Podcasts about magnetic resonance imaging mri

Once Dr. Ray Damadian had the idea to create a machine that used nuclear magnetic resonance to capture diagnostic data by scanning a human body, he still had to build it. And though he did, other scientists got credit for inventing the MRI.   Research: Bashir U, Rock P, Murphy A, et al. T2 relaxation. Reference article, Radiopaedia.org. https://doi.org/10.53347/rID-16494 Bellis, Mary. "A Guide to Magnetic Resonance Imaging (MRI)." ThoughtCo, Apr. 5, 2023, thoughtco.com/magnetic-resonance-imaging-mri-1992133 Bloch, Felix. “The Principle of Nuclear Induction.” Nobel Lecture. Dec. 11, 1952. https://www.nobelprize.org/uploads/2018/06/bloch-lecture-1.pdf Bloembergen, Nicolas. “Edward M. Purcell (1912-97).” Nature. April 17, 1997. https://www.nature.com/articles/386662a0.pdf Britannica, The Editors of Encyclopaedia. "Isidor Isaac Rabi". Encyclopedia Britannica, 3 Apr. 2024, https://www.britannica.com/biography/Isidor-Isaac-Rabi Britannica, The Editors of Encyclopaedia. "Paul Lauterbur". Encyclopedia Britannica, 2 May. 2024, https://www.britannica.com/biography/Paul-Lauterbur Britannica, The Editors of Encyclopaedia. "nuclear magnetic resonance". Encyclopedia Britannica, 25 Apr. 2024, https://www.britannica.com/science/nuclear-magnetic-resonance Damadian, Raymond, and Jeff Kinley. “Gifted Mind: The Dr. Raymond Damadian Story.” Master Books. 2015. Damadian R. “Tumor detection by nuclear magnetic resonance.” Science. 1971 Mar 19;171(3976):1151-3. doi: 10.1126/science.171.3976.1151 Deutsch, Claudia H. “Patent Fights Aplenty for MRI Pioneer.” New York Times. July 12, 1997. https://www.nytimes.com/1997/07/12/business/patent-fights-aplenty-for-mri-pioneer.html “Dr. Edward Purcell, 84, Dies; Shared Nobel Prize in Physics.” New York Times. March 10, 1997. https://www.nytimes.com/1997/03/10/us/dr-edward-purcell-84-dies-shared-nobel-prize-in-physics.html Drew Z, Jones J, Murphy A, et al. Longitudinal and transverse magnetization. Reference article, Radiopaedia.org (Accessed on 03 Jun 2024) https://doi.org/10.53347/rID-60738 "Edward Mills Purcell." National Academy of Sciences. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. doi: 10.17226/9977 :"Felix Bloch." National Academy of Sciences. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. doi: 10.17226/4547 LAUTERBUR, P. Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance. Nature242, 190–191 (1973). https://doi.org/10.1038/242190a0 National Academies of Sciences, Engineering, and Medicine. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. https://doi.org/10.17226/4547. National Academies of Sciences, Engineering, and Medicine. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. https://doi.org/10.17226/9977. Hofstadter, Robert. “Felix Bloch.” National Academies of Sciences, Engineering, and Medicine. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. https://doi.org/10.17226/4547. Isidor Isaac Rabi – Biographical. NobelPrize.org. Nobel Prize Outreach AB 2024. Tue. 4 Jun 2024. https://www.nobelprize.org/prizes/physics/1944/rabi/biographical/ Jones J, Howden W, Rock P, et al. T1 relaxation time. Reference article, Radiopaedia.org (Accessed on 03 Jun 2024) https://doi.org/10.53347/rID-6315 Luiten, A.L. (1999). Magnetic Resonance Imaging: A Historical Introduction. In: Magnetic Resonance Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03800-0_1 MacWilliams, B. Russian claims first in magnetic imaging. Nature426, 375 (2003). https://doi.org/10.1038/426375a “Magnetic Resonance Imaging (MRI).” National Institute of Biomedical Imaging and BioEngineering. https://www.nibib.nih.gov/science-education/science-topics/magnetic-resonance-imaging-mri “The Man Who Did Not Win.” Sydney Morning Herald. October 17, 2003. https://www.smh.com.au/national/the-man-who-did-not-win-20031017-gdhlpn.html Odeblad E, Lindström G. Some preliminary observations on the proton magnetic resonance in biologic samples. Acta Radiol Suppl (Stockholm). 2008 Aug;434:57-61. doi: 10.1080/02841850802133337 Paul C. Lauterbur – Biographical. NobelPrize.org. Nobel Prize Outreach AB 2024. Tue. 4 Jun 2024. https://www.nobelprize.org/prizes/medicine/2003/lauterbur/biographical/ Plewes, Donald B., PhD, and Walter Kucharczyk, PhD. “Physics of MRI: A Primer.” MR Physics for Clinicians. April 12, 2012. https://doi.org/10.1002/jmri.23642 Prasad, Amit. “The (Amorphous) Anatomy of an Invention: The Case of Magnetic Resonance Imaging (MRI).” Social Studies of Science, vol. 37, no. 4, 2007, pp. 533–60. JSTOR, http://www.jstor.org/stable/25474534 Purcell, E.M. et al. “Resonance Absorption by Nuclear Magnetic Moments in a Solid.” Physics Review. January 1, 1946. https://journals.aps.org/pr/pdf/10.1103/PhysRev.69.37 “Raymond Damadian.” Lemelson-MIT. https://lemelson.mit.edu/award-winners/raymond-damadian Sandomir, Richard. “Raymond Damadian, Creator of the First M.R.I. Scanner, Dies at 86.” New York Times. Aug. 17, 2022. https://www.nytimes.com/2022/08/17/science/raymond-damadian-dead.html Serai, Suraj, PhD, and Tony Dandino. “Why are MRI scans so loud?” Cincinnati Children's Radiology Department Blog. October 13, 2016. https://radiologyblog.cincinnatichildrens.org/whats-with-all-the-noise/ Sullivan, Walter. “Five Named as Winners of Lasker Medical Research Awards.” New York Times. Nov. 15, 1984. https://www.nytimes.com/1984/11/15/us/five-named-as-winners-of-lasker-medical-research-awards.html National Academies of Sciences, Engineering, and Medicine. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. https://doi.org/10.17226/9977. Wakefield, Julie. “The ‘Indomitable' MRI.” Smithsonian. June 2000. https://www.smithsonianmag.com/science-nature/the-indomitable-mri-29126670/ See omnystudio.com/listener for privacy information.

Voyageur Pharmaceuticals CEO Brent Willis joined Steve Darling from Proactive to announce that the company and Rain Cage Carbon are advancing their collaboration following the first commercial creation of a V@C60 endohedral fullerene or Vanadium atom inside a C60 molecule. Rain Cage is now embarking on the next phase of radiology drug development using their cutting-edge technology. Willis told Proactive that Rain Cage will begin working to create on a commercial scale, the encapsulation of gadolinium, bismuth, and iodine within endohedral fullerenes. This pioneering work, set to begin later this month, aims to develop a process to create Gd@C60, Bi@C60, and I@C60 endohedral fullerenes, targeting the development of highly advanced radiology contrast agents for Magnetic Resonance Imaging (MRI) and CT scans. These novel compounds, known for their rarity and complex synthesis, hold the promise of transforming medical imaging by significantly enhancing the precision and clarity of radiological scans. Endohedral fullerenes are a class of fullerenes that enclose an additional atom, ion, or cluster within their inner sphere, exhibiting superior physical and electronic characteristics compared to regular fullerenes. In the context of radiology drugs, endohedral metallofullerenes offer distinct advantages through exceptional stability and bioavailability, an amplified signal that leads to better image clarity and resolution, targeted delivery, and reduced toxicity. These properties have garnered interest in applications such as MRI contrast agents #proactiveinvestors #voyageurpharmaceuticalsltd #tsxv #vm #vyyrf #ctscan #xray #BrentWillis, #RainCage, #Nanoscience, #MRI, #CTScan, #MedicalBreakthrough, #Fullerenes, #Vanadium, #Gadolinium, #Bismuth, #Iodine, #Radiology, #MedicalInnovation, #DrugDevelopment, #Healthcare, #ScientificBreakthrough, #Nanotechnology, #MedicalResearch, #Pharmaceuticals #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Who invented the MRI? Well, that's actually tricky to say, and it is a topic that still opens debate. In this first part, we'll talk about the various developments in physics that led to the idea of an MRI machine even existing. Research: Bashir U, Rock P, Murphy A, et al. T2 relaxation. Reference article, Radiopaedia.org. https://doi.org/10.53347/rID-16494 Bellis, Mary. "A Guide to Magnetic Resonance Imaging (MRI)." ThoughtCo, Apr. 5, 2023, thoughtco.com/magnetic-resonance-imaging-mri-1992133 Bloch, Felix. “The Principle of Nuclear Induction.” Nobel Lecture. Dec. 11, 1952. https://www.nobelprize.org/uploads/2018/06/bloch-lecture-1.pdf Bloembergen, Nicolas. “Edward M. Purcell (1912-97).” Nature. April 17, 1997. https://www.nature.com/articles/386662a0.pdf Britannica, The Editors of Encyclopaedia. "Isidor Isaac Rabi". Encyclopedia Britannica, 3 Apr. 2024, https://www.britannica.com/biography/Isidor-Isaac-Rabi Britannica, The Editors of Encyclopaedia. "Paul Lauterbur". Encyclopedia Britannica, 2 May. 2024, https://www.britannica.com/biography/Paul-Lauterbur Britannica, The Editors of Encyclopaedia. "nuclear magnetic resonance". Encyclopedia Britannica, 25 Apr. 2024, https://www.britannica.com/science/nuclear-magnetic-resonance Damadian, Raymond, and Jeff Kinley. “Gifted Mind: The Dr. Raymond Damadian Story.” Master Books. 2015. Damadian R. “Tumor detection by nuclear magnetic resonance.” Science. 1971 Mar 19;171(3976):1151-3. doi: 10.1126/science.171.3976.1151 Deutsch, Claudia H. “Patent Fights Aplenty for MRI Pioneer.” New York Times. July 12, 1997. https://www.nytimes.com/1997/07/12/business/patent-fights-aplenty-for-mri-pioneer.html “Dr. Edward Purcell, 84, Dies; Shared Nobel Prize in Physics.” New York Times. March 10, 1997. https://www.nytimes.com/1997/03/10/us/dr-edward-purcell-84-dies-shared-nobel-prize-in-physics.html Drew Z, Jones J, Murphy A, et al. Longitudinal and transverse magnetization. Reference article, Radiopaedia.org (Accessed on 03 Jun 2024) https://doi.org/10.53347/rID-60738 "Edward Mills Purcell." National Academy of Sciences. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. doi: 10.17226/9977 :"Felix Bloch." National Academy of Sciences. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. doi: 10.17226/4547 LAUTERBUR, P. Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance. Nature242, 190–191 (1973). https://doi.org/10.1038/242190a0 National Academies of Sciences, Engineering, and Medicine. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. https://doi.org/10.17226/4547. National Academies of Sciences, Engineering, and Medicine. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. https://doi.org/10.17226/9977. Hofstadter, Robert. “Felix Bloch.” National Academies of Sciences, Engineering, and Medicine. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. https://doi.org/10.17226/4547. Isidor Isaac Rabi – Biographical. NobelPrize.org. Nobel Prize Outreach AB 2024. Tue. 4 Jun 2024. https://www.nobelprize.org/prizes/physics/1944/rabi/biographical/ Jones J, Howden W, Rock P, et al. T1 relaxation time. Reference article, Radiopaedia.org (Accessed on 03 Jun 2024) https://doi.org/10.53347/rID-6315 Luiten, A.L. (1999). Magnetic Resonance Imaging: A Historical Introduction. In: Magnetic Resonance Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03800-0_1 MacWilliams, B. Russian claims first in magnetic imaging. Nature426, 375 (2003). https://doi.org/10.1038/426375a “Magnetic Resonance Imaging (MRI).” National Institute of Biomedical Imaging and BioEngineering. https://www.nibib.nih.gov/science-education/science-topics/magnetic-resonance-imaging-mri “The Man Who Did Not Win.” Sydney Morning Herald. October 17, 2003. https://www.smh.com.au/national/the-man-who-did-not-win-20031017-gdhlpn.html Odeblad E, Lindström G. Some preliminary observations on the proton magnetic resonance in biologic samples. Acta Radiol Suppl (Stockholm). 2008 Aug;434:57-61. doi: 10.1080/02841850802133337 Paul C. Lauterbur – Biographical. NobelPrize.org. Nobel Prize Outreach AB 2024. Tue. 4 Jun 2024. https://www.nobelprize.org/prizes/medicine/2003/lauterbur/biographical/ Plewes, Donald B., PhD, and Walter Kucharczyk, PhD. “Physics of MRI: A Primer.” MR Physics for Clinicians. April 12, 2012. https://doi.org/10.1002/jmri.23642 Prasad, Amit. “The (Amorphous) Anatomy of an Invention: The Case of Magnetic Resonance Imaging (MRI).” Social Studies of Science, vol. 37, no. 4, 2007, pp. 533–60. JSTOR, http://www.jstor.org/stable/25474534 Purcell, E.M. et al. “Resonance Absorption by Nuclear Magnetic Moments in a Solid.” Physics Review. January 1, 1946. https://journals.aps.org/pr/pdf/10.1103/PhysRev.69.37 “Raymond Damadian.” Lemelson-MIT. https://lemelson.mit.edu/award-winners/raymond-damadian Sandomir, Richard. “Raymond Damadian, Creator of the First M.R.I. Scanner, Dies at 86.” New York Times. Aug. 17, 2022. https://www.nytimes.com/2022/08/17/science/raymond-damadian-dead.html Serai, Suraj, PhD, and Tony Dandino. “Why are MRI scans so loud?” Cincinnati Children's Radiology Department Blog. October 13, 2016. https://radiologyblog.cincinnatichildrens.org/whats-with-all-the-noise/ Sullivan, Walter. “Five Named as Winners of Lasker Medical Research Awards.” New York Times. Nov. 15, 1984. https://www.nytimes.com/1984/11/15/us/five-named-as-winners-of-lasker-medical-research-awards.html National Academies of Sciences, Engineering, and Medicine. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. https://doi.org/10.17226/9977. Wakefield, Julie. “The ‘Indomitable' MRI.” Smithsonian. June 2000. https://www.smithsonianmag.com/science-nature/the-indomitable-mri-29126670/ See omnystudio.com/listener for privacy information.

