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Summer's here! It's time to bust out the new splashes and signature scents. Don't have a signature scent? Not to worry, we've got you covered with this lil' baby. It has a base fragrance of chicken sandwiches with top notes of zinc oxide and kolaches.Suggesting talking points: Beach Horse, You are the Splash, Kolache Church, High Coyote Activity, Richard StinkSupport AAPI communities and those affected by anti-Asian violence: https://www.gofundme.com/c/act/stop-aapi-hate For resources on anti-racism and fighting police violence: https://blacklivesmatters.carrd.co/
CLR Show 1557. Air Date May 24, 2021. As insane and easy a target as Marjorie Taylor Greene may be, Progressive Media has no right to mis-state or misinterpret her ramblings in order to make a Progressive political point on a given day. She did not make an anti-semitic remark on May 23rd. Suggesting she did––because it furthers a commentator's story line––does far more long-term harm to Progressives than it does to Trumpians.
You know what I’m very good at? Suggesting. Sometimes uninvited suggestions, because when my people are in something – a crisis, heartache, problem – I think they must be telling me so I can share with them how to get out of it. My heart hurts so much for them that I want nothing more Continue reading → The post How To Be There For Someone And What Keeps Us From Telling Our Stories appeared first on No One Told Me Podcast.
Jon Jennings is the Founder and Managing Partner of Jennings Executive Search, LLC. He began his career with a boutique recruiting firm, building relationships with C-Level accounting and finance professionals utilizing a research-based approach of study and analysis to best serve his clients. In 2012, Jon took this approach to a larger firm where he worked with several CFOs to build entire accounting and finance departments and gain a large firm perspective in how to build a successful practice. This experience led to the creation of Jennings Executive Search, LLC. In this episode, Jon talks about how he matches pricing talents depending on a strategy the company uses and each company’s preferences, what screening process he uses when looking for pricing people. He also shares how he guides companies in choosing the best pricing leader they can get as sometimes they don’t know what they are looking for. He also emphasizes on skill sets a pricing person should develop and acquire early on as he starts to elevate his career along the way. Why you have to check out today’s podcast: Learn how to build out your skillset as a pricing person so you get more relevant in today’s competitive world of pricing Find someone who knows Pricing people if you are looking to hire Pricing leaders Discover how to find Pricing people that match your company’s strategies to get a good fit to impact the business “Think about what you're leaving on the table. If you're not trying to be creative around pricing, you're losing. If you're not thinking about ways to add some sort of dynamic element in trying to find ways to increase profitability from that standpoint, then someone else is.” - Jon Jennings Topics Covered: 01:39 - How he got into Pricing 03:15 - What do they focus on when hiring Pricing people 03:50 - How the company’s strategy matter when hiring Pricing people 05:42 - Delineation of roles among Pricing analyst, the VP, and the middle level 07:03 - HIs screening when looking for Pricing leaders 08:37 - How they provide guidance to companies when looking for Pricing leaders 09:39 - Building off of the job description, value-based principles, and the roadmap of the company to find potential Pricing leaders 11:53 - How he helps clients find Pricing people 13:49 - Starting with questions to convince a company to hire a pricing person 15:10 - Suggesting to companies to listen to Impact Pricing 15:32 - How value-based pricing makes sense in the world of recruitment 16:48 - Skillset you need to build as a pricing person early on in your career 18:16 - What more you can do to expand your capabilities as a Pricing person 19:40 - Beg, borrow and steal 20:44 - Be a driver and not a whiner 21:06 - Are pricing people well compensated 22:37 - Setting differentiators for Pricing persons to match with client companies preferences 23:48 - Setting expectations for yourself and executing it 25:20 - The strengths and weaknesses of a consulting talent 27:15 - HIs impactful advice to help you in your business Key Takeaways: “Our job is to find people who make impacts with fitting culturally and have a history of really impacting the business.” - Jon Jennings “It's really about me kind of telling them [client companies] a story, and asking questions to see if I can guide them to a more dynamic solution if they're not already there.” - Jon Jennings “I always start with questions. Because I can't give advice without context.” - Jon Jennings “If I'm advising someone, I have to build out their skill set. There's a couple of elements that you want especially nowadays. Get into as much data science as you can, teach yourself coding. It doesn't matter, as you get to higher levels, obviously, you're not going to utilize that as much, but you're going to still use that a little bit.” - Jon Jennings “As you move up the organization, it's about reaching out across company lines, and not being afraid to go talk to the marketing person, pick people's brains. Try to expand that knowledge as much as you can and just always be learning. That's how you can elevate your career.” - Jon Jennings “Be a driver. Don't be afraid to challenge above you. If you believe in your concept, just be the squeaky wheel until you get some traction.” - Jon Jennings “Being mindful of constantly trying to improve your strategy and looking at competitive advantage and all different elements is 100% key.” - Jon Jennings Resources / People mentioned: Professional Pricing Society McKinsey BCG Connect with Jon Jennings: www.jenningsexec.com LinkedIn Email: jon@jenningsexec.com Connect with Mark Stiving: Email: mark@impactpricing.com LinkedIn
Famed Tech Venture Capitalist wrote a post back in 2010 titled 'No Conflict, No Interest'. Suggesting that sometimes the trade off of having people interested and invested in your thing is that they may have a conflict of interest. But that's ok. At least they're interested! And that means they will hopefully have some knowledge, skills, experience and abilities in areas specifically related to your thing. As long as there is integrity, a conflict of interest doesn't have to be damaging. So don't worry too much about avoiding conflicts of interest. First, worry about getting the interest. #conflictofinterest #integrity #transparency
Nick Prouten, LODE Project Ambassador, enlightens on the power and security of blockchain and bitcoin. (www.lode.one) Describing the current financial environment as a “wild west” digital transformation, Nicholas explains how blockchain and bitcoin offer nothing less than the transparency of finance and the democratization of money. Suggesting there is always a need for a universal 3rd good to demonstrate the value of money, he explains how the LODE AUX and AGX coins do just that by providing tokens linked to the value of 1 ounce of precious metals. Along the way we chat about PayPal, Elon Musk, Doomsday, and parrots.
Welcome to the Elevator World News Podcast. Today’s podcast news podcast is sponsored by elevatorbooks.com: www.elevatorbooks.com THYSSENKRUPP ELEVATOR BECOMES TK ELEVATOR; BRANDED TKE thyssenkrupp Elevator is now TK Elevator, branded TKE, the company announced on February 25. The new name and brand follows the company's becoming a standalone entity following its purchase by a consortium of Advent, Cinven and RAG AG in February 2020. Suggesting the energy and optimism of a sunrise, the purple and orange colors and bold appearance of the new logo points to the company's aspirations, TKE explained. "The new TKE brand is. . . a great opportunity to strengthen our market positioning and technology leadership in next-generation mobility services, TKE CEO Peter Walker said. “With the recent integration of our cloud-based digital platform MAX into all kinds of new elevator and escalator systems, we have made a significant step toward digitalization of our products and services." Image credit: courtesy of TKE To read the full transcript of today's podcast, visit: elevatorworld.com/news Subscribe to the Podcast: iTunes │ Google Play | SoundCloud │ Stitcher │ TuneIn
When was the last time you said no to someone! Do you find it hard to say no and feel guilty when you do? Unfortunately, it is a common occurrence for many people. If you do are one of these people, it is essential that you learn how to say no and not feel guilty when you do. Firstly, why is it hard for you to say no? Is it because you are afraid of what other people will say or think of you? Are you worried that your refusal to help them could affect how they treat you and maybe even ruin your friendship or relationship? The problem is if you keep on saying yes, many people will take advantage of you, and it will burn you out emotionally. This doesn’t mean that they are necessarily bad, but most people will take the least resistance path. So if you can always be relied on to say yes, you will be the one who is always assumed will do the things no one else wants to. Remember that saying no doesn’t necessarily mean that you don’t want to help. Sometimes you can’t do it because you’re busy and have other tasks of your own to prioritize. So, don’t feel guilty when you have to say no. Here are some tips on how you can say no and stop feeling guilty about it. Offer An Alternative When you can’t help by saying yes, one of the best ways you can do so is by giving an alternative solution. For instance, if you’re not available to accompany your best friend this week because your schedule is full, try to offer a time the following week. Suggesting an alternative is an excellent way to show that you want to help, even if your current situation won’t allow you. Don’t Beat Around The Bush If you have to say no, just say it, direct and short. In many situations, you should not be required to offer an explanation. The more excuses that you give, the more you give hope to the other person. You will also be giving them the power to continue asking you until you give in. Don’t beat around the bush and let them know that you really can’t do what they want right now. Establish Boundaries Early On One of the best things that will help you not feel guilty every time you have to say no is to set boundaries. Evaluate what you stand for, your role in the relationship, and why you are saying no. For instance, if you’ve set a price for your service and a prospective client offers you less than what you expect, you don’t have to feel obliged to accept. If it’s non-negotiable, politely decline because it’s outside of your pre-determined boundaries. Be Assertive Without Being Aggressive When you say you can’t or don’t want to fulfil a request, be firm about it even when they insist. You have to be assertive and take power by saying you’ll let them know when you can help them. You may have to repeat yourself several times, but stick to your basic answer. Try not to engage if they keep asking you questions or trying to negotiate with you to get you to comply. Think About Yourself First Most often, you’re not saying no just because you want to be contrary. Usually, you’re really swamped with work, or you’re too tired to do anything. So, it’s okay to think about yourself first. Sometimes you have to be selfish for your good. Before you say yes, think about how it can affect your personal situation, health, and well-being. You have to say no, especially when you have to take care of yourself first. If you are not well, how can you do more for others? Don’t Apologize It may take a lot of practice, but try not to apologize every time you have to say no to someone asking you for something. When you apologize, it makes you feel guilty even when there’s nothing to feel wrong about. Of course, you don’t have to be rude. You may be finding it hard to say no when someone asks you anything, but learning to do so is an essential life skill. For the sake of your own mental health, you have to think about yourself first, what you stand for, and what your priorities are...... Learn more: https://mentalhealthtraining.info/
BONUS EPISODE !!! : ) So here we go ! If you are interested in this incredible paradoxical universally elusive answer as to which came first ... I invite you to dive into todays episode ! If you can hang with me till the end we are going to have quite a bit of fun and maybe even gain some clarity on the question !! Humans ask.... Which came first ..???? The Brain ( or physical matter ).. or Consciousness ( Awareness , God, Universal Energy ). Materialists say that they are searching for evidence ( some say they've found it but it hasn't been proven)... That our conscious state of awareness .. the "self aware" ( and aware of the "other" ) experience is a generation of physical processes inside of and by the brain ... that without the brain consciousness would not exist .. and that physical matter was around WELL before our ability to perceive it with our "conscious" selves... The other end says that Consciousness ... GAVE RISE to the physical experience .. or physical matter ... That there is a powerful Vibrational or God Force that has always been and always will be.. and from it ... physical matter arose and now exists.... ( this is really an argument for or against a God ) One side is looking to measure and determine with evidence to disprove the "woo woo" idea that there is a Universal power beyond "US"... that Spirituality is an illusion of physical processes and doesn't or shouldn't be considered as a "supernatural" or religious experience .... And the other side is saying that the physical experience itself and the "creation" of it is all because of this amazing non physical energy ... and that without this God Consciousness , physical beings or particles wouldn't even be here ..... and that the physical experience we perceive is in fact the illusion ........ Neither will ever be able to be proven to the other .... Even if science finds that your awareness IS generated by the brain .... The ENTIRE physical process of evolution that lead to that scientist that found that "evidence" .... WILL not matter because the evidence of the process and the evidence itself .... Would need to be experienced in the Awareness of the scientist and the humans that consider it in order for it to exist at all .... Suggesting the opposite ... that the physical proof... could only matter ... if it arises in the AWARENESS or consciousness of the observer ... and it will go on and on and on .... Both are necessary for each other to exist ... This is a dualistic Universe and energetic experience ... and inside this episode .. We dive deep into how that can benefit us ALL .. : ). SO MUCH LOVE TO YOU TODAY !!!! -----------------------------------------------------------------!! Enrollment for The Next Conscious Mentorship Program is Open and I am so excited for this round ! Click Below For More Information On This Journey ! The Alchemist 1:1 Conscious Alignment Program ~Hello !!! I help humans Navigate their Awakening and Consciously Align in ALL areas of their Life. ARE YOU LOOKING TO APPLY THIS? Click Here: 3 Ways To Work With Me ~ Support the podcast through Patreon : ) THANK YOU !! to all who do !! I am so grateful ! https://www.patreon.com/user?u=22969209
In this episode, The Collaborative hosts Dr. Katherine Troyer (Assistant Director) and Dr. Lauren Malone (Academic Technologist) explore how our lectures can become something that students don't just tolerate but are actually excited to experience in our courses. Suggesting that the key is to build in student buy-in, we talk about switching around the order of our class periods (think of lectures as dessert!), harnessing the power of storytelling, and incorporating active learning into our lectures.
Join your host Kevin McDonnel as he discusses this weeks property news. Landlord today has named London as the city with the highest rent in the UK with an average of £1435 a month in comparison to the North East where the average rent was £490 a month. Property investor today analysed how Brexit will affect the UK's housing marketer and Kevin discusses news closer to home as he finds out what has been happening in the Progressive Property community. KEY TAKEAWAYS Weekly Property News On the Landlord today website they have reported that rentals have hit an all-time high according to government figures. The average monthly private sector rent in England for September was £725. This figure was the highest ever reported by the office of national statistics. There were regional differences with London being the highest at £1435 monthly and the North East the lowest at £490 monthly. Property Investor Today stated that the UK has been ranked top hot spot for overseas residential investments post-Brexit. Suggesting the UK real estate market will remain firmly open for business post Brexit. The findings from the European global real estate survey by international law firm DLA Piper found that overall, the top 5 countries for investment are all in Europe with the UK leading the way with 33% followed by France 28%, Germany 25%, Spain 24% and Italy 18%. Many people think there is going to be a housing crisis after Brexit however, these statistics prove otherwise. Currently, businesses have to register for VAT only if they make over £85,000 per year. However, UK digital platforms combined are forecast to have as much revenue as £140bn a year by 2025. Much of this will be untaxed because it is secured by small scale individual operators who individually have less than £85,000 of turnover. This means if the government decided to charge VAT to Air BnB's then if you as an individual has a turnover under £85,000 decide to put your property on Air BnB, Air BnB will be charged VAT on their income which will be significantly above the £85,000 of you the individual. Air BnB will have to pass that cost onto you. Progressive Property Community News & Discussions Should you buy property now or should you wait until next year should there be a crash in the market? Instead of asking yourself this, ask “What can I do now to find the very best possible deals that are available right now”. You make more money in property in a market that is going down and in recession type market than you ever do in a rising market. Why? Because in a rising market, the homeowner can sell to anybody they like. In a market like a recession, it becomes a buyers market. Property investors should always be buying. BEST MOMENTS “It is really interesting that rent has actually increased during the pandemic.” “This is really important data for us as property investors.” “There is still a significant profit margin in Air BnB” SUBSCRIBE TO THE A NEW INVESTMENT SERIES Episode One:How to Perfectly Invest £10,000 | The Best Stocks | Property | Gold & Classic Cars Watch Live On The Progressive Property YouTube Channel Every Monday At 7 PM Tiny.cc/PPTV Listen To Audio Recordings On The Money Podcast bit.ly/moneypodcastitunes ABOUT THE HOST Kevin McDonnell is a Speaker, Author, Mentor & Professional Property Investor. He is an expert when it comes to creative property investment strategies. His book No Money Down: Property Invest talks about how to control and cash flow other people's property to create financial freedom. CONTACT METHOD https://www.facebook.com/kevinMcDonnellProperty/ https://kevinmcdonnell.co.uk/ See omnystudio.com/listener for privacy information.
