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Imran Mahmood discusses with Ivan six things which should be better known. Imran Mahmood is a criminal defence barrister with over thirty years' experience. His debut novel You Don't Know Me was longlisted for both the Theakston Crime Novel of the Year and the CWA Gold Dagger in 2017, and selected by Simon Mayo as a BBC Radio 2 Book Club choice in the same year. It was then adapted into a four-part BBC crime drama, airing on a prime-time BBC One slot in 2021, before being released internationally on Netflix the following year and becoming one of the platform's most streamed shows. His second novel, I Know What I Saw (2022) was named a Sunday Times Crime Novel of the Month and reached No. 2 on the Audible charts. Mahmood has written three screenplays and is a regular contributor to the Red Hot Chilli Writers podcast. His new novel is Finding Sophie, which is available at https://www.waterstones.com/book/finding-sophie/imran-mahmood/9781526647566 Sentencing for Crimes https://www.sentencingacademy.org.uk/wp-content/uploads/2024/02/Mandatory-Minimum-Sentences-Explainer.pdf The Deep and Lasting Power of Books https://medium.com/@ariszavitsanos/the-enduring-power-of-literature-why-it-matters-now-more-than-ever-42900c18e7b The Quran https://www.nybooks.com/online/2017/02/09/crafting-the-koran/ Manipulation by Politicians and Social Media Algorithms https://www.ox.ac.uk/news/2021-01-13-social-media-manipulation-political-actors-industrial-scale-problem-oxford-report Mycorrhizal Networks https://en.wikipedia.org/wiki/Mycorrhizal_network Turritopsis dohrnii https://thebiologist.rsb.org.uk/biologist-features/everlasting-life-the-immortal-jellyfish This podcast is powered by ZenCast.fm
Content Warning: Tod (außer im Audiorätsel :) Düstere Themensammlung: Wir besprechen einen wissenschaftlich-künstlerischen Film, der uns über Weltraumteleskope, kupferne Mumien und andere Körper in der Erde nachdenken lässt. In Martas Buchstabenkolumne geht es um (Un)sterblichkeit und was uns einige fantastische Tierwesen in der Hinsicht voraus haben. Außerdem geht uns der hypnotische Film 'I Saw the TV Glow' an die Nieren. Kapitelchen & Tracklist 0:00:00 sylken somers – please hold CC BY-NC-SA 0:03:33 Chan Sook Choi, qbit to adam 0:23:06 Grrrl Gang – Spunky! CC BY-NC-SA 0:25:11 I wie Immortalität 0:48:34 Sasha Paris-Carter – Royal Pigeon Claw CC BY-NC-SA 0:50:18 I wie Immortalität 2 1:08:13 banríon – departure party CC BY-NC-SA 1:11:58 Audiorätsel 1:20:11 Sue Lynch – These Lamps CC BY-NC-SA 1:25:28 I Saw The TV Glow 1:54:49 Submaureen – Rio CC BY-NC-SA Shownotes qbit to adam von Chan Sook Choi Videoraum bei der Berlinischen Galerie - dieser Link wird wahrscheinlich nutzlos werden chansookchoi.com Installationsansichten und ein bizarres 360°-Video von 2021 bei Kang Contemporary I wie Immortalität Hayflick-Limit, Antagonistische Pleiotropie, Süßwasserpolyp, Turritopsis dohrnii auf Wikipedia Audiorätsel Auflösung als Video! 37 Sekunden Auflösung als Foto Danke Kira! I Saw the TV Glow bei IMDb Interview mit Jane Schoenbrun und Analyse von Tasha Robinson bei Polygon Podcast-Tipp: Blank Check bespricht Twin Peaks: The Return (Ep 14–18) mit Jane Schoenbrun zu Gast Credits & Lizenz Cover: basierend auf Robert Fludd Metaphysik und Natur- und Kunstgeschichte beider Welten, nämlich des Makro- und des Mikrokosmos, 1617; Public Domain via Wikimedia Commons Flyer: basierend auf einem Bild aus Popular Science Monthly, Public Domain via Wikimedia Commons Diese Folge erscheint unter CC BY-NC-SA 3.0, d.h. unsere Inhalte gerne teilen, remixen, aber uns bitte erwähnen und ja kein Geld verdienen! Musik siehe jeweilige Lizenzen.
Elles sont 6 millions à mourir en nous chaque minute, 10 milliards chaque jour. Les cellules qui composent notre corps, nos tissus et nos organes sont en perpétuel renouvèlement, dans une auto-gestion presque parfaite. Un système de mort cellulaire programmée à plusieurs visages mais qui parfois bugge. Des cellules se transforment en tumeur, d'autres disparaissent, attaquées par leur propre système immunitaire. Et si la recherche médicale pouvait changer tout cela ? En plateau pour cette émission, notre invitée Sophie Barillé-Nion, chercheuse Inserm au Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes-Angers (CRCI2NA) Avec une chronique de Florian Martin, qui nous révèlera les secrets de l'immortalité des méduses, des vampires, et se demandera si les elfes du Seigneur des anneaux ne sont pas en réalité des requins. Cette émission est en partenariat avec le Muséum d'histoire naturelle de Nantes Métropole et son cycle de conférences : Sciences éton'Nantes.Une émission préparée et animée par Sophie Podevin, réalisée avec l'aide d'Adrien Podevin. Ressources : Le médicament Venetoclax sur le VIDAL Les différentes types de mort cellulaire programmé Ressource INSERM sur les télomères Morphological and ultrastructural analysis of Turritopsis nutricula during life cycle reversal Transcriptome Characterization of Reverse Development in Turritopsis dohrnii White shark genome reveals ancient elasmobranch adaptations associated with wound healing and the maintenance of genome stability
Dans le classement des animaux vivant le plus longtemps, les 5 premières places sont trustée par des animaux aquatiques:1- La méduse (Turritopsis nutricula) approche l'immortalité car, non seulement elle renouvelle ses cellules, mais elle peut retourner à un état larvaire en cas de stress.2- L'éponge (Anoxycalyx joubini) est en réalité non pas un animal mais une colonie de cellules vivant ensemble, pourrait vivre plus de 10000 ans. Chaque individu ne vit tout au plus que 10 ans mais la colonie se renouvelle en permanence.3 - La praire d'Islande (Arctica islandica) peut vivre plus de 500 ans. Un spécimen célèbre a été baptisé Ming, du nom de la dynastie au pouvoir en Chine lorsqu'il est né.4 - Le requin du Groenland (Somniosus microcephalus) est l'un des plus gros requins carnivores de la planète. Il détient le record de longévité chez les vertébrés: 500 ans.5- La baleine boréale (Balaena mysticetus) peut vivre jusqu'à 200 ans. C'est le record de longévité des mammifères._______
Er is een tijd van komen en een tijd van gaan. Iedereen gaat een keer. Behalve de Turritopsis nutricula kwal. Die kan zijn cellen vernieuwen, waardoor hij weer een schattig poliepje wordt.Nienke omarmt haar grijze haren en rimpels. Je moet er toch een keer aan. Behalve als je de naakte molrat bent. Die heeft sowieso geen haar. En wordt ook nog eens superoud. Ook krijgt hij geen kanker. Nienke doet een oproep aan alle onderzoekers: focus je op dit beestje!Mensen zijn niet de enige dieren die rouwen en begrafenissen houden. Mátyás heeft een mooi verhaal over olifanten die hun doden begraven.En 3 op reis presentator Dzifa Kusenuh vertelt in de rubriek Opgebiecht over een hondje dat ze op een markt in Ghana heeft gekocht. Het hondje kan het verhaal helaas niet navertellen.Abonneren?SpotifyApple PodcastsRSS Meer info:Alles over de podcastAlles over MatyasAlles over NienkeFeedback?Mail naar podcast@wwf.nl.
In this week's journey into the bizarre and extraordinary, join Kat and Jethro as they delve into the realms of immortality, paranormal history, ancient music, and cryptid mysteries.
Esta es una de las distopías más tratadas en cine y series de ficción. Incluso yo la he tratado alguna vez anteriormente con otro punto de vista, desde el punto de vista de la ciencia. Hoy, vamos a abordar el tema madurado desde un punto de vista filosófico para tratar esta distopía de lo que podría implicar vivir para siempre. ¿Es posible vivir para siempre? La idea de vivir para siempre ha fascinado a la humanidad desde tiempos inmemoriales. ¿Quién no querría disfrutar de la vida sin tener que preocuparse por el envejecimiento, las enfermedades y la muerte? Sin embargo, ¿es realmente posible alcanzar la inmortalidad? ¿Qué implicaciones tendría para la sociedad, la ética y el medio ambiente? En este artículo, exploraremos algunas de las posibles formas de vivir para siempre y sus ventajas y desventajas. La inmortalidad biológica Una forma de vivir para siempre sería lograr la inmortalidad biológica, es decir, detener o revertir el proceso de envejecimiento celular. Algunos organismos, como las medusas Turritopsis dohrnii o las hidras, son capaces de regenerar sus tejidos y evitar el deterioro asociado a la edad. ¿Podría la ciencia aplicar este mecanismo a los seres humanos? Algunos científicos creen que sí, y están investigando diferentes estrategias para lograrlo. Por ejemplo, el biogerontólogo Aubrey de Grey propone una serie de intervenciones terapéuticas para reparar el daño molecular y celular que se acumula con el tiempo. Estas intervenciones incluyen la eliminación de las células senescentes, que dejan de dividirse y secretan sustancias inflamatorias; la restauración de la longitud de los telómeros, que son las estructuras que protegen los extremos de los cromosomas; la prevención de la glicación, que es la reacción química que altera las proteínas; y la eliminación de las mutaciones en el ADN mitocondrial, que afectan a la producción de energía celular. Otra posible vía para alcanzar la inmortalidad biológica sería la manipulación genética. Algunos genes están relacionados con la longevidad, como el gen FOXO3, que regula el estrés oxidativo, la inflamación y el metabolismo. Al modificar estos genes, se podría aumentar la esperanza de vida y la salud de los individuos. De hecho, se ha demostrado que ciertas variantes genéticas están asociadas con una mayor probabilidad de vivir más de 100 años. La inmortalidad biológica tendría algunas ventajas, como la posibilidad de disfrutar de una vida más larga y saludable, sin sufrir las enfermedades y el deterioro físico y mental que conlleva el envejecimiento. Además, se podría aprovechar la experiencia y el conocimiento de las personas mayores, que podrían seguir contribuyendo a la sociedad de forma activa. Sin embargo, también tendría algunos inconvenientes, como el riesgo de sobrepoblación, la escasez de recursos, el aumento de las desigualdades, la pérdida de la diversidad genética y el aburrimiento existencial. Además, la inmortalidad biológica no garantizaría la protección frente a otras causas de muerte, como los accidentes, la violencia o las catástrofes naturales. La inmortalidad digital Otra forma de vivir para siempre sería lograr la inmortalidad digital, es decir, trasladar la conciencia humana a un soporte informático. Esto implicaría crear una copia digital del cerebro, con todos sus recuerdos, personalidad y emociones, y alojarla en un servidor, una nube o un robot. De esta manera, se podría preservar la identidad y la continuidad de la persona más allá de la muerte física. Algunos científicos y empresas están trabajando en esta dirección, utilizando técnicas como la neuroimagen, la inteligencia artificial y la realidad virtual. Por ejemplo, el proyecto BrainEx pretende crear un mapa detallado de la estructura y la actividad del cerebro humano, utilizando escáneres de alta resolución y algoritmos de aprendizaje automático. El objetivo es poder reconstruir el cerebro en un formato digital y simular su funcionamiento. Otro ejemplo es el proyecto Nectome, que ofrece la posibilidad de preservar el cerebro mediante un proceso de vitrificación, que consiste en inyectar un líquido que evita la formación de cristales de hielo y mantiene intactas las conexiones neuronales. El propósito es poder escanear el cerebro en el futuro y extraer la información que contiene. La inmortalidad digital tendría algunas ventajas, como la posibilidad de escapar de las limitaciones del cuerpo físico, explorar nuevos entornos virtuales, interactuar con otras