Podcasts about Culex

Detienen a 2 por tráfico de personas en ChiapasBanxico prevé un crecimiento de 250 a 350 mil empleosGobierno de Maduro anunció sanciones a extranjeros  Más información en nuestro Podcast

Milan Uyeno is in the booth once again, bringing some great glitchy ambient and modern classical, with a small dip into some amazing jazz.Playlist: Ryuichi Sakamoto - 20220302 - sarabandeSahil Chugh - CharadeMark Limacher - "​.​.​.​or was it that​.​.​.​" // (trio)poliana esperança - Dentro de um todocatstem - pharmacyBuildings and Food - Found ObjectsCash, featuring anem0s & JHL - PassthroughKashiwa Diasuke - algo-Rhythm #02Asleep Country - Sepulcric Hall / The Burn WardTommy Crane - Early 2000'sKamasi Washington - PrologueNala Sinephro - Continuum 10Michael Davidson, Dan Fortin - Berlin IVfractanisharmonicoo - 白昼夢診断 (Daydream Diagnosis)Koop - Absolute Space (Jazzanova Remix)Bent Spoon Trio - The ContinentalSAINERINE - Purity and ObedienceJaakko Metsäpelto - Culex/f - Yuri or Dead Caliber

Pojasnila in nasveti epidemiologinje Alenke Trop SkazaTropske bolezni v Sloveniji nas nič več ne presenečajo. Do konca avgusta so pri nas potrdili že en primer Zike, štiri primere malarije, sedemnajst denge in tri primere vročice Zahodnega Nila. Letošnji primeri okužbe z virusom Zahodnega Nila kljub temu izstopajo. Tokrat so se oboleli z virusom okužili znotraj Slovenije; nihče od njih ni bil v tujini. Preseneča tudi, da se je pri vseh treh okužba zapletla do te mere, da so potrebovali zdravljenje v UKC Maribor. Za več informacij in pojasnil smo v Celje poklicali prim. doc. dr. Alenko Trop Skaza z Nacionalnega inštituta za javno zdravje. Foto: Samec komarja Culex (v ospredju/spodaj desno) in transmisijska elektronska mikrografija, ki prikazuje delce virusa Zahodnega Nila (obarvani rumeno) v okuženi celici. NIAID/ Flickr, cc

Editorial | Jején y culex, los nuevos enemigos

It's the last week of Carnivorous Plant Month.

Nesta edição do "CBN Meio Ambiente e Sustentabilidade", o comentarista Marco Bravo, na série "Mudanças Climáticas X Saúde" traz o alerta com relação aos riscos da leishmaniose e filariose. O que são? A leishmaniose é uma doença infecciosa, porém, não contagiosa, causada por parasitas do gênero Leishmania. Os parasitas vivem e se multiplicam no interior das células que fazem parte do sistema de defesa do indivíduo, chamadas macrófagos. É uma doença de evolução longa, podendo durar alguns meses ou até ultrapassar o período de um ano. Já a Filariose Linfática (Elefantíase) é uma doença parasitária crônica, considerada uma das maiores causas mundiais de incapacidades permanentes ou de longo prazo. É causada pelo verme nematoide Wuchereria Bancrofti e transmitida pela picada do mosquito Culex quiquefasciatus (pernilongo ou muriçoca) infectado com larvas do parasita. As informações são do Ministério da Saúde. Ouça a conversa completa!

L'encefalite giapponese è una malattia virale trasmessa dalla puntura di una zanzara. Diversamente da quanto suggerisca il nome, l'encefalite giapponese è diffusa in una vasta area del pianeta che va dall'India fino all'Australia. Fra le forme di encefalite virale, l'encefalite giapponese non è certo la più frequente, ma sicuramente fra le più gravi. Gli esiti dell'encefalite giapponese possono essere devastanti. In questa puntata del podcast di Erreconzero, partendo da diverse storie di pazienti che hanno contratto l'encefalite giapponese, parleremo della malattia, della sua diffusione e di come prevenirla. Se avete intenzione di partire verso oriente, non mancate di ascoltare attentamente questa puntata

Mamileiros e mamiletes, O Mamilos esteve na COP 28, pelo segundo ano consecutivo, a convite do Pacto Global da ONU no Brasil e no programa de hoje, o que vocês vão ouvir são as conversas que tivemos com pessoas que estão liderando as transformações necessárias à adaptação à mudança climática no Brasil. Esse programa foi feito pra você que tá ouvindo falar de COP o tempo inteiro, sabe que é importante e tá aí com várias abas abertas sobre o assunto mas não tá dando conta de acompanhar. Nossa missão aqui é, em pouco mais de uma hora, contar pra vocês pra que serve a COP, como o encontro funciona, como o Brasil tem atuando dentro das pautas debatidas e o que ficou estabelecido nesta edição acontecida em Dubai. Dá o play e vem com a gente! _____ SBP Quem nunca passou um tempão tentando matar todos os pernilongos do quarto antes de dormir? E claro que é só apagar a luz e deitar na cama que já vem um zumbido no ouvido pra te mostrar que tinham mais mosquitos escondidos prontinhos pra atrapalhar seu sono. Pra resolver esse problema, SBP lançou um produto novo com uma tecnologia revolucionária. O SBP com Ação Magnética Aerossol caça e mata até 100% dos mosquitos escondidos e difíceis*. Parece magia, mas é verdade: o produto caça e mata 100% dos mosquitos e deixa sua casa e sua família protegidas. Já pensou? Uma ótima solução para acabar com o zumbido na hora do sono. Amar é proteger, e proteger é SBP. Saiba mais em: sbpprotege.com.br (*) 100% de eficácia em testes de laboratório contra mosquitos Aedes aegypti (escondidos) e Culex quinquefasciatus (difíceis). _____ FALE CONOSCO . Email: mamilos@mamilos.me _____ CONTRIBUA COM O MAMILOS Quem apoia o Mamilos ajuda a manter o podcast no ar e ainda participa do nosso grupo especial no Telegram. É só R$9,90 por mês! Quem assina não abre mão. https://www.catarse.me/mamilos _____ Equipe Mamilos Mamilos é uma produção do B9 A apresentação é de Cris Bartis e Ju Wallauer. Pra ouvir todos episódios, assine nosso feed ou acesse mamilos.b9.com.br Quem coordenou essa produção foi Beatriz Souza. A edição foi de Mariana Leão e as trilhas sonoras, de Angie Lopez. A coordenação digital é feita por Agê Barros. O B9 tem direção executiva de Cris Bartis, Ju Wallauer e Carlos Merigo. O atendimento e negócios é feito por Telma Zennaro.

Mamileiros e mamiletes, há algumas semanas, fizemos o Mamilos 419 sobre como educar nossos filhos entre o autoritarismo e a permissividade. A conversa foi tão boa, que terminamos o programa com a sensação de que ainda tinha tanto a ser dito que precisávamos de uma parte dois. E pelos comentários que recebemos, vocês também ficaram querendo esticar esse papo! Então, aqui estamos pra segunda parte dessa conversa sobre educação com limites. Naquele primeiro programa, falamos muito sobre o desafio de se equilibrar entre ser autoritário ou permissivo. Neste, queremos focar mais em situações práticas e em como podemos agir da melhor forma diante delas. E como cada faixa etária tem seus desafios particulares, nesse programa vamos focar na fase da pré adolescência. Quais são os limites para dar autonomia sem deixar de proteger? E vamos em boa companhia, sentam na mesa com a gente Ariella Wanner, pedagoga, especializada em neurociência das emoções, e Thais Basile, psicanalista, especialista em psicopedagogia institucional. Esse programa também foi publicado em vídeo no nosso canal do Youtube. Dá o play e vem com a gente! _____ SBP Quem nunca passou um tempão tentando matar todos os pernilongos do quarto antes de dormir? E claro que é só apagar a luz e deitar na cama que já vem um zumbido no ouvido pra te mostrar que tinham mais mosquitos escondidos prontinhos pra atrapalhar seu sono. Pra resolver esse problema, SBP lançou um produto novo com uma tecnologia revolucionária. O SBP com Ação Magnética Aerossol caça e mata até 100% dos mosquitos escondidos e difíceis*. Parece magia, mas é verdade: o produto caça e mata 100% dos mosquitos e deixa sua casa e sua família protegidas. Já pensou? Uma ótima solução para acabar com o zumbido na hora do sono. Amar é proteger, e proteger é SBP. Saiba mais em: sbpprotege.com.br (*) 100% de eficácia em testes de laboratório contra mosquitos Aedes aegypti (escondidos) e Culex quinquefasciatus (difíceis). _____ FALE CONOSCO . Email: mamilos@mamilos.me _____ CONTRIBUA COM O MAMILOS Quem apoia o Mamilos ajuda a manter o podcast no ar e ainda participa do nosso grupo especial no Telegram. É só R$9,90 por mês! Quem assina não abre mão. https://www.catarse.me/mamilos _____ Equipe Mamilos Mamilos é uma produção do B9 A apresentação é de Cris Bartis e Ju Wallauer. Pra ouvir todos episódios, assine nosso feed ou acesse mamilos.b9.com.br Quem coordenou essa produção foi Beatriz Souza. A edição foi de Mariana Leão e as trilhas sonoras, de Angie Lopez. A coordenação digital é feita por Agê Barros. O B9 tem direção executiva de Cris Bartis, Ju Wallauer e Carlos Merigo. O atendimento e negócios é feito por Telma Zennaro.