Paul J. Wang: Welcome to the monthly podcast! On the Beat for Circulation: Arrhythmia and Electrophysiology. I'm Dr. Paul Wang, Editor-in-Chief. With some of the key highlights from this month's issue. Paul J. Wang: In our first paper, Demilade Adedinsewo and associates assess the accuracy of an artificial intelligence-enabled electrocardiogram [AI-ECG] to identify patients presenting with dyspnea who have left ventricular LV systolic function (defined as LV ejection fraction ≤35%) in the emergency department [ED]. Patients were included if they had at least one standard 12-lead electrocardiogram [ECG] acquired on the date of the ED visit and an echocardiogram performed within 30 days of presentation. Patients with prior LV systolic dysfunction were excluded. A total of 1,606 patients were included. Meantime from ECG echocardiogram was one day. The AI-ECG algorithm identified LV systolic dysfunction with an area under the curve [AUC] of 0.89 and accuracy of 85.9%. Sensitivity was 74%, specificity 87%, negative predictive value 97%, and positive predictive value 40%. To identify an ejection fraction less than 50%, the AUC was 0.85, sensitivity 86%, sensitivity 63%, and specificity 91%. NT-proBNP alone with a cutoff greater than 800 identified LV systolic function with an AUC of 0.80 by comparison. Paul J. Wang: In our next paper, Mahmood Alhusseini and associates hypothesize that convolutional neural networks [CNN] may enable objective analysis of intracardiac activation in atrial fibrillation [AF]. They perform panoramic recording of bi-atrial electrical signals in AF and use the Hilbert-transform to produce 175,000 image grids in 35 patients labeled for a rotational activation by experts who showed consistency, but with variability (kappa [κ]=0.79). In each patient, ablation terminated atrial fibrillation. A CNN was developed and trained on 100,000 AF image grids validated on 25,000 grids, and then tested on a separate 50,000 grids. They found in a separate test cohort of 50,000 grids, CNN reproducibly classified AF image grids into those with or without rotational sites with 95.0% accuracy. This accuracy exceeded that of support vector machines, traditional linear discriminant, and k-nearest neighbor statistical analyses. To probe the CNN, they applied gradient weighted class activation mapping, which revealed that the decision logic closely mimicked rules used by experts (C statistic 0.96). The authors concluded that convolutional neural networks improve the classification of intercardiac AF maps compared to other analyses and agreed with expert evaluation. Paul J. Wang: In our next paper, Kenji Okubo and associates examined whether late potential LP, abolition and ventricular tachycardia [VT] non-inclusive ability predicted long-term outcomes in patients with non-ischemic cardiomyopathy [NICM] undergoing VT ablation. The total 403 patients with NICM (523 procedures) who underwent VT ablation from 2010 to 2016 were included. The underlying structural disease consists of dilated cardiomyopathy (DCM, 49%), arrhythmogenic right ventricular cardiomyopathy (ARVD 17%), postmyocarditis (14%), valvular heart disease (8%), congenital heart disease (2%), hypertrophic cardiomyopathy (2%), and others (5%). Epicardial access was performed in 57% of patients. At baseline, the LPs were present in 60% of patients, and a VT was either inducible or sustained/incessant in 85% of the cases. At the end of the procedure LP abolition was achieved in 79% of cases in VT noninducability in 80%. After a multivariate analysis, the combination of LP abolition and VT noninducibility was independently associated with free survival from VT (hazard ratio, 0.45, p = 0.0002) and cardiac death (hazard ratio 0.38, P = 0.005). The benefit of LP abolition of preventing the VT recurrence in ARVD and postmyocarditis appeared superior to that observed for DCM. Paul J. Wang: In our next paper, Domenico Corradi, Jeffrey Saffitz and associates hypothesize that structural molecular changes in atrial myocardium that correlate with myocardial injury and precede and predict postoperative atrial fibrillation [POAF] may identify new molecular pathways and targets for prevention of this common morbid complication. Right atrial appendage [RAA] samples were prospectively collected during cardiac surgery from 239 patients enrolled in the OPERA trial. 35.2% of patients experienced POAF compared to the non-POAF group. They were significantly older and more likely to have chronic obstructive pulmonary disease or heart failure. They had a higher Euro score and more often underwent valve surgery. No differences in atrial size were observed between POAF and non-POAF patients. The extent of atrial interstitial fibrosis, cardiomyocyte myocytolysis, cardiomyocyte diameter, glycogen storage, or connection 43 distribution at the time of surgery, was not significantly associated with the incidents of POAF. None of these histopathological abnormalities were correlated with level of NT pro-BNP, hs-cTnT, CRP, or oxidative stress biomarkers. The authors concluded that in sinus rhythm patients undergoing cardiac surgery, histopathological changes in RAA do not predict POAF. They did not also correlate with biomarkers of cardiac function, inflammation, and oxidative stress. Paul J. Wang: In our next paper, Mark McCauley, Liang Hong, Arvind Sridhar, and associates hypothesize that obesity decreases sodium channel NAF 1.5 expression via enhanced oxidative stress, thus reducing the sodium current and enhancing susceptibility to atrial fibrillation [AF]. They studied a diet induced obese [DIO] mouse model. Pacing induced AF in 100% of DIO mice versus 25% in controls (P 20 ms shorter than the other sites, and/or induction of AF/atrial tachycardia during measurements. LVA ablation was performed in the LA-LVA patients during the follow-up period of a mean of 62 weeks, the EP test-guided group had a significantly lower recurrence rate (19%,11/57 versus 41%, 22/54, P=0.012) and a higher Kaplan-Meier AF/AT-free survival curve compared with controls (P=0.01). No significant differences in the recurrence, and AF/AT-free survival curves between PWI (positive EP test) and non-PWI (negative EP test) subgroups were observed. Therefore, PWI for positive EP tests reduced the AF/AT recurrence in the EP test-guided group. A stepwise Cox proportional hazard analysis identified EP test-guided ablation as a factor, reducing recurrence rates. The recurrence rates in LA-LVA ablation group and EP test-guided group were similar. Paul J. Wang: In our next study, Jinxuan Lin and associates assess whether simultaneous pacing of the left and right bundle branch areas may achieve more synchronous ventricular activation than just bundle pacing alone. In symptomatic bradycardia patients, the distal electrode of the bipolar pacing lead was placed at the left bundle branch area via a transventricular-septal approach. This was used to pace the left bundle branch area, while the ring electrode was used to pace the right bundle branch area. Bilateral bundle branch area pacing [BBBP] was achieved by stimulating the cathode and anode in various configurations. BBBP was successfully performed in 22 out of 36 patients. Compared with LBBP, BBBP resulted in greater shortening of QRS duration (109.3 vs 118.4 ms, P < 0.001). LBBP resulted in paced RBBB configuration with a DRVAT of 115 ms and interventricular conduction delay of 34.0 ms. BBBP fully resolved the RBBB morphology in 18 patients. In the remaining 4 patients, RBBP pacing partially corrected the right bundle branch block. Paul J. Wang: In our next paper, Ramanathan Parameswaran, Jonathan Kalman, Geoffrey Lee and associates recorded 2-minute long segments of simultaneous inter-operative mapping of endo- and epicardial lateral right atrial [RA] wall in patients with persistent atrial fibrillation [AF] using 2 high-density grid catheters (16 electrodes, 3 mm spacing). Filtered unipolar and bipolar electrograms [EGMS] of continuous 2-minute AF recordings and electrodes locations were exported for phase analysis. They defined endocardial-epicardial dissociation [EED] as phase differences of ≥20 ms between paired endo- and epi electrodes. Wavefronts [WF] were classified as single rotations, that is single wavefront, focal waves, or disorganized activity as per standard criteria. Endo-Epi wave fronts were simultaneously compared on dynamic phase maps. Complex fractionated electrograms were defined as bipolar electrograms with directional changes occupying at least 70% of the sample area. 14 patients with persistent AF underwent cardiac surgery are included. EED was seen in 50.3% of phase maps with significant temporal heterogeneity. Disorganized activity (endo 41.3%, epi 46.8%, P = 0.0194) and single wave (endo 31.3 versus epi 28.1, P = 0.129) were the dominant patterns. Transient rotations (endo 22%, epi 19.2%, P = 0.169, mean duration 590 ms) and non-sustained focal waves (endo 1.2% and epi 1.6%, P = 0.669) were also observed. Apparent transmural migration of rotational activations (n=6) from the epi- to the endocardium was seen in 2 patients. EGM fractionation was significantly higher in the epicardium than endocardium (61.2% versus 51.6%, P < 0.0001). The authors concluded that simultaneous endo-epi phase mapping of prolonged human persistent AF recordings showed significant EED marked temporal heterogeneity, discordant and transitioning wavefronts patterns and complex fractionations. No sustained focal activity was observed. Such complex 3-dimensional interactions provide insights into why endocardial mapping alone may not fully characterize the AF mechanism and why endocardial ablation may not be sufficient. Paul J. Wang: In our next paper, Andrew Beaser and associates hypothesize that intravascular ultrasound [IVUS] could accurately visualize and quantify intravascular lead adherence and degree of intravascular lead adherence correlates with transvenous lead extraction difficulty. Serial imaging of leads occurred prior to transvenous lead extraction using IVUS. Intravascular lead adherence areas were classified as high or low grade. Degree of extraction difficulty was assessed using 2 metrics and correlated with intravascular lead adherence grade. Lead extraction difficulty was calculated for each patient and compared to IVUS findings. 158 vascular segments in 60 patients were analyzed: 141 (89%) low grade versus 17 (11%) high grade. Median extraction time (low = 0 versus high grade 97 seconds, P < 0.001) and median laser pulsations delivered (low = zero versus high grade 5,852, P < 0.001) were significantly higher in the high-grade segments. Most patients with low lead extraction difficulty score had low intravascular lead adherence grades. 86% of patients with high lead extraction difficulty score had low IVUS grade, and the degree of transvenous lead extraction difficulty was similar to patients with low IVUS grades and lead extraction difficulty scores. Paul J. Wang: In our next paper, András Bratincsák, and associates sought to create the foundation of normative ECG standards in the young using Z-scores. 102 ECG variables were collected from a retrospective cohort of 27,085 study subjects with no known heart conditions, age zero to 39 years. The cohort was divided into 16 age groups by gender. Median interquartile range and range were calculated for each variable adjusted to body surface area. Normative standards were developed for all 102 ECG variables, including heart rate; P, R, and T axis; R-T axis deviation; PR interval, QS duration, QT, and QTc interval; P, Q, R, S, and T amplitudes in 12 leads; as well as QRS and T wave integrals. Incremental Z-score values between negative 2.5 and 2.5 were calculated to establish the upper and lower limits of normal. Historical ECG interpretive concepts were reassessed and new concepts observed. The author summarized that electronically acquired ECG values based on the largest pediatric and young adult cohort ever compiled provide the first detailed, standardized, quantitative foundation of traditional and novel ECG variables. Paul J. Wang: In our next paper, Jungmin Hwang and associates hypothesize that suppressing the late sodium current may counterbalance the reduced repolarization reserve in long QT syndrome [LQTS] and prevent early depolarization [EAD] and polymorphic ventricular tachycardia [PVT]. They tested the effects of selective late sodium channel blocker GS967 on polymorphic ventricular tachycardia [PVT] induction in a transgenic rabbit model of type two using intact heart optical mapping, cellular electrophysiology, and confocal calcium imaging and computer modeling. They found that GS967 reduced ventricular fibrillation [VF] induction under a rapid pacing protocol (7 out of 14 hearts in control versus 1 out of 14 at 100 nanomolar) without altering action potential duration [APD] or restitution and dispersion. GS967 suppressed PVT incidents by reducing calcium mediated EADs and focal activity during isoproterenol perfusion (at 30 nanomolar, 7 out of 12 and a 100 nanomolar, 8 out of 12 without EADs and PVTs). Confocal calcium imaging of LQT myocytes revealed GS967 shortened calcium transient duration by accelerating sodium calcium exchanger mediated calcium efflux from cytosol, thereby reducing EADs. Computer modeling revealed the inward late sodium current potentiates EADs in the LQT setting through providing additional depolarizing currents through action potential plateau phase, and increasing intracellular sodium that decreases the depolarizing sodium calcium exchanger, thereby suppressing the action potential plateau and delaying the activation of slowly activating delayed rectifier current, IKS. Suggesting important roles in the late sodium current in regulating intracellular sodium. Thus, the authors concluded that selective late sodium channel blockade by GS967 prevents EADs and abolishes PVT in LQT rabbits by counterbalancing the reduced repolarization reserve and normalizing intracellular sodium. Paul J. Wang: In our next paper, Pietro Lazzerini, Mohamed Boutjdir and associates, hypothesize that systemic inflammation per se can significantly prolong QTc during infection via cytokine-mediated changes in potassium channel expression. They found in patients with acute infections, regardless of concomitant QT-prolonging anti-microbial therapy, QTc was significantly prolonged but rapidly normalized in parallel to C-reactive protein [CRP] and cytokine level reduction. Consistently, in Torsades de Pointes cohort, concomitant acute infections were prevalent 30% despite only a minority (25%) of these cases were treated with QT-prolonging anti-microbials. KCN J2, potassium channel expression in peripheral blood mononuclear cells was strongly correlated to that in ventricles, inversely associated to CRP and interleukin one changes in acute infection patients. The authors concluded that acute infection, systemic inflammation rapidly induces cytokine-mediated ventricular electrical remodeling and significant QTc prolongation, regardless of concomitant antimicrobial therapy. Paul J. Wang: In a research letter, Christophe Beyls and associates examined the risk of bradycardia and critically ill COVID-19 patients treated with Lopinavir [LPV], a protease inhibitor of HIV-1, and Ritonavir [RTV], another protease inhibitor that strongly inhibits hepatic cytochrome P 450 [CYP3A4] activity in order to increase the Lopinavir plasma concentration. During the first month of the outbreak, patients admitted to the ICU with positive PCR for COVID-19 received LPV (200 mg)/RVT (50 mg) twice daily for 10 days. Bradycardia was defined as heart rate below 60 for a period of more than 24 hours. All patients were monitored 24 hours a day for all hemodynamic parameters, including heart rate with a five-lead ECG. Monitors were linked to a computerized system allowing to extract hemodynamic data. LPV/RTV plasma concentration was monitored using analytic method, combining high propensity performance, liquid chromatography and tandem mass spectrometry at 72 hours and every 72 hours. They prospectively included 41 COVID-19 patients who received LPV/RTV treatment. Nine or 22% patients experienced bradycardia. No patients had a pre-existing nodal pathology on the ECG on admission. Among the 9 patients with bradycardia, 8 or 88% were sinus bradycardia and one (12%) third-degree AV block. Causality may be considered as bradycardia occurred at least 48 hours after LPV/RTV initiation, bradycardia resolved after discontinuation or dose reduction and no alternative cause was found. Patients who presented with bradycardia were older, had a higher RTV plasma concentration and a lower lymphocyte count. In our study, no correlation was found between RTV plasma concentration, LPV plasma concentration, and mean heart rate at day three. No patient had bradycardia in the first 48 hours after LPV/RTV administration. For patients with LPV RTV plasma level overdose, the dose of LPV RTV was divided by two until the next dose. For the patient with third degree AV block LPV/RTV was stopped. None of the patients had any known cytochrome CYP3A4-inhibiting drugs. The authors concluded that the results suggest that RTV plasma overdose in elderly critical ill patients may increase the risk of bradycardia. Paul J. Wang: In a research letter, Emily Zeitler and associates surveyed cardiac implantable device [CID] patients. A total of 109 patients were approached to participate, nine declined. Most respondents were white (79%), male (60%) with a mean age of 73 years. The median number of correct responses to the 11 factual questions was six. Respondents held some common misconceptions. For example, 25% of respondents believe that FDA determines the cost of the device. Trust in the FDA was high; 67% of respondents agreed "I trust the FDA". Respondents mostly agreed "the FDA would not approve my device unless it was a hundred percent safe". Only 6% of respondents agreed, "we would be better off if there was no FDA," and a similarly small fraction disagreed with "when it comes to medical devices, the U.S. does the best job in the world at keeping people safe". Most respondents, 69% demonstrated fear of device recalls by agreeing with "if there was a recall of all are part of my device, I think I would be worried or scared." On average, respondents were comfortable sacrificing some privacy for device surveillance, 75% agreed with "once the device