Podcasts about life health

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

– The episode opens with a short introduction from Donald Trump praising “one of the most successful business leaders… Michael Dell” and his “really exciting announcement.” – Brett Butt follows with a nostalgic anecdote about growing up before the Internet and World Wide Web, and remembering early video games like Pac-Man, Asteroids, Wizard of War, Scrambled, and Defender. He jokes about wishing for something people now have. – Mike Dell then introduces himself (“Like Dell's World… That's me”) and frames the episode as covering two major topics: technology (how tech works and is used) and personal updates. He notes customer service issues he'd complained about previously have not improved. – Personal updates: – He reports attending multiple recent funerals: mentions having been to “three funerals in the last six months, or two,” and that he's about to go to another in Detroit that weekend. – He names specific losses: Todd Cochran, founder of Blubrry, who passed “late summer, early fall”; his wife's best friend Mary in Grand Haven, who died of lung problems and was younger than them; and his uncle Bill Busby, who turned eighty-eight at a recent party, helped start Motorola Semiconductors, was a US Air Force veteran (crew chief on a B-57 or B-58), and then passed away Monday morning. He says he and his nearly 98–99-year-old grandmother will be traveling to Detroit for that funeral. – Health update: Mike had a torn retina in his right eye, underwent emergency surgery, had to be face-down post-op while a bubble/oil was placed in the eye. At his second post-op checkup the doctor said things are looking good; vision in that eye is blurred by the oil bubble while the other eye is 20/20. He expects the oil to be removed and vision to clear later. He says this grounds him for about six weeks. – He mentions a lingering low-level cold over the past month. – Recent events and work: – He attended Military Creator Con in Arlington, Texas (several hundred participants, veterans/active military/spouses), where he saw Jamie Jay, Christopher Lochhead, Gordon Firemark (podcast lawyer), and others. The event ran long days and was busy but enjoyable. – At Blubrry he's been promoted to VP of Operations, overseeing teams and day-to-day work; Barry (another cofounder) is now CEO. He encourages podcasters to contact him for help, states he uses Blubrry hosting and the PowerPress plugin, and plugs Blubrry's services. – Technology and AI: – He discusses AI-generated content broadly: YouTube's proliferation of AI-narrated slideshow-style or AI-generated videos; his guilty pleasure of “AI Karen stories” on YouTube (which he knows are AI and mostly fiction). – He references a MacRumors article reporting YouTube will automatically label AI videos even if creators don't, and applauds the move, predicting many viewers will prefer non-AI content when labeled. – He raises concerns about AI in podcasting: AI-voiced podcasts and companies generating massive amounts of AI podcast content. He names a company, Inception PointAI, that reportedly generated a lot of AI podcast content and moved from Spreaker to Megaphone/Spotify; he says such AI content can hallucinate and produce factually untrue information, and that some AI podcasts present content as true. – He describes his own measured use of AI: he uses AI for transcripts and some artwork that he then tweaks, and he tried a cloned AI voice for one episode a few years ago but it didn't sound right. He notes telltale patterns of AI-written scripts and advises never to ask AI for its opinion. – He touches on scams: modern scam emails are harder to spot because language models clean up grammar; he warns about requests for immediate payment, iTunes/gift cards, or crypto as signs of scams. – Advertising and social media observations: – Criticizes YouTube mid-roll ads that interrupt videos, and the perceived decline in value of TV ads—locally seeing many online gambling ads in Michigan. – Observes AI activity on Facebook: AI agents entering groups to start conversations (sometimes inane or provocative) and AI-generated video shorts (e.g., airplanes doing impossible things). He dislikes Facebook's prompts to read more on Threads and says he doesn't want more social media accounts. He mentions being on LinkedIn, using X a little, and participating on Reddit, and says he plans to use a flip phone when he retires. YouTube Will Now Automatically Label AI Videos Even When Creators Don’t – Podcasting industry and advice: – Clarifies his use of “podcast” to mean generally audio (though he acknowledges podcasts can be video) and emphasizes that podcasting is a distribution method open to anyone. – Contrasts highly produced, broadcast-style podcasts (teams of producers and sound designers) with indie, authentic podcasts (one person talking into a microphone from a shed). He values indie authenticity and accessibility. – References a report by Tom Webster of Sounds Profitable noting people seek authentic-sounding podcast audio. He warns the industry is bifurcating between highly produced shows and indie creators. – Gives practical advice: podcasting is inexpensive and accessible (buy a microphone, record, compress to MP3, upload to hosting or WordPress to create an RSS feed). Suggests inexpensive cover art via Fiverr and mentions Blubrry hosting around fifteen dollars. Warns that podcasting generally won't replace a day job quickly—monetization takes time and consistency. – Lists three elements for podcast success: consistency, authenticity, and having content that is interesting/informative/compelling (he stumbles on phrasing but leaves the point authentic). He notes technology barriers are lower now; you don't have to be a geek. – Explains distribution parity: small indie shows can sit beside big shows like Joe Rogan in directories; one can succeed without becoming huge. His personal goal is to have a place to speak freely rather than chase large monetization. – Plans and format changes: – He says they will restart the Podcast Insider show with a revamped, more conversational format with two or three hosts discussing industry trends (e.g., trend toward video). – Discusses video: video has always been part of podcasting but is getting more prominent; video production is harder (lighting, appearance, editing). Blubrry is working on a video product to better support creators. – Mentions his short-form series “Cup of Traverse City” (daily, five minutes) which he took a month off from and tried to restart; he intends for it to be five days a week, five minutes, when resumed. – Reiterates he podcasts when it's fun and will take breaks when needed. – Closing: – He notes he has been talking for forty-five minutes, asks listeners if they're still subscribed and what they think about technology trends (is tech “going off the deep end” or is he being a curmudgeon?), invites feedback via email (mike at mike dell dot com), and signs off saying “Catch me later.”

