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Welcome to another captivating episode of Impact Quantum! In today's exploration, our hosts, Frank La Vigne and Candice Gilhooly, dive deep into the ever-evolving world of quantum computing. From NVIDIA's GTC commentary and Bill Gates' views on quantum timelines to JPMorgan Chase's breakthrough in truly random randomness, there's plenty to unpack. As they navigate the buzz of photonic qubits, hybrid architectures, and the rise of quantum tech hubs, Frank and Candice lend their wit and wisdom to help demystify the quantum realm. Whether you're quantum curious or a seasoned physicist, this episode promises a healthy splash of sarcasm, caffeine-driven insights, and a glimpse into the potential of the quantum future.So, grab your favorite elixir and join us as we embark on another quantum-powered journey with Impact Quantum. Stay curious, caffeinated, and don't be the one still stuck in classical computing!Timestamps00:00 "Quantum Unraveled: Trends & Gossip"04:55 Quantum Computing Debate Impacts Market08:52 Quantum Computing's Rapid Advancements11:21 Microsoft's Quantum Pushback16:34 Quantum Computing: A Future Market Opportunity17:14 Embrace Quantum Computing Knowledge Now22:49 Title: "Canada's Quantum Conference Surge"25:16 Cost-Cutting Controversy at Microsoft29:04 Predicting Tech Trends Through Experience32:14 IBM's Pre-Assembled Computer Success33:47 Quantum Computing's Long-Term Importance37:58 Columbia University Phone Experience42:41 Casino Cheat via Pseudo-Random Exploit44:11 Quantum Computing's Impact on Randomness48:45 Remote Work Challenges Pre-Pandemic51:36 "Waterloo: Canada's MIT Equivalent"55:52 "Quantum Future: Stay Curious"
Dominique de Werra is an emeritus professor of Operations Research at EPFL (Ecole Polytechnique Federale de Lausanne) in Switzerland. His research fields include Combinatorial Optimization, Graph Theory, Scheduling and Timetabling. After spending a few years as an assistant professor in Management Sciences at the University of Waterloo (Canada) he joined the Math Department of EPFL. He conducted a collection of Operational Research projects (applied as well as theoretical) with a number of industrial partners. He is an associate editor of Discrete Applied Mathematics, Discrete Mathematics, Annals of Operations Research and a member of a dozen of editorial boards of international journals. From 1990 to 2000 Dominique de Werra was the Vice-President of EPFL; he was in charge of the international relations and represented his institution in many academy networks in Europe (like the CLUSTER network of excellence which he chaired). He was also in charge of all education programs of EPFL. He was President of IFORS (the International Federation of Operational Research Societies) from 2010 to 2012. In 1987-1988 he was President of EURO, the European Association of Operational Research Societies. In 1985–1986 he was President of ASRO, the Swiss Operations Research Society. In 1995 he was the laureate of the EURO Gold Medal. He has obtained Honorary Degrees from the University of Paris, the Technical University of Poznan (Poland) and the University of Fribourg (Switzerland). In 2012 he was awarded the EURO Distinguished Service Medal. He published over 200 papers in international scientific journals. He also wrote and edited several books. He was member of many committees in various countries of Europe and America (evaluation of institutions, accreditation, strategic orientation, etc.).
In this episode, Dr Elle Wadsworth talks to Dr James Nicholls from the University of Stirling about an opinion paper he co-authored with Professor Geoffrey Hunt on whether pleasure should receive more attention in public health-oriented alcohol research. They discuss what alcohol researchers and public health professionals can learn about ‘intoxication and pleasure' from drug research, the different ways that the pleasure of drinking is made more socially acceptable, and what more research on pleasure could do for policy and practice. · Why public health research has historically not explored the pleasure of alcohol intoxication [01:04]· Why this is an important topic to raise with the public health research community now [02:58]· Clarifying what type of pleasure is most neglected [04:55]· Measuring intoxication as pleasure and recognising the limitations of our methodologies [06:50]· Three broad reasons why additional attention should be paid to intoxication as pleasure [08:46]· What learning more about the pleasure of intoxication means for policy and practice [12:06]· The anticipation of publishing an opinion piece for debate [14:28]About Elle Wadsworth: Elle is an academic fellow with the Society for the Study of Addiction. She is based at the University of Bath with the Addiction and Mental Health Group and her research interests include drug policy, cannabis legalisation, and public health. Elle is also a senior analyst at RAND Europe, working on projects focusing on national and international drug policies. She holds a PhD in public health and health systems from the University of Waterloo (Canada), an MSc in addiction studies from King's College London (UK), and a BSc in chemistry from the University of Bristol (UK).About James Nicholls: James is a Senior Lecturer in Public Health at the University of Stirling, specialising in alcohol and drug policy research. Recent projects include leading a needs assessment for a safer drug consumption facility in Edinburgh, and a statutory review of the alcohol licensing system in Northern Ireland. He has also published recently on moral philosophy and drug policy advocacy. James was previously Director of Research and Policy at Alcohol Change UK, and Chief Executive Officer of Transform Drug Policy Foundation. James has no conflicts of interest to declare.Original article: Taking pleasure seriously: Should alcohol research say more about fun? https://doi.org/10.1111/add.16747 The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal. The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information. Hosted on Acast. See acast.com/privacy for more information.
Dr. Daniel Scott is a Professor and Research Chair in the Department of Geography and Environmental Management at the University of Waterloo (Canada). He has worked extensively on sustainable tourism for 25 years, with a focus on the transition to a low carbon tourism economy and adaptation to the complex impacts of a changing climate. In 2021, he was ranked in the world top 300 climate change scientists by Reuters. In 2023, he was recognized as one of Canada's top scholars when he was inducted as a Fellow the Royal Society of Canada. He has advised a wide range of governments and tourism organizations around the world, including the United Nations World Tourism Organization, United Nations Environment Programme, World Bank, European Tourism Commission, World Travel and Tourism Council, International Olympic Committee, OECD, the Caribbean Tourism Organization. He has also been a contributor to the UN Intergovernmental Panel on Climate Change Third, Fourth, Fifth Assessments and their 1.5°C special report. His tourism research publications have been downloaded over a half million times and have been featured in many leading media outlets, including The Economist, New York Times, Guardian, Washington Post, Wall Street Journal, BBC, Time, Scientific American, Sports Illustrated, National Geographic and many other others. Article: Ski resorts' era of plentiful snow may be over due to climate crisis, study finds Learn more about your ad choices. Visit megaphone.fm/adchoices
Cosa si intende per crittografia quantum-safe? Perché è importante per tutti colori che lavorano con tecnolgie web e quali sono i requisiti ed i blocker per l'adozione di massa? Possiamo parlare di una "minaccia quantistica" e quali tecnologie sono in fase di standardizzazione e di normativa? In questo episodio ospito Michele Mosca, co-fondatore di evolutionQ e professore all'Università di Waterloo (Canada), per parlare di come funzionano le tecnologie post-quantum rispetto a protocolli attuali come TLS e per approfondire cosa possono fare le aziende oggi per portarsi avanti e adottare protocolli quantum-safe gradualmente per consentire una migrazione fluida e senza impatti negativi. Link: EvolutionQ. Link: [White paper] Transitioning to a Quantum-Secure Economy. Link: 2022 Quantum Threat Timeline Report. Link: Post-Quantum Cryptography at AWS.
This is Garrison Hardie with your CrossPolitic Daily Newsbrief for Wednesday, November 23, 2022. I’m back ladies and gentleman! Gabe and I have made our return from Waterloo Canada, and the Church at War Conference; where we were able to fellowship with the likes of Pastor Tim Stephens, Jacob Raome, and Pastor James Coates, among a whole bevy of other rowdy Christians, who gave up their comforts, their careers, and sometimes, their families, for our King, Jesus Christ. Keep our brothers and sisters in Canada in your prayers as they make war against their wicked culture. Before I dive into the news: Club Membership Plug: Let’s stop and take a moment to talk about Fight Laugh Feast Club membership. By joining the Fight Laugh Feast Army, not only will you be aiding in our fight to take down secular & legacy media; but you’ll also get access to content placed in our Club Portal, such as past shows, all of our conference talks, and EXCLUSIVE content for club members that you won’t be able to find anywhere else. Lastly, you’ll also get discounts for our conferences… so if you’ve got $10 bucks a month to kick over our way, you can sign up now at fightlaughfeast.com. Now this! White House shuts down reporter's Fauci question on COVID origin: 'I'm done with you' https://youtu.be/dl77nDxM47o -Play 0:40-1:56 Whoa… order in the court ladies and gentleman! White House press secretary Karine Jean-Pierre snapped at reporters who raised questions about the origins of COVID-19 during Tuesday's press briefing, which featured outgoing White House chief medical adviser Dr. Anthony Fauci. During questions after the White House coronavirus response team updated reporters on the administration's vaccine efforts, Daily Caller White House correspondent Diana Glebova attempted to ask a question regarding what Fauci has done to investigate the origins of COVID-19. But Jean-Pierre shut Glebova down and rebuked her for speaking out of turn. Then Today News Africa journalist Simon Ateba spoke up and said her question was valid and should be asked. "You need to call people across the room. She has a valid question, she's asked about the origin of COVID," Ateba said. Fauci, who will step down as director of the National Institute of Allergy and Infectious Diseases (NIAID) in December, has faced questions from Republican lawmakers over his agency's support for coronavirus research in China. NIAID has provided millions of dollars in grant funding to EcoHealth Alliance, a nonprofit group that GOP critics claim has supported bat coronavirus research at the Wuhan Institute of Virology in China before the outbreak of the COVID-19 pandemic. Lawmakers interested in the lab-leak origins theory of COVID-19 want to probe whether that research was the genesis of the pandemic and whether Fauci played any role in approving money that was sent to the Wuhan lab. https://www.foxnews.com/politics/here-where-last-uncalled-house-races-stand-two-weeks-election-day Here is where the last uncalled House races stand two weeks from Election Day As results from midterms elections continue to trickle in two weeks past Election Day, four critical House races in Alaska, California and Colorado still remain uncalled. Fox News Digital breaks down the outstanding races and what is taking so long. California California, which has two of the four uncalled races, is a predominately vote-by-mail state, meaning every registered voter is automatically mailed a ballot 29 days prior to Election Day. With 22 million registered voters and weeks-long processing times, this means race calls can move very slowly in the Golden State. California still has 593,925 remaining ballots to be counted, according to estimates from the California Secretary of State's report on Monday. Of the unprocessed ballots remaining, about 500,000 of these ballots were mailed in Election Officials. California permits election authorities one month to complete tallying which mean voters could be waiting as late as Dec. 8 for final race outcomes. In California's 3rd Congressional District, Republican Kevin Kiley holds a commanding lead over Democrat Kermit Jones; however, approximately only a little over half of ballots have been counted in the "likely Republican" race. California accepts mail-ballots for the week following Election Day, although the ballots must be postmarked by Nov. 8. The ballots must also go through a signature verification process before being counted. The second uncalled race in California lies in the state's 13th Congressional District. This toss-up race is among the tightest remaining as Republican John Duarte narrowly leads Democrat Adam Gray by less than 800 votes. Alaska Alaska's At-Large Congressional District still remains uncalled, held up by the vote counting process of the state's newly implemented ranked-choice voting system. The seat has been rated by Fox News' Power Rankings as "lean Democratic" as a result of the ranked-choice system that gives incumbent Democrat Rep. Mary Peltola an advantage against her Republican opponents, former Gov. Sarah Palin and Nick Begich. Peltola led in the first round of the vote, with Palin in second and Begich in third, but failed to secure 50%, meaning those who voted for the candidate with the least number of votes will have their second choice vote reallocated to the other candidates until one reaches 50%. Election officials will commence the counting of second- and third-place votes Nov. 23, meaning that Alaskans may know the final outcome of the House race by end of day, if all goes as expected. Colorado: Colorado predominantly votes by mail, but processing is much swifter than California. In 2020, 90% of the vote was counted by Wednesday morning after Election Day, according to the Associated Press. Even so, mail-in ballots from out of state and overseas military service members can arrive as late as Wednesday as long as they were postmarked by Election Day. Despite relatively speedier ballot processing times, Colorado's 3rd House district still remains too close to call. Incumbent Republican Rep. Lauren Boebert was not expected to have such a close race with her Democratic opponent, Adam Frisch, in the "likely Republican" seat. The one-term congresswoman is narrowly leading the vote count by a little more than 500 votes, according to the Associated Press. Though the race qualifies for a recount under Colorado state law, Frisch conceded to Boebert on Friday. However, the Associated Press has still not called the race as of Tuesday. https://thepostmillennial.com/breaking-ap-fires-reporter-responsible-for-fake-story-alleging-russian-missiles-hit-poland?utm_campaign=64487 AP fires reporter responsible for fake story alleging Russian missiles hit Poland The Associated Press has reportedly fired journalist Jim LaPorta, who was one of two bylines that ran with the false report that Russian missiles hit Poland. The only source of that story was anonymous, which goes against AP's policy. The retracted story alleged that a senior US intelligence official said that Russian missiles "crossed into NATO member Poland, killing two people." The story was taken down the next day and replaced with an editor's note stating that the story was false and that "subsequent reporting showed that the missiles were Russian-made and most likely fired by Ukraine in defense against a Russian attack." AP's news values and principles state that there must be more than one anonymous source to run a story unless the "material comes from an authoritative figure who provides information so detailed that there is no question of its accuracy," the AP said. LaPorta wrote the article along with John Leicester, who is still working with AP. https://thenationalpulse.com/2022/11/21/gen-z-whose-votes-bolstered-democrats-in-the-mid-terms-are-suffering-massive-pandemic-induced-depression/ Gen Z – Whose Votes Bolstered Democrats in the Mid Terms – Are Suffering Massive Pandemic-Induced Depression. Millions of Gen Zers are struggling with mental health problems, according to a new survey, which reveals many of these problems were first identified during the COVID-19 pandemic. It is further evidence of the serious health consequences caused by the social-distancing measures taken in response to the virus. Generation Z is the third-largest population in America, after millennials and baby boomers. While Zoomers are often singled out for praise by the corporate media for racial and sexual diversity, it’s also becoming clear many of them are suffering mental health issues to a far greater degree than earlier generations. The survey was carried out by Harmony Healthcare IT, an Indiana-based data-management company. Just over 1000 individuals aged 18 to 24, with a roughly equal gender balance, were asked a range of detailed questions about their mental health. Forty-two percent of those surveyed said they were suffering from a diagnosed mental-health problem, with 25 percent saying