has been approved, the FDA should continue to monitor for signs that there are problems with the device even if it means that private health information about me is collected". Respondents seemed to believe that the FDA was risk averse; 56% believed that the FDA does not approve devices unless they're a hundred percent safe. This is in contrast to trends shifting the demonstration of safety to post-approval settings and expanding acceptable forms of data for regulatory approval. Paul J. Wang: In a research letter, Laura Rottner, Christoph Sinning and associates examined novel high resolution imaging system based on a wide band dielectric technology, and reports the first clinical experience of feasibility and reliability of cryoballoon [CB] occlusion tool as compared to fluoroscopic and 3D transesophogeal [TEE] assessment during pulmonary vein isolation [PVI]. In consecutive patients with symptomatic atrial fibrillation [AF], cryoballoon-based ablation was performed with a novel 3D wide-band dielectric imaging system. Pulmonary vein [PV] occlusion was assessed with fluoroscopy in 3D-TEE and concomitantly correlated with the novel CB occlusion tool. The endpoint was defined as persistent PV isolation verified by spiral mapping catheter recordings 30 minutes after the last CB application. A total of 36 (90%) of PVs in 10 patients with paroxysmal (40%) and persistent (60%) were analyzed. In all patients, a normal PV anatomy with four separate PVs was documented. Visualization via 3D-TEE was feasible in 80% septal PVs and 100% of lateral PVs. In 67% of PVs, total PV occlusion was confirmed by all 3 imaging modalities. In 17% of PVs, incomplete PV occlusion was initially demonstrated by TEE and 3D dielectric imaging, whereas fluoroscopy suggested complete occlusion in initial analysis. After repositioning of the CB at 3 PVs, complete PV occlusion was verified by all three modalities. In 3 out of 36 (8%), no occlusion was initially seen by any imaging modality, for which the CB was repositioned resulting in total PV occlusion as confirmed by all three modalities. Two out of 36 PVs (6%) were confirmed to be occluded via fluoroscopy in 3D-TEE, but not by the CB occlusion tool. There was only one out of 36 PVs (3%), which were confirmed to be included by the CB tool and 3D-TEE, but not by fluoroscopy. A negative and positive predictive value of 1.0 and 0.6 was seen when comparing PV occlusion by the novel occlusion tool compared to PV collusion, verified by fluoroscopy and 3D-TEE. Paul J. Wang: In a special report, Jun Hirokami, and associates aim to clarify the spatial correlations between fractionated potential detected by Lumipoint with non-PV trigger. They enrolled 30 symptomatic atrial fibrillation [AF] patients who underwent non pulmonary vein [PV] foci ablation. 4 patients underwent the first procedure, 17 underwent second procedure and eight underwent third procedure, and one underwent a fourth procedure. They highlighted the fractionated signal area in atrial muscle [FAAM] during sinus rhythm and atrial pacing, thereby producing a digital FAAM map. They retrospectively applied Lumipoint to 30 patients in order to clarify the relationship between FAAM and non-pulmonary vein [PV] foci. Non-PV foci were successfully identified in all patients. They identified four patients with multiple non-PV foci. Of these four patients, one had non-PV foci at the superior vena cava and left arterial anterior wall. One had non-PV foci at the SVC and LA bottom wall. And two had non-PV foci at the SVC and interatrial septum. They only analyze 30 non-PV foci unrelated to SVC because the SVC isolation was routinely performed for non-PVC foci at the SVC. In order to analyze the correlation between FAAM and location of non-PV triggers, they determined the cutoff points of peaks slider, which non-PV triggers were completely located within the FAAM in. The accuracy of predicting location of the non-PV triggers was summarized using area under the receiver operating curve, a UROC curve. The optimal cutoff point of peak sliders to predict the location of non-PV was determined by the Youden Index. The Youden Index established the optimal cutoff point of the maximum peaks slider was 7; sensitivity was 0.906 and specificity 0.770. The peaks slider 7 was the most accurate predictor fractionated signals location area to the location of non-PV triggers. (area under the curve 0.902). The mean area of peaks slider 7 was six centimeters squared or 4.3% of the atrium. The authors concluded that the proof-of-concept observational study demonstrated that novel visualization tool of FAAM map successfully identified non-PV triggers that did not induce atrial fibrillation and/or non-PV foci, which potentially serve as substrates for AF maintenance. Paul J. Wang: In a special report, Leslie Saxon and associates update their prior publication providing further detail on mitigation adoption rates for the entirety of the U.S. patient population with implanted cardiac rhythm management devices falling under FDA cyber security advisories from any device manufacturer. They also provided limited data on known cybersecurity mitigation adoption outside the U.S. They report a unique complication resulting for introducing firmware to already implanted devices. Discuss how evolving FDA policies towards firmware mitigation adoption may increasingly determine how and when updates occur. They found that patients under 50 years of age and those over 80 years were less likely to receive the software upgrades, and male versus females had greater rates of upgrades. The upgrade rates varied according to U.S. Region and date of implant. Resynchronization devices were less likely to receive the upgrade, as were pacemaker dependent patient. Those ICD patients initially falling under the battery advisers were upgraded more frequently. The number of advisory patients followed in clinic was a significant predictor for firmware upgrade adoption, particularly for pacemakers that were often upgraded in smaller size clinics. Overall, only 24% of devices for all groups, and 22% of devices not impacted by the battery advisory were upgraded. For Abbott devices, the home communicator cyber security vulnerabilities were mitigated with an automatic software patch that was updated using the Merlin network, and adoption rates were nearly a hundred percent. For the entire patient cohort with impacted pacemaker and ICDs, U.S. and global adoption rates remain low at 24 to 35% with a low rate of complications. Most reported complications for pacemakers and ICD were symptoms (transient palpitations, dizziness, or syncope) that resulted from the temporary change in mode to VVI or transient loss of programmer telemetry while performing the upgrade (pacemaker 0.05%; ICD 0.01%). Globally, a total of 9 pacemakers and 8 ICDs required replacement, as a result of performing the firmware upgrade due to irreversible reversion to a backup pacing mode and loss of defibrillation therapy (ICDs). Analysis of the returned ICD pulse generaotrs found at 7 cases, the cause related to a capacitor bond failure that was exposed only when extended telemetry as required by the upgrade. The failure mechanism was an isolated component failure in the remaining ICD. The programmer based test has recently been FDA approved and can be performed prior to firmware upgrade to identify ICD patients at risk for capacitor bond failure. A total of 256 ICDs were susceptible to loss of RF telemetry after receiving a firmware update, and this has since been mitigated with a software patch. For Medtronic programmers, the initial mitigation responses of cybersecurity advisory was to take the programmers off the network. The network connection was enhanced with one or more security protections provided to the programmers using a flash drive, so the programmers can now be secured from potential cyber intrusion when connected to the network. Medtronic ICDs are currently being upgraded. The upgrade is being provided to impacted patients automatically when the device is interrogated with the programmer during follow-up. Metronic is introducing upgrades in phased approach with all expected to be completed by the beginning of 2021. There are 9% or 55,000 ICDs under this advisory that cannot receive the update due to design or safety constraints. Since the 2017 Abbott advisories identify cybersecurity vulnerabilities in pacemakers and ICDs with the potential for exploits have been increased, including 2 additional FDA advisories issued for another manufacturer. Medtronic's connected communication product and implantable defibrillators in the past 12 months. The authors comment that a recent report and a smaller number of Abbott impacted pacemaker and ICD patients from Canada reported marked differences in mitigation adoption rates between pacemakers and ICDs. This was due to an increase incremental clinical familiarity and comfort with performing the updates as experience and education surrounding these issues evolve. The authors indicate that automating cybersecurity updates without process in place for determining safety, for alerting patients or clinicians that have been delivered, may also be associated with yet unknown risks. Newer generation devices and communication protocols may render cyber security, advisories less frequent as cybersecurity integration is considered an essential aspect of device design. Paul J. Wang: In a review article, Albert Feeny and associates discuss the use of artificial intelligence [AI] and machine learning [ML] in medicine, which are currently areas of intense exploration showing potential to automate human tasks or even perform tasks beyond human capabilities. The first objective of this review is to provide the novice reader with a literacy of AI/ML methods, and to provide a foundation of how one may conduct an ML study. The review provides a technical overview of some of the most commonly used terms, challenges in AI/ML studies with reference to recent studies in cardiac electrophysiology to illustrate key points. The second objective of this review is to use examples from the recent literature to discuss how AI and ML are changing clinical practice and research in cardiac electrophysiology with emphasis on disease detection and diagnosis, prediction, and patient outcomes and novel characterization of disease. The final objective is to highlight important considerations and challenges for appropriate variation, adoption, and deployment of AI technologies and practice. Paul J. Wang: That's it for this month! We hope that you will find the journal to be the go-to place for everyone interested in the field! See you next time! This program is copyright American Heart Association 2020. Thank you.
Dec. 14th, 2020 – In this episode, the ladies sit down together after taking the Enneagram personality test! They’ve heard everyone talking about this lately and wanted to check it out. Oddly enough, they both shared the same score after completing the test. This surprised them at first but then discover that it may be the underlining connection that makes them such great friends! They discuss each of the Enneagram types (1-9) – what they are and the characteristics of each. They then take it a set further and talk about how you can incorporate these traits into improving your parenting! Suggesting some ideas, discussing pitfalls and what to look out for for each personality type. They chat about how each of these traits are essential in a thriving community and that there is no “bad” type. The women close out the show with their regular hits and misses. Sarah shares her hit based around their new puppy while Lauren deals with a miss during recording! (An important present was delivered with a revealing shipping box, and the kids got the delivery. Oh no!) Thanks so much for tuning in and if you enjoy the Mom Voice, please consider leaving a rating and review. Follow the girls on Instagram or Tik Tok @themomvoicepodcast or find them at www.mom-voice.com. New episodes released every Monday – so make sure to SUBSCRIBE! xo
One of our female tribe members from the UMS Online Coaching group recently asked if we would consider creating a supplementary course for women to get stronger in the upper body. Suggesting guys naturally have more strength, and that a specialised female strength program would be of benefit. This poses a great question … should women train differently to men? Do they need to? P.S. Whenever you're ready, here are the three best ways to work with us: 1. Join the Movement Mastermind Facebook Group It's FREE to join and we live stream our SOM podcasts to so you can interact. Today we discuss how to build better programs by revealing if women should train different to men. 2. Join Our Flagship UMS Online Coaching Program The only program that develops a true balance of strength, flexibility and fitness to unleash your inner athlete and transform your body. 3. 12-Day Of Christmas Super Sale Starts In 2 Days The 12-days of Christmas Sale launches on Saturday 12th, December. Join our online coaching program in 2020 and get every additional Masterclass FREE! --- Send in a voice message: https://anchor.fm/soundofmovement/message
A quick chat about the COVID-19 vaccine, A mall Santa got fired, Howard Stern just signed a massive new deal, Suggesting a threesome to your partner, Grandma accidentally sent nudes, Krispy Kreme will be selling boxes of donuts for $1 on Saturday, An update on the college admissions scandal, Using emojis in work emails. See omnystudio.com/listener for privacy information.
Suggesting new traditions as well as alternatives should you not be able to do the old ones!
Today I’m speaking with Dr. Michael Shermer. Michael has been on the Joe Rogan podcast multiple times, is the Founding Publisher of Skeptic magazine, the host of the Science Salon Podcast, and a Presidential Fellow at Chapman University where he teaches Skepticism 101. For 18 years he was a monthly columnist for Scientific American. He is also a New York Times best-selling author of such books as Why People Believe Weird Things and The Believing Brain.I invited Michael on because I wanted to hear from a professional skeptic how to think critically so we get closer to the truth, which is what this entire podcast is all about. In this interview he shared techniques to avoid our brain tricking us into believing things that aren’t true, what Michael believes that many skeptics don’t, his take on UFO’s in light of government released video footage, how to improve our personality traits, how in the world birds could evolve wings, and much more....I’d love to hear from you. Let me know what you like about the podcast, what you don’t, ideas for future guests, etc:Email: truthjunkiepodcastwithkevin@gmail.comFacebook: https://www.facebook.com/truthjunkiepodcastYoutube: https://www.youtube.com/channel/UCIma3aXx3l6UfjvTNM2Bg2A...Links to resources Michael mentioned:Not Born Yesterday by Hugo MercierRapoport’s Rules of Debate (Wiki) Intelligence Squared Debates: Unf*ckology by Amy Alkon Discipline Equals Freedom by Jocko WillinkThe Language Of God by Francis CollinsThe Parasitic Mind by Gad SaadContents[4:14]- Michael shares techniques to avoid our brain tricking us into believing things that aren't true.[9:52]- Suggesting real high-level, civilized debate platforms.[15:28]- Bill Eddy and his book "Why we elect sociopaths and narcissists".[24:39]- Sharing current views about UFO's[31:08]-Explaining capitalism and how poverty can be minimized in the world.[39:36]-Sharing personal experiences with UFO's/Alien abductions[44:49]-Bringing an end to psychosis, depression, suicide, violence, conflict, and war.[50:58]-Motivation should be given to the people who are feeling low in their life[57:28]- Discussing ancient hominid
“If what they’re telling you is they want to do a Bretton Woods, where we can all agree to stabilise our currencies and do massive printing… christ, if you’re after a better case for Bitcoin, I’ve never heard of one.”— Raoul PalLocation: SquadcastDate: Thursday 29th OctoberCompany: Real VisionRole: Co-Founder & CEOThe Bretton Woods agreement was created in 1944, following the end of the Second World War. The agreement pegged the US Dollar to gold, with other nations pegging their currencies to the dollar. The agreement was an attempt to stabilise economies after the devastation of the war.The IMF recently released an article in which they called the economic impact of the COVID-19 pandemic a “new Bretton Woods moment.” Suggesting that the pandemic’s effect on the economy and the substantial fiscal stimulus required may be too hard to come back from without change.The IMF announcement happened in the shadow of central banks around the world looking more and more at issuing their digital currencies. These Central Bank Digital Currencies, known as CBDCs, will give more power to the state over the control and flow of money. While this control does offer some benefits, they do also increase surveillance and reduce monetary freedoms.Are we in the midst of a revolution in money? And what does it mean for Bitcoin?In this interview, I am joined by Raoul Pal, macroeconomist and co-founder & CEO of Real Vision. We discuss the IMF considering a new Bretton Woods type system, central banks issuing digital currencies and what this means for Bitcoin.This episode’s sponsors:Kraken - The best place to buy, sell & trade BitcoinBlockFi - The future of Bitcoin financial services Sportsbet.io - Online sportsbook & casino that accepts BitcoinCasa - The leading provider of Bitcoin multisig key security.Least Authority - Helping projects improve their security and build secure technology.-----WBD275 - Show Notes-----If you enjoy The What Bitcoin Did Podcast you can help support the show by doing the following:Become a Patron and get access to shows early or help contributeMake a tip:Bitcoin: 3FiC6w7eb3dkcaNHMAnj39ANTAkv8Ufi2SQR Codes: BitcoinIf you do send a tip then please email me so that I can say thank youSubscribe on iTunes | Spotify | Stitcher | SoundCloud | YouTube | Deezer | TuneIn | RSS FeedLeave a review on iTunesShare the show and episodes with your friends and familySubscribe to the newsletter on my websiteFollow me on Twitter Personal | Twitter Podcast | Instagram | Medium | YouTubeIf you are interested in sponsoring the show, you can read more about that here or please feel free to drop me an email to discuss options.
