I invite you to Subscribe to my channels at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.YouTube.com/FrontRowLiveEnt⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ & ⁠⁠⁠www.Youtube.com/Punkvideosrock⁠⁠⁠ Follow Us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@FrontRowLiveEnt⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ | ⁠⁠⁠@Punkvideosrock⁠⁠⁠ |⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@Robertherrera3⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠#oneoreight #FrontRowLiveEnt

On Tuesday, Oct. 29 at 3 p.m. a QTBIPOC Healing and Wellness Workshop will be held in PH1-230 to discuss the importance of wellness and healing as a QTBIPOC individual. From Oct. 28 through Oct. 31, Veterans Services will be hosting Halloween Movie Week from 8 a.m. to 5 p.m. in the Veterans Services Office. Veterans Services will also be hosting Spooky Bowling on Oct. 29 from 4 p.m. to 6 p.m. Last Friday, Oct. 18 the Department of Cinematic Arts Chair, Adam Moore, stepped down. David Waldman, the department's associate chair, will step in as the interim chair in Moore's absence. On Halloween day starting at 4 p.m. is trick-or-treat on 2nd Street, a local event for families and locals to take part in innocent Halloween activity.   Get in the Halloween spirit at The Queen Mary's Dark Harbor experience and enjoy the last week of the attraction from Oct. 29 to Nov. 2. Tickets range from $50-$70 on varying days and the event includes rides, mazes, food and drinks.  The city of Long Beach is set to receive more than $6.8 million in federal funding from the Department of Homeland Security's Federal Emergency Management's Port Security Grant Program. This funding will be used to upgrade the port's infrastructure and make advancements in its security. As of Friday, Oct. 25, an E. Coli outbreak in McDonald's Quarter Pounders has caused at least 49 people to get sick and killed one person across 10 different states. The Centers for Disease Control and Prevention released a food safety alert on Tuesday after they established a common thread between those affected was the Quarter Pounder. All who got sick tested positive for E. Coli. Last month, Kentucky Senator Johnnie Turner was mowing his lawn when he fell into an empty swimming pool while riding the mower. The senator sustained undisclosed injuries and passed away last Tuesday. U.S. Defense Secretary Lloyd Austin confirmed in a conference last Wednesday that North Korea has sent 3,000 troops to Russia to aid in their war effort. The government of South Korea also stated that North Korea has promised to deliver 10,000 troops to Russia in the coming months.  Off the southern coast of Mexico, Hurricane Kristy has formed but has no current trajectory to hit land. The tropical storm upgraded to a Category 3 storm on Wednesday. As of Friday, Oct. 25, there have been no weather warnings in places as the hurricane continues to travel east into the Pacific Ocean. Host & Editor: Gianna Echeverria Producers: El Nicklin, Aidan Swanepoel Like, comment, and follow us on your favorite platform for more content! Apple Podcasts https://podcasts.apple.com/us/podcast/long-beach-current-podcasts/id1488484518 Spotify ⁠https://open.spotify.com/show/4HJaqJep02kHeIQy8op1n1⁠ ⁠⁠⁠Overcast https://overcast.fm/itunes1488484518/long-beach-current-podcasts

El menú de hoy es PITAPA y Smoothie en tamaño XXL. #MúsicaEntreChingus  En este episodio de [K-Music Café] te platicamos sobre las novedades musicales coreanas, todo lo que hemos visto y escuchado desde el pasado episodio no. 31, hasta hoy: celebramos los 20 años de dos dúos dinámicos, te presentamos raperos del bolsillo de Patt y te compartimos los rookies de kpop que adoptamos este mes.Acompáñanos en el chismecito musical y cuéntanos cuál fue tu MV, canción o comeback favorito de este “mes”. *Síguenos en redes sociales:Instagram: https://www.instagram.com/entrechingusTwitter: https://twitter.com/entre_chingusTiktok: https://www.tiktok.com/@entrechingus Hoy hablamos de:· DAY6 - Fourever [Mini álbum]· UNIS - We unis [Mini álbum]· Young Posse - XXL [Single]· Leni. M - Lost things [Single]· BANG YONG GUK - 3 [Álbum]· Dynamicduo - 2 Kids on the block [Álbum]· J-Hope - HOPE ON THE STREET VOL. 1[EP]· PEPPERTONES - Twenty Plenty [Álbum]· twlv - Diminished [Álbum]· NIve - Zz [Single]· Churry - 잘 지내지 못할 거야 [Single]· Rolling Quartz - Stand up [Single]· Juniel - 안녕 Bye [Single]· DPR Cream - Savage [Single]· LUCAS - Renegade [Single]· TXT - minisode 3: Tomorrow [Mini álbum]· ONEWE - Planet Nine: ISOTROPY [Mini álbum]· NCT DREAM - DREAM()SCAPE [Mini álbum]· ILLIT- Super Real Me [Mini álbum]· SUPER JUNIOR D&E - 606 [Mini álbum]· The New Six - Fuego [Single]· NOWADAYS - Nowadays [Single álbum]· Lee Mu Jin - Propose [Single]· Lay Zhang - Psychic [Single]· Jinjin & Moonbin - Fly [Single]