their diagnosis took place during the pandemic. Anxiety, depression, attention-deficit/hyperactivity disorder (ADHD), post-traumatic stress disorder (PTSD), and bulimia were just some of the conditions the respondents reported. By comparison with millennials or Gen X-ers, Zoomers are twice as likely to report struggling with emotional distress on a daily basis. Near 70 percent said that they felt the pandemic had a negative effect on their mental health. Zoomers appear to be deeply anxious, with 85 percent saying they were worried about the future. Nine out of ten Zoomers diagnosed with a mental-health issue have anxiety and eight out of ten suffer from depression. Particular concerns for Zoomers include personal finances, the economy, their health, the environment, politics, and the workplace. Three-quarters of Zoomers say they feel disadvantaged by comparison with older generations, and 90 percent have a hard time picturing a stable future for themselves. Twenty percent of the study participants said they have a regular therapist, while 57 percent take regular medication and 39 percent attend therapy for mental health issues at least once a week. Pandemic Damage. The study is further evidence that the pandemic – in particular the social-distancing measures adopted by most governments around the world – had serious adverse consequences for the young that far outstrip any damage they might have suffered from contracting the virus. Other studies have already substantiated the mental effects of isolation and exposure to fear and uncertainty about the virus’s effects. A meta-analysis from the University of Calgary suggested that as many as one in four children worldwide are now suffering from depression and anxiety as a result of the pandemic. These unintended effects have not just been psychological. A recent study showed children are exercising less and spending more time sitting down than ever before as a result of the pandemic. Researchers at the University of Bristol revealed that fewer than four out of 10 children were doing sufficient daily exercise at the end of 2021. Obesity rates have risen at a “staggering” pace, according to the American CDC. The restrictions are even believed to have affected babies in the womb. A study based on a review of 250 babies born in New York between March and December 2020 suggested that the pandemic had serious adverse developmental effects on newborns, even if the mother had not had COVID-19 during the pregnancy. The researchers believe that increased maternal stress during pregnancy may be to blame, as well as reduced interactions with other infants and more stressful interactions with parents and caregivers. It looks like the effects of the pandemic and the overzealous responses of government “experts” will continue to ramify through the increasingly unhappy lives of our younger generations, long after COVID-19 itself becomes a distant memory. Accountable2You Is your smartphone a tool in the service of Christ, or a minefield of distractions and temptations? With soul-killing seductions just a few taps away, our families and churches must embrace biblical accountability on our digital devices. Accountable2You makes transparency easy on all your family's devices, by sharing app usage and detailed browsing history—including "Incognito" mode—with your spouse, parent, or chosen accountability partner. Accountable2You helps your family to proactively guard against temptation, so you can live with integrity for God's glory! Learn more and try it for free at Accountable2You.com/FLF Now it’s time for my favorite topic… sports! Let’s just go through some scores here for the NFL, College football, and college basketball! College Football: #14 Utah: 17 #10 Oregon: 20 #5 USC 48 #17 UCLA 45 South Carolina 63 #9 Tennessee 38 #3 Michigan 19 Illinois 17 #4 TCU 29 Baylor 28 #1 Georgia 16 Kentucky 6 How about college basketball? #10 Creighton 76 #21 Texas Tech 65 #17 SDSU 88 Ohio State 77 #14 Arizona 101 Cincinatti 93 #9 Arkansas 80 Louisville 54 (0-4) NFL: Chiefs: 30 Chargers 27 Bengals 37 Steelers 30 Cowboys 40 Vikings 3 Raiders 22 Broncos 16 Eagles 17 Colts 16 Patroits 10 Jets 3
This is Garrison Hardie with your CrossPolitic Daily Newsbrief for Wednesday, November 23, 2022. I’m back ladies and gentleman! Gabe and I have made our return from Waterloo Canada, and the Church at War Conference; where we were able to fellowship with the likes of Pastor Tim Stephens, Jacob Raome, and Pastor James Coates, among a whole bevy of other rowdy Christians, who gave up their comforts, their careers, and sometimes, their families, for our King, Jesus Christ. Keep our brothers and sisters in Canada in your prayers as they make war against their wicked culture. Before I dive into the news: Club Membership Plug: Let’s stop and take a moment to talk about Fight Laugh Feast Club membership. By joining the Fight Laugh Feast Army, not only will you be aiding in our fight to take down secular & legacy media; but you’ll also get access to content placed in our Club Portal, such as past shows, all of our conference talks, and EXCLUSIVE content for club members that you won’t be able to find anywhere else. Lastly, you’ll also get discounts for our conferences… so if you’ve got $10 bucks a month to kick over our way, you can sign up now at fightlaughfeast.com. Now this! White House shuts down reporter's Fauci question on COVID origin: 'I'm done with you' https://youtu.be/dl77nDxM47o -Play 0:40-1:56 Whoa… order in the court ladies and gentleman! White House press secretary Karine Jean-Pierre snapped at reporters who raised questions about the origins of COVID-19 during Tuesday's press briefing, which featured outgoing White House chief medical adviser Dr. Anthony Fauci. During questions after the White House coronavirus response team updated reporters on the administration's vaccine efforts, Daily Caller White House correspondent Diana Glebova attempted to ask a question regarding what Fauci has done to investigate the origins of COVID-19. But Jean-Pierre shut Glebova down and rebuked her for speaking out of turn. Then Today News Africa journalist Simon Ateba spoke up and said her question was valid and should be asked. "You need to call people across the room. She has a valid question, she's asked about the origin of COVID," Ateba said. Fauci, who will step down as director of the National Institute of Allergy and Infectious Diseases (NIAID) in December, has faced questions from Republican lawmakers over his agency's support for coronavirus research in China. NIAID has provided millions of dollars in grant funding to EcoHealth Alliance, a nonprofit group that GOP critics claim has supported bat coronavirus research at the Wuhan Institute of Virology in China before the outbreak of the COVID-19 pandemic. Lawmakers interested in the lab-leak origins theory of COVID-19 want to probe whether that research was the genesis of the pandemic and whether Fauci played any role in approving money that was sent to the Wuhan lab. https://www.foxnews.com/politics/here-where-last-uncalled-house-races-stand-two-weeks-election-day Here is where the last uncalled House races stand two weeks from Election Day As results from midterms elections continue to trickle in two weeks past Election Day, four critical House races in Alaska, California and Colorado still remain uncalled. Fox News Digital breaks down the outstanding races and what is taking so long. California California, which has two of the four uncalled races, is a predominately vote-by-mail state, meaning every registered voter is automatically mailed a ballot 29 days prior to Election Day. With 22 million registered voters and weeks-long processing times, this means race calls can move very slowly in the Golden State. California still has 593,925 remaining ballots to be counted, according to estimates from the California Secretary of State's report on Monday. Of the unprocessed ballots remaining, about 500,000 of these ballots were mailed in Election Officials. California permits election authorities one month to complete tallying which mean voters could be waiting as late as Dec. 8 for final race outcomes. In California's 3rd Congressional District, Republican Kevin Kiley holds a commanding lead over Democrat Kermit Jones; however, approximately only a little over half of ballots have been counted in the "likely Republican" race. California accepts mail-ballots for the week following Election Day, although the ballots must be postmarked by Nov. 8. The ballots must also go through a signature verification process before being counted. The second uncalled race in California lies in the state's 13th Congressional District. This toss-up race is among the tightest remaining as Republican John Duarte narrowly leads Democrat Adam Gray by less than 800 votes. Alaska Alaska's At-Large Congressional District still remains uncalled, held up by the vote counting process of the state's newly implemented ranked-choice voting system. The seat has been rated by Fox News' Power Rankings as "lean Democratic" as a result of the ranked-choice system that gives incumbent Democrat Rep. Mary Peltola an advantage against her Republican opponents, former Gov. Sarah Palin and Nick Begich. Peltola led in the first round of the vote, with Palin in second and Begich in third, but failed to secure 50%, meaning those who voted for the candidate with the least number of votes will have their second choice vote reallocated to the other candidates until one reaches 50%. Election officials will commence the counting of second- and third-place votes Nov. 23, meaning that Alaskans may know the final outcome of the House race by end of day, if all goes as expected. Colorado: Colorado predominantly votes by mail, but processing is much swifter than California. In 2020, 90% of the vote was counted by Wednesday morning after Election Day, according to the Associated Press. Even so, mail-in ballots from out of state and overseas military service members can arrive as late as Wednesday as long as they were postmarked by Election Day. Despite relatively speedier ballot processing times, Colorado's 3rd House district still remains too close to call. Incumbent Republican Rep. Lauren Boebert was not expected to have such a close race with her Democratic opponent, Adam Frisch, in the "likely Republican" seat. The one-term congresswoman is narrowly leading the vote count by a little more than 500 votes, according to the Associated Press. Though the race qualifies for a recount under Colorado state law, Frisch conceded to Boebert on Friday. However, the Associated Press has still not called the race as of Tuesday. https://thepostmillennial.com/breaking-ap-fires-reporter-responsible-for-fake-story-alleging-russian-missiles-hit-poland?utm_campaign=64487 AP fires reporter responsible for fake story alleging Russian missiles hit Poland The Associated Press has reportedly fired journalist Jim LaPorta, who was one of two bylines that ran with the false report that Russian missiles hit Poland. The only source of that story was anonymous, which goes against AP's policy. The retracted story alleged that a senior US intelligence official said that Russian missiles "crossed into NATO member Poland, killing two people." The story was taken down the next day and replaced with an editor's note stating that the story was false and that "subsequent reporting showed that the missiles were Russian-made and most likely fired by Ukraine in defense against a Russian attack." AP's news values and principles state that there must be more than one anonymous source to run a story unless the "material comes from an authoritative figure who provides information so detailed that there is no question of its accuracy," the AP said. LaPorta wrote the article along with John Leicester, who is still working with AP. https://thenationalpulse.com/2022/11/21/gen-z-whose-votes-bolstered-democrats-in-the-mid-terms-are-suffering-massive-pandemic-induced-depression/ Gen Z – Whose Votes Bolstered Democrats in the Mid Terms – Are Suffering Massive Pandemic-Induced Depression. Millions of Gen Zers are struggling with mental health problems, according to a new survey, which reveals many of these problems were first identified during the COVID-19 pandemic. It is further evidence of the serious health consequences caused by the social-distancing measures taken in response to the virus. Generation Z is the third-largest population in America, after millennials and baby boomers. While Zoomers are often singled out for praise by the corporate media for racial and sexual diversity, it’s also becoming clear many of them are suffering mental health issues to a far greater degree than earlier generations. The survey was carried out by Harmony Healthcare IT, an Indiana-based data-management company. Just over 1000 individuals aged 18 to 24, with a roughly equal gender balance, were asked a range of detailed questions about their mental health. Forty-two percent of those surveyed said they were suffering from a diagnosed mental-health problem, with 25 percent saying their diagnosis took place during the pandemic. Anxiety, depression, attention-deficit/hyperactivity disorder (ADHD), post-traumatic stress disorder (PTSD), and bulimia were just some of the conditions the respondents reported. By comparison with millennials or Gen X-ers, Zoomers are twice as likely to report struggling with emotional distress on a daily basis. Near 70 percent said that they felt the pandemic had a negative effect on their mental health. Zoomers appear to be deeply anxious, with 85 percent saying they were worried about the future. Nine out of ten Zoomers diagnosed with a mental-health issue have anxiety and eight out of ten suffer from depression. Particular concerns for Zoomers include personal finances, the economy, their health, the environment, politics, and the workplace. Three-quarters of Zoomers say they feel disadvantaged by comparison with older generations, and 90 percent have a hard time picturing a stable future for themselves. Twenty percent of the study participants said they have a regular therapist, while 57 percent take regular medication and 39 percent attend therapy for mental health issues at least once a week. Pandemic Damage. The study is further evidence that the pandemic – in particular the social-distancing measures adopted by most governments around the world – had serious adverse consequences for the young that far outstrip any damage they might have suffered from contracting the virus. Other studies have already substantiated the mental effects of isolation and exposure to fear and uncertainty about the virus’s effects. A meta-analysis from the University of Calgary suggested that as many as one in four children worldwide are now suffering from depression and anxiety as a result of the pandemic. These unintended effects have not just been psychological. A recent study showed children are exercising less and spending more time sitting down than ever before as a result of the pandemic. Researchers at the University of Bristol revealed that fewer than four out of 10 children were doing sufficient daily exercise at the end of 2021. Obesity rates have risen at a “staggering” pace, according to the American CDC. The restrictions are even believed to have affected babies in the womb. A study based on a review of 250 babies born in New York between March and December 2020 suggested that the pandemic had serious adverse developmental effects on newborns, even if the mother had not had COVID-19 during the pregnancy. The researchers believe that increased maternal stress during pregnancy may be to blame, as well as reduced interactions with other infants and more stressful interactions with parents and caregivers. It looks like the effects of the pandemic and the overzealous responses of government “experts” will continue to ramify through the increasingly unhappy lives of our younger generations, long after COVID-19 itself becomes a distant memory. Accountable2You Is your smartphone a tool in the service of Christ, or a minefield of distractions and temptations? With soul-killing seductions just a few taps away, our families and churches must embrace biblical accountability on our digital devices. Accountable2You makes transparency easy on all your family's devices, by sharing app usage and detailed browsing history—including "Incognito" mode—with your spouse, parent, or chosen accountability partner. Accountable2You helps your family to proactively guard against temptation, so you can live with integrity for God's glory! Learn more and try it for free at Accountable2You.com/FLF Now it’s time for my favorite topic… sports! Let’s just go through some scores here for the NFL, College football, and college basketball! College Football: #14 Utah: 17 #10 Oregon: 20 #5 USC 48 #17 UCLA 45 South Carolina 63 #9 Tennessee 38 #3 Michigan 19 Illinois 17 #4 TCU 29 Baylor 28 #1 Georgia 16 Kentucky 6 How about college basketball? #10 Creighton 76 #21 Texas Tech 65 #17 SDSU 88 Ohio State 77 #14 Arizona 101 Cincinatti 93 #9 Arkansas 80 Louisville 54 (0-4) NFL: Chiefs: 30 Chargers 27 Bengals 37 Steelers 30 Cowboys 40 Vikings 3 Raiders 22 Broncos 16 Eagles 17 Colts 16 Patroits 10 Jets 3