– The episode opens with a short introduction from Donald Trump praising “one of the most successful business leaders… Michael Dell” and his “really exciting announcement.” – Brett Butt follows with a nostalgic anecdote about growing up before the Internet and World Wide Web, and remembering early video games like Pac-Man, Asteroids, Wizard of War, Scrambled, and Defender. He jokes about wishing for something people now have. – Mike Dell then introduces himself (“Like Dell's World… That's me”) and frames the episode as covering two major topics: technology (how tech works and is used) and personal updates. He notes customer service issues he'd complained about previously have not improved. – Personal updates: – He reports attending multiple recent funerals: mentions having been to “three funerals in the last six months, or two,” and that he's about to go to another in Detroit that weekend. – He names specific losses: Todd Cochran, founder of Blubrry, who passed “late summer, early fall”; his wife's best friend Mary in Grand Haven, who died of lung problems and was younger than them; and his uncle Bill Busby, who turned eighty-eight at a recent party, helped start Motorola Semiconductors, was a US Air Force veteran (crew chief on a B-57 or B-58), and then passed away Monday morning. He says he and his nearly 98–99-year-old grandmother will be traveling to Detroit for that funeral. – Health update: Mike had a torn retina in his right eye, underwent emergency surgery, had to be face-down post-op while a bubble/oil was placed in the eye. At his second post-op checkup the doctor said things are looking good; vision in that eye is blurred by the oil bubble while the other eye is 20/20. He expects the oil to be removed and vision to clear later. He says this grounds him for about six weeks. – He mentions a lingering low-level cold over the past month. – Recent events and work: – He attended Military Creator Con in Arlington, Texas (several hundred participants, veterans/active military/spouses), where he saw Jamie Jay, Christopher Lochhead, Gordon Firemark (podcast lawyer), and others. The event ran long days and was busy but enjoyable. – At Blubrry he's been promoted to VP of Operations, overseeing teams and day-to-day work; Barry (another cofounder) is now CEO. He encourages podcasters to contact him for help, states he uses Blubrry hosting and the PowerPress plugin, and plugs Blubrry's services. – Technology and AI: – He discusses AI-generated content broadly: YouTube's proliferation of AI-narrated slideshow-style or AI-generated videos; his guilty pleasure of “AI Karen stories” on YouTube (which he knows are AI and mostly fiction). – He references a MacRumors article reporting YouTube will automatically label AI videos even if creators don't, and applauds the move, predicting many viewers will prefer non-AI content when labeled. – He raises concerns about AI in podcasting: AI-voiced podcasts and companies generating massive amounts of AI podcast content. He names a company, Inception PointAI, that reportedly generated a lot of AI podcast content and moved from Spreaker to Megaphone/Spotify; he says such AI content can hallucinate and produce factually untrue information, and that some AI podcasts present content as true. – He describes his own measured use of AI: he uses AI for transcripts and some artwork that he then tweaks, and he tried a cloned AI voice for one episode a few years ago but it didn't sound right. He notes telltale patterns of AI-written scripts and advises never to ask AI for its opinion. – He touches on scams: modern scam emails are harder to spot because language models clean up grammar; he warns about requests for immediate payment, iTunes/gift cards, or crypto as signs of scams. – Advertising and social media observations: – Criticizes YouTube mid-roll ads that interrupt videos, and the perceived decline in value of TV ads—locally seeing many online gambling ads in Michigan. – Observes AI activity on Facebook: AI agents entering groups to start conversations (sometimes inane or provocative) and AI-generated video shorts (e.g., airplanes doing impossible things). He dislikes Facebook's prompts to read more on Threads and says he doesn't want more social media accounts. He mentions being on LinkedIn, using X a little, and participating on Reddit, and says he plans to use a flip phone when he retires. YouTube Will Now Automatically Label AI Videos Even When Creators Don’t – Podcasting industry and advice: – Clarifies his use of “podcast” to mean generally audio (though he acknowledges podcasts can be video) and emphasizes that podcasting is a distribution method open to anyone. – Contrasts highly produced, broadcast-style podcasts (teams of producers and sound designers) with indie, authentic podcasts (one person talking into a microphone from a shed). He values indie authenticity and accessibility. – References a report by Tom Webster of Sounds Profitable noting people seek authentic-sounding podcast audio. He warns the industry is bifurcating between highly produced shows and indie creators. – Gives practical advice: podcasting is inexpensive and accessible (buy a microphone, record, compress to MP3, upload to hosting or WordPress to create an RSS feed). Suggests inexpensive cover art via Fiverr and mentions Blubrry hosting around fifteen dollars. Warns that podcasting generally won't replace a day job quickly—monetization takes time and consistency. – Lists three elements for podcast success: consistency, authenticity, and having content that is interesting/informative/compelling (he stumbles on phrasing but leaves the point authentic). He notes technology barriers are lower now; you don't have to be a geek. – Explains distribution parity: small indie shows can sit beside big shows like Joe Rogan in directories; one can succeed without becoming huge. His personal goal is to have a place to speak freely rather than chase large monetization. – Plans and format changes: – He says they will restart the Podcast Insider show with a revamped, more conversational format with two or three hosts discussing industry trends (e.g., trend toward video). – Discusses video: video has always been part of podcasting but is getting more prominent; video production is harder (lighting, appearance, editing). Blubrry is working on a video product to better support creators. – Mentions his short-form series “Cup of Traverse City” (daily, five minutes) which he took a month off from and tried to restart; he intends for it to be five days a week, five minutes, when resumed. – Reiterates he podcasts when it's fun and will take breaks when needed. – Closing: – He notes he has been talking for forty-five minutes, asks listeners if they're still subscribed and what they think about technology trends (is tech “going off the deep end” or is he being a curmudgeon?), invites feedback via email (mike at mike dell dot com), and signs off saying “Catch me later.”

Joseph Roethel, director, AM Best, discusses two Best's Special Reports that found no catastrophe-driven P/C impairments following three years of elevated storm losses, while recent health impairments include a number of troubled affiliates.

I didn't plan on talking about this on the show… but you can't fake perspective after a day in the ER. In this episode, I share a scary moment—morning long chest pain—that sent me to the hospital and forced me to ask some hard questions about stress, health, and what really matters. Then Londa and I pivot into real estate and break down the costly mistakes buyers keep making, like: Scheduling movers on closing day Waiting too long to switch utilities Underestimating repair and maintenance costs If you care about protecting both your health and your home, this conversation is for you.

Alison Martin shares how employee wellbeing, AI adoption, and having a system of measurement for organizational wellbeing support a resilient workforce. Hosted on Acast. See acast.com/privacy for more information.

Biohacking expert Gary Brecka spent 22 years predicting people's deaths for life insurance companies. While analyzing millions of medical records, he discovered that many health problems stemmed from preventable nutrient deficiencies and poor oxygen management rather than genetics. Yet he was legally forbidden from warning the people behind the data. Frustrated by the system, he walked away from the industry and dedicated his life to helping people reclaim their health. In this episode, Gary shares powerful biohacking and wellness strategies to boost energy, improve brain health, and add years to your life through simple daily habits. In this episode, Hala and Gary will discuss:  (00:00) Introduction (02:12) Predicting Death in the Insurance Industry (07:06) Gary's Early Fascination with Human Biology (13:51) Hidden Nutrient Deficiencies Causing Illnesses (24:13) How Nutrient Deficiencies Affect Mental Health (34:50) How Oxygen Powers Health and Longevity (48:04) Hormone Balance and Energy Optimization (51:36) The Impact of Sugar on Metabolic Health (57:46) Why Physical Discomfort Slows Aging (1:01:18) Real Biohacking Health Transformation Stories Gary Brecka is a human biologist, biohacker, and co-founder of 10X Health System, a wellness company specializing in genetic testing and personalized supplementation. With over 20 years of experience in biohacking and functional medicine, he helps people optimize their health and performance. Gary also hosts The Ultimate Human podcast, where he interviews leading researchers and physicians on bio-optimization, longevity, and overall well-being. Sponsored By: Indeed - Get a $75 sponsored job credit to boost your job's visibility at Indeed.com/profiting Shopify - Start your $1/month trial at Shopify.com/profiting. Spectrum Business - Keep your business connected seamlessly with fast, reliable Internet, Phone, TV, and Mobile services. Visit https://spectrum.com/Business to learn more. Northwest Registered Agent - Build your brand and get your complete business identity in just 10 clicks and 10 minutes at northwestregisteredagent.com/paidyap Framer - Publish beautiful and production-ready websites. Go to Framer.com/profiting and get 30% off their Framer Pro annual plan. Quo - Run your business communications the smart way. Try Quo for free, plus get 20% off your first 6 months when you go to quo.com/profiting Experian - Manage and cancel your unwanted subscriptions and reduce your bills. Get started now with the Experian App and let your Big Financial Friend do the work for you. See experian.com for details. Bitdefender - Start protecting your business today with Bitdefender Ultimate Small Business Security. Get 30% off your plan at bitdefender.com/profiting  Intuit - Start paying bills the smart way, not the hard way. Learn more at QuickBooks.com/billpay   Resources Mentioned: Gary's Instagram:instagram.com/garybrecka Gary's Podcast, The Ultimate Human: bit.ly/TUH-apple  10X Health Gene Test: 10xhealthsystem.com Active Deals - youngandprofiting.com/deals  Key YAP Links Reviews - ratethispodcast.com/yap YouTube - youtube.com/c/YoungandProfiting Newsletter - youngandprofiting.co/newsletter  LinkedIn - linkedin.com/in/htaha/ Instagram - instagram.com/yapwithhala/ Social + Podcast Services: yapmedia.com Transcripts - youngandprofiting.com/episodes-new  Entrepreneurship, Entrepreneurship Podcast, Business, Business Podcast, Self Improvement, Self-Improvement, Personal Development, Starting a Business, Strategy, Investing, Sales, Selling, Psychology, Productivity, Entrepreneurs, AI, Artificial Intelligence, Technology, Marketing, Negotiation, Money, Finance, Side Hustle, Mental Health, Career, Leadership, Mindset, Health, Growth Mindset, Motivation, Manifestation, Life Balance, Self-Healing, Positivity, Happiness, Sleep, Diet

