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4X Thicker Hair? Gynostemma pentaphyllum Clinical Trial Results Ep. 1233 MAR 2025A recent randomized, double-blind, placebo-controlled clinical trial published in Nutrients (2025) investigated the therapeutic potential of Gynostemma pentaphyllum extract for enhancing hair health. The study involved participants experiencing hair thinning. After 24 weeks, the Gynostemma pentaphyllum group showed a threefold increase in hair elasticity and density and a fourfold increase in hair diameter compared to the placebo group. Additionally, participants reported better outcomes in terms of reducing hair damage and dryness. These findings suggest that Gynostemma pentaphyllum extract may offer a natural and effective approach to promoting hair health. Disclaimers:"This information is for educational purposes only and should not be interpreted as medical advice.""The study discussed was conducted on a specific population experiencing hair thinning. Further research may be needed to confirm these findings in broader populations and to understand the long-term effects.""Always consult with a qualified healthcare professional before starting any new supplement or treatment regimen, especially if you have a medical condition or are taking medications.""This channel does not provide medical advice."Channel ID: UCSxq36i1g2yb-GdmNq77U7w#GynostemmaPentaphyllum #HairHealth #HairLoss #ClinicalTrial #NaturalRemediesLee J, Jin Y, Zhang X, Kim M, Koh A, Zhou S, Lee C, Seo M, Kim S, Jo S, et al. Therapeutic Potential of Gynostemma pentaphyllum Extract for Hair Health Enhancement: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2025; 17(5):767. https://doi.org/10.3390/nu17050767Gynostemma pentaphyllum, jiaogulan, hair loss, hair growth, hair density, hair thickness, clinical trial, natural hair remedies, hair thinning, supplement, hair health, study results, randomized controlled trial, double-blind, placebo controlled, hair follicle count, hair shaft diameter, herbal remedies, nutrition, hair care, scalp health, androgenetic alopecia, alopecia, natural treatment, botanical extracts, nutrients, hair revitalization

Descubre los mejores alimentos para una piel radiante y joven. Aprende cómo la nutrición combate el envejecimiento, reduce la inflamación y protege tu piel desde adentro. ¡Secretos antiaging basados en ciencia! #drmauinforma #doctormauinforma Suscríbete a este podcast en tu plataforma favorita.  Suscríbete a mi boletín informativo en: www.drmauriciogonzalez.com/ Redes sociales: ⁣ YouTube: /@doctormauinforma Instagram: www.instagram.com/dr.mauriciogonzalez TikTok: www.tiktok.com/@drmauriciogonzalez Twitter: www.twitter.com/DrMauricioGon CONTACTO ► booking@drmauriciogonzalez.com ¡Nos escuchamos pronto!⁣ Fuentes: Trevino, J., et al. (2021). "The effects of diet on skin health: An overview of recent research." Nutrition and Health, 27(2), 157-167. Bonsi, R., et al. (2020). "The Role of Nutritional Interventions in Skin Health and Aging." Dermato-Endocrinology, 12(1), e1811026. Bartoszewska, S., et al. (2019). "The Impact of Diet on the Skin and Skin Aging." Journal of Clinical Medicine, 8(9), 1430. Pugliese, P. (2019). "Diet and Skin Health: The Role of Antioxidants in Preventing Skin Aging." International Journal of Molecular Sciences, 20(8), 2018. Xia S, Zhang X, Zheng S, Khanabdali R, Kalionis B, Wu J et al. An update on inflamm-aging: mechanisms, prevention, and treatment. J Immunol Res. 2016; 2016: 8426874. Learn more about your ad choices. Visit megaphone.fm/adchoices

Neste episódio, conversamos sobre Sepse e a importância do antibótico. Salientamos pontos importantes, fatores de risco e dicas para escolha da terapia correta, principalmente no contexto de gram negativos MDR. Este é o terceiro episódio da nossa série especial realizada em parceria com a Pfizer, em que trazemos discussões que conectam ciência e prática clínica para enfrentar desafios no combate às infecções.