Strawberries could help reduce harmful inflammation in the colon University of Massachusetts, August 20, 202 Inflammatory bowel disease (IBD) is a set of painful conditions that can cause severe diarrhea and fatigue. Treatments can include medications and surgery. But now researchers report that a simple dietary intervention could mitigate colonic inflammation and improve gut health. In this case, a strawberry—or rather, less than a cupful of strawberries—a day could help keep the doctor away. The dietary consumption of fruits and vegetables has been associated with a lowered risk of IBD. To establish an effective and practical approach to decrease colonic inflammation in both IBD patients and the general population, Xiao and his team at the University of Massachusetts Amherst focused on strawberries due to their wide consumption. The researchers found that dietary consumption of whole strawberries at a dose equivalent to as low as three-quarters of a cup of strawberries per day in humans significantly suppressed symptoms like body weight loss and bloody diarrhea in mice with IBD. Strawberry treatments also diminished inflammatory responses in the mice's colonic tissue. But decreased inflammation wasn't the strawberry's only conferred benefit during this study. Following the dietary treatments of whole strawberries, the researchers observed a reversal of that unhealthy microbiota composition in the IBD mice. Xiao's team also obtained experimental data that indicated strawberries might impact abnormal metabolic pathways in the IBD mice, which in turn could lead to the decreased colonic inflammation they observed. Higher diet quality relates to decelerated epigenetic aging Tufts University, August 1, 2022 DNA methylation–based epigenetic age measures have been used as biological aging markers and are associated with a healthy lifespan. Few population-based studies have examined the relation between diet and epigenetic age acceleration. We aimed to investigate the relation between diet quality and epigenetic age acceleration. We analyzed data from 1995 participants (mean age, 67 years; 55% women) of the Framingham Heart Study Offspring Cohort. Cross-sectional associations between the Dietary Approaches to Stop Hypertension (DASH) score and 3 whole-blood DNA methylation–derived epigenetic age acceleration measures—Dunedin Pace of Aging Methylation (DunedinPoAm), GrimAge acceleration (GrimAA), and PhenoAge acceleration (PhenoAA)—were examined. Conclusions: Higher diet quality is associated with slower epigenetic age acceleration, which partially explains the beneficial effect of diet quality on the lifespan. Our findings emphasize that adopting a healthy diet is crucial for maintaining healthy aging. Feeling anxious or blue? Ultra-processed foods may be to blame Florida Atlantic University, August 25, 2022 Do you love those sugary-sweet beverages, reconstituted meat products and packaged snacks? You may want to reconsider based on a new study that explored whether individuals who consume higher amounts of ultra-processed food have more adverse mental health symptoms. Researchers from Florida Atlantic University's Schmidt College of Medicine and collaborators explored a nationally representative sample of the United States population to determine if individuals who consume high amounts of ultra-processed foods report significantly more adverse mental health symptoms including depression, anxiety and mentally unhealthy days. They measured mild depression, number of mental unhealthy days and number of anxious days in 10,359 adults 18 and older from the U.S. National Health and Nutrition Examination Survey. Results of the study, published in the journal Public Health Nutrition, showed that individuals who consumed the most ultra-processed foods as compared with those who consumed the least amount had statistically significant increases in the adverse mental health symptoms of mild depression, "mentally unhealthy days" and "anxious days." They also had significantly lower rates of reporting zero "mentally unhealthy days" and zero "anxious days." Findings from this study are generalizable to the entire U.S. as well as other Western countries with similar ultra-processed food intakes. Many types of leisure time activities may lower risk of death for older adults National Cancer Institute, August 25, 2022 Older adults who participate weekly in many different types of leisure time activities, such as walking for exercise, jogging, swimming laps, or playing tennis, may have a lower risk of death from any cause, as well as death from cardiovascular disease and cancer, according to a new study led by researchers at the National Cancer Institute, part of the National Institutes of Health. The findings suggest that it's important for older adults to engage in leisure time activities that they enjoy and can sustain, because many types of these activities may lower the risk of death, the authors wrote. Using data from 272,550 adults between the ages of 59 and 82 who had completed questionnaires about their leisure-time activities as part of the NIH-AARP Diet and Health Study, the researchers looked at whether participating in equivalent amounts of seven different exercise and recreational activities—including running, cycling, swimming, other aerobic exercise, racquet sports, golf, and walking for exercise—was associated with lowered risk of death. The researchers found that achieving the recommended amount of physical activity per week through any combination of these activities was associated with a 13% lower risk of death from any cause compared with no participation in these activities. When they looked at the role of each activity individually, playing racquet sports was associated with a 16% reduction in risk and running with a 15% reduction. However, all the activities investigated were similarly associated with lower risks of death. The levels of activity by the most active individuals (those who exceeded the recommended levels of physical activity) were associated with even greater reductions in the risk of death, but there were diminishing returns as activity levels increased. Even people who did some recreational activity, though less than the recommended amount, had a 5% reduction in risk of death than those who did not participate in any of the activities studied. These activities were also associated with a lower risk of death from cardiovascular disease and cancer. Playing racquet sports was associated with the greatest reduction in risk of cardiovascular deaths (27% reduction), while running was associated with the greatest reduction in risk of cancer deaths (19% reduction). Avocado may resist the effects of leukemia University of Waterloo (Canada), August 19, 2022 One of the many health benefits avocados offer is their ability to ward off cancer. Avocados contain avocatin B, which is a compound found to fight against a type of leukemia called acute myeloid leukemia (AML), according to a study carried out by a researcher from the University of Waterloo, Canada. AML is known by many names, like acute myelocytic leukemia, acute myelogenous leukemia, acute granulocytic leukemia, and acute non-lymphocytic leukemia. AML is a type of blood cancer that is most common in older people. Approximately 90 percent of people with this type of cancer die within five years of diagnosis. In the in vitro study, Canadian researcher Paul Spagnuolo found that avocatin B fights AML by targeting leukemia stem cells – which are the root of the disease – without harming healthy, non-cancerous cells. This indicated that the compound is both effective against AML and not toxic to the body. Avocados can also fight against prostate and oral cancer cells. Researchers from the University of California, Los Angeles conducted a review of studies on the potential health benefits of avocados and looked at evidence that specific avocado extracts can inhibit the growth of prostate cancer cells and oral cancer cells. They found that the active compounds in avocados make them potentially beneficial for preventing cancer. News addiction is linked to not only poor mental well-being but physical health too, new study Texas Tech University, August 25, 2022 People with an obsessive urge to constantly check the news are more likely to suffer from stress, anxiety, and physical ill health, finds a new study published in the peer-reviewed journal Health Communication. For many people, reading bad news can make us feel temporarily powerless and distressed. For others, being exposed to a 24-hour news cycle of continually evolving events can have serious impacts on mental and physical well-being—as these new findings, out today, show, with those who have a high-levels of news addiction reporting "significantly greater physical ill-being." "Witnessing these events unfold in the news can bring about a constant state of high alert in some people, kicking their surveillance motives into overdrive and making the world seem like a dark and dangerous place," says Bryan McLaughlin, associate professor of advertising at the College of Media and Communication at Texas Tech University. "For these individuals, a vicious cycle can develop, in which rather than tuning out, they become drawn further in, obsessing over the news and checking for updates around the clock to alleviate their emotional distress. But it doesn't help, and the more they check the news, the more it begins to interfere with other aspects of their lives." To study this phenomenon, McLaughlin and his colleagues, analyzed data from an online survey of 1,100 US adults. The results revealed that 16.5% of people surveyed showed signs of "severely problematic" news consumption. Such individuals frequently became so immersed and personally invested in news stories that the stories dominated the individual's waking thoughts, disrupted time with family and friends, made it difficult to focus on school or work, and contributed to restlessness and an inability to sleep. 73.6% of those recognized to have severe levels of problematic news consumption reported experiencing mental ill-being "quite a bit" or "very much"—while frequent symptoms were only reported by 8% of all other study participants. 61% of those with severe levels of problematic news reported experiencing physical ill-being "quite a bit" or "very much" compared to only 6.1% for all other study participants. According to McLaughlin, the findings show that there is a need for focused media literacy campaigns to help people develop a healthier relationship with the news.
Dr. Alexander Lanoszka, an assistant professor of International Relations at the University of Waterloo (Canada) talks about the military alliances around Ukraine and Russia. -- Support this podcast by donating to PayPal.me/MrKovalenko. -- Sound from Zapsplat.com --- Support this podcast: https://anchor.fm/viktor-kovalenko-podcast/support
Videos: 1. The great recycling LIE (what really happens to plastic) (10:44) 2. Is It Game Over? New NASA Report (5:30) 2. You won't believe what Justin Trudeau's government just did | Redacted with Clayton Morris (13:26) 3. Neil Oliver – Who pulls the strings – Pandemic Treaty, Wealth & Power? (2:00) 4. He's EXPOSING the truth in Syria and they don't like it | Redacted conversation w/ Kevork Almassian (first 10:00) 5. Russian Ruble now best performing currency in the world this year… another example of how US sanctions have failed. 6. Vanessa Beeley and Eva Bartlett are smeared by the Guardian for reporting the truth (3:07) 7. Kim Iversen: Inside The SECRET Bilderberg Meetings Between Spies, War Hawks And World Leaders (9:28) 8. New Rule: The Misinformation Age | Real Time with Bill Maher (HBO) 9. https://theduran.locals.com/post/2311112/title 10. https://www.youtube.com/watch?v=3maIN4-ZJl8 Strawberry Compound Shown to Protect Against Alzheimer's, Memory Loss Salk Institute for Biological Studies, June 16, 2022 The thought of losing your mind is a frightening one, but one in three Americans die with Alzheimer's or some other form of dementia. Regardless how frightening the possibility is, the chances of it happening to you aren't exactly slim, which means prevention should be at the forefront of your mind. A recent study from the Salk Institute for Biological Studies indicates prevention could be as simple as a natural foods diet—rich in fruits (such as strawberries) and vegetables containing something called fisetin. Fisetin is a flavonol found in strawberries, mangoes, cucumbers, and other vegetables and fruits. Researchers with the Salk Institute found this simple compound can actually reduce the risk of Alzheimer's in mice, and could be effective in humans as well. Maher and her team have documented that fisetin has both anti-inflammatory and antioxidant properties in the brain. It is also able to turn on a cellular pathway related to memory function. The team looked to a type of mouse with mutated genes making them vulnerable to Alzheimer's. At three months old, the researchers began feeding the mice a diet enriched with fisetin. Mice who hadn't received the fisetin began struggling in the mazes at nine months of age, but the fisetin mice performed as well as normal (non-predisposed) mice at both nine and twelve months of age. Avocados may hold the answer to beating leukemia University of Waterloo (Canada), June 16, 2022 Rich, creamy, nutritious and now cancer fighting. New research reveals that molecules derived from avocados could be effective in treating a form of cancer. Professor Paul Spagnuolo from the University of Waterloo has discovered a lipid in avocados that combats acute myeloid leukemia (AML) by targeting the root of the disease – leukemia stem cells. Worldwide, there are few drug treatments available to patients that target leukemia stem cells. “The stem cell is really the cell that drives the disease,” said Professor Spagnuolo, in Waterloo's School of Pharmacy. “The stem cell is largely responsible for the disease developing and it's the reason why so many patients with leukemia relapse. We've performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed.” Inability to stand on one leg for 10 seconds in mid to later life linked to near doubling in risk of death Exercise Medicine Clinic-CLINIMEX (Brazil) and University of Eastern Finland, June 21, 2022 The inability to stand on one leg for 10 seconds in mid- to later life is linked to a near doubling in the risk of death from any cause within the next 10 years, finds research published online in the British Journal of Sports Medicine This simple and safe balance test could be included in routine health checks for older adults, say the researchers. The researchers wanted to find out whether a balance test might be a reliable indicator of a person's risk of death from any cause within the next decade, and, as such, might therefore merit inclusion in routine health checks in later life. Participants were asked to stand on one leg for 10 seconds without any additional support. To improve standardization of the test, participants were asked to place the front of the free foot on the back of the opposite lower leg, while keeping their arms by their sides and their gaze fixed straight ahead. Up to three attempts on either foot were permitted. In all, around 1 in 5 (20.5%; 348) participants failed to pass the test. The inability to do so rose in tandem with age, more or less doubling at subsequent 5 year intervals from the age of 51-55 onwards. The proportions of those unable to stand on one leg for 10 seconds were: nearly 5% among 51-55 year-olds; 8% among 56-60 year-olds; just under 18% among 61-65 year-olds; and just under 37% among 66-70 year-olds. More than half (around 54%) of those aged 71-75 were unable to complete the test. In other words, people in this age group were more than 11 times as likely to fail the test as those just 20 years younger. During an average monitoring period of 7 years, 123 (7%) people died: cancer (32%); cardiovascular disease (30%); respiratory disease (9%); and COVID-19 complications (7%). The proportion of deaths among those who failed the test was significantly higher: 17.5% vs. 4.5%, reflecting an absolute difference of just under 13%. Anxious Children have Bigger “Fear Centers” in the Brain Stanford University School of Medicine, June 16, 2022 The amygdala is a key “fear center” in the brain. Alterations in the development of the amygdala during childhood may have an important influence on the development of anxiety problems, reports a new study in the current issue of Biological Psychiatry. Researchers at the Stanford University School of Medicine recruited 76 children, 7 to 9 years of age, a period when anxiety-related traits and symptoms can first be reliably identified. The researchers found that children with high levels of anxiety had enlarged amygdala volume and increased connectivity with other brain regions responsible for attention, emotion perception, and regulation, compared to children with low levels of anxiety. They also developed an equation that reliably predicted the children's anxiety level from the MRI measurements of amygdala volume and amygdala functional connectivity. The most affected region was the basolateral portion of the amygdala, a subregion of the amygdala implicated in fear learning and the processing of emotion-related information. Our study represents an important step in characterizing altered brain systems and developing predictive biomarkers in the identification for young children at risk for anxiety disorders,” Qin said. New research: Olive