mentes digitales y acceder a una gran cantidad de información y conocimiento. Además, se podría elegir el aspecto, la edad y las características de la representación digital, así como modificarla según las preferencias o las necesidades. Sin embargo, también tendría algunos inconvenientes, como la pérdida de la conexión con el mundo real, la dependencia de la tecnología, la vulnerabilidad a los ataques informáticos, la falta de privacidad y la incertidumbre sobre la autenticidad y la singularidad de la conciencia digital. Además, la inmortalidad digital plantearía cuestiones éticas, legales y sociales, como el derecho a la vida, la propiedad intelectual, la responsabilidad moral y la dignidad humana. Conclusión En conclusión, vivir para siempre es un sueño que ha inspirado a muchas generaciones, pero que también plantea muchos desafíos y dilemas. La ciencia y la tecnología están avanzando hacia la posibilidad de alcanzar la inmortalidad, ya sea biológica o digital, pero aún quedan muchos obstáculos y riesgos que superar. Además, la inmortalidad no es solo una cuestión técnica, sino también filosófica y existencial. ¿Qué sentido tendría la vida si no tuviera fin? ¿Qué valor tendría el tiempo si fuera infinito? ¿Qué implicaría la inmortalidad para la identidad, la libertad y la felicidad humanas? Estas son algunas de las preguntas que deberíamos hacernos antes de aspirar a vivir para siempre. Puedes leer más y comentar en mi web, en el enlace directo: https://luisbermejo.com/este-podcast-te-cambiara-la-vida-zz-podcast-05x17/ Puedes encontrarme y comentar o enviar tu mensaje o preguntar en: WhatsApp: +34 613031122 Paypal: https://paypal.me/Bermejo Bizum: +34613031122 Web: https://luisbermejo.com Facebook: https://www.facebook.com/ZZPodcast/ X (twitters): https://x.com/LuisBermejo y https://x.com/zz_podcast Instagrams: https://www.instagram.com/luisbermejo/ y https://www.instagram.com/zz_podcast/ Canal Telegram: https://t.me/ZZ_Podcast Canal WhatsApp: https://whatsapp.com/channel/0029Va89ttE6buMPHIIure1H Grupo Signal: https://signal.group/#CjQKIHTVyCK430A0dRu_O55cdjRQzmE1qIk36tCdsHHXgYveEhCuPeJhP3PoAqEpKurq_mAc Grupo Whatsapp: https://chat.whatsapp.com/FQadHkgRn00BzSbZzhNviThttps://chat.whatsapp.com/BNHYlv0p0XX7K4YOrOLei0
367 BCE – 205 BCE “What goes up must come down” Isaac Newton The death of Sri Lanka's visionary king, Devanampiya Tissa, ushered in a period of unnerving calm. All seemed fine with the state – and yet something, somewhere, was going fatally wrong, leaving it wide open to invasion.If there was a serious shortcoming in the reign of Devanampiya Tissa, it was his apparent lack of children; and in the 30 years that followed two of his brothers and possibly even an uncle took up the royal reins, with little obvious beneficial effect – as far as the country was concerned. First up was Uththiya, one of old king Mutasiva's many sons. His ten year rule from 267 BCE to 257 BCE is a marvel of obscurity. He was succeeded by his brother, Mahasiwa, whose own ten year rule, from 257 BCE – 247 BCE, goes almost as unremembered - apart from the fact that he built the Nagarangana Monastery. By the time Mahasiwa's uncle, Surathissa, took the throne in 247 BCE, things were clearly going most seriously wrong, and the young country would have been wise to take to heart the words of the Egyptian writer, Suzy Kassem: “Never follow a follower who is following someone who has fallen. Its why the whole world is falling apart.” For by now the kingdom itself was falling apart. It had become so ineptly run and poorly defended as to lay itself wide open to invasion – the first recoded invasion of the country from South India. Three kings, and three decades on from the kingdom's apparent apogee, the governance of the country had clearly eroded – and badly. The systems, protections, administration, and defences put in by the last two or three great kings had broken down, the reason a matter on which speculation could rest until the return of the dodo itself. Why did it all go so very wrong? No one knows. But the state no long had its eye on the ball. Clearly Devanampiya Tissa's heirs had in very short supply the ten perfections that make the life of Buddha aspirants positive: morality, renunciation, wisdom, energy, forbearance, truthfulness, resolution, kindness, equanimity, and liberality. The invasion came in the ignominious form of couple of Tamil horse traders, Sena and Guttik.Spotting the ultimate commercial opportunity (a kingdom) in the weak rule of King Surathissa, the traders met little resistance in conquering Anuradhapura and slaughtering the ineffectual Surathissa. They were to rule it for 22 years, the first of a succession of Tamil invaders. It was a humiliating end to the golden years of the Vijayan dynasty. And yet, like the immortal jellyfish, Turritopsis dohrnii, dead, in this case, did not mean dead - for the fight had not quite left the Vijayans.Out there in the wilderness lay Asela, another son of old King Mutasiva. After Surathissa was killed, Asela took refuge far south in the Kingdom of Ruhuna – a sub kingdom that had been established by Mahanaga, another son of King Mutasiva.Descending on the horse trader kings with much shattered dignity to put right, Asela killed them in battle. After decades of poor rule followed by a pair of asset stripping Indian merchants, there was much that King Asela had to put right. But the task proved too much for him and his own rule was brought to an abrupt end 10 years later in 205 BCE when he himself was killed in battle by Ellara, an invading Tamil Chola.That he should meet such an end, after so much trouble to restore his family's right to reign, seems almost unfair – but as Nicholas Sparks gloomily observed ““life, I've learned, is never fair. If people teach anything in school, that should be it.” Ellara was to rule the Anuradhapuran Kingdom for 44 years, smashing the awesome edifice of Vijayan rule that had already given the island so much of its lasting cultural identity. The illustration is from a painting by Rajni Perera, one of Sri Lanka's leading contemporary artists; based in Canada.The recording is read by David Swarbrick; and all disappointing, inexact and incomplete renderings of Sinhala and Tamil names are entirely of this own unintentional and apologetic making, for which your forgiveness is asked.The Ceylon Press currently produces three podcast shows.1. The Jungle Diaries (www.theceylonpress.com/thejunglediariespodcast)2. The History of Sri Lanka (www.theceylonpress.com/thehistoryofsrilankapodcast)3. Poetry from the Jungle (www.theceylonpress.com/poetryfromthejunglepodcast)
Seg 1: There's a fascinating type of jellyfish called Turritopsis dohrnii, also known as the immortal jellyfish that can reverse its aging process and essentially become young again. Could this jellyfish unlock immortality in humans? Guest: Maria Pia Miglietta, Associate Professor of Marine Biology at Texas A&M University and Principal Investigator at the Miglietta Lab Seg 2: View From Victoria: The Premier has had words with BC Ferries brass, and has told them its current issues are unacceptable and changes needed. The Vancouver Sun's Vaughn Palmer is here with his take on the day's headlines. Seg 3: Despite Canada's inflation rate falling to its lowest point in two years at 2.8%, food prices remain persistently high, experiencing a significant increase of 8.3% compared to the previous year. Guest: Mike von Massow, Associate Professor of Food Economics at the University of Guelph Seg 4: Netflix's Deep Fake Love is a reality dating show that incorporates deepfake technology. Guest: Jeff Hancock, Harry and Norman Chandler Professor of Communication at Stanford University and Founding Director of the Stanford Social Media Lab Seg 5: A new report is diving into the idea of allowing cell phones in schools as a way to emphasize and enhance classroom learning. Guest: Dr. Lana Parker, Associate Professor of Education at Windsor University Seg 6: Monday Morning Quarterbacks 27-0 shutout win over Edmonton which is the second time the Lions have shut out the Elks this season. Guest: Rick Campbell, Head Coach of the BC Lions Seg 7: The B.C. port strike continues as workers have rejected a mediated contract offer, potentially leading to further job action at some of Canada's busiest ports. Guest: Mark Thompson, Professor Emeritus of Organizational Behaviour and Human Resources at UBC's Sauder School of Business Learn more about your ad choices. Visit megaphone.fm/adchoices
There's a fascinating type of jellyfish called Turritopsis dohrnii, also known as the immortal jellyfish that can reverse its aging process and essentially become young again. Could this jellyfish unlock immortality in humans? Guest: Maria Pia Miglietta, Associate Professor of Marine Biology at Texas A&M University and Principal Investigator at the Miglietta Lab Learn more about your ad choices. Visit megaphone.fm/adchoices
Auszug aus dem 13. Kapitel. Die mysteriöse Forscherin Fabienne arbeitet für eine Gruppe, die sich "Turido" nennt. Reporterin Selma und ihr Partner Marcel finden heraus, welcher Name hinter diesem Begriff steckt: Turritopsis dohrnii - die unsterbliche Qualle. Was hat das zu bedeuten? Wird es Fabienne Selma erzählen? Und was ist mit Marcel los? "Lebenslust - Die Reporterin im Appenzellerland" ist im orte Verlag erschienen. https://www.philipp-probst.ch/wp-content/uploads/2022/05/Vorschau_2022_02_Probst_Lebenslust.pdf
PB&J, minus the PB, and completely different______________________Is immorality possible? Are jellyfish really fish or is “sea jelly” more accurate? Is one of the only truly immortal animals smaller than your pinkie fingernail? Did you know that sea jellies are brainless, heartless, and bloodless? What does a four point five millimeter long invertebrate eat? Today with your host, Devon, and co-hosts, Chet and Cap, you will learn everything there is to know about the Immortal Jellyfish, Turritopsis dohrnii.The riddle for the next episode is “Dear Valentine: Orchids are pink, insects like me are too, say your prayers, I might just eat you. Who am I?” You can send in your answers, questions, and episode suggestions to animals@kingdomanimaliapod.com and our website is at https://kingdomanimaliapod.com/kazpk.Further Reading (Discovery of Immortality):Can a Jellyfish Unlock the Secret of Immortality?Links:Comic | Memory Quiz | Read Transcript | Check Works CitedUntil next time, keep exploring this amazing Kingdom: Animalia.Kingdom: Animalia - A Zoology Podcast for Kids is an animal podcast from Kingdom: Animalia Podcasts. You can support us on Patreon.
The turritopsis dohrnii is a type of immortal jellyfish. Interestingly, when it senses threat, it can regress and produce polyps that turn into young versions of the jellyfish. Learn more about this fascinating sea friend as hosted by Victor Varnado, KSN and Rachel Teichman, LMSW. Produced by Victor Varnado & Rachel Teichman Full Wikipedia here: https://en.wikipedia.org/wiki/Turritopsis_dohrnii WE APPRECIATE YOUR SUPPORT ON PATREON!https://www.patreon.com/wikilistenpodcast Find us on social media! https://www.facebook.com/WikiListen Instagram @WikiListen Twitter @Wiki_Listen Youtube Get bonus content on Patreon Learn more about your ad choices. Visit megaphone.fm/adchoices
A Sea Creature That Lives Forever. That story and more on H2O Radio's weekly news report about water. Headlines: Will the green prince be a green king? Every tenth of a degree counts, so there is still time to avoid climate tipping points. Immortality is fiction, of course—unless you're Turritopsis dohrnii. California is turning to a creature once hunted nearly to extinction and maligned as a nuisance as a climate hero.