Magnetic Resonance Imaging (MRI) plays a vital role in modern healthcare diagnostics, but most Africans can't afford or access it. In this episode, I chat with Dr Johnes Obungoloch, a biomedical engineer and senior lecturer at the Mbarara University of Science and Technology, Uganda. We discuss how he and his team are developing what they call a low-field MRI system. Their dream is to democratize access to MRI across Africa. MedxTek Africa is produced and hosted by ⁠⁠Dr. Sam Oti⁠⁠, and co-edited by ⁠⁠Veronica Ojiambo⁠⁠. If you have any thoughts on this episode, or recommendations of African health innovators that you'd like us to host on the show, please reach out directly by email: sam.oti@alumni.harvard.edu or find us on Twitter or LinkedIn. Please note that the MedxTek Africa Podcast is distinct from Dr. Oti's role as a Senior Program Specialist at Canada's International Development Research Centre. The information provided in this podcast is not medical advice, nor should it be construed or applied as a replacement for medical advice. The MedxTek Africa Podcast, its production team, guests and partners assume no liability for the application of the podcast's content.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.05.05.539590v1?rss=1 Authors: Arafe, M., Bhagwat, N. P., Chatelain, Y., Dugre, M., Sokolowski, A., Wang, M., Xiao, Y., Sharp, M., Poline, J.-B., Glatard, T. Abstract: Background: The availability of reliable biomarkers of Parkinson's disease (PD)progression is critical to the understanding of the disease and development of treatment options. Magnetic Resonance Imaging (MRI) provides a promising source of PD biomarkers, however, neuroimaging results have been shown to be markedly sensitive to analytical conditions and population sampling, which motivates investigations of their robustness. This study is part of a project to investigate the replicability of 11 structural MRI measures of PD identified in a recent review. Objective: This paper attempts to reproduce (similar data, similar analysis) and replicate (variations in data and analysis) the design of the machine learning (ML) model described in [1] to predict PD progression from T1-weighted MRIs. Methods: We used the Parkinson's Progression Markers Initiative dataset (PPMI, ppmi-info.org) used in [1] and we followed as closely as possible the original methods. We also investigated slight methodological variations in cohort selection, feature extraction, ML model design, and evaluation techniques. Results: The Area under the ROC Curve (AUC) achieved by our model closely reproducing the original study remained lower than 0.5. Across all tested models, we obtained a peak AUC of 0.685, which is better than chance performance but remained lower than the AUC value of 0.795 reported in [1]. Conclusion: We managed to train a model that predicts disease progression with a performance better than chance on a cohort extracted from the PPMI dataset, using methods adapted from [1]. However, the performance of this model remains substantially lower than the one reported in [1]. Our difficulties to reproduce or replicate the original work are likely explained by the relatively low sample size in the original study. We provide recommendations on how to improve the reproducibility of MRI-based ML models of PD in the future. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.12.536600v1?rss=1 Authors: Beckers, E., Campbell, I., Sharifpour, R., Paparella, I., Berger, A., Balda, F., Koshmanova, E., Mortazavi, N., Talwar, P., Sherif, S., Jacobs, H., Vandewalle, G. Abstract: Light triggers numerous non-image forming (NIF), or non-visual, biological effects. The brain correlates of these NIF effects have been investigated, notably using Magnetic Resonance Imaging (MRI) and short light exposures varying in irradiance and spectral quality. However, it is not clear whether having light in subsequent blocks may induce carry over effects of one light block onto the next, thus biasing the study. We reasoned that pupil light reflex (PLR) was an easy readout of one of the NIF effects of light that could be used to address this issue. We characterized the sustained PLR in 13 to 16 healthy young individuals under short light exposures during three distinct cognitive processes (executive, emotional and attentional). Light conditions pseudo-randomly alternated between monochromatic orange light [0.16 melanopic Equivalent Daylight Illuminance (mel EDI) lux] and polychromatic blue-enriched white light of three different levels [37, 92, 190 mel EDI lux]. As expected, higher melanopic irradiance was associated with larger sustained PLR in each cognitive domain. This result was stable over the light block sequence under higher melanopic irradiance levels as compared to lower ones. Exploratory frequency-domain analyses further revealed that PLR was more variable within a light block under lower melanopic irradiance levels. Importantly, PLR varied across tasks independently of the light condition pointing to a potential impact of the light history and/or cognitive context on PLR. Together, our results emphasize that the distinct contribution and adaptation of the different retinal photoreceptors influence the NIF effects of light and therefore potentially their brain correlates. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Emi Gal shares the lessons he's learned building Ezra, why he tracks 150 different biomarkers, what he's learned doing a Yearly Challenge for the last 14 years, and why he's focused on achieving peak health by 40, and more. As well as the origin story behind his extreme discipline and his advice for others that want to become more disciplined. “To make progress in anything, but especially your health, you just need to nudge behavior a little bit every day. I find that tracking 150 different biomarkers does that quite well for me.” — Emi Gal EPISODE GUIDE (LINKS, QUOTES, NOTES, AND BOOKS MENTIONED) https://www.danielscrivner.com/notes/emi-gal-ezra-20-minute-playbook   FULL TEXT TRANSCRIPT https://www.danielscrivner.com/notes/emi-gal-ezra-20-minute-playbook-transcript    CHAPTERS (00:00:00) - Introduction (00:01:27) - Why and How Emi Gal Tracks 150 Different Biomarkers (00:05:50) - How Emi Gal is Reaching Peak Health by The Age of 40 (00:08:54) - The Relationship Between Bone Density and Exercise (00:10:27) - Why Emi Gal Has Done a Yearly Challenge Every Year Since 2008 (00:18:16) - Lessons Learned Studying and Becoming Antifragile (00:22:23) - Lessons Learned from Studying with a World Memory Champion (00:26:56) - Lessons Learned from Interviewing Elderly Americans (00:31:31) - Why People Would Be Surprised at Emi Gal's Discipline (00:34:06) - How to Become More Disciplined (00:39:05) - Emi Gal's Favorite Books: Antifragile and The Patient Will See You Now (00:42:57) - Emi's Advice for His Younger Self: Embrace Optionality Early On ABOUT THE GUEST Emi Gal started his first company, Brainient, when he was just 19. He spent 10 years building Brainient into one of the leading ad-tech companies in Europe before it was acquired by Teads—one of the largest advertising platforms in Europe, with 1.8-billion impressions per month. After working with Hospices for Hope, a non-profit in Romania that builds and operates hospices for terminally ill cancer patients, Emi realized that one of the biggest problems with cancer is the lack of a fast, accurate, affordable way to screen for cancer everywhere in the body. He founded Ezra in 2018 to solve this problem using Magnetic Resonance Imaging (MRI) and Artificial Intelligence. To date, he's reduced the cost of getting a full-body cancer screening by 80% and reduced the time required to get screened by 66%.

Emi Gal shares the lessons he's learned building Ezra, why he tracks 150 different biomarkers, what he's learned doing a Yearly Challenge for the last 14 years, and why he's focused on achieving peak health by 40, and more. As well as the origin story behind his extreme discipline and his advice for others that want to become more disciplined. “To make progress in anything, but especially your health, you just need to nudge behavior a little bit every day. I find that tracking 150 different biomarkers does that quite well for me.” — Emi Gal EPISODE GUIDE (LINKS, QUOTES, NOTES, AND BOOKS MENTIONED) https://www.danielscrivner.com/notes/emi-gal-ezra-20-minute-playbook   FULL TEXT TRANSCRIPT https://www.danielscrivner.com/notes/emi-gal-ezra-20-minute-playbook-transcript    CHAPTERS (00:00:00) - Introduction (00:01:27) - Why and How Emi Gal Tracks 150 Different Biomarkers (00:05:50) - How Emi Gal is Reaching Peak Health by The Age of 40 (00:08:54) - The Relationship Between Bone Density and Exercise (00:10:27) - Why Emi Gal Has Done a Yearly Challenge Every Year Since 2008 (00:18:16) - Lessons Learned Studying and Becoming Antifragile (00:22:23) - Lessons Learned from Studying with a World Memory Champion (00:26:56) - Lessons Learned from Interviewing Elderly Americans (00:31:31) - Why People Would Be Surprised at Emi Gal's Discipline (00:34:06) - How to Become More Disciplined (00:39:05) - Emi Gal's Favorite Books: Antifragile and The Patient Will See You Now (00:42:57) - Emi's Advice for His Younger Self: Embrace Optionality Early On ABOUT THE GUEST Emi Gal started his first company, Brainient, when he was just 19. He spent 10 years building Brainient into one of the leading ad-tech companies in Europe before it was acquired by Teads—one of the largest advertising platforms in Europe, with 1.8-billion impressions per month. After working with Hospices for Hope, a non-profit in Romania that builds and operates hospices for terminally ill cancer patients, Emi realized that one of the biggest problems with cancer is the lack of a fast, accurate, affordable way to screen for cancer everywhere in the body. He founded Ezra in 2018 to solve this problem using Magnetic Resonance Imaging (MRI) and Artificial Intelligence. To date, he's reduced the cost of getting a full-body cancer screening by 80% and reduced the time required to get screened by 66%.

Mike Elder interviews John Greensmyth, a ‘cancer veteran', reflects with his wife, Alison, on the brain freeze that can happen during consultations with medical staff and explores the amazing contribution made to the development of MRI scanners by an Aberdeen University research team. Among the points of interest covered in this episode are the following: Erica Banks, Communications Lead for Friends of ANCHOR, provides an update on news and events, beginning by talking about the https://www.friendsofanchor.org/index.php/news/event-will-show-how-money-has-been-spent (‘Supporter Thank You') event on Friday 7 October.  In addition, Erica draws attention to various fundraising events that are happening during October, including the https://www.aberdeencity.gov.uk/events/dance-proms-2022 (Aberdeen Dance Proms) that are taking place on Wednesday 5 and Thursday 6 October. [00:59] Mike interviews John Greensmyth, who recently took part in Brave, a fashion show featuring men from the local area who have had to deal with a cancer or haematology diagnosis. John talks about living with cancer for over thirty years and how that ‘roller coaster' ride has affected him and his family. He also describes some ways in which the Brave models supported each other and concludes by highlighting the importance of research and of treating each patient, first and foremost, as a person. (NB An extended version of John's interview will be released as a bonus episode in due course.)[05:25] In this month's foray into the Friends of ANCHOR archives, Mike shares some news stories about various fundraising activities that took place in 1997. Among the items mentioned is a barbecue, dance and raffle which put Tullynessle on the map and the initiative taken by 91 year old Effie Watson, whose ‘goal' was to ‘kick off' an auction for the charity by donating a football, signed by the Aberdeen FC squad, which she had won in a raffle. [20:22] In the ‘Finding the Words' section of this episode, Mike and Alison recall the meeting at which the consultant explained Mike's cancer diagnosis. Despite their best efforts, much of that meeting passed as a blur, so it was extremely helpful that Alison had prepared some questions and then wrote down key points covered in the meeting. [23:44] In the ‘And Finally' section, Mike highlights the fantastic contribution made to cancer diagnosis and analysis by the work of Aberdeen University scientists, who carried out the world's first Magnetic Resonance Imaging (MRI) body scan, thanks to their breakthrough development of spin-warp imaging techniques. [27:48] Suggestions or feedback about the podcast can be sent to foapodcast@freerangepodcasting.co.uk, and Mike's guest in the next episode will be Louise Budge, the Service and Commissioning Project Manager for The ANCHOR Centre, which is currently under construction at Aberdeen Royal Infirmary. [31:04] This show has been brought to you by https://www.freerangepodcasting.co.uk/ (Free Range Podcasting).