oil compound destroys cancer cells in 30 minutes Rutgers University & Hunter College, June 12, 2022 Oleocanthal, a polyphenolic, therapeutic compound found in olive oil is the subject of a new anti-cancer study performed by nutritional science and cancer biology researchers with The School of Environmental and Biological Sciences at Rutgers and Hunter's College in New York City. Programmed cell death, known as apoptosis takes approximately 16-24 hours. Dynamic new research just published in the Journal of Molecular and Cellular Oncology blew scientists away – when exposed to oleocanthal, a polyphenol compound found in olive oil, cancerous cells died within 30 minutes to an hour. While researchers previously understood that compounds in olive oil were capable of killing cancer cells, until now, such short apoptosis had not been observed. Even more fascinating was when the team looked closely to surmise why apoptosis was occurring under such swift circumstances – they discovered that cancer cells were being killed by their own enzymes. And, not only one isolated type of cancerous cell, but all of the cancerous cells they were examining. Unlike chemotherapeutic pharmaceuticals that devastate healthy cellular activity, the therapeutic polyphenolic compound found in olive oil kills cancer while maintaining vitality among healthy cells. As Paul Breslin, one of the study's authors at Rutgers noted, while cancerous cells died, healthy cells were not harmed, but rather the oleocanthal “put them to sleep.” The lifecycle of healthy cells was only temporarily affected in this way, without any negative observations and in approximately 24 hours, the healthy cells resumed their life cycle. Sports, not screens: The key to happier, healthier children University of South Australia, June 21, 2022 Whether it's sports practice, music lessons or a casual catch up with friends, when children are involved in after-school activities, they're more likely to feel happier and healthier than their counterparts who are glued to a screen. In a new study conducted by the University of South Australia, researchers found that children's well-being is heightened when they participate in extra-curricular activities, yet lowered when they spent time on social media or playing video games. Published in BMC Pediatrics, the study analyzed data from 61,759 school students in years 4 to 9, assessing the average number of days per week children participated in after-school activities (3–6pm), and measure these against well-being factors—happiness, sadness, worry, engagement, perseverance, optimism, emotion regulation, and life satisfaction. It found that most students watched TV about four days of the school week and spent time on social media about three days of the week. Our study highlights how some out-of-school activities can boost children's well-being, while others—particularly screens—can chip away at their mental and physical health. “Screens are a massive distraction for children of all ages. And whether children are gaming, watching TV or on social media, there's something about all screens that's damaging to their well-being. Students in lower socio-economic backgrounds who frequently played sports were 15% more likely to be optimistic, 14% more likely to be happy and satisfied with their life, and 10% more likely to be able to regulate their emotions. Conversely, children who played video games and used social media almost always had lower levels of well-being: up to 9% less likely to be happy, up to 8% to be less optimism and 11% to be more likely to give up on things.
We were lucky enough to be joined by Oregon Duck Izzy to talk about her inspiring story of being a walk on exchange student at University of Waterloo Canada to getting a scholarship at Oregon! We also dive into what life has been like as a US Collegiate athlete and her aspirations for the future.
In 2021, the Intergovernmental Panel on Climate Change released a report that outlined how climate change is now widespread, rapid, and intensifying. So at this point, is travel is an unnecessary privilege that is worsening our climate situation? Or, is there a way to strike a balance between travel and sustainability? Erin is joined by Dr. Daniel Scott to unpack these difficult questions. GUEST: Dr. Daniel Scott, University Research Chair in Climate and Society in the Geography and Environmental Management as well as the Director of the Interdisciplinary Center on Climate Change at the University of Waterloo (Canada). RESOURCES: World Tourism Day SUPPORT US ON PATREON for as little as $5 a month! THANK YOU TO OUR SPONSOR, WORLD NOMADS! Inspiration, opportunities and travel insurance to help you fuel your curiosity, find your journey and travel bravely. @worldnomads Check out www.worldnomads.com. Benefits limits, conditions and exclusions apply. Be sure to read your policy wording. HOW TO SUPPORT US: Alpaca My Bags is the podcast that is creating a platform for discussing travel through a critical lens and responsible travel. If you're a fan of the podcast, don't forget to subscribe, rate and review Alpaca My Bags! SUPPORT US ON PATREON for as little as $5 a month. ALSO, we're looking for more info on what you like and dislike about the podcast, and how you found us! If you have one minute today, please fill out this quick survey for us! Follow us on social media @alpacamybagspod. CREDITS Written and Hosted by: Erin Hynes Producer: Kattie Laur Music from Motion Array Logo by Christopher McCluskey
When you think about how the universe works, most people start from the cosmic perspective, but what about the little guys? Literally! This week we talk to Dr Chris Ferrie about what quantum physics brings to our understanding of the universe and how things work. Expert guest: Chris Ferrie is an Associate Professor at the University of Technology Sydney and the Centre for Quantum Software and Information. His research interests include quantum learning and control. He obtained his PhD in Applied Mathematics from the Institute for Quantum Computing and University of Waterloo (Canada) in 2012. Chris's passion for communicating science has led from the most esoteric topics of mathematical physics to more recently writing children's books, such as Quantum Physics for Babies, and a whole collection of other titles that make science accessible even for the youngest children. His latest book – Where did the universe come from? And other cosmic questions – explores how the connection between the quantum and cosmos provides our understanding of the universe. You can find Chris online at csferrie.com.Comedy guest: David Rose is a stand up comedian and writer based in Melbourne, Australia. His solo work has been featured on the Australian Broadcasting Commission (ABC)'s Radio National, as well as ABC TV's Tonightly. His comedy has generated millions of views across YouTube, TikTok, Facebook and Reddit and he has opened for internationally renowned comedians across the world. David is currently performing in the U.S.A, he takes no responsibility for the current state of America. You can find David on Instagram and TikTok
HEALTH NEWS Adding herbs and spices to meals may help lower blood pressure Texas Tech University, November 8, 2021 In a controlled-feeding study, the researchers found that seasoning foods with 6.5 grams, or about 1.3 teaspoons, of herbs and spices a day was linked with lower blood pressure after four weeks. The findings offer people a simple way to help improve their heart health. For the study, the researchers recruited 71 people with risk factors for heart disease. Every participant consumed every spice diet—one low, one moderate, and one high in herbs and spices—in a random order for four weeks each, with a two-week break between each diet period. Blood samples were drawn from each participant at the beginning of the study as well as after each diet period. The doses included a blend of 24 different herbs and spices, ranging from basil and thyme to cinnamon and turmeric, designed to simulate the way people use different herbs and spices throughout the day while cooking. The researchers found that after consuming the diet including a high dose of herbs and spices, participants had lower systolic blood pressure than after the diet with the medium dose. Participants also had lower diastolic blood pressure after the diet with a high dose of herbs and spices than after the diet with a low dose. Bitter melon can lower blood sugar levels and even prevent cancer University of Colorado Cancer Center, November 11, 2021 Bitter melon (Momordica charantia), also known as bitter gourd and balsam pear in other parts of the world, is one of those foods that meet more than your senses of sight and taste. A study conducted by researchers from the University of Colorado Cancer Center demonstrated the vegetable's ability to fight pancreatic cancer, one of the hardest cancers to treat. It found that treating pancreatic cancer tumors in mice with 5 milligrams of freeze-dried bitter melon juice every day reduces the tumors' size and makes them 64 percent smaller than those in untreated mice. What more, bitter melon proved more effective than a common chemotherapy drug used in a similar study, which reduced the tumor size by only 52 percent. The researchers noted that the dosage used in the study caused no adverse effects on the mice and may be adapted for human consumption. In another study, bitter melon caused apoptosis – cellular death – in four pancreatic cancer cell lines, reducing the viability of two lines by 90 percent and the other two by an impressive 98 percent. It also halted the metastasis and re-growth of the cancer cells. Further research has shown the vegetable's activity against other types of cancer as well, including blood, colon, liver, stomach, and breast cancers. If you really don't think you can take the vegetable's flavor, you can take it in capsule form. Do note that some studies showing its benefits for blood sugar control used dosages as high as 2,000 mg a day. To ensure that bitter melon supplements are the best for your condition, it would be best to consult with your healthcare provider before taking them. Flame retardants linked to autistic-like behavior University of California at Riverside, November 7, 2021 Polybrominated diphenyl ethers, or PBDEs, are a class of fire-retardant chemicals that are ubiquitous. They are found on upholstery, carpets, curtains, electronics, and even infant products. Flame retardants migrate out of products into dust that humans contact and can ingest. Considered to be global environmental pollutants, they have been detected in water, soil, air, food products, animals, and human tissues. They are found, too, in breast milk of women all over the world. A research team has found that when female mice exposed to PBDEs pass on these neuroendocrine-disrupting chemicals to their developing offspring, the female offspring show traits relevant to autism spectrum disorders, or ASD. Their short-term social-recognition ability and long-term social memory is reduced significantly and the offspring show exaggerated “marble burying” behavior — repetitive behavior reminiscent of human compulsive behavior, a core symptom of ASD. “Humans mostly rely on faces to recognize people and most autistics show deficits in face-identity processing,” Curras-Collazo explained. “Mice, on the other hand, rely on smell for social recognition. The female offspring of mother mice exposed to PBDEs showed olfactory deficits that dampened their ability to recognize other mice. In effect, these offspring do not distinguish new mice from familiar ones. Humans with ASD also show abnormal olfactory ability.” To the authors' knowledge, their study is the first to show autistic-relevant behavior and brain changes in female offspring from maternal transfer of environmental pollutants. The behaviors were also tested in exposed mothers, but they were largely unaffected. ype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE‑71.” Two omega-3s in fish oil may boost brain function in people with heart disease Harvard Medical School , November 8, 2021 Two omega-3 fatty acids found in fish oil may help improve brain function in older adults who have a type of heart disease known to put people at risk for cognitive decline. A new study found that DHA and EPA, given in a combined supplement at prescription levels, improved cognitive function in older adults with coronary artery disease, or CAD. It is a common type of heart disease that occurs when plaque builds up in the arteries and hinders proper blood flow. Studies have shown people with CAD have a 45% increased risk for cognitive decline. The largest improvements in brain function were seen when higher levels of both types of omega-3 fatty acids were present in the bloodstream. When analyzed individually, DHA levels were a better predictor for cognitive improvement than EPA, suggesting the presence of one type of omega-3 fatty acid was more important than the other, the authors concluded. "The study showed EPA adds additional benefit when DHA levels are already high," said study researcher Dr. Francine Welty, an associate professor of medicine at Harvard Medical School in Boston. "But EPA levels alone had no predictive ability for cognitive improvement." Despite understanding the concept of mindfulness, people are applying it incorrectly, research finds University of Waterloo (Canada), November 8, 2021 Mindful awareness is about both accepting and engaging with life's challenges, and that's what popularized concepts of mindfulness tend to miss, new research has found. Studying popular concepts of mindfulness, the researchers found most laypeople are confusing the practice with passive acceptance of problem—a misconception scientists say ignores the important work of engaging with them. Originating in Buddhist religious practice, much of the mindfulness movement's popularity grew from clinical research affirming its potential for reducing stress and related health disorders. It is, in fact, the engagement with stressors that ultimately results in stress relief. More specifically, mindfulness includes two main dimensions: awareness and acceptance. "While we found that people seem to conceptually understand that mindfulness involves engagement, the general public is not walking the talk. Our results suggest that laypeople may understand what awareness is, but the next step of acceptance may not be well understood—limiting potential for engaging with problems," said Ellen Choi, lead author on the paper. Bacterial pneumonia far more dangerous to the heart than viral pneumonia, study finds Intermountain Medical Center (Utah), November 11, 2021 Heart complications in patients diagnosed with bacterial pneumonia are more serious than in patients diagnosed with viral pneumonia, according to new research. In the study of nearly 5,000 patients, researchers found that patients diagnosed with bacterial pneumonia had a 60 percent greater risk of a heart attack, stroke, or death than patients who had been diagnosed with viral pneumonia. "We've always known pneumonia was a risk factor for a major adverse cardiac event, like a heart attack, within the first 90 days of being diagnosed," said J. Brent Muhlestein, MD, a cardiovascular researcher with the Intermountain Heart Institute at Intermountain Medical Center. "What we didn't know was which type of pneumonia was more dangerous. The results of this study provided a clear answer, which will allow physicians to better monitor patients and focus on reducing their risk of a major adverse cardiac event." Nearly 80 percent of the patients were diagnosed with bacterial pneumonia, and 34 percent (1,270 patients) of them had a major cardiovascular event within 90 days. At the same time, 21 percent of the patients were diagnosed with viral pneumonia, and 26 percent (258 patients) had a major adverse event within the 90-day window. "The likely underlying cause is that bacterial pneumonia causes greater inflammation of the arteries compared to viral pneumonia," said Dr. Muhlestein. Researchers find exposure to microplastics may alter cellular function Florida State University, November 11, 2021 Pollution from miniscule pieces of plastic, or microplastics, have been a growing concern for scientists, public health advocates and environmentalists as these nondegradable items have increasingly made their way into waterways and even the air we breathe. Now, a team researchers found that exposure to microplastics for only a few days caused human lung cells to slow down their metabolism and growth, change shapes, and decluster so that gaps exist in what is typically a solid sheet of cells. The findings raise questions about the long-term effects of microplastics on human health, particularly for those who already have respiratory conditions. The team exposed lung cells in a petri dish to small amounts of polystyrene at levels that are commonly found in the environment and found that though the plastic didn't cause cell death, it caused some interesting changes. After only a few days, they found that the cell's metabolic processes had slowed down, cell proliferation was inhibited, the shape of the cell morphed and the delustering had occurred. Additionally, the team found that the microplastic particles were uptaken by the cells and had formed a ring around the nucleus in the cell.