If you're a woman - or you love one! - this episode will change how you understand women's bodies. Because here's the sad truth: Women's health has been built on research that largely ignored women. We've been handed one-size-fits-all advice for bodies that are anything but. And millions of moms are walking around exhausted, depleted, hormonally off, and wondering, “Why the hell do I feel like this?” So today, we're going deep into what's actually happening inside women's bodies, and what real support should look like.Deena sits down with Victoria Thain Gioia, co-founder and CEO of Perelel, a doctor-backed women's health brand created after her daughter was born with a nutrition-related birth condition - a moment that exposed just how massive the gaps are in prenatal and maternal care.Together, they unpack the reality women live every day:• Hormones that shift constantly• Nutrient needs that change across life stages• The invisible physical load of motherhood• The pressure to function while depleted• Why “just take a vitamin” was never enoughThis episode is design to be practical, with simple tweaks you can start making today to optimize your health. You'll learn:✔ Why women's bodies need different support than men's✔ The biggest daily nutrition gaps affecting moms✔ How protein, fiber, and muscle health impact hormones and energy✔ Why simple routines matter more than perfection✔ What “stage-specific” support actually means✔ The small daily shifts that help women feel better in their bodiesThis conversation is equal parts science, motherhood reality, and permission to make yourself high up on your to-do list. If you've ever felt exhausted, off, depleted, or like your body changed after kids, this episode will make you feel seen, informed, and empowered to start supporting yourself again. Because moms give everything. It's about damn time someone supported YOU.Visit www.perelelhealth.com and use code BIGLITTLEFEELINGS for 20% off your first purchase.This episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct, or indirect financial interest in products, or services referred to in this episode.Bobbie - Head to hibobbie.com to find the formula trusted by parents and loved by their babies–700k and counting. Experian - Get started with the Experian App now! See experian.com for details.Nutrafol - Head to nutrafol.com and enter the promo code FEELINGS for $10 off your first month's subscription and free shipping. Square - Get up to $200 off Square hardware when you sign up at square.com/go/BLF. #squarepod Produced by Dear MediaTypeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Testosterone Replacement Therapy can transform men's mental health and sexual performance. We cover low testosterone symptoms, treatment benefits, and what you need to know before starting TRT. Learn more at https://trtaustralia.com/category/blog/ TRT Australia City: Hurstville Address: 7–11 The Avenue Website: https://trtaustralia.com/x

You don't have to overhaul your life with your New Year's Resolutions. Small habits, when done consistently, can completely change your health trajectory– changing your LIFE.  In today's episode, I'm flipping the script on midlife health—because you don't need another restrictive plan or pressure-filled protocol to feel better.  Instead, I'm sharing my top five simple yet powerful habits that can truly shift your energy, metabolism, and mindset in midlife.  These are realistic, supportive practices designed to meet you where you are, not demand more discipline or perfection.  You'll also hear how you can build real momentum alongside thousands of women in my FREE 7-day Metabolism & Hormone Jumpstart Challenge. In just one week, you can reignite your energy, reset your metabolism, and start feeling like yourself again—without willpower battles or crash diets.  Tune in here for a science-backed, supportive reset that actually works! IN THIS EPISODE Overcoming the post-holiday season fatigue and burnout  The reset you need to start the new year right Looking at your own habits that make your life run smoother My top 5 go-to habits to boost energy and metabolism  How consistency with even ONE of these habits is life-changing All about my FREE 7-day Hormone & Metabolism Jumpstart  QUOTES “The holiday season– it's a lot. It's a lot on our nervous system. It's a lot on our metabolism, it's a lot on our hormones. And [all the] while midlife, perimenopause, and menopause are playing behind the scenes.” “Here's the thing, you don't need to do all the things, but choose one habit. And committing to it can change your entire health trajectory, and that changes your life.” “You need a jumpstart that honors your body and nervous system right now. This isn't about perfection; it's about momentum. This isn't about restriction, it's about support. It's about wins. So let's do this together.” RESOURCES MENTIONED Sign up for my 7-day Hormone & Metabolism Jumpstart https://drmariza.com/jumpstart Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ RELATED EPISODES  707: Before You Plan 2026, Ask Yourself This: 12 End-of-Year Questions to Realign Your Energy, Goals, and Hormones 704: Hormone Intelligence for Women in Midlife: How to Thrive Through Perimenopause with Dr. Aviva Romm 690: The Perimenopause Revolution: Why midlife isn't the end — it's the beginning of your most energized, powerful, and vibrant self 686: Your Second Puberty Explained: What's Really Happening to Your Body in Perimenopause 

A Guide for Women to Achieve Health Span

What do distributors of wellness products and, say, industrial fasteners have in common? More than you think. While the inventory and customer bases differ, the lessons learned in their respective trenches are universal.  Matthew James, president and CEO of Purity Life Health Products LP in Canada, agrees. He just closed on a major acquisition 13 years in the making and has advice for anyone navigating a complicated integration process. Jason caught up with Matthew to find out how he and his team are managing employee expectations, continuing to foster innovation, and planning for the future. CONNECT WITH JASON LinkedIn CONNECT WITH MATTHEW LinkedIn Purity Life *** For full show notes and services visit: https://www.distributionteam.com Distribution Talk is produced by The Distribution Team, a consulting services firm dedicated to helping wholesale distribution clients remove barriers to profitability, generate wealth, and achieve personal goals.    This episode was edited by The Creative Impostor Studios  Special thanks to our sponsors for this episode: Connected Peers, providing virtual communities for wholesale distributors; and INxSQL Distribution Software, an integrated distribution ERP software designed for the wholesale and distribution industry.