Die Sendung mit der Ziege - Staffel 3, Folge 104, Episode 24Der Traum von der ewigen Jugend ist für die Quallenart Turritopsis dohrnii Realität. Die nur wenige Millimeter große Qualle kann sich immer wieder selbst verjüngen und so dem Tod ein Schnippchen schlagen. Ob der Jungbrunnen der "Unsterblichen Qualle" auch eines Tages uns Menschen zur Verfügung stehen wird, erfahrt Ihr in dieser Folge. Link zum Videocast: https://youtu.be/M8g4h2LH8NsArtikel:https://thebiologist.rsb.org.uk/biologist-features/everlasting-life-the-immortal-jellyfishhttps://academic.oup.com/g3journal/article/9/12/4127/6028122Bild-Nachweis:1. Bachware, Turritopsis dohrnii, CC BY-SA 4.02. Schema nach Ferdinando Boero, nachgezeichnet M. Ziege3. Roman Klementschitz, Wien, Nacktmull, CC BY-SA 3.04. Specialjake, Didelphis virginiana with young, CC BY-SA 3.0Alle Pod- und Videocastfolgen auf einen Blick: www.DieSendungMitDerZiege.deDir gefällt meine Sendung und Du möchtest meine Arbeit unterstützen? Dann wirf doch ein paar Münzen in den Hut!Support the show
Учёные всё ещё не могут однозначно ответить, зачем киты выбрасываются на берег, что за странные звуки раздаются на дне океана и как медузе из рода Turritopsis удаётся жить вечно. Об этих и других неразгаданных тайнах подводного мира рассказываем в свежем выпуске «Подкаста Лайфхакера».Прочитать этот и другие материалы вы можете на нашем сайте: https://lifehacker.ru/tajny-okeana/ А пройти опрос, чтобы мы могли узнать о вас лучше, вы можете тут: https://clck.ru/Zaor4 Вступайте в канал подкастов Лайфхакера в Telegram, в нём мы рассказываем много интересного о мире подкастов и обсуждаем новые эпизоды: https://t.me/podhacker Наша почта: podcasts@lifehacker.ru Другие соцсети нашего издания: VK: https://vk.com/lifehacker_ru Telegram: https://t.me/lifehackerru Twitter: https://twitter.com/ru_lh YouTube: https://www.youtube.com/user/lifehackertv
Ever wonder about the artificial intelligence helping us find and fight Parkinson's disease? What about the new methods for collecting energy from solar panels at night or how the tiny immortal jellyfish may help us massively extend our lifespans. Tune in to learn more!Robots that help.Artificial Intelligence and Robotics Uncover Hidden Signatures of Parkinson's Disease by New York Stem Cell Foundationhttps://neurosciencenews.com/parkinsons-ai-robotics-20259/Integrating Deep Learning and Unbiased Automated High-Content Screening to Identify Complex Disease Signatures in Human Fibroblasts by Lauren Schiff, et al.https://www.nature.com/articles/s41467-022-28423-4#Sec10What is Parkinsons by Ahmad Elkouzihttps://www.parkinson.org/understanding-parkinsons/what-is-parkinsonsOur Agenda by The Michael J. Fox Foundationhttps://www.michaeljfox.org/our-agendaSolar but at night.Stanford Engineers Invent a Solar Panel That Generates Electricity at Night by Grant Currinhttps://interestingengineering.com/stanford-solar-panel-nightNighttime Electric Power Generation at a Density of 50 mW/m2 Via Radiative Cooling of a Photovoltaic Cell by Sid Assawaworrarit, et al.https://aip.scitation.org/doi/10.1063/5.0085205How Do Solar Panels Work by Michael Dhar and Ailsa Harveyhttps://www.livescience.com/41995-how-do-solar-panels-work.htmlSolar Panels That Can Generate Electricity at Night Have Been Developed at Stanford by Rina Torchinskyhttps://www.npr.org/2022/04/07/1091320428/solar-panels-that-can-generate-electricity-at-night-have-been-developed-at-stanfJellyfish: the secret to life.The Secrets of the Immortal Jellyfish, Earth's Longest-Living Animal by Thomas Linghttps://www.sciencefocus.com/nature/immortal-jellyfish/Turritopsis dohrnii: The Life Cycle of the Immortal Jellyfish by The Real Immortal Jellyfishhttps://therealimmortaljellyfish.com/Cellular Reprogramming and Immortality: Expression Profiling Reveals Putative Genes Involved in Turritopsis dohrnii's Life Cycle Reversal by Yui Matsumoto and Maria Pia Migliettahttps://doi.org/10.1093/gbe/evab136Follow Curiosity Daily on your favorite podcast app to get smarter with Calli and Nate — for free! Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers.Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/ai-vs-parkinsons-dark-sun-power-death-proof-jellyfish
Just like any good superhero comic, we start this episode with the science going incredibly wrong. Think: vats of toxic waste producing evil mutants that ravage the city. Or maybe not so evil. It really depends on your perspective. Just like the X-men, genetic mutations get a bad rap in the public eye. But they aren't all nasty.Dr. Kaylee Byers speaks with data scientist and evolutionary biologist Dr. Brian Arnold on how the genetic ‘mistakes' known as variants occasionally encode incredible abilities. Odd elephants, immortality hiding in our ocean depths, and Rogue-ish bacteria are just a few examples. Dr. Arnold defends these genetic anomalies, and explains how they can make a huge difference to the future of humanity and life on this planet. Also joining us is marine biologist Dr. Maria Pia Miglietta, who shares an incredible ability sitting in our ocean depths. Immortality.So strap on your capes, because we're heading straight into the strange terrain of “heroic mutations.” Listen to Nice Genes! wherever you get your podcasts, brought to you by Genome British Columbia.Check out this episode's Learn-A-Long at the following link: https://bit.ly/3bey4XT Resources: Genetic Mutation - Nature Genomic mutation rates: What high-throughput methods can tell us Shane Campbell Staton Group - Tuskless Elephants Ivory poaching and the rapid evolution of tusklessness in African elephants - Science Real-Life X-Men: How CRISPR Could Give You Superpowers in the Future - synthego.com Indonesian divers have evolved bigger spleens to hunt underwater - Science Mutations may reveal how Tibetans can live on world's highest plateau - Science The Immortal Jellyfish - American Museum of Natural History Cellular reprogramming and immortality: Expression profiling reveals putative genes involved in Turritopsis dohrnii's life cycle reversal Transcriptome Characterization of Reverse Development in Turritopsis dohrnii (Hydrozoa, Cnidaria) Horizontal gene transfer and adaptive evolution in bacteria - nature reviews microbiology Horizontal gene transfer overrides mutation in Escherichia coli colonizing the mammalian gut - PNAS The Ship of Theseus Dilemma - Open Okstate See omnystudio.com/listener for privacy information.
The immortal jellyfish (scientific name – Turritopsis nutricula) was discovered in 1883 in the Mediterranean Sea. However, it's extremely unique regeneration powers were not known to researchers and scientists until the mid-1980s. In other words, this Jellyfish lives forever. The unique regeneration process of the immortal jellyfish is quite unique. Email: realnewsocala@gmail.com --- Support this podcast: https://anchor.fm/lee-leffingwell/support
Dans le classement des animaux vivant le plus longtemps, les 5 premières places sont trustée par des animaux aquatiques: 1- La méduse (Turritopsis nutricula) approche l'immortalité car, non seulement elle renouvelle ses cellules, mais elle peut retourner à un état larvaire en cas de stress. 2- L'éponge (Anoxycalyx joubini) est en réalité non pas un animal mais une colonie de cellules vivant ensemble, pourrait vivre plus de 10000 ans. Chaque individu ne vit tout au plus que 10 ans mais la colonie se renouvelle en permanence. 3 - La praire d'Islande (Arctica islandica) peut vivre plus de 500 ans. Un spécimen célèbre a été baptisé Ming, du nom de la dynastie au pouvoir en Chine lorsqu'il est né. 4 - Le requin du Groenland (Somniosus microcephalus) est l'un des plus gros requins carnivores de la planète. Il détient le record de longévité chez les vertébrés: 500 ans. 5- La baleine boréale (Balaena mysticetus) peut vivre jusqu'à 200 ans. C'est le record de longévité des mammifères. _______
Hey Blurtsters!The rain has eased up on the eastern coastline. But that hasn't stopped the Rona taking hold again and making life troublesome. We have cruise ships with Covid cases...hello Coral Princess! We have hospitals at crisis point, not that it was ever quiet. Does that mean it's time to "Shut the border?!" Tonight we talk all things Covid because it's been a while since it's been in the news.We also blurt about animals in our segment we call Nature Calls.And lastly we talk about people who have gone good stuff to make a positive change to our lives.Let's get on with the show Wencee and Kegsta.More: thenewblurt.substack.comThe Beatles Get Back documentary - Directed by Peter JacksonCovidMore than 100 people on a cruise ship that docked in NSW on Tuesday have tested positive to COVID-19Official COVID-19 vaccination daily rollout updateJonathan Pie - Put a F**king Mask On!Nature CallsAustralian “Firehawk” Raptors Intentionally Spread WildfiresAye-aye, Dumbo octopus, Turritopsis nutricula →Top 10 strangest animals in the worldGreat People That Did StuffAbraham Lincoln →Abe LincolnJames Web Space Telescope →NASA’s Webb Delivers Deepest Infrared Image of Universe YetJames Webb Telescope captures thousands of galaxies in first photo | USA TODAY (short version)President Biden and Vice President Harris Receive a Briefing on James Webb Space Telescope Images (long version)Follow us on our socials:YouTube - https://www.youtube.com/channel/UCI6sah68y5GKhtD-uE4W-FAFacebook - https://www.facebook.com/blurtstar/Instagram - https://www.instagram.com/blurtstar/Twitter - @BlurtNew This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit thenewblurt.substack.com
Welcome back! Todays ep:Catch ups so long it's basically the whole podSober Bonnie and Averill butchering the pronunciation of several wordsA lil jellyfish ✨background✨ and life cycle Immortal jellyfish?Do jellies sleepGreen fluorescent protein!!Sources for the nerds:Life cyclesRebecca Helm Lab Blog -https://jellybiologist.comImmortalityL. Martell, S. Piraino, C. Gravili & F. Boero (2016) Life cycle, morphology and medusa ontogenesis of Turritopsis dohrnii (Cnidaria: Hydrozoa), Italian Journal of Zoology, 83:3, 390-399SleepNath, R. D., Bedbrook, C. N., Abrams, M. J., Basinger, T., Bois, J. S., Prober, D. A., Sternberg, P. W., Gradinaru, V., & Goentoro, L. (2017). The jellyfish cassiopea exhibits a sleep-like state. Current Biology, 27(19), 2984-2990GFPChalfie, M. (1995), GREEN FLUORESCENT PROTEIN. Photochemistry and Photobiology, 62: 651-656.As always, we welcome any and all thoughts:Instagram: @soundsscientificTwitter: @soundscientific*views are our own and not the opinions of our employers or institutionWe are a tiny podcast so do your act of kindness for the day and click those like/subscribe/follow/share buttons *views are our own and not the opinions of our employers or institution*
Alec Baldwin sits down to tell his side of the horrific “Rust” shooting (00:21:40), an Indian Doctor prescribes eating cow poop to pregnant women, Pat's health is deteriorating, man with world's largest nose says it has its perks and MD man steals ED medicine from pharmacy (00:00:00) Timestamps Cup of Coffee in the Big Time (00:04:45) - Fun Fact: There is a species of jellyfish the Turritopsis dohrnii that is immortal (00:06:00) - Holidays: National Fritters Day, National Mutt Day, International Day For The Abolition Of Slavery (00:08:20) - This Day in History: James K. Polk Delivers “Manifest Destiny” Speech & The UN Removes Cannabis From List Of Most Dangerous Drugs (00:11:45) - December 2nd Births - Britney Spears, Aaron Rogers (00:14:40) - Honorable Mentions - Pat's Health & Nose, School Shooting In Michigan, Supreme Court Abortion Hearing (00:21:40) - #2 - Alec Baldwin Special Coming Out Where Alec Baldwin Did Not Pull The Trigger (Clip) (00:26:30) - #1 - The Cream Of The Crop Today Is You, The Hive!! We Appreciate Everyone Sharing That We Were Your #1 Most Listened To Podcast Over The Year. TikTok International Moment (00:33:00) - Africa - Safari tour gets destroyed by giant Elephant in Musth (00:36:55) - India- Doctor is prescribing pregnant women eat cow shit to keep them healthy and have safe birth (00:39:55) - Belarus - Alexander Lukashenko is pretty much taking over Ukraine now (00:42:15) - Turkey - Man with world's biggest nose claims that nose can also help him smell better (00:48:10) - A Maryland Man was arrested after fleeing a pharmacy with his ED Medicine and hiding in his mom's basement These stories, and much more, brought to you by our incredible sponsors: Black Buffalo - Black Buffalo, the world's ONLY smokeless tobacco alternative that delivers the same experience as traditional long cut and pouches, just without any tobacco leaf or stem. Go to www.blackbuffalo.com and use Code HARDFACTOR for 25% off your first order Adam & Eve - Just enter offer code HARDFACTOR at checkout....and you'll get 50% off almost any item. Go check out www.adamandeve.com today, select one item and get 50% off including FREE shipping when you enter offer code HARDFACTOR Fight Camp- Go To www.GetRoman.com/HardFactor and if you're prescribed, get $15 off your first month of ED treatment. Predicit: Get up to $40 matched when you deposit at Predictit.org/promo/hardfactor40 and make money betting on politics! Go to store.hardfactor.com and patreon.com/hardfactor to support the pod with incredible merch and bonus podcasts Other Places to Listen: Spotify, Google Podcasts, Stitcher, Lots More... Watch Full Episodes on YouTube
Dans le classement des animaux vivant le plus longtemps, les 5 premières places sont trustée par des animaux aquatiques: 1- La méduse (Turritopsis nutricula) approche l'immortalité car, non seulement elle renouvelle ses cellules, mais elle peut retourner à un état larvaire en cas de stress. 2- L'éponge (Anoxycalyx joubini) est en réalité non pas un animal mais une colonie de cellules vivant ensemble, pourrait vivre plus de 10000 ans. Chaque individu ne vit tout au plus que 10 ans mais la colonie se renouvelle en permanence. 3 - La praire d'Islande (Arctica islandica) peut vivre plus de 500 ans. Un spécimen célèbre a été baptisé Ming, du nom de la dynastie au pouvoir en Chine lorsqu'il est né. 4 - Le requin du Groenland (Somniosus microcephalus) est l'un des plus gros requins carnivores de la planète. Il détient le record de longévité chez les vertébrés: 500 ans. 5- La baleine boréale (Balaena mysticetus) peut vivre jusqu'à 200 ans. C'est le record de longévité des mammifères.