Desangradas y debiendo hasta el aire que respiramos, pero ¡lo logramos!Este episodio es para rememorar, reflexionar y ¡hacer cuentas! pues terminaron los conciertos coreanos del 2023 y te compartimos el resumen ejecutivo de lo vivido en ellos; cuántos hubo, gastos que hicimos y críticas de siempre, para que te ayude a prevenir lo que nos depara el futuro en materia de conciertos.Júzganos o empatiza con nosotras chingu, eres libre, pero esperamos que lo principal siempre sea compartir consejos y tips para poder disfrutar de la mejor manera la experiencia en un concierto de música coreana.Recuerda también recurrir a nuestros episodios anteriores sobre conciertos: 32, 38 y 46 para más “información que cura”.No olvides contarnos tus experiencias en conciertos o dudas no resueltas. ¡Este es tu espacio chingu!*Síguenos en redes sociales:Instagram: https://www.instagram.com/entrechingus Twitter: https://twitter.com/entre_chingusTiktok: https://www.tiktok.com/@entrechingus

Check out our free downloads at nascentmc.com: Implementing AMA Style – 8 Things to Get Right in Your Next Project Needs Assessments – 7 Essentials for Getting Funded Working With Your Medical Writer – 8 Ways to Get the Most out of Them See the full write ups for today's episode at nascentmc.com/podcast Here are the highlights:  Novavax COVID Vaccine:The updated Novavax COVID-19 vaccine is approved for use in the US for those 12 and older and is a conventional vaccine containing purified, full-length recombinant Spike (rS) protein. This rS protein stimulates the immune system to generate a protective immune response, specifically by eliciting antibodies against the Spike protein of the SARS-CoV-2 virus.  Rivfloza (Nedosiran) for Primary Hyperoxaluria:The FDA approved Rivfloza, an RNA interference therapy, to treat primary hyperoxaluria type 1 (PH1) patients by lowering urinary oxalate levels. The medication will be available for eligible patients in 2024. Intravenous Cosentyx:The FDA approved an intravenous (IV) version of Cosentyx for treating adults with certain rheumatic diseases, making it the only approved IV treatment that targets interleukin-17A (IL-17A). It will be available in Q4 of 2023. Abrilada Adalimumab Biosimilar:Abrilada has been designated as interchangeable with adalimumab, meaning it can be substituted at the pharmacy level without notifying the prescribing provider. It was proven to provide similar outcomes to the reference product even when patients switched between them multiple times. Injector for Empaveli in PNH:The FDA approved the enFuse® Injector for delivering Empaveli to adults with paroxysmal nocturnal hemoglobinuria (PNH). This device is the first purely mechanical, large-volume subcutaneous drug delivery device, and Enable Injections is collaborating with other manufacturers for its application. Intro and outro music Garden Of Love by Pk jazz Collective

¡Star makers, reúnanse! ✦Te habíamos contado anteriormente acerca de los shows de supervivencia de kpop y su funcionamiento, pero en este episodio tenemos un ejemplo claro del cual chismear, fangirlear y criticar: BOYS PLANET. Acompáñanos a conocer y desmenuzar este programa de principio a fin, a pasar corajes por los resultados o por las controversias, y a platicar con nuestro chingu Juan acerca de los chicos que, a nuestro ojos, brillaban más.- Cuéntanos qué te pareció el episodio, cuál hubiera sido tu top 9 a debutar o si quieres más episodios de reviews de shows coreanos.*Síguenos en nuestras redes sociales para  mantenerte al pendiente de nuestros episodios y  conocer el resto de contenido que compartimos:Instagram: https://www.instagram.com/entrechingus/Twitter: https://twitter.com/entre_chingus