Natural compound in basil may protect against Alzheimer's disease pathology University of South Florida, October 5, 2021 Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer's disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests. The new study published Oct. 5 in the Frontiers in Aging Neuroscience, discovered a sensing mechanism associated with the gut microbiome that explains how fenchol reduces neurotoxicity in the Alzheimer's brain. Emerging evidence indicates that short-chain fatty acids (SCFAs)– metabolites produced by beneficial gut bacteria and the primary source of nutrition for cells in your colon—contribute to brain health. The abundance of SCFAs is often reduced in older patients with mild cognitive impairment and Alzheimer's disease, the most common form of dementia. However, how this decline in SCFAs contributes to Alzheimer's disease progression remains largely unknown. Gut-derived SCFAs that travel through the blood to the brain can bind to and activate free fatty acid receptor 2 (FFAR2), a cell signaling molecule expressed on brain cellscalled neurons. "Our study is the first to discover that stimulation of the FFAR2 sensing mechanism by these microbial metabolites (SCFAs) can be beneficial in protecting brain cells against toxic accumulation of the amyloid-beta (Aβ) protein associated with Alzheimer's disease," said principal investigator Hariom Yadav, Ph.D., professor of neurosurgery and brain repair at the USF Health Morsani College of Medicine, where he directs the USF Center for Microbiome Research. One of the two hallmark pathologies of Alzheimer's disease is hardened deposits of Aβ that clump together between nerve cells to form amyloid protein plaques in the brain. The other is neurofibrillary tangles of tau protein inside brain cells. These pathologies contribute to the neuron loss and death that ultimately cause the onset of Alzheimer's, a neurodegenerative disease characterized by loss of memory, thinking skills and other cognitive abilities. Dr. Yadav and his collaborators delve into molecular mechanisms to explain how interactions between the gut microbiome and the brain might influence brain health and age-related cognitive decline. In this study, Dr. Yadav said, the research team set out to uncover the "previously unknown" function of FFAR2 in the brain. The researchers first showed that inhibiting the FFAR2 receptor (thus blocking its ability to "sense" SCFAs in the environment outside the neuronal cell and transmit signaling inside the cell) contributes to the abnormal buildup of the Aβ protein causing neurotoxicity linked to Alzheimer's disease. Then, they performed large-scale virtual screening of more than 144,000 natural compounds to find potential candidates that could mimic the same beneficial effect of microbiota produced SCFAs in activating FFAR2 signaling. Identifying a natural compound alternative to SCFAs to optimally target the FFAR2 receptor on neurons is important, because cells in the gut and other organs consume most of these microbial metabolites before they reach the brain through blood circulation, Dr. Yadav noted. Dr. Yadav's team narrowed 15 leading compound candidates to the most potent one. Fenchol, a plant-derived compound that gives basil its aromatic scent, was best at binding to the FFAR's active site to stimulate its signaling. Further experiments in human neuronal cell cultures, as well as Caenorhabditis (C.) elegans (worm) and mouse models of Alzheimer's disease demonstrated that fenchol significantly reduced excess Aβ accumulation and death of neurons by stimulating FFAR2 signaling, the microbiome sensing mechanism. When the researchers more closely examined how fenchol modulates Aβ-induced neurotoxicity, they found that the compound decreased senescent neuronal cells, also known as "zombie" cells, commonly found in brains with Alzheimer's disease pathology. Zombie cells stop replicating and die a slow death. Meanwhile, Dr. Yadav said, they build up in diseased and aging organs, create a damaging inflammatory environment, and send stress or death signals to neighboring healthy cells, which eventually also change into harmful zombie cells or die. "Fenchol actually affects the two related mechanisms of senescence and proteolysis," Dr. Yadav said of the intriguing preclinical study finding. "It reduces the formation of half-dead zombie neuronal cells and also increases the degradation of (nonfunctioning) Aβ, so that amyloid protein is cleared from the brain much faster." Before you start throwing lots of extra basil in your spaghetti sauce or anything else you eat to help stave off dementia, more research is needed—including in humans. In exploring fenchol as a possible approach for treating or preventing Alzheimer's pathology, the USF Health team will seek answers to several questions. A key one is whether fenchol consumed in basil itself would be more or less bioactive (effective) than isolating and administering the compound in a pill, Dr. Yadav said. "We also want to know whether a potent dose of either basil or fenchol would be a quicker way to get the compound into the brain." Researchers find sense of purpose associated with better memory Florida State University, October 6, 2021 Add an improved memory to the list of the many benefits that accompany having a sense of purpose in life. A new study led by Florida State University researchers showed a link between an individual's sense of purpose and their ability to recall vivid details. The researchers found that while both a sense of purpose and cognitive function made memories easier to recall, only a sense of purpose bestowed the benefits of vividness and coherence. The study, which focused on memories related to the COVID-19 pandemic, was published in the journal Memory. "Personal memories serve really important functions in everyday life," said Angelina Sutin, a professor in the College of Medicine and the paper's lead author. "They help us to set goals, control emotions and build intimacy with others. We also know people with a greater sense of purpose perform better on objective memory tests, like remembering a list of words. We were interested in whether purpose was also associated with the quality of memories of important personal experiences because such qualities may be one reason why purpose is associated with better mental and physical health." Nearly 800 study participants reported on their sense of purpose and completed tasks that measured their cognitive processing speed in January and February 2020, before the ongoing coronavirus pandemic took hold in the U.S. Researchers then measured participants' ability to retrieve and describe personal memories about the pandemic in July 2020, several months into the public health crisis. Participants with a stronger sense of purpose in life reported that their memories were more accessible, coherent and vivid than participants with less purpose. Those with a higher sense of purpose also reported many sensory details, spoke about their memories more from a first-person perspective and reported more positive feeling and less negative feeling when asked to retrieve a memory. The researchers also found that depressive symptoms had little effect on the ability to recall vivid details in memories, suggesting that the connection between life purpose and memory recall is not due to the fewer depressive symptoms among individuals higher in purpose. Purpose in life has been consistently associated with better episodic memory, such as the number of words retrieved correctly on a memory task. This latest research expands on those connections to memory by showing a correlation between purpose and the richness of personal memory. "We chose to measure the ability to recall memories associated with the COVID-19 pandemic because the pandemic is an event that touched everyone, but there has been a wide range of experiences and reactions to it that should be apparent in memories," said co-author Martina Luchetti, an assistant professor in the College of Medicine. Along with the association with better memory, previous research has found other numerous benefits connected with having a sense of purpose, from a lower risk of death to better physical and mental health. "Memories help people to sustain their well-being, social connections and cognitive health," said co-author Antonio Terracciano, a professor in the College of Medicine. "This research gives us more insight into the connections between a sense of purpose and the richness of personal memories. The vividness of those memories and how they fit into a coherent narrative may be one pathway through which purpose leads to these better outcomes. Vitamin D protects against severe asthma attacks Queen Mary University of London, October 3, 2021 Taking oral vitamin D supplements in addition to standard asthma medication could halve the risk of asthma attacks requiring hospital attendance, according to research led by Queen Mary University of London (QMUL). Asthma affects more than 300 million people worldwide and is estimated to cause almost 400,000 deaths annually. Asthma deaths arise primarily during episodes of acute worsening of symptoms, known as attacks or 'exacerbations', which are commonly triggered by viral upper respiratory infections. Vitamin D is thought to protect against such attacks by boosting immune responses to respiratory viruses and dampening down harmful airway inflammation. The new study, funded by the National Institute for Health Research, and published in The Lancet Respiratory Medicine, collated and analysed the individual data from 955 participants in seven randomised controlled trials, which tested the use of vitamin D supplements. Overall, the researchers found that vitamin D supplementation resulted in: a 30 per cent reduction in the rate of asthma attacks requiring treatment with steroid tablets or injections - from 0.43 events per person per year to 0.30. a 50 per cent reduction in the risk of experiencing at least one asthma attack requiring Accident and Emergency Department attendance and/or hospitalisation - from 6 per cent of people experiencing such an event to 3 per cent. Vitamin D supplementation was found to be safe at the doses administered. No instances of excessively high calcium levels or renal stones were seen, and serious adverse events were evenly distributed between participants taking vitamin D and those on placebo. Lead researcher Professor Adrian Martineau said: "These results add to the ever growing body of evidence that vitamin D can support immune function as well as bone health. On average, three people in the UK die from asthma attacks every day. Vitamin D is safe to take and relatively inexpensive so supplementation represents a potentially cost-effective strategy to reduce this problem." The team's use of individual participant data also allowed them to query the extent to which different groups respond to vitamin D supplementation, in more detail than previous studies. In particular, vitamin D supplementation was found to have a strong and statistically-significant protective effect in participants who had low vitamin D levels to start with. These participants saw a 55 per cent reduction in the rate of asthma exacerbations requiring treatment with steroid tablets or injections - from 0.42 events per person per year to 0.19. However, due to relatively small numbers of patients within sub-groups, the researchers caution that they did not find definitive evidence to show that effects of vitamin D supplementation differ according to baseline vitamin D status. Professor Hywel Williams, Director of the NIHR Health Technology Assessment Programme, said: "The results of this NIHR-funded study brings together evidence from several other studies from over the world and is an important contribution to reducing uncertainties on whether Vitamin D is helpful for asthma - a common condition that impacts on many thousands of people worldwide." Dr David Jolliffe from QMUL, first author on the paper, added: "Our results are largely based on data from adults with mild to moderate asthma: children and adults with severe asthma were relatively under-represented in the dataset, so our findings cannot necessarily be generalised to these patient groups at this stage. Further clinical trials are on-going internationally, and we hope to include data from them in a future analysis to determine whether the promise of today's results is confirmed in an even larger and more diverse group of patients." Study Shows Lifestyle Choices Have Significant Impact on Multiple Chronic Conditions, Significant Implications For Reducing Costs Yale University, October 05, 2021 In a study published in the Journal of Preventive Medicine, Adams and colleagues showed a linear association between a number of modifiable risk factors and multiple chronic conditions, making those modifications a key to health care cost savings and to preventing a wide range of conditions. The data analyzed for the study, https://authors.elsevier.com/a/1VpFeKt2pmc9H, were from the publicly available 2013 Behavioral Risk Factor Surveillance System and included 483,865 non-institutionalized US adults ages 18 years old or older. Chronic conditions included asthma, arthritis, heart disease, stroke, chronic obstructive pulmonary disease (COPD), cognitive impairment, cancer other than skin, and kidney disease. Risk factors included obesity, current smoking, sedentary lifestyle, inadequate fruit and vegetable consumption and sleeping other than seven to eight hours, while depression, hypertension, high cholesterol, and diabetes were considered in each category. Previous research by Thorpe and colleagues had estimated that the care of adults with four or more chronic conditions (17.1% of all adults in the study) is responsible for 77.6% of all health care costs in the U.S. today. The potential savings by reducing just two risk factors (diabetes and hypertension) and their related comorbidity was estimated previously by Ormond and colleagues at $9 billion annually over one to two years and closer to $25 billion a year after 5 years or more, factoring in possible complications. True Health Initiative founder, at Yale University Director and study co-author David L. Katz, MD, MPH, FACLM, pointed out that in addition to costs, another implication of the study results is an individual's access to healthcare if they have one or more of the chronic conditions. "Although insurers decide what qualifies as a pre-existing condition, all the chronic conditions used in this study except cognitive impairment are commonly included," he said. "Individuals with a pre-existing condition could be denied coverage or face higher premiums. While having a pre-existing condition might not affect coverage for adults eligible for Medicare, over half of all adults with multiple chronic conditions are ages 18 to 64 years." American College of Lifestyle Medicine President George Guthrie, MD, MPH, FACLM, said the study confirms the necessity for addressing the root cause of chronic conditions. "The evidence shows that the risks for chronic disease are rooted in lifestyle choices," he said. "More than ever, it is important to emphasize lifestyle medicine as the first treatment option for preventing, treating, and in some cases, reversing the cause of chronic conditions. If we can help people with chronic conditions, we can add years to their life and life to their years, as well as lower the ever-increasing costs of healthcare for everyone." Physical athletes' visual skills prove sharper than action video game players University of Waterloo (Canada), October 7, 2021 Athletes still have the edge over action video gamers when it comes to dynamic visual skills, a new study from the University of Waterloo shows. For an athlete, having strong visual skills can be the difference between delivering a peak performance and achieving average results. "Athletes involved in sports with a high-level of movement—like soccer, football, or