本文通过克里安摄影术和核磁共振功能成像技术两种方法来详细论述“经络”的客观存在性。以及疾病的由来、治愈、神医的踪迹等问题进行了探讨，全文干货，偏长烧脑，但却值得你花10分钟重新认知我们的健康理论体系！这是由前苏联人S.D.和 V.Kirlian（克里安）所共同发明的一种特殊照相机，利用高伏特电压的瞬间激发，将人或是物件的影像摄入底片中，而从中就可以看出该人或物的「气场」、「能量场」。克里安相机捕捉到的气场，只是人、物的最基本能量场，称以太体（Etheric）；而人体尚有不同层次的（Layers）、更高的能量体（Energy Bodies）。克里安当时认为照片上呈现的光晕是由生物能场所造成，而这种技术能捕捉到被摄物的生命能量状态。不过现在一般相信，克里安拍摄到的仅为人和物体最基本的能量场，即乙太体（以太），而人体外围尚有更高层次的能量体（能源机构）。然而克里安照片的好处在于能提早辨视出身体功能失调的部位，使它在变成疾病前早一步获得治疗。电子摄影中最有趣的现象之一，是「幽灵叶」的效果。很多科研专家，包括亚伦．德翠克（Allen Detrick）和杜明崔斯可，都发现了在生物体周围的能量场。当他们将一片叶子从中切半时，感到非常惊讶，因為他们发现被切掉的半片叶子区域，仍会放射出与原本整片叶子一样的能量场，也就是所拍到的竟是「完整的整片叶子」。即使叶子的某部份不在，一个微妙的能量场还是继续存在於原本的部位，就像原来的叶子还在一般。从针灸的理论中，我们知道，许多能量的路径是行经整个身体的。我们能够想像这些经络，就像一个比神经系统更细微的系统，某些在皮肤上的重要点位和经络上的要点，已被认定為“穴道”。这些穴道分别与不同的器官共振。经由针灸的针刺激这些穴道，或透过指压按摩，相关的器官就会被注入生命能量，也称為“气”。举例来说，用针灸的针去刺激肝经络的相关穴道或用按摩方式，都能够活化肝功能，以及与这经络有关的身体其他部位。克里安摄影能够确认中医裡的这项知识，它显示出手上某些特定的共振点，甚至就是指尖，是分别与特定经络连接在一起的。当我们在克里安相片上的某一区中发现了不寻常时，就能从手指或手的共振点，推断出能量在体内的哪个部位阻塞了。下图就是通过克里安摄影的指尖状况：在我们的实例裡：像对应於肝点的那一区，若显示出微弱的或狠强的放射能量，便可以推断肝经络或其相连的身体部份能量已產生阻塞现象。这一发现引起世界众多国家科学家的注意。本世纪80年代后，德国、日本、美国等分别对人体辉光现象作了探索和研究。实验表明，人体辉光的颜色和形状会根据人的健康状况、生理和心理活动等发生变化。当人们把手放在一种高频高压环境中时，手阳明、大肠经的部位会出现一连串明亮光斑。更让人感到奇妙的是，对刚死去的人進行测试，发现人体某些部位比其周围地区发出的光要强，而这些明亮的闪光点与中医针炙图上标明的741个穴位一致。俄国和美国科学家经过长期研究，认为人体存在着一个光导纤维系统，中医学中的针炙穴位是人体中经络系统对光最敏感的部位。这些都证明了经络穴位是客观存在的一种实体。通过克里安照相术我们几乎能肯定人体周身有许多肉眼看不见而又客观存在的物质的，这就好比伽马射线、紫外线、空气等物质，确实存在可仅能用仪器检测到，而科学认为，宇宙中的一切物质都有自己频率，即一切物质都以各自不同的频率振动着。我们人类感知器官仅仅能接受一个非常小范围内的频率，一旦某个事物真大频率超过了这个范围，就无法被人类感知了，就好比海豚之间用以交流传递信息的超声波，我们人类无法听到，只能被科技仪器探测到，这便是因为超声波的频率不在人类感知器官能接受的范围内造成的。这或许也能解释为何人类看不到鬼神、灵魂等事物吧，而人群中又有些人天生就能看到些另外空间的景象，这便是因为他们的感知器官较特殊能接受超过7.23振幅的事物造成的。核磁共振功能成像技术对于经络穴位的验证，这是一项相对较新的研究手段。我们知道，通过核磁共振成像（Magnetic Resonance Imaging，简称MRI）技术，可以得到一张人大脑的图像，并可以从不同的层面去截取，相当于把脑解剖开来一层一层的去看，看到具体的一些结构。進而，借用MRI的结构成像，可以间接的得到“功能”成像。比如我们已知左侧的大脑管着右手，右侧的大脑管着左手，当人的左手在运动时，在人的大脑的右侧的局部开始有了讯号增强，相反的，如果是人的右手在运动，就看到大脑的另一侧讯号在增强，这样的一种研究，我们就叫“功能成像”。据此，韩国的一批科学家，Zang-Hee Cho教授等，就想到能否用FMRI的方法来探讨东方人的古老的经络学说。当用光刺激人的眼睛的时候，在大脑的视神经区会看到讯号增强，这个是现在科学已知的。另外，在针灸学中，通过一些相关的穴位的刺激，可以治疗眼睛的一些疾病。医书上也有相关记载，哪些经络和穴位是与眼睛有关系的，那么这是不是与大脑联系呢？足太阳膀胱经在这脚上有四个穴位点，已知这四个穴位点对治疗眼睛的疾病有作用，实验表明，当用针对受试者的这几个穴位進行刺激的时候，也同样看到了在这个视神经区信号的增强。但是，如果将针刺在离这已知的穴位旁边，隔1厘米外的地方，受刺者在大脑视神经区，就没有发现讯号增强的现象。也就是说，必须刺在穴位点上，才会有这个效果。 读过《皇帝内经》的人或许都对某个词存在着疑惑和印象，大家知道，在《黄帝内经》中将“心、肝、脾、肺、肾”叫做“五藏”，并不是当今西方医学解剖学中的“五脏”，而如今很多中医研究者以为是汉字问题故将此问题忽略。其实不然，《黄帝内经》以及中医中所指的“五藏”并不是西方解剖学中那个看的见摸的着的人体器官，而是“藏”在另外空间人类肉眼看不到的一种象，也就是《黄帝内经素问·六节藏象论》中所述的“藏象”。相反，将中医理论与现代科技探测到的种种现象结合来看，我们似乎可以得出一个结论：这也是为何很多人身体出现了不正常状态，如失眠、便秘、乏力、脱发等，可是去医院用仪器检测西医大夫便会告诉你一切指标正常，没有任何疾病。事实上此时要是经一中医把脉便可得知身体已经出现严重问题了，但随着时间慢慢推移疾病才会显现到解剖生理系统上，一检测才发现为时已晚。那么中医的针灸等治疗原理又是什么呢？虽然不敢妄下结论，但我们同样可以做出一个假设：所谓的穴位或许就是解剖生理系统和藏象生理系统两者间的沟通点，通过针刺某穴位，便可重新激活和联通两个生理系统之间的联系，使人体回归正常状态。其实这解释起来不难，但是需要读者有较为开阔的思维以及对前沿科学一些结论的认知，上文提到频率的问题，有些人似乎就能与众不同感知到看到另外空间的景象，民间叫做“阴阳眼”。那么这个阴阳眼究竟是何物？是迷信还是能用科学解释得通呢？其实修炼界将其叫做“天目”，道家叫做“泥丸宫”，科学家叫做“松果体”（科学研究发现松果体完全具备人类眼睛的结构）这个器官直指眉心位于我们大脑的正中心，我们能看到另外空间全靠它，大部份人的松果体出生都是活跃状态的。所以总有人说小婴儿能看到常人看不见的事物这并不是什么无稽之谈，但随着成长某些观念以及业力的阻挡导致能量丢失，也就慢慢封闭了。但是有些人一直都开着，可以透视也能看到其他生命体的存在，我们通常叫做特异功能，透视遥视与天目早在上世纪就被科学界公认为几大特异功能之一。那么除了那些运气好的特异功能人士之外，还有什么办法可以激活松果体呢？可以通过打坐静修的方式。而中国也一直有“医道同源”的说法，古代修道者多半也是个好医者，好医者多半也是修道之士，其实修炼文化和理念贯穿于整个中华文明，直到近代无神论的入侵才逐渐消亡，“天时地利人和，顺应自然、做事不要违背天理、要积德别造业！比如易经64卦与DNA64个密码子的惊人对应关系，卦象与疾病的对应，八卦与计算机二進制……很多发现使人叹为观止，简直无法相信古人的智慧。既然中医理论的先进性目前已得到了科技的证实，那么大家若想得到一个健康的身体或者长寿，就不能忽视中医所讲的养生理论，我们决不能靠着西医检测的那些指标来判断身体是否处于健康状态，而是更加的了解中医文化。例如一日有十二个时辰，每个时辰都由不同的经脉和脏腑当令進行工作，该睡觉时就不要熬夜，辰时脾胃经当令就应该進食切勿赖床，该穿衣时切勿追求潮流要风度不要温度，这都是生活作息方面，而中医的根本以及精华就是修炼。《黄帝内经》中皇帝问岐伯,为何上古真人都能活120岁才归天，而晚年筋骨照样强健，现在的人为何天年未到就早衰了呢?岐伯答道，上古之真人“和于阴阳、法于术数”，懂得将自己与宇宙同化，生活完全符合宇宙阴阳运行的法则。也讲到：精神内守，恬淡虚无，病安从来？人的病追到源头无非就是业力导致，业力无非就是因人无法克制欲望而造下，人的一切痛苦源头皆是欲望与执着，倘若能把情名利看淡些不执著，病又会从哪里来呢？寂静法师曾开示过：历代的医祖医圣他们是怎么治病的？他们治病就是用智慧、用能量、用方法调动我们自身的自愈能力。如果我们自己的自愈能力没有了，那不论什么神医都束手无策，所以，我们自己就是最强大的神医！我们出生的时候这位神医就在了，他如影随形的跟随着我们，从未分开过。我们与生俱来就有神医跟随，但为什么他不上班呢？其实神医在哪里我们是能看到的。比如我们身体上划个口子流血，但不会血流不止，血会自己凝固。为什么？是我们自身的自愈能力。我们不需要告诉血液让它快凝固，伤口快愈合。我们的身体非常非常精密，有五脏六腑，有复杂严密的神经血管，还有贯通身体的经络系统，这不是妈妈决定的也不是爸爸决定的，更不是我们自己决定的，这是我们与生俱来的。我们会笑会哭会思维，为什么会思维？再比如，人把眉毛剃了它还会长，但不剃它就不长。剃了之后的眉毛就知道要开始长，长到原来的长度就会停止。又是谁在丈量眉毛的长度说长够了呢？这些都是谁在发指令？谁在控制？——就是这位神医。他的力量是最强大的。道家认为，这是“道”。佛家认为，这是如来。做个形象的比喻，自我们出生以来，这个神医就担任我们的警卫员。但是我们一直不给他发工资，不给他吃饭，也不鼓励他。他已经饿的走不动路了，所以也没有积极性，没有力气了，更不想工作。但他又被上级指定了，不能离开，只能拖着瘦弱的身体跟着我们走。这个神医不需要吃我们人所吃的物质的饭，神医需要美德、道德、功德、信仰来营养他。我们一起冥想，这就是在给神医吃饭，他很快就吃饱了，吃得壮壮实实的，特别欢喜，然后工作的积极性就提高了，一提高病就不见了，就痊愈了。这件事很有意思。病本来就不存在，“无所从来亦无所去，故名如来”。比如，你闭着眼睛被敲了一棒之后眼冒金星，过一会儿没有金星了，请问金星到哪里去了？本来就不存在，它的存在是个假象。就像气球一吹就大了，气一放就没了，请问气球去哪了？本来就不存在。来是一种表象，去也是一种表象。西医是科学，不是哲学，但中医懂哲学。从哲学的角度说，你来了就一定会去，这就是规律。规律就是你生了就一定会死，死了也一定会生。我们身上的病，它来是有原因的，它因为我们的需要而来；它走，也是有原因的，因为我们的不需要而走。生命中的一切，不管是病、名利、还是钱财，都是这样的规律，万事万物都是这样的规律。病痛反映的是佛法中的缘起规律——我们的疾病是由很多条件共同构成的，我们只要拆掉一个条件就可以让疾病走。就好比我们想让一个汽车开不了，我们不需要把整个汽车都炸了，实际上只要拆掉一个轮子或者拔掉油管，它就跑不了了。《易经》就是研究万事万物变化的规律。你去看病，医生会说，你这个部位病变了，所以说病是变出来的，是因为一些因素变来的。既然病可以变来，那就可以变走。《易经》中“易”变为一声就是“医”，“医”就是改变。比如让你不要抽烟，让你吃药住院，这些就是让你改变。任何医生都是让你改变，只有改变才能治疗,但改变的效果是不一样的。万事万物都逃不出这个规律。我们的五脏六腑必须同时存在，要是相互争功人就无法存活了。同样的道理，我们发现西医有问题就去弥补，跳着脚骂是没用的，没病都骂出病来了。我们的医圣医祖为什么这么神？就是因为他们善于调动我们内在的神医为我们治病，这是他们最大的长处。不论高明还是不高明的医生，也都是通过我们内在的神医来治疗我们。我们现在就是找到这个宝了。我们一定要学会透过现象看本质，这是一种生命的智慧，能真正帮助我们解决生命中的苦。病也是一种现象，如果可以找到病的本质，就可以对症下药治愈疾病。有很多原因可以引起疾病，但很多不同原因引起的疾病，用药物治疗的作用非常有限。所以我们把命交给药物是不对的，这是一个非常大的误区，药只是起到辅助的作用，很多病是无法用药物解决的。 其实哲学是可以治病的，伦理学也是可以治病的，王善人就是用伦理学来治病；还有心理学可以治病……所以不仅仅是药物的治疗，不仅仅是西医治疗。过去我们把康复只束缚在西医、束缚在药物这个很小的点上，是因为我们被洗脑了。但我们不是不要西医，而是要合理使用，正确利用。一些慢性病、绝症的根源是在灵魂，所以我们需要提升自己，让自己成长，心态放好，一切都会好起来的。—————————————作者：佩索阿播音：张婉琦背景音乐：大谷幸-散り逝く桜

Magnetic Resonance Imaging (MRI) has played a big role in shaping the healthcare industry's approach to detection, monitoring, and tracking of medical conditions. Since its invention in the 1970s, a lot of improvements have been made to increase its performance and accessibility. As the industry continues to digitalize, we can expect more changes that will make MRIs more powerful and efficient.The fifty-year history of MRI takes us from early plans scribbled on a napkin at a Pittsburgh Eat n' Park in 1971, through developments to increase patient comfort and image quality in the 1980s, and into a future where AI can predict, survey, and manage a patient's likelihood for dementia. In this special episode, Arthur Kaindl talks to experts in the field, Bruce Rosen, M.D., Franz Schmitt, Jürgen Hennig, and Vivek Muthurangu, M.D., about the recent and eventful history of MRI.In today's conversation, you'll hear about the development of the first MRI machine and the challenges faced by the inventors. You'll learn about the improvements that have been made and the impact that they've had on the healthcare industry, as well as what the future holds for MRI machines and what it'll take to get there.Some Questions Asked:Did you think that MRI was going to be a big innovation? (02:52)How did it feel seeing the results of a scan during the development stages? (06:56)What exactly can current MRI scanners help us see now that we couldn't see with earlier scanners? (13:11)When did you really start to see that certain problems in MRI needed fixing? (18:42)What role would you give to artificial intelligence in the future of MRI? (22:07)What have you found MRI clinicians need to do, especially when working with pediatric patients? (27:09)What You'll Learn in This Episode:How the first MRI scanner worked (04:28)The purpose of different MRI sounds (09:31)The role of MRI in the detection and tracking of neurodegenerative diseases (14:22)The impact of imaging technology on how we think about law and criminal behavior (17:13)How to make MRI scanners more accessible (24:30)The future of MRI scanners (28:46)Connect with Dr. Bruce Rosen:LinkedInConnect with Franz Schmitt:LinkedInConnect with Jürgen Hennig:University Medical Center Freiburg Connect with Vivek Muthurangu:Centre for Translational Cardiovascular ImagingConnect with Arthur Kaindl:LinkedIn Hosted on Acast. See acast.com/privacy for more information.