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.17.532993v1?rss=1 Authors: Draeger, T. N., Rey, M.-D., Hayta, S., Smedley, M., Alabdullah, A.-K., Moore, G., Martin, A. C. Abstract: Tetraploid and hexaploid wheat have multiple genomes, with successful meiosis and preservation of fertility relying on synapsis and crossover only taking place between homologous chromosomes. In hexaploid wheat, the major meiotic gene TaZIP4-B2 (Ph1) on chromosome 5B, promotes crossover between homologous chromosomes, whilst suppressing crossover between homeologous (related) chromosomes. Tetraploid wheat has three ZIP4 copies: TtZIP4-A1 on chromosome 3A, TtZIP4-B1 on 3B and TtZIP4-B2 on 5B. Previous studies showed that ZIP4 mutations eliminate approximately 85% of crossovers, consistent with loss of the class I crossover pathway. Here, we show that disruption of two ZIP4 gene copies in Ttzip4-A1B1 double mutants, results in a 76-78% reduction in crossovers when compared to wild-type plants. Moreover, when all three copies are disrupted in Ttzip4-A1B1B2 triple mutants, crossover is reduced by over 95%, suggesting that the TtZIP4-B2 copy is also affecting class II crossovers. This implies that, in wheat, the class I and class II crossover pathways may be interlinked. When ZIP4 duplicated and diverged from chromosome 3B on wheat polyploidization, the new 5B copy, TaZIP4-B2, may have acquired an additional function to stabilize both crossover pathways. In plants deficient in all three ZIP4 copies, synapsis is delayed and does not complete, consistent with our previous studies in hexaploid wheat, when a similar delay in synapsis was observed in a 59.3Mb deletion mutant, ph1b, encompassing the TaZIP4-B2 gene on chromosome 5B. These findings confirm the requirement of ZIP4-B2 for efficient synapsis, and suggest that TtZIP4 genes have a stronger effect on synapsis than previously described in Arabidopsis and rice. Thus, ZIP4-B2 accounts for the two major phenotypes reported for Ph1, promotion of homologous synapsis and suppression of homeologous crossover. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

TRAGEDY OF THE SOLOMONIC ERA As in the case of Israel's possession of the land in Joshua, (PH1-10 after the Northern & Southern Campaign effectively eliminated the 31 kings) so toward the end of narrating the zenith of Israelite kingship in Solomon, 1 Kings 8:56 says that Solomon's reign and building of the temple happened "according to all that He promised; not one word ... failed of all His good promise, which He promised through Moses His servant." “You will bring them in and plant them in the mountain of your inheritance, in the place you made for your residence, (Palace) O Lord, the sanctuary, (Temple) O Lord, that your hands have established.” Exodus‬ ‭15:17‬ ‭ This is not mere fulfillment of prophecies about a kingdom and a temple; in the light of the links to Gen. 1-2, this is also the realization of a kingdom and a temple in what appeared to be an emerging new creation (X2M-99-). And, as with Joshua, although there was an escalated fulfillment of prophecies of the Israelite kingship and of the temple (and even more so with Solomon), these fulfillments were not consummated. Subsequent history reveals this lack of consummation in that sin by both Solomon and Israel occurred, resulting not in elevation of conditions into a new creation (X2M99-) where perfect righteousness dwells but rather in the deleterious consequences of the splintering of Israelite kingship and kingdom, destruction of the temple, and dismantling of the nation itself in exile. Also, both Moses's prophecy in Exod. 15:17-18 and God's promise in 2 Sam. 7:10-16 (an allusive development itself of the Exod. 15 passage) affirm that the kingdom and the temple will be established forever, which did not happen with Solomon. Lack of complete fulfillment is indicated also by the conditional way that the fulfillment is expressed (1 Kings 2:4; 8:25; 9:1-9)… “and the Lord will fulfill his promise to me, ‘If your descendants watch their step and live faithfully in my presence with all their heart and being, then,' he promised, ‘you will not fail to have a successor on the throne of Israel.'” ‭1 Kings‬ ‭2:4‬ ‭NET‬‬ …as well as by the observation, as in Joshua, that left in Israel were some of the people remaining from the enemy nations,"whom the sons of Israel were unable to destroy utterly" (1 Kings 9:21). THE WHY OF ZECHARIAH - see notes in book The essence is the restoration | Tikkun and consummation | Olam of God's kingdom. SIX DAYS Invitation Initiation Designation Probation Conferral Confirmation SEVENTH DAY Consummation The consummation which would have been typified in Solomon was only completed in Jesus that the fullness of Christ would be in us in this end-time generation by transfiguration leading to glorification... “After Solomon finished building the Lord's temple, the royal palace, and all the other construction projects he had planned, the Lord appeared to Solomon a second time… Jesus fulfills the complete conditions of the covenant with one sacrifice Beginning next week, X2M-114 we will start with the book of Zechariah detailing through 7 visions/aspects of our King of Glory… X. Introduction to Structure 1. Governor of the Nations 2. Avenger of the Afflicted 3. Builder of God's City 4. Guardian of God's Courts 5. Anointer of God's Temple 6. Desolator of the Apostates 7. Judge of the World Much of the church usually camps out around 1, 2 or a few of the above 7 attributes of Jesus…we need a robust multifaceted view of Him in consummation….that He's the Governor, Avenger, Builder, Guardian, Anointer, Desolator of the apostates, Judge…the King of Glory! Our aperture of Him will not then be 1, 2 or few sides but multifaceted and our vision will be reality in our midst within and without as Collider comes into fruition. That even as we behold (vision) Him in His consummation…the consummation of the ages we will become like Him.