Dans le classement des animaux vivant le plus longtemps, les 5 premières places sont trustée par des animaux aquatiques: 1- La méduse (Turritopsis nutricula) approche l'immortalité car, non seulement elle renouvelle ses cellules, mais elle peut retourner à un état larvaire en cas de stress. 2- L'éponge (Anoxycalyx joubini) est en réalité non pas un animal mais une colonie de cellules vivant ensemble, pourrait vivre plus de 10000 ans. Chaque individu ne vit tout au plus que 10 ans mais la colonie se renouvelle en permanence. 3 - La praire d'Islande (Arctica islandica) peut vivre plus de 500 ans. Un spécimen célèbre a été baptisé Ming, du nom de la dynastie au pouvoir en Chine lorsqu'il est né. 4 - Le requin du Groenland (Somniosus microcephalus) est l'un des plus gros requins carnivores de la planète. Il détient le record de longévité chez les vertébrés: 500 ans. 5- La baleine boréale (Balaena mysticetus) peut vivre jusqu'à 200 ans. C'est le record de longévité des mammifères. _______
La puntata 379 del nostro podcast vede alla conduzione Giuliano e Giorgio. Giuliano, su suggerimento di un ascoltatore, ci racconta la storia della medusa immortale (Turritopsis dohrnii), un organismo davvero particolare che potrebbe insegnarci molto anche se difficilmente ci renderà immortali. L'intervento esterno di questa settimana è curato da Giuliana che intervista Giovanni Francesco Ciani, ricercatore in fisica dell'Università di Bari, che ci parlerà degli ultimi risultati dell'esperimento LUNA (Laboratory for Underground Nuclear Astrophysics). Tornati in studio Giorgio sfoggia la sua abilità nel non saper raccontare le barzellette, ma dopo ci racconta di un recente lavoro in cui alcuni ricercatori hanno studiato la possibilità di cuocere del pollo con laser di varia lunghezza d'onda. Che sia l'inizio di un nuovo tipo di cucina?
⚠️ Découvrez du contenu EXCLUSIF (pas sur la chaîne) ⚠️ ⇒ https://the-flares.com/y/bonus/ ⬇️⬇️⬇️ Infos complémentaires : sources, références, liens... 0:01:52 Presentation de Francois-Xavier Pellay 0:03:31 Quels sont les processus du vieillissement chez l'humain ? 0:07:10 Pourquoi le vieillissement existe chez les organismes et qu'est ce qui fixe la limite d'environ 120 ans de durée de vie maximale chez l'humain ? 0:15:19 La durée de vie maximale est-elle programmée génétiquement ? 0:26:00 Sur quel type de recherche Francois-Xavier Pellay se focalise t-il ? 0:34:16 Quel est le domaine qui semble être le plus prometteur pour améliorer drastiquement la longévité en bonne santé à l'aide des technosciences ? 0:38:41 Quelle est la promesse des sénolytics ? 0:43:56 L'approche de David Sinclair et des NAD+ ? 0:49:49 Doit-on faire reconnaitre le vieillissement comme une maladie pour inciter la recherche ? 0:55:43 Quelles sont les sociétés / domaines les plus prometteurs pour la longévité en bonne santé ? 1:06:41 Comment expliquez que le financement de la recherche sur le vieillissement soit une toute petite fraction du financement sur la recherche contre le cancer ou Alzheimer ? 1:12:09 Y-a t-il un changement de perception autour de la recherche sur le vieillissement ? 1:15:09 L'évolution de la discipline de la biogérontologie sur les prochaines décennies ? 1:27:56 Est ce que nous pourrons atteindre un jour un stade d'amortalité similaire à certains organismes comme la méduse Turritopsis nutricula, le homard, certains coraux ou certains arbres ? 1:32:08 Quelles sont les objections que vous rencontrez le plus souvent et comment y répondez-vous ? Le contenu vous intéresse ? Abonnez-vous et cliquez sur la
Imagina si tuvieras visión de rayos x, o la habilidad de ver mundos invisibles, o ¡¿qué tal ser inmortal...?! Todos deseamos un día levantarnos y tener superpoderes, pero… ¿los animales? ¡Nacieron con ellos! El día de hoy aventúrate con nosotros a explorar Las habilidades Más Sorprendentes del Mundo Animal. ¡Animales ven colores que nosotros no! ¿Inmortal como una medusa? (Turritopsis nutricula)Escarabajos con superfuerza (Scarabaeus satyrus) El animal más feroz del mundo (Mellivora capensis) Un oso CASI indestructible (Tardigrado) ¡La arena de la playa está hecha de EXCREMENTO de peces! (Scarus coeruleus) Los hipopótamos usan protector solar (Hippopotamus Amphibius) ¡Hormigas que explotan! (Colobopsis saundersi) Ave con cejas del largo de un bebé (Pteridophora alberti) ¡Pájaro que grita como mono! Y mucho más… (Menura novaehollandiae) Zarigüeyas, serpientes y… ¡¿Dinosaurios?! (Didelphis marsupialis) Delfines, equipo anti-explosivos (Delphinus delphis) - Animals Making Kids Lives Better (2) #1CA --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/universos-abiertos/message Support this podcast: https://anchor.fm/universos-abiertos/support
Saviez vous que l'immortalité existait sur Terre ? Si vous n'êtes pas encore abonné, n'hésitez pas à le faire dès à présent !
Science & Faith 01: Handling the Conflict of Science & Faith The first in a mini-series on science and the Bible, we go deeper in to the idea that God wrote 2 books: the Word and the World. And what does Aristotle and a fixed-earth cosmology have to do with it all? Intro & Preamble: 0:32 * Episode 12 - “Don't Give Moses Horns” (https://www.followingthefire.com/12) * Followingthefirepodcast@gmail.com * www.followingthefire.com * Steve's Twitter@HeySteveMartin (https://twitter.com/HeySteveMartin) Cool Science Thing: 4:24 * God of the gaps (https://en.wikipedia.org/wiki/God_of_the_gaps) * Immortal Jellyfish (https://en.wikipedia.org/wiki/Turritopsis_dohrnii) Does it move?: 7:09 * BioLogos.org (https://biologos.org) * Young Earth creationism (https://en.wikipedia.org/wiki/Young_Earth_creationism) * Aristotle (https://en.wikipedia.org/wiki/Aristotle) * The fixed-earth concept (Geocentric Model (https://en.wikipedia.org/wiki/Geocentric_model)) * Fixed-earth scriptures: * 1 Chronicles 16:30 (https://www.biblegateway.com/passage/?search=1%20Chronicles%2016%3A30&version=NIV) * Psalm 93:1 (https://www.biblegateway.com/passage/?search=Psalm+93%3A1&version=NIV) * Psalm 105:5 (https://www.biblegateway.com/passage/?search=psalm+105%3A5&version=NIV) * 1 Samuel 2:8 (https://www.biblegateway.com/passage/?search=1+Samuel+2%3A8&version=NIV) * Moving-sun scriptures: * Psalm 19:4-6 (https://www.biblegateway.com/passage/?search=Psalm+19%3A4-6&version=NIV) * Ecclesiastes 1:5 (https://www.biblegateway.com/passage/?search=Ecclesiastes+1%3A5&version=NIV) * Nicolaus Copernicus (https://en.wikipedia.org/wiki/Nicolaus_Copernicus) * Copernican Heliocentrism (https://en.wikipedia.org/wiki/Copernican_heliocentrism) * Martin Luther (https://en.wikipedia.org/wiki/Martin_Luther) * Galileo Galilei (https://en.wikipedia.org/wiki/Galileo_Galilei) * Heliocentrism (https://en.wikipedia.org/wiki/Heliocentrism) * Dialogue Concerning the Two Chief World Systems (https://en.wikipedia.org/wiki/Dialogue_Concerning_the_Two_Chief_World_Systems) Interpretation Problems: 14:30 * 2 books written by God: The Word and the World * Scientific Method (https://en.wikipedia.org/wiki/Scientific_method) * Biblical Scholarship (https://en.wikipedia.org/wiki/Biblical_studies) * “You knit me together in my mother's womb.” - Psalm 139:13-14 (https://www.biblegateway.com/passage/?search=Psalm%20139%3A13-14&version=NIV) * Romans 1:20 (https://www.biblegateway.com/passage/?search=Romans%201%3A20&version=NIV) * St. Augustine of Hippo (https://en.wikipedia.org/wiki/Augustine_of_Hippo) * Book: “The Literal Meaning of Genesis” by St. Augustine (https://amzn.to/2UktqP7) Join our Patreon (http://patreon.com/followingthefire) - we'd love your support and we have some fantastic patron perks!