Grand événementCollège de FranceLa ville du futurAnnée 2023-2£024Colloque - La ville du futur : La ville du futur, face au risque entomologiqueIntervenant(s)Didier Fontenille, directeur de recherche émérite, IRDRésuméPour faire face aux futurs enjeux urbains, de nombreuses villes se sont engagées dans un processus de « renaturation », à travers des programmes de végétalisation et d'actions visant à augmenter la biodiversité. Ces actions ont de nombreux impacts positifs sur la santé et le bien-être des habitants. En revanche, les éventuels impacts négatifs sont encore rarement appréhendés. Parmi ceux-ci, une augmentation de la biodiversité des arthropodes vecteurs d'agents infectieux, des hôtes vertébrés réservoirs, des agents infectieux eux-mêmes, en lien avec la création de nouvelles niches écologiques.Nous prendrons quelques exemples concernant les punaises de lits, les moustiques Aedes vecteurs de dengue, chikungunya, Zika, les moustiques Culex vecteurs des virus West Nile et Usutu, les Anopheles responsables de paludisme urbain. Nous verrons comment la création de parcs, corridors verts, forêts urbaines peut permettre l'introduction et l'installation de phlébotomes et de tiques impliqués dans des maladies humaines et animales. Les effets bénéfiques de la renaturation des villes sur la santé des humains sont indéniables. Cependant, pour ne pas compromettre le processus vertueux en cours, l'identification, la surveillance et la gestion d'éventuels impacts négatifs liés aux maladies vectorielles sont nécessaires.------------Le futur est dans la ville. En 2022, 56 % de la population mondiale, soit environ 4,4 milliards d'habitants, vivaient en milieu urbain. Cette tendance, si elle se maintenait, ferait que d'ici 2050, 7 personnes sur 10 seront citadines.Cette concentration humaine est source de richesse économique et culturelle, mais induit évidemment des risques, des fragilités, des inégalités parfois extrêmes. Elle est aussi génératrice d'effets environnementaux indésirables. La Banque mondiale estime que les villes représentent actuellement près des 2/3 de la consommation mondiale d'énergie et 70 % des émissions planétaires de gaz à effet de serre. Responsable certes, mais aussi victime de l'accélération des changements environnementaux, en particulier climatiques, caractéristiques de l'anthropocène.Ainsi s'impose la nécessité d'adapter les grands ensembles urbains à ces défis environnementaux. Certaines métropoles sont menacées par la montée des eaux océaniques. D'autres – parfois les mêmes – sont menacées par les accidents climatiques extrêmes, précipitations massives génératrices d'inondations brutales, canicules, voire simplement augmentation soutenue des températures moyennes impactant violemment populations et infrastructures urbaines. À ces défis vient s'ajouter la gestion du risque sanitaire : qualité et disponibilité de l'eau, risque épidémique, maladies liées à la pollution. L'« exposome urbain » reste à appréhender dans sa globalité, sans parler des altérations de la biodiversité microbienne, animale et végétale.Ces pressions environnementales, devenues globales – à des degrés variables – à l'échelle planétaire, sont aussi de puissants révélateurs et moteurs d'inégalités, que ce soit dans une seule et même ville où elles creusent un fossé entre populations aisées et populations marginalisées ou entre des villes situées sur des continents et dans des contextes socioéconomiques différents. L'urbanisation galopante est ainsi principalement portée par la poursuite du développement en Afrique et en Asie.Les politiques de la ville devront tenir compte de ces exigences d'adaptation, à l'intersection des impératifs socio-économiques, environnementaux, climatiques et sanitaires, pour bâtir un espace urbain résilient et accueillant pour tous. Elles pourront s'inspirer d'exemples d'adaptabilité de métropoles soumises de longue date aux excès climatiques. L'acceptabilité sociale et économique des adaptations indispensables à la conception de la ville du futur est un autre défi pour les politiques urbaines à venir.Le Collège de France, par le biais de son initiative Avenir Commun Durable, espère apporter une contribution aux réflexions sur ces questions complexes. Pour ce faire, il s'appuie sur un panel large d'intervenants couvrant un vaste champ de disciplines.À quoi donc ressemblera la ville du futur ?L'initiative Avenir Commun Durable bénéficie du soutien de la Fondation du Collège de France, de ses grands mécènes La Fondation Covéa et TotalEnergies et de ses mécènes Faurecia et Saint-Gobain.

This week on NintenDomain, we talk about Super Mario RPG and the Black Friday deals!! Support the show at: www.patreon.com/nintendomainpodcast Music: Intro: Super Mario RPG: Happy Adventure, Delightful Adventure Break 1: Super Mario RPG: Still, The Road is full of Dangers Break 2: Super Mario RPG: Let's Go Down the Wine River Outro: Super Mario RPG: The END! Topic Times: 00:01:32 Black Friday Deals and Gifts AEW Fight Forever Season 2 Sonic Superstars 01:07:38 Got Item! Air Twister Dave the Diver 01:23:52 Super Mario RPG  

La Corte Suprema americana ha pubblicato un suo codice etico ma con polemiche, le zanzare ce le teniamo fino a dicembre e il Nepal vuole bandire Tiktok. Ci sono notizie da Israele, la Banca d'Italia dice cose un minimo positive e David Cameron è tornato in politica. Buon martedì

durée : 00:03:33 - Le moustique Culex et le moustique Aédes - par : Nathalie Mazet - Le moustique commun est l'espèce la plus commune du genre Culex présent dans l'hémisphère nord, le moustique aedes ou tigre originaire d'Asie du sud-est. est l'une des espèces les plus invasives au monde, présente dans 100 pays sur les 5 continents

Thule Squadron Radio is an X-Wing podcast broadcasting from Reykjavík, Iceland and Copenhagen, Denmark. Episode 131 - Weiland of the North Stephen Weiland joins the cast for a rundown of news, beef, Thule challenges, UKGE, Culex store champ and more! Like our facebook page @ Thulesquadronradio and join the discussion  Like out Twitch channel @ thule_squadron Like our youtube channel @ Thule Squadron Support us on Patreon @ Thulesquadronradio  Join our discord server @ https://discord.gg/XQVbz7grHk Email us @ Thulesquadronradio@gmail.com  Hosts are: Gísli Baldur Bragason Jan Ullerup Guest is: Stephen Weiland

This Month, host Bill McGeeney is joined by Michael Rymer of the Dark Sky (formerly International Dark Sky Association) and Youth Advocate, Bonnie Peng. Learn more at LightPollutionNews.com.Articles:Is light pollution making darkness a luxury? Here Come the Lumens The New Light Is Bad There's something off about LED bulbs — which will soon be, thanks to a federal ban, the only kind you can buy. "Mysterious spiral" that looks like hazy, glowing galaxy seen hovering in Alaska's northern lightsWhy It's Time for a Worldwide Lights-Out Program The Consequences of Light Pollution Light Pollution Disrupts Seasonal Differences in the Daily Activity and Metabolic Profiles of the Northern House Mosquito, Culex pipiens Blue Vigil developed a high intensity tethered LED array to a drone You're Definitely Suffering the Effects of Light Pollution—But We're Here to Help $3M in federal money coming to Norfolk for streetlight upgradesMayor Gloria highlights federal funding for streetlight repairs in multiple areas of San Diego Frederick, Md plans to update its street lighting Afraid of the Dark: The Safety of Light: A Short History of Light in Public Spaces Camden Working to Fix Street Light Outages to Help Make Community SaferNatural Surveillance for Crime and Traffic Accidents: Simulating Improvements of Street Lighting in an Older Community Research Article of the Month: Impact of Solid State Roadway Lighting on Melatonin in Humans Support the showLike what we're doing? For the cost of coffee, you can become a Monthly Supporter? Your assistance will help cover server and production costs.