C'EST L'HEURE DE LA BIBLE EXPLIQUÉE DANS UNE ANNÉE.PH1:1-30 HHH is a non-profit organization bringing the gospel of Jesus to the people of Haiti through building churches, educating everyone, and championing families. Our goal is to create a group of people that love Jesus, love one another, love to tell other people about Jesus, and are empowered to use their skills to glorify Jesus! MERCI POUR VOTRE SUPPORT. HAITIAN HELPING HANDS P.O.BOX 4564 LYNCHBURG VIRGINIA 24502 MOMENT AVEC FRÈRE WILFRID HAITIAN HELPING HANDS P.O.BOX 4564 --- Support this podcast: https://anchor.fm/haitianhelpinghands/support

C'EST L'HEURE DE LA BIBLE EXPLIQUÉE DANS UNE ANNÉE.PH1:1-30 HHH is a non-profit organization bringing the gospel of Jesus to the people of Haiti through building churches, educating everyone, and championing families. Our goal is to create a group of people that love Jesus, love one another, love to tell other people about Jesus, and are empowered to use their skills to glorify Jesus! MERCI POUR VOTRE SUPPORT. HAITIAN HELPING HANDS P.O.BOX 4564 LYNCHBURG VIRGINIA 24502 MOMENT AVEC FRÈRE WILFRID HAITIAN HELPING HANDS P.O.BOX 4564 --- Support this podcast: https://anchor.fm/haitianhelpinghands/support

Tyler and Matt discuss the AUR along with the latest Linux News and our Thingies of the Week.  Video Version; https://youtu.be/7-9DE9pTlTs ===== Thanks to Our Patrons! ==== Tier 7 - Tux Level - Patrons Robert M. Tier 5 Patrons Syd A. Tier 5 Devon, Patrick, Fred, Kramer K., Tri-Devil Tier 4 Patrons Antoine, Unkle Bonehead, KB, Griffs Lounge Tier 3 Patrons Maeglin, Jackson Knife and Tool, Steve A, CyberGuyLinux, Garrick, Samuel, TGB, Keith,  Andy P., Gary A., Ross  Tier 2 Patrons Mitchel, Joris AKA JDawg, carbondated, Shaun, Jeremy, Odin, Martin, Eduardo S., archsinner, Elliott F., Mislav Tier 1 Patrons Marek, Camp514, Joshua Lee, Peter, Crucible, Darkbadits6,  Primus, PM, rlocone, Phillip ===== Follow us

Dr. Kimberly Durant (e-mail) of Leadbetter Rehabilitation and Dr. Meghan Musick (e-mail, LinkedIn, Twitter, Instagram) of Jefferson Physical Therapy are interviewed by Antigone Vesci regarding a presentation they gave at the 2021 AAOMPT Conference titled, “Fourth Trimester and Beyond - Where is the Treatment? What is the Evidence?” This episode contains information that will be interesting for practitioners who want to learn more about pelvic health as it relates to orthopaedic clinical practice and the postpartum population. Additionally, to find the resources mentioned during this interview use the following links: Podschun et al  2013 (the hamstring/pelvic floor case study), McArthur et al 2016 (urinary incontinence does not go away), Moore et al 2021 (BJSM and JOSPT systematic review about factors contributing to return to running), Dakic et al 2021 (effect of pelvic floor symptoms on women's participation in exercise), Cozen Screening Tool (for pelvic floor dysfunction), AAOMPT Pelvic Health Special Interest Group's Decision Tree, Brown et al 2006 (3 question incontinence screening tool), Talasz et al 2011 (phase-locked parallel movement of diaphragm and pelvic floor during breathing and coughing), the American College of Obstetricians and Gynecologists (ACOG) recommendation for postpartum exercise, Donnelly et al 2020 (return to running), Cassidy et al 2017 (Canadian pelvic health survey), Julie Wiebe courses (including external only techniques), Antony Lo (Physio detective), Evidence in Motion's Pelvic Health I course, Kelli Wilson of Alcove Education, Tough to Treat Podcast by Susan Clinton and Erica Meloe, Herman & Wallace Pelvic Floor Level 1 (internal course), and APTA Pelvic Health Pelvic Health Physical Therapy (Level 1 or PH1 is an internal course). Listeners may also find the BJSM Return to Running Blog to be useful.Find out more about the American Academy of Orthopaedic Manual Physical Therapists at the following links:Academy website: www.aaompt.orgTwitter: @AAOMPTFacebook: https://www.facebook.com/aaompt/Instagram: https://www.instagram.com/officialaaompt/?hl=enPodcast e-mail: aaomptpodcast@gmail.comPodcast website: https://aaomptpodcast.simplecast.fm