After a long time, the Indian economy had a run of good news. Suggesting things are on the mend. But it begs the obvious question: Does one swallow make a summer or is this indeed an inflexion point for the Indian economy?
When looking for love, are you setting yourself up for failure? You’ve heard the saying, finding your “other half” completes you. Suggesting that if you’re single, there’s something wrong with you. What if you find someone you like? In today’s hook-up culture, there’s a lot of pressure to sleep with someone and if you like that person, it can ruin your chances of creating a relationship with them. How many girls have hooked up with a guy only to be disappointed when he doesn’t text or call. Exploring sexuality in our modern-day and age is challenging in all sorts of new ways. In this interesting conversation, Robin’s guest, Dr. Nancy Lee shares how to navigate the challenges of dating, how to lay the foundation for a healthy relationship, how to recognize when you are being disrespected and what to do about it, and how parents can help their teens avoid some of the bad habits we tend to pick up around dating, relationships and sex when we first start exploring our sexuality.
the thing about RCT is they are random and everything is equal. its why in table one of an RCT you should never see a pvalue because they are random and should be equal but in observational studies you see pvalues because it is not equal, it can’t be, its not random. In observational studies you try to account for all the confounders but you just cant ever make it equal to an RCT but lets look a look at observational data using a real world example. I will start with a question—is there an association between fluoroquinolone use and aortic aneurysm and aortic dissection (AA/AD).? You might say well in dec 2018 the FDA issued a warning recommending avoiding fluoroquinolone use in patients with AA/AD or who are at risk for these conditions But that was not the question I asked – I said “is there an association between c use and aortic aneurysm and aortic dissection (AA/AD).?” The answer is ‘it depends’—clearly seen in recent issue of JAMA Internal Medicine one paper – we willl call study number 1 titled “Association of Infections and Use of Fluoroquinolones With the Risk of Aortic Aneurysm or Aortic Dissection” found “Fluoroquinolones were not associated with an increased AA/AD risk when compared with combined amoxicillin-clavulanate or combined ampicillin-sulbactam (OR, 1.01; 95% CI, 0.82-1.24) or with extended-spectrum cephalosporins (OR, 0.88; 95% CI, 0.70-1.11) among patients with indicated infections” And another study in the same journal we will call study number 2 titled “Association of Fluoroquinolones With the Risk of Aortic Aneurysm or Aortic Dissection” found a small, risk for AA/AD when comparing fluoroquinolones with azithromycin for pneumonia, but no association when comparing fluoroquinolones with TMP/sulfa for urinary tract infection. AHHH SO WHAT DOES THIS ALL MEAN you ask!!!!! Well in the second study when they did a secondary analysis and limited the analysis to patients who had imaging studies the risk of AA/AD disappeared. Suggesting there was surveillance bias. Surveillance bias refers to the idea that “the more you look, the more you find.” When you get more test you find more things. For example hospital number 1 uses 1000 covid test a day and hospital two uses 1 covid test a day. Both hospitals see the same number of patients. Can you say that hospital one has more cases of covid?? Of course not, they just have a surviellance bias.. Similarly Also sicker patients who happen to get a flouroquinolone are also more likely to get a CT of their abd/pelvis which reveals aortic disease. An incidental findings that only comes about when you are sick and also happen to be placed on antibiotics. But lets go back to study number 1- the one that found no increaes risk of aortic disease when comparing flouroquinelones to other antibiotics—likely it is because they included only patients with what they termed indicated infections. This would suggest that likely it is not the antibiotic causing the AA/AD it is the illness! It is the confounders that cant be accounted for in any oberservational data set, AA/AD are not more common with flouroquinolones but unfortuneately sicker patients are both more likely to be prescribed fluoroquinolones and severe illness just also happens to be a risk for AA/AD So I ask you again, “is there an association between fluoroquinolone use and aortic aneurysm and aortic dissection (AA/AD).?” The full answer is it depends on the secenaro, it depeds on the bias, it depends on the cofounders. It just depends https://jamanetwork.com/journals/jamadermatology/fullarticle/2769109 Advisory Committee on Immunization Practices (ACIP) has issued an update on recommendations regarding HPV vaccination. Approx.. 33700 HPV caused cancers annually in the US One big problem with the data is only 8% of the studied participants are male—we basically are doing this in female and then translating the information to men which is not always the best, for example statins do not work in women to prevent heart attacks when you look at some group analysis, they help prevent strokes but not heart attacks, the numbers don’t always translate when you are crossing the gender barrier Few important points to this new update Catch-up vaccination is now recommended for all persons through age 26 years. Did get it as a kid, you can get it now, call me mustard cause when it comes to vaccines it is time to katchup ACIP recommends routine vaccination at age 11 or 12 years (or as early as age 9 years) for all persons.— regardless of prior or current HPV infection status.!!! ACIP continues to recommend age-based dosing schedules, with 2 doses for persons beginning HPV vaccination at ages 9 through 14 years and 3 doses for persons beginning after age 14 years or persons who are immunocompromised. https://www.acpjournals.org/doi/10.7326/M20-4298 what if I told you that intensive blood pressure control is not associated with incrase risk of orthostatic hypotension Effects of Intensive Blood Pressure Treatment on Orthostatic Hypotension A Systematic Review and Individual Participant–based Meta-analysis Annals of internal medicine Researchers examined five trials, with a total of 18466 participants and 127,000 follow up visits to examine the effects of intensive BP-lowering treatment on OH in hypertensive adults. As with all meta analysis the inclusion criteria of the studies did differ on what they call intensive therapy. But in the end intensive bp treatment lowered yes it actually LOWERed the risk for OH (OR .93 with 95% CI 0.86-0.99) I read this and I though no way does Intensive BP-lowering treatment decreases risk for OH. And the authors say ‘well long term or chronic hypertension can throw off many of your regulatory mechanisms, and so there for you throw off these mechanism with poor blood pressure and that is what causes the OH not the actual lower number, it is the uncontrolled bp’ and maybe they are right, that is for the ivory towers to decide I could not wrap my mind around this but then I stumbled upon it—OH does NOT mean falls. OH does not mean syncopal episodes. In this study OH only means a decrease of 20 mm Hg or more in systolic BP or 10 mm Hg or more in diastolic BP after changing position from seated to standing. This is again a surrogate marker- I don’t care if you number changes briefly if you feel fine The paper even says that the Data on falls and syncope was not available. The patient oriented outcome I care about was not available!! This is a headline paper that likely doesn’t say what you think that it says. THIS IS A LAB VALUE that grabs the headline and makes you think well intensive control actually leads to less falls or less syncopal episodes when in actually this paper just say intensive control just mean less changing of a bp number! WHICH makes sense— if you start at a lower number you have a lot less ability to change! Think about this for one second --One person in intensive control has a bp of 120 and they stand to a bp of 110 while the other person in the not intensive control arm has a bp of 130 and they stand up and the bp falls to 110--- both of those people standing have a bp of 110, the exact same bp!!!!! but one droped 20 points and is diagnosed with OH and the other is told they are normal. This next article falls into the quickest summary I have every given on a paper and it is in The Lancet Rheumatology. Titled How How long does a shoulder replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 10 years of follow-up ---which comes from the same authors that last year gave us How long does a hip replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(20)30226-5/fulltext And the famous How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up Now use their same massive database to try and answer the question how long does a shoulder replacement last and the answer is at least 10 years for most everyone. It didn’t matter if you were having humeral hemiarthroplasties, osteoarthritis with reverse total shoulder replacement, or a rotator cuff arthropathy with reverse total shoulder replacement it appears at 10 yrs approximately 90% of shoulder replacements were doing well with sustained clinical benefit. If your patients needs a new shoulder—tell them the good news is it will likely last at least 10 yrs And that was a fast summary but lets do one more--- https://jamanetwork.com/journals/jama/fullarticle/2769724?guestAccessKey=75076244-d788-4a4f-ba64-2eee4284fd70&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=etoc&utm_term=082520 Effect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D LevelsThe VDKA Randomized Clinical Trial 192 children with persistent asthma and low vitamin D level ----if you gave them vit d did you improve the time to next severe asthma exacerbation , In this randomized double-blind, clinical trial were put on either placebo or vitamin D3, 4000 IU/d The most simple answer is…..no. there was no difference between placebo and vit d
Whether the bedroom or the boardroom do you hold true to your “no” when the pressure is on?1.05- What's Kat got cooking? That moment when a friend calls and you think everything's okay and then, blah-Cartwheels out of her mouth. Cranky, life doesn't fit. Couldn't put her finger on it. Everything felt uncomfortable.2.07- frustration around trying to create boundaries to take care of self. Boundaries within herself, not with someone else. 3.08- had a hard time holding her boundaries with a friend and then she just caved. How do you respond? Say okay? Bring it up in the moment, “did you NOT hear me say NO?”4.14- oh tricky spot of people please /sacrificing. Kat was on the edge. The edge was when the person came back, even though she said no, and disregarded her no.5.26- what if it was Man who doesn't deserve a name? Rico Suave? Kris said no to both of them and yet they still reach out every couple months. Such a NO, don't bother. Old Krista would have ppl please- indulge conversation, be nice. Is the universe testing her? Still keeps saying.6.53- Alison Armstrong- sometimes have to up the pressure you bring. Nothing to do with anyone else. Is my NO really solid. Universe saying, are you really going to take care of yourself? No prob saying no to something/someone she doesn't want to engage in.8.01- How clear is your NO? Women get steamrolled over in the sweetness of saying No. How to turn that into a stronger, more powerful No. so that person gets it.8.26 not coming off forceful or like an angry bitch. Can you stand in your power?9.22- aa. Stand in the center of ourselves and come from a place with a deeper sense of self-commitment, that's the pressure.If the boundary was strong enough, Pressure wouldn't push on us. More of a soft boundary.10.11- wobble in our NO, then it turns to maybe Yes.10.36- moment you can feel when the energy changes inside of you.11.16- not talking about sex, though we know at one point or another we've all said no in the bedroom and didn't mean it.11.30 Landmark- whatever you do in one part of your life is what you do everywhere. Looking at it through the lens of self-empowerment through our No.11.57- felt like a doormat all week. Gave her no away, a power leakage.12.33- people don't actually hear you're serious the first time because they're self-serving. But if your boundary is really solid, it goes back as an echo. When we're smooshy and permeable, it doesn't have the force to receive it as a clear no. Receive it as a maybe and still get their way.14.16- Should I sacrifice myself for THIS? Are you saying no to things that you're not serious about? When you cave, you're telling yourself that your needs are less important than other people in your life.15.29- Why is that? Especially if it shows up in many areas of your life? 16.12- what is it underneath? Why is this happening? Somewhere inside of her telling her the story that she doesn't need to take care of herself as much as she's trying to take care of someone else.17.07-bottom line- devaluing our own self/needs/wants. Become perpetrator to self.17.53- not going back into regret, what could Kat have done differently? Perplexed.18.38- in theory, No means No but in reality sometimes you need to explain why.19.47- Kat had 5 situations- moment of choice when she says No, she wobbles.20.18- willing to let her need to do a good job for clients for not being solid in her No.21.17- consequence is her whole life shuts down. Way we tell ourselves these things really matters.22.34- Then there's the person trying to get their yes, what can you do to heal the pattern? Where did you push someone to get your way and say yes? Where am I doing this in my own life23.38- ooh tell me more. Kat realized she was manipulating herself. Invalidated her no, convinced herself why she didn't need the boundary. No one can do it to you without your permission.25.03- when we do this to other people, we lose as well. Do this in relationship negotiations so everyone gets needs met.26.11- Women are wired to please, instinctually for survival. But when you're trying to live into a divine life, you can't continue to give yourself up to people who have an agenda. Leaves you with a life of lack.27.24- Kat went back to “fix” and take her power back.27.58- don't worry, you can martyr me. Started with some loss of confidence within her.Katie Hendricks- will often say, what happened just before? Where did you take a little self-esteem hit?29.33- in any new relationship, always pushing up against someone's edges. Minute you say yes when you mean no, other person notices when they can get their way. It snowballs from there. 1. You're gonna lose the partnership one way or another. 2. Lose yourself, stay in position, building a lifetime of martyrdom with someone who knows they can get their way.Until you speak your truth and walk out one day.30.49- is relationship/job worth it when they take advantage of you or you allowed them to take advantage>31.42- most humbling part of it all is realization that she did it to herself. 31.58 Gave up everything even though it wouldn't work for her.32.17- you have a moment to go back and course-correct. Don't be afraid to go and undo the situation or feel hopeless. Suck it up to learning lessons.33.06- won't be resentful but grateful for the lesson to learn to not do it again.33.45- when you hold for yourself, the next opportunity meets you where you are. Get confused in the indecision- supposed to happen to me or that's my healing (happens often in the spiritual realm). Surrender to spirit's plan. Happened five times! Moved from personal to business situations. Little hiccups when stakes are low and outcomes are manageable. AS opposed to what would happen in the business situation with financial repercussions.35.08- Message of spirit: Every single one of us is as valuable as the other. Non-negotiable.36.47- Suggesting that you are clear on what you need first. Was your No heard? How many times did you have to say it before it's heard? How good is your No skill?37.08- Are you the Wall or are you Permeable? Doesn't have to be a mean wall. Season for everything. Time for discussion. Time for permeability. 37.44- what are you bargaining yourself away for? Tune into the nuances of the no. why would you give up your No, once you've said no? You know better when you know better. Holding the line to hold the line or to prove a point but could maybe switch things38.16- pay attention to when you say no, mean no, and still give it up.Inviting you to have a stronger, clearer, more depth in your NO.When it comes from a loving place, no resentment, sliding into yes later.38.38- In saying a nice clear no, you're getting better at spreading your love.www.kristakimcoaching.comwww.katherinemclelland.comSubscribe to our podcast at www.twogalssoulschool.comFollow us on IG at @twogalssoulschoolSpread the love.