Debra, Diana, and Jesi talk about The Paul O'Sullivan Band, a mystery signal from space, and The Lucky 15... and a real immortal animal. Tell us what sparks your interest on twitter (@interest_spark), facebook (@sparkmyinterestpodcast), and instagram (@sparkmyinterestpodcast)! Email a crazy story or interesting article to sparkmyinterestpodcast@gmail.com and we might just discuss it on the show! Articles and other sources: https://en.wikipedia.org/wiki/Turritopsis_dohrnii https://www.cbsnews.com/news/four-strangers-all-named-paul-osullivan-form-a-band-despite-living-in-different-cities-around-the-world/ https://www.livescience.com/proxima-centauri-mystery-radio-beam.html https://mysteriousuniverse.org/2019/05/the-strange-miracle-of-nebraskas-lucky-15/ --- Support this podcast: https://anchor.fm/sparkmyinterest/support
Biocognitive Science Institute: Exploring the Causes of Health in Cultural Contexts
The Turritopsis is a jellyfish that never dies. Although it has no brain and no heart, when it reaches a certain limit of aging, it simply drops to the bottom of the ocean and triggers polyps that generate stem cells to reproduce itself for another generation. So, unless killed by a predator, the Turritopsis is immortal. Based on what I have discovered from the regenerating process, I am going to discuss ways to approximate what the Turritopsis does using our consciousness. This does not mean that I am promising immortality. Instead, I am proposing techniques that add to the gene expression of longevity. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/biocognitiveculture/message Support this podcast: https://anchor.fm/biocognitiveculture/support
Jasmin erzählt eine Geschichte aus ihrem neuen Sachbuch "Abschied von Hermine", das bald angekündigt wird. Es geht um Eintagsfliegen, die nur 5 Minuten erwachsen sind und um Quallen, die niemals sterben müssen. Lorenz erzählt eine Geschichte über die Dünndarm-Zeitschaltuhr, zu deren Erforschung er selbst beigetragen hat (wenn auch nicht im Selbstversuch). Was im Mäuse-Dünndarm passiert, wenn zu unterschiedlichen Zeiten mal fettreiche Kost verabreicht wird, mal Antibiotika, mal Kot, oder die Mäuse währenddessen unter Jetlag leiden, erfahrt ihr in dieser Geschichte. Außerdem erzählt Lorenz, warum er eine Wespe heiraten würde. (Foto: Richard Bartz) Material • Paper zu Dolania americana: https://onlinelibrary.wiley.com/doi/abs/10.1002/iroh.1977.3510620306 • Wikipedia-Artikel über die "unsterbliche Qualle": https://de.wikipedia.org/wiki/Turritopsis_dohrnii • Die von Lorenz besprochene Arbeit gibt es hier jedoch leider nur hinter der Bezahlschranke: https://www.cell.com/cell/fulltext/S0092-8674(20)31069-2
En el episodio de hoy hablamos de los cnidarios en general, de los hidrozoos en particular, unos animales que doblan de forma habitual muchas reglas que consideramos constantes entre los animales. Nos dan también unas cuantas pistas que nos ayudarán cuando hablemos sobre el sexo y la muerte más adelante. Unos ejemplos de cnidarios:https://commons.wikimedia.org/wiki/Category:Cnidaria#/media/File:Cnidaria.pngUna ilustración del ciclo de vida: https://commons.wikimedia.org/wiki/File:Reproductive_cycle_of_jellyfish.jpgUn esquema del tallo de un sifonóforo. A la derecha hay dibujos de cada uno de los clones individuales especializados en distintas funciones: https://www.researchgate.net/profile/Agustin_Schiariti/publication/265509301/figure/fig3/AS:366073498095617@1464290131167/Figura-4-Esquema-de-una-colonia-tipica-de-sifonoforo-con-sus-diferentes-divisiones-y.pngUna foto de una carabela portuguesa: https://upload.wikimedia.org/wikipedia/commons/c/c3/Portuguese_Man-O-War_%28Physalia_physalis%29.jpgUn vídeo de un gigantesco sifonóforo del género Apolemia, ¡más de 40 metros!: https://twitter.com/SchmidtOcean/status/1247231196347674625 Un vídeo de un sifonóforo en movimiento: https://youtu.be/8KZsrDGLUJQUna foto de Hydra viridissima, nótese el pequeño clon que le está creciendo en un lado: https://commons.wikimedia.org/wiki/File:Hydra_viridissima2.jpg#/media/File:Hydra_viridissima2.jpg Una foto de una de las medusitas fénix de Turritopsis dohrnii: https://upload.wikimedia.org/wikipedia/commons/7/74/Turritopsis_dohrnii.jpg
First, a moment of silence for George Floyd and all the other Black lives lost to police brutality, racial injustice, and white supremacy. We need to stay angry, make change, and vote for people who will hold these murderers accountable. It is important that we do not forget.Better Than Human stands in solidarity with the Black community and the protesters who are challenging systemic racism and inequality. If you are as outraged by racism as we are, but not sure how to help, these are some good places to donate to: ACLU: https://action.aclu.org/give/nowGeorge Floyd Memorial Fund: https://www.gofundme.com/f/georgefloydJustice For Breonna Taylor: https://justiceforbreonna.org/Run With Maud: https://www.runwithmaud.com/Campaign Zero: https://www.joincampaignzero.org/#vis...The Bail Project: https://bailproject.org/Bail Funds For Protesters By City/State: https://www.communityjusticeexchange#BlackLivesMatterThen onto Turritopsis dohrnii, the Immortal Jellyfish. Is it really immortal? Depends on your definition of immortal. Jennifer and Amber argue their definitions, and just like the ketchup on eggs argument, cannot agree. Most jellyfish species have a fixed life-span, which varies by species from hours to months. Turritopsis dohrnii is the only jellyfish known to have developed the ability to return to its infant from, and then start it's life over again indefinitely through transdifferentiation. Listen and learn about this interesting species, and it's implications for science. Note: Jellyfish ARE animals (says Jennifer), and the movie talked about near the end of the episode is "In Time."Visit our website betterthanhumanpodcast.comFollow us on Twitter @betterthanhuma1on Facebook @betterthanhumanpodcaston Instagram @betterthanhumanpodcastEmail us at betterthanhumanpodcast@gmail.comWe look forward to hearing from you, and we look forward to you joining our cult of weirdness!#betterthanhuman #cultofweirdness
Éste es el episodio 139 de 3 Cosas Que Ayer No Sabía, el del jueves 26 de marzo de 2020. 01. Turritopsis dohrnii Hoy tengo que comenzar casi con una fe de erratas porque Christian Rodríguez no sólo me envió lainformación que di ayer en el podcast sino también un audio que se me olvidó incluir. Cuando se lo comenté por privado aprovechó para contarme algo muy curioso sobre un tipo de medusa la Turritopsis Dohrnii que es prácticamente inmortal ya que sus células se regeneran continuamente. De hecho, sólo “fallece” por enfermedades o devorada por algún depredador, pero no por degeneración (de viejo) como nos pasa al resto de especies animales: https://es.m.wikipedia.org/wiki/Turritopsis_dohrnii 02. Crímenes Ilustrados El escritor y diseñador Modesto garcía ha lanzado en Twitter Crímenes Ilustrados, un juego en el que te conviertes en investigador para resolver un misterio. Con el hashtag #CrímenesIlustrados1, lo que me hace pensar que habrá más de una entrega, Modesto comparte la ilustración de la escena de un crimen y pregunta ¿Se suicidó o fue asesinado? Además de las pistas que pueda haber en la propia imagen, en ella están etiquetas otras cuentas de usuarios que también aportarán sus propias pistas: https://twitter.com/modesto_garcia/status/1242872971179540480 Aunque lo vi esta mañana lo lanzó el día 25 de marzo y anuncia que dará la resolución en 6 días, así que aún estás a tiempo de participar en el juego. Por cierto, esta primera ilustración la firma Javi De Castro, a quien descubrió al principio de empezar yo este podcast con su serie de cómics interactivos The Eyes: https://www.javidecastro.com/theeyes 03. Etimología de Yucatán Y termino con el dato que me pasa otro oyente, en esta ocasión Daniel Gómez Gibal que me escribe por Telegram desde México para contarme la etimología de Yucatán, que es uno de los estados de su país. Me cuenta Daniel que “cuando los españoles llegaron, y le preguntaban a los mayas el nombre de esas tierras, ellos le contestaban "u uy ku t'aan", que el lengua maya significa “oye como hablan”. * Resultado del sorteo del pack AddPeel del jueves 26 de marzo: Jesús Relinque Recuerda que puedes comprar tus vinilos adhesivos para personalizar el cargador de tu móvil aquí: https://amzn.to/32GBQRa *Mañana viernes 27 de marzo además será el último capítulo de la 2ª temporada. Despedida: Suscríbete a este podcast en cualquier plataforma y no te olvides de dejarme alguna review o comentario, ¡que siempre ayuda! A mí me encuentras en Twitter y Telegram por @almajefi. Escríbeme y cuéntame qué te parece este podcast y, por qué no, enséñame cosas nuevas. Con dió.