BTS become Louis Vuitton ambassadors, ITZY got the NYAFG headquarters divided, and we're back in the ENHYPEN universe to discuss their latest album, BORDER : CARNIVAL! Listen as we discuss what happened in the KPOP world this past week!Tune in every Tuesday for a new episode and don't forget to follow our social media and let us know what you think.Time stamps:1:34 - D-CRUNCH2:03 - Cignature3:34 - B.O.Y5:42 - Running Man6:29 - Mark Tuan6:50 - MIRAE fandom name9:12 - BTS Butter12:35 - BTS Louis Vuitton ambassadors 16:04 - Sarah Barrios & Eric Nam - Have We Met Before?19:37 - eAeon & RM - Don’t23:35 - HOT ISSUE - GRATATA30:08 - ONF - Ugly Dance32:43 - AB6IX - CLOSE37:11 - pH1 ft. Jamie - 365&739:18 - (G)I-DLE - Last Dance41:25 - ITZY - In the Morning44:55 - ENHYPEN - BORDER:CARNIVAL Album Review45:32 - Intro : The Invitation48:04 - Drunk-Dazed57:13 - FEVER1:02:31 - Not For Sale1:06:03 - Mixed Up1:08:40 - Outro : The Wormhole1:12:40 - Songs of the WeekListen here!Apple: https://podcasts.apple.com/us/podcast/not-your-average-fangirls/id1397623744iHeartRadio: https://www.iheart.com/podcast/269-not-your-average-fangirls-30301805/Google Play: https://play.google.com/music/m/Io43vmfj25ycw543oknngnnnnra?t=Not_Your_Average_FangirlsSpotify: https://open.spotify.com/show/4OL4qPjUyRsjfX30FIDczsThis week's playlist: https://open.spotify.com/playlist/0GxfVlZnMSN8t42Rz36D36?si=7d5595c8aef24177www.twitter.com/NYAFangirlswww.twitter.com/HollaItsCarowww.twitter.com/heyitsteeteewww.twitter.com/deekaydiwww.twitter.com/HollaItsCynwww.notyouraveragefangirls.com

Aujourd'hui, on se demande pourquoi on a arrêté d'écouter de la folk, Clément aimerait qu'on en finisse avec les sirènes sonores dans les morceaux et Louise approuve le message du titre de Yaya Bey. Retrouve-nous sur Instagram et Twitter @lesondapres.Les morceaux présentés :Local Natives - Who Know Who CaresAudrey Nuna - damn RightYaya Bey - Fxck it thenFlex Fab & Ziller Bas - Haya Wee! Autres références :Playlist LE SON D'APRÈS dispo sur Apple Music, Spotify, Deezer & YouTube !Si vous nous trouvez pas, liens ici : https://linktr.ee/lesondapresLOCAL NATIVESSaint DXL'album Gorilla ManorLe morceau Who Know Who CaresL'album HummingbirdPhoxGrizzly BearsFleet FoxesVampire WeekendLes InrocksL'album « Veckatimest » de Grizzly BearsL'album « Fleet Foxes » de Fleet Foxes AUDREY NUNANoga Erez - End Of The RoadLe label Roc NationAudrey Nuna - SpaceLe magazine HypebaeLe magazine HypebeastLes articles « Baewatch » sur des artistes fémininesDJ SnakeLes titres : Paper, « Time » et « Long Night »Le label H1GHERCha Cha MaloneJay ParkLe track « Last Song » de Jay Park, PH1 et Audrey NunaLes mixtapes : « Blue Tape » et « Red Tape »Anwar Sawyer, son producteurYAYA BEYNinja TunesBig Dada RecordsL'album Madison TapesL'EP « The Things I Can't Take With Me »Les morceaux « September 13th » et « Industry Love » Amy WinehouseLe premier album de Amy Winehouse « Frank » FLEX FAB x ZILLER BASLe collectif FleeMugogo! part. 1 et part. 2Magugu (cf. épisode 12 du podcast)Le documentaire « Mugogo! Rising » sur la chaîne YouTube de Ziller BasBandcampVHOOR (cf. épisode 10 du podcast)Ange Violent, l'illustrateur qui a bossé sur la pochetteLe podcast « Faya » de Nique La Radio Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