This week we talk about all things bone health on the podcast.  From what foods to eat to improve bone health and reduce the risk of hip fractures, to the calcium 'thieves' hidden in our diets, to exercise and much much more.  Dr. Rajiv Bajekal (MS, FRCS Orth., MCh Orth., IBLM) is a Consultant Spinal Surgeon based in London with over 35 years of expertise in Orthopaedics and Spinal Surgery. Specialising in the lumbar spine, he has a deep focus on managing conditions such as sciatica, low back pain, spinal stenosis, osteoporotic fractures, and infections. Dr. Bajekal prioritizes holistic and often non-surgical solutions for patients in severe pain, combining his surgical knowledge with his expertise as a Board-Certified Lifestyle Medicine Practitioner. A strong advocate for lifestyle medicine, Dr. Bajekal has personally experienced the transformative benefits of a whole-food, plant-based diet and incorporates these principles into his practice.  Dr. Bajekal has contributed to the UK's first plant-based nutrition course at Winchester University, where he developed a module on bone health and osteoporosis. He also co-authored a chapter on bone health in the academic book Plant-Based Nutrition in Clinical Practice. Passionate about education, he is known for making complex spinal topics accessible and engaging. For more information, visit www.rajivbajekal.com and follow him on Instagram @drrajivbajekal Relevant studies:1. Tong, T.Y.N., Appleby, P.N., Armstrong, M.E.G. et al. Vegetarian and vegan diets and risks of total and site-specific fractures: results from the prospective EPIC-Oxford study. BMC Med 18, 353 (2020). https://doi.org/10.1186/s12916-020-01815-3 2.     Gómez-Cabello A, Ara I, González-Agüero A, Casajús JA, Vicente-Rodríguez G. Effects of training on bone mass in older adults: a systematic review. Sports Med. 2012;1;42(4):301-25. 3.  Messina M. Soy and Health Update: Evaluation of the Clinical and Epidemiologic Literature. Nutrients. 2016;8(12):754. Published 2016 Nov 24. doi:10.3390/nu8120754 4.  Sahni S, Mangano KM, McLean RR, Hannan MT, Kiel DP. Dietary Approaches for Bone Health: Lessons from the Framingham Osteoporosis Study. Curr Osteoporos Rep. 2015;13(4):245-255. doi:10.1007/s11914-015-0272-1 5.  Qiu, Rui & Cao, Wen-ting & Tian, Hui-yuan & He, Juan & Chen, Gengdong & Chen, Yu Ming. (2017). Greater Intake of Fruit and Vegetables Is Associated with Greater Bone Mineral Density and Lower Osteoporosis Risk in Middle-Aged and Elderly Adults. PLOS ONE. 12. e0168906. 10.1371/journal.pone.0168906.6.  Wallace TC. Dried Plums, Prunes and Bone Health: A Comprehensive Review. Nutrients. 2017 Apr 19;9(4):401. doi: 10.3390/nu9040401. PMID: 28422064; PMCID: PMC5409740.7.  Sahni S, Mangano KM, McLean RR, Hannan MT, Kiel DP. Dietary Approaches for Bone Health: Lessons from the Framingham Osteoporosis Study. Curr Osteoporos Rep. 2015 Aug;13(4):245-55. doi: 10.1007/s11914-015-0272-1. PMID: 26045228; PMCID: PMC4928581.8.  Laird E, Ward M, McSorley E, Strain JJ, Wallace J. Vitamin D and bone health: potential mechanisms. Nutrients. 2010 Jul;2(7):693-724. doi: 10.3390/nu2070693. Epub 2010 Jul 5. PMID: 22254049; PMCID: PMC3257679.9.  Bolland M J, Avenell A, Baron J A, Grey A, MacLennan G S, Gamble G D et al. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis BMJ 2010; 341 :c3691 doi:10.1136/bmj.c369110.  Bolland MJ, Grey A, Avenell A, Gamble GD, Reid IR. Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis. BMJ. 2011 Apr 19;342:d2040. doi: 10.1136/bmj.d2040. PMID: 21505219; PMCID: PMC3079822.11.  