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In this episode of the All Bodies Nutrition podcast, host Eleni welcomes Jen Rudnick, a social media influencer who shares her journey of authenticity in the digital space. They discuss the importance of being real and raw on social media, navigating family dynamics as an influencer, and the significance of health and longevity as they age. Jen shares her experiences with hormone replacement therapy, the role of exercise in maintaining health, and her approach to nutrition without dieting. The conversation also touches on mental health, anxiety, and the importance of finding balance in life as they embrace the changes that come with aging.More About Jen:Click here to follow Jen on InstagramClick here to follow Jen on TikTok- - - - - - - -More About Eleni:Join the Body Kind Nutrition community as a free or paid member:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here to sign up and join our Body Kind Nutrition community on patreon⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Eleni Agresta Levine MS RDN is a weight-inclusive registered dietitian who helps women heal their relationship with food and their bodies. She works with clients virtually and is a Health at Every Size (HAES®) aligned healthcare provider.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Eleni's Instagram: @all.bodies.nutrition⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Interested in working with Eleni? Click here to apply⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email Eleni at: All.Bodies.Nutrition@gmail.com

Emma Heatherington, Author

In this week's Spiritual Perspective, we explore what I call The Constantinople Effect—the tendency to give up too soon when the path forward feels “too hard,” and to rationalize it with phrases like, maybe it's just not meant to be.Drawing from the dramatic fall of Constantinople, we'll look at what happens when conventional efforts aren't enough—and why sometimes the only way through is to consider the “impossible.” Just as the Ottoman army hauled seventy massive warships over land to outflank the city's defenses, we, too, may need to challenge our assumptions about what's possible in order to reclaim neglected areas of our lives.The paradigm shift here is clear: difficulty is not a sign to quit—it's often proof you're on the right path. Spiritual growth isn't about waiting for the universe to fix things; it's about expanding your sense of possibility and aligning with the courageous actions that transformation demands.Recommended episodes to check out: The Spiritual Perspective on Going with the FlowThe Easy Life LifeJoin me for the upcoming Fall Meditation Workshop in Mexico City. More details here: mexico.beginmeditating.com.Send us a text message. We'd love to hear from you!

Irish Life Health, which has around 500,000 customers, has announced a 3% average rise in the cost of its plans for adult health insurance policies from October. Aengus Cox, Consumer Affairs Correspondent, reports.

Connect with Leanne on Social Media:    Instagram: www.instagram.com/awakeningwomenofficial/  Facebook: www.facebook.com/awakeningwomenofficial/ Youtube: https://www.youtube.com/theevolvedfeminine Website: leanneoaten.com    Step into Your Next Level:   Private Exclusive Coaching Application: https://leanneoaten.com/quantumcoaching Leanne Oaten is a former Registered Professional Counsellor with a background in Counselling Psychology and has over 13 years of experience counselling and coaching women. This podcast is for high-achieving women who refuse to settle in a life that looks successful on the outside but feels empty on the inside. If you're juggling business, career, family, and a relationship that doesn't light you up while secretly craving more freedom, more money, and more joy - this is the podcast for you. I help women reclaim their power, build unshakable self-trust, and create the kind of life they no longer want to escape from. We're not here to hustle harder or burn it all down. We're no longer focused on changing men, we are building for ourselves so that we never settle again, and can call in aligned partners who want to build together as a power-couple.  We're here to make power moves with ease, and feminine energy that attracts everything you want without losing yourself in the process. So if you're ready to stop waiting for him to change, stop negotiating your worth, and start embodying the woman you want to be, welcome home. Let's dive in.

Today Nikita talks with Tamsey Smith for another Man up show

In this episode, Sean Cox sits down with Dean Lambert, the Director of the Life Insurers Council to explore the unique challenges faced by small to mid-size life insurance companies and discuss practical strategies for doing more with less—through innovation, collaboration, and resourceful leadership.

In this Coach Chat, Lisa gets real with a personal health update, shares the dietary changes she's making to support her journey, and takes you inside her latest grocery haul. Tune in for honest insights, practical tips, and a peek at what's fueling her wellness goals.

Ep 34 – The Power of Muscle: Strength Training for Real Life Health Part 2 In this powerful follow-up episode of Walk, Don't Run to the Doctor, Dr. Miles Hassell and Jennifer Smith of Starting Strength Beaverton dig deeper into the mindset behind fitness—and how strength training can be a surprising antidote to loneliness, mental fatigue, and life's hardest decisions. Key Takeaways: “Everything we do, we do twice—first in our mind, then in action.” Jen explores how mental preparation is just as vital as physical strength. Decision fatigue is real—but strength training helps you build discipline and identity through repetition and intention. Fitness as a cure for loneliness: How small-group strength training builds unexpected, life-giving community—especially for older adults. Shared purpose connects generations: Stories of gym members aged 18 to 81 lifting side-by-side, building both muscle and friendships. Why strength training is more than just physical—it's a vehicle for mental resilience, connection, and even faith. Whether you're seeking better health, a support system, or a stronger mindset, this episode offers a hopeful roadmap. Like, comment, and share to inspire someone today. #WalkDontRunPodcast #StrengthTraining #MentalHealth #Loneliness #HealthyAging #BarbellTraining #StartingStrength #CommunityFitness #FaithAndFitness More references can be found at www.GreatMed.org Would you like Dr. Hassell to answer your question on the air?  Contact us! Phone/text: 503-773-0770 e-mail: info@GreatMed.org Write us a letter.  We love to hear from you.  This podcast is sponsored by our generous listeners.  Send questions, comments, and support to: 4804 NW Bethany Blvd., Suite I-2, #273 Portland OR 97229

Rhomas Men's Team podcast here. As always, if you resonate with our content, please follow, like, share, comment, and support our channel: https://www.rhomas.com/ Welcome to another episode of Rhomas Men's Team! In this episode, we dive deep into goal setting, financial success, and self-improvement to help you become the best version of yourself. Key Takeaways: ✔ Start Early & Stay Consistent – Why wait for January? Get ahead on your goals now. 
✔ The 4 Pillars of Life – Health, Wealth, Relationships, and Enjoying the Process.
 ✔ The Truth About Debt – How credit cards trap you and how to break free.
 ✔ Money is a Tool, Not the Enemy – Why financial success brings freedom and security.
 ✔ Earn More, Not Just Save More – The secret to long-term financial growth. 
✔ Lessons from Jeff Bezos and Tom Brady – Strategic sacrifices for ultimate success. Moral of the story: Increase your value, take control of your finances, and start living with purpose. Join the movement and level up! Like, Comment, and Subscribe for more content on self-improvement and financial freedom. #SelfImprovement #FinancialFreedom #GoalSetting #MensSuccess #RhomasMensTeam #SuccessMindset #PersonalDevelopment #StayFocused #HardWorkPaysOff 