The FDA Group's CEO, Nick Capman, sits down with Ben Locwin, Senior Consultant for Public Health Outreach at the CDC, and Executive Advisor for Valeocon Management Consulting, to discuss what life science leaders should expect from the FDA in 2021 as it pertains to quality system management, regulatory approvals, GxP compliance, and more. Ben has extensive experience working with the FDA and international regulatory officials. His project work includes Pre-IND, NDA, Ph1-3, and marketed/post-market drug products, as well as PMA and 510(k) medical devices. Ben has trained FDA inspectors within their headquarters and has participated in the design of the FDA's Global Quality Metrics Initiative. Need RA/QA/Clinical project or resourcing support? The FDA Group helps thousands of life science organizations rapidly access the industry's best consultants, contractors, and candidates. Our resources assist in every stage of the product lifecycle, from clinical development to commercialization, with a focus in Quality Assurance, Regulatory Affairs, and Clinical Operations. Learn more and get the conversation started: www.thefdagroup.com.

While lovers and well-wishers are out and about eating dinner on Valentine's day evening, Nimer and I, Warren are busy recording episode 23 of the "ANTAD" podcast.In this episode, we put the focus on the happenings of the week--From the Samsung unpack of the Galaxy S20 series, to the cancellation of MWC, the merger of Sprint and T-Mobile and most importantly, the departure of a hero, from which this episode's title is derived!We say goodbye to, perhaps the best Android phone ever built--The Essential PH1 phone as the curtains got drawn this week on both the company--Essential and the PH1.The PH1 won't see any security updates again and the last it saw is the Feb. 5th security patch.Thus, we a sad heart, we say goodbye to a hero.Towards the end of the episode, I, Warren demonstrated an app called "Let go"--a buying and selling app, just like eBay, except that this has a focus on one's locale."Let go" can be found at the following Play URL:https://play.google.com/store/apps/details?id=com.abtnprojects.ambatanaNimer demonstrated Google Feed as well as the "Commentary" screen Reader and we closed with plugging in the second installment of the "Commentary" demonstration by Aaron Spears.We welcome your questions and concerns by contacting us via email at:antadpodcast@gmail.comTo join the "ANTAD" mailing list, then simply send a "join request" to:antad+subscribe@googlegroups.comShould you want to subscribe to the podcast through Google Play music, then hit the URL below:https://bit.ly/2Pbrnb1--- Send in a voice message: https://anchor.fm/anatadpodcast/messageSupport the show (https://www.pod.fan/blind-tech-guys)★ Support this podcast ★

▬▬▬▬▬▬▬▬ PLAN DE CE PODCAST ▬▬▬▬▬▬▬▬4:19 Actu semaine Mon séjour à Paris Société de consommation Synthèse du documentaire "nourrir son cerveau" que vous pouvez voir ici :https://ormevert.com/arte-alimentation-cerveau29:45 Quel âge as-tu ?30:45 Oeufs36:47 Légumes et oméga 338:42 Viande crue42:20 Trempage des noix46:05 Trouver de la viande nourrie à l'herbe46:50 Pommes de terre50:14 Eaux minérales & digestion53:42 Bio-électronique de Vincent56:52 Cuisson58:55 Être enceinte et fumer1:00:55 Vitamines, températures et pH1:01:52 Amandes1:03:20 Pistaches1:04:10 Filtres à eau Brita1:06:00 Oméga 31:07:45 Faire bouillir l'eau1:08:45 Oléagineux en excès1:09:45 Bain et bicarbonate1:10:26 Sportifs et protéines1:13:42 Formules alcalinisantes1:18:33 Respiration1:20:25 Wim Hof1:22:25 Chocolat noir1:23:17 Massages1:24:25 Tests urine / Physioscan1:25:28 Signes extérieurs d'acidose1:27:25 Psyllium et Bernard Clavière1:28:33 Orme Vert1:28:45 Augmenter le taux de HCl (acide chlorhydrique) de l'estomac1:31:07 Temps nécessaire pour changer son terrain1:32:14 Apnée1:32:37 Stress1:32:55 Respiration en milieu pollué1:33:28 Soja1:34:54 Sucre1:34:57 Exposition au soleil1:35:24 Cohérence cardiaque1:35:36 Soja (la suite)1:36:03 Bains dérivatifs ou alcalins ▬▬▬▬▬▬▬▬▬▬▬▬▬▬ COMMENT ME SUIVRE ▬▬▬▬▬▬▬▬▬▬▬▬▬▬1. Retrouvez-moi sur mon site Web ici : http://ormevert.com/blog2. Abonnez-vous à la chaîne Youtube ici : http://ormevert.com/aboyoutube3. Likez ma page Facebook ici : http://ormevert.com/facebook4. Retrouvez-moi sur INSTAGRAM : http://ormevert.com/instagram5. Ecoutez-moi sur mon PODCAST : http://ormevert.com/podcast