Li K, Kaaks R, Linseisen J, et alAssociations of dietary calcium intake and calcium supplementation with myocardial infarction and stroke risk and overall cardiovascular mortality in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition study (EPIC-Heidelberg)Heart 2012;98:920-92512.  Price CT, Langford JR, Liporace FA. Essential Nutrients for Bone Health and a Review of their Availability in the Average North American Diet. Open Orthop J. 2012;6:143-149. doi:10.2174/187432500120601014313.  Bawa S. The significance of soy protein and soy bioactive compounds in the prophylaxis and treatment of osteoporosis. J Osteoporos. 2010 Mar 8;2010:891058. doi: 10.4061/2010/891058. PMID: 20981338; PMCID: PMC295724114.  Zhang X, Shu X, Li H, et al. Prospective Cohort Study of Soy Food Consumption and Risk of Bone Fracture Among Postmenopausal Women. Arch Intern Med. 2005;165(16):1890–1895. doi:10.1001/archinte.165.16.189015.  Tucker KL, Morita K, Qiao N, Hannan MT, Cupples LA, Kiel DP. Colas, but not other carbonated beverages, are associated with low bone mineral density in older women: The Framingham Osteoporosis Study. Am J Clin Nutr. 2006 Oct;84(4):936-42. doi: 10.1093/ajcn/84.4.936. PMID: 17023723. 16.  Chen L, Liu R, Zhao Y, Shi Z. High Consumption of Soft Drinks Is Associated with an Increased Risk of Fracture: A 7-Year Follow-Up Study. Nutrients. 2020;12(2):530. Published 2020 Feb 19. doi:10.3390/nu1202053017.  Cheraghi Z, Doosti-Irani A, Almasi-Hashiani A, Baigi V, Mansournia N, Etminan M, Mansournia MA. The effect of alcohol on osteoporosis: A systematic review and meta-analysis. Drug Alcohol Depend. 2019 Apr 1;197:197-202. doi:10.1016/j.drugalcdep.2019.01.025. Epub 2019 Feb 27. PMID: 30844616.18.  Chang HC, Hsieh CF, Lin YC, Tantoh DM, Ko PC, Kung YY, Wang MC, Hsu SY, Liaw YC, Liaw YP. Does coffee drinking have beneficial effects on bone health of Taiwanese adults? A longitudinal study. BMC Public Health. 2018 Nov 20;18(1):1273. doi: 10.1186/s12889-018-6168-0. PMID: 30453911; PMCID: PMC6245613.19.  Benedetti, Maria Grazia & Furlini, Giulia & Zati, Alessandro & Letizia Mauro, Giulia. (2018). The Effectiveness of Physical Exercise on Bone Density in Osteoporotic Patients. BioMed Research International. 2018. 1-10. 10.1155/2018/4840531.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-405 Overview: It's estimated that between 40%-60% of women report some degree of sexual dysfunction, which can have a significant impact on an individual's quality of life and personal relationships. Even though most clinicians understand the importance and relevance of female sexual dysfunction (FSD), they may not be aware of its prevalence, effective treatments, or how best to inquire about it. Join us as we discuss this condition, its impact on women, and evidence on effective treatments. Episode resource links: Cristine Homsi Jorge, Kari Bø, Camila Chiazuto Catai, Luiz Gustavo Oliveira Brito, Patricia Driusso, Merete Kolberg Tennfjord. Pelvic floor muscle training as treatment for female sexual dysfunction: a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology. Volume 231, Issue 1, 2024,Pages 51-66.e1,ISSN 0002-9378, https://doi.org/10.1016/j.ajog.2024.01.001.(https://www.sciencedirect.com/science/article/pii/S0002937824000061) Davis, SR. Sexual dysfunction in women. New England Journal of Medicine. V 391. N 8; P 736-745. https://www.nejm.org/doi/full/10.1056/NEJMcp2313307 Johnson, Isabella MS; Thurman, Andrea Ries MD; Cornell, Katherine A. BS; Hatheway, Jessica MBA; Dart, Clint MS; Brainard, C. Paige MD; Friend, David R. PhD; Goldstein, Andrew MD. Preliminary Efficacy of Topical Sildenafil Cream for the Treatment of Female Sexual Arousal Disorder: A Randomized Controlled Trial. Obstetrics & Gynecology ():10.1097/AOG.0000000000005648, June 