Wingnut Social: The Interior Design Business and Marketing Podcast
Did you know that you CAN get to the end of your Instagram feed? Darla and Natalie have never scrolled to the end of their 48-hour Insta-recaps, but if you do, something new awaits: suggested posts. This new phenomenon replaces the notice that you’d normally get that says “You’re all caught up!” So why did Instagram give their feed an update? How does it impact YOU? Find out in this week’s Wingnut Social Monday Marketing Minisode. What You’ll Hear On This Episode of Wingnut Social [0:41] Hydrate hydrate hydrate [1:41] Instagram feed: suggested posts [3:23] The 48-hour marker [4:08] Suggesting new content [6:21] What posts will be suggested? [6:49] You cannot escape [7:32] Who will this impact? [8:42] Keep your content varied [10:58] Blooper Reel! Resources & People Mentioned TikTok Instagram Instagram’s before & after The reigning theory is that Instagram originally implemented the “end of the feed” messages to help users improve their digital well-being and limit screen time. But their newest biggest competitor—*cough* TikTok *cough*—already uses a continuous feed and it’s part of what’s made them SO successful. So Instagram is implementing this new strategy to compete. Instagram will now suggest new posts—based on what you already engage with—that will allow you to expand your horizons. They could be ads, photos, or videos—but they will NOT suggest IGTV teasers or Reels content. How Instagram’s suggested posts feed feature can impact YOU What stands out to Natalie? You cannot hide these posts. You cannot escape. But you’ll only see suggested posts if you’ve exhausted the content posted by everyone you follow. So if you follow thousands of people, you’ll likely never see the end of that yellow-brick road. However, this will impact new users with relatively small feeds. It’s a great way to increase your discoverability. This allows Instagram to increase its ad space as well. So the chances of your ad showing up in someone’s feed is pretty good. If you’re boosting a post and targeting people—here comes Darla Powell Interiors! So what content should you post? Will it positively impact analytics and increase your followers? Listen to this minisode for all the deets! Connect With Darla & Wingnut Social www.WingnutSocial.com On Facebook On Twitter: @WingnutSocial On Instagram: @WingnutSocial Darla’s Interior Design Website Check out the Wingnut Social Media Lab Facebook Group! 1-877-WINGNUT (connect with us for your social media marketing needs) Subscribe to The Wingnut Social Podcast on iTunes, Google Podcasts, or TuneIn Audio Production and Show notes byPODCAST FAST TRACKhttps://www.podcastfasttrack.com
You can be a personal trainer every client wants to work with. Though I'd argue you only want to focus on being the one your ideal clients want to work with. Now is the time to learn the skills and spend the time taking the right steps. In this episode I share 7 tips you can use right now. If you really want to be a personal trainer every woman in menopause wants you want to look at the Flipping 50 Fitness Specialist. You can be a personal trainer right now easier than ever if you're surrounded by trainers who can only offer the same service they were offering in February. This is the perfect time to make a move, grow your business, and create a deep niche. Wanting to make more money personal training and not calling customers daily is like brushing your teeth while you eat Oreos. Using social media and not doing live video is like taking a shower without using soap. Giving a woman in menopause a HIIT workout late in the day is like lighting a match in the Australian bush. Suggesting your client workout as soon as she wakes up is like insurance for physical therapists & chiropractors. Telling your menopause client to do Tabata is like telling her she is an elite male cyclist. Few clients come looking for “Pilates” with urgency. 90% of clients come looking for solutions to problems. If Pilates is your platform, speak in solutions, introduce Pilates later. That's all 7. There you have it. Seven tips to be a personal trainer every midlife woman wants. (and tells her friends about) If you want to be a personal trainer anyone wants you first want to let them see you in a way that they can see a glimpse of themselves in you. That doesn't mean that as a female in her 30s or 40s you can't work with men in their 60s or 70s. It doesn't mean as a male you can't work with young female athletes. It does mean you have to be willing to show something in you that will resonate with the clients you want. Is that thing vulnerability, drive, a chronic illness, is it a desire? Figuring out what that is, is your job. Other podcasts you might like: Like, Know, and Trust Myth #1 Fitness Marketing Mistake
Introduction Welcome to Distilling Venture Capital. I am your host, Bill Griesinger Distilling VC is a visionary podcast that provides an insightful and informed view of the key trends affecting the VC and tech startup world. My mission is to cut through and go beyond the hype that tends to dominate the tech landscape. And provide you with information you can use Opening Observations: In Today’s Episode I return to what I have termed Unicorn-mania, building on the subject of my first episode in March. So, it will be a Unicorn-mania Redux. I’m returning to this topic b/c, well, we need to revisit it primarily b/c things seem to be sliding further toward the insane, literally with each passing week. And, I will talk about the continuation of this insanity in the context of some real-life examples: The true poster-kids for “Unicorns are not real”… Specifically, I’ll provide insights into WeWork and Uber, and the unmistakable role played by Softbank’s Vision Fund in helping to fuel the craziness. And, let me say from the outset, how disappointing it is to see the technology press and the data analytics firms like CB Insights and Pitchbook (a Morningstar Co.), continue to engage in this ridiculous charade. I am going to get into some examples of that in a moment. Suffice it to say, that if you have a subscription to one of these firms, my analysis may leave you questioning what value are getting for the money… To begin, let’s quickly review what I covered and highlight a few take-aways from Episode 1 of Unicorn-mania; I outlined and highlighted the hype that characterizes VC and techland today with respect to overvalued, so-called Unicorns – companies alleged to be worth $1B+ I also highlighted the Stanford Univ. Study, Squaring Venture Capital Valuations with Reality, that reveals and proves that so-called Unicorn tech companies are substantially overvalued – and offers a valuation model that really works in valuing theses companies The Study dissects and debunks the use of post-money valuation as nothing short of an illegitimate method for valuing any company, let alone VC-backed private tech companies. Before I go further into the topic, I am going to strongly encourage you to please refer to the Show Notes for this Episode to access links to the following: Link to Stanford University Study: Squaring Venture Capital Valuations with Reality - Downloadable pdf found here: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2955455 (Social Science Research Network – SSRN) Link to Video: Presentation at SVOD (Sil. Valley Open Doors Conf.), June 2016 by Ilya Strebulav, author of the Study and Professor, Stanford Univ. Grad. School of Business: https://youtu.be/k4OtGWZ3iYI Original Version of the Study was submitted and published April 19, 2017; However, the findings were presented about a year earlier in June 2016 at SVOD Conf. (Silicon Valley Open Doors) Where Prof. Strebulav was the Keynote Speaker (I encourage you to got to the link and watch it. It’s < 20 minutes) Summary of the Findings – From the Study Abstract: We develop a valuation model for venture capital--backed companies and apply it to 135 US unicorns, that is, private tech companies with reported valuations above $1 billion. We value unicorns using financial terms from legal filings and find that reported unicorn post--money valuations average 48% above fair value, with 14 being more than 100% above. Every Company reviewed and valued, (100% of the Sample) was overvalued to some degree – that means not one company came in at the post-money valuation utilized by the VC industry Values were calculated for each share class, which yields lower valuations because most unicorns gave recent investors major protections such as initial public offering (IPO) return guarantees (15%), vetoes over down-IPOs (24%), or seniority to all other investors (30%). According to the authors, “Overvaluation arises b/c the reported valuations assume all of a company’s shares have the same price as the most recently issued shares.” Even though each new round of funding effectively sucks the value out of prior rounds through seniority and superior rights, among other preferences. Common shares lack all such protections and are 56% overvalued. After adjusting for these valuation-inflating terms of the Preferred rounds, at the time of the Study, almost one-half (65 out of 135) of unicorns lose their unicorn status. Stanford Study Pre-work: In 2016, prior to publishing the Stanford Univ. Study, Strebulav and his team of researchers surveyed, as part of their work, more than 1,000 VCs regarding valuations. It was the first survey of its kind: Result; 92% of respondents of the VCs surveyed agreed unicorns are over-valued; A whopping 75% believe unicorns are significantly over-valued AND, as I noted in Episode I, did you ever notice that the PE industry doesn’t have an equivalent designation (Unicorns) for its $1B+ value companies, even those that are in the tech category? Why this study’s findings are not a wake-up call to the industry is currently a mystery to me. Who Cares? To demonstrate that my concerns and the opinions I’ve expressed, that Unicorn-mania is a total distraction, a waste of time, as I stated in Episode I, are not just some overly-dramatic soap-box issue I am on… Turns out, I am in some pretty impressive company, actually – with respect to my criticisms of the mania. Let’s take a look: All of the examples are from the 4th Quarter of 2015, when some rather prominent and accomplished investors and tech company leaders had begun calling BS on Unicorn valuations, even before the real Mania commenced in earnest over the last several years: Marc Benioff, Chmn and CEO of Salesforce, Dec. 2015 on Bloomberg TV stated, “The unicorn mania that’s going on, that’s dangerous for our Silicon Valley economy," “this is just, you know, unheard of... It’s become a self-esteem issue for these entrepreneurs.” Benioff states to the SF Bus. Times, also Dec. 2015: “I’m not buying the unicorn theory…" There's no reason [for] these companies who claim to be worth billions of dollars and making billions of dollars to stay in the private markets." Benioff asserted that some billion-dollar valuations are the result of "manipulation" of private tech markets and again called on founders to go public to "rationalize" their worth. Suggesting, by implication, that these values are not rational! Legendary VC John Doerr, who joined Kleiner, Perkins, Caufield in 1980 – [did they even call it venture capital back then?] – In the same 12/7/2015 SF Bus. Times article Doerr pointed out, “Google has acquired one company per week since 2010 but has only five times paid more than a billion dollars for a company,” Doerr said. “There are 150 companies considered unicorns, 93 are in the United States. How does that math work?” Great Q indeed! I suggest it doesn’t, b/c it’s not about the math but rather about the hype. Bill Gurley, another highly respected and accomplished VC veteran from the Valley and Founding partner of Benchmark Capital. In Oct. 2015 at the WSJ Laguna Beach Tech Conf. stated, "All these private valuations are fake. ... It's all on paper, it's all a myth," "Anyone that's raised $400 million is probably spending $100 million a year," he said. "Until you get liquid, you haven't really accomplished anything." And finally, Mark Suster, a voice I respect a lot in the industry. He has been a Managing Partner at Upfront Ventures since 2007. Suster puts out one of the better blogs in venture called “Both Sides of The Table” in which he dispenses and provides excellent, valuable, how-to and other advice for start-up entrepreneurs on a whole range of topics – you should check it out. Well, back in a Sept. 2015 piece that he published on his blog, Mark does not hold back with his sentiments regarding Unicorns stating, “There’s no one sane I know any more who doesn’t privately say that things have gotten out of hand. Few like to say so publicly. And I blame unicorns. Mark is very clear that he’s not referring to what he identifies as “successful” companies themselves but “the entire bullshit culture of swashbuckling startups who define themselves by hitting some magical $1 billion valuation number and the financiers who back them irrespective of metrics that justify it. Unicorn has become part of our lexicon in a sickening way and will no doubt become part of the history we tell about how things got so out of control again. 10 years from now people will be embarrassed to say unicorn.” Well, we are about 5 years out from those highly critical assessments from some really smart people in the industry. Unfortunately, the sane voices of these reputable tech titans from late 2015 have gone under-reported or unreported in recent years. Which, I guess, is a primary symptom or characteristic of a “Mania” itself – delusional thinking…prone to exaggeration, denial and so on, but I’m no doctor…so I’ll leave that diagnosis for others to ascertain. I stated in Episode I in March, It Is a big distraction from what’s really important in evaluating and valuing venture-backed tech companies. We’ve been completely DISTRACTED for nearly 5 consecutive years since the warnings and criticisms of this mania in 2015 by key, reputable industry players in VC and tech. And, that’s despite the publication and dissemination of the most conclusive, comprehensive accurate study ever regarding what the valuations of these companies really are. Here’s the central problem – The $1B+ valuations ascribed to so-called unicorn companies are not true market valuations at all. They all utilize a metric called “post-money valuation” that inflates their value. As stated, the Stanford Univ. Study found 100% of all unicorns are actually over-valued to some degree when applying proper market valuation metrics based upon the terms and conditions found in the Preferred Stock rounds The Post-money valuation methodology is like an alternative universe, or worse, when it comes to valuing private tech companies. This should not be the case. The multitude of preferences, IPO kickers, and other terms and conditions attached to these preferred rounds have no relationship to company fundamentals and performance. Again, I understand why many are being negotiated…b/c of the high risk and probability of failure in the VC model. So what Strebulav and Gornall had to do in building their model was to be able to identify and value all of the disparate Ts & Cs underlying all the different Preferred rounds, each with differing economics, rights and conditions by round. This was a rigorous and complicated undertaking. They have done the industry a great service the development of this model. One of The Study’s major conclusions: “Our results show that equating post-money valuations and fair values is inappropriate.” AND, “Marking unicorns to their most recent round’s price leads some venture capitalists to overstate their funds unrealized value. Unrealized asset values are an important determinant of future fund-raising.” Most LPs revealed to the Study’s authors that most VC funds mark all of their investments to the most recent round’s price. It might be understandable why an unsuspecting public might not get the full risk impact of this, one wonders why major, sophisticated LPs put up with this nonsense… Mutual Fund filings show that almost all of the major mutual funds tend to hold their private VC-backed assets at the post-money valuation. Where are the Real Journalists? On the Media side - There exists an almost a schizophrenic-like behavior exhibited by the technology press in its years-long coverage of unicorns; To be sure, at the beginning there were some real attempts by a handful of outlets to highlight the findings of the Stanford Study, which were astounding; e.g. - CB Insights CEO, Anand Sanwal, opined in an August 2019 piece that it (unicorn status) is often used as a scheme to attract top talent in a very tight hiring market for key tech talent… PitchBook Weekend Pitch from Nov. 3, 2019: “For a long while in and around Silicon Valley, unprofitability was what every startup hoped to achieve. And if losing hundreds of millions of VC dollars was cool, then Adam Neumann was Miles Davis.” Really? Are you kidding me? This is your expert analysis that PitchBook is charging for? PitchBook continues, “But these days, in the wake of WeWork’s sudden fall from grace, investors are feeling differently. All those years of red ink are finally adding up.” The only redeeming thing I could take from such a ridiculous statement is that the writer even knows who Miles Davis is. But then I realize, the whole thing is an insult to Miles Davis and our intelligence. Miles Davis was a musical/jazz genius, a master artist. Adam Neumann was a fraud. And the VCs in the WeWork deal should have known this through their diligence. So, my criticism is reserved for the adults that allow this nonsense to continue, followed closely by some of the more youthful folks who are in senior roles at the data analytics companies (CB Insights, PitchBook) and write the articles for TechCrunch, Wired, Crunchbase, et. al. Whether you realize it or not, you are on a path to making yourselves irrelevant, in my opinion. Your so-called analysis is not widely recognized as providing rigorous, meaningful, and dependable insights and analytics regarding what’s really going on in tech. It’s more like click-bait tactics to get noticed and get “likes” than demonstrating some actual skill and expertise as to how firms should be evaluated and valued by those making the investment or managerial decisions…What are your subscribers actually paying for anyway? Further, as stated in Episode 1, It’s a Consumer Protection Issue: Definitely NOT a soap box issue! A number of the largest US mutual fund companies (Fidelity, JH, T. Rowe Price and Vanguard) have invested directly in private co. unicorns In 2015, Fidelity > $1.3B into unicorns! That’s more than any single US-based VC fund invested, in total, that year. Including $235M in WeWork, $129M in Zenefits – A company that hired too many people, grew too fast, and the company culture spiraled out of control, and $118M in Blue Apron, the food delivery startup that IPO’d in June 2017 and is now looking for a buyer… The common thread on all these investments by major mutual fund companies? Use of the meaningless post-money valuation to value these private tech company assets in their portfolios. It’s Mind-boggling to think that this is the valuation methodology used… Incredibly, they have accepted and used