From the beginning men have sought to make their mark in this world, in this episode you will enter into the foray of the masculine developmental process. In this episode Carroll will take you through the following categories: PH1-6 Product PH7 Service PH8 Stereotype PH9 Prototype PH10 Archetype PH11 Clastronaut ...And from there launch into an apology for monarchy, tell the story that moves from a prayer at a stump to a root that is rising ushering in the millenial reign of Christ! Resources for you to engage with: The Art of Manliness - Three Archetypes https://www.artofmanliness.com/articles/3-archetypes-of-american-manliness-part-i-the-genteel-patriarch/ Stereotype, Prototype and Archetype https://www.dailywritingtips.com/archetype-vs-prototype/ An Apology for Monarchy https://docs.google.com/document/d/13ByP0nE8pI5WxIA-NxLVg6qc1J5F2b8d0MYt-CrEmAw Tree Stump Prayer - Billy Graham https://billygraham.org/story/the-tree-stump-prayer-where-billy-graham-overcame-doubt/ The Preacher and the Presidents: Billy Graham in the White House https://amzn.to/2KoW1eP The Nazarene https://weekly.israelbiblecenter.com/a-branch-from-david/ Nazarene Roots: Pastors, Prophets, Revivalists & Reformers https://amzn.to/2GR47e7 Riseroot & The change of Priesthood Numbers 24:17 2 Chronicles 6:41 Psalms 3:7 Psalms 68:1 Psalms 132:8 Zechariah 6:12 Hebrews 7:11,14 To schedule with the Chrysalis Lab staff, questions/solutions and get involved email us at info@oomz.org and/or Partner at paypal.me/MZHOP

***Explicit*** On this final truncated episode of Boat Fright we explore the government's experiments into finding the elusive brown note on Can't Figure It Out. Then, on the last (for now) Dracula: A Look Backula he tells us about his shelved movie Dracula House. Brought to you by PH1

***Explicit*** This week the Boat Fighters open up the end of Summer Camp Fights With Boat where they conduct a three-legged race. Then they tune into PH1 for Action Nixon! And finally, Flo and the Cheeseburgler lay into incel Brian Somethingsomething on Lover's Lament. Brought to you by Regretzels Pretzels.

***Explicit*** This week Boat Fight features a segment from PH1's hit show After The Money's Gone with a very special guest. After that, they do more Spotitries But Fails with Eric's cool stuff playlist. Brought to you by the upcoming film The Mariner.

**This episode was recorded on October 6th. I'm sorry :(** In this episode, Josh and Stephen are on vacation together in Japan. Consider donating to us on Patreon (http://www.patreon.com/thisweekinkpop) or Paypal (http://paypal.me/thisweekinkpop). Music Videos of the Episode: (05:10) Wanna One - Energetic (15:40) SVT Leaders - Change Up (25:35) Sunmi - Gashina (35:15) Sik-k, Ph1, Jay Park - Iffy (45:55) Jay Park, Boi B, Double K - Reborn (50:30) G.Soul - Can't (56:00) Nick&Sammy - Belong To Me (1:02:10) Henry - That One (1:06:30) Jisook & Ilhoon - Baesisi (1:11:35) 10cm - Phonecert Big Names, No Games (1:19:05) Weki Meki - I Don't Like Your Girlfriend (1:28:25) EXO - Power (1:40:55) Gfriend - Summer Rain (1:49:10) BTS - DNA Consider Donating: Patreon (http://www.patreon.com/thisweekinkpop) Paypal (http://paypal.me/thisweekinkpop) Audible (http://www.audibletrial.com/twik) Fun Stuff: Youtube (http://www.youtube.com/thisweekinkpop) Twitter (@thisweekinkpop, @twikstephen, @twikjosh) Instagram (@thisweekinkpop) Soundcloud (http://www.soundcloud.com/thisweekinkpop) Email (thisweekinkpop@gmail.com) Our Website (http://www.thisweekinkpop.com) Essential Kpop (http://www.essentialkpop.com)

