Podcasts about Biological psychiatry

L'expression "voir la vie en gris", souvent utilisée pour décrire un état dépressif, n'est pas qu'une simple métaphore. Elle correspond à un phénomène bien réel, documenté par les neurosciences : les personnes souffrant de dépression perçoivent les couleurs de façon altérée, notamment avec une réduction de la capacité à distinguer les contrastes visuels, ce qui donne littéralement une vision plus terne, plus grisée du monde.Une perception visuelle modifiée par la dépressionCe phénomène a été mis en évidence par plusieurs équipes de recherche, notamment dans une étude menée en 2010 par l'université de Fribourg en Allemagne, publiée dans la revue Biological Psychiatry. Les chercheurs ont montré que les patients dépressifs perçoivent moins bien les contrastes visuels, en particulier les contrastes liés à la luminance (la quantité de lumière reflétée par un objet). Cela rend les couleurs moins vives, les formes moins nettes, et la scène visuelle globalement plus plate.Les participants ont été soumis à des tests visuels, notamment à des images de rayures contrastées. Résultat : les personnes atteintes de dépression voyaient ces contrastes de manière significativement atténuée par rapport au groupe témoin non dépressif. Cette diminution de la sensibilité au contraste explique en partie pourquoi le monde semble "gris", sans relief ni éclat aux yeux des personnes concernées.Une origine neurologique : le rôle de la dopamineSur le plan biologique, cette altération serait liée à une baisse de la dopamine, un neurotransmetteur impliqué non seulement dans le plaisir et la motivation, mais aussi dans la régulation du traitement visuel dans la rétine. En effet, la dopamine joue un rôle crucial dans la transmission des signaux lumineux depuis la rétine vers le cerveau. Quand elle est déficiente — ce qui est fréquent chez les personnes dépressives — la réponse visuelle est affaiblie, en particulier dans la détection des contrastes.Ce lien entre humeur et perception visuelle suggère que la dépression n'affecte pas uniquement la pensée ou les émotions, mais modifie aussi la façon même dont le cerveau perçoit le monde physique.Une piste pour le diagnostic ?Ce phénomène pourrait même devenir un outil de diagnostic. Certaines recherches expérimentent l'usage de tests de perception des contrastes visuels comme indicateurs de l'état dépressif, ou pour mesurer l'efficacité des traitements. Si la sensibilité au contraste s'améliore, cela pourrait signifier que la dépression recule.En résumé, "voir la vie en gris" n'est pas une simple image poétique : c'est une réalité neurophysiologique. La dépression affecte la chimie du cerveau, et cela modifie notre vision au sens le plus littéral du terme. Le monde devient réellement plus terne, moins coloré… comme si l'émotion même s'était retirée de la perception. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

What happens in your brain when Cupid's arrow strikes? As a teenager, Alison developed an intense crush on George Harrison from the Beatles. But, she wants to know, why do we develop these feelings for pop stars we've never actually met? And what potent swirl of neurochemistry drives those fierce emotions?With neuroscientist Dr. Dean Burnett and evolutionary anthropologist Dr. Anna Machin as their guides, Hannah and Dara investigate everything from the brain's chemical fireworks during a crush to the evolutionary perks of love and bonding. Along the way, they dissect teenage infatuations, lifelong love affairs with football teams, and why love can feel as addictive as heroin.There's even a guest appearance from two cute rodents: the monogamous prairie voles and their more, shall we say, commitment-phobic cousins, the montane voles, who gave us early clues about the role of the ‘cuddle' hormone oxytocin. Whether you're a hopeless romantic or a hard-nosed skeptic, prepare to fall head over heels for the science of love.Contributors:Dr Anna Machin - evolutionary anthropologist and author of Why We Love Dr Dean Burnett - honorary research fellow at Cardiff Psychology School, author of The Idiot Brain and The Happy Brain. Carmine Pariante - Professor of Biological Psychiatry at King's College LondonProducer: Ilan Goodman Executive Producer: Alexandra Feachem A BBC Studios Audio Production

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This is our inaugural book club episode centered around the novel Mind Fixers by Anne Harrington.Mind Fixers is by the Harvard historian Anne Harrington, and came out from Norton in 2022. It reframes the “biological turn” in later twentieth century psychiatry with a history of the discipline from the later nineteenth century forward. Harrington argues that the biological turn had relatively little to do with new scientific advances, and came instead from a need to separate psychiatry from the increasingly unpopular public image of the discipline's previous, “Freudian” age. To make this argument, she starts with the anatomic research of turn-of-the-century figures like Kraepelin, and how this generally failed to explain important mental illnesses. She traces the emergence of “Freudian” or psychological approaches to mental illness to the high point of their dominance in the mid twentieth century, and then their decline, as their inadequacy with respect to things like bipolar disorder and schizophrenia became increasingly clear, and their emphasis on childhood experience stigmatized families. Biological psychiatry is then a way to restore the fields's respectability as as branch of medicine, but according to Harrington, there is not much transformative innovation to go along with this rebrand; and she emphasizes that the psychopharmacology revolution which gave us the first antipsychotics, MAOIS, tricyclics, and the receptor model of mental illness, actually happened during the heyday of psychoanalysis.The members of our team involved in this discussion are:Sara Abrahamson - MS2 at the University of TorontoDr. Kate Braithwaite - Medical Doctor from South AfricaDr. Wendy MacMillan-Wang - PGY4 psychiatry resident at the University of ManitobaDr. Alastair Morrison - PGY1 psychiatry resident at McMaster UniversityDr. Gaurav Sharma - Staff psychiatrist working in Nunavut, CanadaThis episode was edited by Dr. Angad Singh - PGY1 psychiatry resident at the University of Toronto Our discussion was structured around four themes:(03:15) - Psychiatry and Economic Incentives(19:33) - Psychiatry and Parenting(28:40) - Biological Psychiatry and its Alternatives(52:05) - Psychiatry and Social ControlIf you enjoyed this episode, consider listening to our episodes about:History of Psychiatry with Dr. David CastleCritical Psychiatry with Dr. Elia Abi-Jaoude and Lucy CostaFor more PsychEd, follow us on Instagram (⁠@psyched.podcast⁠), X (⁠@psychedpodcast⁠), and Facebook (⁠⁠PsychEd Podcast⁠⁠). You can provide feedback by email at ⁠psychedpodcast@gmail.com⁠. For more information, visit our website at ⁠psychedpodcast.org⁠.

Dr. Ethan Short, a practicing psychiatrist and host of the Renegade Psych podcast, joins Dr. Roger McFillin for a bold examination of the crisis in American mental healthcare. From the opioid epidemic that devastated his Kentucky hometown to the broader corruption plaguing psychiatric care, Dr. Short exposes how corporate interests and profit motives have transformed mental healthcare into what critics call a "pill mill" system. This candid conversation explores controversial topics including addiction treatment, pharmaceutical industry influence, the suppression of dissenting medical voices, the anti psychiatry movement & systemic barriers toward informed consent.  A must-listen for anyone concerned about the state of mental healthcare in America.00:00 The Mental Health Crisis: An Overview02:39 Challenging the Status Quo in Psychiatry06:36 The Dichotomy of Biological Psychiatry and Anti-Psychiatry10:40 Understanding Severe Mental Illness: A Complex Perspective12:46 The Role of Medication in Mental Health Treatment17:27 The Uncertainty in Mental Health Knowledge20:04 Common Sense Approaches to Mental Well-Being22:55 Natural Remedies vs. Pharmaceutical Solutions29:31 The Historical Context of Bipolar Disorder31:21 The Marketing of Mental Health Diagnoses34:31 The Interplay of Biology and Environment in Mental Health38:16 The Value of Human Emotions39:31 Cultural Perspectives on Suffering40:29 The Role of Perspective in Recovery43:34 Understanding Substance Abuse44:02 The Opioid Epidemic and Personal Impact51:04 Cultural Attitudes Towards Addiction55:54 Navigating Treatment Options58:40 The Spectrum of Addiction Treatment01:10:05 Financial Incentives in Addiction Treatment01:15:18 Individualized Treatment Approaches in Addiction01:18:54 The Role of Community and Support in Recovery01:19:10 Informed Consent and Patient Autonomy01:21:37 Skepticism Towards Medical Authority01:22:32 The Nuances of Vaccination and Public Health01:25:04 Trust Erosion in Medical Institutions01:28:25 Financial Conflicts of Interest in Healthcare01:30:46 Understanding Virus Mutations and Public Perception01:32:52 The Role of Liability in Pharmaceutical Safety01:35:14 Ethics and Informed Consent in Medical Practice01:38:34 The Importance of Nuanced Discussions in MedicineRenegade Psych YoutubeRenegade Psych X AccountRenegad Psych Instagram RADICALLY GENUINE PODCASTDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here—-----------FREE DOWNLOAD! DISTRESS TOLERANCE SKILLS

ROMA (ITALPRESS) - È stato pubblicato su Biological Psychiatry uno studio che riporta alcuni dati preliminari sulla relazione tra la possibilità di sperimentare episodi depressivi peripartum e la predisposizione genetica a fluttuazioni ormonali. Lo studio, coordinato da Yasmin A. Harrington, è stato realizzato dall'Unità di Psichiatria e Psicobiologia Clinica dell'Ospedale San Raffaele, diretta dal professor Francesco Benedetti. Rappresenta un ulteriore passo in avanti verso la comprensione della depressione peripartum, ancora poco studiata, di cui si stima che soffrano almeno il 15-20% delle donne che diventano madri. col/sat/gtr

¿Qué pasa realmente en tu cuerpo si eliminas el azúcar por completo durante 30 días? En este video te revelaré, paso a paso, los sorprendentes cambios físicos, mentales y emocionales que experimentarás al despedirte del azúcar. Desde una piel más clara y energía constante hasta una mejora significativa en tu salud metabólica y emocional. ¡Prepárate para una transformación que puede cambiar tu vida! Descubre cómo superar cada semana, los beneficios inesperados que obtendrás al final y por qué eliminar el azúcar es una decisión que tu cuerpo y mente agradecerán para siempre. Te damos consejos prácticos para hacer este cambio de manera sencilla y efectiva. ¿Qué aprenderás en este video? -¿Por qué el azúcar afecta tanto a tu salud? -Los cambios semana a semana al dejar el azúcar. -Estrategias efectivas para evitar antojos y mantener la motivación. -Los beneficios inesperados de vivir sin azúcar. ¡Atrévete a dar este paso hacia una vida más saludable y consciente! Sígueme en redes sociales para más contenido: Página web: www.faustoalfaro.com Instagram: https://www.instagram.com/faustoalfaro_/ Twitter: https://twitter.com/Faustoalfaro_ Referencias científicas: - Lustig, R. H., Schmidt, L. A., & Brindis, C. D. (2012). The toxic truth about sugar. Nature, 482(7383), 27–29. - Volkow, N. D., Wang, G. J., Tomasi, D., & Baler, R. D. (2017). The addictive dimensionality of obesity. Biological Psychiatry, 81(10), 859–869. - Seidelmann, S. B., Claggett, B., Cheng, S., Henglin, M., Shah, A., Steffen, L. M., ... & Solomon, S. D. (2018). Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. The Lancet Public Health, 3(9), e419-e428.

La mindfulness, una pratica utile per migliorare la propria consapevolezza e il proprio equilibrio emotivo, agisce sul cervello e ha benefici reali sul controllo del dolore. Questo è quanto evidenzia uno studio pubblicato su Biological Psychiatry, che commentiamo a Obiettivo Salute con prof.ssa Elena Bignami, Ordinario di Anestesia e Rianimazione dell’Università di Parma e Presidente della Società italiana di anestesia, analgesia, rianimazione e terapia intensiva (Siaarti).

This episode is a comprehensive guide for school counselors aiming to improve their engagement with students. Moving beyond traditional worksheets, it provides information about evidence-based, individualized strategies and innovative interventions, particularly those with special needs. The discussion emphasizes the critical evaluation of widely-used resources like those from Teachers Pay Teachers, the necessity of culturally responsive and trauma-informed practices, and aligning interventions with students' IEPs and behavior plans. 00:00 Introduction: The Problem with Worksheets00:43 Rethinking Tools for Special Needs Students02:17 The Appeal and Pitfalls of Worksheets04:36 Personal Story: The Backpack Exercise07:51 The Convenience vs. Effectiveness Debate10:53 Concerns About Unvetted Resources16:13 Focus on Special Student Populations18:29 Individualized Approaches for Special Populations20:21 Culturally Responsive and Trauma-Informed Practices21:40 Practical Sensory-Based Interventions23:27 Art and Movement-Based Techniques27:10 Role-Playing and Therapeutic Games30:22 Recap and Final Thoughts*******References/Resources:Cook, B. G., & Odom, S. L. (2013). Evidence-based practices and implementation science in special education. Exceptional Children, 79(2), 135-144. doi:10.1177/001440291307900201Dunn, W. (2001). The sensations of everyday life: Empirical, theoretical, and pragmatic considerations. American Journal of Occupational Therapy, 55(6), 608-620. doi:10.5014/ajot.55.6.608Hammond, Z. (2015). Culturally responsive teaching and the brain: Promoting authentic engagement and rigor among culturally and linguistically diverse students. Corwin Press.Morgan, P. L., Farkas, G., Tufis, P. A., & Sperling, R. A. (2008). Are reading and behavior problems risk factors for each other? Journal of Learning Disabilities, 41(5), 417-436. doi:10.1177/0022219408321123Reinke, W. M., Herman, K. C., & Sprick, R. (2011). Motivational interviewing for effective classroom management: The classroom check-up. Guilford Press.Rimm-Kaufman, S. E., & Hulleman, C. S. (2015). SEL in the classroom: Identifying and disseminating strategies. The Future of Children, 27(1), 149-172. doi:10.1353/foc.2017.0003Scarpa, A., Williams White, S., & Attwood, T. (2013). CBT for children and adolescents with high-functioning autism spectrum disorders. Guilford Press.Shaywitz, S. E., & Shaywitz, B. A. (2005). Dyslexia (specific reading disability). Biological Psychiatry, 57(11), 1301-1309. doi:10.1016/j.biopsych.2005.01.043Shelton, C., & Archambault, L. (2019). Lessons learned from Teachers Pay Teachers: Exploring the educational value of online marketplaces. Journal of Online Learning Research, 5(1), 35-56. Available from: ResearchGate.*******Hang out in our Facebook groupJump in, ask questions, share your ideas and become a part of the most empowering school counseling group on the planet! (Join us to see if we're right.)Join the School for School Counselors MastermindThe Mastermind is packed with all the things your grad program never taught you IN ADDITION TO unparalleled support and consultation. No more feeling alone, invisible, unappreciated, or like you just don't know what to do next. We've got you!

Die Themen in den Wissensnachrichten: +++ Wegen AfD denken viele Menschen mit Migrationshintergrund übers Wegziehen nach +++ Wie weniger Fledermäuse zu mehr Säuglingssterblichkeit führen +++ Ist es für uns okay, wenn ein Roboter lügt? +++**********Weiterführende Quellen zu dieser Folge:Update ErdeAblehnung, Angst und Abwanderungspläne. Die gesellschaftlichen Folgen des Aufstiegs der AfD/ DeZim, September 2004The economic impacts of ecosystem disruptions: Costs from substituting biological pest control/ Science, 06.09.2024Human perceptions of social robot deception behaviors: an exploratory analysis/ Frontiers in Robotics and AI, 05.092024Mindfulness meditation and placebo modulate distinct multivariate neural signatures to reduce pain/ Biological Psychiatry, 29.08.2024Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: Tiktok und Instagram.

Cheryl Checkers and Dr. Christopher Kye shares their experience working with autistic patients experiencing mental health challenges. Cheryl Checkers is a Licensed Mental Health Counselor, National Board-Certified Counselor, and Certified Autism Spectrum Disorder Clinical Specialist who specializes in working with teens and adults on the autism spectrum and their loved ones. She is the President of the Board of Directors of the National Alliance on Mental Illness of Palm Beach County (NAMI PBC). Cheryl also is a clinical consultant for Florida Atlantic University Center for Autism and Related Disabilities (FAU CARD).She received her Master of Science Degree in Psychology and Mental Health Counseling from Nova Southeastern University. She is both a Licensed Mental Health Counselor and Board-Certified Counselor. She also holds advanced certifications as an Autism Spectrum Disorder Clinical Specialist (ASDCS), a Clinical Anxiety Treatment Professional (CCATP), a Clinical Trauma Professional (CCTP) and a Certified Clinical ADHD Treatment Professional (ADHD-CCSP). Dr. Christopher Kye is a distinguished psychiatrist with over 20 years of experience in caring for individuals from all walks of life. He is deeply committed to incorporating the latest neuroscience insights to enhance the effectiveness of the treatments he offers. Dr. Kye's clinical practice focuses on the needs of children with autism and individuals with mood disorders who have proven resistant to standard treatments. His approach is rooted in a deep understanding of neuroscience, leveraging his research background to enhance patient care. Dr. Kye regularly shares his knowledge on neuropsychiatric topics at various institutions and conferences, including the Center for Autism and Related Disorders at Florida Atlantic University and the National Alliance on Mental Illness. His presentations often focus on the practical application of neuroscience in clinical settings, aiming to improve patient outcomes by better understanding brain-behavior relationships. Dr. Kye is an active member of several professional organizations, including the Society of Biological Psychiatry and the American Academy of Child and Adolescent Psychiatry. His commitment to advancing the field is also evident in his role on the Associate Board of Directors for the National Alliance on Mental Illness in Palm Beach County, where he was honored with the 2015 Exemplary Psychiatrist Award. For more about Cheryl: https://www.cherylcheckers.com/ For more about Dr. Kye: https://www.christopherkyemd.com/ For more about FAU CARD: https://www.fau.edu/education/centersandprograms/card/ FAU CARD's YouTube page: https://www.youtube.com/c/FAUCARD For more about NAMI PBC: https://namipbc.org/ Follow Different Brains on social media: https://twitter.com/diffbrains https://www.facebook.com/different.brains/ https://www.instagram.com/diffbrains/ Check out more episodes of Exploring Different Brains! http://differentbrains.org/category/edb/

Je reçois Pierre Vesperini, philosophe et chercheur au CNRS, pour parler de la question de l'éducation.Le livre d'Isabelle Filliozat, dont il est question dans le Dialogue : https://www.filliozat.net/bibliographie/eduquer-tout-ce-quil-faut-savoir/Pierre Vesperini nous a fait parvenir un ensemble de référence liées à ses propos au long du Dialogue :- Le titre de l'entretien avec Caroline Goldman dans Le Monde :Caroline Goldman, psychologue : « J'ai vu arriver dans mon cabinet des parents sains et structurés, victimes de désinformation sur la parentalité positive », 15 février 2023.- À propos des différences entre le time out de Caroline Goldman et le time out :On peut renvoyer par exemple à la tribune de 280 chercheurs dans Le Monde du 23 mars 2023, intitulée « Le recours à une éducation répressive est défavorable au développement de l'enfant », où on peut lire entre autres ceci :« L'autrice conseille de recourir à sa méthode face aux « transgressions » comme « parler trop », « faire trop de bruit », « râler pour rien », « jeter les petits pots de la chaise haute » ; autant de comportements qui sont pourtant considérés comme normaux chez le jeune enfant en raison de son immaturité. Dans un article publié dans la revue Le Carnet Psy, elle affirme : « La solution tient selon moi en deux mots : le “time out”. (…) Cette méthode est préconisée (…) par le professeur [Alan] Kazdin. » Pourtant, ce dernier exprime ouvertement son désaccord concernant ce qu'elle décrit : « Cela va à l'encontre de tout ce que l'on sait grâce à la recherche sur le sujet » (podcast « Papatriarcat », épisode 101). En effet, les recherches montrent que le time out devrait être un « temps mort » n'excédant pas quatre minutes, comme le précisent Andrew Riley [de l'Oregon Health and Science University] et ses collègues. Le time out n'est pas préconisé pour un très jeune enfant (peu à même de comprendre le sens de cette mesure et n'ayant que peu la capacité de contrôle de ses comportements), ni pour un enfant en pleurs ou anxieux, comme l'ont souligné Alina Morawska et Matthew Sanders [de l'université du Queensland, en Australie]. Il doit aussi être impérativement complété par une attention accrue portée aux comportements constructifs de l'enfant, appelée « renforcement positif », car, à lui seul, le time out a une efficacité limitée. » (je souligne)- La chronique de Yann Moix évoquée : https://www.facebook.com/watch/?v=211269604939836- Olivier Maurel, cité, est le fondateur de l'Observatoire de la violence éducative ordinaire.- Les expériences conduites par Felix Warneken : https://www.youtube.com/watch?v=Z-eU5xZW7cU&t=9shttps://www.youtube.com/watch?v=aHY3m4c8aWE- Sur la durée du time out chez Caroline Goldman « Il ne faut pas hésiter à laisser l'enfant, au-delà de quatre ans, une demi-heure ou plus dans sa chambre. Car l'enjeu, ne l'oublions pas, est de lui faire passer un moment assez inconfortable pour qu'il ne recommence pas… […] S'il n'obéit pas lors de la mise en place de la punition (refus d'y aller, tentation de sortir, vous appeler, taper sur la porte, faire trop de bruit, jeter ses jouets sur le mur, etc.), votre seul argument pour le faire plier à votre ordre doit être un allongement du temps d'exclusion, et rien d'autre (« Tu viens de gagner vingt minutes de plus dans ta chambre. »). » (Goldman, 2020, p. 92 et 94)- Sur le documentaire L'école est finie : https://www.keren-production.fr/films/lappel-et-la-peine/- À propos de l'imagerie cérébrale qui montre que les paroles blessantes activent les mêmes zones que les maltraitances physiques : Anne-Laura van Harmelen et al., "Reduced Medial Prefrontal Cortex Volume in Adults Reporting Childhood Emotional Maltreatment", Biological Psychiatry, 68, 9, 2010, p. 832-838. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Send us a Text Message.Thank you for your audience. Please share and help me grow the channel. The True Psychiatry Podcast is dedicated to reducing the excesses of the field and to bringing psychology back to everyday practice, goals that will ultimately benefit both providers' and patient's quality of life.  Charlie Kurth: Professor of Philosophy at Western Michigan University and a Core Fellow at the Helsinki Collegium for Advanced Studies.  In this Episode Charlie Kurth PhD and I discuss the role of emotions as both, a sensorial experience and a motivational experience and the ethical implications of the Biological Psychiatry paradigm, designed to suppress emotional experiences.