baseball—often score higher on dynamic visual acuity tests than non-athletes," said Dr. Kristine Dalton of Waterloo's School of Optometry & Vision Science. "Our research team wanted to investigate if action video gamers—who, like e-sport athletes, are regularly immersed in a dynamic, fast-paced 2D video environment for large periods of time—would also show superior levels of dynamic visual acuity on par with athletes competing in physical sport." While visual acuity (clarity or sharpness of vision) is most often measured under static conditions during annual check-ups with an optometrist, research shows that testing dynamic visual acuity is a more effective measure of a person's ability to see moving objects clearly—a baseline skill necessary for success in physical and e-sports alike. Using a dynamic visual acuity skills-test designed and validated at the University of Waterloo, researchers discovered that while physical athletes score highly on dynamic visual acuity tests as expected, action video game players tested closer to non-athletes. "Ultimately, athletes showed a stronger ability to identify smaller moving targets, which suggests visual processing differences exist between them and our video game players," said Alan Yee, a Ph.D. candidate in vision science. All participants were matched based on their level of static visual acuity and refractive error, distinguishing dynamic visual acuity as the varying factor on their test performance. These findings are also important for sports vision training centers that have been exploring the idea of developing video game-based training programs to help athletes elevate their performance. "Our findings show there is still a benefit to training in a 3D environment," said Dalton. "For athletes looking to develop stronger visual skills, the broader visual field and depth perception that come with physical training may be crucial to improving their dynamic visual acuity—and ultimately, their sport performance." The study, Athletes demonstrate superior visual dynamic visual acuity, authored by Waterloo's School of Optometry & Vision Science's Dalton, Yee, Dr. Elizabeth Irving and Dr. Ben Thompson, was recently published in the journal Optometry and Vision Science. Probiotic Akkermansia muciniphila and environmental enrichment reverse cognitive impairment associated with high-fat high-cholesterol consumption University of Oviedo (Spain), September 8, 2021 Nonalcoholic steatohepatitis (NASH) is one of the most prevalent diseases globally. A high-fat, high-cholesterol (HFHC) diet leads to an early NASH model. It has been suggested that gut microbiota mediates the effects of diet through the microbiota–gut–brain axis, modifying the host's brain metabolism and disrupting cognition. Here, we target NASH-induced cognitive damage by testing the impact of environmental enrichment (EE) and the administration of either Lacticaseibacillus rhamnosus GG (LGG) or Akkermansia muciniphila CIP107961 (AKK). EE and AKK, but not LGG, reverse the HFHC-induced cognitive dysfunction, including impaired spatial working memory and novel object recognition; however, whereas AKK restores brain metabolism, EE results in an overall decrease. Moreover, AKK and LGG did not induce major rearrangements in the intestinal microbiota, with only slight changes in bacterial composition and diversity, whereas EE led to an increase in Firmicutes and Verrucomicrobia members. Our findings illustrate the interplay between gut microbiota, the host's brain energy metabolism, and cognition. In addition, the findings suggest intervention strategies, such as the administration of AKK, for the management of the cognitive dysfunction related to NASH. In this study, we described cognitive, brain metabolism, and microbiota alterations associated with high-fat and high-cholesterol consumption. In addition, we clearly showed that environmental enrichment and A. muciniphila CIP107961 restore cognitive dysfunction. Furthermore, we revealed that cognitive improvement is associated with differential effects of environmental enrichment and this strain of A. muciniphila on brain metabolism and gut microbiota. Finally, we discovered that restored cognitive function was associated with the administration of A. muciniphila CIP107961, but not L. rhamnosus GG, which may be clinically relevant when selecting probiotics for treating HFHC-derived pathologies. In conclusion, the microbiota and cognition are intimately connected through the gut–brain axis, and in HFHC pathologies they can be influenced by environmental enrichment and A. muciniphila CIP107961 administration. Cognitive improvement was accompanied by changes in brain metabolic activity and gut microbial composition analysis, pointing to specific microbiota targets for intervention in diet-induced pathologies. However, some mechanisms other than major changes in microbiota composition and the combined effect of environmental enrichment and A. muciniphila administration, which we identified in this study, may also be biologically relevant and will need to be investigated in future studies due to their relative contributions to the selection of effective treatments for patients.
Produced by: Catherine Charlwood (@DrCharlwood) and Laura Ludtke (@lady_electric) Music composed and performed by Gareth Jones. About the episode: This sixth episode of the third series of LitSciPod features an interview with Dr Heather Love, Assistant Professor of English Literature at the University of Waterloo (Canada). Heather discusses her work on cybernetics in the works of Ezra Pound, John Dos Passos, and Virginia Woolf, as well as modernism and diagnosis. She introduces us to her new project on obstetrics and explores her unique relationship with the IEEE (Institute of Electrical and Electronics Engineers). Together, we consider the importance of the concept of the cluster to her research. At the end of the episode, you can hear Heather read an excerpt from Gertrude Stein's Everybody's Autobiography (1937). Episode resources (in order of appearance): • Gabriel Roberts, “ The Humanities in Modern Britain: Challenges and Opportunities”, Higher Education Policy Institute (2021) • Lord Browne, “Securing a sustainable future for higher education: an independent review of higher education funding and student finance” (2010) • Royal Society, “Jobs are changing, so should education” (2019) • Heather Love, “The Cluster as Interpretive Gesture” in “Traces”, Open Thresholds (2017): http://openthresholds.org/2/clusterasinterpretivegesture. • Love, “Newsreels, Novels, and Cybernetics: Reading the Random Patterns of John Dos Passos's U.S.A.”, Journal of Modern Literature • Janet Galligani Casey, Dos Passos and the Ideology of the Feminine (1998) • Walter Pater, The Renaissance • William James, The Principles of Psychology • Ross Ashby, “The Black Box”, An Introduction to Cybernetics (1956). • Sylvan Thompkins, Affect Imagery Consciousness: The Positive Affects (1962) • Virginia Woolf, The Waves (1931) •Dorothy Richardson, Pilgrimage (1915–38) • Paul Jaussen, Writing in Real Time: Emergent Poetics from Whitman to the Digital (2017) • John Dos Passos, USA Trilogy (1930–6); Manhattan Transfer (1925) • Love, “Cybernetic Modernism and the Feedback Loop: Ezra Pound's Poetics of Transmission”, Modernism/modernity (2016) • Joy Division, “Transmission”, Novelty (1979) •Ezra Pound, Cantos LII–LXXI (1940) • Woolf, “Character in Fiction” The Criterion (1924) • Ford Madox Ford, “On Impressionism,” Poetry and Drama (1913) • Rudolf Arnheim, Rundfunk als hörkunst (1933), translated as Radio as Sound (1936) • University of Waterloo, Co-op Program (https://uwaterloo.ca/future-students/co-op); Master of Arts in Experimental Digital Media (https://uwaterloo.ca/english/xdm) • Siegfried Zielinski, [. . . After the Media]: News from the Slow-Fading Twentieth Century (2013) • Love & Lisa Mendelman, Modernism and Diagnosis in Modernism/modernity Print Plus 6.2 (2021): https://doi.org/10.26597/mod.0198 • Kevin Jackson, Constellation of Genius: 1922: Modernism Year One (2012) • Paul Stephens, The Poetics of Information Overload: From Gertrude Stein to Conceptual Writing (2015) Stephens, “Stars in My Pocket Like Bits of Data: The poetics of information overload”, Guernica (15 July 2015) • Robertson Collection, Museum of Healthcare at Kingston. See https://www.atlasobscura.com/articles/objects-of-intrigue-museum-of-health-care-moulages
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Clinical Significance of Micronutrient Supplementation in Critically Ill COVID-19 Patients with Severe ARDS University Hospital Wuerzburg (Germany), June 12, 2021 Abstract The interplay between inflammation and oxidative stress is a vicious circle, potentially resulting in organ damage. Essential micronutrients such as selenium (Se) and zinc (Zn) support anti-oxidative defense systems and are commonly depleted in severe disease. This single-center retrospective study investigated micronutrient levels under Se and Zn supplementation in critically ill patients with COVID-19 induced acute respiratory distress syndrome (ARDS) and explored potential relationships with immunological and clinical parameters. According to intensive care unit (ICU) standard operating procedures, patients received 1.0 mg of intravenous Se daily on top of artificial nutrition, which contained various amounts of Se and Zn. Micronutrients, inflammatory cytokines, lymphocyte subsets and clinical data were extracted from the patient data management system on admission and after 10 to 14 days of treatment. Forty-six patients were screened for eligibility and 22 patients were included in the study. Twenty-one patients (95%) suffered from severe ARDS and 14 patients (64%) survived to ICU discharge. On admission, the majority of patients had low Se status biomarkers and Zn levels, along with elevated inflammatory parameters. Se supplementation significantly elevated Se (p = 0.027) and selenoprotein P levels (SELENOP; p = 0.016) to normal range. Accordingly, glutathione peroxidase 3 (GPx3) activity increased over time (p = 0.021). Se biomarkers, most notably SELENOP, were inversely correlated with CRP (rs = −0.495), PCT (rs = −0.413), IL-6 (rs = −0.429), IL-1β (rs = −0.440) and IL-10 (rs = −0.461). Positive associations were found for CD8+ T cells (rs = 0.636), NK cells (rs = 0.772), total IgG (rs = 0.493) and PaO2/FiO2ratios (rs = 0.504). In addition, survivors tended to have higher Se levels after 10 to 14 days compared to non-survivors (p = 0.075). Sufficient Se and Zn levels may potentially be of clinical significance for an adequate immune response in critically ill patients with severe COVID-19 ARDS. Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms Louisiana State University, June 20, 2021 Insomnia is common in the elderly and is associated with chronic disease, but use of hypnotics increases the incidence of falls. Montmorency tart cherry juice has improved insomnia by self-report questionnaire. Study Question: Is insomnia confirmed by polysomnography and is tryptophan availability a potential mechanism for treating insomnia? Study Design: A placebo-controlled balanced crossover study with subjects older than 50 years and insomnia were randomized to placebo (2 weeks) or cherry juice (2 weeks) (240 mL 2 times/d) separated by a 2-week washout. Measures and Outcomes: Sleep was evaluated by polysomnography and 5 validated questionnaires. Serum indoleamine 2,3-dioxygenase (IDO), the kynurenine-to-tryptophan ratio, and prostaglandin E2 were measured. In vitro, Caco-2 cells were stimulated with interferon-gamma, and the ability of cherry juice procyanidin to inhibit IDO which degrades tryptophan and stimulates inflammation was measured. The content of procyanidin B-2 and other major anthocyanins in cherry juice were determined. Results: Eleven subjects were randomized; 3 with sleep apnea were excluded and referred. The 8 completers with insomnia increased sleep time by 84 minutes on polysomnography (P = 0.0182) and sleep efficiency increased on the Pittsburgh Sleep Quality Index (P = 0.03). Other questionnaires showed no significant differences. The serum kynurenine-to-tryptophan ratio decreased, as did the level of prostaglandin E2 (both P < 0.05). In vitro, cherry juice procyanidin B-2 dose-dependently inhibited IDO. Conclusions: Cherry juice increased sleep time and sleep efficiency. Cherry juice procyanidin B-2 inhibited IDO, increased tryptophan availability, reduced inflammation, and may be partially responsible for improvement in insomnia. Many with migraines have vitamin deficiencies, says study Cincinnati Children's Hospital, June 10, 2021 A high percentage of children, teens and young adults with migraines appear to have mild deficiencies in vitamin D, riboflavin and coenzyme Q10—a vitamin-like substance found in every cell of the body that is used to produce energy for cell growth and maintenance. These deficiencies may be involved in patients who experience migraines, but that is unclear based on existing studies. "Further studies are needed to elucidate whether vitamin supplementation is effective in migraine patients in general, and whether patients with mild deficiency are more likely to benefit from supplementation," says Suzanne Hagler, MD, a Headache Medicine fellow in the division of Neurology at Cincinnati Children's Hospital Medical Center and lead author of the study. Dr. Hagler and colleagues at Cincinnati Children's conducted the study among patients at the Cincinnati Children's Headache Center. She will present her findings at 9:55 am Pacific time Friday, June 10, 2016 at the 58th Annual Scientific Meeting of the American Headache Society in San Diego. Dr. Hagler's study drew from a database that included patients with migraines who, according to Headache Center practice, had baseline blood levels checked for vitamin D, riboflavin, coenzyme Q10 and folate, all of which were implicated in migraines, to some degree, by previous and sometimes conflicting studies. Many were put on preventive migraine medications and received vitamin supplementation, if levels were low. Because few received vitamins alone, the researchers were unable to determine vitamin effectiveness in preventing migraines. She found that girls and young woman were more likely than boys and young men to have coenzyme Q10 deficiencies at baseline. Boys and young men were more likely to have vitamin D deficiency. It was unclear whether there were folate deficiencies. Patients with chronic migraines were more likely to have coenzyme Q10 and riboflavin deficiencies than those with episodic migraines. Previous studies have indicated that certain vitamins and vitamin deficiencies may be important in the migraine process. Studies using vitamins to prevent migraines, however, have had conflicting success. Research suggests mask-wearing can increase struggles with social anxiety University of Waterloo (Canada), June 21, 2021 People who struggle with social anxiety might experience increased distress related to mask-wearing during and even after the COVID-19 pandemic. A paper authored by researchers from the University of Waterloo's Department of Psychology and Centre for Mental Health Research and Treatment also has implications for those who haven't necessarily suffered from social anxiety in the past. "The adverse effects of the COVID-19 pandemic on mental health outcomes, including anxiety and depression, have been well-documented," said David Moscovitch, professor of clinical psychology and co-author of the paper. "However, little is known about effects of increased mask-wearing on social interactions, social anxiety, or overall mental health. "It is also possible that many people who didn't struggle with social anxiety before the pandemic may find themselves feeling more anxious than usual as we emerge out of the pandemic and into a more uncertain future -- especially within social situations where our social skills are rusty and the new rules for social engagement are yet to