Hyperfine was founded with a vision to save lives by making Magnetic Resonance Imaging (MRI) more accessible and affordable. 

This episode's Community Champion Sponsor is Catalyst. To virtually tour Catalyst and claim your space on campus, or host an upcoming event: https://www.catalysthealthtech.com/ (CLICK HERE) --- Profoundly engaged in his company's purpose to improve people's health and well-being through meaningful innovation, our next guest is guided by one consistent belief: there's always a way to make life better. Kees Wesdorp, Chief Business Leader of Precision Diagnosis at Philips, joins us to discuss the global transformation he and his company is leading that is helping billions of people to live healthy and prevent disease.  Additionally, Kees shares how Philips is giving clinicians the health technology tools they need to make precision diagnoses and deliver personalized care supported by a seamless flow of data.  Join us to learn how Kees is leading his team at Philips to drive a positive societal impact for billions of people worldwide. Let's go! Episode Highlights: Kees' advice for others who are passionate about reimagining the healthcare industry  Philips' transition from a diversified conglomerate to a focused and globally-leading health-tech company What Philips' transformation has been like for Kees and his team Philips' dedication to enhancing billions of lives by 2030 About Our Guest:  Kees Wesdorp leads Philips' Precision Diagnosis business cluster, which brings together connected diagnostic systems and integrated diagnostic insights - including imaging, monitoring, laboratory, genomics and longitudinal data - to enable a clear care pathway with predictable outcomes tailored for every patient. Kees is also a member of the Royal Philips Executive Committee and jointly responsible for Diagnosis & Treatment. This cluster of businesses includes Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Advanced Molecular Imaging (AMI), Diagnostic X-Ray (DXR), Ultrasound, Enterprise Diagnostic Informatics and Precision Diagnosis Solutions (including Pathology, Oncology and neuro-radiology Solutions.) Kees joined Philips in 2017, as the General Manager of the Diagnostic Imaging business. He led the transformation of the business by increasing customer and employee engagement, renewing the product and solutions portfolio, and improving profitability. Prior to joining Philips, Kees was an executive vice president at Bain Capital and focused on driving transformation in selected Bain Capital portfolio companies. Before Bain Capital, Kees worked for NXP Semiconductors and was involved in the transformation of NXP in a variety of operational and functional roles in the business. Kees is profoundly engaged with Philips' purpose of improving the health and well-being of 2.5 billion people per year by 2030, including 400 million in underserved communities. We aim to achieve this goal in part through a dynamic combination of customer engagement, technological innovation, and business transformation. Kees is married and has four children, lives in Bloemendaal in the Netherlands. He is currently engaged in health and well-being mentoring, and enjoys running and skiing. “By advancing precision diagnosis, Philips aims to turn the most defining moments in healthcare into a clear care pathway with predictable outcomes for every patient.” -Kees Wesdorp Links Supporting This Episode: Philips website: https://www.usa.philips.com/ (CLICK HERE) Kees Wesdorp LinkedIn page: https://www.linkedin.com/in/kees-wesdorp-1697102/ (CLICK HERE) Philips Twitter page: https://twitter.com/Philips (CLICK HERE) Clubhouse handle: @mikebiselli Mike Biselli LinkedIn page: https://www.linkedin.com/in/mikebiselli (CLICK HERE) Mike Biselli Twitter page: https://twitter.com/mikebiselli (CLICK HERE) Visit our website: https://www.passionatepioneers.com/ (CLICK HERE) Subscribe to newsletter: https://forms.gle/PLdcj7ujAGEtunsj6 (CLICK HERE) Guest nomination form:... Support this podcast

Steve McQuillan, CEO of Avingtrans #AVG describes how business has remained strong in H1, trading in line with market expectations and why they have increased their strategic investment in the emerging Medtech 3D X-ray business, Adaptix. Trading Update, Notice of Results and Strategic Investment Avingtrans PLC (AIM: AVG), which designs, manufactures and supplies critical components, modules, systems and associated services to the energy, medical and industrial sectors, is pleased to announce business in the first half of the financial year has remained strong and the Company is trading in line with market expectations. At the end of the first half, Avingtrans had net cash (pre IFRS 16) in excess of £22.5m (31 May 2021: £23.3m). Notice of Results Avingtrans will publish its results for the six months ended 30 November 2021 on 23 February 2022, at which point it will provide a further update on performance. Strategic Investment Furthermore, Avingtrans is pleased to announce that it has increased its shareholding in the emerging Medtech 3D X-ray business, Adaptix Limited ("Adaptix"), by another 150,000 shares, for a total consideration of £1.5m. Avingtrans now owns 400,000 Adaptix shares, representing 11.9% of the current issued share capital. In the year to 31 March 2021, Adaptix made a loss after tax of approximately £1.1m. Further details on Adaptix can be found in the announcement released by the Company on 13 October 2021. About Avingtrans plc:  Avingtrans designs, manufactures and supplies original equipment, systems and associated aftermarket services to the energy, medical and industrial markets worldwide. Business units Hayward Tyler - Luton & East Kilbride, UK and USA, China and India Specialises in the design, manufacture and servicing of performance-critical motors and pumps for challenging environments. Energy Steel, Inc - Rochester Hills, Michigan, USA Provider of custom fabrications for the nuclear industry, specialising in: OEM parts obsolescence; custom fabrications; engineering design solutions; product refurbishment; on-site technical support. Stainless Metalcraft Ltd - Chatteris, UK and Chengdu, China Provider of safety-critical equipment for the energy, medical, science and research communities, worldwide, specialising in precision pressure and vacuum vessels and associated fabrications, sub-assemblies and systems. Booth Industries - Bolton, UK Designs, manufactures, installs and services doors and walls which can be tailored to be: blast &explosion proof; fireproof; acoustically shielded; high security/safety; or combinations of the above Ormandy Group, Bradford, UK Design, manufacturers and servicing of off-site plant, heat exchangers and other HVAC (heating, ventilation and air conditioning) products Composite Products Ltd - Buckingham, UK Centre for composite technology, parts and assemblies, serving customers in industrial markets. Magnetica Ltd - Brisbane, Australia Magnetica Limited specialises in the development of next generation MRI technologies, including dedicated extremity MRI systems and MRI system components. Magnetica has successfully built and tested a compact, integrated 3 Tesla orthopaedic MRI system, demonstrating clinical-quality imaging. Commercialisation of this system (and others) is on-going. Magnetica's structure now includes two other business units: Scientific Magnetics - Abingdon, UK Designs and manufactures superconducting magnet systems and associated cryogenics for a variety of markets including MRI and provides services for Nuclear Magnetic Resonance instruments. Tecmag Inc, Houston, USA Designs, manufactures and installs instrumentation, including consoles, system upgrades, and probes, mainly for Magnetic Resonance Imaging (MRI) and Nuclear Magnetic Resonance (NMR) systems.

Ever wonder what it's like to become a participant in a clinical research study? This podcast outlines all aspects of recruitment, vetting, protocols, and considerations for joining a study and dispels common misconceptions often fostered by Hollywood movies or TV shows. Jessica Ganga, Communications & Digital Media Coordinator at the Foundation, moderates a panel of research coordinators for mobility, spinal cord injury (SCI), stroke, and traumatic brain injury (TBI) and the Foundation's recruitment manager. They share how volunteers help Kessler Foundation further its clinical research on advancing treatments, which impact the lives of individuals with disabilities worldwide. Volunteers are the heart of our research! Learn more about the panel: Rachel Byrne, Senior Research Coordinator (SCI) https://kesslerfoundation.org/aboutus/Rachel%20Byrne Kate Goworek, Research Coordinator (Mobility) https://kesslerfoundation.org/aboutus/Kathleen%20Goworek Jenny Masmela, Senior Research Coordinator (Stroke) https://kesslerfoundation.org/aboutus/Jenny%20Masmela Sam Schmidt, Research Recruitment Manager https://kesslerfoundation.org/aboutus/Samantha%20Schmidt Angela Smith, Senior Research Coordinator (TBI) https://kesslerfoundation.org/aboutus/Angela%20Smith Frequently Asked Questions about the Foundation's Research - https://kesslerfoundation.org/research-faq Volunteers are the heart of our research! Interested in joining a study? For more information on in-person and tele-studies, go to https://kesslerfoundation.org/join-our-research-studies Definitions/Keywords ================================================= What is spatial neglect? Patients who have had a stroke or traumatic brain injury may have a neurological syndrome called spatial neglect, which affects their ability to pay attention to their surroundings and body parts on the less affected side (the left side for patients with right brain injury). Spatial neglect is disabling. Patients may 'forget' to shave, groom, or dress the left side of their bodies. They also have major problems with driving, reading, and balance. https://kesslerfoundation.org/research/stroke/rehabilitation/spatial-neglect/caregiver https://kesslerfoundation.org/research/stroke/rehabilitation/spatial-neglect/professional What is KF-NAP®? Kessler Foundation Neglect Assessment Process (KF-NAP®) is an assessment tool that may help clinicians detect the presence of spatial neglect and measure the severity of the syndrome. What is KF-PAT®? Kessler Foundation Prism Adaptation Treatment (KF-PAT®) is implemented in occupational therapy for post-stroke spatial neglect. Including prism adaptation treatment in standard of care for patients with post-stroke spatial neglect improved functional and cognitive outcomes. What is MRI contrast There are two major types of Magnetic Resonance Imaging (MRI) scans: with contrast and non-contrast. The main distinction is that for contrast MRIs, a dye (gadolinium-based) is given to the patient intravenously before the scan. Contrast is often order by a physician who wants to highlight a particular part of the body. What is HIPPA? The Health Insurance Portability and Accountability Act of 1996 (HIPAA) is a federal law that required the creation of national standards to protect sensitive patient health information from being disclosed without the patient's consent or knowledge. For more information, go to https://www.hhs.gov/hipaa/for-professionals/privacy/index.html ================================================= Tuned in to our podcast series lately? Join our listeners in 90 countries who enjoy learning about the work of Kessler Foundation. Be sure to subscribe to our SoundCloud channel “KesslerFoundation” for more research updates.