Rodrigo Nardi is a psychiatrist and psychologist. He obtained his psychology degree in the year 2000, and following that, he obtained a certificate in CBT, and a Master's Degree in Clinical Psychology at Universidade Evangélica de Paraná. He obtained his M.D. degree in 2010, and in 2016, he completed his psychiatry residency at Penn State. Altogether, Dr. Nardi has worked as a Mental Health Professional for more than 20 years, covering from individual psychotherapy to inpatient and outpatient psychiatry, substance use treatment, and interventional psychiatry. His passion for teaching and learning has led to the creation of the True Psychiatry Network and the development of a mentoring program designed to address the most frequent challenges related to psychiatric training. *** Thank you for being with us to listen to the podcast and read our articles this year. MIA is funded entirely by reader donations. If you value MIA, please help us continue to survive and grow. To find the Mad in America podcast on your preferred podcast player, click here © Mad in America 2024. Produced by James Moore

Welcome to the Social-Engineer Podcast: The Doctor Is In Series – where we will discuss understandings and developments in the field of psychology.   In today's episode, Chris and Abbie are discussing Irrational Fears & Phobias. They will talk about the similarities, the differences, why some are necessary and how to overcome the ones that aren't. [March 4, 2024]   00:00 - Intro 00:21 - Dr. Abbie Maroño Intro 00:50 - Intro Links -          Social-Engineer.com - http://www.social-engineer.com/ -          Managed Voice Phishing - https://www.social-engineer.com/services/vishing-service/ -          Managed Email Phishing - https://www.social-engineer.com/services/se-phishing-service/ -          Adversarial Simulations - https://www.social-engineer.com/services/social-engineering-penetration-test/ -          Social-Engineer channel on SLACK - https://social-engineering-hq.slack.com/ssb -          CLUTCH - http://www.pro-rock.com/ -          innocentlivesfoundation.org - http://www.innocentlivesfoundation.org/                                                04:55 - The Topic of the Day: Irrational Fears & Phobias  05:09 - Fear vs Phobia 06:33 - Attack of the Lizard People 08:57 - Fear of the Dark 11:28 - In the Heights 13:54 - Might As Well Jump 15:32 - Flight Mode 17:04 - Send in the Clowns 17:32 - Phobias! We Mean It 19:18 - Genetics Squared 21:06 - Beware the Ladybug! 24:35 - Was it a Bunny? 26:09 - Classical Conditioning 27:10 - Little Albert 29:51 - Fear Factor 32:11 - Animal Intuition 33:40 - Mister Ed              34:50 - Fur Babies 36:01 - Learned Response 38:21 - Changing Minds 42:05 - Safety First! 43:21 - Virtual Assistant 44:55 - Words Matter 47:21 - Next Month: David Matsumoto 48:07 - Wrap Up & Outro                              -          www.social-engineer.com -          www.innocentlivesfoundation.org   Find us online: -          Twitter: https://twitter.com/DrAbbieofficial -          LinkedIn: linkedin.com/in/dr-abbie-maroño-phd-35ab2611a -          Instagram: @DoctorAbbieofficial -          Twitter: https://twitter.com/humanhacker -          LinkedIn: linkedin.com/in/christopherhadnagy   References: De Jongh, A., Muris, P., ter Horst, G., Van Zuuren, F., Schoenmakers, N., & Makkes, P. (1999). One-session cognitive treatment of dental phobia: Preparing dental phobics for treatment by restructuring negative cognitions. Behaviour Research and Therapy, 37(S1), S89-S100. Dilger, S., Straube, T., Mentzel, H. J., Fitzek, C., Reichenbach, J. R., Hecht, H., ... & Miltner, W. H. (2003). Brain activation to phobia-related pictures in spider phobic humans: An event-related functional magnetic resonance imaging study. Neuroscience Letters, 348(1), 29-32. Hettema, J. M., Neale, M. C., & Kendler, K. S. (2001). A review and meta-analysis of the genetic epidemiology of anxiety disorders. American Journal of Psychiatry, 158(10), 1568-1578. Kendler, K. S., Myers, J., & Prescott, C. A. (2002). The etiology of phobias: An evaluation of the stress-diathesis model. Archives of General Psychiatry, 59(3), 242-248. Lacey, C., Frampton, C., & Beaglehole, B. (2022). oVRcome – Self-guided virtual reality for specific phobias: A randomised controlled trial. Australian & New Zealand Journal of Psychiatry, 000486742211107. https://doi.org/10.1177/00048674221110779 Mineka, S., & Zinbarg, R. (2006). A contemporary learning theory perspective on the etiology of anxiety disorders: It's not what you thought it was. American Psychologist, 61(1), 10-26. Ollendick, T. H., Ost, L. G., Reuterskiöld, L., Costa, N., Cederlund, R., Sirbu, C., ... & Jarrett, M. A. (2009). One-session treatment of specific phobias in youth: A randomized clinical trial in the United States and Sweden. Journal of Consulting and Clinical Psychology, 77(3), 504-516. Rauch, S. L., Whalen, P. J., Shin, L. M., McInerney, S. C., Macklin, M. L., Lasko, N. B., ... & Pitman, R. K. (2000). Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: A functional MRI study. Biological Psychiatry, 47(9), 769-776. University of York. (2023, February 6). Facing fears in just three hours of therapy could resolve phobias in children. Retrieved from https://www.york.ac.uk/news-and-events/news/2023/research/facing-fears-phobias-children/

In den letzten Jahren hört man immer mehr davon und auch viele Hörer:innen haben sich eine Auseinandersetzung mit diesem Thema gewünscht: Heute geht es um ADHS. Um dieses komplexe Thema verständlicher zu machen, geht es in diesem ersten Teil um die wissenschaftlichen Grundlagen. Sinja und Boris stellen sich die Frage, was ADHS eigentlich genau ist. Dabei beleuchten sie typische Symptome, neurologische Besonderheiten, Folgen, Ursachen und vieles mehr!Wie gefällt dir Verstehen, fühlen, glücklich sein? Erzähle es uns hier.Hintergründe und Studien: Scobel (2023, Dezember 21). Wie #ADHS auch eine Chance sein kann | Gert Scobel [Ganze TV-Folge]. Youtube. Link zum Video Arns, M., Conners, C. K., & Kraemer, H. C. (2013). A Decade of EEG Theta/Beta Ratio Research in ADHD: A Meta-Analysis. Journal of Attention Disorders, 17(5), 374-383. Link zur Studie Hart, H., Raduà, J., Nakao, T., Mataix-Cols, D., & Rubia, K. (2013). Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effects.. JAMA psychiatry, 70 2, 185-98 . Link zur Studie Wu, J., Xiao, H., Sun, H., Zou, L., & Zhu, L. Q. (2012). Role of dopamine receptors in ADHD: a systematic meta-analysis. Molecular neurobiology, 45, 605-620. Link zur Studie Li, D., Sham, P. C., Owen, M. J., & He, L. (2006). Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Human molecular genetics, 15(14), 2276-2284. Link zur Studie Willcutt, E., Doyle, A., Nigg, J., Faraone, S., & Pennington, B. (2005). Validity of the Executive Function Theory of Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review. Biological Psychiatry, 57, 1336-1346. Link zur Studie Ozel-Kizil, E., Kokurcan, A., Aksoy, U., Kanat, B., Sakarya, D., Baştuğ, G., Çolak, B., Altunoz, U., Kırıcı, S., Demirbaş, H., & Oncu, B. (2016). Hyperfocusing as a dimension of adult attention deficit hyperactivity disorder.. Research in developmental disabilities, 59, 351-358 . Link zur StudieGöbel, K., Baumgarten, F., Kuntz, B., Hölling, H., & Schlack, R. (2018). ADHS bei Kindern und Jugendlichen in Deutschland–Querschnittergebnisse aus KiGGS Welle 2 und Trends. Link zur StudieØstergaard, S. D., Dalsgaard, S., Faraone, S. V., Munk-Olsen, T., & Laursen, T. M. (2017). Teenage parenthood and birth rates for individuals with and without attention-deficit/hyperactivity disorder: a nationwide cohort study. Journal of the American Academy of Child & Adolescent Psychiatry, 56(7), 578-584. Link zur Studie Angold, A., Costello, E. J., & Erkanli, A. (1999). Comorbidity. The Journal of Child Psychology and Psychiatry and Allied Disciplines, 40(1), 57-87. Link zur Studie Freitag, C. M., & Retz, W. (Eds.). (2007). ADHS und komorbide Erkrankungen: Neurobiologische Grundlagen und diagnostisch-therapeutische Praxis bei Kindern und Erwachsenen. W. Kohlhammer Verlag Link zum Buch Brikell, I., Kuja‐Halkola, R., & Larsson, H. (2015). Heritability of attention‐deficit hyperactivity disorder in adults. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 168(6), 406-413. Link zur Studie Unsere allgemeinen Datenschutzrichtlinien finden Sie unter https://art19.com/privacy. Die Datenschutzrichtlinien für Kalifornien sind unter https://art19.com/privacy#do-not-sell-my-info abrufbar.

“Traumatic experiences are here to stay, and we shouldn't view them as a prison.” Professor of Neuroscience Rachel Yehuda on how psychedelics may help liberate us from our post-traumatic stress. In this compelling episode, Rachel Yehuda, a renowned expert in post-traumatic stress disorder (PTSD) and trauma effects, challenges the common perceptions surrounding trauma exposure. She explores the distinction between stress and trauma, emphasizing the transformative power of traumatic experiences. Yehuda delves into the physiological and epigenetic changes triggered by trauma, shedding light on the complexities of memory and response. For myriad reasons, trauma is becoming a bigger part of everyday life in our society. Rachel Yehuda, who studies PTSD and the psychological effects of trauma, believes while many of us have become more educated on how traumatic events affect our mental health, we also might be inadvertently convincing ourselves that suffering from mental illness after trauma is inevitable. Yehuda believes trauma is survivable with the right tools and treatments. She is particularly interested in the potential of psychedelics, like MDMA, to facilitate post-traumatic growth and healing. She discusses potential of psychedelics in assisting psychotherapy, allowing individuals to delve deep into their trauma while remaining coherent. She also emphasizes that the success of these therapies depends on the setting, intention, and therapist's expertise. Go Deeper with Big Think: ►Become a Big Think Member Get exclusive access to full interviews, early access to new releases, Big Think merch and more. ►Get Big Think+ for Business Guide, inspire and accelerate leaders at all levels of your company with the biggest minds in business. About Rachel Yehuda: Rachel Yehuda, PhD, Professor of Psychiatry and Neuroscience, is the Director of the Traumatic Stress Studies Division at Icahn School of Medicine, and the Mental Health Patient Care Center Director at the James J. Peters Veterans Affairs Medical Center. Dr. Yehuda has authored more than 300 published papers, chapters, and books in the field of traumatic stress and the neurobiology of PTSD. Her current interests include the study of novel treatments for PTSD, the examination of risk and resilience factors, the study of psychological and biological predictors of treatment response in PTSD, genetic, epigenetic, and molecular biological studies of PTSD and the intergenerational transmission of trauma and PTSD. Her team's research on cortisol and brain function has revolutionized our understanding and treatment of PTSD worldwide. Dr. Yehuda has received many awards in recognition of her work including the Curt Richter Prize in Psychoneuroendocrinology, and the Laufer award from the International Society for Traumatic Stress. She was also awarded the Max Planck Institute for Psychiatry (Munich, Germany) 2004 Guest Professorship in Psychiatry and Neuroscience, and the Marcus Tausk Professorship in Leiden University to honor her accomplishments in the endocrinology of PTSD. Dr. Yehuda received her PhD in Psychology and Neurochemistry and her MS in Biological Psychology from the University of Massachusetts at Amherst and completed her postdoctoral training in Biological Psychiatry in the Psychiatry Department at Yale Medical School. She has an active federally funded clinical and research program that welcomes students and clinicians. disclaimer:- MDMA is currently an investigational drug. Research on psychedelics is being conducted in clinical trials. results have been promising, but it is not yet approved by the food and drug administration. --- Send in a voice message: https://podcasters.spotify.com/pod/show/bigthink/message Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of The Screenagers Podcast, Dr. Ruston focuses on the science behind teen risky decision-making, both online and offline. Dr. Ruston speaks with researchers who shed light on the latest brain science, helping us better understand the biology behind adolescents' decision-making processes. With insights from experts such as psychiatrist Dr. Anna Lembke and psychologist Dr. Lisa Damour, parents will glean practical advice on guiding their children toward wiser decisions and setting fair consequences for rule-breaking. EPISODE NOTES ‍Research References Adolescents' Cognitive Capacity Reaches Adult Levels Prior to Their Psychosocial Maturity: Evidence for a “Maturity Gap” in a Multinational, Cross-Sectional Sample (Law and Human Behavior) Biological substrates of emotional reactivity and regulation in adolescence during an emotional go-nogo task (Biological Psychiatry)   Featured Experts Adriana Galvan, PhD Laurence Steinberg, PhD Lisa Damour, PhD Anna Lambke, MD Time code of the episode 00:04 Introduction and the Complexity of Decision Making 01:23 Understanding the Science Behind Teen Decision Making 02:55 The Role of Emotions in Decision Making 05:05 Real-life Consequences of Rash Decisions 06:17 The Neuroscience of Adolescence 07:38 The Impact of Emotions on Teenagers' Decision Making 10:30 Strategies for Parents to Help Teens Make Wiser Decisions 13:19 The Importance of Setting Limits and Fair Consequences 16:50 Understanding and Empathizing with the Challenges Teens Face 17:50 Conclusion: Encouraging Wise Decision Making

It's time for episode 4: “Zombie Pseudoscience”!You can find a nice (not Substack-generated) transcript of the episode, as well as a music-free remix, here.I know what you've been thinking (I have theory of mind, after all). You've been wondering, “When are they going to discuss Karl Popper? And Imre Lakatos? And goblins?” Well, in this week's episode, we're delighted to finally connect all this “theory of mind deficit” business with the philosophy of pseudoscience.“Zombie Pseudoscience”Autism research focusing on “theory of mind deficits” seems… off. As we've already discussed, it has suffered from repeated failures of replication, and seems to involve constantly shifting goalposts. So at this point, I'm going to go out on a limb and say that the vast majority of this research is bad science.But what makes “theory of mind deficit” research bad science? And is it possible that this body of research has become so bad that it's no longer science at all?We speak with autistic philosopher of science Travis LaCroix (he/him) and neurodivergent philosopher of science Joe Gough (he/him) about the nature of bad science, when bad science becomes pseudoscience, and how bad science can become a zombie that just won't die.Topics Discussed* Quick recap. (00:30) * The “theory of mind deficit” view of autism seemed to become an unfalsifiable theory over time. (02:39) * Why it's important for scientific theories (at least in quantitative research) to be falsifiable. (03:41)* Amelia's sleepy invisible goblin theory. (03:54)* Karl Popper: good scientific theories must be falsifiable. (06:47)* The “theory of mind deficit” view of autism started off as a falsifiable theory, but became unfalsifiable over time. So, it's not exactly like the sleepy invisible goblin theory; it's more analogous to the flat-earth conspiracy theory. (07:07)* Travis's introduction. (10:10)* Travis explains why we can't simply use Popper's falsifiability criterion to explain why “theory of mind deficit” research is bad science. Historical example: the precession of the perihelion of Mercury. (11:06)* Travis explains why Imre Lakatos rejected Popper's falsifiability criterion. According to Lakatos, scientists should not immediately reject a theory when it makes inaccurate predictions. (15:13)* According to Lakatos, a research program contains a “hard core” as well as “auxiliarity hypotheses.” When a research program makes bad predictions, scientists should tinker with their auxiliary hypotheses first, and only abandon the hard core as a last resort. (15:45)* According to Lakatos, it's time to abandon the “hard core” of a research program when the research program degenerates. A research program degenerates when it ceases to make novel predictions, or when it stops making accurate predictions (in spite of tinkering with auxiliary hypotheses). (18:48)* Travis thinks “theory of mind deficit” research is a degenerating research program. (19:47)* Gernsbacher and Yergeau demonstrate that the “theory of mind deficit” view of autism is a bad auxiliary hypothesis. (20:13)* Why Travis thinks “theory of mind deficit” research has degenerated to the point of being pseudoscience . (22:21)* It's often not clear what “theory of mind” means. Different researchers measure it in totally different ways. (24:36)* Joe's introduction. (25:17)* “Theory of mind” in autism research: reasoning explicitly about the mental states of other people disqualifies you from having “good theory of mind.” (26:24)* “Theory of mind” in animal psychology: reasoning explicitly about the mental states of others is essential for having “good theory of mind.” (28:14)* Cross-talk about theory of mind in autism research and in animal psychology dehumanizes autistic people, by creating a (misleading) link between autistic people and non-human animals. (30:02)* “Theory of mind” pops up all over psychology. Is any of this research salvageable? (31:54)* Joe thinks researchers need to get rid of the concept of “theory of mind.” (33:16) * According to Joe, “theory of mind” research isn't much methodologically worse than other types of psychological research. But in autism research focusing on theory of mind deficits, the moral stakes are high—and that makes the normal level of “messiness” in psychology unacceptable. (33:46)* Why Joe thinks that the “theory of mind deficit” view of autism is no longer a real theory; it's more like a bad summary. (34:49)* The origin of that bad summary? Stigma, and perverse institutional incentives. (36:07)* Where Joe thinks “theory of mind” research is going—and where he thinks it should go. (37:54)* Look-ahead to episode 5. (39:08) Sources Mentioned* Karl Popper, Logik der Forschung: Zur Erkenntnistheorie der modernen Naturwissenschaft (1934). Translated into English in 1959 under the title The Logic of Scientific Discovery. http://philotextes.info/spip/IMG/pdf/popper-logic-scientific-discovery.pdf * Imre Lakatos, “Falsification and the Methodology of Scientific Research Programmes” in Criticism and the Growth of Knowledge (1970). Republished in The Methodology of Scientific Research Programmes (Philosophical Papers: Volume 1) (1978). http://www.csun.edu/~vcsoc00i/classes/s497f09/s690s08/Lakatos.pdf* Travis LaCroix, “Autism and the Pseudoscience of Mind”: http://philsci-archive.pitt.edu/22817/* Joe Gough, “The many theories of mind: eliminativism and pluralism in context,” Synthese, Volume 200, Number 4 (2022). https://www.researchgate.net/publication/361904137_The_many_theories_of_mind_eliminativism_and_pluralism_in_context* Papers in which researchers claim that autistic people “hack out” answers to (i.e., cheat on) theory of mind tests, include:* Frith, Happé, and Siddons, “Autism and theory of mind in everyday life,” Social Development, Volume 3 (1994), pp. 108-124.* Happé:* “An advanced test of theory of mind: Understanding of story characters' thoughts and feelings by able autistic, mentally handicapped, and normal children and adults.” Journal of Autism and Developmental Disorders, Volume 24 (1994), pp. 129-154.* “Annotation: Current psychological theories of autism: The “theory of mind” account and rival theories.” Journal of Child Psychology and Psychiatry, and Allied Disciplines, Volume 35 (1994), pp. 215-229. * “The role of age and verbal ability in the theory of mind task performance of subjects with autism.” Child Development, Volume 66 (1995), pp. 843-855.* Baron-Cohen, “The hyper-systemizing, assortative mating theory of autism,” Progress in Neuro-Psychopharmacology and Biological Psychiatry, Volume 30 (2006), 865-872.* For an example of “the logical problem” in animal mind-reading, see Penn and Povinelli, “On the Lack of Evidence that Non-Human Animals Possess Anything Remotely Resembling a ‘Theory of Mind'.” Philosophical Transactions of the Royal Society, B 362 (2007), pp. 731-744.* Joe says, “Much higher stakes means a higher evidential bar, that seems like just part of doing science responsibly.” For more on this idea, I suggest reading work by the philosopher of science Heather Douglas. For example, see her paper “The Role of Values in Expert Reasoning,” Public Affairs Quarterly, Volume 22, Number 1 (January 2008).CreditsHosting, Research, Fact-Checking, Script-Editing: Amelia Hicks and Joanna LawsonGuests: Travis LaCroix and Joe GoughMusic and Audio Production: Amelia HicksThank-YousMany thanks to Travis LaCroix and Joe Gough for speaking with us about bad science, pseudoscience, and “theory of mind deficit” research! Be sure to take a look at Travis's new paper about autism pseudoscience and theory of mind, as well as other neat projects associated with his new grant, titled “Philosophy on the Spectrum”: https://autphi.github.io/about/. Also, over the next three years, Joe will be researching legal and medical assessments of decision-making capacity, and how those assessments misfire for neurodivergent and cognitively disabled people—I'm really looking forward to seeing the work that comes out of that post-doc.And thanks to the Marc Sanders Foundation and the Templeton Foundation for their support of the show. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit neurodiving.substack.com

If there was one thing you think society should talk more about, what would it be? “The grieving brain: the surprising science of how we learn from Love and loss ”__________Mary-Frances O'Connor PhD is one of the happiest people you'll ever meet and yet, she talks about grief all day, every day. Whilst many of you long-time listeners here on the podcast know I'm not shy when it comes to talking about death and grief, I wanted to learn more from Mary-Frances and get her take on a subject she's studied for more than 24 years. Mary-Frances is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab, which investigates the effects of grief on the brain and the body. She earned a doctorate from the University of Arizona and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for , she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, the New York Times, and The Washington Post. She recently released a book on many of her findings:- The Grieving Brain: The surprising science of how we learn from love and loss - where she shares groundbreaking discoveries about what happens in our brain when we grieve, providing a new paradigm for understanding love, loss, and learning. _______For more information about Mary-Frances, check out these places;-Website: https://maryfrancesoconnor.org/Her Book: The Grieving BrainInstagram: Mary-Frances Linkedin: https://www.linkedin.com/in/maryfrancesoconnor/Head to michellejcox.com for more information about the ONE QUESTION podcast, your host or today's guestsConnect with Michelle on Linkedin here:- @MichelleJCoxConnect with Michelle on Instagram here:- @michellejcoxConnect with Michelle on Facebook here - @michellejcoxAND, if you have a burning topic you'd love people to talk more about, or know someone who'd be great to come on the One Question podcast, please get in touch;- hello@michellejcox.com

Many treatments in psychiatry have proven efficacy and known side effects. However, clear, understandable and scientific explanations of their actions are thin on the ground. Exploration of drug actions at the fundamental level of the receptor can provide valuable insights for the treating physician. The BJPsych Advances Biological Psychiatry special issue aims to provide theoretical underpinnings that might assist clinicians in making decisions particularly about doses of antipsychotics - including partial agonists - either alone or in combinations. In this podcast, Dr Oliver Gale-Grant and author Professor John Cookson discuss his recent articles in the BJPsych Advances Biological Psychiatry special issue. Read the articles at: https://www.cambridge.org/core/journals/bjpsych-advances/bjpsych-advances-biological-psychiatry-special-issue Follow us on Twitter @TheBJPsych #BJPAdvances Disclaimer: BJPsych Advances is not responsible for statements made by podcast contributors. Unless so stated, the content of this podcast does not necessarily reflect the views of the Editor-in-Chief or the Royal College of Psychiatrists

Related to this podcast's interests in data sharing, this week Jess and Sara talk about common data elements initiatives. These are movements that are hoping to get all of the researchers in the same field or subfield to agree to a given set of assessments, measures, procedures, and/or reporting metrics (Think: Everyone who measures mother's education would ask the same stem question with the same eight category responses, which would be coded and reported in the same way).  We'll talk about different types of initiatives, the reasons why proponents think it's a great idea, and what major concerns might come up. Sara also gives us a mini lecture introducing genome-wide association studies. Trust us, it's related!  In this episode, we talk about:  The NIH Common Data Elements Program: https://heal.nih.gov/data/common-data-elements  NIH Common Measures website: https://www.phenxtoolkit.org/  A paper about the NIMH common data elements: Barch, D. M., Gotlib, I. H., Bilder, R. M., Pine, D. S., Smoller, J. W., Brown, C. H., ... & Farber, G. K. (2016). Common measures for National Institute of Mental Health funded research. Biological Psychiatry, 79(12), e91-e96. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968690/ What's the difference between common measures and common metrics:  de Beurs, E., Boehnke, J. R., & Fried, E. I. (2022). Common measures or common metrics? A plea to harmonize measurement results. Clinical Psychology & Psychotherapy, 29(5), 1755-1767. Paper describing the openly available Project KIDS data: Van Dijk, W., Norris, C. U., Al Otaiba, S., Schatschneider, C., & Hart, S. A. (2022). Exploring individual differences in response to reading intervention: Data from Project KIDS (Kids and Individual Differences in Schools). Journal of Open Psychology Data, 10(1). Educational attainment GWAS paper data harmonization appendix: https://static-content.springer.com/esm/art%3A10.1038%2Fs41588-022-01016-z/MediaObjects/41588_2022_1016_MOESM1_ESM.pdf   Connect with the podcast on twitter @within_between, or email us letters about developmental science at withinandbetweenpod@gmail.com. More episodes and podcast information at WithinandBetweenPod.com. Follow Dr. Hart on twitter @Saraannhart Follow Dr. Logan on twitter @Jarlogan. Our theme music was composed by Jason Flowers. Our logo was created by Nathan Archer. Recorded July 9, 2023.