be written." Social anxiety is characterized by negative self-perception and fear that one's appearance or behaviour will fail to conform with social expectations and norms. Social anxiety disorder is an extreme manifestation that affects up to 13 per cent of the population. The researchers reviewed existing literature addressing three factors that they hypothesized might contribute to social anxiety associated with mask-wearing: hypersensitivity to social norms, bias in the detection of social and emotional facial cues, and propensity for self-concealment as a form of safety behaviour. "We found that mask-wearing by people with social anxiety is likely to be influenced by their perception of social norms and expectations, which may or may not be consistent with public-health guidelines and can vary widely by region and context," said Sidney Saint, an undergraduate psychology student at Waterloo and lead author of the paper. The paper also highlights that people with social anxiety have difficulty detecting ambiguous social cues and are likely to interpret them negatively. These individuals also tend to worry about sounding incomprehensible or awkward. "We believe that both issues are likely to be magnified during interactions with masks," Saint said. Another highlighted impact is that masks can function as a type of self-concealment strategy that enables people with social anxiety to hide their self-perceived flaws. Therefore, the desire for self-concealment may motivate their use of masks over and above their desire to protect themselves from contagion. "Due to their self-concealing function, masks may be difficult for some people to discard even when mask-wearing is no longer required by public health mandates," Saint said. In addition to contributing insights to guide clinicians toward effective assessment and treatment, the paper shows that people with social anxiety may be particularly vulnerable to periods of norm transitions where expectations for mask-wearing are in flux or become a matter of personal choice. Going with your gut can result in better decision-making than using detailed data methods, study shows City University London, June 21, 2021 Managers who use their gut instinct together with simple decision-making strategies may make equally good, but faster, decisions as those who use data to reach an outcome, a new study has found. The report, co-authored by academics at the Business School (formerly Cass), King's Business School, and the University of Malta, finds that the reliance on data analysis in decision-making might be counterproductive as this reduces decision-making speed without ensuring more accuracy. The research, based on information from 122 advertising, digital, publishing, and software companies, finds that using data to inform decision making under high uncertainty is often not optimal. This may explain why 12 different publishers initially rejected the opportunity to publish "Harry Potter and the Philosopher's Stone' – because it had no data to inform its potential. A recent survey revealed that 92 percent of Fortune 1000 companies were reporting increased investment in data initiatives, although it appears this may not always be necessary. The authors asked managers how they made decisions on their most recent innovation project, including the extent to which they used data, instinct, and other simple heuristics (mental strategies). The findings outlined that among those decision-making methods were: Majority—choosing what the most people wanted Tallying—picking the choice with the greatest quantity of positive points Experience—selecting the option that the most experienced individual on the team wanted. Managers were asked whether they think they made the right decision and how fast they were in reaching that decision. Results showed that managers relied on their own instinct as much as data, using 'tallying' more than any other metric. Dr. Oguz A. Acar, Reader in Marketing at the Business School and co-author of the report, said: "This research shows that data-driven decision-making is not the panacea in all situations and may not result in increased accuracy when facing uncertainty. "Under extreme uncertainty, managers, particularly those with more experience, should trust the expertise and instincts that have propelled them to such a position. The nous developed over years as a leader can be a more effective than an analytical tool which, in situations of extreme uncertainty, could act as a hindrance rather than a driver of success." "Choosing among alternative new product development projects: The role of heuristics" is published in Psychology and Marketing. Pretreatment by rosemary extract or cell transplantation improves memory deficits of Parkinson disease Damghan University (Iran) June 21 2021 According to news originating from Damghan, Iran, research stated, “The therapeutic effect of adipose tissue-derived stem cells (ADSCs) or RE on hippocampal neurogenesis and memory in Parkinsonian rats were investigated. Male rats were lesioned by bilateral intra-nigral injections of 6-OHDA and divided into six groups: 1. Lesion 2 and 3: RE and water groups were lesioned rats pretreated with RE or water, from 2weeks before neurotoxin injection and treated once a day for 8weeks post lesion. 4&5: Cell and alpha-MEM (alpha-minimal essential medium) received intravenous injection of BrdU-labeled ADSCs or medium, respectively from 10days post lesion until 8weeks later. 6: Sham was injected by saline instead of neurotoxin.” Our news journalists obtained a quote from the research from Damghan University, “Memory was assessed using Morris water Maze (MWM), one week before and at 1, 4 and 8weeks post 6-OHDA lesion. After the last probe, the animals were sacrificed and brain tissue obtained. Paraffin sections were stained using cresyl violet, anti-BrdU (Bromodeoxyuridine / 5-bromo-2'-deoxyuridine), anti-GFAP (Glial fibrillary acidic protein) and anti-TH antibodies. There was a significant difference of time spent in the target quadrant between groups during probe trial at 4 and 8 weeks' post-lesion. Cell and RE groups spent a significantly longer period in the target quadrant and had lower latency as compared with lesion. Treated groups have a significantly higher neuronal density in hippocampus compared to water, alpha-MEM and lesion groups. BrdU positive cells were presented in lesioned sites. The GFAP (Glial fibrillary acidic protein) positive cells were reduced in treated and sham groups compared to the water, alpha-MEM and lesion groups.” According to the news editors, the research concluded: “Oral administration of RE (Rosemary extract) or ADSCs injection could improve memory deficit in the Parkinsonian rat by neuroprotection.” Inadequate vitamin D levels associated with interstitial lung disease Johns Hopkins University, June 20 2021. An article appearing in the Journal of Nutrition documents a link between decreased vitamin D levels and a greater risk of early signs of interstitial lung disease (ILD), a group of disorders characterized by inflammation and scarring that can lead to lung damage. Although ILD can be caused by environmental and other factors, some cases have unknown causes. The investigation included 6,302 participants in the Multi-Ethnic Study of Atherosclerosis who had information available concerning their initial serum 25-hydroxyvitamin D concentrations and computed tomography (CT) imaging that included partial views of the lungs. Ten years after enrollment, 2,668 participants had full lung CT scans that were evaluated for presence of scar tissue and other abnormalities. Subjects who had deficient vitamin D levels of less than 20 ng/mL had more spots on their lungs that were suggestive of damage in comparison with subjects whose vitamin D was adequate. Among those who had full lung CT scans, deficient or intermediate (between 20-30 ng/mL) vitamin D levels were associated with a 50-60% greater risk of abnormalities suggestive of ILD. "We knew that the activated vitamin D hormone has anti-inflammatory properties and helps regulate the immune system, which goes awry in ILD," commented senior author Erin Michos, MD, MHS. “There was also evidence in the literature that vitamin D plays a role in obstructive lung diseases such as asthma and COPD, and we now found that the association exists with this scarring form of lung disease too." "Our study suggests that adequate levels of vitamin D may be important for lung health,” she concluded. “We might now consider adding vitamin D deficiency to the list of factors involved in disease processes, along with the known ILD risk factors such as environmental toxins and smoking.”
Join The New Humanity Initiative™ and Canada CFO's Inc. in partnership with the Canadian Association of Urban Financial Professionals (CAUFP) along with our cast of amazing speakers and thought leaders who will promote and amplify equity diversity and inclusion in the accounting and finance sector. Leadership and Change in Accounting & Finance is an immersive and interactive digital event with a view towards strengthening Economic Mobility for BIPOC Communities. It will feature curated conversations, engagement and experience addressing anti-Black racism, crucial challenges, meaningful change and innovative impact in creating inclusive and equitable opportunities. A dynamic and interactive experience for attendees, speakers, supporters and stakeholders of the event, where individuals can communicate their points of view. The event will feature a Dialogues on Diversity by prominent Finance Leaders as well as a Panel discussion on the issues, followed by a ‘Voices in Action' breakout segment. (5 Concurrent Sessions) Join us after the Panel Discussion for our breakout sessions where we will have community participation and conversations about taking collective action. The Voices in Action are based on the “Economic Mobility” Pillar one of the seven pillars of The New Humanity Initiative that will help shape its outcomes-based approach to achieve national change. Each session will be facilitated by Thought Leaders who are actively championing change within these areas under the Economic Mobility Pillar. Please bring your ideas and get ready to create meaningful change. Kindly select the Voices in Action (Breakout) Session that you would like to be a part of during registration. - Capital & Finance - Culture and Organizational Change - Health & Wellbeing - Investment, Enablement and Financial Services - Leadership & Inclusion Together we can strengthen actions and implement strategies to improve professional outcomes for BIPOC Professionals. Hugh Anthony Simmonds, PhD is the Co-Founder and Co-Chair, The New Humanity Initiative™. Hugh Anthony is the Co-founder and Co-Chair of The New Humanity Initiative™ a purpose-fueled national organization that is a catalyst for fundamental change to strengthen equity, access and inclusivity for racialized groups throughout Canada, and the first black member to serve as Director for the Toronto Music Festival, the oldest arts and music festival in Canada. Currently he serves as the President of Metropolitan Toronto Condominium Corporation (MTCC) 934 and is a Distinguished President of the Kiwanis Club of Toronto Caribbean. Hugh Anthony is currently Head of Strategy, Assignment & Co. a boutique lifestyle consultancy firm based in Toronto, Canada and a Teaching Faculty at Ryerson University in the Faculty of Arts and the G. Raymond Chang School of Continuing Education. Hugh Anthony, believes that “everyone is gifted, but some people never open their package”. Hugh Anthony received his Doctor of Philosophy (PhD) from the University of Waterloo (Canada) and Master of Science (MSc), Postgraduate Diploma (PGDE) and Bachelor of Science (BSc) from the University of the West Indies (Jamaica). In addition, he as taken numerous executive education courses at Harvard University (USA), Ryerson University (Canada) and University of New Orleans(USA). With 20+ years of progressive multi-sector engagements, holding appointments as Executive Director for a nonprofit organization, International President for Kiwanis International Service Leadership organization, Hugh Anthony brings conceptual and strategic thinking with significant experience and expertise in higher education management, non-profit leadership, board governance, fundraising and capacity building. He has played a pivotal role in leading and strengthening individuals and organizations, through visioning, strategic planning, learning and development, marketing and communications, networking, collaborations and partnerships, advocacy and leading people-centered programming, workshops and initiatives. Hugh Anthony is an avid volunteer and believes that “service is the rent we pay for living” and have traveled throughout North America, South America, Europe, Asia and the Caribbean. He brings mastery in public speaking and storytelling with his award-winning presentation skills to help individuals uncover their passion, unfold their purpose and share the power of their stories. His scholarship, research and consultancies span cultural organizations, leisure, tourism, hospitality geography, international politics, governance and policy; and professional services from the lens of culture, equity, intersectionality and lifestyle. He brings a wealth of teaching and learning experience having held appointments at the University of Technology (Jamaica) College of Business and Management; the University of Waterloo (Canada) Department of Recreation and Leisure Studies, Ryerson University (Canada) Department of Geography and Environmental Studies and G. Raymond Chang School of Continuing Studies. Hugh Anthony presented his research at several international conferences, his groundbreaking research on film festivals, field-configuring events and cultural organizations and his lifestyle writing and publications have been included on major digital media platforms and he is currently finishing a book publication project – The Ultimate Guide to Public Speaking: Seven Steps to Professional Mastery (forthcoming Spring 2022). Mr. Anthony was live on our show tonight talking about the The New Humanity Initiative – Leadership And Change In Accounting & Finance Interactive Digital Event which is happening on November 12, 2020. During the conversation, Mr. Anthony talked about: – Some of his background including at nine years old realizing that his life would be one of service – the story behind that The New Humanity Initiative™, some of the keys of success so far, memories of the first event and highlights from some of the past events, – His thoughts on the state of equity and diversity in Canada at this time – What to expect during the November 12, 2020 event You can find more about The New Humanity Initiative – Leadership And Change In Accounting & Finance Interactive Digital Event happening on November 12, 2020 by clicking here You can find out more about The New Humanity Initiative™ via: Website Email You can find out more about Mr. Anthony via: Linkedin Instagram Twitter Visit The Dr. Vibe Show™ at www.thedrvibeshow.com Please feel free to email us at dr.vibe@thedrvibeshow.com Please feel free to “Like” the “The Dr. Vibe Show” Facebook fan page here God bless, peace, be well and keep the faith, Dr. Vibe dr.vibe@thedrvibeshow.com 2018 Innovation Award Winner – Canadian Ethnic Media Association The Dr. Vibe Show™ At “The Good Men Project” One of the first Brand Ambassador's – Cuisine Noir Magazine Dr. Vibe – Producer And Co-host of Black Men Talking On WJMS Radio Dr. Vibe on HuffPost Live – August 2, 2013 2013 Black Weblog Awards Finalist (Best Podcast) 2012 Black Weblog Awards Winner (Best International Blog) 2012 Black Weblog Awards Finalist (Best Podcast) 2011 Black Weblog Awards Finalist (Best International Blog and Best Podcast Series) Black Blog Of The Day – Black Bloggers Network – June 23, 2011 Twitter Twitter hashtag: #DrVibe The Dr. Vibe Show™ – iTunes The Dr. Vibe Show™ – Spotify Dr. Vibe Media – You Tube The Dr. Vibe Show™ – Stitcher Radio The Dr. Vibe Show™ – TuneIn Radio The Dr. Vibe Show™ – Google Play Music The Dr. Vibe Show™ – iHeartRadio The Dr. Vibe Show™ at Anchor Linkedin – The Dr. Vibe Show™ Instagram The Dr. Vibe Show Facebook Fan Page