Adam and Megabyte are back with an all new season! Brett and Alex grab their bug spray and get inside their mosquito nests for this one. Together they look at the second series of "The Tomorrow People: The Culex Experiment". How does this series stack up against "The Origin Story"? Only one way to find out! If you want to check out the series in it's entirety, here is the link: https://youtube.com/playlist?list=PL8vAvnjHeJNtA1zwSGVzv13XxBrdfefBL If you enjoy our content, support us on Patreon and join the Gakoids: www.patreon.com/splatattack Like & Subscribe on YouTube: Splat Attack! Podcast Follow us on Instagram: @SplatAttackPodcast Follow us on Reddit: SplatAttack2021 Follow us on TikTok: @splatattack2021 Thanks for tuning in, and we'll splat you later!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.09.523250v1?rss=1 Authors: Lapshin, D., Vorontsov, D. Abstract: The task of directional hearing faces most of the animals that possess ears. They approach this task in different ways, but the common trait is the usage of the binaural cues to find the direction to the source of sound. In insects, the task is further complicated by their small size and, hence, minute temporal and level differences between two ears. A way to overcome this problem is to receive the particle velocity component of sound rather than the pressure, as the former naturally involves directionality. However, even in this case, one ear is not enough for directional hearing: a single symmetric flagellar particle velocity receiver cannot discriminate between the two opposite directions along the vector of the sound wave. Insects that use flagellar auditory organs, and mosquitoes in particular, possess a pair of receivers, which presumes the usage of binaural hearing. Its mechanisms are expected to be significantly different from the ones typical for the pressure receivers. However, the directionality of flagellar auditory organs has received little attention. Here we measured the in-flight orientation of a female mosquito antennae and obtained detailed physiological mapping of the Johnston's organ directionality at the level of individual sensory units. By combining these data, we provided a three-dimensional model of the mosquito's auditory space. The natural orientation of the antennae together with angular distribution of sensory units in each of the Johnston's organs was found to be optimal for binaural hearing focused primarily in front of, above and below a flying mosquito. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Peste des petits ruminants (PPR) and Rift Valley Fever are examples of transboundary animal diseases having major consequences in terms of health and economics. PPR is a highly pathogenic viral disease infecting principally sheep and goats, but also some wild artiodactyls, camelids and suids. This disease circulates in large parts of Africa, Asia, Eurasia and Middle-East and it has recently appeared at the gates of Europe in Georgia (2016) and Bulgaria (2018). A vaccine sxiste and the disease is the target of an eradication campaign by 2030. RVF is an arbovirus also affecting small ruminants and camelids, but also cattle and can be transmitted to human. The virus is transmitted among ruminants through the bite of infected mosquitoes (belonging to the Aedes and Culex species) and to human through the direct contact with infected blood or tissues. The disease circulates mostly in most countries in North, East, West and Sahelian Africa as well as in the Arabian Peninsula. Despite the different way of transmission, transboundary animal movement is the most likely route of the spread of the two diseases. Even though the livestock trade is strictly regulated between endemic regions of the two diseases and most of the Mediterranean countries, regional, locally adapted strategies are needed to control the diseases efficiently. The aim of this talk is to provide a panorama of the epidemiological situation around Europe and provide some preliminary scenario for the introduction of the diseases, through animal movement, and risk of transmission due to the presence of competent vectors (only for Rift Valley Fever).

Covid'in ikinci yılını devireceğimiz şu günlerde grip salgını da sağolsun kendini gösterdi. ÜSYE bulguları ile gelen hastalarda acaba Covid mi? Grip mi? dilemmasını yaşamak yetmezmiş gibi komşudan gelen Batı Nil Virüsü (BNV) ile ilişkilendirilmiş ölüm haberlerine "eyvah" demedim diyemeyeceğim. Avrupa Hastalık Önleme ve Kontrol Merkezi (ecdc)'nin geçen haftaki verilerine göre 1 Ocak 2022 - 21 Eylül 2022 tarihleri arasında AB ülkelerinde 1000'e yakın pozitif vakanın 231'i Yunanistan'da bildirilmiş ve ölüm bildirimlerinin(51) 28'i İtalya, 20'si Yunanistan'da gözlenmiş. Hal böyle olunca eskilerin meşhur sözü " Komşuda pişer bize de düşer" sözü aklıma geldi. Malum önümüz kış, sezon açıldı. ÜSYE bulguları ile gelen hastaların ayırcı tanısına Batı Nil Ateşi'ni de eklememiz gerekebileceğini düşünerek sizlere bu yazıyı hazırladım. Keyifli okumalar dilerim. EPİDEMİYOLOJİ Batı Nil Ateşi, Japon ensefalit virüs antijen kompleksinin bir üyesi olan Batı Nil (WN) virüsü, ilk olarak 1937'de Uganda'nın Batı Nil eyaletinde hastadan alınan bir kan örneğinden izole edilmiş. İlk zamanlarda halk sağlığı açısından önemsiz olduğu düşünülmüş, ta ki 99 yılında Amerikan'nın New York şehrinde 62 ensafalit vakası çıkana kadar.​1​ İlk çalışmalar, Kuzey Amerika görülen WN virüsünün Orta Doğu kökenli olduğunu öne sürerken, sonraki analizler WN suşlarının Kuzey Afrika'dan geldiğini göstermiş. Avrupa'da ise ilk büyük salgın 1996'da Romanya'da gözlendi. O zamandan beri, İspanya, İtalya, Yunanistan, Ukrayna ve Rusya Federasyonu'na (Volgograd, Astrakchan ve Rostov) kadar uzanan sporadik insan vakaları rapor edildi. 2010'dan 2018'e kadar, Avrupa Birliği ülkelerinde 110 ila 991 nöroinvaziv hastalık vakası bildirilmiş.​2​ BULAŞ WN virüsünün enfeksiyonları " Culex" isimli dişi sivrisinek ısırıklarından kaynaklanır. Asıl konak kuşlardır. Virüs, sinek-kuş-sinek döngüsü içinde korunur. İnsanlar, atlar ve diğer memeliler tesadüfi veya son konakçıdırlar. İnsan son konakçı olduğundan vektör aracılığıyla kişiden kişiye bulaş gözlenmez. Anneden çocuğa, plasenta ve anne sütü yoluyla geçiş gösteren çalışmalar bulunmaktadır.​3​ Bazı çalışmalarda organ nakli ve kan transfüzyonu sonrasında bulaş bildirilmiş.​4,5​ Batı Nil Virüsünün Yaşam Döngüsü PATOFİZYOLOJİ WN, Flavivirüs cinsi Flaviviridae ailesinden tek sarmallı RNA virüsüdür. Sivrisinek, viral yükünü konakçıya tükürüğü vasıtasıyla bulaştırır. WN virüsünün subkutan inokülasyonu takiben yayılımı üç fazda gerçekleşir. Erken fazda, dermal dendritik hücrelerde ve keratinositlerde viral replikasyonu gerçekleşir. Bu fazı, viseral organ yayılım fazı ve merkezi sinir sistemi fazı takip eder.​6​ KLİNİK Batı Nil (WN) virüsü ile enfekte olmuş kişilerin çoğu asemptomatiktir; semptomlar enfekte hastaların sadece yüzde 20 ila 40'ında görülür. Enfeksiyon için tipik inkübasyon periyodu 2 ila 14 gün arasında değişirken, immünsuprese konaklarda daha uzun kuluçka periyotları gözlemlenmiştir. Hastalık ani başlangıçlı ateş, baş ağrısı, halsizlik, sırt ağrısı, miyalji ve iştahsızlık ile karakterizedir. Gözlerde ağrı, farenjit, bulantı, kusma, ishal ve karın ağrısı da görülebilir. Tipik semptomlar 3-10 gün arası sürerken, şikayetlerinin 10 günden daha fazla sürdüğü vakalar da literatürde bildirilmiştir.​7​ Hastaların %25-50 sinde, bir haftadan kısa süren, göğüste, sırtta ve kollarda gözlenen makülopapüler karakterde, bazen kaşıntının da eşlik ettiği döküntü görülebilir.​8,9​ Batı Nil virüsü enfeksiyonu ile ilişkili yaygın makülopapüler döküntü​9​ WN virüsü nöroinvaziv hastalığı, ateşin eşlik ettiği, menenjit, ensefalit, felç gibi hastalık paternleri ile kendini gösterebilir. Ensefalit, ileri yaş gruplarında menenjitten daha sık gözlenirken, menenjit çocuklarda daha sık görülür. Nöroinvaziv hastalık rapor edilen grupta ölüm oranı yaklaşık yüzde 10 olarak bildirilmiş. Ölüm için risk faktörleri arasında; ileri yaş, erkek cinsiyet, şiddetli kas güçsüzlüğünun eşlik ettiği ensefalit, bilinç değişikliği,