The Psych Review is back in force in 2023, with the entire cast returning for what is shaping up to be an epic season six. In the first episode of this season Dave digs into the largest ever depression focussed genome wide association study and discovers some new significant genetic loci for depression, and Alanna talks us through the recent Therapeutic Goods Administration approval of Psychedelic Assisted Therapies in Australia - a world first.The references for this episode are:Dave: Mitchell, B. L., Campos, A. I., Whiteman, D. C., Olsen, C. M., Gordon, S. D., Walker, A. J., ... & Byrne, E. M. (2022). The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes. Biological Psychiatry, 92(3), 227-235.Alanna: Williams, M. L., Korevaar, D., Harvey, R., Fitzgerald, P. B., Liknaitzky, P., O'Carroll, S., Puspanathan, P., Ross, M., Strauss, N., & Bennett-Levy, J. (2021). Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead. Frontiers in psychiatry, 12, 737738. https://doi.org/10.3389/fpsyt.2021.737738The Psych Review was brought to you by Call to Mind, a telepsychiatry service that you can learn more about at www.calltomind.com.au. The original music in our podcast was provided by the very talented John Badgery, and our logo was designed by the creative genius of Naz.

Mary-Frances O'Connor is my special guest in this episode. I devoured her book, The Grieving Brain: The Surprising Science of How We Learn from Love and Loss last year and knew I needed to have a conversation with the author on this show. I'm grateful to share that late last year, I had the honor of sitting down with Mary-Frances to explore the fascinating work she has been doing studying the Grieving Brain. I'm 100% confident you will learn so much and appreciate the warmth and wisdom she brings to this conversation. EPISODE RESOURCES:Mary-Frances O'Connor is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab, which investigates the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, the New York Times, and The Washington Post.I HIGHLY RECOMMEND buying her book, The Grieving Brain here at Amazon or any major booksellers. You can also learn more about her and her work by visiting her website: www.maryfrancesoconnor.orgJUMP STRAIGHT INTO:(13:46) – Explains shift from understanding grief effect on physiology to effect on the brain(21:-00) – Mary-Frances explains our need for attachment and security and what happens when we lose that relationship.(36:45) – Explains how understanding how the brain maps our relationships and why each grief journey is unique (43:00) - Explains while it's common for us to think about the shoulda, coulda, wouldas in loss, rumination is actually a form of avoidance. She offers some alternative ways to consider the loss.NEW MERCH ALERTYou asked, I answered. I finally created some GSB Podcast merch from tees to hoodies to coffee mugs, journals and stickers. Head over to the Grief Happens Shop at www.lisakeefauver.com/griefhappensshop 3 WAYS TO STAY CONNECTED SUBSCRIBE TO THE PODCAST on your favorite platform so you don't miss an episode. If you love the show, I'd love to invite you to leave a rating and write a review.INVITE ME TO YOUR INBOX to get behind-the-scenes on the podcast and all the grief support offered by our host, Lisa Keefauver, by signing up for her Not-So-Regular Newsletter at lisakeefauver.com/newsletter.IF YOU'RE FEELING SOCIAL, you can find her on all your favorite social channels too. @lisakeefauvermsw on Instagram, LinkedIn, Facebook, YouTube and TikTok. Check out her tweets @lisakeefauver Hosted on Acast. See acast.com/privacy for more information.

Estudo americano publicado no Biological Psychiatry concluiu, através de ressonâncias magnéticas, que o cérebro dos adolescentes envelheceu com a pandemia

Mary-Frances O'Connor, PhD, is author of The Grieving Brain: The Surprising Science of How We Learn from Love and Loss. She is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab, which investigates the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for Psychoneuroimmunology, she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, the New York Times, and The Washington Post. Having grown up in Montana, she now lives in Tucson, Arizona. For more information go to https://www.maryfrancesoconnor.com/ You can find Mary-Frances online... Website Instagram Twitter Facebook LinkedIn Originally published 15/12/22

I have been following the research of Dr Mary-Frances O'Connor for almost a decade now, so I was absolutely delighted when she published her book ‘The Grieving Brain' last year. I am always hungry to learn about grief and specifically, what can the science tell us about how to make sure we are supporting the bereaved in the most compassionate and effective way possible. This book affirmed a lot of what I experience in clinical practice and also taught me more about the grieving process. Loss of a loved one is something everyone experiences, and for as long as humans have existed, we have struggled when a loved one dies. Poets and playwrights have written about the dark cloak of grief, the deep yearning, and devastating heartache of loss. But until now, we have had little scientific perspective on this universal experience. In THE GRIEVING BRAIN: The Surprising Science of How We Learn from Love and Loss (HarperOne; February 1, 2022; Hardcover) renowned grief expert, neuroscientist, and psychologist Mary-Frances O'Connor, Ph.D., shares groundbreaking discoveries about what happens in our brain when we grieve, providing a new paradigm for understanding love, loss, and learning. In The Grieving Brain, O'Connor, who has devoted decades to researching the effects of grief on the brain, reveals a fascinating new window into one of the hallmark experiences of being human. She makes cutting-edge neuroscience accessible and guides us through how we encode love and grief. With love, our neurons help us form attachments to others; but, with loss, our brain must come to terms with where our loved ones went, and how to imagine a future that encompasses their absence. Significantly, O'Connor debunks Kubler-Ross' enduring idea of the “Five Stages of Grief” and sets a new paradigm for understanding grief on a neurological level. -More- Based on O'Connor's own trailblazing neuroimaging work, research in the field, and real-life stories, The Grieving Brain brings together accessible science and practical knowledge that provides a more nuanced understanding of what happens when we grieve and how to navigate loss with more ease and grace. The Grieving Brain addresses: • Why it's so hard to understand that a loved one has died and is gone forever • Why grief causes so many emotions—sadness, anger, blame, guilt, and yearning • Why grieving takes so long • What happens in the brain during grief • The distinction between grief and complicated grief • Why we ruminate so much after we lose a loved one • How we go about restoring a meaningful life while grieving. Ground-breaking, fascinating and accessible, The Grieving Brain is essential reading for everyone who's lost someone and for anyone looking for a way to heal. ABOUT THE AUTHOR: Mary-Frances O'Connor, PhD is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab, which investigates the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for Psychoneuroimmunology, she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, the New York Times, and The Washington Post. Having grown up in Montana, she now lives in Tucson, Arizona. For more information go to https://www.maryfrancesoconnor.com/ THE GRIEVING BRAIN The Surprising Science of How We Learn from Love and Loss By Mary-Frances O'Connor HarperOne, an imprint of HarperCollins Publishers Hardcover | ISBN: 9780062946232 www.maryfrancesoconnor.com/book Twitter: @doctormfo FaceBook: @maryfranceso Instagram: @doctormfoconnor LinkedIn: Mary-Frances O'Connor

What are the 6 components of Wisdom? Why is wisdom important for relationships? We answer all these and more on today's episode of It Starts With Attraction!Today's Guest: Dilip Jeste, M.D.Dilip V. Jeste, M.D. is Former Senior Associate Dean for Healthy Aging and Senior Care and Distinguished Professor of Psychiatry and Neurosciences at University of California San Diego. He obtained his medical education in Pune, and psychiatry training in Mumbai, India. In the US, he completed psychiatry residency at Cornell, and Neurology residency at George Washington University. He was a research fellow, and later, Chief of the Units on Movement Disorders and Dementias at the National Institute of Mental Health (NIMH) before joining UC San Diego where he retired in July 2022.He started a Geriatric Psychiatry program from scratch at UC San Diego; it became one of the largest Geriatric Psychiatry Divisions in the world. Dr. Jeste has been Principal Investigator on a number of research and training grants. His main areas of research include schizophrenia, neuropsychiatric interventions, and successful aging. He has published 14 books, including his most recent book entitled “Wiser”, over 750+ articles in peer-reviewed journals, and 160+ invited book chapters. He was listed in “The Best Doctors in America” and in the Institute of Scientific Information list of the “world's most cited authors” comprising fewer than 0.5% percent of all publishing researchers of the previous two decades. Dr. Jeste has received many awards including NIMH's MERIT Award; Commendation for Dedicated Service from the Veterans Affairs; and awards from Society of Biological Psychiatry; APA; Institute of Living; American College of International Physicians; National Alliance on Mental Illness; National Alliance for Research in Schizophrenia and Affective Disorders; American College of Psychiatrists; International Psychogeriatric Association; Universities of Pennsylvania, Pittsburgh, Cincinnati, and Maryland, and Cornell. He has also received Honorary Fellowship, the highest honor it bestows, from UK's Royal College of Psychiatrists; and Honorary Professorship from Universidad Peruana Cayetano Heredia, Lima, Peru.Links Mentioned:Book: amazon.com/Wiser-Scientific-Roots-Wisdom-Compassion/dp/1683644638Website: dilipjestemd.comWebsite: aging.ucsd.eduTedMed: tedmed.com/speakers/show?id=526374Your Host: Kimberly Beam Holmes, Expert in Self-Improvement and RelationshipsKimberly Beam Holmes has applied her master's degree in psychology for over ten years, acting as the CEO of Marriage Helper & CEO and Creator of PIES University, being a wife and mother herself, and researching how attraction affects relationships. Her videos, podcasts, and following reach over 200,000 people a month who are making changes and becoming the best they can be.Website: www.kimberlybeamholmes.comTake the Attraction AssessmentThanks for listening!Connect on Instagram: @kimberlybeamholmesBe sure to SUBSCRIBE to the podcast and leave a review!Visit marriagehelper.com/drjoe to sign up for the in-person workshop on November 18-20

Dr. John Krystal — All Things Ketamine, The Most Comprehensive Podcast Episode Ever | Brought to you by Athletic Greens all-in-one nutritional supplement, Helix Sleep premium mattresses, and Allform premium, modular furniture. Dr. John Krystal is the Robert L. McNeil, Jr., Professor of Translational Research; Professor of Psychiatry, Neuroscience, and Psychology; Chair of the Department of Psychiatry at Yale University; and Chief of Psychiatry and Behavioral Health at Yale-New Haven Hospital.Dr. Krystal is a leading expert in the areas of alcoholism, post-traumatic stress disorder, schizophrenia, and depression. His work links psychopharmacology, neuroimaging, molecular genetics, and computational neuroscience to study the neurobiology and treatment of these disorders. He is best known for leading the discovery of the rapid antidepressant effects of ketamine in depressed patients.He directs/co-directs the Yale Center for Clinical Investigation (CTSA), NIAAA Center for the Translational Neuroscience of Alcoholism, and Clinical Neuroscience Division of the National Center for PTSD (VA).Dr. Krystal is a member of the U.S. National Academy of Medicine; co-director of the Neuroscience Forum of the U.S. National Academies of Sciences, Engineering, and Medicine; Fellow of the American Association for the Advancement of Science (AAAS); and editor of Biological Psychiatry, one of the most selective and highly cited journals in the field of psychiatric neuroscience.He is the co-founder and Chief Scientific Advisor of Freedom Biosciences, a clinical-stage biotechnology platform developing next-generation ketamine and psychedelic therapeutics that recently emerged from stealth in August 2022.ONE VERY IMPORTANT DISCLAIMER: I'm not a doctor, nor do I play one on the Internet. None of the content in this podcast constitutes medical advice or should be construed as a recommendation to use ketamine or psychedelics. There are psychological, physical, and sometimes legal risks with such usage. Please consult your doctor before considering anything we discuss in this episode.Please enjoy!*This episode is brought to you by Helix Sleep! Helix was selected as the #1 overall mattress of 2020 by GQ magazine, Wired, Apartment Therapy, and many others. With Helix, there's a specific mattress to meet each and every body's unique comfort needs. Just take their quiz—only two minutes to complete—that matches your body type and sleep preferences to the perfect mattress for you. They have a 10-year warranty, and you get to try it out for a hundred nights, risk-free. They'll even pick it up from you if you don't love it. And now, Helix is offering up to 200 dollars off all mattress orders plus two free pillows at HelixSleep.com/Tim.*This episode is also brought to you by Athletic Greens. I get asked all the time, “If you could use only one supplement, what would it be?” My answer is usually AG1 by Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system. Right now, Athletic Greens is offering you their Vitamin D Liquid Formula free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit AthleticGreens.com/Tim to claim this special offer today and receive the free Vitamin D Liquid Formula (and five free travel packs) with your first subscription purchase! That's up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.*This episode is also brought to you by Allform! If you've been listening to the podcast for a while, you've probably heard me talk about Helix Sleep mattresses, which I've been using since 2017. They also launched a company called Allform that makes premium, customizable sofas and chairs shipped right to your door—at a fraction of the cost of traditional stores. You can pick your fabric (and they're all spill, stain, and scratch resistant), the sofa color, the color of the legs, and the sofa size and shape to make sure it's perfect for you and your home.Allform arrives in just 3–7 days, and you can assemble it yourself in a few minutes—no tools needed. To find your perfect sofa and receive 20% off all orders, check out Allform.com/Tim.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

------------------Support the channel------------ Patreon: https://www.patreon.com/thedissenter PayPal: paypal.me/thedissenter PayPal Subscription 1 Dollar: https://tinyurl.com/yb3acuuy PayPal Subscription 3 Dollars: https://tinyurl.com/ybn6bg9l PayPal Subscription 5 Dollars: https://tinyurl.com/ycmr9gpz PayPal Subscription 10 Dollars: https://tinyurl.com/y9r3fc9m PayPal Subscription 20 Dollars: https://tinyurl.com/y95uvkao This show is sponsored by Enlites, Learning & Development done differently. Check the website here: http://enlites.com/ Dr. Moshe Bar is Head of the Cognitive Neuroscience Lab at the Multidisciplinary Brain Research Center at Bar-Ilan University. He does research in Cognitive Neuroscience, Biological Psychiatry, NeuroImaging, and Learning and Memory. He is the author of Mindwandering: How Your Constant Mental Drift Can Improve Your Mood and Boost Your Creativity. In this episode, we focus on Mindwandering. Topics include: the default mode network; how thoughts get associated; good and bad types of mindwandering; the relationship between mindwandering and mental health, with the example of schizophrenia; associative thinking and preferences; what we mindwander about; our sense of self; inner speech; Dr. Bar's work on visual cognition, and the driller vs. hairdryer experiment; the inevitability of expectations, and how to deal with them; first impressions about other people; the relationship between states of mind and personality; immersion (in the modern industrial world); and if it is possible to deliberately change states of mind. -- A HUGE THANK YOU TO MY PATRONS/SUPPORTERS: KARIN LIETZCKE, ANN BLANCHETTE, PER HELGE LARSEN, LAU GUERREIRO, JERRY MULLER, HANS FREDRIK SUNDE, BERNARDO SEIXAS, HERBERT GINTIS, RUTGER VOS, RICARDO VLADIMIRO, CRAIG HEALY, OLAF ALEX, PHILIP KURIAN, JONATHAN VISSER, JAKOB KLINKBY, ADAM KESSEL, MATTHEW WHITINGBIRD, ARNAUD WOLFF, TIM HOLLOSY, HENRIK AHLENIUS, JOHN CONNORS, PAULINA BARREN, FILIP FORS CONNOLLY, DAN DEMETRIOU, ROBERT WINDHAGER, RUI INACIO, ARTHUR KOH, ZOOP, MARCO NEVES, COLIN HOLBROOK, SUSAN PINKER, PABLO SANTURBANO, SIMON COLUMBUS, PHIL KAVANAGH, JORGE ESPINHA, CORY CLARK, MARK BLYTH, ROBERTO INGUANZO, MIKKEL STORMYR, ERIC NEURMANN, SAMUEL ANDREEFF, FRANCIS FORDE, TIAGO NUNES, BERNARD HUGUENEY, ALEXANDER DANNBAUER, FERGAL CUSSEN, YEVHEN BODRENKO, HAL HERZOG, NUNO MACHADO, DON ROSS, JONATHAN LEIBRANT, JOÃO LINHARES, OZLEM BULUT, NATHAN NGUYEN, STANTON T, SAMUEL CORREA, ERIK HAINES, MARK SMITH, J.W., JOÃO EIRA, TOM HUMMEL, SARDUS FRANCE, DAVID SLOAN WILSON, YACILA DEZA-ARAUJO, IDAN SOLON, ROMAIN ROCH, DMITRY GRIGORYEV, TOM ROTH, DIEGO LONDOÑO CORREA, YANICK PUNTER, ADANER USMANI, CHARLOTTE BLEASE, NICOLE BARBARO, ADAM HUNT, PAWEL OSTASZEWSKI, AL ORTIZ, NELLEKE BAK, KATHRINE AND PATRICK TOBIN, GUY MADISON, GARY G HELLMANN, SAIMA AFZAL, ADRIAN JAEGGI, NICK GOLDEN, PAULO TOLENTINO, JOÃO BARBOSA, JULIAN PRICE, EDWARD HALL, HEDIN BRØNNER, DOUGLAS P. FRY, FRANCA BORTOLOTTI, GABRIEL PONS CORTÈS, URSULA LITZCKE, DENISE COOK, SCOTT, ZACHARY FISH, TIM DUFFY, TRADERINNYC, TODD SHACKELFORD, AND SUNNY SMITH! A SPECIAL THANKS TO MY PRODUCERS, YZAR WEHBE, JIM FRANK, ŁUKASZ STAFINIAK, IAN GILLIGAN, LUIS CAYETANO, TOM VANEGDOM, CURTIS DIXON, BENEDIKT MUELLER, VEGA GIDEY, THOMAS TRUMBLE, AND NUNO ELDER! AND TO MY EXECUTIVE PRODUCERS, MICHAL RUSIECKI, ROSEY, JAMES PRATT, MATTHEW LAVENDER, SERGIU CODREANU, AND BOGDAN KANIVETS!

On the Mad in America podcast this week, we hear from the co-authors of a paper published in the journal Ethical Human Psychology and Psychiatry which documents the mass murder of a quarter of a million people, mostly diagnosed as “schizophrenic” in Europe during the Second World War. Later, we hear from Dr. Jeffrey Masson, who is an author and a scholar of Sanskrit and psychoanalysis. But first, we talk with professor of psychology John Read. Regular visitors to Mad in America will know of John's work. For those that don't know, John worked for nearly 20 years as a clinical psychologist and manager of mental health services in the UK and the USA, before joining the University of Auckland, New Zealand, in 1994, where he worked until 2013. He has served as director of the clinical psychology professional graduate programmes at both Auckland and, more recently, the University of Liverpool. He currently works in the School of Psychology at the University of East London. John has many research interests, including critical appraisals of the use of psychiatric drugs and electroconvulsive therapy. Jeffrey Masson has had a fascinating career in which he studied Sanskrit and psychoanalysis and became director of the Sigmund Freud archives. A prolific author, he has written more than 30 books and has become an advocate for animal rights. He is currently an Honorary Fellow in the Department of Philosophy at the University of Auckland in New Zealand. We discuss how John and Jeffrey came to write a paper which examines a grim period in psychiatric history.