these meaningless valuations to mark their holdings of these private tech companies w/o further analysis – a completely irresponsible methodology. It surely doesn’t inspire confidence in their ability to perform proper valuation analytics Where’s the adherence to the fiduciary responsibility of these investment firms to their clients? There are real financial implications for any retail investor in a mutual fund (401k or directly) related to this high-risk category. How about institutions? Univ. endowments, public pension funds, etc.? Are mutual fund companies fully disclosing real risk of this asset class to their retail investors? Accurately? How so, if at all? (e.g. – Fidelity had to recently write down its WeWork holdings to reflect the difficulties the company has “reported” after the cancelation of its IPO.) Where are the Regulators? The SEC… Sagas of WeWork and Uber They represent some of the many Poster-Kids for, Unicorns aren’t real I want to take a look at Uber first then we’ll talk about WeWork. Uber went public in May of 2019, so a little over a year ago. It priced its shares at $45 upon IPO The IPO was billed as the largest of 2019 as Uber sought to go out at greater than $100B with $120B even suggested by some of the I-Banks underwriting the deal. However, what’s intriguing is to evaluate, are the Uber valuations in the years leading up to its IPO – In fact, Strebulav Stanford Study authors, posted to Linkedin in early 2018 that they extended their analysis to re-value Uber after a deal it closed at the time with SoftBank – we are in Jan. of 2018, more than a year before Uber’s IPO. Basically, a consortium led by SoftBank and prior investors, they were purchasing about $8B worth of Uber Common and some early preferred shares in a tender offer for about $34/share AND; An additional $1.25B consideration for some Series G-1 shares for $49/share. Based on the deal terms and details analyzed, it was determined that the Series G-1 shares I just mentioned, being purchased at $49/share, had no special features or terms making them worth more than Common shares. So, why the 42% mark-up as part of this transaction? Conclusion: My Recommendation/proposal: All private tech company valuations should be run through the Stanford Univ. Study Model prior to any kind of exit or any time the value of a private tech company needs to be certified for audit or other purposes. These companies owe it to their employees who are provided, in many cases, with near worthless Common stock or options for common. In the interest of time and also to provide a proper analysis, I prefer to save WeWork’s story and saga for my next Episode. Thank you for joining me for this edition of DVC. I hope you found the topic interesting and useful. I am currently working on the DVC website. In the meantime, Please send questions and your comments regarding today’s episode to: bill@ccs.capital Stay tuned for my next Episode, in a few days, where I will pick back up with discussing and analyzing WeWork’s saga, … Thank you for joining me for this episode of DVC…
The Modern Therapist's Survival Guide with Curt Widhalm and Katie Vernoy
Is Therapy an Opiate of the Masses? Curt and Katie chat about how therapy can collude with the status quo and has historically failed to serve marginalized populations. We talk about the risks of therapy that doesn’t honor the context and systems within which people and families operate. We look at how therapists can create complacence and obedience if not careful. It’s time to reimagine therapy and what it means to be a therapist. To support you as a whole person and a therapist, your hosts, Curt Widhalm and Katie Vernoy talk about how to approach the role of therapist in the modern age. In this episode we talk about: Criticisms of therapy as an opiate of the masses Does therapy reinforce the status quo? “Normal” as a culture bound concept Feminist Therapy, Liberation Psychology, Decolonized Therapy The history of pathologizing or demonizing LGBTQ+ Therapy as a white construct Bias in MMPI and re-norming How bias toward “normal” permeates clinical work How therapists reinforce systems norms, encouraging placating the system First, Second, and Third Order change – Individual within family within the systems within which the family operates Individual versus collective change The challenge of assessing and treating within the complex overlay of systems The limitations of evidence-based treatments The vision of acceptance of diversity Therapist training gaps The Seven-Eyed Model of Supervision Impacts for case conceptualization Looking at clients as agents of change, as impacted by their context Validating experiences, increasing resilience and capacity, empowering client to make larger changes Suggesting coping skills without diminishing systemic impacts Therapy as a bandaid “As therapists, we can do a really good job of moving people to complacence if we’re not careful.” – Katie Helping individuals to heal, then moving to “now that” The requirement for therapists to be advocates for change within their communities Our Generous Sponsor: Brighter Vision Hey Modern Therapists! Do you need help building your brand? Feel like you don’t even know where to begin when it comes to marketing your practice online? Whether you’re a seasoned clinician with a website in need of a refresh, or you’re fresh out of school needing your very first therapist website, Brighter Vision is the perfect solution. From building a brand and designing the perfect website to reflect that, to helping you rank higher with search engines. They’ve even created tools to make online marketing simple that are specifically for therapists. We’ve worked with them to create a special offer just for all of you Modern Therapists. All you have to do is go to brightervision.com/modern to learn more and get your first month free of any new website package. Resources mentioned: We’ve pulled together resources mentioned in this episode and put together some handy-dandy links. Please note that some of the links below might be affiliate links, so if you purchase after clicking below, we may get a little bit of cash in our pockets. We thank you in advance! The Prostitution of Psychotherapy: A Feminist Critique Third-Order Thinking in Family Therapy: Addressing Social Justice Across Family Therapy Practice Seven-Eyed Model of Supervision Decolonizing Therapy on Instagram Prevention of farmer suicides: Greater need for state role than for a mental health professional's role Therapy Reimagined 2020: Therapy Reimagined 2020 Conference Therapy Reimagined 2020 Call for Sponsors Relevant Episodes: Therapy as a Political Act Is CBT Crap? Defining the Therapy Movement Interview with Dr. Harry Aponte: The Person of the Therapist Interview with Dr. Joel Schwarz: Neurodivergence Interview with Dr. Jamie Marich: Exploring Trauma and the 12 Steps Connect with us! Our Facebook Group – The Modern Therapists Group Get Notified About Therapy Reimagined 2020 (and TR2019 Virtual Conference) Our consultation services: The Fifty-Minute Hour Who we are: Curt Widhalm is in private practice in the Los Angeles area. He is the cofounder of the Therapy Reimagined conference, the CFO of the California Association of Marriage and Family Therapists, an Adjunct Professor at Pepperdine University, a former Subject Matter Expert for the California Board of Behavioral Sciences, and a loving husband and father. He is 1/2 great person, 1/2 provocateur, and 1/2 geek, in that order. He dabbles in the dark art of making "dad jokes" and usually has a half-empty cup of coffee somewhere nearby. Learn more at: www.curtwidhalm.com Katie Vernoy is a Licensed Marriage and Family Therapist, coach, and consultant supporting leaders, visionaries, executives, and helping professionals to create sustainable careers. Katie, with Curt, has developed workshops and a conference, Therapy Reimagined, to support therapists navigating through the modern challenges of this profession. Katie is also President of the California Association of Marriage and Family Therapists. In her spare time, Katie is secretly siphoning off Curt's youthful energy, so that she can take over the world. Learn more at: www.katievernoy.com A Quick Note: Our opinions are our own. We are only speaking for ourselves – except when we speak for each other, or over each other. We’re working on it. Our guests are also only speaking for themselves and have their own opinions. We aren’t trying to take their voice, and no one speaks for us either. Mostly because they don’t want to, but hey. Stay in Touch: www.mtsgpodcast.com www.therapyreimagined.com Our Facebook Group – The Modern Therapist’s Group https://www.facebook.com/therapyreimagined/ https://twitter.com/therapymovement https://www.instagram.com/therapyreimagined/ Credits: Voice Over by DW McCann https://www.facebook.com/McCannDW/ Music by Crystal Grooms Mangano http://www.crystalmangano.com/
In this chapter Moses recounts Israel's history of disobedience. It is a reminder to them before they cross the river Jordan that the reason they wandered forty years in the wilderness was because they failed to trust in the Lord. Suggesting they better not repeat their mistake this time.
Staff are arguably the most expensive “line item” on most companies’ budget sheet. Yet, the lion’s share of effort, resource and creativity is spent on our customers, and far less is given towards creating a truly effective employee experience. That’s what today’s podcast episode is all about, as David and Mark question why we aren’t more focused on our biggest asset. From why “HR” is often tactical, reactive and responsive and not considered at a Leadership level, to why top-down announcements in real-time aren’t the only way to share information. Suggesting that companies who apply the same approach that revolutionised customer success in recent years, to changing employee engagement, could be the ones who win. --- Show notes: Find out about ScreenCloud: screencloud.com Connect with David Hart or Mark McDermott on LinkedIn. Get in touch: hello@screencloud.com
Riot Talk Live :: Some people want to see cops get shot, some people are aghast :: Suggesting stateless solutions, again :: James from AZ threatens Mark :: Lots of callers :: David talks about how he knows all about this stuff :: Mark, Melanie and Richie Rich
Veterans in the United States take their own lives at an alarming rate. Suggesting new ways to prioritize mental health in the military, veterans advocate Charles P. Smith offers a data-driven plan to help prevent suicide and ensure service members get proper care before, during and after active duty.
Veterans in the United States take their own lives at an alarming rate. Suggesting new ways to prioritize mental health in the military, veterans advocate Charles P. Smith offers a data-driven plan to help prevent suicide and ensure service members get proper care before, during and after active duty.
Veterans in the United States take their own lives at an alarming rate. Suggesting new ways to prioritize mental health in the military, veterans advocate Charles P. Smith offers a data-driven plan to help prevent suicide and ensure service members get proper care before, during and after active duty.
Veterans in the United States take their own lives at an alarming rate. Suggesting new ways to prioritize mental health in the military, veterans advocate Charles P. Smith offers a data-driven plan to help prevent suicide and ensure service members get proper care before, during and after active duty.
Fat Hen is a short and chubby Habano with a combination of premium tobacco leaves from Ecuador, Nicaragua, and the Dominican. This version is the 2nd vitola in the line and much bigger. They have prominent notes of earth, spice, and woodiness. A very nice cigar we both liked a lot. It’s very smooth with excellent construction. This is one of the any time of the day cigars they are talking about. With this we have Ron Zacapa. From Guatemala, this smooth aroma honeyed, caramel, and fruity rum is Bills favorite. Sweet and mouth-warming with hints of oak, vanilla, dried fruits and some liquorish. The finish is long and sweet with vanilla, coffee, smoke and honey and it has the tiniest amount of marzipan creeping up to the palate. Although the description is not his this is a medium sweet rum that has a great flavor and smoothness. They lament the neighbor’s noisy rooster and talk about the massive GDP contraction that occurred during the shelter in place. Suggesting that soon more fast food restaurants will be adding app ordering like Starbucks has. This shelter in place and shutdown has probably launched another jump in automation. They talk a little about zoom herfs and how much they want to be back to face to face conversation. They also talk about 'How to Win Friends and Influence People'. A must read.
Sponsored by Datadog: pythonbytes.fm/datadog We’re launching a YouTube Project: pythonbytes.fm/youtube Brian #1: Announcing a new Sponsorship Program for Python Packaging “The Packaging Working Group of the Python Software Foundation is launching an all-new sponsorship program to sustain and improve Python's packaging ecosystem. Funds raised through this program will go directly towards improving the tools that your company uses every day and sustaining the continued operation of the Python Package Index.” Improvements since 2017, as a result of one time grants, a contract, and a gift: relaunch PyPI in 2018 added security features in 2019 improve support for users with disabilities and multiple locales in 2019 security features in 2019, 2020 pip & dependency resolver in 2020 Let’s keep it going We use PyPI every day We need packaging to keep getting better You, and your company, can sponsor. View the prospectus, apply to sponsor, or ask questions. Individuals can also donate. Michael #2: energy-usage A Python package that measures the environmental impact of computation. Provides a function to evaluate the energy usage and related carbon emissions of another function. Emissions are calculated based on the user's location via the GeoJS API and that location's energy mix data (sources: US E.I.A and eGRID for the year 2016). Can save report to PDF, run silently, etc. Only runs on Linux Brian #3: Coding is 90% Google Searching — A Brief Note for Beginners Colin Warn Short article, mostly chosen to discuss the topic. Michael & Brian disagree, so, what’s wrong with this statement? Michael #4: Using WSL to Build a Python Development Environment on Windows Article by Chris Moffet VMs aren’t fair to Windows (or macOS or …) But you need to test on linux-y systems! Enter WSL. In 2016, Microsoft launched Windows Subsystem for Linux (WSL) which brought robust unix functionality to Windows. May 2019, Microsoft announced the release of WSL 2 which includes an updated architecture that improved many aspects of WSL - especially file system performance. Check out Chris’ article for What is WSL and why you may want to install and use it on your system? Instructions for installing WSL 2 and some helper apps to make development more streamlined. How to use this new capability to work effectively with python in a combined Windows and Linux environment. The main advantage of WSL 2 is the efficient use of system resources. Running a very minimal subset of Hyper-V features and only using minimal resources when not running. Takes about 1 second to start. The other benefit of this arrangement is that you can easily copy files between the virtual environment and your base Windows system. Get the most out of this with VS Code + Remote - WSL Python Extension Anaconda Extension Pack Brian #5: A Pythonic Guide to SOLID Design Principles Derek D Again, mostly including this as a discussion point But for reference, here’s the decoder Single Responsibility Principle Every module/class should only have one responsibility and therefore only one reason to change. Open Closed Principle Software Entities (classes, functions, modules) should be open for extension but closed to change. Liskov's Substitutability Principle If S is a subtype of T, then objects of type T may be replaced with objects of Type S. Interface Segregation Principle A client should not depend on methods it does not use. Dependency Inversion Principle High-level modules should not depend on low-level modules. They should depend on abstractions and abstractions should not depend on details, rather details should depend on abstractions. Michael #6: Types for Python HTTP APIs: An Instagram Story Let’s talk about Typed HTTP endpoints Instagram has a few (thousand!) on a single Django app We can have data access layers with type annotations, but how do these manifest in HTTP endpoints? Instagram has a cool api_view decorator to “upgrade” regular typed methods to HTTP endpoints. For data exchange, dataclasses are nice, they have types, they have type validation, they are immutable via frozen. But some code is old and crusty, so TypedDict out of mypy allows raw dict usage with validation still. OpenAPI can be used for very nice documentation generation. Comments are super interesting. Suggesting pydantic, fastapi, and more. But that all ignores the massive legacy code story. But one is helpful and suggests Schemathesis: A tool for testing your web applications built with Open API / Swagger specifications. Extras: Michael: superstring follow up Joke: "How many programmers does it take to kill a cockroach? Two: one holds, the other installs Windows on it."
In this episode, as the election draws near Chris Wallace shows Biden and Trump in a dead heat. Suggesting that going into September and October voters will make a judgement call on whether Trump handled the health crisis well. Also, Biden's potential VP pick, who's on the short list?
Suggesting ways to keep us all from going stir crazy
This is an “In between interview episode” intended to draw out the learning from the previous one. Suggesting that moralism might be what’s going on in the world today, Judy describes how something as important as a moral compass can be given the power to destroy our world. With more passion than normal, she invites us to give one another freedom to form and live our own moral values. The unconscious insistence that I am right, automatically labels everyone who doesn’t agree as wrong. A great deal of insecurity arises with the need to be certain leads to judgment and a need to control others so that what I believe is right can rule. Even though the episode is based on the judgment Danny (episode 18)received from the church for being gay, it would be a mistake to see this as an episode evaluating homosexuality. This is just one more episode that gets to the heart of what it means to be human together. This episode begs the following questions... Once we determine that all of us humans matter, will the divisiveness we feel dissolve? Are relationships possible across dividing beliefs if we matter? What do any of us have to lose by leaning in to find out? Listening to the end offers the opportunity to sign up for a group coaching course that explores the goodness of agenda-free loving. Want to dialogue more? Join our Facebook group here. Any questions or comments? Email me directly here. Ready to start transforming your relationships? Go to our website and check out the resources on my coaching page.