With Gareth Myles and Gavin Fabiani-Laymond  RSS Link: http://mobiletechaddicts.libsyn.com/rss iTunes Stitcher Tunein   Show Notes Listener feedback: hi Gareth, I remember you saying on the podcast your wife was running with the soundpeats q16, does she still recommend them? Glynn   News: F-Secure Sense  - Interview with Harry Killander Andy Rubin’s Essential phone in a nutshell WWDC Rumours Play Test: Gareth   Acer Swift 1 Review A Look At The BenQ W1090 1080P Projector – A Video Unboxing Honor 8 Pro Review – The best value smartphone Gavin Honor 8 Pro - Awesome Camera Shots Insta360 Air and Insta360 Nano - 360 reviews Asus Zenfone 3 Zoom Review - Optical Zoom plus 5,000mAh battery Samsung Galaxy S8 review - plus camera showcase Bargain Basement: Lenovo Miix 310 Tablet with Detachable Keyboard, Intel Atom, 4GB RAM, 64GB eMMC, 10.1" Touch Screen Microsoft Surface Pro 4 with Keyboard Cover and Surface Pen Main Show URL: http://www.techaddicts.uk Email: contact@techaddicts.uk Twitter: @techaddictsuk ; @garethmyles ; @gavinfabiani  ; @GadgetyNewsCom ; @JayGarrett ; @swanny ; @girlsngadgets ; @wildlime Facebook: Tech Addicts Web: http://gavinsgadgets.com ; http://GadgetyNews.com ; http://swanny.me/ Google Plus: +Techaddicts; +garethmyles ; +gavinfabiani-laymond; +JayGarrett  

Oxford Sparks presents a journey around the planets. Find out more and read about the science behind the animation at www.oxfordsparks.net/planet.

The effect of a synthetically produced pheromone (PAP) on the well-being of pigs during transport to the slaughter house Even though numerous attempts to reduce stress during the transport of slaughter pigs, the losses due to transportation induced stress are between 0.03% and 0.5% in the EU and 0.4% in Germany. PSE is seen in 10 to 20% of the animals. A naturally occurring pheromone is secreted by the mammary glands of the sow, which have a calming and stress reducing effect on the piglets as well as on adult pigs. In this placebo controlled double blind study, the possible stress and aggression reducing potential of the synthetically produced `Porcine Appeasing Pheromone (PAP)´ (SSNA Sanofi Santé Nutrition Animale) was examined in slaughter pigs during their transport to the slaughter house and the possibility of improved meat quality. Eleven groups, each containing 24 pigs (n=264 Pigs; Breed Pi x DL) weighing 102 ± 10.6 kg were observed. Each group was transported in a livestock trailer, traveling the same route with the same driver for 40 to 45 minutes from the finishing barn to the slaughterhouse. Before and after the pigs were transported, a number of parameters were recorded. For the experiment, 6 ml of the PAP was sprayed along the back of the neck in five of the groups (n=150 pigs) while in the other six groups (n=144 pigs) a placebo was applied the same way. The cortisol level in the saliva of the live animals was determined in eight animals of each group (1. base level at the finishing barn, 2. after transport, 3. 30 minutes after arriving at the slaughter house in a holding pen). The animals‘ behavior was also observed using video surveillance in the holding pen for 25 minutes (scan sampling every 30 seconds). The heart rates of eight animals per group were recorded using a Polar® sport tester; the surface body temperature was measured using infrared thermography and the animals were weighed. Post mortem, the pH1 and pH24, the ability to conduct in the ham and in the chops were determined and the carcasses were examined for injuries due to fighting. In addition, the air humidity and ambient air temperature on the outside and inside of the livestock trailer was measured. The results show a definite stress- or transport-induced activation of the Hypothalamic-hypophyseal-adrenal axis (HPA) in all animals. A significant increase of the cortisol levels were evident in the saliva samples taken from all the pigs after transport versus the base level samples taken in the finishing barn. The animals treated with the pheromone had a significantly lower saliva cortisol concentration (p=0.02) compared to the pigs who were given the placebo (placebo 22.55 ± 6,4 nmol/l, pheromone 19,15 ± 7,26 nmol/l). Analyzing the heart rates revealed no significant difference between the two groups. The highest heart rates were reached during loading (170 - 173 bpm) and the rate slowly decreased to 118 - 120 bpm while in the holding pen. The severe strain the animals are under becomes evident when one looks at the high heart rates. The body temperature taken at the base of the ear also showed no significant difference between the control and PAP group. The base temperature, although dependent on the ambient air temperature and weather conditions, remained steady in its increase during transport on cold or warm days (4.5 ± 2.5 °C on cold and 4.6 ± 1.9 °C on warm days). Even the parameters weight loss and behavior showed no differences between the PAP group and the control group. The carcasses had few minor injuries, which were evenly spread between both groups. This can be attributed to the fact that the groups were transported individually by pens without mixing unfamiliar animals. On the other hand, the measurement pertaining to the quality of the meat did show a possible influence by the application of the PAP. The pH1 in the longissimus dorsi muscle of the pheromone treated pigs is significantly higher 45 minutes after slaughter (p