Dr. Fred Moss is a holistic Physician, Restorative Coach, Podcaster, Psychiatrist Expert, Witness at Welcome to Humanity with Dr. Fred Moss. Dr. Moss arrived on Earth on March 01, 1958 and from that very second has been earmarked to be a healer. The family he was born into, was in chaos, and in many ways was counting on his arrival to bring health and wellness back into balance. Little Freddy had his hands full and over the next 6 decades, he has made it his business to bring healing to the world around him, not only to his family and friends, but to the community and world at large, what a journey it has been.   Questions Could tell us in your own words a little bit about your journey? Could you share with us as an organization, maybe one or two things that you can do as leadership in an organization or putting in place some form of programme to support team members where mental health is concerned in order to strengthen the customer experience? If there was one thing to do immediately to assist ourselves when we're feeling out of balance. What would you suggest that one thing would be? Could you share with us what's the one online resource, tool, website or app that you absolutely can't live without in your business? Could you also share with us and I'm sure you've read many, many books across your lifespan, especially in the field that you are in, but maybe one or two that have had a great impact on you, it could be a one that you read a very long time ago, or even one you've read recently, that you'd like to share with our listeners? Could you also share our listeners what's one thing that's going on in your life right now that you're really excited about, either something you're working on to develop yourself or your people? Where can listeners find you online? Do you have a quote or a saying that during times of adversity or challenge you'll tend to revert to this quote? It kind of helps to get you back on track if for any reason you get derailed or get off track. Do you have one of those?   Highlights   Dr. Moss' Journey   Me: I know we read a little bit about your journey. And I didn't read your entire bio. But if you could tell us in your own words a little bit about your journey, I know your bio, the part that I did read did indicate that you have been doing quite a bit of work since you landed on Earth. And so, could you just share with our listeners a little bit about how you got to where you are today?   Dr. Moss shared that it has been a long strange trip. It's been a little over 64 years now and young at heart for sure. And there's lots of work to do. He arrived on that March 01, 1958 with the whole idea of being counted on to bring joy and pleasure and love and reconnection to that family. And for the first couple years, he probably did pretty good until his brothers got annoyed and irritated with him, he had two brothers, still do who 10 and 14 years older than him. And they taught him how to be precocious. They taught him how to read and write and do math, even before he arrived in kindergarten. Because when he arrived there, he was ahead of the class, he was doing things that most of the kindergarteners didn't want to do, he was like interested in flashcards and books and stuff like that.   He was also bored, so he became a class clown, there's nobody in elementary school, no teacher he ever had who certainly ever forgot him as a student. Because what he was really interested in more than anything, he thought school was going to show him how to communicate, he loved the way that his parents and his brothers communicated with each other, he could just watch him from the playpen. And he knew that there was something special in the world of sharing ideas with each other and he really wanted to learn how to do that become a master of communication. But low and behold, elementary school was not a place to learn that and he thought, “Oh, maybe the bigger kids, Junior High.” And when he got there, it was even worse. He thought, “Okay, High School.” and then that would be even worse, all you had to do is sit down and regurgitate what the teacher said, and that they would call you a good student and move you ahead. And he just thought that was so absurd.   Eventually, he went to college and with the whole idea again, he went to the best college he could possibly think because he loved their football helmets and that was a University of Michigan. And he went there and again, was kind of disillusioned with the idea that what he really had to do was just follow what the professor said and say whatever they wanted him to say and then pass, that wasn't open discourse and that's what I really wanted. So, he dropped out of college and he did what any self-respecting American dropout would do in the late 70s. He had boarded a Greyhound bus and went all the way to Berkeley, California so that he could learn, just figuring out who he was. He had a great summer in Berkeley, but realized he didn't have a job and not much of a future.   So, his mom convinced him to come back and try school one more time. He came back, there was a new field that was just growing, you might have heard of it, it's called Computer Science and the only computer that was there in Michigan was happened to be at the University of Michigan. So, it was a two-acre facility, he spent his day and night there, pulling up batch cards like punch cards and then hoping that the batch would run and he did that for a little while until he realized that wasn't going to work, so he dropped out again. This is when the story starts getting interesting because in 1980 when he dropped out, his mom, again convinced him that she should probably get a job. And I thought, yeah, making some money so he could buy a car so he could go around the country and figure out what his life is about made some sense.   So, he started working at a state hospital for adolescent psychiatry, State House Psychiatric Hospital for adolescent boys. And that's where really his journey in some ways with this whole idea of mental health began.   On January 05, 1980, he began that job and he was a communicator, he knew that he could communicate with these kids and then when they communicated and connected as human beings, well, healing took place in all directions, not just for them but for him as well and maybe even for the people around them. Like treating these people like they were just people and not sick kids who are defective or afflicted but just people just like him who don't really know what to do next, and aren't really sure what their next step was, and really just acknowledging them for being human.   He really, really strongly learned that communication and connection was at the heart of all healing of all conditions. The thing he really disrespected though, was the way psychiatry was dealing with these kids. He hated psychiatry, he hated that they would call the psychiatrist and they would come by and interview the child for three seconds. So, they'd say like, “Johnny's up too late.” or “Timmy and Tony got in a fight.” They'd interview the kid for 3 seconds, and then interview them for like 5 seconds and then take out their pen and write an order. And then they have to go haul the kid into the quiet room and hold them down against his will and then fill his hip up with adult grade anti-psychotic injectable medication. And if this puts him out of his misery for the next 12 or 24 hours, they'd somehow call that a success. He found that to be so barbaric and it's still going on in our world today, if you need to know. It's going on every single day in many different hospitals around the world.   But he just decided that communication and connection really were what he wanted to be a stand for. And he went back to school solely to become a psychiatrist so that he could bring communication back to that field because he saw the opportunity that psychiatry had to really make a difference in the world that they did that.   Over the next 13 years, he completed his degree and completed his residency and completed his fellowship. And low and behold, he graduated as a psychiatrist from a great medical school and a great residency. And there he was, the truth is that psychiatry had gone through a significant change at that time and began medicating people. This whole idea of diagnosing and medicating and Biological Psychiatry falls on the heels of a drug called Prozac. And Prozac had been introduced in 1987 while he was in training, and now he too was becoming a psycho pharmacologist. Now, you can guess that there was some soul sacrifice there, there was a massive heart ache because he didn't want to prescribe medicine, he didn't want to diagnose people, he went into the field so he wouldn't have to do that.   But there he was actually living a life that was inconsistent to who he was. And over the next 15 years, he did his best to bring communication there but more and more, he was being contracted and constricted away from the psychiatric field. In 2006, he decided that he would finally start taking people off of medicine, he took some of his low risk people off of medicine, and they just got way better, reliably better. As soon as he took the medicine away, their diagnosis often disappeared. And he thought he was onto something like maybe the medicines actually perpetuate to conditions. Maybe in fact the medicines actually worsen or cause the conditions at times. Now, this made him really angry, and he didn't know exactly how to manage it, but over time, and it's been, what, 15, 16 years since 2006, he's really learned how to really get respect for not medicating, not diagnosing and then they call him the un-doctor, un-medicated, un-diagnosing, and then un-doctornating people. Really getting that if you're having a miserable time as a human, if you're uncomfortable, anxious, fearful, depressed, sad, confused, scattered, any of those things, it's entirely okay.   And it's part of being a human, to be highly uncomfortable at times, to be miserable at times is okay. That doesn't mean there's something wrong with you. We don't blame a log for burning in the fire, if you put a log into fire, it's going to burn, if you put a human on this world, we're going to be uncomfortable. And we start really looking at that and he's back to getting the connection is at the heart of all healing.   So, he created a company called Welcome to Humanity in 2015. And that was self-explanatory, all things human are okay. The possibility of seeing all people for who they are and who they're not is okay. The possibility of accepting and even having some compassion and forgiveness for the misery that we all feel is all okay. And they started really communicating and connecting as a healer, instead of as a doctor that he had been prior to that.   After Welcome to Humanity, several other different things have sprouted, there was global madness where he was going to go around the world like Anthony Bourdain, and really see that psychiatry is different and the whole idea of mental health is different in Jamaica. And it's different everywhere. It's like what's sick in Jamaica isn't the same as what's sick in California. And so, it can't really be if you have a broken arm in Jamaica, you're going to have that same broken arm if you fly to California, but that's not true of mental health and mental illness.   And so, the idea that it's variable, meaning that it's transformable, meaning that we can alter this whole idea of what mental health and mental illnesses through conversation. Meaning that we can actually make a difference with people without having to put them on a couch 4 times a week or send them to Tibet or India. Or even give them a bunch of ganja, those aren't the only ways to find peace and we can find peace by recognizing that each of us are in this together.   The true voice technology is his most recent finding, after doing the creative eight, the creative eight really took advantage of the art, music, dancing, singing, drama, cooking, writing, gardening, all the creative acts in life can really lead to a reduction of the symptomology. And the Find Your True Voice technology, his most recent book, which he can offer to listeners, actually, is a technology that takes a deep dive into finding our authenticity in the face of any world experience and then speaking our exact truth, like what's really important to us, because you've probably noticed, a lot of people are no longer speaking their truth and they're just saying things that they don't even mean, or not saying things at all, because they're afraid they're going to be dismissed or discounted or censored or cancelled or hurt.   And he thinks in these difficult times in the world, more than anything, we really have to count on people to speak their true voice, because we're not going to be taking care of any of the very major problems in the world like COVID or like climate change, or racism or sex trafficking, or war, or all the many things that have really come forth in the last few years as super problems. Unless we have a conversation going, we're not going to be able to deal with those but the future looks pretty grim if we're not going to be able to deal with those things, it looks like pretty calamitous. And the only way we're going to get there is by really finding a way to communicate together. And that's what he's a stand for now, as he's been since the moment he arrived on Earth March 01, 1958.   As an Organization, Programmes that Can Be Put in Place to Support Team Members Where Mental Health is Concerned to Strengthen Customer Experience   Me: Thank you so much for sharing Dr. Moss. Now, mental health is a real thing, I don't think a lot of companies or even countries for that matter, really gives it the attention that it needs and dedication that it requires. Could you share with us as an organization, maybe one or two things that you can do as leadership in an organization or putting in place some form of programme to support team members where mental health is concerned in order to strengthen the customer experience?   Dr. Moss thinks if you're really up to having a healthy workforce, a healthy payroll, people who are really able to stand up for what's important in a customer experience, he thinks the number one thing to really get is that all people really want more than anything is to be heard, to be heard, and to be listened to, to actually be cared for, to be appreciated, to be acknowledged.   So, if you're going to do anything, he thinks to create an atmosphere in your company, or in your corporation or in your small groups, or even in your experience with the customers were the primary goal is to listen intently to what's being said. And not only what's being said with words, but what's being called for, how can you move the needle forward in a progressive way? What is the environment or the circumstances calling on you to present or you to be with including the possibility of saying nothing?   Can you listen for what's being called for to move that conversation forward and provide that creatively? We're all super creative, every one of us, including those of us who think we're not, that's just an old injury when you think you're not. The truth is we're all very creative and we are all listening at our own pace and our own level, and more than delivering what we think is right. And what he's saying is that more than anything, it's not a matter of speaking, it's a matter of listening to those people who are struggling to say that which is really important to them, whatever way they're doing it. So, he believes that more than anything, the secret ingredient here is definitely listening.   Me: So, we need to listen more because everybody wants to be seen, they want to be felt, they want to be heard. I think it's a process for sure.   Dr. Moss shared that when people disagree with us, we think it's okay to disregard them and dismiss them and unfriend them and never talk to them even if they are our siblings or best friends beforehand. So, these days we're cancelling people out of our worlds because they disagree with us on some certain issues and that's happened to him and it's happened to most people. He's lost friends in the last couple years and it's really quite painful. What's really here or there then is, listening is an act of occupation, it's not just what you do in between the time you talked and the time you're going to talk next, it's actually having those ears open and being super curious about what that person is saying, or what they're trying to get across in a way that really acknowledges and respects and accepts and maybe even forgives that person for being as confused as they are when they're confused. Because after all, if you haven't noticed, each and every one of us is thoroughly confused, some of us pretend like we're not and going to get it done. But each and every human on this planet is totally confused. Of course, how could you not be, there's some crap going on out there. Let's be fair about it, those of us who pretend that we're not confused, are almost more confused, they're more confused, they actually think that it's possible not to be confused.   Me: The ones who think they're not confused, they're deluding themselves.   Dr. Moss agreed, exactly. Come on. Let's be real about it.   Suggestion to Assist Ourselves When We're Feeling Out of Balance   Me: Now, Dr. Moss, if there was one thing to do immediately to assist ourselves when we're feeling out of balance. What would you suggest that one thing would be?   Dr. Moss thinks it's pause. Hold on a second, re configure yourself. Allow yourself to make a mistake, allow yourself to learn, allow yourself to regroup and get curious again, give yourself compassion, forgiveness, acceptance. He guesses you only asked for one thing, and he sees this as one thing. It's like, pause and reset. You can do that multiple times per day, if you want. Pause, reset, pause, reset, it doesn't take very much work.   Me: And I guess the average person is just going and going and going and going and it's like they don't actually take time. I think generally people feel like if they stop, and they're not doing something that their productivity will decrease. But in order for you to be more productive, you really do we need those pauses, don't you?   Dr. Moss agreed yes, you do. He knows how to run like the devil, he's a doctor. So, they trained him in medical school to be up 24 hours in emergency rooms, and in psychiatry to deal with suicide, and with homicide, and with alcoholism and drug addiction and overdoses and all those things. He knows how to run hard. But the truth is, in those moments where he can get maybe even 5 minutes, let alone 20 minutes. So, just stop and sit or stop and appreciate. No one ever told him he'd be alive forever. And no one definitely ever told him that this life was not without any misery. So, the truth is, there's massive misery, massive overwhelming misery all over the world. There are great reasons for it, it's not in your head, it's very real.   There's nothing wrong with you for being miserable in a miserable world when it's going on, for some reason, we have the capacity to recuperate or to reset ourselves because, have you noticed that some days when you're just so totally spent, like you don't have another ounce of energy left, that later in that same day you might have blissful moments, you might just realize the absolute beauty of life on the same day. That is a gift that came from us on creation and it's extraordinary that this too shall pass still works. Even in this world where calamities are just happenstance, they're just every day, there's shit going on that is just thoroughly and totally unacceptable.   App, Website or Tool that Dr. Moss Absolutely Can't Live Without in His Business   When asked about online resource that cannot live without in his business, Dr. Moss shared that he saw that question coming down the pike and he was thinking like, “Where am I right now with that particular question?” And he thinks the cheapest way would be to say something like email or messaging, but we'll go past that. He thinks that Slack is really interesting, although it has flaws. And he thinks that all of the apps, they have significant flaws. He thinks that Google Docs and Dropbox are super interesting, he has no idea what he would do without those two in particular. How would he handle life without Google and Dropbox? There's a lot of his stuff locked up in there, he doesn't even know how to find it.   But he thinks some of the more interesting, newer apps, as he learns about them, he's 64, so he's sort of on the back edge, he's not as quite as savvy as some of the 30 somethings like his son whose birthday is today (July 20th). But he thinks that some of those new apps are so extraordinary as they come off the press and the things they do. Some of these apps, they just do amazing things. But he thinks ultimately, the one he can't live without is he'd have to say, unfortunately, is through Google Suite.   Books that Have Had the Biggest Impact on Dr. Moss   When asked about books that have an impact, Dr. Moss shared that he likes spiritual books. He can't go very far without saying sort of like The Torah, The Talmud, The Mission, or the basic Old Testament Jewish texts, he loves those. He's not reading them this very moment, but the truth is, when he does, his whole life gets re-centered. So, it's hard to not pay attention to those books.   The books recently that he's really been enjoying, he's so excited about are by Alan Watts. He thinks Alan Watts is so brilliant, and just re centers all of this nonsense so easily in 10 and 15 minutes snippets. So, you can read little chapters, it's generally readable. And he just takes on this whole idea that time is just an illusion, or space is just an illusion, or that all we really have is now and he does it in a way that he finds to be so entertaining and refreshing.   Now, Think and Grow Rich by Napoleon Hill, he's sure other people have answered that question, has answered it with that book. He thinks it's a fine book and everything, he doesn't know that it's life changing book in his life. For some people, it really is. But once he gets past the Torah, then he has to get to what he's reading now. He's got so many books open in his living room. He has like 40 books that are open in his living room right now that he's like almost done with or partially through and he just keeps reading. He just pulled off “To Kill a Mockingbird,” he's like, “Oh, yeah, someday I'm going to read To Kill a Mockingbird, because I understand that that's going to really change my life.” But he's got like 23 books to read before he gets to that one. And then life goes on.   What Dr. Moss is Really Excited About Now!   When asked about something that he's excited about, Dr. Moss stated that that's a great question. He's working on both with himself and with his people and the new course that he's developed is called The True Voice Course. And it's about your voice mattering. Basically, it's an online course but it's mixed in with a mastermind, you get his two books, you get access to him, and you get access to a community of like-minded individuals who are really out to bring their true voice forward.   He's graduated over 50 people in his courses to move them from zero to podcasters. So, that's one group of people you get, but you also get people who are really interested in bringing their voice forward. The technology he's developed is comprehensive and he's super excited about rolling out that course, you can find it at www.truevoicepodcasting.com and the first 10 people who come into that course are actually going to get it at half price. And that's a significant savings. And they really just want those people to come in, take the course, let them know what works and if there's parts of it that are vague, or maybe they overlook so that they can make this course spectacular for everyone. This course is running out, starting this week and next week, so by the time that this airs, it should have a number of people that are in it. He's super excited about it because it really incorporates his books and his experience right there into a course where he can source people to find that true voice and bring it over to a world that's waiting.   When he says that there's a personal aspect to this, he's doing the same thing with his wife. He has a wife, a gorgeous, unbelievable, amazing human being who he calls his wife. And they have 3 cats, and they live in a pretty cool house and they're just kind of trying to figure out how to create a relationship every single day. And that's the same thing, using the same technology, because if you're not speaking your true voice, and no one is ever going to know you. And that's the way he is with Alexandra (his wife) as well on the way she is with him, and they bring forth art and communication and creativity like the Creative 8 asked for as well as The True Voice, as well as her own special style, which is through dance and art to really create a relationship that's never been done before. So, those are the two things and they're kind of related and these are special times to be able to have come through this life and still be banging away on things that truly do matter, like human connection.   Me: Now, for those of our listeners that would want to tap into this programme, is it that it is geared towards a particular type of person? Or is it open to anyone regardless of where they are in their life?   Dr. Moss shared that it really is open to anyone. But he thinks what they're really looking for, what they're finding are the people who have felt muted, who feel muffled, who feel fearful, who feel that their voices are not being heard, or that they're not speaking their true voice, and they're eager to do so. Maybe there's a new level of urgency given up all the world issues that we're now experiencing. And these often turn out to be mothers, this often turned out to be mothers on the other side of an empty nest perhaps, or a divorce, or maybe even just mothers who want their children to have the voices. They start realizing that up until now, they've been caring for so many people, but, “What about me? Like, what about the things that really matter to me?” It's the what about me people who are really taking this course by storm, who are like, “Yeah, I forgot how to speak my truth. I want to find my truth. I want to refine my truth. And then I want to deliver that truth.” And podcasting is one spectacular way to do that, it's not the only way, they help people find their voice and then naturally they find when to deliver it and how they're going to deliver it, even if it's just in their family, or if it's on a stage in front of 1000s of people. Either way, it's the same general criteria, they help you take a deep dive to finding that authentic self of yours, rediscovering it, refining it, and then delivering it to the world that really is ready and willing to listen to you.   Where Can We Find Dr. Moss Online   Instagram - @drfredmoss Facebook - @drfredmoss LinkedIn – Fred R. Moss, MD Email – drfred@welcometohumanity.net   Quote or Saying that During Times of Adversity Dr. Moss Uses   When asked about a quote or saying that he tends to revert to, Dr. Moss stated that there's a couple that come to mind. He used to answer this question with a Rolling Stones, “You can't always get what you want, but you get what you need.” He thinks that's a sweet quote. He thinks there's something else, there's, “This too shall pass.” That is a beautiful quote. And that we are spiritual beings living a human experience, there's something very beautiful about that too. He thinks that we are spiritual beings living a human experience can be very helpful as well, getting us centered into the here and now and getting that calamities and disasters and all those things that we hate, no one ever said that wasn't going to be part of this live. So, this idea of really listening in order to learn seems like it comes very easily from this notion that we are spiritual beings living a human experience.   Me: So, we'll have those two, the Rolling Stones, and this too shall pass. Really appreciate that. Now, thank you, again, Dr. Moss, for taking time out of your very busy day to hop on this podcast with us and share all of this awesome content on what you are doing, how you are trying to help people to have more real conversations to really get their message out there and just to be their most authentic and true self, it really was a wonderful conversation. Thank you so much.   Dr. Moss shared that it's his pleasure. And thanks for working through all the all the technological challenges, it really was a beautiful conversation, and he appreciates Yanique and really to Yanique and her listeners. This isn't a pitch for his product, he has a product, it's true. But it's not about that, these are difficult, urgent, real times. And what he really wants people to get is, if you don't speak, no one will ever hear you and if you don't speak your true voice, no one will ever know you. He has a capacity to source people to actually find that true voice and whether you use him or someone else, he's just really, really, really is interested in people who are ready to put their foot down and get that yeah, in what's left of this short life, even if it's 10, 20, 40, 60 years from now, you want to get heard, you want to be loved, you want to be appreciated. Okay, then let's start really getting with who you really are and making that happen. And whatever it takes to do that he implores the listeners and yourself to really step up because that's all that's left to do as far as he sees.   Me: Dr. Moss, so you have a gift for our listeners, please go ahead and share.   Dr. Moss shared that he has a gift, he wrote a book this year that he's really proud of and it takes a deeper dive into this whole notion of how this technology works. He knows the title of the book will surprise the audience, it's called Find Your True Voice and he's going to send the actual book to the listeners if they just sign up for the book, and you can find that at www.findyourtruevoicebook.com. And he'll send you a copy. And after that, he just want to hear what did you think of that book? Is there something there that can move you forward? Or where is it that this book or his talk is valuable? Because he's super interested in delivering talks, and having people really get that if we don't speak well….the future looks pretty grim.   And if we do speak, we can end all wars. And that's what that book is about really finding a true voice and it's simple to read, fun to read, fun to write, and he invites listeners to sign up for a free copy.   Please connect with us on Twitter @navigatingcx and also join our Private Facebook Community – Navigating the Customer Experience and listen to our FB Lives weekly with a new guest   Grab the Freebie on Our Website – TOP 10 Online Business Resources for Small Business Owners   Links   Find Your True Voice by Dr. Fred Moss Think and Grow Rich by Napoleon Hill   The ABC's of a Fantastic Customer Experience   Do you want to pivot your online customer experience and build loyalty - get a copy of “The ABC's of a Fantastic Customer Experience.”   The ABC's of a Fantastic Customer Experience provides 26 easy to follow steps and techniques that helps your business to achieve success and build brand loyalty. This Guide to Limitless, Happy and Loyal Customers will help you to strengthen your service delivery, enhance your knowledge and appreciation of the customer experience and provide tips and practical strategies that you can start implementing immediately! This book will develop your customer service skills and sharpen your attention to detail when serving others. Master your customer experience and develop those knock your socks off techniques that will lead to lifetime customers. Your customers will only want to work with your business and it will be your brand differentiator. It will lead to recruiters to seek you out by providing practical examples on how to deliver a winning customer service experience!