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Gord captures your attention right from the start. Being a suicide survivor he created his mission to meaningfully connect with 10 million men globally in the next 24 months with a message of HOPE that there ARE ways of dealing with stress, anxiety and depression without 'outing yourself'. During this episode we learn:The exact moment that changed Gord’s pathWhy he got a tattoo, what it is, and the impact it has on others when they see itWhat taking a year to get healthy looked like for GordGord shares the signs, from the first signs, small ones straight to big major signs and how these signs built on each otherWhy having “a BIG why that makes you cry” is so critical!What are the 5 sentences to ask yourself Gord is so inspiring; he opens up and shares all parts of him in this episode.More about Gord; Gordon is a Multi-Award Winning, International Best Selling Author, Founder of JEWIL International, is an Elite Speaker, runs his own seminars for men ‘BOXED INSIDE OUT’, and is a Co-Owner, Co-Producer, Co-MoHost & Co-Emcee of momondays Waterloo, as well, he does corporate sales and marketing for the ‘Think and Grow Rich Institute’, sits on several boards, is active in his church and volunteers with several charities. He still finds time to help his wife of 27 years to raise their three active growing young sons!After being introduced to the world of sales through the automotive industry, Gordon D. Melville went on to work with several of the biggest names in the personal development world including Zig Zigler and Grant Cardone in his early 20’s.Once he broke records in sales and lead dozens of dealerships to their success through his inspiring character, skilful persuasion & learned business acumen; Gordon battled and continues to win the war of depression from severe burnout due to overworking himself and has completely reprioritized everything in his life.Mastering sales & personal development for over 25+ years, Gordon now has read well over 1,500 books and spent a small fortune on intentional personal growth for high level mentors, and on seminars in those fields. He is certified in multiple disciplines including ‘Strategic Intervention’ through Tony Robbins and founded JEWIL INTERNATIONAL; which is a successful international coaching practice that guides people to creating and living their designed, extraordinary life.Gordon fuels his definite major purpose with his mission to have meaningful, positively impactful connections with ten million men globally within the next 24 months; with the message that there IS hope for dealing with mental illness, depression, stress & anxiety. He provides tools and strategies; and in more severe cases, resources, towards men taking back their power of being successful to manage their own mind with a positive mental attitude; without resorting to the vices that we as men typically do, which do not solve the challenge and more often than not make things worse.Gordon resides in Waterloo Canada with his wife and their three active boys. He has written several books, has been featured on many podcasts, as well as in several blogs and articles, and is a driven serial entrepreneur.For more information about local programs with JEWIL INTERNATIONAL, BOXED INSIDE OUT programs & workshops in your area, to bring ‘Think and Grow Rich’ technologies into your business, or to make direct contact with Gordon, please reach out at: jewil.coaching@gmail.com or find him on Facebook, LinkedIn or TwitterWhere to reach Gord:Gordon D Melville on facebookgordmelville on LinkedInjewil.coaching@gmail.com
Is apologizing a sorry excuse for kindness? Four Times You Shouldn’t Apologize (Including When It’s Your Fault) https://www.fastcompany.com/40444338/four-times-you-shouldnt-apologize-including-when-its-your-fault Why women apologize more than men: gender differences in thresholds for perceiving offensive behavior. https://www.nytimes.com/2015/06/23/opinion/when-an-apology-is-anything-but.html When Saying Sorry May Not Help: The Impact of Apologies on Social Rejections https://www.frontiersin.org/articles/10.3389/fpsyg.2017.01375/full Why women apologize more than men: gender differences in thresholds for perceiving offensive behavior. https://www.ncbi.nlm.nih.gov/pubmed/?term=University+of+Waterloo+Canada+apologize+women Just Not Sorry - The G-Mail Plug-ing https://chrome.google.com/webstore/detail/just-not-sorry-the-gmail/fmegmibednnlgojepmidhlhpjbppmlci
The Building State Capability (BSC) program at CID uses the Problem Driven Iterative Adaptation (PDIA) approach to help organizations develop the capability to solve complex problems and to implement public policies. PDIA is a process of facilitated emergence, which focuses on problems (not solutions) and follows a step by step process (not a rigid plan) that allows for flexible learning and adaptation. Today on CID’s Speaker Series podcast, Anna Mysliewic, student at the Harvard Kennedy School, interviews Salimah, who discusses the challenges and experiences BSC has faced when implementing PDIA in the field. Salimah draws on examples from BSC’s work in Albania and Sri Lanka, as well as the recent launch of the PDIAToolkit, a Do-it-Yourself kit for teams to use when solving complex problems. To learn more about PDIA: bsc.cid.harvard.edu Download the PDIAToolkit (in English and Spanish): bsc.cid.harvard.edu/PDIAtoolkit Interview recorded on March 1, 2019. About Salimah Samji: Salimah Samji is the Director of Building State Capability (BSC). She has more than 15 years of experience working in international development on the delivery of public services, transparency and accountability, strategic planning, monitoring, evaluation and learning. She joined CID in 2012 to help create the BSC program. Today, she is responsible for providing vision, strategic leadership, oversight and managing projects and research initiatives. Salimah also leads BSC’s work on digital learning. Before joining CID, she was an independent consultant working for the World Bank on issues of governance, and the Hewlett Foundation on strategic planning for one of their grantees. She has worked as a senior program manager at Google.org, leading a transparency and accountability initiative focused on empowering citizens and decision-makers, by making information on service delivery outcomes publicly available. Salimah has also worked at the World Bank as a social/rural development and monitoring and evaluation specialist in South Asia. She has a Bachelor of Mathematics from the University of Waterloo (Canada) and a Masters in Public Administration in International Development (MPA/ID) from the Harvard Kennedy School. She is a qualified Casualty Actuary who changed careers after working for 18 months in Afghan refugee camps with a Canadian NGO (FOCUS Humanitarian Assistance) based in Pakistan. Salimah has worked and lived in Kenya, India, Pakistan, Tajikistan, Canada and the USA.
Charles Eagan and Eric Cornelius: BlackBerry and Cylance Just Makes Sense Is a Terminator T-800 an endpoint? Is Voltron an endpoint? Could we have prevented a lot of damage to the Earth if Tony Stark had just installed a BlackBerry Cylance endpoint protection solution on the Iron Legion? In this week’s episode of InSecurity, Matt Stephenson chats with BlackBerry CTO Charles Eagan and BlackBerry Cylance CPO Eric Cornelius... two people charged with leading the charge to combine BlackBerry and Cylance into a security solution that will protect every Thing under the sun. Take a walk with them as Matt finds out what the future holds now that BlackBerry and Cylance have come together. If you are in San Francisco for RSA, make sure to come say hello to Charles, Eric, Matt and a lot of other interesting security folks Tuesday night at the Digital Shadows Security Leaders Party, Tuesday, March 5that 6.00 pm. Cylance will be at Booth #6145 in the North Hall. Swing by to see demos of Cylance’s Artificial Intelligence (AI) Platform which provides advanced endpoint protection and endpoint detection and response capabilities. Join us to see for yourself how the Cylance AI Platform delivers business value and outcomes you had been told were impossible. You can also snag some of our giveaways while you’re there, so come on by. About Charles Eagan Charles Eagan is the Chief Technology Officer for BlackBerry. In this role, Charles oversees the standardization and integration of all company products and is responsible for the advancement of new technologies and partnerships, with an emphasis on defining BlackBerry’s Enterprise of Things platform as well as driving innovation within emerging markets. Charles was previously the Global Head of Electronics at Dyson Ltd (U.K.), focused on IoT device deployment. Prior to that he served as BlackBerry’s Global Head of Device Software, and spearheaded development of the BlackBerry 10 operating system and the transition to secure Android. Charles was formerly Vice President of Engineering for QNX Software, where he concentrated on the automotive and embedded markets. He also worked at Cisco and directed development of the seminal CRS-1 carrier routing system. Charles is a noted speaker, thought leader and IoT expert who has been at the forefront of new frontiers in digital connectivity for over three decades. He graduated with honors from the University of Waterloo (Canada) with a bachelor’s degree in applied mathematics and electrical engineering minor. About Eric Cornelius Eric Cornelius is the Chief Product Officer at Blackberry Cylance. In this role, Eric drives product and innovation. Previously Eric served as VP of Innovation, Director of Critical Infrastructure/ICS and Technical Director of Incident Response/Critical Infrastructure at Cylance. Eric brings this wealth of knowledge and long history as a security practitioner, consultant, trusted advisor and product builder to his work in elevating our product development initiatives, and to leading our product management and corporate development teams. About Matt Stephenson Insecurity Podcast host Matt Stephenson (@packmatt73) leads the Security Technology team at Cylance, which puts him in front of crowds, cameras, and microphones all over the world. He is the regular host of the InSecurity podcast and host of CylanceTV Twenty years of work with the world’s largest security, storage, and recovery companies has introduced Stephenson to some of the most fascinating people in the industry. He wants to get those stories told so that others can learn from what has come Every week on the InSecurity Podcast, Matt interviews leading authorities in the security industry to gain an expert perspective on topics including risk management, security control friction, compliance issues, and building a culture of security. Each episode provides relevant insights for security practitioners and business leaders working to improve their organization’s security posture and bottom line. Can’t get enough of Insecurity? You can find us wherever you get your podcasts including Spotify, Stitcher, SoundCloud, I Heart Radio as well as ThreatVector InSecurity Podcasts: https://threatvector.cylance.com/en_us/category/podcasts.html iTunes/Apple Podcasts link: https://itunes.apple.com/us/podcast/insecurity/id1260714697?mt=2 GooglePlay Music link: https://play.google.com/music/listen#/ps/Ipudd6ommmgdsboen7rjd2lvste Make sure you Subscribe, Rate and Review!
Connect with Amir on LinkedIn: https://www.linkedin.com/in/amir-azarbad-14a6142/ Timestamps 01:25 - Amir’s career startup after graduating from the University of Waterloo (Canada) 03:10 - Creating your own job oppportunities and dealing with initial challenges in your career. 08:40 - Shifting to consulting and working with Deloitte as an Analyst 10:25 - Initial consulting bootcamp and adjusting to the consulting lifestyle 12:25 - Mentorship, networking, and controlling your own career in consulting 14:30 - Choosing to move to a small consulting startup (Invoyent) 17:20 - Decision making and advice around work transitions and career moves 22:50 - Differences between a career in industry vs. one in consulting 30:50 - Stepping away from industry and starting a consulting firm 35:00 - Advice on finding mentors to help navigate your career and industry 36:55 - Disrupting the consulting industry and what Inspirant Group is all about 43:09 - The Inspirant Group leadership team, culture, and more about the company 46:45 - Final advice from Amir on your career Episode Notes Inspiring Group, Inc: https://inspirantgrp.com University of Waterloo: https://uwaterloo.ca/ Follow Career Startups Facebook: www.facebook.com/careerstartups/ LinkedIn: www.linkedin.com/company/careerstartups/
CID Student Ambassador Emily Ausubel interviews Salimah Samji, Director of the Building State Capability Program at Harvard University and Matt Andrews, Senior Lecturer in Public Policy at the Harvard Kennedy School and Faculty Associate at the same program. Matt and Salimah talk about how the Building State Capability program came about, explain us what is the Program’s core methodology and how it’s being applied by hundreds of practitioners worldwide. Interview recorded on February 23rd, 2018 // cid.harvard.edu // // bsc.cid.harvard.edu // About Salimah Samji: Salimah Samji is the Director of the Building State Capability (BSC) Program. She has over fifteen years of experience working in international development, on issues of public service delivery, transparency and accountability, strategic planning, and monitoring and evaluation. She joined CID in 2012 to help create the BSC program and is responsible for strategic planning and oversight. Salimah also leads the PDIA online courses. Prior to joining CID, she was an independent consultant working for the World Bank on issues of governance, and the Hewlett Foundation on strategic planning for one of their grantees. She has worked as a senior program manager at Google.org, leading a transparency and accountability initiative focused on empowering citizens and decision makers, by making information on service delivery outcomes, publicly available. Salimah has also worked at the World Bank as a social/rural development and monitoring and evaluation specialist in South Asia. She has a Bachelor of Mathematics from the University of Waterloo (Canada) and a Masters in Public Administration in International Development (MPAID) from the Harvard Kennedy School. She is a qualified Casualty Actuary who decided to change careers after her 18-month experience working in Afghan refugee camps with a Canadian NGO (FOCUS Humanitarian Assistance) based in Pakistan. Salimah has worked and lived in Kenya, India, Pakistan, Tajikistan, Canada and the USA. About Matt Andrews: Matt Andrews is Senior Lecturer in Public Policy. His research focuses on public sector reform, particularly budgeting and financial management reform, and participatory governance in developing and transitional governments. Recent articles focus on forging a theoretical understanding of the nontechnical factors influencing success in reform processes. Specific emphasis lies on the informal institutional context of reform, as well as leadership structures within government-wide networks. This research developed out of his work in the provincial government of Kwa-Zulu Natal in South Africa and more recently from his tenure as a Public Sector Specialist working in the Europe and Central Asia Region of the World Bank. He brings this experience to courses on public management and development. He holds a BCom (Hons) degree from the University of Natal, Durban (South Africa), an MSc from the University of London, and a PhD in Public Administration from the Maxwell School, Syracuse University.