Episode 59 – Tactics of Influence Influencing others is a powerful tool essential for every leader to develop to be successful. Join Brian & Ed in the process of learning these tactics, it will create a healthier, more productive atmosphere of collaboration in the workplace, where everyone can win, and work is done effectively and efficiently. It’s important to remember that you don’t have to start out with a natural talent for influencing others to become effective at using these tactics. 9 Tactics for Effectively Influencing Others Logic – Convince someone by using factual, logical and step-by-step reasoning. Inspiration – Suggesting what may happen as opposed to fact-based reasoning. This appeals to emotions more than logic. Participation– Asking a number of questions where the answers will lead the other person to draw his own conclusions. Uplift– Making someone feel good about him/herself and start listening to you. Deal– Offering something in return for something. Quid pro quo (Latin) “this for that”. Favor– Asking for something you want. Collective– Using the view of other people to influence someone. Policy– Authority is effective as a quick response to a problem. It is very blunt and sometimes provocative. Force– Exercising power. Always a last resort. The article for this episode can be found at: https://fromthegreennotebook.com/2019/06/06/the-goal-of-self-development-knowledge-vs-wisdom/ You can see more about the Instinctive Influencers at: Our website Link – instinctiveinfluencers.com Our Facebook Link - https://www.facebook.com/101influence/ Our Instagram Link - https://www.instagram.com/instinctiveinfluencers/ Our Twitter Link - https://twitter.com/101Influence Be sure to Subscribe, Rate, and Review on our show on the Facebook Page and Apple Podcast. This is how we will continue to create, broaden, and amplify content for all to learn from and grow. Intro & Outro Music: Cosmic Storm by A Himitsu: https://soundcloud.com/a-himitsu Creative Commons – Attribution 3.0 Unported – CC By 3.0: http://creativecommons.org/licenses/by/3.0/ Music promoted by Audio Library: https://youtu.be/U4wXUdhNxZk
Having Purpose in Your Business with Molly Stillman In this episode we dive in to finding purpose with your business. Molly Stillman of Still Being Molly blog and Business with Purpose Podcast shares how she grew from a quiet blogger to a full time business CEO with a purpose. Molly Stillman is the founder and creator of Still Being Molly, a life and style blog started in 2007, and the host of the Business with Purpose podcast. With over 600,000 readers in the last year, stillbeingmolly.com has become a trusted community for women, especially moms, who love everything from ethical style and clean beauty, to parenting and real food, to serving in their communities and making the world a better place. Her true passion lies in helping inspire women to know that they were created on purpose, with a purpose, and for a purpose. Molly has had the honor of collaborating with well-known brands such as Stitch Fix, Target, Elegantees, The Root Collective, Sseko Designs, CAUSEBOX, Noonday Collection, and more. Molly is honored to have been featured in such publications and media as US News & World Report, Scary Mommy, Fashion Revolution’s Zine “Loved Clothes Last”, The 700 Club, North State Journal, Cary Magazine, and was named as one of “the Carolina’s 75 Most Stylish People” by Carolina STYLE Magazine. She is a wife, mama, dog mom, a loud laugher, lover of Jesus, Diet Coke and all of the Chipotle burritos. You can find her on the internets at http://www.stillbeingmolly.com Connect With Molly Here: Want to join my ethical brand directory? Suggesting a guest for the Business with Purpose Podcast? Want to join the Purchase with Purpose Facebook community? You're in the right place. http://eepurl.com/dxGGHr Facebook Link http://www.facebook.com/stillbeingmolly Instagram Name http://www.instagram.com/stillbeingmolly Did you know that success starts on the inside? I believe that to BE a successful entrepreneur and networker you have to develop the mindset for a high achiever. This means telling your inner mean girl to shut the f*ck up. This is why I have created my 5 Steps to Silencing Your Inner Mean Girl Guide. This is designed to help you step into the mindset of the high performer and start cracking your unique code for success. I want to show you how to manage that inner critic, so you can start to think, act and and get the results of the high performer. Grab my cheatsheet here: www.silenceyourmeangirl.com The best part, it is absolutely free. Just visit, www.silenceyourmenagirl.com and grab your copy today. Friend it is your time to unleash your success. About Angela: I am a certified life coach and high performance mentor to women building their dream career and life. I help them implement a step by step system to: Stop the Trash Talk in your head that is making you crazed Break through the glass ceiling you put on yourself (grab a hammer!), so you can reach the goals that always seem just out of reach. (Hello 6 figures) Manage the mean girl in your head so you can actually start hitting the big goals that just always seem out of reach. (B*tch Doesn’t Stand a Chance) Get clarity on your future, stopping the confusion on what to do next Ditch the overwhelm for harmony so you can actually enjoy the journey. Ditch the “I’m not good enough.” witchy inner critic so you can attract your soul mate clients and customers to you Find freedom from people pleasing, perfectionism and being a control freak. (Don’t just hide the crazy, be free!) Build a life you don’t need to numb your way through Drop the half-*ss habits that are sabotaging your business and establish success habits that will actually move you into high performance. Move into a high achievers mindset and start BEing a Courageous, Confident Curvy CEO of your life! Let's Connect! Grab my Silence Your Mean Girl Cheatsheet Here: www.SilenceYourMeanGirl.com IG: @angela_naumann FB: https://www.facebook.com/AngelaNaumannCoaching Free Facebook Group to Connect with other Female Entrepreneurs in the Female Entrepreneurs Connection Group Here: https://www.facebook.com/groups/463767070896919/ Web: www.angelanaumann.com Wanna Work with Me? Schedule a free 30 min. strategy session to see if you an are coaching match. https://calendly.com/angelanaumanncoaching/freecoaching If you enjoyed this episode and it inspired you in some way, I'd love to hear about it and know your biggest takeaway. Leave us a review on iTunes and then take a screenshot of you listening on your device, post it to your Instagram stories and tag me. @angela_naumann We are having a free give away of my 1 Free Membership to My Success Academy. To be entered into to the drawing, just leave a review on iTunes between now and New Years Day 2020.
Body water represents 76% of a human’s muscle mass. With aging, there is a progressive decline in total body water (TBW) – the result of sarcopenia, the aging loss of muscle, and the associated dynapenia, the aging loss of strength, without the intervention of resistance training and increased protein intake – from 0.8 grams per kilogram (Kg) to 1.2 grams per Kg in a non-athletic population. The result of sarcopenia is the loss of intracellular water (ICW).In addition, the elderly is at increased to chronic dehydration, which cannot only affect muscle function, but also functional capacity to perform everyday tasks.Researchers from Barcelona Spain writing – The Role of Water Homeostasis in Muscle Function and Frailty: A Review – in the August 2019 issue of the online, peer review journal Nutrients, comment that, “the role of water in muscular function in the aged population is poorly understood and evidence is both scarce and scattered.”Suggesting that progressive age-related dehydration may be responsible for muscle function impairment and frailty, the Spanish researchers chose to review cell dehydration mechanisms and the potential consequences for muscle function in the aged population.The investigators note that water function to act as a medium for all biochemical metabolism, a transport function, temperature control, structural, and mechanical function. In addition, water represents roughly 60% and 55% of body weight in adult males and females, and around 75% in children – with 70-75% in fat free mass and 10% in fat mass.As lean mass decreases with age, with potential for an increase in fat mass, there is a potential for TBW loss in women and obese individuals.From a dietary perspective food intake accounts for 20% of total water input – with beverages contributing 70-75%. Daily normal water loss comes from urine output, faecal and respiratory exchange (insensible perspiration).Water balance (homeostasis) is achieved via the kidneys, where hormones such as anti-diuretic hormone (ADH) controls the thirst and urine output mechanisms, among other body control mechanisms.The researchers point out that, “the aged population runs a greater risk of dehydration. Prevalence of dehydration in the elderly has been estimated at 20–30% and is associated with greater disability, morbidity and mortality.”Further, “alterations in the hydro-electrolytic balance may cause decreased muscle strength, gait instability, falls, fractures, respiratory infections, confusion, renal failure and increased medication toxicity and may increase the risk of death.”Causes of dehydration in the elderly are mainly related to a reduced thirst sensation consistent with a reduced ability to concentrate urine. Compared with younger adults, individuals aged 60–79 years old maximum urine osmolality and solute absorption are 20% and 50% lower, respectively.The researchers conclude by saying that, “water is an essential nutrient for life as it plays fundamental metabolic, transport, structural and temperature control roles in the body. Ageing is characterized by slow and progressive process of dehydration and hyperosmotic stress, which, apart from being related with inflammation, causes cell shrinkage and damage to intracellular protein structure and function.”
Summary: Delia and I explore what it's like to question our beliefs, and the pros and cons of doing so. Watch video of this talk here: https://youtu.be/T2EgJjQRsYE Location: San Antonio, Texas Recorded: 23 August 2019 Released: 18 October 2019 Twitter: https://twitter.com/magnabosco (follow me) YouTube: https://youtube.com/magnabosco210 (tons of Playlists) Facebook: https://facebook.com/magnabosco210 (like my page) Website: https://anthonymagnabosco.com (contact me, appearances) SE Resources: https://tinyurl.com/abm-se-resources SE Community: https://tinyurl.com/abm-se-community SE Discord Server: https://discord.gg/sKap3zM Skip ahead to a desired point in the talk: -- Intro (very suspense): 00:01 Explanation: 00:54, 05:09, 07:21 Rapport-Building: 01:47 Storytelling: 04:35 Repeating: 05:42, 06:12, 06:24, 08:26, 09:31, 11:10, 15:26 Justification (Why): 06:37, 07:01 Challenging: 07:57, 10:30, 12:33, 14:46, 15:14, 16:26 Valuating: 08:21, 08:57, 12:22 Wondering: 09:18, 14:06, 20:04 Agreeing: 10:02 Clarifying: 12:05, 18:43 Visualizing: 17:15, 19:17 Warning: 18:26 Questions for Me: 20:47, 22:44 Mirroring: 22:36 Re-Cap: 25:29 Outro: 27:58 -- Note: Add 5 seconds to these timestamps if listening to the podcast version of this talk. Audio correction provided by Philipp Grzemba. Outro Music 'Podcast Intro Whateva’ provided by Jim Rhodes. Music provided by Jim Rhodes, with Dan Harris on lap steel. Intro Music is 'The Awakening' provided by YouTube, from Patrick Patrikios and was not intended to be taken ("very suspense") seriously. Links to References in Video: Watch full talk w/Jackie (hummingbird): https://youtu.be/M1X2AuYJ8Xc ** Add foreign language captions w/YouTube's community contributions tools ** Mistakes: In retrospect, I think asking Delia if she wanted to be a "questioner" or "sing the songs" may have framed her options as binary, when it didn't have to be. I also think this metaphor could have been problematic because she earlier said she was studying music, likely something she greatly enjoys. Suggesting (even remotely) that she might have to give up music to progress forward I think was a gaffe on my part. Sorry also about the noise. While we both likely understand that I have no control over the background noise in this spot, I am sorry for the challenging audio. Something that comes with filming in public, I suppose. Recorded w/Go-Pro. Edited w/PowerDirector. The views addressed here are mine and mine alone, and are not necessarily shared by members of my family and friends.
On Thursday’s Mark Levin Show, Senator Chuck Schumer made comments on climate change alleging that it is destroying our country, however, there was no mention of the crisis at our border. Suggesting that laws can somehow regulate how hot or cold the climate is, is absurd. Schumer noted that this June will be the hottest June on record in his attempt to use the government to control the climate. Then, Mediate has made a grotesque abuse of this program's comments and they should be ashamed of trying to capitalize on any condition that Robert Mueller may, or may not, have. Later, Andrew McCabe takes to the cable news shows to criticize Mueller despite being himself under investigation for allegedly illegally leaking classified information to the media. Afterward, Iran test-fired a ballistic missile and the code pink Republicans will probably blame America first. Learn more about your ad choices. Visit megaphone.fm/adchoices
On Thursday’s Mark Levin Show, Senator Chuck Schumer made comments on climate change alleging that it is destroying our country, however, there was no mention of the crisis at our border. Suggesting that laws can somehow regulate how hot or cold the climate is, is absurd. Schumer noted that this June will be the hottest June on record in his attempt to use the government to control the climate. Then, Mediate has made a grotesque abuse of this program's comments and they should be ashamed of trying to capitalize on any condition that Robert Mueller may, or may not, have. Later, Andrew McCabe takes to the cable news shows to criticize Mueller despite being himself under investigation for allegedly illegally leaking classified information to the media. Afterward, Iran test-fired a ballistic missile and the code pink Republicans will probably blame America first. Learn more about your ad choices. Visit megaphone.fm/adchoices
Find YOUR Way To Run Your Business! Show note links: For more, head over to: www.franexcell.com/ For more information or to apply for The Proactive Pants Mastermind: https://www.franexcell.com/proactivepants Book in a discovery call to see how I can help you: https://calendly.com/franexcell/30min To join my Free Facebook Community for daily mindset tips and tricks: https://www.facebook.com/groups/franexcellcommunity/ Download your Free Procrastination Buster here: https://franexcell.lpages.co/procrastinationbuster/ Make sure you’re following me on Instagram @franexcellcoach and tag me into your key takeaways! Find YOUR way to run your business! Find YOUR way to run your own business. Are you running and marketing your business based on the ‘exact 10 steps’ someone else used? Or using techniques with an energy of ‘this doesn’t feel right’ but doing it anyway because it’s worked for other people? How’s it working out for you? Recently I attended a 3 day workshop to complete a diploma in internet marketing (even though I have a Bsc degree in communications, 15 years experience in media and over 2 years in my own business...but my ‘need’ for pieces of paper to validate my knowledge is a story for another day and another episode ha!) I left feeling totally flat, and a little miffed to be honest. For a long time the online marketing ‘tactics’ have been bothering me. I see more and more, the ways in which people try to manipulate, hard sell and let’s be honest downright ‘dupe’. The ‘live’ webinars that aren’t live, even down to pretending you can chat to the host...but for some reason there must be a bug when you use it. All the times you see ‘I know I shouldn’t do this BUT’ posts *enters another funnel. The #vulnerability and thinly veiled sales pitches in groups...we all see you! The countdown timers that just start counting down again and the offer doesn’t ‘disappear’. The affiliate marketing for some seriously shady products. Rule of thumb...if you don’t want to put your name or your face to it, you probably shouldn’t be selling it! The ‘we had so many people say they missed the deadline so we’ve reopened for 24 more hours’ or ‘we’ve literally JUST come up with this payment plan and reopening for 24 more hours’. Suggesting to affiliate for systems you’ve never used, programmes you’ve never been through, without a care in the world for the people at the other end who buy. A lot of this was covered at the training. I took my husband who is SUPER anti marketing and I honestly thought he might pluck his own eyes out at some points. When questioned about how to sell something less tangible than the ‘make 6 figures in 6 months’ claims the response was simply ‘change what you’re selling.’ I choose to be different. I won’t make wild claims that need a disclaimer or ‘not typical results’displayed next to it. I won’t ‘own’ results that my clients have got because THEY’VE done the work, I know what it feels like because i’ve had it done to me! I'm just here to facilitate, teach, coach and mentor them to where they want to be using all the knowledge i’ve spent years, and paid a flippin fortune to learn. Does this mean it’s harder? Yes absolutely. But am I in integrity and building my business the way I want to? Yes, absolutely. Do I sleep well at night? Yes absolutely. Now don’t get me wrong, sometimes, understanding the psychology of why people buy can be just as helpful for the person BUYING just as much as the person selling so I get it, I really do and a lot of it I really do agree with. Limited availability and time sensitive offers can help us invest in ourselves when issues of worth may have stopped us before. It can help us make the right decision for us, get us off the fence and i’ve been grateful for it more than once. Change is hard and our brain will work against us every step of the way because it’s misguided intentions are to keep us safe. We make it harder on ourselves and often the sense of relief when i’ve made the decision to invest in something high ticket is liberating. I wouldn’t have got here if it weren’t for some of the tactics. But, when it’s done with integrity and you’re telling the truth. When there really are only X numbers of spots. And the offer really does expire at X time. Also don’t get me wrong again, I don’t believe EVERY marketer works in this way, there are CERTAINLY people who ARE marketing with integrity. It just feels like there’s less of them these days because it’s so noisy out there. It makes me sad when I see people who’ve ‘tried’ all the ‘exact step’ systems and it’s not worked for THEIR business. Part of the reason for that is they usually miss out a TONNE of the steps before they even tell you what the first is! It leaves people feeling less than. It leaves people wondering what’s wrong with them. In worst case scenarios they accept failure and quit. I’ve fallen for it too. I’ve lost count how many of those ‘this is EVERYTHING you need to have a business JUST like mine’ scripts i’ve bought into. The trouble is, most of the time, I don’t want a business ‘just like theirs’ at all! I don’t actually WANT to do some of the things they’re telling me to so I sabotage myself and make excuses. I want MY business, MY way, that fits into MY life, and i’m pretty sure you do too. You don’t want to be another cookie cutter, there’s more to you than that. So don’t beat yourself up when someone else’s exact steps don’t work for you, it’s not your fault. So you need to be honest with yourself about what you ACTUALLY want. Don’t use any ‘tactics’ that make you feel icky. (Please do NOT lump sales in general into this one and use it as an excuse not to do it, it’s time to reframe sales into being of service, you have to sell so people know you can help them solve their problems!) Because guess what, if something is making you feel ‘icky’ you’ll subconsciously sabotage your efforts anyway. I get that some of these tactics ‘work’ but I do believe the tide is turning and turning fast and they won’t work for long. The fake ‘live’ webinars, the funnels that get you somewhere for free, upsell you to the next level and then upsell you again. It’s leaving people in a constant state of feeling like they ‘need’ something else to get heir business to where they want it to go. Another tactic. Another strategy. But you don’t. You just need to work out what’s going on in your noggin, work out how you actually want to run your business, take any learnings you already have or learn from someone you really trust and find YOUR way to market. It’s no surprise to me that my podcast and instagram are my biggest audiences. I actually ENJOY them. They both feel pretty effortless for me to be on. It’s also no surprise to me that I tend to find clients from things i’ve done in person. Whether that’s speaking at an event or doing a training in someone else's group or programme. I REALLY enjoy in person. I come alive when I’m teaching people what I know. PLUS I am super picky about who I work with, it needs to be right from both sides so meeting them in person works for me. It’s also how I learn best myself, so in person is a big part of and something I introduced to the 1:1 programmes I offer so I can make sure people learn as much as possible. And i’m a hugger, let’s be honest! Due to that, I’m in the rumble at the moment of what I want MY focus to be and how I want to show up ‘online’ without just being another contributor to the noise and make sure i’m making the impact in the right places. So there will be big (but exciting!) changes afoot in MY business. This stuff is fluid. You just need to learn to listen to yourself and be super self aware to notice when you’re sabotaging yourself and most importantly, why. What thoughts are going on for you? Where is something feeling ‘off’ or ‘heavy’ and what can you do to change it. Questioning what YOU want and revisiting that question regularly is SO key. When you’re creating something or doing something that you either don’t really want deep down, or that feels out of whack with your values you WILL sabotage yourself. When your unconscious is running the show and you have ingrained habits and belief systems that aren’t aligning with what your conscious is trying to do it WILL sabotage your efforts. So what do you LOVE in your business and how you market it right now? What do you want to change? Please give yourself a break if you’ve tried an ‘exact’ step method and it hasn’t worked for you. They’ve either not given you the whole story or your unconsciously sabotaging it. You’ve just got to find YOUR thing. The thing that you LOVE doing and a way you LOVE marketing. Just remember, there are people out there doing it. If it’s possible for them it’s possible for you. 100%. Choose who you want to learn from and model how they’re doing it. Don’t sacrifice your integrity and your values because someone is telling you it’s the only way, because it isn’t! If you know that now is the time to start changing things for yourself and want to explore this further, have any questions or want some accountability to make sure you’re doing the things you need to then please book in a free discovery call so we can see what needs to happen to get you from where you’re at right now, to the successful business owner you know you can be!! Fx
ANNOUNCEMENTS: INFOSEC CAMPOUT TICKETS ARE STILL ON SALE. Go to https://www.infoseccampout.com for Eventbrite link and more information. Part 2 of our Discussion with Chris Sanders (@chrissanders88) Topics discussed: Companies dropping existing frameworks for ATT&CK Matrix, why? Rural Technology Fund - What it is, how does it work, Who can help make it more awesome. https://chrissanders.org/2019/05/infosec-mental-models/ I’ve argued for some time that information security is in a growing state of cognitive crisis… Demand outweighs supply Because so many organizations need experience, they are unable to appropriately invest in entry-level jobs and devote the necessary time for internal training. That’s an HR and hiring manager issue, right? --brbr No. --bboettcher Information cannot be validated or trusted There are few authoritative sources of knowledge about critical components and procedures. Large systemic issues persist with no ability to tackle them in a large, mobilized, or strategic manner. The industry is unable to organize or widely combat the biggest issues they face. Groups of individuals, everyone thinking they have the ‘right answer’, just like linux flavors --brbr https://www.fireeye.com/blog/threat-research/2015/06/caching_out_the_val.html https://www.helpnetsecurity.com/2018/07/10/windows-shimcache-threat-hunting/ Dependence on tools: http://traffic.libsyn.com/brakeingsecurity/2016-006-Moxie_vs_Mechanism-dependence_on_tools.mp3 https://en.wikipedia.org/wiki/Cognitive_revolution https://buzzmachine.com/2019/04/25/a-crisis-of-cognition/ How do we solve it? We must thoroughly understand the processes used to draw conclusions. S.M.A.R.T.? Experts must develop repeatable, teachable methods and techniques. Educators must build and advocate pedagogy that teaches practitioners how to think. https://www.maximumfun.org/shows/sawbones - sawbones podcast (amanda mentioned) Mental Model? We use them all the time? Gotta simplify the complex... Distribution and the Bell Curve Operant Conditioning https://www.latimes.com/science/la-sci-emotional-stereotypes-about-women-20190530-story.html The Scientific Method Applied Models 13 Organ Systems 4 Vital Signs 10 Point Pain scale Defense in Depth OSI model Investigation Process https://en.wikipedia.org/wiki/Inductive_reasoning Model Desperation Companies dumping existing models and embracing something else The problem is that we’re model hungry and we’ll rapidly use and abuse any reasonable model that presents itself. Ultimately, we want good models because we want a robust toolbox. But, not everything is a job for a hammer and we don’t need fourteen circular saws. What makes a good model? Simple Useful Imperfect? (wuh?)-brbr Creating models Begins by asking a question… (what is the weather going to look like tomorrow? --brbr) What defines the sandwich? (kind of like “https://en.wikipedia.org/wiki/Theory_of_forms” --brbr) Discuss the Rural Tech Fund https://twitter.com/RuralTechFund https://ruraltechfund.org/ Practical Threat Hunting - https://twitter.com/chrissanders88/status/1133388347194454018 Practical Packet Analysis - https://nostarch.com/packetanalysis3 Suggesting books: https://www.amazon.com/Thinking-Fast-Slow-Daniel-Kahneman/dp/0374533555 https://www.amazon.com/Undoing-Project-Friendship-Changed-Minds/dp/0393354776 More references on Chris’ site https://chrissanders.org/2019/05/infosec-mental-models/ Book Club Cult of the dead cow - June Tribe of Hackers - July The Mastermind - August The Cuckoo’s Egg - September Check out our Store on Teepub! https://brakesec.com/store Join us on our #Slack Channel! Send a request to @brakesec on Twitter or email bds.podcast@gmail.com #Brakesec Store!:https://www.teepublic.com/user/bdspodcast #Spotify: https://brakesec.com/spotifyBDS #RSS: https://brakesec.com/BrakesecRSS #Youtube Channel: http://www.youtube.com/c/BDSPodcast #iTunes Store Link: https://brakesec.com/BDSiTunes #Google Play Store: https://brakesec.com/BDS-GooglePlay Our main site: https://brakesec.com/bdswebsite #iHeartRadio App: https://brakesec.com/iHeartBrakesec #SoundCloud: https://brakesec.com/SoundcloudBrakesec Comments, Questions, Feedback: bds.podcast@gmail.com Support Brakeing Down Security Podcast by using our #Paypal: https://brakesec.com/PaypalBDS OR our #Patreon https://brakesec.com/BDSPatreon #Twitter: @brakesec @boettcherpwned @bryanbrake @infosystir #Player.FM : https://brakesec.com/BDS-PlayerFM #Stitcher Network: https://brakesec.com/BrakeSecStitcher #TuneIn Radio App: https://brakesec.com/TuneInBrakesec
https://chrissanders.org/2019/05/infosec-mental-models/ I’ve argued for some time that information security is in a growing state of cognitive crisis… Demand outweighs supply Because so many organizations need experience, they are unable to appropriately invest in entry-level jobs and devote the necessary time for internal training. That’s an HR and hiring manager issue, right? --brbr No. --bboettcher Information cannot be validated or trusted There are few authoritative sources of knowledge about critical components and procedures. Large systemic issues persist with no ability to tackle them in a large, mobilized, or strategic manner. The industry is unable to organize or widely combat the biggest issues they face. Groups of individuals, everyone thinking they have the ‘right answer’, just like linux flavors --brbr https://www.fireeye.com/blog/threat-research/2015/06/caching_out_the_val.html https://www.helpnetsecurity.com/2018/07/10/windows-shimcache-threat-hunting/ Dependence on tools: http://traffic.libsyn.com/brakeingsecurity/2016-006-Moxie_vs_Mechanism-dependence_on_tools.mp3 https://en.wikipedia.org/wiki/Cognitive_revolution https://buzzmachine.com/2019/04/25/a-crisis-of-cognition/ How do we solve it? We must thoroughly understand the processes used to draw conclusions. S.M.A.R.T.? Experts must develop repeatable, teachable methods and techniques. Educators must build and advocate pedagogy that teaches practitioners how to think. https://www.maximumfun.org/shows/sawbones - sawbones podcast (amanda mentioned) Mental Model? We use them all the time? Gotta simplify the complex... Distribution and the Bell Curve Operant Conditioning https://www.latimes.com/science/la-sci-emotional-stereotypes-about-women-20190530-story.html The Scientific Method Applied Models 13 Organ Systems 4 Vital Signs 10 Point Pain scale Defense in Depth OSI model Investigation Process https://en.wikipedia.org/wiki/Inductive_reasoning Model Desperation Companies dumping existing models and embracing something else The problem is that we’re model hungry and we’ll rapidly use and abuse any reasonable model that presents itself. Ultimately, we want good models because we want a robust toolbox. But, not everything is a job for a hammer and we don’t need fourteen circular saws. What makes a good model? Simple Useful Imperfect? (wuh?)-brbr Creating models Begins by asking a question… (what is the weather going to look like tomorrow? --brbr) What defines the sandwich? (kind of like “https://en.wikipedia.org/wiki/Theory_of_forms” --brbr) Discuss the Rural Tech Fund https://twitter.com/RuralTechFund https://ruraltechfund.org/ Practical Threat Hunting - https://twitter.com/chrissanders88/status/1133388347194454018 Practical Packet Analysis - https://nostarch.com/packetanalysis3 Suggesting books: https://www.amazon.com/Thinking-Fast-Slow-Daniel-Kahneman/dp/0374533555 https://www.amazon.com/Undoing-Project-Friendship-Changed-Minds/dp/0393354776 More references on Chris’ site https://chrissanders.org/2019/05/infosec-mental-models/ Book Club Cult of the dead cow - June Tribe of Hackers - July The Mastermind - August The Cuckoo’s Egg - September Check out our Store on Teepub! https://brakesec.com/store Join us on our #Slack Channel! Send a request to @brakesec on Twitter or email bds.podcast@gmail.com #Brakesec Store!:https://www.teepublic.com/user/bdspodcast #Spotify: https://brakesec.com/spotifyBDS #RSS: https://brakesec.com/BrakesecRSS #Youtube Channel: http://www.youtube.com/c/BDSPodcast #iTunes Store Link: https://brakesec.com/BDSiTunes #Google Play Store: https://brakesec.com/BDS-GooglePlay Our main site: https://brakesec.com/bdswebsite #iHeartRadio App: https://brakesec.com/iHeartBrakesec #SoundCloud: https://brakesec.com/SoundcloudBrakesec Comments, Questions, Feedback: bds.podcast@gmail.com Support Brakeing Down Security Podcast by using our #Paypal: https://brakesec.com/PaypalBDS OR our #Patreon https://brakesec.com/BDSPatreon #Twitter: @brakesec @boettcherpwned @bryanbrake @infosystir #Player.FM : https://brakesec.com/BDS-PlayerFM #Stitcher Network: https://brakesec.com/BrakeSecStitcher #TuneIn Radio App: https://brakesec.com/TuneInBrakesec
In this riveting climax to the 3-part series of Deadly Sins of Online Dating, we’ll give you the final thirteen sins and teach you how to avoid them at all costs. In this episode: – Using general or filler words to make your partner jealous such as being “out with friends”– Being intentionally boring– Not answering direct questions and avoiding them at all costs– Getting offended that the man was “too” this or that– Sending your relationship to the graveyard by suggesting you, “like to get to know people on the app before meeting or talking”– Not talking or communicating in any way shape or form between setting up a date and your actual in person date– Being “bad with your phone,” admitting it, and doing nothing about it– Using phrases like “I just assumed you were…” to make excuses for yourself– Suggesting that all your partners behavior is a red flag– Upholding the mentality that a partner should prove themselves to you or thinking you’re better than your partner– Constantly demonstrating not merely a lack of punctuality, but calling when you’re already late to let them know you will be even more late– Encouraging your date to forget about you before even meeting– Suggesting you “just cancel everything” because of one reschedule– Being totally non-committal– Freaking out because you don’t like his approach even though he has no idea who you are, where you’re from, what your morals are, how you like to be treated– Speaking in generalities and not really caring, “Tell me something about yourself!”– Interviewing your date heavily but not sharing anything about yourself– Telling a guy how you’d love to see him and can’t wait to see him but never taking action on it Are you ready to come closer? Closeness Coaching for sex, intimacy, relationships and quality of life: https://getcloseness.com/coaching Subscribe to Closeness on YouTube: http://www.youtube.com/closeness?sub_confirmation=1 Please consider donating to our Patreon: http://www.patreon.com/closeness
On Tuesday's Mark Levin Show, The Council of American Islamic Relations (CAIR) is now demanding that Fox News drop Jeanine Pirro and Tucker Carlson or ask their advertisers to walk away from Fox News. This is blackmail by CAIR and we'll call out the media and CAIR for who they really are. Also, veteran news anchor Ted Koppel has come out again saying that the media is no longer the reservoir of objectivity that it once was. Stating that becoming the enemy of the President is not the role of the press. The immediate rise of Alexandria Ocasio-Cortez is a prime example of how the media uses their influence to shape the truth instead of report on it objectively. Nihad Awad from CAIR has ties to Hamas and the Muslim brotherhood. CAIR has long been considered a front group for Hamas and was named an unindicted co-conspirator in the Holyland federal court case. Then, there are new calls for additional Supreme Court seats and a continued effort to undermine the electoral college. Afterwards, the Trump Administration wins another Supreme Court victory upholding the government's position on detention. Lastly, our educational system is indoctrinating our youth under the guise of social activism, promoting the ideas of collectivism over Americanism. Suggesting that destruction of our institutions is necessary in order to appropriately rebuild our nations institution. Learn more about your ad choices. Visit megaphone.fm/adchoices
On Tuesday's Mark Levin Show, The Council of American Islamic Relations (CAIR) is now demanding that Fox News drop Jeanine Pirro and Tucker Carlson or ask their advertisers to walk away from Fox News. This is blackmail by CAIR and we'll call out the media and CAIR for who they really are. Also, veteran news anchor Ted Koppel has come out again saying that the media is no longer the reservoir of objectivity that it once was. Stating that becoming the enemy of the President is not the role of the press. The immediate rise of Alexandria Ocasio-Cortez is a prime example of how the media uses their influence to shape the truth instead of report on it objectively. Nihad Awad from CAIR has ties to Hamas and the Muslim brotherhood. CAIR has long been considered a front group for Hamas and was named an unindicted co-conspirator in the Holyland federal court case. Then, there are new calls for additional Supreme Court seats and a continued effort to undermine the electoral college. Afterwards, the Trump Administration wins another Supreme Court victory upholding the government's position on detention. Lastly, our educational system is indoctrinating our youth under the guise of social activism, promoting the ideas of collectivism over Americanism. Suggesting that destruction of our institutions is necessary in order to appropriately rebuild our nations institution. Learn more about your ad choices. Visit megaphone.fm/adchoices