How does grief work? Kelly and Sarah tackle the big topic with a big guest.  Dr. Mary Frances O'Connor joins them for a conversation about grief and her new book, The Grieving Brain: The Surprising Science of How We Learn from Love and Loss. Dr. O'Connor shares her thoughtful insights and research on how grief is not a single circular series of phases, preparing for inevitable hard moments in one's life, and how grief can be a community experience. Kelly discusses how The Grieving Brain arrived at the exact right moment and Sarah fangirls out. Join us on The Unchosen Fork.Guest Host Bio:Mary-Frances O'Connor, PhD is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab, which investigates the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for Psychoneuroimmunology, she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, the New York Times, and The Washington Post. Having grown up in Montana, she now lives in Tucson, Arizona. For more information go to www.maryfrancesoconnor.com.Resources:O'Connor, M.-F. (2022). The Grieving Brain: New discoveries about love, loss, and learning. HarperOne. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). https://doi.org/10.1176/appi.books.9780890425596Follow the Unchosen Fork:FacebookInstagramDisclaimer: The contents of this podcast, including text, graphics, images, and other materials created and/or disseminated by The Unchosen Fork are for informational purposes only. The Contents are NOT intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition, before beginning a nutritional plan and/or taking nutritional supplements. Reliance on any information provided by this podcast, others content appearing on this podcast, or other visitors to the Site is solely at your own risk. None of the contents of this podcast are intended to be relied upon for medical treatment or diagnosis. The Unchosen Fork, their affiliates, nor any of the host family members assumes any liability or responsibility for damage or injury to person or property arising from any use of any product, service, information, or instruction contained on this Podcast.Support the show

Videos: 1. The great recycling LIE (what really happens to plastic) (10:44) 2. Is It Game Over? New NASA Report (5:30) 2. You won't believe what Justin Trudeau's government just did | Redacted with Clayton Morris (13:26) 3. Neil Oliver – Who pulls the strings – Pandemic Treaty, Wealth & Power? (2:00) 4. He's EXPOSING the truth in Syria and they don't like it | Redacted conversation w/ Kevork Almassian (first 10:00) 5. Russian Ruble now best performing currency in the world this year… another example of how US sanctions have failed. 6. Vanessa Beeley and Eva Bartlett are smeared by the Guardian for reporting the truth (3:07) 7. Kim Iversen: Inside The SECRET Bilderberg Meetings Between Spies, War Hawks And World Leaders (9:28) 8. New Rule: The Misinformation Age | Real Time with Bill Maher (HBO) 9. https://theduran.locals.com/post/2311112/title  10. https://www.youtube.com/watch?v=3maIN4-ZJl8    Strawberry Compound Shown to Protect Against Alzheimer's, Memory Loss Salk Institute for Biological Studies, June 16, 2022  The thought of losing your mind is a frightening one, but one in three Americans die with Alzheimer's or some other form of dementia. Regardless how frightening the possibility is, the chances of it happening to you aren't exactly slim, which means prevention should be at the forefront of your mind. A recent study from the Salk Institute for Biological Studies indicates prevention could be as simple as a natural foods diet—rich in fruits (such as strawberries) and vegetables containing something called fisetin. Fisetin is a flavonol found in strawberries, mangoes, cucumbers, and other vegetables and fruits. Researchers with the Salk Institute found this simple compound can actually reduce the risk of Alzheimer's in mice, and could be effective in humans as well. Maher and her team have documented that fisetin has both anti-inflammatory and antioxidant properties in the brain. It is also able to turn on a cellular pathway related to memory function. The team looked to a type of mouse with mutated genes making them vulnerable to Alzheimer's. At three months old, the researchers began feeding the mice a diet enriched with fisetin. Mice who hadn't received the fisetin began struggling in the mazes at nine months of age, but the fisetin mice performed as well as normal (non-predisposed) mice at both nine and twelve months of age. Avocados may hold the answer to beating leukemia University of Waterloo (Canada), June 16, 2022 Rich, creamy, nutritious and now cancer fighting. New research reveals that molecules derived from avocados could be effective in treating a form of cancer. Professor Paul Spagnuolo from the University of Waterloo has discovered a lipid in avocados that combats acute myeloid leukemia (AML) by targeting the root of the disease – leukemia stem cells. Worldwide, there are few drug treatments available to patients that target leukemia stem cells. “The stem cell is really the cell that drives the disease,” said Professor Spagnuolo, in Waterloo's School of Pharmacy. “The stem cell is largely responsible for the disease developing and it's the reason why so many patients with leukemia relapse. We've performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed.” Inability to stand on one leg for 10 seconds in mid to later life linked to near doubling in risk of death Exercise Medicine Clinic-CLINIMEX (Brazil) and University of Eastern Finland, June 21, 2022 The inability to stand on one leg for 10 seconds in mid- to later life is linked to a near doubling in the risk of death from any cause within the next 10 years, finds research published online in the British Journal of Sports Medicine This simple and safe balance test could be included in routine health checks for older adults, say the researchers. The researchers wanted to find out whether a balance test might be a reliable indicator of a person's risk of death from any cause within the next decade, and, as such, might therefore merit inclusion in routine health checks in later life. Participants were asked to stand on one leg for 10 seconds without any additional support.  To improve standardization of the test, participants were asked to place the front of the free foot on the back of the opposite lower leg, while keeping their arms by their sides and their gaze fixed straight ahead. Up to three attempts on either foot were permitted. In all, around 1 in 5 (20.5%; 348) participants failed to pass the test. The inability to do so rose in tandem with age, more or less doubling at subsequent 5 year intervals from the age of 51-55 onwards.  The proportions of those unable to stand on one leg for 10 seconds were: nearly 5% among 51-55 year-olds; 8% among 56-60 year-olds; just under 18% among 61-65 year-olds; and just under 37% among 66-70 year-olds.  More than half (around 54%) of those aged 71-75 were unable to complete the test. In other words, people in this age group were more than 11 times as likely to fail the test as those just 20 years younger. During an average monitoring period of 7 years, 123 (7%) people died: cancer (32%); cardiovascular disease (30%); respiratory disease (9%); and COVID-19 complications (7%). The proportion of deaths among those who failed the test was significantly higher: 17.5% vs. 4.5%, reflecting an absolute difference of just under 13%. Anxious Children have Bigger “Fear Centers” in the Brain Stanford University School of Medicine, June 16, 2022 The amygdala is a key “fear center” in the brain. Alterations in the development of the amygdala during childhood may have an important influence on the development of anxiety problems, reports a new study in the current issue of Biological Psychiatry.

 Researchers at the Stanford University School of Medicine recruited 76 children, 7 to 9 years of age, a period when anxiety-related traits and symptoms can first be reliably identified.  The researchers found that children with high levels of anxiety had enlarged amygdala volume and increased connectivity with other brain regions responsible for attention, emotion perception, and regulation, compared to children with low levels of anxiety. They also developed an equation that reliably predicted the children's anxiety level from the MRI measurements of amygdala volume and amygdala functional connectivity.

The most affected region was the basolateral portion of the amygdala, a subregion of the amygdala implicated in fear learning and the processing of emotion-related information.

 Our study represents an important step in characterizing altered brain systems and developing predictive biomarkers in the identification for young children at risk for anxiety disorders,” Qin said.  New research: Olive oil compound destroys cancer cells in 30 minutes Rutgers University & Hunter College, June 12, 2022  Oleocanthal, a polyphenolic, therapeutic compound found in olive oil is the subject of a new anti-cancer study performed by nutritional science and cancer biology researchers with The School of Environmental and Biological Sciences at Rutgers and Hunter's College in New York City. Programmed cell death, known as apoptosis takes approximately 16-24 hours. Dynamic new research just published in the Journal of Molecular and Cellular Oncology blew scientists away – when exposed to oleocanthal, a polyphenol compound found in olive oil, cancerous cells died within 30 minutes to an hour. While researchers previously understood that compounds in olive oil were capable of killing cancer cells, until now, such short apoptosis had not been observed. Even more fascinating was when the team looked closely to surmise why apoptosis was occurring under such swift circumstances – they discovered that cancer cells were being killed by their own enzymes. And, not only one isolated type of cancerous cell, but all of the cancerous cells they were examining. Unlike chemotherapeutic pharmaceuticals that devastate healthy cellular activity, the therapeutic polyphenolic compound found in olive oil kills cancer while maintaining vitality among healthy cells. As Paul Breslin, one of the study's authors at Rutgers noted, while cancerous cells died, healthy cells were not harmed, but rather the oleocanthal “put them to sleep.” The lifecycle of healthy cells was only temporarily affected in this way, without any negative observations and in approximately 24 hours, the healthy cells resumed their life cycle.  Sports, not screens: The key to happier, healthier children University of South Australia, June 21, 2022 Whether it's sports practice, music lessons or a casual catch up with friends, when children are involved in after-school activities, they're more likely to feel happier and healthier than their counterparts who are glued to a screen. In a new study conducted by the University of South Australia, researchers found that children's well-being is heightened when they participate in extra-curricular activities, yet lowered when they spent time on social media or playing video games. Published in BMC Pediatrics, the study analyzed data from 61,759 school students in years 4 to 9, assessing the average number of days per week children participated in after-school activities (3–6pm), and measure these against well-being factors—happiness, sadness, worry, engagement, perseverance, optimism, emotion regulation, and life satisfaction. It found that most students watched TV about four days of the school week and spent time on social media about three days of the week. Our study highlights how some out-of-school activities can boost children's well-being, while others—particularly screens—can chip away at their mental and physical health. “Screens are a massive distraction for children of all ages. And whether children are gaming, watching TV or on social media, there's something about all screens that's damaging to their well-being. Students in lower socio-economic backgrounds who frequently played sports were 15% more likely to be optimistic, 14% more likely to be happy and satisfied with their life, and 10% more likely to be able to regulate their emotions. Conversely, children who played video games and used social media almost always had lower levels of well-being: up to 9% less likely to be happy, up to 8% to be less optimism and 11% to be more likely to give up on things.

Today's episode is inspired by a historical nightmare and the subsequent decades-long experiment that shaped the way we understand childhood neglect and its effects on the developing brain. In 1989, Romanian dictator Nicolae Ceausescu was overthrown and the rest of the world discovered that over 170,000 Romanian children were being kept in impoverished institutions and orphanages.These children were raised, not by loving parents or guardians, but by the metal bars of their beds and impersonal nurses. This neglect resulted in severe, lifetime, neurological issues including altered structure, function, and connectivity among different brain regions important for integrating complex information, including cognitive, social, and emotional competencies. Curious about the decades-long project that followed these children for 21 years and documented the adverse effects of neglect on the developing brain? Come and take a listen!Please rate, review, and subscribe and if you have any questions, comments, concerns, queries, or complaints, please email me at neuroscienceamateurhour@gmail.com or DM me at NeuroscienceAmateurHour on Instagram.Citations and relevant papers below:Weir K. https://www.apa.org/monitor/2014/06/neglect. www.apa.org. Published June 2014. https://www.apa.org/monitor/2014/06/neglectGreene MF. 30 years ago, Romania deprived thousands of babies of human contact. The Atlantic. Published June 23, 2020. https://www.theatlantic.com/magazine/archive/2020/07/can-an-unloved-child-learn-to-love/612253/Publications. www.bucharestearlyinterventionproject.org. Accessed May 21, 2022. https://www.bucharestearlyinterventionproject.org/publicationsThe Science of Neglect: The Persistent Absence of Responsive Care Disrupts the Developing Brain. https://developingchild.harvard.edu/wp-content/uploads/2012/05/The-Science-of-Neglect-The-Persistent-Absence-of-Responsive-Care-Disrupts-the-Developing-Brain.pdfTeicher MH, Samson JA, Anderson CM, Ohashi K. The effects of childhood maltreatment on brain structure, function and connectivity. Nature Reviews Neuroscience. 2016;17(10):652-666. doi:10.1038/nrn.2016.111Teicher MH, Dumont NL, Ito Y, Vaituzis C, Giedd JN, Andersen SL. Childhood neglect is associated with reduced corpus callosum area. Biological Psychiatry. 2004;56(2):80-85. doi:10.1016/j.biopsych.2004.03.016FeaturedGeneticsNeurosciencePsychology·January 19, 2021. Childhood Neglect Leaves Generational Imprint. Neuroscience News. Published January 19, 2021. https://neurosciencenews.com/childhood-neglect-generational-17597/Keim B. How Childhood Neglect Stunts the Brain. Wired. Accessed June 1, 2022. https://www.wired.com/2012/09/neuroscience-of-neglect/Support the show

Dr. Mary-Frances O'Connor joins Aaron to discuss her book, The Grieving Brain: The Surprising Science of How We Learn from Love and Loss. Mary-Frances O'Connor is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss, and Social Stress (GLASS) Lab in investigating the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for Psychoneuroimmunology, she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, The New York Times, and The Washington Post. Learn more about her book, A Grieving Brain. Please visit the Ethics and Public Policy's Bioethics and American Democracy program page for more information.

If you have been impacted by grief whether it is due to the death of a loved one or ambiguous loss of family members, then, this episode is for you! Welcome to today's episode featuring my amazing guest Dr Mary Frances O'Connor. Dr Mary-Frances O'Connor is a renowned grief expert, neuroscientist, Psychologist and an PhD associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab where she investigates the effects of grief on the brain and the body. Mary Frances's work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science. Mary has also been featured in the Newsweek, the New York Times, and, The UK Guardian and The Washington Post. The Grieving Brain addresses; - Why it's so hard to understand that loved one has died and is gone forever - Why grief causes so many emotions - sadness, anger, blame, guilt and yearning - Why grieving takes so long - What happens in the brain during grief - The distinction between grief and complicated grief - Why we ruminate so much after we lose a loved one - How we ago about restoring a meaningful life while grieving. Grief is something that we're all going to experience at some point in our lives and sadly it is unavoidable. By becoming familiar of what we will actually go through, we can somehow have some mental preparation and also realise that we're not alone in how we feel. Family estrangement is categorised as an ambiguous loss which also involves the processes of grieving. Family estrangement is complicated and I believe the book discussed in this episode and the episode itself will shed some lights as why you're struggling family estrangement. To purchase - The Grieving Brain - Click on this link - https://www.amazon.co.uk/Grieving-Brain-Surprising-Science-Learn/dp/0062946234 Connect with Mary-Frances O'Connor Website: https://www.maryfrancesoconnor.com/ Linkedin: https://www.linkedin.com/in/maryfrancesoconnor/ Twitter: https://twitter.com/doctormfo Connect with Mariam https://www.instagram.com/recoveryfromfragmentedfamilies/ https://www.facebook.com/groups/587817455514932/ Book a one to one coaching; https://calendly.com/recoveryfromfragmentedfamilies/60min?month=2022-03 or book a free 15 minutes discovery call: https://calendly.com/recoveryfromfragmentedfamilies/15min?month=2022-03 Join the family estrangement support group: https://recoveryfromfragmentedfamilies.vipmembervault.com/products/courses/view/1121

In this episode I had the honor to speak with Sameer Sheth about recent advances in deep brain stimulation for psychiatric indications. We focus on two recent publications, a paper published in Biological Psychiatry that introduced a revolutionary novel concept of treating depression by inserting stereo-EEG electrodes to determine the individual circuitry involved in each patient's disease. The second was published in Nature Medicine and involved long-term local field potential recordings carried out during daily live in patients with obsessive compulsive disorder. It was a very unique opportunity to learn more about the background on how these studies originated, how they were carried out, and what the future may bring for this exciting field & I hope you enjoy the conversation I had with Sameer as much as I did.

ABOUT THE AUTHOR: Mary-Frances O'Connor, PhD is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab, which investigates the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for Psychoneuroimmunology, she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, the New York Times, and The Washington Post. Having grown up in Montana, she now lives in Tucson, Arizona. For more information go to https://www.maryfrancesoconnor.com/     Loss of a loved one is something everyone experiences, and for as long as humans have existed, we have struggled when a loved one dies. Poets and playwrights have written about the dark cloak of grief, the deep yearning, and devastating heartache of loss. But until now, we have had little scientific perspective on this universal experience.  In THE GRIEVING BRAIN: The Surprising Science of How We Learn from Love and Loss (HarperOne; February 1, 2022; Hardcover) renowned grief expert, neuroscientist, and psychologist Mary-Frances O'Connor, Ph.D., shares groundbreaking discoveries about what happens in our brain when we grieve, providing a new paradigm for understanding love, loss, and learning.   In The Grieving Brain, O'Connor, who has devoted decades to researching the effects of grief on the brain, reveals a fascinating new window into one of the hallmark experiences of being human. She makes cutting-edge neuroscience accessible and guides us through how we encode love and grief. With love, our neurons help us form attachments to others; but, with loss, our brain must come to terms with where our loved ones went, and how to imagine a future that encompasses their absence. Significantly, O'Connor debunks Kubler-Ross' enduring idea of the “Five Stages of Grief” and sets a new paradigm for understanding grief on a neurological level.  

Summary:Have you wondered why death of someone we love is so hard to believe, and then to accept? Listen in - listen for the analogy of the dining room table. (Despite saying near the beginning of the podcast that we won't reveal it, we do eventually talk about it.) With this seemingly simple explanation, it all made sense. Dr. O'Connor chats with us today about her findings related to what happens in our brain when we grieve, outlined in her recently published book, The Grieving Brain.Episode Notes:Mary-Frances O'Connor, PhD is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab, which investigates the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for Psychoneuroimmunology, she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, the New York Times, and The Washington Post. Having grown up in Montana, she now lives in Tucson, Arizona. Contact: www.asiliveandgrieve.cominfo@asiliveandgrieve.com Facebook:  As I Live and Grieve Instagram:  @asiliveandgrieve To Reach Dr. O'Connor: Website:   https://www.maryfrancesoconnor.com/ Credits: Music by Kevin MacLeod 

For episode homepage, resources and links, visit: https://kristenmanieri.com/episode168/   Description Beyond the emotional experience of loss, researchers are now discovering what happens in our brain when we grieve. In her new book, The Grieving Brain, neuroscientist and psychologist Mary-Frances O'Connor, PhD, shares a fascinating scientific perspective on the universal experience of grief, providing a new paradigm for understanding love, loss, and learning. O'Connor has devoted decades to researching the effects of grief on the brain, and makes the cutting-edge neuroscience accessible so that we can better understand what happens when we grieve and how to navigate loss with more ease and grace.   Guest Bio Mary-Frances O'Connor is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss, and Social Stress (GLASS) Lab in investigating the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for Psychoneuroimmunology, she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, New York Times, and Washington Post.   Host Bio Kristen Manieri is the author of Better Daily Mindfulness Habits: Simples Changes with Lifelong Impact (July 2021: Rockridge Press). She's certified both as a habits coach and mindfulness teacher. She specializes in: stress reduction, energy management, mindset, resilience, focus, habit formation, rest rituals, and prioritizing personal well-being. As the host of the weekly 60 Mindful Minutes podcast, an Apple top 100 social science podcast, Kristen has interviewed over 140 authors and thought-leaders about what it means to live a more conscious, connected, intentional AND joyful life. Learn more at https://kristenmanieri.com/work-with-me/.   Mentioned in this Episode   Guest's book: The Grieving Brain: The Surprising Science of How We Learn from Love and Loss: https://www.amazon.com/Grieving-Brain-Surprising-Science-Learn/dp/0062946234   Guest's website: https://www.maryfrancesoconnor.com/   Connect with the 60 Mindful Minutes podcast   Web: https://kristenmanieri.com Email: Kristen@kristenmanieri.com   Facebook: https://www.facebook.com/60MindfulMinutes Instagram: https://www.instagram.com/kristenmanieri_/ Pinterest: https://www.pinterest.com/kristenmanieri/    

Mary-Frances O'Connor, PhD is an associate professor of psychology at the University of Arizona, where she directs the Grief, Loss and Social Stress (GLASS) Lab, which investigates the effects of grief on the brain and the body. O'Connor earned a doctorate from the University of Arizona in 2004 and completed a fellowship at UCLA. Following a faculty appointment at UCLA Cousins Center for Psychoneuroimmunology, she returned to the University of Arizona in 2012. Her work has been published in the American Journal of Psychiatry, Biological Psychiatry, and Psychological Science, and featured in Newsweek, the New York Times, and The Washington Post. Having grown up in Montana, she now lives in Tucson, Arizona. For more information go to https://www.maryfrancesoconnor.com/ Sign up for 10% off of Shrink Rap Radio CE credits at the Zur Institute

In mental health treatment today, psychedelic-assisted psychotherapy is nothing less than a sensation, and some of the most promising results are in addiction treatment. Droves of people—from researchers and clinicians to underground shamans and private funders—are hailing the re-emergence of psychedelics like psilocybin, MDMA,  ayahuasca, and ketamine as a “renaissance.” But despite the hype and money being funneled in this direction, big questions remain. What do these substances actually do? How should we use them? And from a broader perspective, how are we supposed to integrate them into our existing, troubled systems?   Dr. Elias Dawkar is an addiction psychiatrist and psychiatric researcher at Columbia on the frontlines of investigating these questions. He has combined ketamine infusions with mindfulness-based relapse prevention and other addiction therapies and found some stunning rates of recovery. Despite being an accomplished scientist, though, Elias is no reductionist—a clinician and a committed meditation practitioner himself, he has a refreshingly nuanced and integrative perspective on the use of psychedelics. For him, addiction is just one manifestation of deeper efforts to free oneself from a “primordial suffering,” and he offers psychedelics in that spirit: “an opportunity for having the freedom the freedom they were looking for in the first place. The freedom, within themselves, from suffering.” In fact, he also has serious qualms about some of the ways psychedelics are being fit into medicine and the marketplace. Elias Dakwar, M.D., is an Associate Professor of Clinical Psychiatry at the Columbia University Department of Psychiatry, where he is also affiliated with the Columbia Center for Healing of Opioid and Other Substance Use Disorders (CHOSEN). After completing a fellowship in Addiction Psychiatry at Columbia, he began studying the use of ketamine infusions combined with mindfulness training to treat cocaine use disorders. He is now a principal investigator on several large grants evaluating ketamine for the treatment of opioid use disorder, cocaine use disorder, and alcohol use disorder. His work has been published in the American Journal of Psychiatry, Harvard Review of Psychiatry, Biological Psychiatry, and other major scientific journals.  In this episode:  - Elias speaking at the Horizons Conference in New York City. - The connections between psychedelics and other contemplative practices, like vipassana, Vedic mantra-based meditation, and Zen meditation, and how Elias brings mind-body practices into his clinical work. - Elias's perspective on recovery and addiction, and making sense of addiction as just one manifestation of a process of suffering. - Albert Hoffman's storied “Bicycle Day”, the first recorded LSD trip. (a cool illustration here) - The Immortality Key, a historical investigation into the role psychedelics have played in the origins of Western civilization- The pitfalls of psychedelics: at the individual level, attachment to experience and reifying the trip itself. At the social level, how overmedicalization can miss out on cultural and community renewal as part of flourishing.  Sign up for my newsletter for regular updates on new interviews, material, and other writings.