18, 2024. | DOI: 10.1097/AOG.0000000000005648 Kamrul-Hasan, A.B.M, Hannan, M A A, Muhammad S, M, Aalpona, Fatema, T Z, Nagendra, L., Selim, S,  Dutta, D, D. Role of flibanserin in managing hypoactive sexual desire disorder in women: A systematic review and meta-analysis. Medicine 103(25):p e38592, June 21, 2024. | DOI: 10.1097/MD.0000000000038592 Yao H, Zhang X, Sun F, Tang G, Wu J, Zhou Z. The efficacy of intravaginal electrical stimulation (IVES) in treating female with urinary incontinence symptom from meta-analysis of nine randomized controlled trials. Front Neurol. 2022;13:933679. Published 2022 Sep 13. doi:10.3389/fneur.2022.933679 Huang H, Ding G, Li M, Deng Y, Cheng Y, Jin H.(2023) Menopause and stress urinary incontinence: The risk factors of stress urinary incontinence in perimenopausal and postmenopausal women. J Obstet Gynaecol Res. 49(10): 2509–2518. https://doi.org/10.1111/jog.15742 Tunn, R., Baessler, K., Knüpfer, S., & Hampel, C. (2023). Urinary Incontinence and Pelvic Organ Prolapse in Women. Deutsches Arzteblatt international, 120(5), 71–80. https://doi.org/10.3238/arztebl.m2022.0406 Guest: Susan Feeney, DNP, FNP-BC, NP-C, Jill M. Terrien, PhD, ANP-BC Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-405 Overview: It's estimated that between 40%-60% of women report some degree of sexual dysfunction, which can have a significant impact on an individual's quality of life and personal relationships. Even though most clinicians understand the importance and relevance of female sexual dysfunction (FSD), they may not be aware of its prevalence, effective treatments, or how best to inquire about it. Join us as we discuss this condition, its impact on women, and evidence on effective treatments. Episode resource links: Cristine Homsi Jorge, Kari Bø, Camila Chiazuto Catai, Luiz Gustavo Oliveira Brito, Patricia Driusso, Merete Kolberg Tennfjord. Pelvic floor muscle training as treatment for female sexual dysfunction: a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology. Volume 231, Issue 1, 2024,Pages 51-66.e1,ISSN 0002-9378, https://doi.org/10.1016/j.ajog.2024.01.001.(https://www.sciencedirect.com/science/article/pii/S0002937824000061) Davis, SR. Sexual dysfunction in women. New England Journal of Medicine. V 391. N 8; P 736-745. https://www.nejm.org/doi/full/10.1056/NEJMcp2313307 Johnson, Isabella MS; Thurman, Andrea Ries MD; Cornell, Katherine A. BS; Hatheway, Jessica MBA; Dart, Clint MS; Brainard, C. Paige MD; Friend, David R. PhD; Goldstein, Andrew MD. Preliminary Efficacy of Topical Sildenafil Cream for the Treatment of Female Sexual Arousal Disorder: A Randomized Controlled Trial. Obstetrics & Gynecology ():10.1097/AOG.0000000000005648, June 18, 2024. | DOI: 10.1097/AOG.0000000000005648 Kamrul-Hasan, A.B.M, Hannan, M A A, Muhammad S, M, Aalpona, Fatema, T Z, Nagendra, L., Selim, S,  Dutta, D, D. Role of flibanserin in managing hypoactive sexual desire disorder in women: A systematic review and meta-analysis. Medicine 103(25):p e38592, June 21, 2024. | DOI: 10.1097/MD.0000000000038592 Yao H, Zhang X, Sun F, Tang G, Wu J, Zhou Z. The efficacy of intravaginal electrical stimulation (IVES) in treating female with urinary incontinence symptom from meta-analysis of nine randomized controlled trials. Front Neurol. 2022;13:933679. Published 2022 Sep 13. doi:10.3389/fneur.2022.933679 Huang H, Ding G, Li M, Deng Y, Cheng Y, Jin H.