For folks in the USA, happy Martin Luther King Jr. Day! This week on Petri Dish Nathan and Sean discuss the biology of aging. What does it actually mean to age, when some animals out there are biologically immortal and get to just hang out forever until they get eaten? What happens on a cellular level when we age? What can we learn from other species about the aging process? This is the first part of a two-part series -- next week we'll discuss human aging in the context of what we can try to do to slow or halt it!References:https://www.pnas.org/content/early/2020/01/07/1916548117https://www.sciencedirect.com/science/article/pii/S0092867413006454https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247388/https://www.sciencedirect.com/science/article/pii/S2211124714010195https://www.pnas.org/content/early/2019/09/12/1904611116https://en.wikipedia.org/wiki/Nothobranchius_furzerihttps://onlinelibrary.wiley.com/doi/full/10.1111/j.1474-9726.2012.00847.xhttps://link.springer.com/article/10.1007/s11357-013-9597-9https://www.nature.com/articles/ncomms14063https://royalsocietypublishing.org/doi/full/10.1098/rsbl.2010.0539https://onlinelibrary.wiley.com/doi/full/10.1002/bies.201000132https://www.sciencedirect.com/science/article/pii/S1568163714000622https://en.wikipedia.org/wiki/Turritopsis_dohrniihttps://oaktrust.library.tamu.edu/handle/1969.1/173118https://www.sciencedirect.com/science/article/pii/S1055790316303359https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964061/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326690/https://www.sciencedirect.com/science/article/pii/S0047637417300015https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0547-yhttps://www.pnas.org/content/115/8/1801.shorthttps://www.hindawi.com/journals/omcl/2019/4502819/abs/https://www.sciencedirect.com/science/article/pii/B978012411596500006Xhttps://www.sciencedirect.com/science/article/pii/S0092867416309813
“And today we’re talking about a tiny little long-lived sea booger. But more on that later. The long lived stuff. Not the booger stuff.” Description Like many sea creatures, the jellyfish is found all over the world’s oceans. They prefer temperate to tropical regions. They are believed to have originated in the pacific but may … Continue reading Episode 102 – Turritopsis Jellyfish: To Be Young Again
撰文/闵嘉德(Josh Mitteldorf) 翻译/汪婕舒逆转衰老1905年,荷兰生物学家弗里德里克·斯多皮布林克(Friederich Stoppenbrink)研究了真涡虫(Planaria)的生命周期。这是一种扁虫,通常出现在淡水池塘里。他注意到,当这种动物食物不足时,会有计划地吃掉自己。从最可消耗的器官(性器官)开始,慢慢吃到消化系统(在饥荒年代反正用处也不大),接着是肌肉。在这个过程中,真涡虫变得越来越小,直到只剩下最宝贵的部分——大脑和神经细胞。斯多皮布林克称,当他再次喂食时,它们又重新生长,迅速长回了之前吃掉的部分。此外,它们的外表和行为看起来都像年轻的真涡虫一样。当那些没有经历过饥荒的同龄真涡虫因衰老而逐渐死亡时,这些经历了饥饿和重生的真涡虫依然活蹦乱跳。这个实验可以重复一遍又一遍,只要斯多皮布林克一直让它们经历挨饿和重生的过程,它们就会一直活下去,丝毫没有衰老的迹象。能够返老还童的灯塔水母 图/Shane Anderson/2010年,灯塔水母(Turritopsis nutricula)一夜成名,只因它在科学新闻中被捧上了“永生”的宝座。灯塔水母的生命周期分为水螅体与水母体,幼体以水螅体的形式固着生活,成年后以水母体的形式游泳生活。但一旦遇到环境恶化,成年的灯塔水母能倒退为水螅形态,从头再活一次。这是通过将分化细胞变回干细胞来完成的,与正常的发育方向(干细胞到分化细胞)截然相反。从本质上说,就是在生命的单行线上逆向行驶。腐尸甲虫(Trogoderma glabrum)也有一个类似的绝招,但只有挨饿的时候才用。它们的一生都在树林中的尸体上度过,成长中会连续经历6个不同的幼虫阶段—先像蛆、接着像马陆、然后像水黾,最后才变成六足的甲虫。1972年,美国威斯康辛大学的两名昆虫学家在试管中将处于第6阶段的幼虫(即将变成成虫之前)分离了出来。他们发现,如果食物短缺,它们能够退回幼虫的第5阶段;如果几天都吃不到食物,它们会逐渐缩小和倒退,直到变成刚孵出来的蛆虫的样子;如果恢复喂食,它们又能再次向前生长,经历正常的发育阶段,变成成虫,并拥有正常的寿命。他们一次又一次地重复这个周期,让它们先长到幼虫的第6阶段,然后让它们挨饿,退回第一阶段。这样,这些甲虫的寿命从8周延长到了两年多。持续再生与性水螅是一种放射对称的无脊椎动物,在身体上方有一个口,周围包围着触手。如果触手被切掉,还能够长回来——就像希腊神话中的勒拿九头蛇一样,因而共享着相同的英文名(Hydra)。它们用触手抓住水蚤等浮游生物,并以此为食。也有些水螅是绿色的,依赖着在它们透明肌肤下的共生藻类。曾经有人对水螅开展了4年的研究,从野外捕捉了各种年龄的样本,发现它们似乎不会自然死亡,随着年龄增长被捕食者吃掉或生病的几率也不会增加。在人体内,有些细胞(比如血细胞、皮肤细胞和胃黏膜细胞)会不断死亡和重生。而水螅似乎全身都是这样,每隔几天便能从干细胞基底中自我更新。一些细胞会掉落和死亡;但还有一些,假如体积足够大,就能像萌芽一样从原来那只水螅的身体上伸出来,长成一只克隆的水螅。这是一种古老的繁殖方式,完全不需要性就可以完成。对水螅来说,有性繁殖似乎并不是必须的,而只是偶尔的放纵。近期一篇文章声称,水螅其实是会衰老的,其表现是它克隆的速度会变慢。研究者认为,克隆体会继承“父母”的年龄。他的假说是,只有有性繁殖才能“重置”衰老的时钟。如果这是真的,那么,水螅衰老的方式就回到了单细胞的原生生物,比如草履虫。草履虫的衰老我们在此前的专栏中已经介绍过。对它们而言,克隆的次数记录在端粒中。当端粒短到一定程度时,细胞便衰老而无法分裂。只有有性繁殖可以重置端粒上的“时钟”。这一古老的衰老方式迫使个体必须与群体分享自己的基因。高等生物(包括你和我)也有端粒,并且,端粒在我们的一生中通常会越来越短,直到我们死去(癌细胞则逃离了端粒的束缚)。只有在繁殖时,两个不同亲代的配子细胞形成新的个体时,端粒才会重置。衰老的开关蜂后和工蜂拥有相同的基因,它们的寿命却相去甚远。对蜂后来说,是蜂王浆(更确切地说是蜂后浆)关掉了衰老的开关。当一个新的蜂群形成时,育幼工蜂会选择—就目前所知是随机选择— 一只幼虫,喂以蜂王浆。蜂王浆中某些具备生理活性的成分促使这只幸运的幼虫成长为一只蜂后,而不是一只工蜂。蜂王浆赋予了蜂后过度发育的生殖腺,使其长出了独具一格的体型。蜂后在职业生涯的开端会飞出去一次,在这过程中,她会与十几只不同的雄峰进行交配,并将精子存储起来,以备今后数年使用。工蜂围绕的蜂后 图/topbest.ph工蜂只能活几个星期,然后会因衰老而死亡。虽然蜂后的基因与工蜂完全相同,却没有一点衰老的迹象。蜂后可以生存和产卵许多年,如果蜂群足够健康且稳定,甚至可以延续几十年。她们是不老的奇迹,只有在用尽婚飞时存储的精子之后才会死去。直到那一刻,她还是能够产卵的,可是这些卵未能受精,只能长成无刺的雄峰。接着,过去尽心侍奉蜂后的工蜂就会杀死这个衰败的皇后:团团围住并将它刺死。这意味着什么?衰老的方式和持续时间五花八门。许多人认为,衰老是物理定律造成的,任何东西用久了都会磨损,只不过有些东西比其他东西更耐久一些。其实,衰老与磨损的相似性只是一个幻觉,衰老与熵增定律并无关系。我们看到,大自然让生命体拥有了五花八门的衰老形式。与生命体的所有特征一样,衰老也来自于进化。它塑造了寿命的长短,使其能够适应它们所处的生态系统。本文发表于《科学世界》2017年12月发布于 2019-04-17
撰文/闵嘉德(Josh Mitteldorf) 翻译/汪婕舒逆转衰老1905年,荷兰生物学家弗里德里克·斯多皮布林克(Friederich Stoppenbrink)研究了真涡虫(Planaria)的生命周期。这是一种扁虫,通常出现在淡水池塘里。他注意到,当这种动物食物不足时,会有计划地吃掉自己。从最可消耗的器官(性器官)开始,慢慢吃到消化系统(在饥荒年代反正用处也不大),接着是肌肉。在这个过程中,真涡虫变得越来越小,直到只剩下最宝贵的部分——大脑和神经细胞。斯多皮布林克称,当他再次喂食时,它们又重新生长,迅速长回了之前吃掉的部分。此外,它们的外表和行为看起来都像年轻的真涡虫一样。当那些没有经历过饥荒的同龄真涡虫因衰老而逐渐死亡时,这些经历了饥饿和重生的真涡虫依然活蹦乱跳。这个实验可以重复一遍又一遍,只要斯多皮布林克一直让它们经历挨饿和重生的过程,它们就会一直活下去,丝毫没有衰老的迹象。能够返老还童的灯塔水母 图/Shane Anderson/2010年,灯塔水母(Turritopsis nutricula)一夜成名,只因它在科学新闻中被捧上了“永生”的宝座。灯塔水母的生命周期分为水螅体与水母体,幼体以水螅体的形式固着生活,成年后以水母体的形式游泳生活。但一旦遇到环境恶化,成年的灯塔水母能倒退为水螅形态,从头再活一次。这是通过将分化细胞变回干细胞来完成的,与正常的发育方向(干细胞到分化细胞)截然相反。从本质上说,就是在生命的单行线上逆向行驶。腐尸甲虫(Trogoderma glabrum)也有一个类似的绝招,但只有挨饿的时候才用。它们的一生都在树林中的尸体上度过,成长中会连续经历6个不同的幼虫阶段—先像蛆、接着像马陆、然后像水黾,最后才变成六足的甲虫。1972年,美国威斯康辛大学的两名昆虫学家在试管中将处于第6阶段的幼虫(即将变成成虫之前)分离了出来。他们发现,如果食物短缺,它们能够退回幼虫的第5阶段;如果几天都吃不到食物,它们会逐渐缩小和倒退,直到变成刚孵出来的蛆虫的样子;如果恢复喂食,它们又能再次向前生长,经历正常的发育阶段,变成成虫,并拥有正常的寿命。他们一次又一次地重复这个周期,让它们先长到幼虫的第6阶段,然后让它们挨饿,退回第一阶段。这样,这些甲虫的寿命从8周延长到了两年多。持续再生与性水螅是一种放射对称的无脊椎动物,在身体上方有一个口,周围包围着触手。如果触手被切掉,还能够长回来——就像希腊神话中的勒拿九头蛇一样,因而共享着相同的英文名(Hydra)。它们用触手抓住水蚤等浮游生物,并以此为食。也有些水螅是绿色的,依赖着在它们透明肌肤下的共生藻类。曾经有人对水螅开展了4年的研究,从野外捕捉了各种年龄的样本,发现它们似乎不会自然死亡,随着年龄增长被捕食者吃掉或生病的几率也不会增加。在人体内,有些细胞(比如血细胞、皮肤细胞和胃黏膜细胞)会不断死亡和重生。而水螅似乎全身都是这样,每隔几天便能从干细胞基底中自我更新。一些细胞会掉落和死亡;但还有一些,假如体积足够大,就能像萌芽一样从原来那只水螅的身体上伸出来,长成一只克隆的水螅。这是一种古老的繁殖方式,完全不需要性就可以完成。对水螅来说,有性繁殖似乎并不是必须的,而只是偶尔的放纵。近期一篇文章声称,水螅其实是会衰老的,其表现是它克隆的速度会变慢。研究者认为,克隆体会继承“父母”的年龄。他的假说是,只有有性繁殖才能“重置”衰老的时钟。如果这是真的,那么,水螅衰老的方式就回到了单细胞的原生生物,比如草履虫。草履虫的衰老我们在此前的专栏中已经介绍过。对它们而言,克隆的次数记录在端粒中。当端粒短到一定程度时,细胞便衰老而无法分裂。只有有性繁殖可以重置端粒上的“时钟”。这一古老的衰老方式迫使个体必须与群体分享自己的基因。高等生物(包括你和我)也有端粒,并且,端粒在我们的一生中通常会越来越短,直到我们死去(癌细胞则逃离了端粒的束缚)。只有在繁殖时,两个不同亲代的配子细胞形成新的个体时,端粒才会重置。衰老的开关蜂后和工蜂拥有相同的基因,它们的寿命却相去甚远。对蜂后来说,是蜂王浆(更确切地说是蜂后浆)关掉了衰老的开关。当一个新的蜂群形成时,育幼工蜂会选择—就目前所知是随机选择— 一只幼虫,喂以蜂王浆。蜂王浆中某些具备生理活性的成分促使这只幸运的幼虫成长为一只蜂后,而不是一只工蜂。蜂王浆赋予了蜂后过度发育的生殖腺,使其长出了独具一格的体型。蜂后在职业生涯的开端会飞出去一次,在这过程中,她会与十几只不同的雄峰进行交配,并将精子存储起来,以备今后数年使用。工蜂围绕的蜂后 图/topbest.ph工蜂只能活几个星期,然后会因衰老而死亡。虽然蜂后的基因与工蜂完全相同,却没有一点衰老的迹象。蜂后可以生存和产卵许多年,如果蜂群足够健康且稳定,甚至可以延续几十年。她们是不老的奇迹,只有在用尽婚飞时存储的精子之后才会死去。直到那一刻,她还是能够产卵的,可是这些卵未能受精,只能长成无刺的雄峰。接着,过去尽心侍奉蜂后的工蜂就会杀死这个衰败的皇后:团团围住并将它刺死。这意味着什么?衰老的方式和持续时间五花八门。许多人认为,衰老是物理定律造成的,任何东西用久了都会磨损,只不过有些东西比其他东西更耐久一些。其实,衰老与磨损的相似性只是一个幻觉,衰老与熵增定律并无关系。我们看到,大自然让生命体拥有了五花八门的衰老形式。与生命体的所有特征一样,衰老也来自于进化。它塑造了寿命的长短,使其能够适应它们所处的生态系统。本文发表于《科学世界》2017年12月发布于 2019-04-17
撰文/闵嘉德(Josh Mitteldorf) 翻译/汪婕舒逆转衰老1905年,荷兰生物学家弗里德里克·斯多皮布林克(Friederich Stoppenbrink)研究了真涡虫(Planaria)的生命周期。这是一种扁虫,通常出现在淡水池塘里。他注意到,当这种动物食物不足时,会有计划地吃掉自己。从最可消耗的器官(性器官)开始,慢慢吃到消化系统(在饥荒年代反正用处也不大),接着是肌肉。在这个过程中,真涡虫变得越来越小,直到只剩下最宝贵的部分——大脑和神经细胞。斯多皮布林克称,当他再次喂食时,它们又重新生长,迅速长回了之前吃掉的部分。此外,它们的外表和行为看起来都像年轻的真涡虫一样。当那些没有经历过饥荒的同龄真涡虫因衰老而逐渐死亡时,这些经历了饥饿和重生的真涡虫依然活蹦乱跳。这个实验可以重复一遍又一遍,只要斯多皮布林克一直让它们经历挨饿和重生的过程,它们就会一直活下去,丝毫没有衰老的迹象。能够返老还童的灯塔水母 图/Shane Anderson/2010年,灯塔水母(Turritopsis nutricula)一夜成名,只因它在科学新闻中被捧上了“永生”的宝座。灯塔水母的生命周期分为水螅体与水母体,幼体以水螅体的形式固着生活,成年后以水母体的形式游泳生活。但一旦遇到环境恶化,成年的灯塔水母能倒退为水螅形态,从头再活一次。这是通过将分化细胞变回干细胞来完成的,与正常的发育方向(干细胞到分化细胞)截然相反。从本质上说,就是在生命的单行线上逆向行驶。腐尸甲虫(Trogoderma glabrum)也有一个类似的绝招,但只有挨饿的时候才用。它们的一生都在树林中的尸体上度过,成长中会连续经历6个不同的幼虫阶段—先像蛆、接着像马陆、然后像水黾,最后才变成六足的甲虫。1972年,美国威斯康辛大学的两名昆虫学家在试管中将处于第6阶段的幼虫(即将变成成虫之前)分离了出来。他们发现,如果食物短缺,它们能够退回幼虫的第5阶段;如果几天都吃不到食物,它们会逐渐缩小和倒退,直到变成刚孵出来的蛆虫的样子;如果恢复喂食,它们又能再次向前生长,经历正常的发育阶段,变成成虫,并拥有正常的寿命。他们一次又一次地重复这个周期,让它们先长到幼虫的第6阶段,然后让它们挨饿,退回第一阶段。这样,这些甲虫的寿命从8周延长到了两年多。持续再生与性水螅是一种放射对称的无脊椎动物,在身体上方有一个口,周围包围着触手。如果触手被切掉,还能够长回来——就像希腊神话中的勒拿九头蛇一样,因而共享着相同的英文名(Hydra)。它们用触手抓住水蚤等浮游生物,并以此为食。也有些水螅是绿色的,依赖着在它们透明肌肤下的共生藻类。曾经有人对水螅开展了4年的研究,从野外捕捉了各种年龄的样本,发现它们似乎不会自然死亡,随着年龄增长被捕食者吃掉或生病的几率也不会增加。在人体内,有些细胞(比如血细胞、皮肤细胞和胃黏膜细胞)会不断死亡和重生。而水螅似乎全身都是这样,每隔几天便能从干细胞基底中自我更新。一些细胞会掉落和死亡;但还有一些,假如体积足够大,就能像萌芽一样从原来那只水螅的身体上伸出来,长成一只克隆的水螅。这是一种古老的繁殖方式,完全不需要性就可以完成。对水螅来说,有性繁殖似乎并不是必须的,而只是偶尔的放纵。近期一篇文章声称,水螅其实是会衰老的,其表现是它克隆的速度会变慢。研究者认为,克隆体会继承“父母”的年龄。他的假说是,只有有性繁殖才能“重置”衰老的时钟。如果这是真的,那么,水螅衰老的方式就回到了单细胞的原生生物,比如草履虫。草履虫的衰老我们在此前的专栏中已经介绍过。对它们而言,克隆的次数记录在端粒中。当端粒短到一定程度时,细胞便衰老而无法分裂。只有有性繁殖可以重置端粒上的“时钟”。这一古老的衰老方式迫使个体必须与群体分享自己的基因。高等生物(包括你和我)也有端粒,并且,端粒在我们的一生中通常会越来越短,直到我们死去(癌细胞则逃离了端粒的束缚)。只有在繁殖时,两个不同亲代的配子细胞形成新的个体时,端粒才会重置。衰老的开关蜂后和工蜂拥有相同的基因,它们的寿命却相去甚远。对蜂后来说,是蜂王浆(更确切地说是蜂后浆)关掉了衰老的开关。当一个新的蜂群形成时,育幼工蜂会选择—就目前所知是随机选择— 一只幼虫,喂以蜂王浆。蜂王浆中某些具备生理活性的成分促使这只幸运的幼虫成长为一只蜂后,而不是一只工蜂。蜂王浆赋予了蜂后过度发育的生殖腺,使其长出了独具一格的体型。蜂后在职业生涯的开端会飞出去一次,在这过程中,她会与十几只不同的雄峰进行交配,并将精子存储起来,以备今后数年使用。工蜂围绕的蜂后 图/topbest.ph工蜂只能活几个星期,然后会因衰老而死亡。虽然蜂后的基因与工蜂完全相同,却没有一点衰老的迹象。蜂后可以生存和产卵许多年,如果蜂群足够健康且稳定,甚至可以延续几十年。她们是不老的奇迹,只有在用尽婚飞时存储的精子之后才会死去。直到那一刻,她还是能够产卵的,可是这些卵未能受精,只能长成无刺的雄峰。接着,过去尽心侍奉蜂后的工蜂就会杀死这个衰败的皇后:团团围住并将它刺死。这意味着什么?衰老的方式和持续时间五花八门。许多人认为,衰老是物理定律造成的,任何东西用久了都会磨损,只不过有些东西比其他东西更耐久一些。其实,衰老与磨损的相似性只是一个幻觉,衰老与熵增定律并无关系。我们看到,大自然让生命体拥有了五花八门的衰老形式。与生命体的所有特征一样,衰老也来自于进化。它塑造了寿命的长短,使其能够适应它们所处的生态系统。本文发表于《科学世界》2017年12月发布于 2019-04-17
We've unlocked our 11-episode Patreon series – Dr. Lisa-ann Gershwin, and occasionally the two of us, dive deep into jellyfish species and phyla. Find stories and science on: - Aurelia labiata (the moon jelly) - Turritopsis dohrnii (the immortal jelly) - Chrysaora achlyos (the black sea nettle) - Bazinga rieki (the little trickster who eats sunlight) - Chironex fleckeri (the deadly box jelly) - Aequoria victoria (the nobel-prize worthy crystal jelly) - Ctenophores (the comb jellies) - The Irukandjis (the doom jellies) - Siphonophores (colonies of stringy, stingy thingies) - Polyorchis penincilatus (the disappearing jelly) - & Salpidae (your long lost pelagic cousins) Find musical credits and show notes at futureecologies.net/listen/unlocked-jellyfish-overlords (http://www.futureecologies.net/listen/unlocked-jellyfish-overlords) For early access to bonus episodes and other content, join us at patreon.com/futureecologies (http://www.patreon.com/futureecologies) Support this podcast