Some experts insist we should ditch the dumbbells and pick up a barbell. Are they right? Welcome to Walk, Don't Run to the Doctor with Miles Hassell, MD. In this episode, we dive deep into the transformative power of strength training—not just for fitness, but for long-term health and independence.  Whether it be dumbbells, barbells, a toddler, or heavy backpack, add any kind of weight-bearing exercise every day for muscle mass benefits. Our guest, Jennifer Smith, owner of Starting Strength Beaverton, shares her personal journey into barbell training and how it became her calling to help others age with strength, dignity, and vitality.  Key Takeaways: Muscle mass is medicine: Strength training supports bone health, balance, posture, and even chronic disease reversal. Prevent or reverse disease: Learn how building strength can combat type 2 diabetes, osteoporosis, and more. Real-life inspiration: Hear about Marjorie, a 96-year-old client who embraced lifting to improve her quality of life. Fitness is for everyone: Even busy parents and professionals can find ways to build strength safely and sustainably. Mindset and community matter: Loneliness, aging, and motivation are tackled through group training and supportive coaching. Whether you're new to lifting or looking for encouragement to keep going, this episode reminds you: it's never too late to get stronger. #StrengthTraining #PreventativeHealth #MuscleMass #HealthyAging #StartingStrength #FitnessOver40 #ReverseChronicDisease #WalkDontRunPodcast More references can be found at www.GreatMed.org Would you like Dr. Hassell to answer your question on the air?  Contact us! Phone/text: 503-773-0770 e-mail: info@GreatMed.org Write us a letter.  We love to hear from you.  This podcast is sponsored by our generous listeners.  Send questions, comments, and support to: 4804 NW Bethany Blvd., Suite I-2, #273 Portland OR 97229

About Paul H. Flowers Jr.The Story of Paul H. Flowers Jr. — A Leader Built by Life, Ready to Ignite Your AudienceBefore Paul H. Flowers Jr. ever built companies, led national sales teams, or launched transformational initiatives across the insurance and financial worlds — he built people.Raised with the values of leadership, resilience, and faith, Paul didn't just learn how to succeed in business; he learned how to succeed in life. Early in his career, he found himself managing teams, solving complex problems, and mentoring others who would go on to create legacies of their own. Paul became the leader people turned to when the stakes were high — not because he sought the spotlight, but because he earned their trust.Over the years, Paul's entrepreneurial spirit ignited. He founded Superior Insurance Advisors and the nonprofit Life Health and Legal Education Partners to bridge the dangerous gaps he saw between everyday families and critical knowledge about healthcare, financial literacy, and legal rights. His mission is rooted in a simple but powerful belief: education and empowerment can change lives — and generations.https://www.linkedin.com/in/paulhflowersjr/http://www.paul.health/----------------------------------About Dustin HoogFrom Burned-Out Agent to Wealth Builder — Why I'm on a Mission to Help REALTORS Create FreedomFor years, I played the game most REALTORS know all too well — chasing commission checks, grinding out every deal, and telling myself I was “building something.” But behind the scenes, I was trapped. Trapped in a business that only paid me when I was hustling nonstop. And worse, I didn't own anything that created real wealth or freedom.Then I flipped my first house. That one deal changed everything. I realized that I could build wealth through real estate investing — not just sales. From there, I went all in. I started flipping homes, buying rentals, and creating income streams that worked even when I didn't. And guess what? I didn't have to stop being a REALTOR to do it.http://www.dustinhoog.com/----------------------------------When It Worked Podcasthttps://getoffthedamnphone.com/podcast

Hi Parents, Is your teen constantly criticizing their body, obsessing over food, or showing sudden changes in eating habits? You're not alone - and neither are they. In this episode, I'm sitting down with Leslie to explore the deeper roots of disordered eating and body anxiety in teens. We dive into how these struggles often stem from anxiety, low self-esteem and the need for control. Leslie offers insight into what disordered eating actually looks like, the early warning signs to watch for, and why resistance or denial is a common first reaction when teens are approached. You'll learn how to start supportive conversations without adding pressure, how to help your teen build self-awareness, and why creating healthy habits before college is one of the most important things you can do. More About Leslie: Leslie is a triple-certified Life, Health, and Nutrition Coach who specializes in working with teens and parents to overcome disordered eating, body anxiety, and low self-esteem. She is the host of the Healthy Teen Life podcast and offers personalized coaching programs designed to help teens develop balanced relationships with food and themselves. Her unique program focuses on powerful mindset shifts, empowered eating strategies and self-compassion tools. The result? Confident young adults who overcome weight challenges, develop healthy relationships with food, and unlock their potential for happier, healthier lives. This episode is filled with practical advice and real-life examples that will help you better support your teen's mental and physical well-being - with empathy and confidence.

Rhomas Men's Team podcast here. As always, if you resonate with our content, please follow, like, share, comment, and support our channel: https://www.rhomas.com/ Welcome to another episode of Rhomas Men's Team! In this episode, we dive deep into goal setting, financial success, and self-improvement to help you become the best version of yourself. Key Takeaways: ✔ Start Early & Stay Consistent – Why wait for January? Get ahead on your goals now. ✔ The 4 Pillars of Life – Health, Wealth, Relationships, and Enjoying the Process. ✔ The Truth About Debt – How credit cards trap you and how to break free. ✔ Money is a Tool, Not the Enemy – Why financial success brings freedom and security. ✔ Earn More, Not Just Save More – The secret to long-term financial growth. ✔ Lessons from Jeff Bezos and Tom Brady – Strategic sacrifices for ultimate success. Moral of the story: Increase your value, take control of your finances, and start living with purpose. Join the movement and level up! Like, Comment, and Subscribe for more content on self-improvement and financial freedom. #SelfImprovement #FinancialFreedom #GoalSetting #MensSuccess #RhomasMensTeam #SuccessMindset #PersonalDevelopment #StayFocused #HardWorkPaysOff

Rhomas Men's Team podcast here. As always, if you resonate with our content, please follow, like, share, comment, and support our channel: https://www.rhomas.com/   Welcome to another episode of Rhomas Men's Team! In this episode, we dive deep into goal setting, financial success, and self-improvement to help you become the best version of yourself. Key Takeaways: ✔ Start Early & Stay Consistent – Why wait for January? Get ahead on your goals now. ✔ The 4 Pillars of Life – Health, Wealth, Relationships, and Enjoying the Process. ✔ The Truth About Debt – How credit cards trap you and how to break free. ✔ Money is a Tool, Not the Enemy – Why financial success brings freedom and security. ✔ Earn More, Not Just Save More – The secret to long-term financial growth. ✔ Lessons from Jeff Bezos and Tom Brady – Strategic sacrifices for ultimate success. Moral of the story: Increase your value, take control of your finances, and start living with purpose. Join the movement and level up! Like, Comment, and Subscribe for more content on self-improvement and financial freedom. #SelfImprovement #FinancialFreedom #GoalSetting #MensSuccess #RhomasMensTeam #SuccessMindset #PersonalDevelopment #StayFocused #HardWorkPaysOff  

Celebrating 100 episodes of the Nourished Babes Podcast by sharing 100 life and health lessons! SUBSCRIBE HERE: https://creators.spotify.com/pod/bella-madisen/subscribe Our websites:  thegutgoddess.com nourishwithbella.com

AM Best Industry Analyst Helen Andersen discusses two new Best's Special Reports on property/casualty and life/health 2024 rating trends.