Let’s begin with a Patreon-fueled shout-out. Colder temperatures are creeping in, and now is the perfect time to think about keeping your family warm through the holidays. Make sure you are getting the most out of your home with help from your local energy nonprofit, LEAP. LEAP wants you and yours to keep comfortable all year round, and offers FREE home weatherization to income- and age-qualifying residents. If you’re age 60 or older, or have an annual household income of less than $74,950, you may qualify for a free energy assessment and home energy improvements such as insulation and air sealing. Sign up today to lower your energy bills, increase comfort, and reduce energy waste at home!On today’s program: The overall health of the James River has dropped slightly The Food and Drug Administration approves focused ultrasound to treat some symptoms of Parkinson’s diseaseArea transportation officials want your input tonight on the region’s transit futureAn update on planning for Smart Scale’s fifth round The Charlottesville Redevelopment and Housing Authority prepares its annual plan to the U.S. Department of Housing and Urban DevelopmentWhile the number of vaccinated Virginians has increased due to the extension of shots into people between the ages of 5 and 11, the number of cases has been up slightly over the past two days. However the Virginia Department of Health reports Wednesday figure of 2,592 new cases as a technical error that includes counts from previous days. The seven day average is now at 1,475 a day and the percent positivity is at 5.5 percent today. The Blue Ridge Health District reports another 49 new cases today and the fatality count is at 309. Do you have something to say about how our area bus systems should work? Tonight you’ll have your chance to weigh in on a Regional Transit Vision that could guide the future. Lucinda Shannon is a transportation planner with the Thomas Jefferson Planning District who briefed a technical committee of the Metropolitan Planning Organization on Tuesday.“I’m really hoping you guys will all sign up for the public meeting which is Thursday night at 6:30 p.m.,” Shannon said. “There’s also surveys on both of the TJPDC transit projects.”The TJPDC is also conducting a separate study of the expansion of transit in Albemarle County.Changes to the Charlottesville Area Transit system have been studied and presented to the public this year, but there is no schedule for when they may go into effect as there are more procedural steps to go through. (story map) (presentation)This week, the Norfolk City Council adopted a resolution approving a plan called Multimodal Norfolk that seeks to increase frequency of some buses. “The Recommended Network focuses 70 percent of resources on service that will maximize access to opportunity for most residents and are likely to get high ridership relative to cost,” reads the resolution adopted Tuesday night. “The other 30 percent of resources are focused on service that is not likely to get high ridership but will provide service in areas where there is relatively high need.”Service in Norfolk is provided by Hampton Roads Transit, which that city pays about $20 million a year to operate service.  That includes the Tide light rail system. Meanwhile, work continues to prepare the next round of applications for the Virginia Department of Transportation’s Smart Scale funding process.  Chuck Proctor is a planner with VDOT’s Culpeper District and he’s assisting Albemarle and the MPO come up with potential submissions.“Most of them are bike-ped related, a lot of them are multimodal projects like Avon Street, 5th Street, the 29-250 bypass,” Proctor said. Other projects that could be submitted include the intersection of Old Trail and Crozet Avenue, a recommendation from the ongoing North 29 corridor study, projects on Pantops, as well as various intersections of U.S. 250 east of Pantops. The Thomas Jefferson Planning District can submit up to four applications on behalf of localities. Proctor said he was not aware of what applications the city of Charlottesville might advance. Jeannete Janiczek, the city’s urban construction initiative. In most cases, Charlottesville administers its own projects without involvement from VDOT. “I just want to remind everyone this is still early in the process,” Janiczek said. “We have a new City Council coming online. The city does plan to apply for Smart Scale but we haven’t yet decided which projects.” In four rounds, Charlottesville has been awarded millions for various streetscape projects, none of which has yet gone to construction. In September, Council indicated they would no longer support contributing a local match for funds received for the first two phases of West Main Streetscape. VDOT has not yet been formally informed of any decision, according to spokesman Lou Hatter. Janiczek said potential Charlottesville projects for Round 5 a fourth phase of West Main Streetscape, or in the East High Street, Rose Hill, and the Preston Avenue corridors. There is no information about any of these potential projects available on the city website. In contrast, Albemarle and the TJPDC have been discussing potential projects since the spring. In recent years, Albemarle County has increased its capacity to design and build non-vehicular transportation projects. Kevin McDermott is a chief of planning.“We are now finally after many years in the construction phase for a lot of sidewalk improvements including new sidewalks out on Avon Street Extended, both north and south of the Mill Creek intersection,” McDemott said. The others are:New sidewalk along U.S. 250 near the Harris Teeter including a pedestrian crossing New sidewalk along Rio Road East from John Warner Parkway heading east and south toward CharlottesvilleNew crosswalk at Mountain View Elementary School on Avon Street ExtendedNew sidewalk and shared-use path on Lambs Road to the Lambs Land CampusNew sidewalk on Ivy Road between city limits and the UVA Musculoskeletal CenterThe U.S. Food and Drug Administration has approved the use of focused ultrasound to treat patients with Parkinson’s disease, according to a release from the University of Virginia Health System. Specifically, medical device regulators have authorized medical centers to use something called Exablate Neuro by the company Insightec to treat mobility problems associated with tremors caused by Parkinson’s disease. “Prior to the approval, available treatments for the Parkinson’s symptoms included drugs, which not all patients respond to, and invasive deep-brain surgeries,” reads the release.” Focused ultrasound, in comparison, does not require incisions or cutting into the skull.” During the procedure, highly focused sound waves are used to target faulty brain cells and used together with Magnetic Resonance Imaging (MRI), treatment can help ease symptoms. The releases stresses that this is not a cure. The medical technology has been pioneered at UVA and shepherded by the Focused Ultrasound Foundation. Other potential uses include treatment for essential  tremors, uterine fibroids and some forms of cancer.. Research is ongoing. For more information visit the UVA Health website or watch videos on the Focused Ultrasound Foundation’s YouTube page. Water quality in the James River has declined slightly over the past two years, according to a report card issued this week by an advocacy group that seeks to promote practices to reduce pollution. Since 2007, the James River Association has issued the State of the James and this year’s B- is based on a score of 61 percent. Every two years that score is factored by looking at 18 indicators split into the two categories of River Health and River Restoration Progress. In 2017 the grade was 63 percent. “The decline that has occurred since 2017 reflects the impact of abnormally high rainfall experienced across the watershed in recent years causing increased polluted runoff throughout the James,” reads the press release. “While oysters and tidal water quality showed promising resilience over the past year by bouncing back from the surge of rainwater and pollution, the river also revealed stalled progress in phosphorus, nitrogen, and sediment pollution reductions, as well as stream health.” Among the indicators are gauges of how healthy various wildlife populations are. The good news is that the bald eagle scores at 100 percent due to an increase in breeding pairs to 352, indicating the ban on DDT as well as passage of the Endangered Species Act in 1973 has led to the resurgence. The bad news is that American shad are rated at zero and efforts to stock the James River watershed with hatchery shad have not worked because of the presence of dams, water intakes for water supply, invasive catfish, and fishing nets intended for other species. “Given the dire situation, Virginia must develop an emergency recovery plan that clearly identifies restoration actions,” reads the report card. “But it will take a long-term and sustained effort to bring American shad back from the brink of collapse in the James.” To look through all of the indicators, visit the State of the James website and explore their story map. What are you most interested in? Let me know in the comments. You’re reading Charlottesville Community Engagement and it’s now time for a second Patreon-fueled shout-out. The Plant Northern Piedmont Natives Campaign, an initiative that wants you to grow native plants in yards, farms, public spaces and gardens in the northern Piedmont. The leaves have started to fall as autumn set in, and as they do, this is a good time to begin planning for the spring. Native plants provide habitat, food sources for wildlife, ecosystem resiliency in the face of climate change, and clean water.  Start at the Plant Northern Piedmont Natives Facebook page and tell them Lonnie Murray sent you!The Charlottesville Redevelopment and Housing Authority’s Board of Commissioners will hold a closed meeting today to discuss a personnel matter. Last week, the appointed body held a work session on a report the CRHA must turn in to the U.S. Department of Housing and Urban Development. Kathleen Glenn-Matthews is the deputy director of the CRHA. (FY20-FY21 adopted plan) (FY21-22 draft plan) (FY22-23 draft plan)“The public housing authority PHA plan is a pretty comprehensive guide to all of our agency’s policies and programs,” said Glenn-Matthews. “We spent a lot of time on our goals.”There are two parts to the plan, one of which is a five-year review that won’t be due until 2023. The second part is an annual plan with details about what will happen in the next fiscal year. The fiscal year for the CRHA runs from April 1 to March 30, a different calendar than the city, state, and federal government.  HUD classifies CRHA as a “troubled agency” based on the Public Housing Assessment System (PHAS) and the Section Eight Management Assessment Program (SEMAP). Glenn-Matthews said that means CRHA has to give more information in its annual plan. One of the first items in the draft plan is a listing of the number of public housing units and the number of housing choice vouchers. The number of units has dropped from 376 to 324 due in part to the temporary closure of Crescent Halls due to renovations. The number of housing vouchers has increased due to their use to provide temporary places for temporarily displaced residents. Those vouchers are separate from a program funded directly by the City of Charlottesville but administered by CRHA to increase their number. The city has had a line item of $900,000 a year in the capital budget for this supplemental program. Highlights from the past year include the adoption of policies on security cameras as well de-concentration of poverty.“The PHA’s admission policy is designed to provide for de-concentration of poverty and income mixing by bringing higher income tenants into lower income communities and lower income tenants into higher income communities,” reads a statement in the plan.Glenn-Matthews said the CRHA wants to build a homeownership program as well as augment the family self-sufficiency program.“We don’t have funding for it and we’re penalized by being troubled but we are looking at alternate sources for that and it’s definitely a big priority for us,” Glenn-Matthews said. The draft plan indicates that the CRHA will continue to engage in “mixed finance modernization or development” as well as “demolition and/or disposition” in the coming year. One project is development of between 39 and 50 units at Sixth Street SE. There is also a pending demolition and disposition application for the second phase of South First Street, which would replace 58 existing units with a larger project. Planning for redevelopment of Westhaven is expected to begin in the next fiscal year. “We want to make sure everything in this plan is there that we want to do this year because if not we’ll have to do an amendment, and nobody wants to go through the process,” Glenn-Matthews said. The plan also explains how nonprofit companies have been formed to serve to secure funding for redevelopment. There’s also data on who lives in the units. As of August 31, 76 percent of households had incomes below 30 percent of the area median income, 14 percent are between 30 and 50 percent, and three percent are between 50 and 80 percent. Six percent of households do not have their income data available. Only one percent of residents are classified as Hispanic or Latino, three percent are classified as Asian, 21 percent are white, and 75 percent are Black.There are a total of 736 people living in Charlottesville public housing and the average household size is 2.6 percent. The public hearing on the annual plan will be held on Monday, December 20. Thanks to Ting for their support in helping this program be produced each day. Today the newsletter ends with a limerick from show supporter Harry Landers honoring Ting for their commitment to match your initial payment to a paid Substack subscription!There once was a writer from C-ville,Who sought to shine light upon evil.He did his own thing,With some help from Ting.If there's news to report, we know he will.Special announcement of a continuing promo with Ting! Are you interested in fast internet? Visit this site and enter your address to see if you can get service through Ting. If you decide to proceed to make the switch, you’ll get:Free installationSecond month of Ting service for freeA $75 gift card to the Downtown Mall This is a public episode. Get access to private episodes at communityengagement.substack.com/subscribe

Steve McQuillan, CEO of Avingtrans #AVG discusses their £2.5m investment in emerging medtech leader, Adaptix whose focus is on transforming radiology, by allowing low-cost, low-dose 3D portable imaging. About Avingtrans Avingtrans designs, manufactures and supplies original equipment, systems and associated aftermarket services to the energy, medical and industrial markets worldwide. Business units: Hayward Tyler - Luton & East Kilbride, UK and USA, China and India Specialises in the design, manufacture and servicing of performance-critical motors and pumps for challenging environments. Energy Steel, Inc - Rochester Hills, Michigan, USA Provider of custom fabrications for the nuclear industry, specialising in: OEM parts obsolescence; custom fabrications; engineering design solutions; product refurbishment; on-site technical support. Stainless Metalcraft Ltd - Chatteris, UK and Chengdu, China Provider of safety-critical equipment for the energy, medical, science and research communities, worldwide, specialising in precision pressure and vacuum vessels and associated fabrications, sub-assemblies and systems. Booth Industries - Bolton, UK Designs, manufactures, installs and services doors and walls which can be tailored to be: blast &explosion proof; fireproof; acoustically shielded; high security/safety; or combinations of the above Ormandy Group, Bradford, UK Design, manufacturers and servicing of off-site plant, heat exchangers and other HVAC (heating, ventilation and air conditioning) products Composite Products Ltd - Buckingham, UK Centre for composite technology, parts and assemblies, serving customers in industrial markets. Magnetica Ltd - Brisbane, Australia Magnetica Limited specialises in the development of next generation MRI technologies, including dedicated extremity MRI systems and MRI system components. Magnetica has successfully built and tested a compact, integrated 3 Tesla orthopaedic MRI system, demonstrating clinical-quality imaging. Commercialisation of this system (and others) is on-going. Magnetica's structure now includes two other business units: Scientific Magnetics - Abingdon, UK Designs and manufactures superconducting magnet systems and associated cryogenics for a variety of markets including MRI and provides services for Nuclear Magnetic Resonance instruments. Tecmag Inc, Houston, USA Designs, manufactures and installs instrumentation, including consoles, system upgrades, and probes, mainly for Magnetic Resonance Imaging (MRI) and Nuclear Magnetic Resonance (NMR) systems.

Magnetic Resonance Imaging (MRI) has played a big role in shaping the healthcare industry's approach to detection, monitoring, and tracking of medical conditions. Since its invention in the 1970s, a lot of improvements have been made to increase its performance and accessibility. As the industry continues to digitalize, we can expect more changes that will make MRIs more powerful and efficient.The fifty-year history of MRI takes us from early plans scribbled on a napkin at a Pittsburgh Eat n' Park in 1971, through developments to increase patient comfort and image quality in the 1980s, and into a future where AI can predict, survey, and manage a patient's likelihood for dementia. In this special episode, Arthur Kaindl talks to experts in the field, Bruce Rosen, M.D., Franz Schmitt, Jürgen Hennig, and Vivek Muthurangu, M.D., about the recent and eventful history of MRI.In today's conversation, you'll hear about the development of the first MRI machine and the challenges faced by the inventors. You'll learn about the improvements that have been made and the impact that they've had on the healthcare industry, as well as what the future holds for MRI machines and what it'll take to get there.Some Questions Asked:Did you think that MRI was going to be a big innovation? (02:52)How did it feel seeing the results of a scan during the development stages? (06:39)What exactly can current MRI scanners help us see now that we couldn't see with earlier scanners? (12:54)When did you really start to see that certain problems in MRI needed fixing? (18:26)What role would you give to artificial intelligence in the future of MRI? (21:51)What have you found MRI clinicians need to do, especially when working with pediatric patients? (26:53)What You'll Learn in This Episode:How the first MRI scanner worked (04:15)The purpose of different MRI sounds (09:15)The role of MRI in the detection and tracking of neurodegenerative diseases (14:06)The impact of imaging technology on how we think about law and criminal behavior (16:56)How to make MRI scanners more accessible (24:13)The future of MRI scanners (28:29)Connect with Dr. Bruce Rosen:LinkedInConnect with Franz Schmitt:LinkedInConnect with Jürgen Hennig:University Medical Center Freiburg Connect with Dr. Vivek Muthurangu:Centre for Translational Cardiovascular ImagingConnect with Arthur Kaindl:LinkedInJürgen Hennig and Franz Schmitt received financial support from Siemens Healthineers for this collaboration. See acast.com/privacy for privacy and opt-out information.