There is something beautiful about intelligence; it reveals how much we can become when we put ourselves to the task of searching and asking the right question.I am always fascinated by knowledge because our becoming, being, and living all rise and fall on the back of what we know. All of these begin with our intellect, the sum of our cognitive facilities, and the capacity for reasoning. This is where light comes to our mind, we develop, and our external world becomes a recipient of our realities.On this episode of the Word Café Podcast, I am honored to have someone who has embraced her intelligence as a gift and built a future.  Her name is Dr Nwamaka AkpodieteDr. Nwamaka Akpodiete is a post-doctoral research associate in vector biology with Target malaria, based at Keele University, United Kingdom. She conducts molecular ecological studies to understand the population dynamics and ecology of the African malaria mosquito Anopheles gambiae. Additionally, she provides support and training in molecular ecology, ecological statistics, and scientific writing at African partner institutions. Nwamaka has a 12-year of work experience in Higher Education involving teaching, mentoring, laboratory and field research, project supervision, and related administrative roles.   Nwamaka has a broad-based undergraduate and postgraduate education and research training in biology, biochemistry, molecular biology techniques, next-generation sequencing, entomology, zoology, and environmental sciences. Her BSc (Animal and Environmental Biology) research project was on the ecological dynamics of soil microarthropods about hydrocarbon pollution. She identified some bioindicators of soil pollution and microarthropod species indicative of soil recovery. This interest in environmental health led to an MSc in Environmental Quality Management. Nwamaka's MSc project was on the dipteran larvae in polluted water bodies in Port Harcourt, Rivers State, Nigeria. The project linked disease vectors such as Anopheles gambiae s.l. and Culex quinquefasciatus to indiscriminate waste disposal in Port Harcourt City, Nigeria. She also holds an MSc in Entomology and Pest Management from the University of Port Harcourt.  Her research interest in public and environmental health culminated in a Ph.D. in Entomology at Keele University, United Kingdom. Her Ph.D. research was focused on the evolutionary larval divergence in Anopheles gambiae s.l. About rice field domestication in Africa and improvement of An. gambiae s.l. Mass-rearing protocols for release. She also evaluated the use of zeolite in mosquito rearing and the characterization of microbial communities in the insectary via 16S rRNA gene sequencing. The study revealed ecological consequences of environmental manipulation, which has resulted in the speciation event in the malaria vector An. coluzzii, resulting in the year-round transmission of malaria and increased urban malaria. The findings from her Ph.D. research are relevant for malaria vector control, irrigated agricultural and urbanization policy reevaluation, and improvement of sterile insect techniques and gene drive protocols.  Nwamaka is actively involved in malaria campaigns@Zeromalaria to eradicate malaria in Africa.Support the show

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.09.26.509539v1?rss=1 Authors: Lu, W., LEAL, W. S., Brisco, K. K., An, S., Cornel, A. J. Abstract: The cornerstone of the reverse chemical ecology approach is the identification of odorant receptors (OR) sensitive to compounds in a large panel of odorants. In this approach, we de-orphanize ORs and, subsequently, measure behaviors elicited by these semiochemicals. After that, we evaluate behaviorally active compounds for applications in insect vector management. Intriguingly, multiple ORs encoded by genes highly expressed in mosquito antennae do not respond to any test odorant. One such case is CquiOR125 from the southern house mosquito, Culex quinquefasciatus Say. To better understand CquiOR125 role in Culex mosquito olfaction, we have cloned a CquiOR125 orthologue in the genome of the yellow fever mosquito, Aedes aegypti (L.), AaegOR11. Unlike the unresponsive nature of the orthologue in Cx. quinquefasciatus, oocytes co-expressing AaegOR11 and AaegOrco elicited robust responses when challenged with fenchone, 2,3-dimethylphenol, 3,4-dimethylphenol, 4-methycyclohexanol, and acetophenone. AlphaFold models showed that AaegOR11 and CquiOR125 share structural homolog cores with MhraOR5, the only insect OR structure (PDB: 7LID) elucidated to date. Interestingly, AaegOR11 responded strongly and equally to (+)- and (-)-fenchone, with no chiral discrimination. Contrary to reports in the literature, fenchone did not show any repellency activity against Ae. aegypti or Cx. quinquefasciatus. Laboratory and field tests did not show significant increases in egg captures in cups filled with fenchone solutions compared to control cups. The second most potent ligand, 2,3-dimethylphenol, showed repellency activity stronger than that elicited by DEET at the same dose. We, therefore, concluded that AaegOR11 is a mosquito repellent sensor. It is feasible that CquiOR125 responds to repellents that remain elusive. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Gene drives: why the wait?, published by Metacelsus on September 19, 2022 on LessWrong. (Crossposted from my Substack) If you've been following biology news over the last few years, you might have heard of an interesting concept called a “gene drive”. The overall idea is to engineer a genetic allele that transmits itself to all offspring of a sexually reproducing organism, instead of being inherited by 50% as usual. This allele can also perform some other biological function (a relevant example is causing female sterility). A gene drive spreads through a population. From Esvelt et al. 2014 (CC-BY) In multiple trials, modern CRISPR-based gene drives have shown high efficacy in spreading through populations of caged Anopheles mosquitoes and completely suppressing their reproduction. Since Anopheles mosquitoes are the only ones that transmit malaria, causing their extinction would directly save hundreds of thousands of lives per year. Similar gene drives targeted to other types of mosquitoes (Aedes, Culex, etc.) could also eliminate diseases such as dengue fever, Zika virus, and West Nile virus. However, in spite of promising laboratory trials, gene drives have not yet been deployed in the wild. But why not? History of gene drives Although the technology to build effective gene drives did not exist until recently, the idea has been around for a while. In fact, gene drives occur naturally. Some well-known examples are transposons in flies, homing endonucleases in algae, and segregation distorters in mice. The idea of engineering a site-specific nuclease as a gene drive was developed as early as 2003, and in the decade that followed there were several efforts to develop these, with the labs of Austin Burt and Andrea Crisanti taking a lead role. These early systems showed some biased inheritance, but were not stable for more than a few generations. The advent of CRISPR as a gene editing system opened up a new opportunity. A paper in 2014 by Kevin Esvelt and co-workers proposed Cas9 as a nuclease for a gene drive, with several properties making it ideal for the task. It lacks repetitive sequences that caused problems with earlier gene drives using zinc-finger nucleases or TALENs. It has a very high efficiency of cutting. It is easy to target a new site by simply changing the guide RNA. Several nearby sites could be targeted at once, using different guide RNAs. From Esvelt et al. 2014 (CC-BY) CRISPR-based gene drives quickly gained popularity in the field, and by 2018 the Crisanti lab had demonstrated a working gene drive that could efficiently suppress populations of Anopheles gambiae by targeting an exon of the doublesex gene required for female development. At the time this was announced, I was studying at the University of Cambridge, and attended a public lecture by Prof. Crisanti about his lab's work. The overall mood in the room was almost euphoric: here was a technology that could save millions of lives, the best thing since Borlaug's wheat! Since that lecture, about 2 million people, mostly children in Africa, have died of malaria. Gene drive research has not stood still: the Crisanti lab tested their doublesex drive in larger cages of mosquitoes, and it again completely eliminated the populations. But given the millions of lives at stake, what's taking so long for this gene drive to be released? See also: the battle against malaria in Africa has stalled Why the wait? There are two good arguments against the immediate release of gene drives to eliminate mosquitoes. First, nuclease gene drives have the possibility of generating resistant alleles, making future gene drives not work against the same target. Therefore, it's important to get it right the first time, otherwise the potential of gene drives could be wasted. The goal of the large cage trials I mentioned earli...

Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Gene drives: why the wait?, published by Metacelsus on September 19, 2022 on LessWrong. (Crossposted from my Substack) If you've been following biology news over the last few years, you might have heard of an interesting concept called a “gene drive”. The overall idea is to engineer a genetic allele that transmits itself to all offspring of a sexually reproducing organism, instead of being inherited by 50% as usual. This allele can also perform some other biological function (a relevant example is causing female sterility). A gene drive spreads through a population. From Esvelt et al. 2014 (CC-BY) In multiple trials, modern CRISPR-based gene drives have shown high efficacy in spreading through populations of caged Anopheles mosquitoes and completely suppressing their reproduction. Since Anopheles mosquitoes are the only ones that transmit malaria, causing their extinction would directly save hundreds of thousands of lives per year. Similar gene drives targeted to other types of mosquitoes (Aedes, Culex, etc.) could also eliminate diseases such as dengue fever, Zika virus, and West Nile virus. However, in spite of promising laboratory trials, gene drives have not yet been deployed in the wild. But why not? History of gene drives Although the technology to build effective gene drives did not exist until recently, the idea has been around for a while. In fact, gene drives occur naturally. Some well-known examples are transposons in flies, homing endonucleases in algae, and segregation distorters in mice. The idea of engineering a site-specific nuclease as a gene drive was developed as early as 2003, and in the decade that followed there were several efforts to develop these, with the labs of Austin Burt and Andrea Crisanti taking a lead role. These early systems showed some biased inheritance, but were not stable for more than a few generations. The advent of CRISPR as a gene editing system opened up a new opportunity. A paper in 2014 by Kevin Esvelt and co-workers proposed Cas9 as a nuclease for a gene drive, with several properties making it ideal for the task. It lacks repetitive sequences that caused problems with earlier gene drives using zinc-finger nucleases or TALENs. It has a very high efficiency of cutting. It is easy to target a new site by simply changing the guide RNA. Several nearby sites could be targeted at once, using different guide RNAs. From Esvelt et al. 2014 (CC-BY) CRISPR-based gene drives quickly gained popularity in the field, and by 2018 the Crisanti lab had demonstrated a working gene drive that could efficiently suppress populations of Anopheles gambiae by targeting an exon of the doublesex gene required for female development. At the time this was announced, I was studying at the University of Cambridge, and attended a public lecture by Prof. Crisanti about his lab's work. The overall mood in the room was almost euphoric: here was a technology that could save millions of lives, the best thing since Borlaug's wheat! Since that lecture, about 2 million people, mostly children in Africa, have died of malaria. Gene drive research has not stood still: the Crisanti lab tested their doublesex drive in larger cages of mosquitoes, and it again completely eliminated the populations. But given the millions of lives at stake, what's taking so long for this gene drive to be released? See also: the battle against malaria in Africa has stalled Why the wait? There are two good arguments against the immediate release of gene drives to eliminate mosquitoes. First, nuclease gene drives have the possibility of generating resistant alleles, making future gene drives not work against the same target. Therefore, it's important to get it right the first time, otherwise the potential of gene drives could be wasted. The goal of the large cage trials I mentioned earli...

英语新闻∣南方蚊子疑似变少，网友：终于连蚊子都要被热死了？Have you noticed feweritchy, red bumps on your skin this summer? It's probably due to the hot, dry weather this summer.今年夏天，瘙痒红肿的蚊子包少了很多，原因就是今年夏天炎热干燥的天气。The right amount of rain at the right time is needed for mosquitoes to breed because it lays eggs on the surface ofstagnantwater.蚊子的繁殖需要合适的环境和适当的降雨量，因为蚊子会在死水表面产卵。Individuals reared at higher temperatures may develop more rapidly compared to lower temperatures, but adults tend to be smaller with reduced fitness given that size is often positively related tofecundity.在较高温度下长大的个体可能比在较低温度下成长得更快，但成年个体往往体型较小，适合度降低，因为体型通常与繁殖能力呈正相关。As temperatures climb higher, mosquito activity can decline. Mosquitoes will bite less when it becomes excessively hot.随着气温上升，蚊子的活动会减少。天气过于炎热时，蚊子叮咬的次数就会减少。Higher temperatures also make any diseases they carry more active and hence moretransmissible. So when mosquitoes are around, a cool spell following very hot temperatures could be ripe for mosquito borne diseases, as highly infectious mosquitoes increase their biting activity.虽然高温不利于蚊子生存，却有利于蚊子携带的病毒传播。只要一息尚存，高温之后的凉爽期，很可能就成了蚊子传播疾病的最佳时机。Mosquito speciesthat transmit diseases mainly include Culex, Aedes, and Anopheles. Thediseases includemalaria, filariasis, and dengue.主要有三类蚊子会传播疾病：库蚊、伊蚊和按蚊，传播的疾病包括疟疾、丝虫病、和登革热等。Beekeepers in European reported unusual deaths of honeybee queens, drones and small colonies. Drones, which are the reproductive males, spontaneously ejaculate when they die from stress.最近连月高温，许多欧洲国家出现蜜蜂连续死亡，而且死去的大部分是雄蜂。雄蜂对温度十分敏感，高温的压力下，雄蜂的自然反应是射精，然后死去。Worryingly, male fertility likely begins to decline well before the drones die. This means that after a heat wave, new queens—the reproductive females—will have fewer opportunities to mate. Colonies headed by poorly mated queens are more likely to collapse, and this could pose problems for farmers who rely on honeybees topollinatetheir crops.就算雄蜂熬过了高温，生育能力也会受损。等到热浪过去，蜂后与雄蜂的交配机会减少，可能会导致整个蜂群的崩溃。依赖蜜蜂授粉的植物也会遭殃，其中有不少是人类赖以生存的农作物。To the end, the decline of mosquitoes is also a wake-up call from nature. If left unchecked, climate change and environmental degradation will eventually affect human beings.说到底，蚊子变少，也是大自然对我们敲响的警钟。如果放任气候变暖、环境恶化，终有一天会波及人类自身。itchy英[ˈɪtʃi]美[ˈɪtʃi]adj.（使）发痒的stagnant 英[ˈstæɡnənt]美[ˈstæɡnənt]adj. 不流动的，停滞的fecundity英[fɪ'kʌndətɪ]美[fɪˈkʌndətɪ]n. 多产； 肥沃； 产卵力transmissible英[træns'mɪsəbl]美[træns'mɪsəbəl]adj. 可传送的，可遗传的pollinate英[ˈpɒləneɪt]美[ˈpɑləneɪt]vt. 给…传授花粉

A seguito della segnalazione di casi di West Nile virus in Veneto, la Regione ha avviato una campagna informativa in collaborazione con i Comuni e le Aulss al fine di prevenire la diffusione dell'infezione trasmessa dalle zanzare “Culex”. Per evitare le punture si raccomanda di indossare all'aperto vestiti di colore chiaro, leggeri e coprenti e di utilizzare dei repellenti da applicare sulla pelle. Le raccomandazioni complete sono disponibili nel sito della Regione del Veneto

Controlling a mosquito population in South Florida can be a daunting task. On today's edition of Pestgeek Podcast, we discuss how to deal with mosquito populations in South Florida. On this property we have approached mosquito control with a variety of products such as Catchmaster Final Feed Mosquito Bait which controls Aedes and Culex mosquitoes.… The post Dealing With Mosquito Population in South Florida Using Inzecto Mosquito Traps appeared first on Pest Geek Pest Control Podcast .