Welcome to the Disrupt the System Podcast, where we challenge outdated norms and redefine what's possible for driven women seeking freedom, wealth, and health. In today's episode, I sit down with my friend, past client, and powerhouse coach Kristel David—an entrepreneur, speaker, and host of Her Playbook. Kristel is deeply passionate about helping wives and mothers rediscover their worth, reclaim their power, and create thriving lives. After navigating her own transformative journey through divorce, she has become a beacon of hope for women ready to break free from societal expectations and rewrite their own stories. What You'll Learn in This Episode: ✨ Kristel's personal evolution—from being an NFL wife and mother of five to a thriving entrepreneur and mentor ✨ The reality of rebuilding life after divorce, both personally and professionally ✨ The unexpected ways stress manifests in the body—and how Kristel learned to listen to her body's signals ✨ The impact of holistic health and functional medicine on her healing journey ✨ How perfectionism can sabotage health and success—and what to do instead ✨ The power of self-advocacy and asking for support without shame ✨ Why surrender and trust are the key themes for 2025 Kristel shares candidly about the toll stress took on her body—from joint pain and TMJ to digestive issues and chronic fatigue—and how her journey with functional health helped her reclaim her vitality. We also dive deep into how women often resist asking for help and the life-changing shift that happens when we fully receive support. This conversation is full of raw truth, powerful insights, and actionable takeaways for any woman navigating transitions, burnout, or the pressure to do it all alone. Resources & Mentions:

Emily and Terry come together for the highly anticipated segment, Terry's Top Ten Tips, where Terry shares his top insights on life, health, business, family, and more. Join this engaging father-daughter conversation filled with wisdom, practical advice, and heartfelt moments!   Read the book unstressable: https://rstyle.me/+_FJypCtUpLCkRO9tbtH6sQ   Follow me on Instagram:  https://www.instagram.com/emilyoandbows/?hl=en Shop our collections:  https://emilyoandbows.com/    

In this powerful episode, we delve into the concept of EXTREME Gratitude — a mindset that can shift the way we experience life's challenges and blessings. Join us as we reflect on the fragility of life and howtragedy can serve as a stark reminder to cherish every precious moment with our children. From personal stories of heartache and near-loss to practical advice for cultivating a deeper sense of appreciation, this episode encourages parents to embrace gratitude over frustration. Learn how you can correct your child's behavior with love, not irritation, and how focusing on what truly matters can transform the way you parent. This sobering, yet hopeful message will inspire you to embrace life with greater intention and show your children how much they are truly cherished.More videos on challenging situations that caused us to focus on what truly matters:RESOURCES:Let us help you in your extraordinary family life journey:JOIN GREG'S ⁠90-DAY HEALTH & FITNESS CHALLENGE⁠! Get Rachel's⁠⁠⁠Family Systems & Charts⁠⁠⁠Join the⁠ ⁠⁠28-Day Challenge⁠⁠⁠ for MomsRachel's ⁠⁠⁠Must-Read Booklist for Well-Read Moms⁠⁠⁠⁠Greg's⁠⁠⁠Recommended Reading List for Parents & Youth⁠⁠⁠Join the ⁠Formidable Family Man Masterclass and Tribe⁠Join Greg's ⁠7-Day Challenge ⁠Follow us on Instagram:⁠⁠@worldschoolfamily⁠⁠ or⁠⁠@greg.denning⁠⁠Gather with us at the⁠⁠World School Family (Beach & Farm) Resort⁠⁠ in PortugalRead our reviews here: ⁠https://podcast.extraordinaryfamilylife.com/review⁠--- Send in a voice message: ⁠https://podcast.extraordinaryfamilylife.com/voicemail/

Jess and Anissa are diving deep into the wild world of parenting, health fads, and the ridiculous ways celebrity culture messes with our minds. From decoding text messages (because, let's be honest, they always get misread) to surviving single parenting with a sense of humor, they're keeping it real. They're also calling out the latest health trends—because, spoiler alert, not everything on Instagram is actually good for you. Add in a little community support, questionable food choices, and the joys (and disasters) of motherhood, and you've got a conversation you won't want to miss. Let's laugh through the chaos together!

Wacth here: https://youtu.be/fVEnPAHFAw8Join us as we sit down with Dr. Sabrina Baker and discuss the deep and profound connection between our spirit, soul, and body.https://www.thesoultrap.com/Podcast: https://thesoultrap.buzzsprout.com/Support the show

Trey Davis from Sun Life Health talks about power of Sunoh.ai in medical documentation. Learn how this AI technology captures diverse dialects with precision, enhancing the accuracy of medical records. Discover how Sunoh.ai is enhancing healthcare by saving providers valuable time and significantly improving patient communication.

In this episode, we sit down with the dynamic and relatable Jenny Hutt – best known for the podcast “Just Jenny,” and an entrepreneur with her Shark Tank product, “Bunny Eyez” plus many other titles she's held over the years! We have a candid conversation about life, health, parenting, weight loss, and navigating the complexities of social media. Jenny opens up about her personal journey, sharing insights into how she balances being a mom while pursuing her passions and staying authentic in the public eye. We also get a behind-the-scenes look at what it's like to interview A-list celebrities and how she keeps it real with both her audience and her guests. From tackling self-image to sharing her favorite tips for staying motivated, Jenny's honesty and humor make this episode a must-listen. Tune in for an engaging chat filled with inspiration, laughs, and practical wisdom. For more information about Jenny or to listen to her podcast go to: Just Jenny Follow her on Instagram Or to find out about Bunny Eyez go to: bunnyeyez.com Follow us on Instagram: @every.body.talks @jenngiamo @schully Don't forget to subscribe to the podcast for free wherever you're listening. Apple Podcasts Spotify Be sure to leave a 5 star rating! It really helps grow the show. If you like the show, telling a friend about it would be amazing!

Life can be hectic, and finding time for healthy eating and exercise is often challenging. Dr. Kim Colangelo joined us to share her practical suggestions for meal planning, staying active, cooking for a family, and what actually works for reaching a healthier weight. These are real-life tips that EVERYONE can find helpful.The medical information in this podcast is provided as an information resource only. It is not in any way intended to be nor should you rely on it as a substitute for professional medical evaluation, diagnosis, advice and treatment.This episode was sponsored by Novo Nordisk. It was created independently by My Weight - What to Know with no influence from Novo Nordisk.

This time, I'm speaking freely without a set topic, just sharing my thoughts! Reflecting on a busy yet fulfilling 2024, I talk about life in Osaka, new hobbies, time with friends, and my thoughts on health. I also honestly share realizations about my “easily bored” personality and changes in my physical strength. I encourage listeners to try expressing their own feelings—whether by talking, writing, or finding another way to let it out. It's a great way to care for yourself! Check out our transcripts, video podcasts, and Japanese learning resources at⁠⁠: https://sayurisaying.com/unscripted-reflections/ Your support helps keep this podcast alive and means a lot to me. Thank you for considering!