When it comes to living a long life, demographers, epidemiologists, gerontologists and other researchers on aging have long puzzled over the theoretical question of the maximum potential for human lifespan, along with the host of proposed practices we can implement that help us achieve that potential. There is, after all, in the past decade alone a veritable laundry list of tactics we can use to make ourselves more age resistant, from nutrients, vitamins and pills such as , aspirin, metformin, , , , , and to lifestyle practices such as shivering our asses off, self-imposed starvation, fecal transplants, strict veganism, injecting into ourselves growth hormone, testosterone, stem cells, exosomes, the blood of younger healthy humans and speaking of younger humans, simply “having more children”. Fact is, compared to the Biblical Methuselah, who purportedly lived to the ripe old age of 969, we don’t seem to be moving the anti-aging dial much. In fact, researchers estimate that in the U.S. today, and, disturbingly, now plummeting due to high rates of chronic diseases (many of which are preventable with simple lifestyle changes you’ll learn about in this podcast). Currently – despite , the longest-lived modern person in the world on actual record is , who died in 1997 at the exact age of 122 years and 164 days. Yet, when we observe nature, some amount of immortality, or at least a significant amount of enhanced life extension, appears to be achievable. Take the naked mole rate, for example. The naked mole rat’s cells themselves seem to make proteins – the molecular machines that make bodies work – more accurately than us humans, preventing it from developing age-related illnesses like Alzheimer’s. Unlike humans, the way these ugly little creatures handle glucose doesn’t seem to change with age either, reducing their susceptibility to diseases like diabetes. The naked mole rat isn’t the only animal scientists are now probing to pick the lock of long life. With a rampant metabolism and a heart rate of 1,000 beats a minute, the common hummingbird should, on paper, be riddled with rogue free radicals (the oxygen-based chemicals that make mammals old by gradually destroying DNA, proteins and fat molecules), but the tiny birds seem relatively bulletproofed against heart disease. Then there are lobsters, which seem to have evolved a protein which repairs the telomere tips of their DNA, allowing for a decreased rate of telomere shortening that most animals are incapable of. Finally, as if rats, hummingbirds and lobsters weren’t enough to make us longevity seeking humans a bit jealous, we mustn’t forget one animal on Earth that may hold the master key to immortality: the Turritopsis dohrnii, also known as the “Immortal Jellyfish”. Most jellyfish, when they reach the end of life, die and melt into the sea, but not the Turritopsis dohrnii. Instead, it sinks to the bottom of the ocean floor, where its body folds in on itself – assuming the jellyfish equivalent of the fetal position – and regenerates back into a baby jellyfish in a rare biological process called transdifferentiation, in which its old cells somehow transform into young cells. So is there a human equivalent of the type of immortality “powers” these animals seem to have tapped into? Many in popular anti-aging and longevity circles have suggested that – in the next several decades – we could indeed unlock the secrets to living to approximately 120 to 140 years old, and many biohackers and anti-aging enthusiasts such as , , , and and even lil ol’ me are striving to live greater than 160 years old. The purpose of this podcast is not to delve into the relatively advanced longevity secrets of these fringe biohackers, but instead to reveal everything you need to know about why the world’s more traditionally living longevity all-stars not only live longer but also tend to live better. They have strong connections with their family and friends. They’re active. They wake up in the morning knowing that they have a purpose, and the world, in turn, reacts to them in a way that propels them along. An overwhelming majority of them still enjoy life. They share these common behavioral and lifestyle characteristics, such as family coherence, avoidance of smoking, plant-based diet, moderate and daily physical activity, social engagement, and situations where people of all ages are socially active and integrated into the community, despite all of them being from different areas of the world and of different races, nationalities and religions. That’s not to say that biohacking for longevity and better living through science isn’t beneficial. After spending nearly two decades deeply immersed in the health, fitness, nutrition and longevity industry, I’ve come to a growing realization that an open embrace of both the modern science and the ancestral wisdom could indeed allow one to live a long and healthy lifespan that rivals and even exceeds that of our ancestors. Perhaps that’s why my children and I engage in wild plant foraging (a longevity tactic you’ll learn more about in this podcast), but do so using a that allows us to identify everything from mushrooms to plants with incredible accuracy, allowing us to tap into a bit of better living through science to not get poisoned or make fatal mistakes our ancestors might have while foraging; why I own a quaint and simple, off-grid, barn-style home in the forest where we grow most of our own food, yet fill that barn with tens of thousands of dollars of modern anti-aging biohacking equipment; and why the last time I disappeared into a seven day high-country elk bowhunt in the mountains of Colorado, I had a neatly tucked away into my camouflage backpack. But in this podcast, rather than learning about fancy devices you can spend tens of thousands of dollars or fringe biohacks that will get you plenty of weird looks from your neighbor, you will discover exactly how to use proven ancestral tactics to live a happy, long and fulfilled life. So you can think of today's podcast as a cookbook for longevity that gives you all the low-hanging fruit and teaches you all the basics of living a long and happy life. During this two-part episode, in part one you'll discover... The 12 Ways to Enhance Your Longevity -Don't smoke...10:19 When you stop smoking, your body responds immediately Noticeable improvements within 90 days Sexual performance Cardio vascular After 1 year, like nothing ever happened Adrenal glands need to adapt to the lack of nicotine Use an adaptogenic herb complex Take a taurine supplement once per day for two months Diet rich in pro proanthocyanidine Use a good air filter Don't just stop; implement a strategy to aid your repair and recovery FUM essential oil vaping pen (LINK NEEDED) -Eat wild plants...14:20 Xeno-hormetic effect Not a fan of "plant paradox" diets Book: Eating On the Wild Side (LINK) Higher vegetable, lower meat intake -Avoid processed and packaged foods...18:10 First two ingredients often found in processed "health foods" Artificial sweetener Vegetable oil Difficult to eat processed/packaged foods when you're eating right Aim for 80% real food, 20% p/p foods -Eat legumes...22:37 High in non-meat protein, amino acids, slow burning carbs Eat other carbs (sweet potatoes, carrots, quinoa etc.) alongside the legumes Article: -Low-level physical activity...25:56 Enjoyable exercise; rarely engage in high-intensity training Hack your environment Standing desk Kettle bells in the cubicle Pomodoro breaks Take the stairs! Walking treadmill while blogging, podcasting, etc. Visiting the gym should be optional, unless you're training for an event, pro athlete, etc. Sitting for 8 straight hours negates any efficacy from a gym session -Prioritize social engagement...29:00 Podcast: -Drink alcohol (in moderation)...32:15 Podcast: Reduces risk of cardiovascular disease and certain cancers Mediterranean diet Boosts benefits of low-level activity even more (these habits build off one another) I haven't been drunk in 6 years, but I have a drink every day (red wine, moscow mule, "Ben and Jitters") -Calorie restriction and fasting...37:38 Intermittent fasting (12-16 hours) Fasting mimicking diet (40% of normal calorie intake) My own practice: Intermittent fast 1-2x per month, 24 hour fast (dinner to dinner) 4x per year, fasting mimicking diet Podcast: Book by the same name (LINK) -Possess a strong life purpose...42:08 Be able to say your purpose in life in one succinct sentence Quick tips: What did you like to do when you were a kid? What puts you in the flow, or the zone? Book: The Subtle Art of Not Giving a F*CK (LINK) "Think about the things that make you forget to eat and poop." -Lower your stress levels...45:00 Chronic stress at the root of inflammation, age-related diseases Don't avoid stress; learn to manage it Ruthlessly eliminate haste and hurry from your life -Engage in a belief in a higher power...47:20 Believe there's a story for your life, that you fit into a bigger picture Study: -Remain reproductively useful...50:17 If you want to replenish the earth, nature will want to keep you around Article: Old, horny Italians (LINK) In part 2, recorded from Runga in the Dominican Republic, I respond to questions from the audience, including: -What are the 2019 health trends...56:00 CBD Keto Stem cell booths Fasting -What is your view about high animal protein and how IGF-1 impacts longevity...58:53 -What's the best way to handle crinkle/crunch when bending at the knees...1:01:50 -What are the top 3 bio hacks for human optimization?...1:03:24 All comes down to the mitochondria Mineral-infused water Sunlight (photobiomodulation) Grounding with the earth (PEMF) -Does high-fat coffee break your fast?...1:05:53 Anything