Genetic Engineering and Society Center GES Colloquium - Tuesdays 12-1PM (via Zoom) NC State University | http://go.ncsu.edu/ges-colloquium GES Mediasite - See videos, full abstracts, speaker bios, and slides https://go.ncsu.edu/ges-mediasite Twitter - https://twitter.com/GESCenterNCSU The missing ecology in gene drive research Dr. Sumit Dhole, Research Scholar in Mathematical Biology, NC State LinkedIn | Google Scholar A discussion about some of the ecological aspects of population suppression using gene drives, and areas that need more research. Abstract Gene drives are rapidly emerging as a potential tool for controlling populations of disease vectors, invasive species and agricultural pests. The molecular research to create new and improved gene drives based on the CRISPR technology has progressed rapidly. While this research has been encouraging from the perspective of developing these tools, there remain large gaps in our understanding of how natural populations would respond to the release of gene drives. Dr. Dhole will discuss some of the ecological processes that will play an important role and that need more research in natural pest populations. Related links: Rajagopalan PK, Curtis CF, Brooks GD, Menon PK. The density dependence of larval mortality of Culex pipiens fatigans in an urban situation and prediction of its effects on genetic control operations. Indian J Med Res. 1977. North, A., Burt, A. & Godfray, H. Modelling the potential of genetic control of malaria mosquitoes at national scale. BMC Biol 17, 26 (2019). https://doi.org/10.1186/s12915-019-0645-5 James J Bull, Christopher H Remien, Stephen M Krone, Gene-drive-mediated extinction is thwarted by population structure and evolution of sib mating. Evolution, Medicine, and Public Health, Volume 2019, Issue 1, 2019, Pages 66–81, https://doi.org/10.1093/emph/eoz014 Speaker Bio Dr. Sumit Dhole is an evolutionary ecologist who uses mathematical models to study how genes can spread through natural populations. For the past few years at NC State his focus has been on understanding how synthetic gene drives might behave if introduced into natural populations. While gene drives, which are highly invasive genetic constructs, may provide a solution for rapid and species-specific management of disease vectors and agricultural pests, a major concern is the potential of their unchecked spread to non-target populations. Through his work, Sumit tries to understand what factors and design features may allow synthetic gene drives to spread in safe, contained manners. GES Center - Integrating scientific knowledge & diverse public values in shaping the futures of biotechnology. Find out more at https://ges-center-lectures-ncsu.pinecast.co

Aedes Aegypti Gelecekte 2020'li yıllar, yaşanan COVID-19 Pandemisi, depremler, ekonomik krizler, siyasal ve politik skandallar derken herhalde kriz yılları olarak hatırlanacak. Ancak tüm bunların yanında küçük ama rahatsız edici bir felaket daha vardı. Yaz kış demeden amansız sivrisinek saldırıları. Üstelik alışageldiğimiz kahverengi Culex'lerin yanında nispeten yeni bir tür olan siyah ve benekli Aedes saldırıları sanırım hepimizi canımızdan bezdirdi. Skeeter Sendromu Nedir? Özellikle kıyı kesimleri başta olmak üzere evlerde, balkon ve bahçelerde açık havayı zehreden nispeten yeni bir tür olan Aedes sivrisineklerin saldırısına maruz kaldık. Bir türlü görülmeyen ama vızıldayan açgözlü saldırgan sivrisinekler hortumunu (proboskis) uzatıp derileri deldi ve kanları hunharca emdi; ardında bıraktığı sıra dışı büyüklükteki papular ürtikeryel lezyonlar kaşınmaya başlayınca farkına vardık. Eğer sivrisinek sokması sonrası ciltte anormal büyüklükte şişlikler oluşuyor bazen ateş buna eşlik ediyor ama kaşıntı-kızarıklık dışında başka bulgu yoksa işte buna Skeeter Sendromu deniyor.​1​ Normalde sivrisineklerin salgılarındaki bazı proteinlere karşı çoğu insanın derisinde basit bir alerjik reaksiyon gelişir; genelde bu durum lokal küçük bir şişlik ve kızarıklık ile sınırlı kalırken bazı insanlarda biraz abartılı bir reaksiyon olabilir. Bu kaşıntılı lezyonlar tek büyük bir kabartı olabileceği gibi birçok küçük kabartı olarak da görülebilir. Skeeter Sendromu sivrisinek sokmasına bağlı abartılı alerjik reaksiyondur​1​ Skeeter Sendromunun bilinen hayati riski ve klinik bir önemi olmadığı gibi spesifik bir tedavisi de yoktur. Çok rahatsızlık verirse topikal ya da oral antihistaminik ilaçlar kullanılabilir. Skeeter Sendromuna karşı tek çare sivrisinek sokmalarından korunmaktır. Sivrisinek yaşam döngüsü Sivrisinek sokmasından korunmak için de sivrisineğin yaşam döngüsünü, neden ve nasıl soktuğunu bilmek gerekiyor:   Sivrisineğin yaşamında yaklaşık iki hafta kadar süren dört evre vardır: durgun suda geçen (i) yumurta, (ii) larva ve (iii) pupa evresi ve karada geçen (iv) erişkin evresi. Suda geçen evreler en kritik süreçtir; sivrisinek bu süreçleri yaşam alanımızın 50-100 metre yarıçapı bir alanda eski saksılar, lastikler teneke kutular, çukurlar vb toplanan her türlü durgun su birikintisinde geçirir. Sonrasında erişkin hale gelen dişi sivrisinek yumurtalarını olgunlaştırabilmek için demire ihtiyaç duyar ve bu demir ihtiyacını memeli kanındaki Hemoglobin ve Transferrin proteinlerinden elde eder.​​2​ Dişi sivrisinek proboskis denen evrimleşmiş ağız ve burun ortak hortumunun yapısında gelişmiş koku reseptörlerini kullanarak avlarının kokusunu karanlıkta bile bulabilir. Özellikle parfüm, ter asiti ve nefesteki karbondioksit kokuları sivrisineği çeker; bu şekilde sivrisinek cilde yaklaşır ve konar. Sivrisinek proboskisi ile cildi delip kılcal kan damarlara ulaşır. Bu delme ve emme işlemi olağanüstü gelişmiş bir doğal biyomikroelektromekanik sistemdir.​3​ Acil serviste damar yolu açarken kullandığımız kateter mantığı ile sivrisinek proboskisin sivri ucu ile cildi deler, sert kısmı geri çekerken burna benzer esnek kısım kılcal damarın içine yerleştirir. Bu da gösteriyorki sivrisinekler doğanın minik muazzam damaryolu açıcıları, canlı kateterlerdir ve damar bulmada hiç başarısız olmazlar. Delme ve emme işleminde ağız ve burun parçalarının ortak çalışması kan emeceği kişiyi seçmesinde o kişinin yaydığı kokunun önemli olduğunu göstermektedir. Sivrisinekler koklar, görür ve işitir; yaklaşık 50 metre öteden havadaki karbondioksit kokusunu alır, kokuyu takip eder 5-10 metre uzaktan insanı görebilir ve yaklaşır ve son 20-30 cm de ciltten yükselen termal ısı buharını ve kokuyu algılar. Artık geriye sadece cildi delip kanı emmek kalır. Sonuçta artık sivrisinek soktuğunda “Bakın ne kadar kabardım!” demektense “Sanırım ben Skeeter Sendromu oldum” demek belki kaşıntınızı azaltmasa da havanızı artırabilir.