Sharons Journey over the years has been AMAZING and one to talk of... through a host of health issues, perimenopause and navigating this thing called LIFE... you dont exist in isolation all to do with food and training theres so much more to this ! STOP JUDGING YOURSELF for where you are right now, past failures, whatever it is. sharonrichardsspiritualmedium@gmail.com sharonrichardsspiritualmedium sharonrichardsspiritualmedium.com

In this deeply personal episode, my wife Alyson Charles Storey joins me as we open up about some recent challenges and discoveries we've been navigating. From taking full-body health scans at Prenuvo to Alyson's discovery of lumps in her breast, we share how we faced our fears and took proactive steps for our health. We also reflect on the emotional journey of saying goodbye to our beloved cat, Jellybean, and how we honored his life. Join us as we discuss navigating uncertainty, grief, and the inevitable truths of life. Check out prenuvo.com/lukestorey for $300 off a whole-body scan.DISCLAIMER: This podcast is for educational purposes only and not intended for diagnosing or treating illnesses. The hosts disclaim responsibility for any adverse effects from using the information presented. Consult your healthcare provider before using referenced products. This podcast may include paid endorsements.THIS SHOW IS BROUGHT TO YOU BY:UPGRADED FORMULAS | Go to upgradedformulas.com and use code LUKE15 TO SAVE 15%.QUANTUM UPGRADE | Get a 15 day free trial with code LUKE15 at quantumupgrade.io.BEAM MINERALS | Use code LUKE for 20% off your order at beamminerals.com.NUCALM | Go to nucalm.com and use code LUKE for 15% off!MORE ABOUT THIS EPISODE:(00:00:00) Introduction(00:00:08) Health Check with Prenuvo Full-Body Scan(00:12:34) Alyson's Recent Health Discovery(00:30:17) Lessons from Navigating Fear & Uncertainty(00:46:42) How to Honor a Pet's Final Days(00:57:39) Jellybean's Crossing Over Ceremony & Tips for Healthy Grieving(01:14:40) Jellybean's Final Gift & Pondering Mortality Resources:• Visit prenuvo.com/lukestorey for $300 off your whole-body scan• Ceremony Circle Podcast: alysoncharles.com/podcast• Animal Power: alysoncharles.com/animalpower• Instagram: @iamalysoncharles • Shop all our merch designs at lukestoreymerch.com• Check out Gilded By Luke Storey: gildedbylukestorey.com• Join me on Telegram: https://t.me/lukestoreyThe Life Stylist is produced by Crate Media.

Dr. Gordon Smith and Dr. Whitley Aamodt discuss end-of-life care for patients with neurodegenerative diseases, focusing on healthcare utilization, hospice enrollment, and the importance of early conversations about care preferences. Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000209925    

Dr. Gordon Smith talks with Dr. Whitley Aamodt about the comparison of resource utilization between US Medicare decedents with neurodegenerative diseases and those with cancer. Read the related article in Neurology. Disclosures can be found at Neurology.org.

This week, Rye & Jess are sharing some big life and health updates, including finding and removing mold, moving, pup parenting, managing chronic headaches/migraines & launching a membership!  RESOURCES MENTIONED: MYCOTOXIN TEST  By vibrant wellness (ordered through Functional Practitioner, Tiffany Kaloustian):  https://embracingthedance.wellproz.com/patient/product/60959 https://embracingthedance.wellproz.com/patient/product/27572 MOLD IN YOUR HOME 101  Tune into our conversation w/Michael Rubino of HomeCleanse: “Why you Should Care about the Health of your Home (Addressing Mold & Compromised Air Quality): https://podcasts.apple.com/gb/podcast/why-you-should-care-about-the-health-of-your/id1482677618?i=1000647421734 TESTING FOR MOLD IN YOUR HOME: LA area company we used: https://www.jlmenvironmental.com/ Another highly recommended company: https://yesweinspect.com/ CONNECT WITH RYE & JESS Follow us ⁠⁠⁠⁠⁠⁠@solo2.0podcast⁠⁠⁠⁠⁠⁠ Email us at ⁠solo2.0podcast@gmail.com⁠ Follow ⁠⁠⁠⁠⁠⁠@bodyblissbyjess⁠⁠⁠⁠⁠⁠ Follow ⁠⁠⁠⁠⁠⁠@ryeburch

NOW ON YOUTUBEWelcome to "Coffee Talk with Cari and Heather," a special podcast series where best friends Cari and Heather Centurioni sit down over coffee to chat about all things faith, life, health, and personal growth. Each episode covers real-life topics like overcoming challenges, finding balance, improving your health, and deepening your relationship with God. With laughter, honesty, and heartfelt insights, these conversations are sure to encourage and inspire you on your journey toward spiritual and physical well-being. Grab your coffee and join us for these fun, uplifting discussions that will leave you feeling empowered in every area of life.URHERE Information- www.verycaripodcast.com/urhereConnect with Cari:Instagram: instagram.com/carithompsonrnFacebook: www.facebook.com/cari.ayres.3Website:     VeryCariPodcast.comConnect with Heather: NEW PROGRAM:  Plate to PurposeWebsite:  www.heathercenturioni.comInstagram: www.instagram.com/heather_centurioni

This week on the Journey to Launch Podcast, I have a powerful conversation with Esther Hyun, a stage four colorectal cancer survivor and lawyer, who opens up about her journey to financial independence. Esther highlights the need to balance financial goals with personal well-being, while stressing the importance of preventative health care. She also discusses the financial challenges of navigating cancer treatment, such as unexpected out-of-network medical bills, and underscores the value of life insurance, estate planning, and much more. In this episode, we discuss:  Esther's financial foundations which allowed her to be debt-free except for student loans and how she contributes to HSAs and 401(k)s to build wealth Esther's experience of being diagnosed with colorectal cancer at 36, the financial impact it had on her, and the importance of having a plan in place for unexpected events. Life insurance, estate planning, and balancing financial independence with enjoying life in the present. Other Links Mentioned in episode: All About The Health Savings Account (HSA) -The Ultimate Retirement and Investment Account w/ Jackie Koski Get your copy of my book: Your Journey To Financial Freedom Leave Your Journey To Financial Freedom a review! Get The Budget Bootcamp Check out my personal website here. Join The Weekly Newsletter List Leave me a voicemail– Leave me a question on the Journey To Launch voicemail and have it answered on the podcast! YNAB –  Start managing your money and budgeting so that you can reach your financial dreams. Sign up for a free 34 days trial of YNAB, my go-to budgeting app by using my referral link. What stage of the financial journey are you on? Are you working on financial stability or work flexibility? Find out with this free assessment and get a curated list of the 10 next best episodes for you to listen to depending on your stage. Check it out here! Connect with Esther: Instagram:@ParentingwithCancer TikTok: @ParentingwithCancer Connect with me: Instagram: @Journeytolaunch Twitter: @JourneyToLaunch Facebook: @Journey To Launch Join the Private Facebook Group Join the Waitlist for My FI Course Get The Free Jumpstart Guide