(2023) Menopause and stress urinary incontinence: The risk factors of stress urinary incontinence in perimenopausal and postmenopausal women. J Obstet Gynaecol Res. 49(10): 2509–2518. https://doi.org/10.1111/jog.15742 Tunn, R., Baessler, K., Knüpfer, S., & Hampel, C. (2023). Urinary Incontinence and Pelvic Organ Prolapse in Women. Deutsches Arzteblatt international, 120(5), 71–80. https://doi.org/10.3238/arztebl.m2022.0406 Guest: Susan Feeney, DNP, FNP-BC, NP-C, Jill M. Terrien, PhD, ANP-BC Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Pedro Magno e Kaue Malpighi falam sobre o passo a passo da prescrição de rivaroxabana e apixabana: quando indicar? o que orientar o paciente? qual dose tomar? Tudo nesse episódio! No Guia TdC comentamos sobre como reverter o sangramento associado aos DOACs. Você pode ler esse tópico gratuitamente, basta clicar no link abaixo e fazer o login: Manejo de Sangramento Maior em Pacientes em Uso de Anticoagulante Oral | Guia TdC (tadeclinicagem.com.br) Referência: Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J. 2020;41(4):543-603. doi:10.1093/eurheartj/ehz405 Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) [published correction appears in Eur Heart J. 2021 Feb 1;42(5):507. doi: 10.1093/eurheartj/ehaa798] Siontis KC, Zhang X, Eckard A, et al. Outcomes Associated With Apixaban Use in Patients With End-Stage Kidney Disease and Atrial Fibrillation in the United States [published correction appears in Circulation. 2018 Oct 9;138(15):e425. doi: 10.1161/CIR.0000000000000620]. Circulation. 2018;138(15):1519-1529. doi:10.1161/CIRCULATIONAHA.118.035418 Holt A, Strange JE, Rasmussen PV, et al. Bleeding Risk Following Systemic Fluconazole or Topical Azoles in Patients with Atrial Fibrillation on Apixaban, Rivaroxaban, or Dabigatran. Am J Med. 2022;135(5):595-602.e5. doi:10.1016/j.amjmed.2021.11.008 Beyer-Westendorf J, Siegert G. Of men and meals. J Thromb Haemost. 2015;13(6):943-945. doi:10.1111/jth.12973

In this episode, Ashleigh and Rachel answer a listener's question about a recent study claiming that high leucine (and dietary protein) intake can cause atherosclerosis or cardiovascular disease. The links below provide more information on the study and their response.  The ladies also chat about some recent injuries, Ashleigh's upcoming trip to San Diego, and more. If you have questions, comments, feedback, or want to add a topic for "Ashleigh's Rant Corner," send it to musclescience4women@gmail.com. This episode is brought to you by Paleovalley. They make amazing healthy snacks, like 100% grassfed and fermented beef sticks and Superfood bars made with bone broth protein and packed with plant-based superfoods (while still managing to taste like a delicious treat). They also have a range of real-food supplements, like Fish Roe and an Organ Complex. This company doesn't cut corners, they combine the best that plants and animals have to offer for our health, and it shows - get 15% off your order at https://paleovalley.com/musclescience Sign up for our new Strong & Sculpted Shoulders workshop: https://www.rgfit.com/shoulders Get fit with us in 2024 - sign up for the Grow Your Glutes Workshop: https://www.rgfit.com/glutes  Or our flagship strength training program, Muscle Science for Women: http://www.musclescienceforwomen.com  Link to the study discussed in this episode: 1. Zhang X, Kapoor D, Jeong SJ, et al. Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk. Nat Metab. 2024;6(2):359-377. Link to Dr. Peter Attia's response, also mentioned: https://peterattiamd.com/protein-and-ascvd/  