Magnetic Resonance 3D Imaging (MRI) helps orthodontists like Airway and Sleep Group predict changes in bony or soft tissues associated with treatment, over time. Orthodontic patients are generally children and are more susceptible to the harmful effects of ionizing radiation. Airway and Sleep Group makes every effort to minimize or eliminate the exposure of our patients to ionizing radiation. A patient's ability to use MRI in orthodontic diagnosis and screening would be an important step in the right direction because it would completely eliminate the patient's exposure to ionizing radiation. MRI puts the principle of ALARA which stands for “as low as reasonably achievable” into maximum effect in terms of radiation exposure. This principle means that even if it is a small dose, if receiving that dose has no direct benefit, you should try to avoid it.Magnetic Resonance Imaging (MRI) is more accurate than Periapical X-rays for measuring tooth lengths. By understanding how well braces, oral appliances, and other therapies are working throughout the treatment plan, practitioners can make adjustments along the way to ensure a truly successful outcome. MRI imaging allows for repetitive 3-D imaging of dental structures in any age group without worrying about potential harmful radiation exposure to monitor the progress of orthodontic tooth movement.Why MRI is the best for 3D ImagingMRI is the first choice of 3D imaging for assessment for implant placement. It is now also the gold standard for temporomandibular joint (TMJ) imaging because it is used to see the soft tissue component of the joint.There are many advantages to using MRI for 3D imaging. The first is its ability to image the TMJ and disk. Secondly, an MRI can also show the display of soft and hard tissues and give you the ability to see inflammatory processes. And thirdly, MRI is also safe to use for patients who are allergic to the contrast agent and can be obtained without repositioning of the patient.How an MRI worksMRI works by recording a resonance signal from the excited hydrogen atoms created by a magnetic field. The scanner is a magnetic field surrounding the patient. Gradient coils then turn on and off to vary the magnetic field. As the magnetic field excites atoms. it senses an equilibrium state energy. The energy from radio waves and the magnetic field then gets converted to a number.  A computer processes the number and then converts that to an image. MRI images the water in the tissues.Parents considering using MRI to diagnose orthodontic issues in their children can contact Airway and Sleep Group for a referral from Dr. Lilliana Calkins. Dr. Calkins dedicates her time to improving the conditions to support facial growth and airway development. She does this through the use of craniofacial orthopedics, orofacial myology and interceptive orthodontics. Visit www.airwayandsleepgroup.com for more information.

Professor Ted Baker is the Chief Inspector of Hospitals at the Care Quality Commission (CQC). Prior to this Ted held a series of senior leadership roles and had a successful career as a clinical academic where he pioneered the use of Magnetic Resonance Imaging (MRI)  for the heart. He was also one of the key drivers behind the establishment of the Evalina Children's Hospital. In this episode we ask him about: His career Leadership Care Quality Commission Organisational culture Advice for medical students and doctors Driving Improvement: Case Studies from eight NHS trusts https://www.cqc.org.uk/sites/default/files/20170614_drivingimprovement.pdf Quality improvement in hospital trusts: Sharing learning from trusts on a journey of QI https://www.cqc.org.uk/sites/default/files/20180911_QI_hospitals_FINAL.pdf For comments, collaboration or feedback, contact us via email or Twitter. Email: medspirepodcast@gmail.com Twitter: @medspirepodcast

Magnetic Resonance Imaging (MRI) is considered one of the major innovations in the world of diagnostic radiology. By virtue of its flexible and noninvasive nature, MRI is one of the best tools we have to image the human body. However, conventional MRI scanners are gigantic machines that cost millions of dollars and weigh up to three tons - they are therefore limited in their distribution and point-of-care applicability. Wouldn't it be amazing if we could shrink conventional MRI scanners into portable machines that could be plugged in almost everywhere and provide imaging diagnostics in situations where it would otherwise be impossible? Does this sound like science fiction to you? Listen to this episode to learn how Dr. Clarissa Cooley and her collaborators at the Martinos Center for Biomedical Imaging are working on transforming room-size scanners into TV-size machines that can be transported by cart.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.19.390336v1?rss=1 Authors: Jamieson, D., McLoughlin, L. T., Beaudequin, D. A., Shan, Z., Boyes, A., Schwenn, P., Lagopoulos, J., Hermens, D. F. Abstract: Background: Adolescence is an important period for developing ones sense of self. Social connectedness has been linked to a sense of self which in turn has links to resilience in mental disorders. Adolescence is also a period of increased risk of chronic sleep deprivation during a time of ongoing white matter (WM) maturation. The complex relationship between these variables and their relationship with the onset on mental disorders during adolescence remains largely unexplored. Methods: N = 64 participants aged 12 years (M = 12.6) completed the Pittsburgh Sleep Quality Index (PSQI), Social connectedness scale (SCS) and a diffusion weighted Magnetic Resonance Imaging (MRI) scan to investigate the relationship of these variables to predict psychological distress via the Kessler psychological distress scale (K10) in early adolescents. Multiple regression analysis was used with K10 entered as the dependent variable and SCS, PSQI, and values of white matter integrity as the predictor variables. Results: Results showed that while all four variables collectively accounted for a significant proportion of the variance in K10 (41.1%), SCS and PSQI were the only predictors that accounted for a significant proportion of variance uniquely. Conclusions: These findings suggest interventions aimed at increasing levels of social connectedness and sleep quality during adolescence may reduce psychological distress. Future longitudinal reporting of this combination of variables is suggested. Copy rights belong to original authors. Visit the link for more info

Drive with Dr. Peter Attia Podcast Notes Key Takeaways Body Mass Index (BMI) is a good crude indicator of health but doesn’t account for muscle massPercentage of body fat is a more accurate indicator of health versus BMIVisceral fat, the build-up of fat around organs – is the type of fat to be concerned about and associated with metabolic syndromeRead the full notes @ podcastnotes.org In this “Ask Me Anything” (AMA) episode, Peter and Bob discuss different methods to evaluate body composition. They explore ways of measuring body fat, delineating between subcutaneous and visceral fat, and go over best strategies for improving body composition and optimizing health. They also discuss insulin resistance using a patient case study that highlights interventions capable of reversing the condition. Finally, Peter addresses his level of concern about a recent Consumer Report finding that Topo Chico had the highest levels of a class of synthetic chemicals (PFAS) of all the carbonated bottled waters tested. Peter concludes by sharing if the finding will change his consumption habits. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #17 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.   We discuss: Body mass index (BMI) vs. body fat percentage (BF%) (1:45); Methods of assessing body fat—Magnetic Resonance Imaging (MRI) (6:25); The different types of body fat (9:00); Methods of assessing body fat—Computed Tomography (CT Scan) (12:00); Methods of assessing body fat—Dual-Energy X-ray Absorptiometry (DEXA) (14:30); Methods of assessing body fat—Hydrostatic/Underwater Weighing (19:25); Methods of assessing body fat—Air Displacement (Bod Pod) (22:25); Methods of assessing body fat—Skinfold measurement (23:55); Methods of assessing body fat—Total Body Water (27:15); Methods of assessing body fat—Bioelectrical Impedance (BIA) (28:45); The optimal body fat percentage, muscle mass, and the best strategy to improve body composition (31:30); Defining insulin resistance and the steps to reverse it (40:15); Patient case study: Reversing insulin resistance (49:00); Addressing the recent finding of high levels of PFOA in Topo Chico (58:25); and More. Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/ama17  Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.

In this “Ask Me Anything” (AMA) episode, Peter and Bob discuss different methods to evaluate body composition. They explore ways of measuring body fat, delineating between subcutaneous and visceral fat, and go over best strategies for improving body composition and optimizing health. They also discuss insulin resistance using a patient case study that highlights interventions capable of reversing the condition. Finally, Peter addresses his level of concern about a recent Consumer Report finding that Topo Chico had the highest levels of a class of synthetic chemicals (PFAS) of all the carbonated bottled waters tested. Peter concludes by sharing if the finding will change his consumption habits. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #17 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.   We discuss: Body mass index (BMI) vs. body fat percentage (BF%) (1:45); Methods of assessing body fat—Magnetic Resonance Imaging (MRI) (6:25); The different types of body fat (9:00); Methods of assessing body fat—Computed Tomography (CT Scan) (12:00); Methods of assessing body fat—Dual-Energy X-ray Absorptiometry (DEXA) (14:30); Methods of assessing body fat—Hydrostatic/Underwater Weighing (19:25); Methods of assessing body fat—Air Displacement (Bod Pod) (22:25); Methods of assessing body fat—Skinfold measurement (23:55); Methods of assessing body fat—Total Body Water (27:15); Methods of assessing body fat—Bioelectrical Impedance (BIA) (28:45); The optimal body fat percentage, muscle mass, and the best strategy to improve body composition (31:30); Defining insulin resistance and the steps to reverse it (40:15); Patient case study: Reversing insulin resistance (49:00); Addressing the recent finding of high levels of PFOA in Topo Chico (58:25); and More. Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/ama17  Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.

Macaroni, Macarena, and Magnets. What do all these things have in common? Find out in this episode as Alastair explains the science behind Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI). Just try not to get dizzy as we spin 'round and 'round! https://linktr.ee/notyetadr Edited by: Sienna Questions or Suggestions? Email us at phd32b@gmail.com

Giving men as much information as possible to guide them in their decision-making is vital. So, today, it's our pleasure to welcome Dr. Rajan Gupta, a radiologist from Duke University, to talk about Magnetic Resonance Imaging (MRI) of the prostate. Currently, MRI is being used more and more in various clinical scenarios for the prostate. Be sure to listen in today to find out more! Dr. Gupta is the first radiologist to be interviewed on this podcast! He is Division Chief of Abdominal Imaging at Duke University, and he is Director of Imaging for the newly-created Duke Cancer Institute Center for Prostate and Urologic Cancers. Dr. Gupta has been a prolific and productive researcher in the area of genitourinary oncology, and he is a nationally recognized expert in prostate MRI. We are very fortunate to have Dr. Gupta with us on the show today, so stay tuned to find out all you need to know about MRI of the prostate. Disclaimer: The Prostate Health Podcast is for informational purposes only. Nothing in this podcast should be construed as medical advice. By listening to the podcast, no physician-patient relationship has been formed. For more information and counseling, you must contact your personal physician or urologist with questions about your unique situation.  Show highlights: What MRI is, and how it works. MRI requires no radiation. MRI was used on the prostate first in the early 1980s, but it only took off when the technology improved in the last ten to fifteen years. Dr. Gupta explains what has led to MRI taking off in the past ten to fifteen years. Dr. Gupta describes some of the different scenarios where a prostate MRI could be useful. Using MRI to help guide targeted or fusion biopsies. The goal of MRI in various scenarios. Dr. Gupta answers a question that is frequently asked by men who have not had a prior prostate biopsy. Whether or not patients should have a biopsy before getting imaging. In Europe, there are movements geared to promote MRI as a means by which patients with elevated PSAs can get imaging first, in favor of targeted biopsies rather than traditional biopsies. What the advocates for prostate cancer patients need to be thinking about, regarding insurance companies and treatment decisions. What to expect when preparing for an MRI. Links and resources: Follow Dr. Pohlman on Twitter and Instagram - @gpohlmanmd  Get your free What To Expect Guide (or find the link here, on our podcast website)   Join our Facebook group     Dr. Rajan T. Gupta Duke Cancer Institute

Join the Beyond the Books hosts as they talk with Dr. Steven Beyea, Scientific Director of the Biomedical Translational Imaging Centre at the IWK and QEII Health Centres, about his work using Magnetic Resonance Imaging (MRI) to study the brains of COVID-19 patients, and how he got into research.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.28.120774v1?rss=1 Authors: Kashyap, R., Bhattacharjee, S., Arumugam, R., Oishi, K., Desmond, J. E., Chen, S. A. Abstract: Background: Transcranial Direct Current Stimulation (tDCS) is a technique where a weak current is passed through the electrodes placed on the scalp. The distribution of the electric current induced in the brain due to tDCS is provided by simulation toolbox like Realistic-volumetric-Approach-based-Simulator-for-Transcranial-electric-stimulation (ROAST). However, the procedure to estimate the total current density induced at the target and the intermediary region of the cortex is complex. The Systematic-Approach-for-tDCS-Analysis (SATA) was developed to overcome this problem. However, SATA is limited to standardized headspace only. Here we develop individual-SATA (i-SATA) to extend it to individual head. Method: T1-weighted images of 15 subjects were taken from two Magnetic Resonance Imaging (MRI) scanners of different strengths. Across the subjects, the montages were simulated in ROAST. i-SATA converts the ROAST output to Talairach space. The x, y and z coordinates of the anterior commissure (AC), posterior commissure (PC), and Mid-Sagittal (MS) points are necessary for the conversion. AC and PC are detected using the acpcdetect toolbox. We developed a method to determine the MS in the image and cross-verified its location manually using BrainSight. Result: Determination of points with i-SATA is fast and accurate. The i-SATA provided estimates of the current-density induced across an individuals cortical lobes and gyri as tested on images from two different scanners. Conclusion: Researchers can use i-SATA for customizing tDCS-montages. With i-SATA it is also easier to compute the inter-individual variation in current-density across the target and intermediary regions of the brain. The software is publicly available. Copy rights belong to original authors. Visit the link for more info

Paul talks with consultant cardiologist Dr Sanjay Gupta on a subject that he specialises in, cardiac imaging. Dr Gupta takes us through the various tools that he uses such as echocardiogram, computerised tomography (CT) scanning and Magnetic Resonance Imaging (MRI) scanning. Dr Gupta explains everything about these techniques that patients need to know and also talks about how future tools may help prevent the main cause of sudden cardiac adeaths - heart attacks. Presented and edited by Paul Swindell. Recorded March 2020. See acast.com/privacy for privacy and opt-out information.