El virus del Nilo Occidental es un flavivirus emergente transmitido generalmente por mosquitos del género Culex que se mantiene en un ciclo de vida en el que los pájaros hacen las veces de principal reservorio. Los caballos y los humanos también son susceptibles de infectarse y, en los casos más extremos, acaban desarrollando complicaciones de tipo neurológico. Un estudio acaba de determinar que casi el 20 por ciento de las aves silvestres de la región tienen anticuerpos frente a este patógeno, comentamos este trabajo y sus implicaciones con Eva Frontera, investigadora de la Facultad de Veterinaria de la UEx.

आज FYI के इस एपिसोड में साहिबा ख़ान बात करेंगी उन मच्छरों की जिन्होंने आपकी रात की नींद मुहाल कर के रखी है। मगर क्या ये नार्मल मच्छर हैं जो गर्मी में आ के चले जाते हैं  या फिर इनसे है ज़्यादा ख़तरा? क्या ये मच्छर गंभीर बीमारी फैला सकते हैं? और क्यों बढ़ते जा रहे हैं ये हमारे आस-पास।  इन सभी सवालों का जवाब देंगी साहिबा आज के FYI में

Our Media Partner - https://www.rpgfan.com/ Check out our Discord: https://discord.gg/C3zAnQu Twitter: https://twitter.com/PhoenixEdgeRPG 01:50 - Overall Impressions 08:07 - Development History / Nintendo & Square Relationship 19:30 - Graphics/Art Style 23:53 - Isometric Platforming & More In-Depth Graphics Discussion 37:48 - Bowser as an Ally / Thoughts on Premise 52:19 - World Building 58:40 - Dungeon Design 01:01:52 - Recognizable Mario Elements Inserted into Game 01:09:50 - Mario RPG is a Comedy 01:20:15 - Ted Woolsey Localization 01:25:12 - Main Characters 01:39:38 - Culex 01:45:05 - Mini-Games 01:49:56 - Combat 02:03:35 - Soundtrack 02:15:40 - Discord Questions/Comments

Nevím jak vy, ale já mám v letošním létě na chalupě dva úhlavní nepřátele. Culex pipiens a Arion vulgaris.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.26.062919v1?rss=1 Authors: Kythreoti, G., Sdralia, N., Tsitoura, P., Papachristos, D. P., Michaelakis, A., Karras, V., Ruel, D. M., Yakir, E., Bohbot, J. D., Schulz, S., Iatrou, K. Abstract: Odorant-dependent behaviors in insects are triggered by the binding of odorant ligands to the variable subunits of heteromeric olfactory receptors. Previous studies have shown, however, that specific odor binding to ORco, the common subunit of odorant receptor heteromers, may alter allosterically olfactory receptor function and affect profoundly subsequent behavioral responses. Here we report on the identification of several antagonists of the odorant receptor co-receptor of the African malaria vector Anopheles gambiae, AgamORco, in a small collection of natural volatile organic compounds (VOCs) using a relevant insect cell-based screening platform. Because some of the identified antagonists were previously shown to strongly repel Anopheles and Culex mosquitoes, here we examined the bioactivities of the identified antagonists against Aedes, the third major genus of the Culicidae family. The tested antagonists were found to inhibit the function of Ae. aegypti ORco ex vivo and repel Asian tiger, Ae. albopictus, adult mosquitoes. Specific antagonist binary mixtures elicited higher repellency than single antagonists. Binding competition assays suggested antagonist binding to distinct ORco sites as a likely cause for the enhanced repellence of the blends. These findings demonstrate that a simple screening assay may be used for the identification of allosteric modifiers of olfactory-driven behaviors capable of providing enhanced indoor and outdoor protection against multiple mosquito borne infectious diseases. Copy rights belong to original authors. Visit the link for more info

How do arboviruses evolve as they pass between different hosts? Greg Ebel discusses his research on West Nile virus evolution and what it means for viral diversity. He also talks about using mosquitos’ most recent blood meal to survey human health in a process called xenosurveillance. Julie’s Biggest Takeaways: Mosquitoes and other arthropods have limited means of immune defense against infection. One major defense mechanism is RNA interference (RNAi). RNAi uses pieces of the West Nile viral genome to select against the viral genome, which helps select for broadly diverse viral sequences. The more rare a viral genotype, the more likely it is to escape negative selection inside the mosquito host, allowing this viral sequence to increase in frequency.  West Nile virus passes largely between birds and mosquitos. Culex mosquitos tend to prefer birds, and this leads to an enzootic cycle for the virus passing between birds and mosquitos. The viral life cycle inside the mosquito has several important steps:  The virus first enters as part of the mosquito blood meal.  The virus infects epithelial cells of the mosquito midgut. After 3-5 days, the virus leaves the midgut (midgut escape) to enter the mosquito hemolymph. In the next mosquito blood meal, virus is expelled with saliva, which has anticoagulant activity. West Nile virus selection undergoes cycles of selection as it passes from vertebrates (mostly birds) to invertebrates (mosquitos): In vertebrates, the virus must escape to cause viremia in a short period of time for replication to occur before the immune system recognizes and eliminates the virus. This leads to purifying selection, or elimination of amino acid variation that decreases viral protein function. In mosquitos, the virus spends several days in the midgut epithelial cells and then hemolymph, leading to a longer selection time. This leads to more viral diversity in the mosquito host. RNAi further drives population diversity. Through stochasticity, a single viral population will often come to dominate a single infected mosquito. How do scientists know which virus replicates best? Competitive fitness tests measure which virus grows to a higher population in a given environment. A manipulated virus (one passaged in a mosquito or selectively mutated at distinct sequences) and its non-manipulated parent sequence are inoculated at known proportions, and given a certain amount of time to replicate. By measuring the final proportions, Greg and his team can determine which sequence was more fit in that given environment.  Xenosurveillance uses mosquitoes to detect a wide array of pathogens at clinically relevant levels. Testing began with in vitro blood-bag feeding, and was validated with studies in Liberia and Senegal. The microorganism sequences are so diverse that the information was used to identify novel human viruses. These studies also provide insight into mosquito feeding habits, which helps in disease modeling. Links for this Episode:  Greg Ebel Lab Website Rückert C. et al. Small RNA Responses of Culex Mosquitoes and Cell Lines during Acute and Persistent Virus Infection. Insect Biochemistry and Molecular Biology. 2019. Grubaugh N.D. et al. Mosquitoes Transmit Unique West Nile Virus Populations during Each Feeding Episode. Cell Reports. 2017. Grubaugh N.D. and Ebel G.D. Dynamics of West Nile Virus Evolution in Mosquito Vectors. Current Opinion in Virology. 2016. Fauver J.R. et al. Xenosurveillance Reflects Traditional Sampling Techniques for the Identification of Human Pathogens: A Comparative Study in West Africa. PLoS Neglected Tropical Diseases. 2018. Fauver J.R. The Use of Xenosurveillance to Detect Human Bacteria, Parasites, and Viruses in Mosquito Bloodmeals. American Journal of Tropical Medicine and Hygiene. 2017. Tracey McNamera: Canaries in the Coal Mine TEDxUCLA New York Times: Encephalitis Outbreak Teaches an Old Lesson. 1999. ASM Article: The One Health of Animals, Humans, and Our Planet: It’s All Microbially Connected    

Jim Cornette trends, John beat Smithy but not Culex, ebay Hasbro cancellations, Chris and John dissect the QB situation to see who is better/worse than Dak Prescott. Chris forgot the name of the episode again.

[00:00:02] Hey welcome back. Welcome back to another edition of the pestgeek podcast. I am your host Frank Hernandez and we're gonna be discussing culex mosquitoes. That's right. It's mosquito season soon as those temperatures rise above 70 degrees they start coming out and they start populating and we're going to be covering culex mosquitoes… The post Culex mosquitoes quinquefasciatus and pipiens the hybrid is pipiens-molestus. appeared first on Pest Geek Pest Control Podcast .