In this episode of BackTable OBGYN, renowned reproductive endocrinologist and minimally invasive gynecologic surgeon Dr. Charles (Chuck) Miller delves into the topic of isthmoceles, a common yet often overlooked complication of C-sections, and shares his best practices for repair. Dr. Miller shares his extensive experience in diagnosing and treating isthmoceles, discussing various surgical techniques including hysteroscopic, laparoscopic, and robotic-assisted resection. He emphasizes the importance of an aggressive surgical approach for achieving higher success rates in terms of future fertility and resolving symptoms such as abnormal bleeding. Moreover, Dr. Miller highlights the need for standardized treatment protocols and reflects on the mentorship, the ongoing journey of learning and adapting in medicine, and the noble profession of healthcare. The episode offers insightful perspectives on a lesser-known gynecologic issue, underscores the value of experience and mentorship in medicine, and advocates for concerted efforts toward establishing best practices in surgical procedures. --- SHOW NOTES 00:00 - Introduction 07:18 - Defining Isthmocele and the History of Isthmocele 10:00 - The Diagnosis of Isthmocele and Its Impact on Fertility 19:31 - Exploring Surgical Techniques for Isthmocele Repair 27:54 - Understanding Hysteroscopic Resection 30:12 - Addressing C-Section Ectopics and Isthmocele Repairs 36:46 - Adapting the Surgical Approach to Different Patient Scenarios 39:35 - Postoperative Complications and Safety Measures 40:55 - The Future of Isthmocele: Surgical Standardization 50:51 - Closing Thoughts and Acknowledgements --- RESOURCES Ban Y, Shen J, Wang X, Zhang T, Lu X, Qu W, Hao Y, Mao Z, Li S, Tao G, Wang F, Zhao Y, Zhang X, Zhang Y, Zhang G, Cui B. Cesarean Scar Ectopic Pregnancy Clinical Classification System With Recommended Surgical Strategy. Obstet Gynecol. 2023 May 1;141(5):927-936. doi: 10.1097/AOG.0000000000005113. Epub 2023 Apr 5. PMID: 37023450; PMCID: PMC10108840.

Vitamins for the Management of Nail Disease: A Literature Review. Lipner S, Curtis K. Skin Appendage Disorders, 2023 Nov.Nail Psoriasis in China: A Prospective Multicentre Study. Wang S, Zhu J, Wang P, Dong J, Li Y, Shi D, Wang H, Huang X, Zhang X, Yu B, Yang Z. Journal of the European Academy of Dermatology and Venerology. 2023 Dec 15.

If you operate for long enough, chances are you will come across the unique, and potentially daunting scenario of operating on a pregnant patient. If, and when, you do, would you know what to do? Join University of Washington and MIS faculty Drs. Andrew Wright, Nicole White, and Nick Cetrulo, and residents Drs. Ben Vierra and Paul Herman as they discuss non-obstetric surgery in the pregnant patient so that you will be better informed when the challenge arises. Hosts: 1. Andrew Wright, UW Medical Center—Montlake and Northwest, @andrewswright 2. Nick Cetrulo, UW Medical Center—Northwest, @Trules25 3. Nicole White, UW Medical Center—Northwest, @NicoleWhiteTho1 4. Paul Herman, UW General Surgery Resident PGY-3, @paul_herm 5. Ben Vierra, UW General Surgery Resident PGY-2 Learning Objectives 1. Describe important physiologic changes in pregnancy that are relevant for the surgeon to know. 2. Review the epidemiology of non-obstetric general surgery in the pregnant patient. 3. Discuss specific imaging considerations in the pregnant patient. 4. Become more familiar with the technical aspects of approaching a typical surgical case in a pregnant patient. References 1. Pearl, J.P., Price, R.R., Tonkin, A.E. et al. SAGES guidelines for the use of laparoscopy during pregnancy. Surg Endosc 31, 3767–3782 (2017). https://doi.org/10.1007/s00464-017-5637-3 2. Vasileiou G, Eid AI, Qian S, Pust GD, Rattan R, Namias N, Larentzakis A, Kaafarani HMA, Yeh DD; EAST Appendicitis Study Group. Appendicitis in Pregnancy: A Post-Hoc Analysis of an EAST Multicenter Study. Surg Infect (Larchmt). 