A new study suggests that bad dreams can prepare people for fear-causing situations. In a study published in the journal Human Brain Mapping, neuroscientists from the University of Geneva, the University Hospitals of Geneva in Switzerland, and the University of Wisconsin in the United States looked into the brains' reaction to different types of dreams. The scientists discovered that people who experience bad dreams react more effectively to frightening situations when awake. The scientists subjected 18 participants to an experiment using a method called high-density electroencephalography (EEG), in which the subjects' brain activities were monitored using electrodes placed on their skulls. Then, the scientists woke the participants up several times during the night and asked if the subjects experienced dreams and if these dreams involved fear. After comparing the participants' answers with their brain activity, the scientists found that specific areas of the brain that control emotions are activated depending on the nature of the dream. To find out more about these brain areas and their roles, the scientists conducted another experiment with 89 participants who were asked to keep a week-long dream diary. Afterward, they were shown disturbing images while inside a Magnetic Resonance Imaging (MRI) scanner. Based on the findings, the area of the brain regulating emotional responses to fear was more effective in participants who experienced bad dreams than in those who had a peaceful sleep. The scientists concluded that bad dreams seem to be beneficial, and they hope the findings could help create new methods of dream-related therapies that can help people combat anxiety. However, the scientists cautioned that once a bad dream becomes a terrible nightmare, the effects will be counterproductive because sleep will be interrupted.

  The authors analyzed data from nearly 3,000 breast MRI exams administered at the Baltimore institution between 2011 and 2016. They pinpointed 185 individuals who met the study’s criteria, with a provider labeling them as BI-RADS category 3.  About 57% of study subjects received their follow-up examination in a timely fashion within 10 months, and another 18% did so after a slightly longer period of time. Meanwhile, about 24%, or 45 individuals, never visited for their follow-up MRI.    Women initially deemed to have a less than 2% chance of developing breast cancer often skip the recommended follow-up MRI six months later. Johns Hopkins researchers are attempting to understand why, and recently published some early insights into the issue. They estimated that about 24% of patients categorized as a 3 in the Breast Imaging Reporting and Data System (BI-RADS) did not return for their re-examination. Factors fueling that failure included high out-of-pocket expenses and a lack of any past history of breast cancer in the family, according to the study, published Oct. 8 in the Journal of the American College of Radiology. BIRADS 3 often indicates the need for a 6-month follow-up mammogram. ... If a mammogram is classified into the BI-RADS category 3 it tends to have a very low positive predictive value (less than 2%), meaning the chance of being diagnosed with breast cancer is low. “Our data suggest that there may be subsets of patients who would benefit from additional support and resources to help increase their likelihood to follow through with recommended short-interval follow-up,” concluded Emily Ambinder, MD, a Johns Hopkins radiology instructor, and colleagues. Those could include automated reminders or more concerted communication after the visit, they wrote. The authors analyzed data from nearly 3,000 breast MRI exams administered at the Baltimore institution between 2011 and 2016. They pinpointed 185 individuals who met the study’s criteria, with a provider labeling them as BI-RADS category 3. About 57% of study subjects received their follow-up examination in a timely fashion within 10 months, and another 18% did so after a slightly longer period of time. Meanwhile, about 24%, or 45 individuals, never visited for their follow-up MRI. Ambinder and colleagues found no connection between sociodemographic factors (i.e., race, marital status, living situation) and compliance. However, they did find that women with higher out-of-pocket expenses tended not to return; noncompliant patients averaged $352 compared to $83 for compliant. Having a family or personal history with breast cancer also made patients more likely to return for an MRI six or so months later, they found. Reasons for the initial examination are also important. For instance, half of the patients who presented to their doctor for “problem solving” were noncompliant with the follow-up MRI. That’s compared to 60% compliance for women who underwent high-risk screenings. There are several noted limitations of the study, according to the authors. The study population was small at just 185 and confined to only Johns Hopkins, and the authors were not able to obtain out-of-pocket costs or education for all subjects. BI-RADS Category System BIRADS or ‘BI-RADS stands for Breast Imaging Reporting and Data System and was established by the American College of Radiology. BI-RADS is a scheme for putting the findings from mammogram screening (for breast cancer diagnosis) into a small number of well-defined categories. Although BIRADS started out for use with breast screening mammography, it was later adapted for use with Magnetic Resonance Imaging (MRI) and Breast Ultrasound as well. BI-RADS 1 means that the mammogram was negative (ie, no cancer) and that you should continue your routine screening. BI-RADS 2 mean? BI-RADS 2also means that your mammogram was normal (i.e. no cancer), but other findings (such as cysts) are describ...

Laura Finucane of the National Health Service (United Kingdom) is interviewed by Kevin L. MacPherson regarding a publication titled, “What is the diagnostic accuracy of red flags related to cauda equina syndrome (CES), when compared to Magnetic Resonance Imaging (MRI)? A systematic review.”

Anita Waxman, co-founder and director of Ceras Health, has been involved with healthcare technology and the development of new modalities that have changed the course of medicine over the past thirty-five years. In 1975, Anita founded and served as CEO and Chairman of Howe-Lewis International, a management consulting and executive search firm. Howe-Lewis serves the biotechnology, medical electronics, and healthcare communities. It is dedicated to healthcare and not-for-profit communities and is retained by its clients to recruit the entire range of executive-level talent. From its founding, Howe-Lewis has demonstrated its commitment to partnering with both major, established institutions and with emerging, growing organizations to identify and attract the very best leaders.    In 1977, Anita was the co-founder of Diasonics Inc., the company that introduced both diagnostic ultrasound and Magnetic Resonance Imaging (MRI) to market. Diasonics was at the forefront in changing the way that medical imaging could diagnose disease. In 1984, Anita along with Dr. Nicholas Cummings founded American Biodyne Inc. She served on the board of directors through its growth and sale to Medco Containment Services (later acquired by Merck). Along with KKR, Merck Behavioral went through a leveraged buyout and as a freestanding company (known as Merit Behavioral) its revenues grew to over $800 million. The company was later sold to Magellan Behavioral Care. Ms. Waxman served on the Board of Directors of SOS International, a worldwide medical service company that, working in some of the most inhospitable places on earth, offered international standards of medical care where it was otherwise not available, or where cultural or language barriers prevented its proper implementation. Through her involvement with SOS International, Ms. Waxman became a Director and Co-Founder of International Medical Care, Ltd., which is a rapidly growing Geneva based company that staffs and operates family practice outpatient clinics and provides emergency room health services throughout the world. Currently, Anita is a cofounder, director, and consultant to Ceras Health, which is dedicated to reducing the cost of healthcare. Ceras Health, Inc.TM (Ceras Health) has developed a patent pending SaaS platform, I'M HOME!®, that supports patients' adherence to pre-and post-discharge care plans, provides patients and care team members with the ability to measure and track patient health data, and enables individuals to get better and stay better by providing access to condition specific health information.   In addition to her work in the healthcare industry, Anita has spent many years following her passion in the world of live theater. Anita Waxman is a multiple Tony Award-winning producer. As CEO of Alexis Productions, she has garnered seventy-one Tony nominations and sixteen Tony awards. Anita is currently working with Jimmy Buffett, Frank Marshall, and Grove Entertainment to bring Escape To Margaritaville, a musical based on the music of Jimmy Buffett, to the world's stage. Anita is also producing Little Dancer, a musical based on the story of Edward Degas. Through Alexis Productions, Anita produced and won multiple Tonys for The Real Thing written by Sir Tom Stoppard, and the successful revival of Cabaret starring Natasha Richardson and Alan Cumming. Other productions include Jesus Christ Superstar, Becoming Chaplin, Rocky, the Tony Award winning Best Revival of One Flew Over the Cuckoo's Nest, The Music Man, A Moon for the Misbegotten starring Gabriel Byrne, The Wild Party, The Waverly Gallery, Electra, A Night in November, A Little Night Music, Enron, American Idiot, Love Never Dies, Present Laughter starring Frank Langella, Mrs. Klein starring Uta Hagen, Wild Honey starring Sir Ian McKellen, The Vertical Hour, Bombay Dreams, Gypsy, the West End productions of Ragtime, the Broadway revival of Rodger and Hammerstein's Flower Drum Song, the hit revival of Noises Off, The Elephant Man starring Billy Crudup, and many more. Two of her shows have won Pulitzer prizes: The Young Man from Atlanta and Top Dog/Underdog. She is a member of the Broadway League. Ms. Waxman founded two theatrical investment funds, Alexis Fund I and Alexis Fund II. Some investments include Kinky Boots (NYC, London & Tour), Escape to Margaritaville, Hello Dolly, The Front Page, Glass Menagerie, Les Liaisons Dangereuses, Jersey Boys (AUS), Book of Mormon (AUS), Verso Truth in Deception, and Joan of Arc. She is currently producing Little Dancer, a new musical by Stephen Flaherty and Lynn Ahrens staring Tiler Peck and Terrence Mann, and Directed by Susan Stroman. Other upcoming projects include a new musical based on the music of Diane Warren, The Library, Terra Firma and more. She has served on the boards of the Donmar Warehouse in London, 5th Avenue Theatre in Seattle, The Magic Theatre in San Francisco, The Roundabout Theatre Company New York City, the Human Rights watch, SOS International, and American Biodyne.   Anita Waxman has also worked with orphanages around the world. Through her foundation NOAH'S ARK, she established a home for orphaned children in Russia: the Passin-Waxman Center for Children, which is known today as Anita's Kids, which has helped to educate and care for several hundred children in the past eighteen years. 

On this week's The Sci-Files, your hosts Chelsie and Danny interview Faryal Mir and Kate Hammond from the Department of Radiology in order to understand their research on engineering Magnetic Resonance Imaging (MRI) proteins as well as the mentorship that occurs in the labs here at MSU.Faryal is associated with the Department of Genetics and the College of Osteopathic Medicine, pursuing a DO-PhD. Kate is a recent graduate of MSU and will be attending the College of Osteopathic Medicine in the fall. They work closely together in the Molecular and Cellular Imaging Laboratory (MCIL) with advisor Dr. Erik Shapiro.Faryal's work focuses on protein engineering in the context of MRI. She is very interested in exploring the liver transport protein, OATP (organic anion transporting polypeptide). She even published a paper involving OATPs. In this paper, the Shapiro lab demonstrated that a mouse with human OATPs mimic the human protein thereby making it easier for MRIs to capture an image of the animal's muscles and organs. Overall, by using human OATPs, screening animals is easier because the MRI shows greater contrast.Kate has been involved in many different projects, from investigating proteins with Faryal to running CT-based experiments and performing tissue cultures. She has been with the MCIL as an undergrad for three years and hopes to remain involved in research throughout her medical studies and career.Kate and Faryal both believe strongly in the value of mentor-mentee relationships, and feel that such a relationship benefits both people involved!If you're interested in talking about your MSU research on the radio or nominating a student, please email Chelsie and Danny at scifiles@impact89fm.org. Check The Sci-Files out on Twitter @SciFiles89FM and Facebook!

Peg Nopoulos, M.D. is Professor of Psychiatry, Pediatrics and Neurology. She is the DEO and Chair of the Department of Psychiatry at the University of Iowa Hospitals in Iowa City, Iowa. Dr Nopoulos is a physician-scientist. Her clinical care consists of taking care of patients with Huntington’s Disease in Iowa’s HD Center of Excellence where she has worked for the past 15 years. Dr. Nopoulos’ research focuses on the study of brain and behavior. This is done using state of the art neuroimaging techniques, specifically Magnetic Resonance Imaging (MRI). Dr. Nopoulos is interested in aspects of understanding normal healthy brain such as differences in brain structure and function between the sexes as well as understanding how the brain changes with development through adolescence. In regard to HD, she is interested in studying the effects of the Huntington’s gene on brain development and is director of the Kids-HD and Kids-JHD program. The Kids-HD program evaluates brain structure and function in children at risk for HD and the Kids-JHD program is the first ever neuroimaging study of JHD subjects.