I happened to cross paths with THE LATEST buzzing study revealing how researchers have found a region of the brain stem called the periaqueductal gray which may mediate religiosity and spirituality in humans... You can find the link to the original article right down below! - Original Research: Closed access. “A Neural Circuit for Spirituality and Religiosity Derived From Patients With Brain Lesions” by Michael Ferguson et al. Biological Psychiatry

A fermented-food diet increases microbiome diversity and lowers inflammation, study finds Stanford University, July 13, 2021 A diet rich in fermented foods enhances the diversity of gut microbes and decreases molecular signs of inflammation, according to researchers at the Stanford School of Medicine.  In a clinical trial, 36 healthy adults were randomly assigned to a 10-week diet that included either fermented or high-fiber foods. The two diets resulted in different effects on the gut microbiome and the immune system. Eating foods such as yogurt, kefir, fermented cottage cheese, kimchi and other fermented vegetables, vegetable brine drinks, and kombucha tea led to an increase in overall microbial diversity, with stronger effects from larger servings. "This is a stunning finding," said Justin Sonnenburg, PhD, an associate professor of microbiology and immunology. "It provides one of the first examples of how a simple change in diet can reproducibly remodel the microbiota across a cohort of healthy adults." In addition, four types of immune cells showed less activation in the fermented-food group. The levels of 19 inflammatory proteins measured in blood samples also decreased. One of these proteins, interleukin 6, has been linked to conditions such as rheumatoid arthritis, Type 2 diabetes and chronic stress.  "Microbiota-targeted diets can change immune status, providing a promising avenue for decreasing inflammation in healthy adults," said Christopher Gardner, PhD, the Rehnborg Farquhar Professor and director of nutrition studies at the Stanford Prevention Research Center. "This finding was consistent across all participants in the study who were assigned to the higher fermented food group." Microbe diversity stable in fiber-rich diet By contrast, none of these 19 inflammatory proteins decreased in participants assigned to a high-fiber diet rich in legumes, seeds, whole grains, nuts, vegetables and fruits. On average, the diversity of their gut microbes also remained stable. "We expected high fiber to have a more universally beneficial effect and increase microbiota diversity," said Erica Sonnenburg, PhD, a senior research scientist in basic life sciences, microbiology and immunology. "The data suggest that increased fiber intake alone over a short time period is insufficient to increase microbiota diversity."  The study will be published online July 12 in Cell. Justin and Erica Sonnenburg and Christopher Gardner are co-senior authors. The lead authors are Hannah Wastyk, a PhD student in bioengineering, and former postdoctoral scholar Gabriela Fragiadakis, PhD, who is now an assistant professor of medicine at UC-San Francisco. A wide body of evidence has demonstrated that diet shapes the gut microbiome, which can affect the immune system and overall health. According to Gardner, low microbiome diversity has been linked to obesity and diabetes.  "We wanted to conduct a proof-of-concept study that could test whether microbiota-targeted food could be an avenue for combatting the overwhelming rise in chronic inflammatory diseases," Gardner said.  The researchers focused on fiber and fermented foods due to previous reports of their potential health benefits. While high-fiber diets have been associated with lower rates of mortality, the consumption of fermented foods can help with weight maintenance and may decrease the risk of diabetes, cancer and cardiovascular disease. The researchers analyzed blood and stool samples collected during a three-week pre-trial period, the 10 weeks of the diet, and a four-week period after the diet when the participants ate as they chose.  The findings paint a nuanced picture of the influence of diet on gut microbes and immune status. On one hand, those who increased their consumption of fermented foods showed similar effects on their microbiome diversity and inflammatory markers, consistent with prior research showing that short-term changes in diet can rapidly alter the gut microbiome. On the other hand, the limited change in the microbiome within the high-fiber group dovetails with the researchers' previous reports of a general resilience of the human microbiome over short time periods.  Designing a suite of dietary and microbial strategies The results also showed that greater fiber intake led to more carbohydrates in stool samples, pointing to incomplete fiber degradation by gut microbes. These findings are consistent with other research suggesting that the microbiome of people living in the industrialized world is depleted of fiber-degrading microbes.  "It is possible that a longer intervention would have allowed for the microbiota to adequately adapt to the increase in fiber consumption," Erica Sonnenburg said. "Alternatively, the deliberate introduction of fiber-consuming microbes may be required to increase the microbiota's capacity to break down the carbohydrates." In addition to exploring these possibilities, the researchers plan to conduct studies in mice to investigate the molecular mechanisms by which diets alter the microbiome and reduce inflammatory proteins. They also aim to test whether high-fiber and fermented foods synergize to influence the microbiome and immune system of humans. Another goal is to examine whether the consumption of fermented food decreases inflammation or improves other health markers in patients with immunological and metabolic diseases, and in pregnant women and older individuals.  "There are many more ways to target the microbiome with food and supplements, and we hope to continue to investigate how different diets, probiotics and prebiotics impact the microbiome and health in different groups," Justin Sonnenburg said.   Effect of resveratrol intervention on renal pathological injury in type 2 diabetes Capital Medical University (China), July 11, 2021 According to news reporting from Beijing, People's Republic of China, research stated, “Type 2 diabetes (T2D) is a clinically common cardiovascular disease that can lead to kidney damage and adversely affect male fertility and sperm quality. Resveratrol (Res) is a natural product that has a wide range of effects in animals and cell models.” The news correspondents obtained a quote from the research from Capital Medical University, “This research is designed to observe the effect of resveratrol (Res) intervention on renal pathologic injury and spermatogenesis in mice with type 2 diabetes (T2D). Sixty healthy male SD mice without specific pathogens (SPF grade) were selected, and numbered by statistical software to randomize into control group (CG; n=20), model group (MG; n=20) and research group (RG; n=20). Mice in CG were given regular diet, while those in MG and RG were fed with high fat diet. Subsequently, RG was given Res intervention while MG received no treatment. Biochemical indexes [triglyceride (TG), total cholesterol (TC), fasting blood glucose (FBG), 24-hour urinary albumin excretion rate (24h-UAER)] of mice in the three groups before and after intervention were observed and recorded. The effect of Res on oxidative stress, kidney histopathological structure, spermatogenic function, sperm density and viability of mice, as well as spermatogenic cell cycle of testis were determined. Res reduced hyperlipidemia and hyperglycemia in T2D mice. By reducing malondialdehyde (MDA) and increasing superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), Res relieved oxidative stress and alleviated kidney tissue damage. In addition, Res improved the spermatogenic function of T2D mice by increasing the sperm density and survival rate and restoring the percentage of spermatogenic cells at all levels.” According to the news reporters, the research concluded: “Res intervention in T2D mice can reduce kidney tissue damage, lower blood glucose (BG), and improve spermatogenic function by increasing sperm density and restoring the percentage of spermatogenic cells at all levels.” This research has been peer-reviewed.     Eating whole grains linked to smaller increases in waist size, blood pressure, blood sugar Study in middle- to older-aged adults suggests whole grains may protect against heart disease Tufts University, July 13, 2021 Middle- to older-aged adults who ate at least three servings of whole grains daily had smaller increases in waist size, blood pressure, and blood sugar levels over time compared to those who ate less than one-half serving per day, according to new research. Published July 13, 2021, in the Journal of Nutrition, the study by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University examined how whole- and refined-grain intake over time impacted five risk factors of heart disease: Waist size, blood pressure, blood sugar, triglyceride, and HDL ("good") cholesterol. Using data from the Framingham Heart Study Offspring Cohort, which began in the 1970s to assess long-term risk factors of heart disease, the new research examined health outcomes associated with whole- and refined-grain consumption over a median of 18 years. The 3,100 participants from the cohort were mostly white and, on average, in their mid-50s at the start of data collection. The research team compared changes in the five risk factors, over four-year intervals, across four categories of reported whole grain intake, ranging from less than a half serving per day to three or more servings per day. According to the Dietary Guidelines for Americans 2020-2025, the recommended amount of whole grains is three or more servings daily. An example of a serving is one slice of whole-grain bread, a half cup of rolled oats cereal, or a half cup of brown rice. The results showed that for each four-year interval:   Waist size increased by an average of over 1 inch in the low intake participants, versus about ½ inch in the high intake participants. Even after accounting for changes in waist size, average increases in blood sugar levels and systolic blood pressure were greater in low intake participants compared to high intake participants. The researchers also studied the five risk factors across four categories of refined-grain intake, ranging from less than two servings per day to more than four servings per day. Lower refined-grain intake led to a lower average increase in waist size and a greater mean decline in triglyceride levels for each four-year period. "Our findings suggest that eating whole-grain foods as part of a healthy diet delivers health benefits beyond just helping us lose or maintain weight as we age. In fact, these data suggest that people who eat more whole grains are better able to maintain their blood sugar and blood pressure over time. Managing these risk factors as we age may help to protect against heart disease," said Nicola McKeown, senior and corresponding author and a scientist on the Nutritional Epidemiology Team at the USDA HNRCA. "There are several reasons that whole grains may work to help people maintain waist size and reduce increases in the other risk factors. The presence of dietary fiber in whole grains can have a satiating effect, and the magnesium, potassium, and antioxidants may contribute to lowering blood pressure. Soluble fiber in particular may have a beneficial effect on post-meal blood sugar spikes," said Caleigh Sawicki. Sawicki did this work as part of her doctoral dissertation while a student at the Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University and while working with the Nutritional Epidemiology Team at the USDA HNRCA. The greatest contributor to whole-grain intake among participants was whole-wheat breads and ready-to-eat whole-grain breakfast cereals. The refined grains came mostly from pasta and white bread. The difference in health benefits between whole and refined grains may stem from the fact that whole grains are less processed than refined grains. Whole grains have a fiber-rich outer layer and an inner germ layer packed with B vitamins, antioxidants, and small amounts of healthy fats. Milling whole grains removes these nutrient-dense components, leaving only the starch-packed refined grain behind. "The average American consumes about five servings of refined grains daily, much more than is recommended, so it's important to think about ways to replace refined grains with whole grains throughout your day. For example, you might consider a bowl of whole-grain cereal instead of a white flour bagel for breakfast and replacing refined-grain snacks, entrees, and side dishes with whole-grain options. Small incremental changes in your diet to increase whole-grain intake will make a difference over time," McKeown said. Methodology To measure daily grain intake, the researchers used diet questionnaires that participants completed every four years from 1991 to 2014, resulting in a median of 18 years of data. Dietary assessment data came from five study examinations, and observations were only included if participants attended at least two consecutive examinations with accurate dietary data. Participants with diabetes at baseline were excluded. The statistical analysis was adjusted for factors that might influence the results, including other aspects of a healthy diet. Limitations of the study include the fact that food consumption is self-reported, and participants may over- or under-estimate intake of certain foods based on perceived social desirability. Due to its observational design, the study does not reflect a causal relationship.   Antibiotics in early life could affect brain development Exposure to antibiotics in utero or after birth could lead to brain disorders in later childhood Rutgers University, July 14, 2021 Antibiotic exposure early in life could alter human brain development in areas responsible for cognitive and emotional functions, according to a Rutgers researcher. The laboratory study, published in the journal iScience, suggests that penicillin changes the microbiome - the trillions of beneficial microorganisms that live in and on our bodies - as well as gene expression, which allows cells to respond to its changing environment, in key areas of the developing brain. The findings suggest reducing widespread antibiotic use or using alternatives when possible to prevent neurodevelopment problems.  Penicillin and related medicines (like ampicillin and amoxicillin) are the most widely used antibiotics in children worldwide. In the United States, the average child receives nearly three courses of antibiotics before the age of 2. Similar or greater exposure rates occur in many other countries.  "Our previous work has shown that exposing young animals to antibiotics changes their metabolism and immunity. The third important development in early life involves the brain. This study is preliminary but shows a correlation between altering the microbiome and changes in the brain that should be further explored," said lead author Martin Blaser, director of the Center for Advanced Biotechnology and Medicine at Rutgers. The study compared mice that were exposed to low-dose penicillin in utero or immediately after birth to those that were not exposed. They found that mice given penicillin experienced substantial changes in their intestinal microbiota and had altered gene expression in the frontal cortex and amygdala, two key areas in the brain responsible for the development of memory as well as fear and stress responses.  A growing body of evidence links phenomena in the intestinal tract with signaling to the brain, a field of study known as the "gut-brain-axis." If this pathway is disturbed, it can lead to permanent altering of the brain's structure and function and possibly lead to neuropsychiatric or neurodegenerative disorders in later childhood or adulthood. "Early life is a critical period for neurodevelopment," Blaser said. "In recent decades, there has been a rise in the incidence of childhood neurodevelopmental disorders, including autism spectrum disorder, attention deficit/hyperactivity disorder and learning disabilities. Although increased awareness and diagnosis are likely contributing factors, disruptions in cerebral gene expression early in development also could be responsible." Future studies are needed to determine whether antibiotics directly effect brain development or if molecules from the microbiome that travel to the brain disturb gene activity and cause cognitive deficits.  The study was conducted along with Zhan Gao at Rutgers and Blaser's former graduate student Anjelique Schulfer, as well as Angelina Volkova, Kelly Ruggles, and Stephen Ginsberg at New York University, who all played important roles in this joint Rutgers-New York University project.   Taking the brain out for a walk A recent study shows that spending time outdoors has a positive effect on our brains Max Planck Institute for Human Development, July 15, 2021 If you're regularly out in the fresh air, you're doing something good for both your brain and your well-being. This is the conclusion reached by researchers at the Max Planck Institute for Human Development and the Medical Center Hamburg-Eppendorf (UKE). The longitudinal study recently appeared in The World Journal of Biological Psychiatry. During the Corona pandemic, walks became a popular and regular pastime. A neuroscientific study suggests that this habit has a good effect not only on our general well-being but also on our brain structure. It shows that the human brain benefits from even short stays outdoors. Until now, it was assumed that environments affect us only over longer periods of time. The researchers regularly examined six healthy, middle-aged city dwellers for six months. In total, more than 280 scans were taken of their brains using magnetic resonance imaging (MRI). The focus of the study was on self-reported behavior during the last 24 hours and in particular on the hours that participants spent outdoors prior to imaging. In addition, they were asked about their fluid intake, consumption of caffeinated beverages, the amount of time spent outside, and physical activity, in order to see if these factors altered the association between time spent outside and the brain. In order to be able to include seasonal differences, the duration of sunshine in the study period was also taken into account. Brain scans show that the time spent outdoors by the participants was positively related to gray matter in the right dorsolateral-prefrontal cortex, which is the superior (dorsal) and lateral part of the frontal lobe in the cerebral cortex. This part of the cortex is involved in the planning and regulation of actions as well as what is referred to as cognitive control. In addition, many psychiatric disorders are known to be associated with a reduction in gray matter in the prefrontal area of the brain. The results persisted even when the other factors that could also explain the relationship between time spent outdoors and brain structure were kept constant. The researchers performed statistical calculations in order to examine the influence of sunshine duration, number of hours of free time, physical activity, and fluid intake on the results. The calculations revealed that time spent outdoors had a positive effect on the brain regardless of the other influencing factors. "Our results show that our brain structure and mood improve when we spend time outdoors. This most likely also affects concentration, working memory, and the psyche as a whole. We are investigating this in an ongoing study. The subjects are asked to also solve cognitively challenging tasks and wear numerous sensors that measure the amount of light they are exposed to during the day, among other environmental indicators," says Simone Kühn, head of the Lise Meitner Group for Environmental Neuroscience at the Max Planck Institute for Human Development and lead author of the study. The results therefore, support the previously assumed positive effects of walking on health and extend them by the concrete positive effects on the brain. Because most psychiatric disorders are associated with deficits in the prefrontal cortex, this is of particular importance to the field of psychiatry. "These findings provide neuroscientific support for the treatment of mental disorders. Doctors could prescribe a walk in the fresh air as part of the therapy - similar to what is customary for health cures," says Anna Mascherek, post-doctoral fellow in the Department of Psychiatry and Psychotherapy of the Medical Center Hamburg-Eppendorf (UKE) and co-author of the study. In the ongoing studies, the researchers also want to directly compare the effects of green environments vs urban spaces on the brain. In order to understand where exactly the study participants spend their time outdoors, the researchers plan to use GPS (Global Positioning System) data and include other factors that may play a role such as traffic noise and air pollution.     Vitamin C found to block growth of cancer stem cells, says peer reviewed study University of Salford (UK),  July 8, 2021   Increasingly, researchers are discovering the role played by cancer stem cells in the growth and spread of the disease. In groundbreaking new research, vitamin C showed its ability to target cancer stem cells and stop their growth – preventing the recurrence of tumors. Although mainstream medicine has been slow to accept the cancer-fighting properties of vitamin C, the exciting results of this study could help to change that. It's official: Vitamin C interferes with cancer stem cell metabolism In a newly-published study conducted at the University of Salford in Manchester, vitamin C demonstrated its power to stop tumors in their tracks by interfering with cancer stem cell metabolism – suppressing their ability to process energy for survival and growth. Cancer stem cells are responsible for triggering tumor recurrence, and promoting their growth and metastasis. Researchers believe that cancer stem cells give cancer its ability to resist chemotherapy and radiation – the reason for treatment failure in advanced cancer patients. The study, helmed by researchers Michael P. Lisanti and Gloria Bonucelli, was published last month in Oncotarget, a peer-reviewed journal. Peer-reviewed studies are considered the gold standard of scientific research. The study was the first to explore the effects of vitamin C on cancer stem cells – and provided the first evidence that vitamin C, in the form of ascorbic acid, can target and kill them. In a side-by-side comparison of seven different substances, vitamin C even outperformed an experimental cancer drug. Vitamin C works ten times better than the experimental cancer drug 2-DG The team investigated the impact on cancer stem cells of seven different substances. Three were natural substances, three were experimental drugs, and one was an FDA-approved clinical drug that is widely used. The natural products studied, along with vitamin C, were silibinin – derived from milk thistle seeds – and caffeic acid phenyl ester – or CAPE – derived from honeybee propolis. The experimental drugs were actinonin, FK866 and 2-DG, and the clinical drug was stiripentol. Researchers noted that vitamin C destroyed cancer stem cells by inducing oxidative stress. And, the vitamin performed this process ten times more effectively than 2-DG. Vitamin C used two different mechanisms of action to attack cancer stem cells. It worked as a pro-oxidant in cancer cells, depleting them of the antioxidant glutathione and causing oxidative stress and apoptosis – or cell death. It also inhibited glycolysis, which is the process that creates energy production in cell mitochondria. By inhibiting glycolysis, vitamin C inhibited mitrochondrial protein synthesis in cancer stem cells – while leaving healthy cells unaffected. Non-toxic vitamin C lacks the serious side effects of many pharmaceutical drugs Both experimental and approved cancer drugs can feature serious adverse effects, including thrombocytopenia – a deficiency of platelets in the blood that can cause bruising and slow blood clotting. They can also induce lymphopenia – a decrease in the body's infection-fighting white blood cells – and anemia, or low red blood cells. And the clinically-approved drug used in the study, stiripentol, can cause severe nausea, vomiting and fatigue. On the other hand, the National Cancer Center reports that high-dose vitamin C has caused very few side effects when used in clinical studies. Scientifically speaking, the future looks bright for vitamin C All seven of the substances tested inhibited the growth of cancer cells to varying degrees – including the non-toxic natural substances. But researchers said the most “exciting” results were with vitamin C. The research team concluded that vitamin C was a “promising new agent,” and called for more study to explore its use as an adjunct to conventional cancer therapies to prevent tumor recurrence and growth. “Vitamin C is cheap, natural, non-toxic and readily available, so to have it as a potential weapon in the fight against cancer would be a significant step,” observed Dr. Lisanti. As in most of the successful studies showing vitamin C's cancer-fighting properties, researchers used high doses of vitamin C, administered intravenously. IV vitamin C therapy is available in some alternative and holistic cancer treatment clinics worldwide. The real reason why vitamin C is ignored by conventional medicine and the mainstream media Again, vitamin C was 1,000 percent more effective than 2-DG, an experimental pharmaceutical drug – in targeting cancer stem cells. If vitamin C were developed by big pharma, these results would be shouted from the rooftops and featured in newspaper headlines. Yet, as always, “the powers that be” in mainstream medicine respond with…crickets. The reason; say natural health experts, is all too obvious. As a natural nutrient and vitamin, vitamin C can't be patented, and is inexpensive and easy to obtain. Therefore, there is no incentive for cancer clinics to promote it – when they can instead rake in the profits from chemotherapy. The indifference of conventional medicine to vitamin C is all the more frustrating because the nutrient has been shown to be an effective and non-toxic anti-cancer agent in previous studies, including many conducted by Nobel prize-winning scientist Linus Pauling. Vitamin C has been shown in a Japanese study to cut mortality in cancer patients by 25 percent. In addition, it has inhibited tumors in animal studies, and been shown to kill cancer cells in a wide variety of cancer cell lines. How much longer will the potential of this safe and powerful cancer-fighting nutrient be overlooked?     Mothers' high-fat diet affects clotting response in sons, mice study finds University of Reading (UK), July 13, 2021 Mothers who follow a high fat diet may be affecting the cardiovascular health of their sons, according to a new study in mice. In a paper published in Scientific Reports, a team of scientists found that the male children of mice mothers who were fed on a high fat diet during pregnancy had unhealthy platelets, which are responsible for clotting, when fed on a high fat diet themselves. Although both male and female children of the mothers fed on a high fat diet showed a variety of risks associated with cardiovascular disease, it was only the platelets of male mice which were considered hyperactive. These platelets were larger, more volatile and showed signs of stress compared to offspring fed on a normal diet. Dr. Dyan Sellayah, lecturer in cellular and organismal metabolism at the University of Reading said: "Heart disease is one of the UK's biggest killers and mounting evidence suggests that the risk of developing it may be increased during early development, particularly during the gestation period where mothers have a high-fat diet/are obese. The underlying mechanisms by which an unhealthy maternal diet may impact heart disease risk remains largely unknown. "This study used a mouse model of maternal obesity to understand how specialist blood cells known as platelets may be programmed during pregnancy. Platelets are important for blood clotting but are also the cause of heart attacks and strokes if they are activated at the wrong time and place." Children of the mothers fed on a high fat diet who followed a control diet however did not show the same concerning heart disease risks. The offspring from the group given a control diet had very similar levels of fat mass, cholesterol and other markets of cardiovascular health as the children of mothers fed a standard diet. In addition, where mothers had been fed a standard diet and their offspring fed a high fat diet, those children had higher levels of fat mass and other cardiovascular markers, but their platelets were statistically similar to the other groups apart from where both mum and child were fed high fat diet.  Dr. Craig Hughes, lecturer in cardiovascular biology at the University of Reading said: "This study revealed that maternal obesity during pregnancy causes offspring platelets to become hyperactive in response to a high-fat diet in adulthood. These results raise the possibility that the risk of unwanted blood clotting (aka thrombosis) in adulthood could be altered during pregnancy by diet of the mother. "The specific mechanisms for why high fat diets affect male offspring are still being investigated but we can see that there's likely to be a double-hit where both mums and sons diets together were required to see these bigger, more hyperactive platelets."

The paper we discuss is H Tyagi et al. (2019) A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects. Biological Psychiatry 85:726-734.You can find a copy of the Yale Brown Obsessive Compulsive Scale (Y-BOCS), complete with detailed instructions for administering the scale, here.A bit more information on the set-shifting/cognitive flexibility task used in the study can be found here.