2020 Apr;21(3):205-211. https://pubmed.ncbi.nlm.nih.gov/31687887/ 3. Dongarwar D, Taylor J, Ajewole V, Anene N, Omoyele O, Ogba C, Oluwatoba A, Giger D, Thuy A, Argueta E, Naik E, Salemi JL, Spooner K, Olaleye O, Salihu HM. Trends in Appendicitis Among Pregnant Women, the Risk for Cardiac Arrest, and Maternal-Fetal Mortality. World J Surg. 2020 Dec;44(12):3999-4005. https://pubmed.ncbi.nlm.nih.gov/32737556/ 4. Fong ZV, Pitt HA, Strasberg SM, Molina RL, Perez NP, Kelleher CM, Loehrer AP, Sicklick JK, Talamini MA, Lillemoe KD, Chang DC; California Cholecystectomy Group. Cholecystectomy During the Third Trimester of Pregnancy: Proceed or Delay? J Am Coll Surg. 2019 Apr;228(4):494-502.e1. https://pubmed.ncbi.nlm.nih.gov/30769111/ 5. Hong J, Yang J, Zhang X, Su J, Tumati A, Garry D, Docimo S, Bates AT, Spaniolas K, Talamini MA, Pryor AD. Considering delay of cholecystectomy in the third trimester of pregnancy. Surg Endosc. 2021 Aug;35(8):4673-4680. https://pubmed.ncbi.nlm.nih.gov/32875420/ 6. ACOG Committee Opinion No. 775: Nonobstetric Surgery During Pregnancy. Obstet Gynecol. 2019 Apr;133(4):e285-e286. https://pubmed.ncbi.nlm.nih.gov/30913200/ 7. Ashbrook M, Cheng V, Sandhu K, Matsuo K, Schellenberg M, Inaba K, Matsushima K. Management of Complicated Appendicitis During Pregnancy in the US. JAMA Netw Open. 2022 Apr 1;5(4):e227555. https://pubmed.ncbi.nlm.nih.gov/35426921/ 8. Capella CE, Godovchik J, Chandrasekar T, Al-Kouatly HB. Nonobstetrical Robotic-Assisted Laparoscopic Surgery in Pregnancy: A Systematic Literature Review. Urology. 2021 May;151:58-66. https://pubmed.ncbi.nlm.nih.gov/32445766/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out other Behind the Knife minimally invasive surgery episodes: https://behindtheknife.org/podcast-category/minimally-invasive/

Review on Chemical Peels for Nail Surface Rejuvenation. Lam W, Tosti A. Skin Appendage Disord. 2023 Aug;9(4):237-240A New Method to Treat Onychopapilloma with Pulsed Dye Laser Irradiation: A 13-case series report. Fan X, Li T, Zhang X, Yang J, Cui J, Dou W, Yin Y, Yang Q, Xue P, Liu B, Li Y. Journal of Dermatological Treatment. 2023 Dec 31;34(1):2213363.

Dr. Nayantara Coelho-Prabhu, Mayo Clinic gastroenterologist specializing in the care of patients with gastrointestinal bleeding and endoscopy, talks through many aspects of acute GI bleeding. She helps to clarify the prioritization of medications, when to incorporate imaging, broadens our differentials for upper and lower GI bleeding, gives mindblowing advice on stool guiac testing and SO much more in this over-stuffed (or should we say constipated) chapter of Always on EM. There is also a special cameo from Dr. Luke Wood going over how to insert a Minnesota tube (esophageal balloon tamponade device)!   CONTACTS X - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch Email - AlwaysOnEM@gmail.com   RECOMMENDATION: Dieulafoy lesion video from New England Journal of Medicine: https://youtu.be/tzJQDen1nug?si=zOmywZ1VN3VvA004    REFERENCES: Drescher MJ, Stapleton S, Britstone Z, Fried J, Smally AJ. A call for reconsideration of the use of fecal occult blood testing in emergency medicine. Journal of Emerg Med. 2020. 58(1)54-58 Mathews BK, Ratcliffe T, Sehgal R, Abraham JM, Monash B. Fecal Occult Blood testing in hospitalized patients with upper gastrointestinal bleeding. Journal of Hospital Medicine. 2017. 