These 10 Rules for Health and Fat loss are the ESSENTIALS for losing weight, keeping it off, and building sustainable habits for life. In this episode, Jared goes into the deeper side of weight loss and behavior change. So of the rules go into: - Your "WHY" doesn't help as much as you think (what helps more) - Navigating "I don't feel like it" - What does it mean when you feel resistance? - You don't need to do as much as you think How you can text Jared with any of your Questions! Text 765-308-5751 Don't forget to subscribe! Enjoy! TIMESTAMPS: (00:00) - Intro (01:02) - Start of the episode & reminders (04:00) - Rule #1 - You are NOT helpless (12:16) - Rule #2 - You don't need to do as much as you think... (15:20) - Rule #3 - Resistance is required (22:33) - Rule #4 - You are supposed to get bored (26:14) - Rule #5 - You can have any foods you want... just not as much as you want (29:22) - Rule #6 - Your "WHY" needs avoidance of pain (Hell List) (34:20) - Rule #7 - Appreciate motivation, don't rely on it (40:48) - Rule #8 - Shift your identity to who you want to become (43:54) - Rule #9 - Honor ALL of your wins (47:00) - Rule #10 - Don't compare to others (they are lying) (53:10) - Quick recap (53:57) - Free resources + working with Jared GET ON THE DIETING FROM THE INSIDE OUT COLLECTIVE WAITLIST: https://bit.ly/DFIOWaitlist APPLY FOR COACHING HERE: ⁠⁠https://link.arfunnel.io/widget/bookings/dietingfromtheinsideout⁠⁠⁠⁠⁠⁠ FREEBIES & SPECIAL OFFERS:‣ Join my free Facebook group & get all my trainings: https://www.facebook.com/groups/fatlosssimplified ‣ Get my [Free] Fat Loss Check-list Course: https://bit.ly/5daychecklist  ‣ Grab [Free] my 90-day blueprint on how to lose weight & never gain it back (without giving up the rest of your life): https://bit.ly/project90optin ‣ Get my 180 Academy 80% off: https://bit.ly/180AcademyScholarship ‣ Apply for 1:1 Coaching: https://inquire.hamiltontrained.com ‣ The best supplements for weight loss video: ⁠⁠https://www.youtube.com/watch?v=OfjByg4Zr_Y⁠⁠ ‣ 1st Phorm Supplement Training (from our Facebook community): ⁠⁠https://bit.ly/3hkBuLF⁠⁠ ‣ Get FREE shipping on 1st Phorm Supplements: ⁠⁠https://1stphorm.com/?a_aid=realjaredhamilton⁠⁠ ‣ Use promo code HAMILTONTRAINED for 20% off at: ⁠⁠https://www.flexpromeals.com⁠⁠ FIND ME ON: ‣ Instagram: ⁠⁠https://www.instagram.com/realjaredhamilton⁠⁠ ‣ YouTube: ⁠⁠https://www.youtube.com/@jaredhamilton⁠⁠ ‣ TikTok: ⁠⁠https://www.tiktok.com/@realjaredhamilton⁠⁠ ‣ Email: ⁠⁠jared@hamiltontrained.com⁠⁠ ---- © 2024 Jared Hamilton #podcast #dietingfromtheinsideout --- Support this podcast: https://podcasters.spotify.com/pod/show/dietingfromtheinsideout/support

We are George P. Kansas and Tracey Trottenberg Kansas and have been pouring our hearts and souls into the work of conscious communication, feminine and masculine leadership, and spiritual awakening for over 50 years combined. By now you've noticed something bold and unique about what we've got going on here.Why? Because, we like to do things differently. There is a ying and yang to all of us, a push and a pull, a masculine and feminine.There is wisdom in the interplay of these energies, and much to learn from both perspectives, ways of being, and the integration of the two.George is a recognized intuitive guide to performers, athletes, C-suite executives and entrepreneurs for nearly three decades, having shared the marquis with inspirational greats Zig Ziglar, Brian Tracy, and Denis Waitley.Tracey is a feminine-power alchemist who's coached or trained tens of thousands in the U.S., Canada, and Caribbean, and has shared the stage with luminaries such as Marianne Williamson, Les Brown, and Lisa Nichols.Contact George and Tracey!www.ConversationsGuide.com ThankYouBody.lovewww.GeorgeAndTracey.com Radical Empowerment LIVE is open for enrollment!  Get your tickets before the early bird discount disappears!  https://carrievee.com/radical-empowerment-liveJoin the Confidence and Clarity Membership!  https://carrievee.com/confidence-clarity-1Maxwell Method of Speaking Speakers club https://carrievee.com/maxwell-speakers-clubSchedule your Discovery Call with CarrieVee!https://schedulewithcarrievee.as.me/?appointmentType=12343596Book CarrieVee for a Speaking Engagement:  https://www.coachcarriev.com/contact-meStep Into Your Big Life Freebie: https://www.coachcarriev.com/stepintoyourbiglifefreebieRadical Empowerment Method Book on Amazon: https://amzn.to/3Bdp2BCGet to an EVENT!  www.carrievee.com/eventsContact CarrieVee!IG: @iamcarrieveeLI and FB: Carrie Verrocchioemail: carriev@coachcarriev.com 

#608: Today, we're sitting down with superfood expert, author, and podcast host, Darin Olien. Darin spent nearly 20 years exploring the planet, discovering new and underutilized exotic foods and medicinal plants. With his years of experience learning about the world's healthiest and most sustainable practices, he wrote both "SuperLife: The five fixes that keep you healthy, fit, and eternally awesome" & "Fatal Conveniences." Today, Darin joins us to discuss all things clean products, how to make small and easy changes that will benefit your life in the long run, and all things plant-based diet, including how to address the root causes of common health issues. To connect with Darin Olien click HERE To connect with Lauryn Evarts click HERE To connect with Michael Bosstick click HERE Read More on The Skinny Confidential HERE To subscribe to our YouTube Page click HERE For Detailed Show Notes visit TSCPODCAST.COM To Call the Him & Her Hotline call: 1-833-SKINNYS (754-6697) This episode is brought to you by The Skinny Confidential   This episode is brought to you by Barefaced Skincare Exclusively for Skinny Confidential listeners, bareface is offering 15% your first purchase off by using code SKINNY at barefaced.com. This episode is brought to you by Westin Hotels At Westin hotels, there's amenities and offerings aimed to help you move well, eat well, and sleep well, so you can keep your well-being close, while away. Find wellness on your next stay at Westin. This episode is brought to you by Sakara Sakara delivers science-backed, plant-rich nutrition programs and wellness essentials right to your door. Their ready-to-eat meals are nutritionally designed to deliver results—from weight management and eased bloat to boosted energy and clearer skin. Go to Sakara.com/skinny or enter code SKINNY at checkout to receive 20% off your first order. This episode is brought to you by LMNT LMNT is a tasty electrolyte drink that has everything you need and nothing you don't. It contains a science-backed electrolyte ratio: 1000mg sodium, 200mg potassium, and 60mg magnesium. Get a free sample pack with any purchase at drinkLMNT.com/SKINNY This episode is brought to you by AG1 AG1 is way more than greens. It's all of your key multi-vitamins, minerals, pre-and probiotics, and more, working together as one. Go to drinkAG1.com/SKINNY to get a free 1 year supply of vitamin D and 5 free travel packs with your first purchase. This episode is brought to you by eBay Ensure your next purchase is the real deal with eBay Authenticity Guarantee. Everyone deserves real. Visit ebay.com for terms. This episode is brought to you by DraftKings DraftKings Sportsbook is an official sports betting partner of the NFL. Download the DraftKings Sportsbook app now and receive $200 in bonus bets immediately by betting $5 and using code SKINNY at checkout. Produced by Dear Media