Alexander is currently a postdoc as a member of the personalized medicine cluster in Copenhagen and at the Institute of Biological Psychiatry in Roskilde working with the UK Biobank and other large-scale population cohorts. Alexander has a big interest in the integration of large biomedical data in genomics, structural biology, pharmacology, and pharmacoepidemiology with innovative computational methods to gain novel insights into receptor biology. During his Ph.D. with David Gloriam at the Department of Drug Design and Pharmacology in Copenhagen, he worked on novel analytical methods to identify human signaling systems and thereby discovered endogenous peptides activating several orphan receptors. Alexander had a research sabbatical with Madan Babu at the MRC Laboratory of Molecular Biology in Cambridge, UK, where he was working on the impact of genetic variations on drug response. He received the “HC Ørsted Research talent prize” and “Bayer Pharmaceuticals Ph.D. Award” for his work on GPCRs. ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. To build our #GPCR Ecosystem, we created various enabling outlets. For more details, visit our website http://www.DrGPCR.com/Ecosystem/. Are you a #GPCR professional? - Register to become a Virtual Cafe speaker http://www.drgpcr.com/virtual-cafe/ - Subscribe to our Monthly Newsletter http://www.drgpcr.com/newsletter/ - Listen and subscribe to #DrGPCR Podcasts http://www.drgpcr.com/podcast/ - Support #DrGPCR Ecosystem with your Donation. http://www.drgpcr.com/sponsors/ - Reserve your spots for the next #DrGPCR Virtual Cafe http://www.drgpcr.com/virtual-cafe/ - Watch recorded #DRGPCR Virtual Cafe presentations: https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw - Bring in a #GPCR Consultant http://www.drgpcr.com/consulting/ - Share your feedback with us: http://www.drgpcr.com/audience-survey/ - Become a #DrGPCR Ecosystem Member http://www.drgpcr.com/membership/

1. The Differences Between Biomedical Diseases and Mental Disorders 2. The Negative Effects of Biological Psychiatry 3. The Importance of Understanding the Myths Surrounding Biological Psychiatry 4. Some Encouragement for Counselors and Pastors Important Resources Truth in Love Episode 258 here Harvard Review of Psychiatry Article here Journal of Psychological Medicine Article here Positive Results and the Hierarchy of Sciences Article here The New England Journal of Medicine Article here

1. A Brief History of Biological Psychiatry 2. The Influence of Media on Society's Understanding of Mental Health 3. How to Understand and Interpret Scientific Research and Data Important Resources Truth in Love Episode 258 here Harvard Review of Psychiatry Article here Journal of Psychological Medicine Article here Positive Results and the Hierarchy of Sciences Article here The New England Journal of Medicine Article here

本集主題：「職場冷暴力」新書介紹 專訪作者：林煜軒 博士／醫師 內容簡介： 當老闆或同事刻意疏遠、排擠你， 或貶低、批評、羞辱，惡意操弄你…… 甚至剝削、掠奪你在工作上的展現。 這些都是令人不寒而慄，卻難以啟齒的職場冷暴力。 職場冷暴力的根源──6種人格缺陷，你遇到了哪幾種？ 3種慣老闆： ‧反社會型人格老闆：「做業務的就是髒。你明年業績沒180%，不用來了！」 ‧狂妄型自戀人格老闆：「員工就是聽命的奴才，還肖想跟我平起平坐！」 ‧強迫型人格老闆：「哪個員工比我早下班，他就絕對大有問題。」 3種豬隊友同事： ‧戲劇型人格同事：你咬牙煎熬完成的工作，功勞全被收割、掠奪。 ‧依賴型人格同事：「你才剛來公司，為什麼不做以前大家都在做的事？」 ‧畏避型人格同事：遇事不斷推拖閃躲飄，你一問，他還說那是你的問題。 不是你「做得不夠好」，而是你正遭受職場冷暴力的茶毒 職場冷暴力對一個人最大的戕害，是傷人不見血。它如冰刃，日日侵蝕著你的尊嚴，再加上是在上對下的權力關係裡，因此你開始合理化對方的冷暴力，甚至自我懷疑，苛責自己做得不夠好。 慣老闆或許是職場冷暴力的始作俑者，但豬隊友同事卻常成為幫兇或共犯，如豬隊友同事揣摩上意，與慣老闆沆瀣一氣，而你淪為被孤立、霸凌的對象，日日彷若坐牢。 擁有醫療界、學術界及企業界資歷的林煜軒精神科醫師，他以豐沛的實務經驗及專業的學養，犀利又細膩地分析6種人格缺陷，從冷暴力如何巧妙地如同癌症擴散、蔓延，到身為小職員的我們，該如何調適、應對，甚至若最後選擇離職，林醫師也提供最實用的轉職處方箋。 作者簡介：林煜軒 博士／醫師 國家衛生研究院助研究員級主治醫師、台大醫院精神醫學部主治醫師、台大醫學系助理教授。 林煜軒博士為國內少數兼具臨床、企業界資歷的精神科醫師，畢業於長庚大學醫學系及陽明大學腦科學研究所博士班。 林醫師在台大醫院擔任住院醫師時，在四年住院醫師任期內，在國際期刊發表了十九篇學術論文，不但創下科內空前紀錄，也遠超過助理教授的平均學術產值，之後僅花兩年時間，即取得陽明大學腦科學博士，創下最快拿到博士學位紀錄。 曾經擔任台大醫院精神醫學部主治醫師、輝瑞藥廠產品醫師（醫藥學術顧問）、台大醫院精神醫學部住院醫師及總醫師。 譯作《網路成癮──評估及治療指引手冊》獲國健署「優良健康讀物推介獎」，編製的「智慧型手機成癮量表」，目前已翻譯為德、法、西班牙、義大利、匈牙利、芬蘭、葡萄牙、土耳其、印度等多國語言。 研發三款雲端服務的手機程式（App），且取得多項國內外專利。編寫國際知名網路成癮教科書中「智慧型手機成癮」章節。目前已發表三十餘篇學術論文於國際期刊。 曾獲台灣生物精神醫學會「保羅楊森博士研究論文獎」（二○一八年、二○一六年、二○一三年）、第十一屆世界生物精神醫學會（World Congress of Biological Psychiatry）：「最佳學術海報」、「青年學者旅行獎（Travel Award）」（日本京都，二○一三年）、財團法人台灣醫學發展基金會論文獎「優等獎」（二○○七年）、台灣睡眠醫學會大會論文獎「口頭論文優選獎」（二○○七年）。 平日熱愛古典音樂與棋藝，曾任長庚大學弦樂團小提琴首席，且為中華民國圍棋協會六段棋士。

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

REPORT PRESENTED DURING THE WORKS OF THE 12TH CONGRESS OF THE SIPB - Italian Society of Biological Psychiatry held in Naples (2 - 5 October 2019)

What happens when you combine the volatility of the internet with an off-hand comment designed to stop drug addicts from flushing their evidence. The answer? Meth-gators. What on Earth is a Meth-gator? Is this a true phenomenon or the internet running wild? More importantly, why is it worth talking about here? Join hosts Shanti and Danny as they talk about meth, gators, the police, and some weird testing on monkeys on this light-hearted episode of Breaking Bad Science. ReferencesRosenblatt, K.; Meth-gators: Tennessee Police Warn Flushing Drugs Could Create Hyper-Aggressive Alligators. NBC News. 16-Jul-2019. https://www.nbcnews.com/news/us-news/tennessee-police-warn-locals-not-flush-drugs-fear-meth-gators-n1030291Diochot, S. et. al.; Black Mamba Venom Peptides Target Acid-Sensing Ion Channels to Abolish Pain. Nature. 03-Oct-2012. 490 (552 - 555). Doi: https://doi.org/10.1038/nature11494BBC News; Drug-Addicted Python Rehabilitated by Australian Prisoners. BBC News Australia. 12-Apr-2017. https://www.bbc.com/news/world-australia-39550815Pei, Z., Zhang, X.; Methamphetamine Intoxication in a Dog: Case Report. BioMed Central Veterinary Research. 24-Jun2014. 10:139. Doi: 10.1186/1746-6148-10-139Tierney, A.; The Evolution of Learned and Innate Behavior: Contributions from Genetics and Neurobiology to a Theory of Behavioral Evolution. Animal Learning and Behavior. Dec-1986. 14: (339 - 348). Golden, S., et. al.; Compulsive Addition-Like Aggressive Behavior in Mice. Biological Psychiatry. 15-Aug-2017. 82: 4 (239 - 248). Doi: https://doi.org/10.1016/j.biopsych.2017.03.004

EAZYSENSE is helping people through the Pandemic-Help to support our work!Breaking news and more breaking news Cheers to the Broderick lab-Why? The photo shoot was fabulous!!! Let me tell you about it! Big news is that we are set with India and that means Japan and Spain are not far beyond.Big news is that we reopened our lab today under Covid guidelines and our dean for research Dr. Maria Lima is great. My CFO Paul Sethi is with us and will be with us on the radio soon. Paul is on..he is on the money and I am happy!!Now brainwork @ eazysense.com is all set up- All support is going to Easysense Nanotechnologies. the actual bank account to take care of support. photo-diodes and lasers and Rachel Silva is with us to tell us what Crowdfunding is and now I am working with Wuhan!!!!!!!Member of the Board-Psyche for Biological Psychiatry, Dr. Tom Schlapfer. Biological Psychiatry.every day-every day I started with honors from Dr. Nathan Kline. From sad to glad. the biological cowboy!!!!!!! antidepressants do work but covid is causing depression and suicide.Ironic! We have now built 240 Miles of new Border Wall on our Southern Border. We will have over 450 Miles of the year. here-remember Border was closed by Mexico to us due to covid and Canada on the other end has closed its border Daily Comment The Essential and Enduring Strength of John Lewis By Jelani Cobb July 19, 2020John LewisThe news of John Lewis's death prompts a question: What does one do when a figure of his stature departs? Photograph by David Deal / Redux By the time John Lewis made his exit from this realm, on Friday, his life had been bound so tightly and for so long to the mythos of the movement for democracy in America that it was difficult to separate him from it. For this reason, a friend who texted me "John Lewis is gone, what are we going to do now?" was not only reacting to grief but expressing a real and common sentiment. Lewis, who spoke at the March on Washington, chaired the Student Non-Violent Coordinating Committee, and served seventeen terms in Congress, representing Georgia's Fifth District, succumbed to pancreatic cancer, a ruthless and efficient plague whose diagnosis is fatal around ninety-five per cent of the time. When he revealed his condition, last December, hope persisted despite those odds, in part because, for many people, the thought of confronting the reactionary, racist, and antidemocratic realities of the Trump era without one of the nation's most potent symbols of decency was too difficult to countenance.LET'S GO TO SELMAin Selma, 1963 Alabama, that were part of the campaign for a national voting-rights act. He wrote of the moment in his memoir "Walking with the Wind," from 1998: The first of the troopers came over me, a large, husky man. Without a word, he swung his club against the left side of my head. I didn't feel any pain, just the thud of the blow and my legs giving way. I raised an arm—a reflex motion—as I curled up in the "prayer for protection" position. And then the same trooper hit me again. And everything started to spin. Lewis, who was bleeding badly, somehow made it back across the bridge. He returned to the church that had been a staging area for the march and gave a speech denouncing Lyndon B. Johnson's priorities. "I don't know how President Johnson can send troops to Vietnam, I don't see how he can send troops to the Congo, I don't see how he can send troops to Africa, and can't send troops to Selma" he said. The footage of brutal bedlam in Selma pressured Johnson to support what eventually became the Voting Rights Act of 1965. From the New Yorker! COVID AND THE NEW ARCHITECTURE!Unlike the airy, pristine emptiness of modernism, the space needed for quarantine is primarily defensive, with taped lines and plexiglass walls segmenting the outside world into zones of socially distanced safety. Wide-open spaces are best avoided. Barriers are our friends. Stores and offices will have to be reformatted in order to reopen, our spatial routines fundamentally changed. And, at home, we might find ourselves longing for a few more walls and dark corners.We need to talk about 5 G People are protesting! Are these small cells or big ugly and expensive towers. Support Eazysense as it will bring medicines but 5 G will ruin your daily life. Is this too strong?Schumamn's resonance-stumped people with this but getting the word out. How about cell phones we have now-we need to get to this discussion.I am an expert on proteins!!!!! Now all this about Hertz---and devastating towers am I saying just that the towers are not pretty and you will not have your bagels toasted correctly. But that is not what the only thing that I am saying!!!!!__?????????

This evening, Dr. Broderick will talk about: EAZYSENSE is helping people through the Pandemic-Help to support our work!Breaking news and more breaking newsOTThe Covid, The 5G Brain Mixed! Blake/Justin are back!!!!Cheers to the Broderick lab-Why?......writing a new 2020 patent and it ain't easy!:) AND IT IS GREAT!Jim and Lisa were great last week-we are bringing them back!Now brainwork @ eazysense.com is all set up- I was with people in the know. All support is going to Easysense Nanotechnologies. the actual band account to take care of support. From here, we have worked overseas to set up our work with India, Japan and Spain. The contract with India is signed and approved by the Indian Government and it resides in the Indian Government is my name..All is happily disclosed to the University for Reopening of Laboratories. Therefore, Please support us with any amount of support and the funds will be shared with the Broderick Brain Foundation. I do know who contributes and a gift will be given to those who share large amounts and a letter to prove it is a legal donation for a 501 c3 will be provided. It is called crowd funding!!! zelle is the best and the most secure as this is set up in my Easysense Nanotechnologies Acct.It cannot get mixed up!! and 2 photo shoots tomorrow!!!!!! Hectic and wonderful despite COVID 19.Wow!! alot of coordination and setting up but we are getting there. It is on the 16th!!! Top 100 Registry! Top Innovator and Global Woman of the Year. in my home and garden--i have to admit I am excited.Clark Edwards listened. to the show. We have many new listeners, Calgary Canada is listening. Bill Tong- -my sister Josephine and Dr. Gill do share the suffering of quadriplegia Now we can do something. Advisory Board-BT-Neuro-Medware and now Member of the Board-Psyche for Biological Psychiatry, Dr. Tom Scnlapfer. Biological Psychiatry.every day-every day I started with honors from Dr. Nathan Kline. From sad to glad. the biological cowboy!!!!!!! antidepressants do work but covid is causing depression and suicide.Scholarship is due next week. The Broderick Lab is ready.

Our inaugural episode of the Carver Cast features Dr. Nii Addy, associate professor psychiatry and of cellular and molecular physiology at the Yale School of Medicine. Dr. Addy received his B.S. in Biology from Duke University and his Ph.D. in Neuroscience from Yale University. At Yale, Dr. Addy directs a federally funded research program, where he and his staff use rodent models to investigate the neurobiological bases of substance abuse, depression and anxiety. Dr. Addy is also involved in graduate student and post-graduate training, faculty mentoring, and university-wide diversity and inclusion initiatives at Yale. He serves on the journal editorial board of Biological Psychiatry, Nicotine & Tobacco Research, and Neuropharmacology, and serves as a grant reviewer for the National Institutes of Health’s Center for Scientific Review (CSR). He has presented scientific lectures at universities throughout the United States and Europe, and in Japan. Dr. Addy has also participated in Veritas Forums and community forums on the intersection of mental health, faith, culture and neuroscience. His research and community work have been featured by National Public Radio (NPR), Newsday, the National Football League Players Association (NFLPA), The Source Magazine, Chuck Norris, BoldTV, Legitimate Matters, and Relevant Magazine. -- The Carver Cast engages with Christian faculty in higher education and highlights the work of those faculty to bridge connections between university, church, and society. In doing so, it seeks to disrupt simultaneously perceptions that Christians are “anti-intellectual” and that higher education is “anti-Christian.” Tune in for a wide-ranging discussion with faculty around the country, with mediocre production quality but excellent content! Penina Laker and John Inazu are Carver Project faculty fellows and members of the faculty at Washington University in St. Louis, where Laker is assistant professor of communication design and Inazu is a professor of law and religion.

Featuring: - Mental health concerns during the Pandemic - What is the problem with adopting a DSM diagnosis for depression and anxiety - Therapy as a Replacement of Theology - Medicalizing anxiety and depression - Critically considering the efficacy of current psychiatric drugs and frameworks - What is the goal of mental health? - What is healthy? What is normal? Notes: Mental Health Month Podcast Series: - The Bible of Psychiatry - https://biblicalcounseling.com/the-bible-of-psychiatry - Biological Psychiatry - https://biblicalcounseling.com/biological-psychiatry - The Problem with the Mental Illness Narrative - Bibliography of Critical Psychology https://acbcdigitalresources.s3-us-west-2.amazonaws.com/resources/Truth+in+Love+Resources/TIL+Show+Note%3A+Featured+Resource/Critical+Psychology+Flyer_2019.pdf Send your Truth in Love Questions to info@biblicalcounseling.com

Featuring: - Mental health concerns during the Pandemic - What is the problem with adopting a DSM diagnosis for depression and anxiety - Therapy as a Replacement of Theology - Medicalizing anxiety and depression - Critically considering the efficacy of current psychiatric drugs and frameworks - What is the goal of mental health? - What is healthy? What is normal? Notes: Mental Health Month Podcast Series: - The Bible of Psychiatry - https://biblicalcounseling.com/the-bible-of-psychiatry - Biological Psychiatry - https://biblicalcounseling.com/biological-psychiatry - The Problem with the Mental Illness Narrative - Bibliography of Critical Psychology https://acbcdigitalresources.s3-us-west-2.amazonaws.com/resources/Truth+in+Love+Resources/TIL+Show+Note%3A+Featured+Resource/Critical+Psychology+Flyer_2019.pdf Send your Truth in Love Questions to info@biblicalcounseling.com

Featuring: 1. The history of Biological Psychiatry 2. Why biological psychiatry isn't a hard science 3. Do Biblical Counselors neglect biology? 4. A call for biblical discernment of popular data. 5. A critique of a popular biological psychiatry theory Notes: Bibliography of Critical Psychology https://acbcdigitalresources.s3-us-west-2.amazonaws.com/resources/Truth+in+Love+Resources/TIL+Show+Note%3A+Featured+Resource/Critical+Psychology+Flyer_2019.pdf The Sufficiency & Authority of Scripture to Diagnose & Cure the Soul https://biblicalcounseling.com/the-sufficiency-authority-of-scripture-to-diagnose-and-cure-the-soul/ Erasing the Stigma of Mental Illness – The Church's Role https://biblicalcounseling.com/erasing-the-stigma-of-mental-illness-the-churchs-role/ Biological Psychiatry by David Powlison https://www.ccef.org/shop/product/jbc-volume-17-3-pdf/

Featuring: 1. The history of Biological Psychiatry 2. Why biological psychiatry isn't a hard science 3. Do Biblical Counselors neglect biology? 4. A call for biblical discernment of popular data. 5. A critique of a popular biological psychiatry theory Notes: Bibliography of Critical Psychology https://acbcdigitalresources.s3-us-west-2.amazonaws.com/resources/Truth+in+Love+Resources/TIL+Show+Note%3A+Featured+Resource/Critical+Psychology+Flyer_2019.pdf The Sufficiency & Authority of Scripture to Diagnose & Cure the Soul https://biblicalcounseling.com/the-sufficiency-authority-of-scripture-to-diagnose-and-cure-the-soul/ Erasing the Stigma of Mental Illness – The Church's Role https://biblicalcounseling.com/erasing-the-stigma-of-mental-illness-the-churchs-role/ Biological Psychiatry by David Powlison https://www.ccef.org/shop/product/jbc-volume-17-3-pdf/

tw: OCD, checking behaviours Always portrayed with excessive hand washing or immaculate tidiness - this week we are talking all things Obsessive Compulsive Disorder or (OCD)We delve into what exactly OCD is, how it develops, discuss the thought-action fusion and  explore common treatment strategies. We also answer a listener question on how OCD is related to eating disorders.we hope you enjoy! Study: Luke Norman, Stephan Taylor, Yanni Liu, Joaquim Radua, James Abelson, Mike Angstadt, Yann Chye, Stella de Wit, Joseph Himle, Chaim Huyser, Isik Karahanoglu, Tracy Luks, Dara Manoach, Carol Mathews, Katya Rubia, Chao Suo, Odile van den Heuvel, Murat Yücel, Kate Fitzgerald. S20. Error-Processing in OCD: A Meta-Analysis of fMRI Studies and Investigation of Changes Following CBT. Biological Psychiatry, 2018; 83 (9): S354 DOI: 10.1016/j.biopsych.2018.02.911Article to access study: https://www.sciencedaily.com/releases/2018/11/181129084703.htmIf you want to see more, please follow us on our instagram @thepsychologysistersPlease note, the content shared in this episode is not personalised and should be not be used in replacement of personalised psychological advice. 

Medical notes this week… Cystic fibrosis affects about 30,000 people in the United States, prompting a severe buildup of mucus in the lungs and other organs. The major gene defect causing 90 percent of cases of CF was discovered 20 years ago, and now there's finally a three-drug combination that effectively targets it. The drug, Trikafta, is being hailed as a breakthrough and could increase the current 44-year life expectancy of people with CF. When doctors prescribe antibiotics, you're supposed to take the entire prescription, even if you feel better before then. But the National Poll on Healthy Aging shows that 13 percent of people over age 50 have pills left over from their last prescription. Most of the time, they say they're saving them for later use or for a family member. Half of those people admit they've taken leftover antibiotics without checking with a doctor first. Post-traumatic stress disorder can have effects in a lot of seemingly unrelated areas. a study in the journal Epidemiology shows that having PTSD nearly doubles a person's risk of infections. The risk increase varies by disease -1.7 times higher for the flu and more than two and a half times higher for viral hepatitis. Researchers say PTSD also seems to affect the infection risk differently for men and women. Men are more likely to get skin infections, while women are more likely to get urinary tract infections. And finally, researchers have long observed that heavy alcohol use is associated with reduced brain size, with the conclusion that alcohol can shrink the brain. But now a study in the journal Biological Psychiatry suggests that smaller brain size comes first. People with less grey matter in the brain are genetically predisposed toward alcohol consumption, which may, in turn, shrink the brain still further.