Super Mario RPG Part 4!  Check out our new, limited time only store: http://coachsassistant.gtmsportswear.com/squareroots We start off with 65 Rules For Dating My Gay Friend John, the terrible 6 Doors of Disappointment, the insane boss rush that is the final stage, discussing the physiology of Exor, casting a new hypothetical Super Mario Brothers movie, we trade Culex strategies, Matthew relies on Geno Flash to win the game, and we try to figure out who some of these late game bosses are. There's final thoughts on the game with no set rating system, and most importantly we break down the government structure and long-con of the Mushroom Kingdom. Spoiler: Mario is a useful idiot. This week: We finish the game! Next week: We get to the Gummi Ship in Kingdom Hearts 1! Twitter: @squarerootspod Facebook: https://www.facebook.com/groups/486022898258197/ Email: squarerootspodcast (at) gmail (dort) com Our theme music is by Mykal Williams, check out his Youtube here: https://www.youtube.com/channel/UCNYPoyecyVkXzg4D3Pq5mKw  His Soundcloud is here: https://soundcloud.com/mykalwilliams

Olá, Pessoas! Neste episódio descobrimos o Nicho do Msc. Marco Marchi! Descubra um pouco mais sobre os mosquitos estéreis da fazendola do Tiri!Faça o Download do episódio em: http://bit.ly/onicho-06 Assine nosso feed e receba todos os episódios automaticamente: http://feeds.feedburner.com/ONichoou assine no iTunes: itpc://feeds.feedburner.com/ONicho Curta nossa página no Facebook: http://facebook.com/onichopodcastSe inscreva em nosso canal do Youtube: https://www.youtube.com/channel/UC6GSsct7E6UhOev75tZHpyQ Referência do trabalho:Petersen, Vivian, Marchi, Marco Jacometto, Natal, Delsio, Marrelli, Mauro Toledo, Barbosa, Admilson Clayton, & Suesdek, Lincoln. (2016). Assessment of the correlation between wing size and body weight in captive Culex quinquefasciatus. Revista da Sociedade Brasileira de Medicina Tropical, 49(4), 508-511. https://dx.doi.org/10.1590/0037-8682-0039-2016 Links comentados no programa: - IV Jornada das Licenciaturas em Ciências Biológicas (UFSC)https://jolibio2016.wordpress.com/ - Sitehttps://www.facebook.com/events/204993983265926 - Evento Facebook- Financiamento Coletivo para a pesquisa de campo do Caiohttp://www.pterulaceae.com Músicas do Episódio por:Kevin MacLeod (incompetech.com), Royalty Free Music from Bensound (www.bensound.com) & music by audionautix.comLicensed under Creative Commons: By Attribution 3.0 License http://creativecommons.org/licenses/by/3.0/ Arte da Vitrine por Mari Doria ‪#‎onicho‬ ‪#‎podcast

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit From the twiVivants, follow up on FluMist and Zoster vaccines, Zika virus update, and isolation of a multicomponent animal virus from mosquitoes.   Become a patron of TWiV! Links for this episode FluMist problem (FDA) DA Henderson obituary (NY Times) DA Henderson, smallpox eradicator (TWiV Special) Efficacy of VZV vaccine (Ther Adv Vaccines) Zika virus burden, Puerto Rico (JAMA) Zika virus in Miami Beach (STAT) Congenital brain anomalies and Zika virus (Radiology) Congenital Zika syndrome with arthrogryposis (BMJ) Multicomponent animal virus from mosquitoes (Cell Host Microbe) Breaking rules of infection (NPR) Image credit Letters read on TWiV 404 This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completel free if you sign up at curiositystream.com/microbe and use the promo code MICROBE. This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100. Weekly Science Picks Alan - Sally Le PageDickson - Comfortably Numb by Jamie Dupuis Rich -  Learned HelplessnessVincent - Virus by Marilyn Roossinck Listener Picks OneTime - The Stranglers - Old CodgerSteve - A Poem About Pronunciation Send your virology questions and comments to twiv@microbe.tv

Episode 4: Homeopathy in Japan The Present, an interview with Torako Yui As a bridge out of the homeoprophylaxis theme, Torako Yui shares her extraordinary journey to, and with, homeopathy. I was introduced to Torako through my interview with Kate Birch. Torako has been very active with homeoprophylaxis and offering Hp kits to families in Japan. But her work reaches far and wide. Recognizing the blocks to health in diet and lifestyle, Torako has started organic farms as well as developed organic body care products.  The Past, 1931 The Management of the Chronic Case and Removal of Obstacles to Recovery: a paper presented by Eugene Underhill at the Bureau of Homeopathic Philosophy, June 1931 I read the words of E. Underhill, describing the necessary task of removing obstacles from cure so that our patients *may* truly be cured.  The Future, Mosquitoes as vectors of viruses Thinking about the theme of Japan, I looked up Japanese Encephalitis to get a bit more acquainted with the disease. I followed my questions of connections and diversions with the current outbreaks of Zika virus (different mosquito), the Culex mosquito, proving, and malaria.    Links Torako's website (beautiful!) Torako article, hpathy.com Torako article, interhomeopathy.com Lou Klein's Zhomeo (webinars)    

Background Current strategic plans for malaria control in Ghana include the attainment of 80% of the general population sleeping under insecticide treated materials (ITM) by 2015. This coverage may not be attained if there is non-compliance in the use of bed nets. Failure of ITM to protect users from nuisance mosquitoes, particularly Culex mosquitoes has been cited as one of the major threats to the sustained use of ITM. A nationwide survey was therefore carried out to determine insecticide resistance status of Culex species and efficacy of ITM against them. Methods and materials Mosquito larvae were sampled from various land use and ecological settings and at different seasons. These were reared to adults and used for the various tests. In adults, insecticide susceptibility tests to eight insecticides as well as cone and tunnel bioassays were performed. Biochemical and molecular analyses were also conducted to determine the resistance mechanisms in the study populations. Results Culex quinquefasciatus and C. decens were the Culex species that were identified in the study area. DDT and deltamethrin resistances were evident across the country. A strong relationship between resistance status and urban size was observed in the study population (Pearson χ2 =48.2; df = 1; P

The outbreak of Schmallenberg disease amongst sheep and cattle on British farms has provided a powerful reminder of how novel infections can develop, spread and kill before the authorities have a chance to react. Scientists are still working hard to fully understand the virus and a vaccine is still some way off so what can we do to protect ourselves against future disease outbreaks? And how can we discover what diseases could be heading our way? Tom Heap heads to the Kent marshes in search of one of the potential carriers of nasty illnesses: Culex modestus. It's known to be a successful carrier of West Nile Virus - a paricularly nasty illness - and while the mosquito has been found on the marshes of Kent the disease has not made it's way to the UK yet. Costing The Earth also discovers the vital role social media could play in monitoring future epidemics. Intensive farming, international travel, global trade and climate change are all playing a role in changing the diseases we encounter. In 'Costing the Earth' Tom Heap asks what epidemics we should expect in the future and examines the readiness of government, the medical profession and the pharmaceutical industry. Producer: Martin Poyntz-Roberts.

On episode #73 of the podcast This Week in Virology, Vincent, Dickson, and Rich discuss multipotent progenitor bone marrow cells as a reservoir of HIV-1, integration of HHV-6 into telomeres, and dispersal of West Nile virus across the US by mosquitoes. Host links Vincent Racaniello, Dickson Despommier, and Rich Condit Links for this episode: HIV-1 infects multipotent progenitor cells HHV-6 genome integrates into telomeres A role for mosquito-mediated dispersal of West Nile virus across the US Using tobacco mosaic virus to produce synthetic photovoltaic cells (thanks Nissin!) Animation of HIV replication cycle (thanks Ilya!) Can computer viruses evolve? (thanks Norman!) Mumps outbreak in Israel (one and two) (thanks Ariel!) Bocavirus infections in children (thanks Tyler!) Weekly science picks: Dickson Whole-Genome Sequencing in a Patient with Charcot–Marie–Tooth Neuropathy (NEJM and NY Times) Rich Invisible Frontiers: The Race to Synthesize a Human Gene by Stephen Hall Vincent Conference on Retroviruses and Opportunistic Infections - videocasts