Magnetic Resonance Imaging (MRI) can be used to provide quantitative measurements in the form of imaging biomarkers. These measurements have a number of attractive characteristics: They are non-invasive, can provide organ and lesion localisation of morphology, physiology and metabolism and can be repeated over time. These characteristics enable monitoring of the biological impact of drugs and can be helpful in patient selection. With appropriate deployment they can assist in go/no-go decision making and in some cases can provide endpoints for late stage trials. This episode describes the deployment and potential benefit of MRI biomarkers via a number of examples of their use in drug development in different disease areas. Original article by Dr Geoff J.M. Parker If you'd like to view the original article then follow the link below: https://www.ddw-online.com/enabling-technologies/p305520-magnetic-resonance-imaging-(mri)-in-drug-development.html You can also download the original article pdf here: https://www.ddw-online.com/media/32/100469/seeing-within-magnetic-resonance-imaging.pdf For more information on Drug Discovery World, head to: https://www.ddw-online.com

“If we read an article in the newspaper presenting two opposing viewpoints, we assume both have validity, and we think it would be wrong to shut one side down. But often one side is represented only by a single ‘expert’.” In this episode of Made You Think, Neil and I discuss Merchants of Doubt: How a Handful of Scientists Obscured the Truth on Issues from Tobacco Smoke to Global Warming, by Naomi Oreskes and Erik M. Conway. In this book, Oreskes and Cornway talk about media and science, and scientific consensus that became controversial in the public eye — from the SDI to tobacco to global warming. “Rome may not be burning, but Greenland is melting, and we are still fiddling. We all need a better understanding of what science really is, how to recognize real science when we see it, and how to separate it from the garbage.” We cover a wide range of topics, including: The tobacco industry and the regulations on smoking today Global Warming and all its many causes. Are all causes equally serious? How media talks about science and creates controversial topics out of scientific consensus The SDI and nuclear winter The sugar industry vs working out And much more. Please enjoy, and be sure to grab a copy of Merchants of Doubts by Naomi Oreskes and Erik M. Conway! Links from the Episode Mentioned in the show Flatgeologists [0:49] Strategic Defense Initiative [2:05] DDT Pesticide [2:19] The Sugar Film (2014) [06:05] Neighbourhood Effect [16:27] Tragedy of the Commons [16:27] Magnetic Resonance Imaging – MRI [18:30] Toshiba Corporation [18:30] Yamaha Corporation [18:30] The Spacex Launch [19:10] Black Mirror: Men Against Fire [22:06] Jordan Peterson’s interview on Channel 4 [26:24] Futurama: Crimes of the Hot [27:58] Mutual Assured Destruction Doctrine [32:30] CFC – Chlorofluorocarbons and Ozone depletion [38:06] Philip Morris USA [51:50] Krispy Kreme [53:48] Moore’s Law [1:14:08] Books mentioned Amusing Ourselves to Death by Neil Postman [1:13] (Nat’s Notes) (book episode) The Gospel of Wealth by Andrew Carnegie [15:14] Principles: Life and Work by Ray Dalio [18:42] (Nat’s Notes) (book episode) Command and Control: Nuclear Weapons, the Damascus Accident, and the Illusion of Safety by Eric Schlosser [31:40] 12 Rules for Life by Jordan Peterson [1:07:16] (Nat's Notes) (Neil's Notes) (book episode) The Rational Optimist: How Prosperity Evolves by Matt Ridley [01:09:35] (Nat's Notes) People mentioned Naomi Oreskes Erik M. Conway Elon Musk [1:05] [28:00] [39:30] (on this podcast) Michelle Obama [10:25] Andrew Carnegie [15:07] Adolf Hitler [21:34] Jordan B. Peterson [21:27] (on this podcast) Nassim Nicholas Taleb [27:08] (on this podcast) Ronald Reagan [31:18] Richard Feynman [35:20] Freeman Dyson [35:34] Carl Sagan [36:43] S. Fred Singer [42:16] Show Topics 0:44 — Science and media. Topics that have become controversial in the public sphere, through media, that weren’t so within the scientific community; tobacco, the sugar industry, pesticides, etc. 03:58 — The sugar industry and its history of media deception; people’s perceptions on sugar, then and now. The industry’s attempts of bettering their images as sugar is more and more seen as unhealthy. 07:21 — Sugar and artificial sugar: its effects on your body and microbiota. The inexistent proofs that help losing weight. 09:16 — What about exercise? The food industries’ attempts to shift responsibility for health and fitness into “lack of exercise”, overblowing the importance of exercising. 11:05 — Two issues that are not necessarily separated by the book: on one hand, people should be better informed of the risks of their behaviors, like eating sugar, or drinking. On the other hand, should they not be allowed to engage in certain behaviors? Or simply have awareness of the risks if they do engage? Advocating for control, instead of banning, like the taxing on the tobacco industry. 13:15 — The public perception of tobacco as incredibly dangerous, and different perspectives in different countries. 15:21 — The conclusion of the book helps understands the author’s overall thesis. Many people who fought back against restrictions to industries had been Cold War veterans, looking to protect free market. There are certain areas in which free market doesn’t work, like air quality. 17:47 — Regulation is the mother of innovation: they force people to create new solutions, often starting from the beginning. 20:05 — Surprisingly, Hitler banned cigarettes once it was known they were lethal. He had various issues with what he considered “dirty” or “unclean”, which links back to his view of the people he persecuted. 22:35 — All the Nazi research regarding smoke got discredit following their defeat, since no one wanted to use nazist research. But were there such qualms about other research, like rocket science? Is it ethic at all to use research created unethically? 24:06 — Likewise, many studies for controversial topics just can’t be conducted for ethical reasons, or at times there’s too many variables. Epidemiology is useful in this case; though correlation doesn’t necessarily means causation. 25:55 — Climate change, and how its many causes often get simplified to just one problem. And even if we’re wrong about its causes, isn’t it too dangerous to ignore the chance human intervention is responsible? 29:41 — Good science focuses on what’s not yet known; but media often then latches on to these doubts, advertising what scientist don’t know and obscuring the science of what they do know. 30:48 — The SDI: Reagan's program against nuclear strikes through satellites. Was it a serious project? Was it a proposital rumor? Could it have started a nuclear war? How did the idea get so far when it had such opposition? 35:10 — Richard Feynman, Freeman Dyson, and their views on nuclear winter and global warming: two issues that were somehow conflated. Were the models being used accurate? 36:34 — Scientists often focus on areas of doubt, rather than what is already known. A topic largely discussed in the book is that scientists aren’t necessarily good at understanding public policy, media, or how to get their ideas across to the public and vice-versa. 38:06 — CFCs. Once again, many factors contributed to the damage to the ozone layer, but all were given equal weight when certain factors were much more damaging than others. The same was done regarding skin cancers, where many other factors were pointed out that were true, but not as relevant. This seems to be a common tactic to detract from central issues. 43:58 — Second-handed smoking and e-cigarettes: are they as dangerous as regular cigarettes? What of second-hand damages that come with alcohol, like drunk driving? Should alcohol and driving be more strictly regulated? 51:05 — The companies knew what they were doing: memos from tobacco companies show their strategy of trying to keep the doubt on whether or not cigarettes were bad for your health. The ethical dilemma around working for such companies. 54:46 — School’s approach to drug education: are abstinence arguments really effective, or are them increasing drug use? Alternative methods for decreasing drug use and its harmful effects. 01:00:45 — Global Warming is still very much a current issue. What arguments that are in vogue today could be misinformation? It can be difficult to find a balance between suspecting statements that challenge the current scientific consensus, and not completely shutting them down. 01:05:00 — The book has a critical stance on Capitalism and Technology. “Technology won’t save us”. However, it is possible to join business and sustainability. 01:09:30 — The book has a certain one-sided point of view, which can be true for most of the topics discussed, but can also be a dangerous attitude. Radical changes are also much more difficult to execute, such as suddenly switching entirely away from fossil fuels. 01:12:24 — Alternatives to developing without fossil fuels. What about nuclear power? Could that be a solid green alternative? Can solar power progress as fast as our technological needs? 01:18:05 — Sponsors time. You can support us by going through our Amazon sponsored link, and buy iPads for your family, Louis Vuitton bag, or maybe puppies in the future. Use Perfecto Keto for all your keto needs. Try the Coffee Flavored Exogenous Ketones and the MCT oil powders. Try their new MCT oil to help you achieve perfect hair. “If you stop using shampoo, your hair starts being a barometer of your health”. Kettle & Fire’s bone broths will help you keep up your health, and you can put it in your hair, if you want! And Four Sigmatic for all your mushroom coffee needs and reduce your caffeine intake, though unfortunately it will not help you achieve the perfect hair. Check always our Support page. If you enjoyed this episode, don’t forget to subscribe at https://madeyouthinkpodcast.com  

Thomas C. Reed, Former Secretary of the Air Force, gave a lecture on "A History of Nuclear Proliferation: Iran Today" at The Institute of World Politics on February 9, 2016. ------ Thomas C. Reed was the Secretary of the Air Force during the Ford and Carter administrations. In the mid-Seventies, Reed became the youngest-ever director of the National Reconnaissance Office. In the Eighties, Reed served as Special Assistant to President Reagan for National Security Policy. Reed has a technical background in nuclear weapons design. After earning a graduate degree from the University of Southern California, Reed moved to a position at Lawrence Livermore National Laboratory, where he designed two thermonuclear devices, both of which were fired over the Pacific in 1962. Upon leaving Livermore, Reed started and ran a successful high-tech company making superconductors, now principally used in Magnetic Resonance Imaging (MRI) scanners. In 1966 he became the Northern California chair of Ronald Reagan's first gubernatorial race. Reed served as chief of personnel in the Governor's first administration, and in 1970 he assumed full responsibility for Governor Reagan's re-election as his statewide co-chair and campaign director. In 1973, Reed was recruited to manage certain intelligence projects at the Pentagon in connection with the Yom Kippur War. A decade of involvement in national security matters followed, culminating with a position on President Reagan's National Security Council staff. His first book, At the Abyss: An Insider's History of the Cold War-- with an introduction by former President George H. W. Bush-- was published in 2004. His second work, The Nuclear Express: A Political History of the Bomb and Its Proliferation, was co-authored by Danny Stillman, a former chief of technical intelligence at Los Alamos. Reed's third non-fiction work,The Reagan Enigma, was released in 2014.

This is a podcast by Dr Robert-Jan de Vos, sports physician in the Erasmus Medical Centre in the Netherlands, with Guustaaf Reurink, who is a registrar in Sports medicine in the Netherlands and is currently finishing his thesis on diagnosis and treatment of acute hamstring injuries. Recently, he published a paper in the New England Journal of Medicine about the role of Platelet-rich Plasma (PRP) treatment for acute hamstring injuries (http://www.nejm.org/doi/full/10.1056/NEJMc1402340). We start with discussing this interesting study, which did not show a benefit of PRP injections in acute hamstring injuries. Dr Reurink expresses the methods and results of this study and possible explanations for these findings are debated. Dr Reurink also performed a number of studies on the value of clinical tests and Magnetic Resonance Imaging (MRI) in acute hamstring injuries. Previously, he already showed that most MRIs are still abnormal when the athlete already returned to gameplay (http://bjsm.bmj.com/content/early/2013/11/19/bjsports-2013-092450.abstract?eaf). We close by discussing the role of MRI and standardised clinical tests as a predictor of time to return to play and re-injury.

Monday, January 28, 2013 at 3:30 pm PT/5:30 CT/6:30 ET Our incredible special guest tonight is Dr. Peg Nopoulos from University of Iowa Hospitals and Clinics where her primary clinical work has been working in the HD Center of Excellence. She is currently a professor in Psychiatry, Pediatrics and Neurology and she is an active faculty member of our Neuroscience Graduate Program. In 2001 she developed a program, the Iowa Medical Student Research Program that she continues to direct. She is an accomplished researcher focusing on understanding brain and behavior, using state of the art brain imaging techniques, specifically Magnetic Resonance Imaging (MRI). Dr. Nopoulos is interested in aspects of understanding normal healthy brain such as differences in brain structure and function between the sexes as well as understanding how the brain changes with development through adolescence. She was our incredible special guest on April 23, 2012 http://www.blogtalkradio.com/help4hd/2012/04/23/the-jhd-view-with-dr-peg-nopoulos where we discussed her most recent research program Kids-HD for children, adolescents, and young adults who are at-risk for Huntington's Disease and tonight we get to hear an update of the study. Ages 6-18 are invited to participate in this Brain Imaging Study at the University of Iowa Hospitals and Clinics.  

Dr Daniel Bulte, Research Lecturer, explains how Magnetic Resonance Imaging (MRI) works and introduces his research at the Oxford Centre for Functional MRI of the Brain (FMRIB).

Dr Kate Watkins, University Lecturer, discusses her research into stuttering, which makes use of MRI scans.

Monday, April 23, 2012 at 3:30 pm PST/6:30 pm EST Dr. Peg Nopoulos is with the University of Iowa and her primary work has been working in Neuropsychiatry at the HD Center of Excellence at the UI Hospitals and Clinics. Her research focuses on understanding brain and behavior, using state of the art brain imaging techniques, specifically Magnetic Resonance Imaging (MRI). She is here to talk to us about a recent brain imaging research study in children, adolescents and young adults who are at-risk for Huntington's disease.

2 SUMMARY Pathologically-anatomical and immunhistochemistric investigation of ischemic myocardium in the pig Background: Different degrees of histological alteration have been seen in hibernating myocardium. Hibernation is associated with structural myocardial changes, which involve both the cardiomyocytes and the cardiac interstitium. The purpose of this study is to investigate the effects of chronic myocardial ischemia on histological patterns to understand the underlying mechanism of hibernation. Methods: A model of ischemic injury was produced in 16 pigs (German land breed) by placement of a modified stent graft in the left anterior descending artery (LAD), which initially produced 75% stenosis, followed by a slow complete occlusion. Wall motion abnormalities were investigated by Magnetic Resonance Imaging (MRI) and ultrasound images at day 7 after implantation. Metabolism and perfusion were imaged by Positron Emission Tomography (PET) at day 7 (group 1) and at day 28 (group 2). After PET images the animals were sacrificed and tissue samples were taken for histology. Results: Viability in PET is defined by a relative decrease in perfusion in an area where there is a relative increase in FDG (fluorodeoxyglucose) concentration. This is often referred to as a “mismatch” pattern. In the study nearly all pigs showed this “mismatch” in the LAD area. The following significant results could be found in the mismatched samples: the accumulation of collagen (0,12 ± 0,12 %, p < 0,05) in LAD samples compared to those taken from remote area (0,02 ± 0,02 %) and glycogen rich perinuclear zones in LAD samples (0,06 ± 0,03 %, p < 0,05). Despite the difficulties of reproducing a long-term hibernating myocardium in an animal model, one pig (No.8) demonstrated physiological alterations that can be compared to those of human beings with hibernating myocardium. After 28 days the artery of the pig was completely occluded. A mismatch was determined by PET, and wall motion abnormalities were present. Furthermore in cells which were exposed to a repetitive ischemia, a small degree of fibrosis and glycogen richness were shown. Conclusion: In contrast to various short-term hibernating myocardium models, no equivalent model exists for long-term hibernating myocardium over a time period of weeks or months yet. For this reason, the complete mechanism of chronic hibernating myocardium is still unclear. The fluent transition of the different heart failure up to the infarct as seen in the clinic reflect the dynamic process, the interindividuell differences and last but not least the reduced compensation abilities of the heart. Due to this it is difficult to find a matching in-vivo model that shows the same mechanism as humans. Therefore every small and large animal model is helpful for clarification.