with calories breaks your fast -Top 5 quick tips for raising kids...1:07:11 Don't say "no" unless their life is in danger. Educate, let them learn to make decisions for themselves Adequate Vitamin D and K Genetically test your kids Teach how to deal with the cold Footwear (lots of bare feet) -Top 3 tips for increasing longevity...1:12:52 -What are your thoughts on sunblock and sunglasses?...1:14:50 -The thought of eating a diet only of foods in season and allowing a break from naturally occurring plant toxins for longevity...1:17:38 -What are your top 3 tests in correlating lab/company frequency to monitor your health?... DNA (once in your life) Comprehensive blood panel once a year Dutch test -What type of diet would you recommend for a family of four with a budget of $100/week?...1:23:18 Calorie and nutrient dense foods Invest in half a cow, vertical gardening setup -How do you find the right balance between the physical/tangible elements of what you teach and the spiritual/intangibles?...1:25:44 Episode Sponsors: -. Contains 2 Bags Kion Coffee and 1 Bottle Kion Aminos Tablets. This is Kion’s Favorite Combo to Support Fasting! - Medical-Grade, Full-Body Light Therapy. "It's the only light therapy device I'd ever recommend. Give it a try: you won't be disappointed." Use code "ben" at checkout and receive a nice bonus gift with your order. - combines turmeric with smooth coconut milk, cinnamon, ginger, lemon balm and two super mushrooms to create a warm relaxation beverage. Use discount code "greenfield" at checkout and receive 20% off your entire purchase! Got a question for me about the 12 ways you can increase your longevity? Just leave a comment below and I'll reply!
Ook al hebben kinderen op dit moment vakantie, hun nieuwsgierigheid staat nooit uit. Als bewijs hiervoor nodigen we deze week elke dag een kind uit die een vraag aan een wetenschapper mag stellen. Want achter een antwoord op een kindervraag zit vaak meer dan je zou denken. Vandaag is het de beurt aan Juan Tristan (11), een jongetje uit Heukelum dat nu al weet dat hij heel graag wetenschapper wil worden. Hij had gelezen dat de kwallensoort Turritopsis dohrnii zichzelf vanuit een volwassen toestand terug jong kan maken en dat dit dier daardoor onsterfelijk is. Zouden wij dat ook kunnen met een beetje genen van deze kwal? We vragen het aan Han Brunner, humaan geneticus aan het Radboud UMC en de Universiteit Maastricht.
If you've ever felt there's more to your health, fitness, and human spirit than meets the eye, then do we have the What Doesn't Kill us show for you. Today I'll be talking with Scott Carney, investigative journalist, anthropologist, and author of a fantastic paradigm busting book and journey, What Doesn't Kill us. And that's just what I want to talk with him about today, about how freezing water, extreme altitude, and environmental conditioning can renew our lost evolutionary strength – oh goodie!!! That plus we'll talk about climbing mountains in shorts, dancing indoors in the rain, why you don't want to go floppy, brown fat over white, breathless pushups, a mutiny on a mountain, spartan races, eating tapeworms, a mental umbrella, and what in the world Turritopsis dohrnii, the so-called “immortal jellyfish” has to do with anything! What Doesn't Kill Us Self-Improvement and Self-Help Topics Include: What's an Immortal Jellyfish and what does it have to do with anything? Who is Wim Hof, aka the Iceman? Why did an investigative reporter want to visit Wim Hof? What happened after only seven days with the Iceman? What was going on with the body? What can we learn about our own bodies from immersion in the cold? What does the human body physiologically when put in cold water (or snow)? What does breathing have to do with anything? What's the importance of rapid breathing? What's the importance of breath-holding? What is Brown Fat? What's the master switch of life? Why is brown fat so important and do we still have it? What can we learn from Samoset, the first Native American to meet the pilgrims? Who is Rob Pickels at the former Boulder Center for Sports Science? What can we learn from Laird Hamilton and the Millennium Wave? How does the cold affect diabetes? How does the cold affect auto-immune disorders? How does the cold affect Parkinson's disease? Who is Brian MacKenzie and what is HIIT training? What does meditation have to do with any of this? Scott Carney on Why What Doesn't Kill Us Makes Us Stronger!!! Wim Hoff - Iceman | Health | Fitness | Running | Weight Lifting | Spiritual | Spirituality | Meditation | Mindfulness | Inspirational | Motivational | Self-Improvement | Self-Help | Inspire For More Info Visit: www.InspireNationShow.com
We’d like to thank Focus Features for sponsoring this video – and for inviting us to pre-screen their summer 2015 film “Self/Less”. It’s a sci-fi flick that explores memory, consciousness, and immortality, and it made us think about the types of immortality that already exist here on Earth. A big thanks to Focus Features for supporting MinuteEarth! http://www.focusfeatures.com/selfless Thanks also to our Patreon patrons: - Today I Found Out - Jeff Straathof - Maarten Bremer - Mark - BurmansHealthShop - Alberto Bortoni - Avi Yashchin - Valentin - Nicholas Buckendorf - Antoine Coeur YOU can also support us on Patreon: https://www.patreon.com/minuteearth ___________________________________________ Want to learn more about the topic in this week’s video? Here are some key words/phrases to get your googling started: – negligible senescence: not showing signs of age-related progression – biological immortality: having a mortality rate that does not increase with increasing age ________________________ MinuteEarth provides an energetic and entertaining view of trends in earth’s environment – in just a few minutes! Created by Henry Reich With the MinuteEarth team: Alex Reich, Peter Reich, Emily Elert, Ever Salazar, Kate Yoshida, and Henry Reich. Music by Nathaniel Schroeder: http://www.soundcloud.com/drschroeder ________________________ Subscribe on YouTube: http://www.youtube.com/user/minuteear... And follow us on Vessel: https://www.vessel.com/shows/68917745... And here we are on iTunes: https://goo.gl/sfwS6n Also, say hello on: Facebook: http://facebook.com/minuteearth Twitter: http://twitter.com/MinuteEarth ________________________ References: Aubert, G. & Lansdorp, P. M. (2008) Telomeres and aging. Physiological Review 88(2): 557–579. http://simonadellemonache.com/dispens... Bavestrello, G. Sommer, C., and Sará, M. 1992. Bi-directional conversion in Turritopsis nutricula. In Aspects of Hydrozoan Biology. (J. Bouillon et al., editors). Scientia Marina 56 (2-3): 137-140. http://www.icm.csic.es/scimar/pdf/56/... Buffenstein R. (2008) Negligible senescence in the longest living rodent, the naked mole rat: Insights from a successfully aging species. Journal of Comparative Physiology B 178: 439-445. http://link.springer.com/article/10.1... Finch, C.E. (1998) Variations in senescence and longevity include the possibility of negligible senescence. Journal of Gerontology: Biological Sciences 53A(4): B235–239. http://biomedgerontology.oxfordjourna... Piraino, S., Boero, F., Aeschbach, B., Schmid, V. (1996) Reversing the life cycle: medusae transforming into polyps and cell transdifferentiation in Turritopsis nutricula (Cnidaria, Hydrozoa). Biological Bulletin 190: 302-312. http://www.researchgate.net/profile/F... Tian, X., Azpurua, J., Hine, C., Vaidya, A., Myakishev-Rempel, M., Ablaeva, J., Mao, Z., Nevo, E., Gorbunova, V., & Seluanov, A. (2013) High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature 499: 346–349. http://www.nature.com/nature/journal/... Image Credits: Nake Mole Rat - Buffenstein/Barshop Institute/UTHSCSA https://www.flickr.com/photos/jedimen... Naked Mole Rat - Roman Klementschitz, Wien https://en.wikipedia.org/wiki/File:Na... Chipmunk - Gilles Gonthier https://www.flickr.com/photos/gillesg... Capybara - Karoly Lorentey https://www.flickr.com/photos/lorente...
In this episode: * Krista's Mexico Vacation * Immortal Jellyfish * 80's Technology / Music * Devastating News from the Sandwich World * Manti Te'o The Legal Aliens podcast is Written and Presented by Ben Kent, Richard Simons and Krista Ristinen, and is produced and edited by Ben Kent. Voiceover provided by . The Legal Aliens Theme Tune was written and performed by Neil Button Other music in this is program is provided by - . Want to join in the fun? We'd love to hear from you: Call our voicemail line on 951-ALIENS-1 (951-254-3671 or (001) 951-254-3671 from the UK), email us: , Follow us on twitter or join our .
The Show Notes Corbomite voiceIntro Doppeltravel.com Interesting Fauna - Sub-Antarctic Shrimp - Turritopsis nutricula Green Zone and Goats Ask George - Christians? from Josh Arekelian - Randi coming out? from Jeff Sykes - Groups of three? from Christopher Thompson - iPod touch? from Luke Attorneys General Show close ........................ Mentioned in the Show John and Erik from John Sterling Ruth Studio ........................ Geo's Music: stock up! The catalog at iTunes The catalog at CD Baby ........................ Sign up for the mailing list: Write to Geo! Score more data from the Geologic Universe! Get George's edition Non-Coloring Book at Lulu, both as download and print editions. Have a comment on the show, a Religious Moron tip, or a question for Ask George? Drop George a line and write to Geo's Mom, too! Ms. Information says, "Trebuchet... and I am catapulted into a big plushy cushion of wackiness!"