------------------Support the channel------------ Patreon: https://www.patreon.com/thedissenter SubscribeStar: https://www.subscribestar.com/the-dissenter PayPal: paypal.me/thedissenter PayPal Subscription 1 Dollar: https://tinyurl.com/yb3acuuy PayPal Subscription 3 Dollars: https://tinyurl.com/ybn6bg9l PayPal Subscription 5 Dollars: https://tinyurl.com/ycmr9gpz PayPal Subscription 10 Dollars: https://tinyurl.com/y9r3fc9m PayPal Subscription 20 Dollars: https://tinyurl.com/y95uvkao ------------------Follow me on--------------------- Facebook: https://www.facebook.com/thedissenteryt/ Twitter: https://twitter.com/TheDissenterYT Anchor (podcast): https://anchor.fm/thedissenter Dr. Ruth Feldman is the Simms-Mann Professor of Developmental Social Neuroscience at the Interdisciplinary Center (IDC) Herzlia with joint appointment at Yale Child Study Center. With degrees in music composition (summa cum-laude), neuroscience (with honors), clinical psychology (with honors), and developmental psychology and psychopathology, her approach integrates perspectives from neuroscience, human development, philosophy, clinical practice, and the arts within an interpersonal frame and a behavior-based approach. Her conceptual model on biobehavioral synchrony systematically describes how a lived experience within close relationships builds brains, creates relationships, confers resilience, and promotes creativity. Her studies were the first to detail the role of oxytocin in the formation of human social bonds. Her studies often follow children from infancy to adulthood, address topics that are highly relevant to the general public, and receive substantial media attention. Dr. Feldman is a fellow of the Association for Psychological Science and received multiple awards, including a Rothschild award, NARSAD independent investigator award (twice), the Zeskind award for best paper in Biological Psychiatry, and the Graven's Award for research on high-risk infants. In this episode, we focus on the neurobiology of attachment. We talk about the evolution of attachment, the oxytocin system, and parental investment; biobehavioral synchrony between parent and offspring; how events like postpartum depression, premature birth, and early trauma can disrupt development; and individual and sex differences in predisposition for resilience. -- Follow Dr. Feldman's work: Faculty page: http://bit.ly/33C4rXV Center for Developmental Social Neuroscience: http://bit.ly/2MoaWYL Publications: http://bit.ly/2MljmA6 -- A HUGE THANK YOU TO MY PATRONS: KARIN LIETZCKE, ANN BLANCHETTE, SCIMED, PER HELGE HAAKSTD LARSEN, LAU GUERREIRO, RUI BELEZA, ANTÓNIO CUNHA, CHANTEL GELINAS, JERRY MULLER, FRANCIS FORDE, HANS FREDRIK SUNDE, BRIAN RIVERA, ADRIANO ANDRADE, YEVHEN BODRENKO, SERGIU CODREANU, ADAM BJERRE, ŁUKASZ STAFINIAK, AIRES ALMEIDA, BERNARDO SEIXAS, HERBERT GINTIS, RUTGER VOS, RICARDO VLADIMIRO, BO WINEGARD, JOHN CONNORS, ADAM KESSEL, AND VEGA GIDEY! A SPECIAL THANKS TO MY PRODUCERS, YZAR WEHBE, ROSEY, AND JIM FRANK!

In this episode, we visit the psychiatric centre, Sankt Hans in Roskilde, to speak with Professor of Biological Psychiatry, Thomas Werge about the comprehensive research initiative, iPsych that he and five other Principal Investigators lead, - about how mental disorders can be understood better and treated diversely for different groups and individuals in the future, - and about what normal is. The Danish National Biobank is a treasury of science for international health research. It contains 10 million biosamples across an array of diagnostic categories, as well as the Danish Biobank Register that links over 25 million biosamples in Danish biobanks to vast amounts of register information. This podcast will give an insight into some of the amazing research done through the Danish National Biobank and hopefully inspire researchers to utilize this potential in the future.

In this episode we discuss the rapid rise of shamanism in the West. As shamanism becomes more popular in modern Western culture, its true characteristics are being obscured to make it more palatable to the West. We expose the well-documented dark aspects of shamanic practice and the link between shamanism and the use of psychedelic drugs. Bibliography Books Castaneda, C. (1968/1998). The Teachings of Don Juan: A Yaqui Way of Knowledge (40th Anniversity Edition). Washington Square Press. Castaneda, C. (1971/1991). A Separate Reality: Further Conversations with Don Juan (Washington Square Press) Castaneda, C. (1972/1991). Journey to Ixtlan: Lessons of Don Juan (Washington Square Press) Castaneda, C. (1993/2003). The Art of Dreaming (William Morrow) Eliade, M. (1964/2004). Shamanism: Archaic Techniques of Ecstasy. Princeton University Press. Grof, S., & Grof, C. (2010). Holotropic Breathwork: A New Approach to Self-Exploration and Therapy. State University of New York Press. Harner, M. (1990). The Way of the Shaman. Harper Collins Publishers. Harner, M. ed. (1973). Hallucinogens and Shamanism. Oxford University Press. Journal Articles Bogenschutz, M. P., & Johnson, M. W. (2016). Classic hallucinogens in the treatment of addictions. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 64, 250-258. Courchene, A. (2019). Reframing reconciliation: A move towards conciliation in academia. Academic Matters. Spring, 2019, p. 21-24. News Articles Globalnews.ca | “Health Canada allows more religious groups to import ayahuasca” (May 8, 2019) Globalnews.ca | “These Ontario police officers are using ayahuasca to treat their PTSD” (May 24, 2019) Hollywood Reporter | "How Healers Became the New Gurus of Hollywood" RollingStone | Michael Pollan: Can Psychedelics Save the World? L'Officiel | A Conversation with Gwyneth Paltrow's Spiritual Advisor, Shaman Durek Web rewildingforwomen.com/about YouTube | Michael Harner: The Way of the Shaman YouTube | Mircea Eliade pronunciation. YouTube | Mystic Tribe | What Is A Shaman? w/ Shaman Durek YouTube | All About Shamanism - Terence McKenna YouTube | Terence McKenna - The Magical Dimension Is Real YouTube | Joe Rogan and Derren Brown: Shamanism and the Psychedelic Revolutionn YouTube | Myths, Shamans and Seers: Phil Borges at TEDxRainier TEDGlobal 2014 | Mark Plotkin | "What the people of the Amazon know that you don't" YouTube | ITV News | Michael Pollan: Magic mushrooms and LSD could help solve mental health crisis YouTube | Timothy Alberino on Amazonian Shamanism YouTube | Excited delirium or something else? - Man ingests large quality of hallucinogenic mushrooms WHERE TO FIND US Website: notconformed.show notconformedshow.ca Email: info@notconformedshow.ca RSS Feed: (NEW! SimpleCast 2.0) https://feeds.simplecast.com/Q7v05iI6

Recently, there has been a renewed interest in the potential benefits of psychedelic drugs. In this episode we explore 1) how the use of psychedelic drugs can have a transformative and lasting impact on the worldviews of those who use them, 2) how a psychedelic experience can drive people to practice certain mainstream religions, and 3) claims that some mainstream religions were inspired by ancestral use of psychedelic drugs. While some people propose that psychedelics are a panacea for modern mental health issues and that they offer an easy and direct path to transcendence, we explore the dark side of the psychedelic experience, with a particular focus on the otherworldly entities people meet while under the influence of DMT (ayahuasca). Bibliography: Books: Hofmann, A. (2013). LSD my problem child. Huxley, A. (1954). The doors of perception. Kripal, Jeffrey J. (2011). Mutants & Mystics: Science Fiction, Superhero Comics, and the Paranormal. Pollan, M. (2018) How to change your mind: What the new science of psychedelics teaches us about consciousness, dying, addiction, depression and transcendence. Strassman, R. (2001). DMT: The spirit molecule. Strassman, R. (2014). DMT and the soul of prophecy Journal Articles: Bogenschutz, M.P., & Johnson, M.W. (2016). Classic hallucinogens in the treatment of addictions. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 64, 250-258. Carod-Artal, F.J. (2015). Hallucinogenic drugs in pre-Columbian Mesoamerican cultures. Neurologia, 30(1), 42-49. Dean, J. G. (2018). Indolethylamine-N-methyltransferase Polymorphisms: Genetic and Biochemical Approaches for Study of Endogenous N, N,-dimethyltryptamine. Frontiers in neuroscience, 12. Nichols, D.E. (2004). Hallucinogens. Pharmacology & Therapeutics, 101, 131-181. Magazine and News Articles: Dune, C. (2018). Welcome to the trip of your life: The rise of underground LSD guides. The Guardian. Wasson, R. G. (1957). Seeking the magic mushroom. Life, 42(19), 100-120. Clip Sources: YouTube: Joe Rogan Experience #1255 - Alex Jones Returns! YouTube: Joe Rogan Experience #1121 - Michael Pollan YouTube: ITV News - Michael Pollan: Magic mushrooms and LSD could help solve mental health crisis YouTube: DMT: A Religious Model with Rick Strassman M.D. YouTube: Rick Strassman: Test subjects' reactions to DMT YouTube: Rick Strassman - The Nature of the DMT Beings: Breaking Convention lecture July 2015 YouTube: Graham Hancock - The War on Consciousness BANNED TED TALK YouTube: Jordan Peterson on Psilocybin, MDMA, DMT as miracle cures Mentioned: CBC: Trudeau government gag order in CIA brainwashing case silences victims, lawyer says Babylon Bee Satire: Hillary Clinton Releases DNA Test Results Proving She's Only Half Lizard Person StudyFinds: Psychedelic Found In Toad Venom Helps Relieve Depression, Anxiety BBC: The LSD cult that transformed America Unseen Realm - Dr. Michael S. Heiser drmsh.com WHERE TO FIND US Website: notconformedshow.com Email: info@notconformedshow.com NEW! RSS Feed: https://feeds.simplecast.com/Q7v05iI6

In this in service Dr. Stephen Price and I discuss the relationship between mental illness and violence and delve into our experiences with this population. According to the Department of Justice violent crime has been decreasing since the early 1990s. Although there is a statistical relationship between mental illness and violence, only 4% of all violent crimes are committed by persons with mental illness. Conversely, persons with mental illness are at high risk for violent victimization. Despite this violent crimes involving persons with mental illness are over-reported. Research indicates that mental illness only needs to be mentioned in news stories for people to infer that there is a causal relationship between the two. References for this in service are listed below.   If you enjoy our podcast please consider liking us in Apple podcast. You can also find our podcast in Google, Spotify, and at https://forensicinservice.com   The music for our podcast was composed and performed by Adam Price. The artwork "Blocked Thoughts" was hand painted by Jenn Koonz, Ph.D. Both are used with permission. Forensic InService podcast by Stephen Koonz & Stephen Price is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.   References: Alia-Klein, N, O’Rourke, TM, et al. (2007). Insight into illness and adherence to psychotropic medications are separately associated with violence severity in a forensic sample. Aggressive Behavior, 33(1), 86-96. Chan, G, & Yanos, PT. (2018). Media depictions and the priming of mental illness stigma. Stigma and Health, 3(3), 253-264. Choe, JY, Teplin, LA, & Abram, KM. (2008). Perpetration of violence, violent victimization, and severe mental illness: Balancing public health outcomes. Psychiatr Serv, 59, 153-164. da Cunha-Bang, S, Hjordt LV, et al. (2017). Serotonin 1B receptor binding is associated with trait anger and level of psychopathy in violent offenders. Biological Psychiatry, 82(4), 267-274. George, DT, Umhau, JC, et al. (2001). Serotonin, testosterone and alcohol in the etiology of domestic violence. Psychiatry Research, 104(1), 27-37. Hein, S, Barbot, B, et al. (2017). Violent offending among juveniles: A 7-year longitudinal study of recidivism, desistance, and associations with mental health. Law and Human Behavior, 41(3), 273-283. Hodgins, S. (2008). Violent behavior amongst people with schizophrenia: A framework for investigation of causes and effective treatment, and prevention. Philos Trans R Soc Lond B Biol Sci, 363, 2505-2518. inSocialWork Podcast #135 - Chris Veeh: Traumatic Brain Injury and Incarcerated Youths: A Role for Social Work. (2014). Retrieved 23 September 2018, from http://www.insocialwork.org/episode.asp?ep=135. Kuehn, BM. (2012). Evidence suggests complex links between violence and schizophrenia. Journal of the American Medical Association, 308(7), 658-659. Latalova, K, Kamaradova, D, & Prasko J. (2014). Violent victimization of adult patients with severe mental illness: A systematic review. Neuropsychiatr Dis Treat, 10, 1925-1939. Lee, AMR, & Galynker, II, (2010). Violence in bipolar disorder. Psychiatric Times. Retrieved 23 Septemer 2018 from: http://go.galegroup.com/ps/anonymous?id=GALE%7CA392573273&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=08932905&p=AONE&sw=w Maio HA. (2004). Stigma and public education about mental illness: Comment. Psychiatric Services, 55(7), pp. 834. Newman, JM, Turnbull, A, Berman, BA, et al. (2010). Impact of traumatic and viiolent victimization experiences in individuals with schizoprenia and schizoaffective disorder. J. Nerv Ment Dis, 198, 708-714. Robbins, PC, Monahan, J, & Silver, E. (2003). Mental disorder, violence, and gender. Law and Human Behavior, 27(6), 561-571. Sirotich, F. (2008). Correlates of crime and violence among persons with mental disorder: An evidence-based review. Brief Treatment and Crisis Intervention, 8(2), 171-194. Swanson, JW, Holzer, CE III., Ganju, VK, et al. (1990). Violence and psychiatric disorder in the community: Evidence from epidemiologic catchment area surveys. Hops Community Psychiatry, 41, 761-770. The Lobotomist | American Experience | PBS. (2018). Pbs.org. Retrieved 28 September 2018, from https://www.pbs.org/wgbh/americanexperience/films/lobotomist/ Varney, KH. (2014). By the numbers: Mental illness behind bars. PBS News Hour. Retrieved 21 September 2018, from https://www.pbs.org/newshour/health/mental-illness-behind-bars. Varshney, M, Mahapatra, A, Krishnan, V, Gupta, R, & Debs, KS. (2015). Violence and mental illness: What is the true story? Journal of Epidemiology and Community Health, 70(3), 223-225. Weierstall, R, Moran, J, Giebel, G, & Elbert, T. (2014). Testosterone reactivity and identification with perpetrator or a victim in a story are associated with attraction to violence-related cues. International Journal of Law and Psychiatry, 37(3), 304-312.

In 1897, shortly after Zona Shue was found dead in her West Virginia home, her mother went to the county prosecutor with a bizarre story. She said that her daughter had been murdered -- and that her ghost had revealed the killer's identity. In this week's episode of the Futility Closet podcast we'll tell the story of the Greenbrier Ghost, one of the strangest courtroom dramas of the 19th century. We'll also consider whether cats are controlling us and puzzle over a delightful oblivion. Intro: Anagrams, a palindrome, and a letter bank regarding American presidents. A crossword without clues, by Lee Sallows. Mary Jane Heaster, Zona's mother. Sources for our feature on the Greenbrier Ghost: Katie Letcher Lyle, The Man Who Wanted Seven Wives, 1986. "The Greenbrier Ghost," West Virginia Division of Culture and History (accessed Sept. 22, 2018). David Jenkins, "Common Law, Mountain Music, and the Construction of Community Identity," Social & Legal Studies 19:3 (September 2010), 351-369. Joel Ebert, "Trials in High Profile," Charleston [W.V.] Sunday Gazette-Mail, Oct. 11, 2015, A.1. Joel Ebert, "Blankenship's Just One of Many High-Profile Trials in WV History," TCA Regional News, Oct. 11, 2015. Sandi Toksvig, "Ghosts Obviously Have Their Downsides, But at Least They Make Life Interesting," Sunday Telegraph, Jan. 23, 2011, 5. Mike Conley, "Ghost Brings Murderer to Justice," Marion [N.C.] McDowell News, Aug. 27, 2009. Allison Barker, "Courthouse Old Enough to Have Ghost in Its History," Charleston Sunday Gazette-Mail, March 9, 2003, 2B. Chris Stirewalt, "A Haunting Halloween," Charleston Daily Mail, Oct. 31, 2002, 1C. Michelle Saxton, "West Virginia's Hills Are Home to Ghostly Tales," Charleston Gazette, Oct. 30, 2000, 7A. Marina Hendricks, "Retelling a Greenbrier Ghost Tale," Charleston Sunday Gazette-Mail, Oct. 31. 1999, 1E. "Trial of Trout Shue," The Bar 11:2 (February 1904). "Foul Play Suspected," Greenbrier Independent, Feb. 25, 1897. "Foul Play Suspected," Staunton [Va.] Spectator and Vindicator, March 4, 1897. Garry Rodgers, "How a Ghost's Evidence Convicted a Murderer," Huffington Post, Feb. 19, 2017. Listener mail: Nic Fleming, "Hungry Cats Trick Owners With Baby Cry Mimicry," New Scientist, July 13, 2009 [contains audio files of urgent and non-urgent purrs]. Lynne Peeples, "Manipulative Meow: Cats Learn to Vocalize a Particular Sound to Train Their Human Companions," Scientific American, July 13, 2009. Karen McComb et al., "The Cry Embedded Within the Purr," Cell 19:13 (July 14, 2009), R507-R508. Mayo Clinic, "Toxoplasmosis," Oct. 3, 2017. Paul R. Torgerson and Pierpaolo Mastroiacovo, "The Global Burden of Congenital Toxoplasmosis: A Systematic Review," Bulletin of the World Health Organization 91 (2013), 501-508. Centers for Disease Control and Prevention, "Parasites - Toxoplasmosis (Toxoplasma Infection)" (accessed Sept. 26, 2018). Ed Yong, "Mind-Bending Parasite Permanently Quells Cat Fear in Mice," National Geographic, April 26, 2013. M. Berdoy et al., "Fatal Attraction in Rats Infected With Toxoplasma gondii," Proceedings of the Royal Society of London B: Biological Sciences 267:1452 (2000), 1591-1594. Karen Sugden et al., "Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence From a Population-Representative Birth Cohort," PLoS One 11:2 (2016), e0148435. Samuel Osborne, "Mind-Altering Parasite Spread by Cats Could Give Humans More Courage and Overcome 'Fear of Failure', Research Suggests," Independent, July 25, 2018. "The Myth of 'Mind-Altering Parasite' Toxoplasma Gondii?" Discover, Feb. 20, 2016. Jaroslav Flegr, "Effects of Toxoplasma on Human Behavior," Schizophrenia Bulletin 33:3 (2007), 757-760. B.D. Pearce et al., "The Relationship Between Toxoplasma gondii Infection and Mood Disorders in the Third National Health and Nutrition Survey," Biological Psychiatry 72:4 (2012), 290-295. Lucy Jones, "Ten Sinister Parasites That Control Their Hosts' Minds," BBC Earth, March 16, 2015. F. Thomas et al., "Biochemical and Histological Changes in the Brain of the Cricket Nemobius sylvestris Infected by the Manipulative Parasite Paragordius tricuspidatus (Nematomorpha)," International Journal for Parasitology 33:4 (2003), 435-443. Sandra B. Andersen et al., "The Life of a Dead Ant: The Expression of an Adaptive Extended Phenotype," American Naturalist 174:3 (2009), 424-433. Chris Reiber, "Change in Human Social Behavior in Response to a Common Vaccine," Annals of Epidemiology 20:10 (2010), 729-733. F. Solmi, et al., "Curiosity Killed the Cat: No Evidence of an Association Between Cat Ownership and Psychotic Symptoms at Ages 13 and 18 Years in a UK General Population Cohort," Psychological Medicine 47:9 (2017), 1659-1667. This week's lateral thinking puzzle was contributed by listener Ben Snitkoff. You can listen using the player above, download this episode directly, or subscribe on Google Podcasts, on Apple Podcasts, or via the RSS feed at https://futilitycloset.libsyn.com/rss. Please consider becoming a patron of Futility Closet -- you can choose the amount you want to pledge, and we've set up some rewards to help thank you for your support. You can also make a one-time donation on the Support Us page of the Futility Closet website. Many thanks to Doug Ross for the music in this episode. If you have any questions or comments you can reach us at podcast@futilitycloset.com. Thanks for listening!

Today we're talking mind-body medicine with James S. Gordon, MD, a Harvard educated psychiatrist, author, and world-renowned expert in using mind-body medicine to heal depression, anxiety, and psychological trauma. In 1991, he founded the Center for Mind-Body Medicine (CMBM), a 501(c)(3) nonprofit educational organization that has become a worldwide leader in making self-care, group support, and community-building central to all healthcare, the training of health professionals, and the education of children. Joining us to co-host this episode with me is Tatiana Znayenko-Miller, a student the MSHS Program in Integrative Medicine at GW. She is an intern at CMBM, functioning as the Clinical Research Coordinator. Dr. Gordon has created ground-breaking programs of comprehensive mind-body healing for physicians, medical students, and other health professionals; for people with cancer, depression and other chronic illnesses; for children and families traumatized by natural and man-made disasters; and for U.S. Military returning from Iraq and Afghanistan. He served as the first Chairman of the Program Advisory Council to NIH's Office of Alternative Medicine. And you were also the Chairman of the White House Commission on Complementary and Alternative Medicine Policy under Presidents Clinton and G.W. Bush. Register for a CMBM Online Mind-Body Skills Group with James S. Gordon, MD, on that will be held on Thursdays, 5:30-7:30 PM ET, beginning April 16, 2020. https://cmbm.regfox.com/application-to-join-james-s-gordon-md-online-mind-body-skills-group ◘ Related Links Center for Mind-Body Medicine https://cmbm.org/ TEDMED talk on "Fulfilling Trauma's Hidden Promise https://www.youtube.com/watch?v=UriA_Crzfl0 Even a single mindfulness meditation session can reduce anxiety. Experimental Biology, 2018. https://www.sciencedaily.com/releases/2018/04/180423135048.htm An Adapted, Four-Week Mind-Body Skills Group for Medical Students: Reducing Stress, Increasing Mindfulness, and Enhancing Self-Care. Explore: The Journal of Science and Healing, 2015. https://www.sciencedirect.com/science/article/pii/S1550830715000294 Alterations in Resting-State Functional Connectivity Link Mindfulness Meditation With Reduced Interleukin-6: A Randomized Controlled Trial. Biological Psychiatry, 2016. https://www.sciencedirect.com/science/article/pii/S0006322316000792 ◘ Transcript https://www.linkedin.com/pulse/transcript-finding-steadier-path-mind-body-medicine-gw-office-of/?published=t ◘ This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license. ◘ Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast. This week, the top managed care stories included President Donald Trump's plan to drive down drug prices; the FDA approved the first biosimilar of the year; a study found rapid uptake of PD-1 agents after FDA approval. Read more about the stories in this podcast: Trump Offers Blueprint to Drive Down Prescription Drug Prices; Targets Rebates, "Middlemen": www.ajmc.com/newsroom/-trump-offers-blueprint-to-drive-down-prescription-drug-prices-targets-rebates-middlemen Azar Stumps for Plan to Hold Down Prescription Drug Costs: www.ajmc.com/focus-of-the-week/azar-stumps-for-plan-to-hold-down-prescription-drug-costs FDA Approves Epoetin Alfa Biosimilar for Anemia: www.ajmc.com/newsroom/fda-approves-epoetin-alfa-biosimilar-for-anemia Study Finds Rapid Uptake of Anti–PD-1 Agents Following FDA Approval: www.ajmc.com/newsroom/study-finds-rapid-uptake-of-anti8211pd1-agents-following-fda-approval Researcher Details Microbiome Mysteries Connecting the Gut, Brain: www.ajmc.com/conferences/sobp-2018/researcher-details-microbiome-mysteries-connecting-the-gut-brain Society of Biological Psychiatry 73rd Annual Scientific Convention: www.ajmc.com/conferences/sobp-2018 American Thoracic Society 2018 International Conference: www.ajmc.com/conferences/ats-2018 ISPOR Annual Conference: http://www.ajmc.com/conferences/ispor-2018 Newsletter Signup: www.ajmc.com/email-profile