12(7)567-569 Harewood GC, McConnell JP, Harrington JJ, Mahoney DW, Ahlquist DA. Detection of occult upper gastrointestinal bleeding: performance in fecal occult blood tests. Mayo Clin Proc. 2002 Jan;77(1):23-28 Blatchford O, et al. A risk score to predict need for treatment for upper gastrointestinal haemorrhage. Lancet 2000. Oct 14;356(9238):1318-21 Blatchford O, Davidson LA, Murray WR, Blatchford M, Pell J. Acute upper gastrointestinal haemorrhage in west of scotland: case ascertainment study. BMJ 1997. Aug 30;315(7107):510-4 Chen IC, Hung MS, Chiu TF, Chen JC, Hsiao CT. Risk scoring systems to predict need for clinical intervention for patients with nonvariceal upper gastrointestinal tract bleeding. Am J Emerg Med. 2007 Sep;25(7):774-9 Laine L, Barkun AN, Saltzman JR, Martel M, Leontiadis GI. ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding. Am J Gastroenterol. 2021 May 1;116(5):899-917 Roberts I, Shakur-STill H, Afolabi A, et al. Effects of High-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet 2020. 395(10241):1927-1936 Aziz M, Haghbin H, Gangwani MK, Weissman S, Patel AR, Randhawa MK, Samikanu LB, Alyousif ZA, Lee-Smith W, Kamal F, Nawras A, Howden CW. Erythromycin improves the quality of esophagogastroduodenoscopy in upper gastrointestinal bleeding: a network meta-analysis. Dig Dis Sci 2023. Apr;68(4):1435-1446 Abraham NS, Barkun AN, Sauer BG, et al. American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period. Am J Gastroenterol 2022;00:1-17 Vigano GL, Mannucci PM, Lattuada A, Harris A, Remuzzi G. Subcutaneous desmopressin (DDAVP) shortens the bleeding time in uremia. Am J Hematol 1989. May;31(1):32-5 Chavez-Tapia NC, Barrientos-Gutierrez T, Tellez-Avila FL, Soares-Weiser K, Uribe M. Antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding. Cochrane Database Syst Rev 2010. Sep 8;2010(9):CD002907 Gao Y, Qian B, Zhang X, Liu H, Han T. Prophylactic antibiotics on patients with cirrhosis and upper gastrointestinal bleeding: A meta-analysis. PLoS One 2022. Dec 22;17(12):e0279496 Steffen R, Knapp J, Hanggi M, Iten M. Use of the REBOA catheter for uncontrollable upper gastrointestinal bleeding with hemorrhagic shock. Anaesthesiologie 2023. May;72(5):332-337 Sato M, Kuriyama A. Countering hemorrhagic shock due to duodenal variceal rupture with resuscitative endovascular balloon occlusion of the aorta. Am J Emerg Med 2023. Feb;64:204.e1-204.e3

Explore the transformative role of Artificial Intelligence (AI) in the fight against COVID-19 and beyond in this episode of "The AI Frontier". We delve into how AI has been instrumental in early virus detection, diagnosis, predicting COVID-19 hotspots, and even accelerating vaccine development. But it's not just about the technological advancements; we also navigate the ethical maze that these AI applications present, from privacy concerns with contact tracing apps to the implications of AI-driven decision making in healthcare. As we look towards a post-COVID world, we discuss the lasting impact of these AI innovations and their potential role in future pandemic preparedness. Join us as we dissect AI's role in pandemic mitigation and the ethical challenges ahead. -------------------------------References used in this episode:1.    Czabanowska K, Kuhlmann E. Public health competences through the lens of the COVID‐19 pandemic: what matters for health workforce preparedness for global health emergencies. Int J Health Plann Mgmt. 2021 May;36(S1):14-9. [Link]2.    Rehman IU, Sobnath D, Nasralla MM, Winnett M, Anwar A, Asif W, et al. Features of Mobile Apps for People with Autism in a Post COVID-19 Scenario: Current Status and Recommendations for Apps Using AI. Diagnostics. 2021 Oct 17;11(10):1923 [Link]3.    Jin C, Chen W, Cao Y, Xu Z, Tan Z, Zhang X, et al. Development and evaluation of an artificial intelligence system for COVID-19 diagnosis. Nat Commun. 2020 Oct 9;11(1). [Link]4.    Kaushik AK, Dhau JS, Gohel H, Mishra YK, Kateb B, Kim N, et al. Electrochemical SARS-CoV-2 Sensing at Point-of-Care and Artificial Intelligence for Intelligent COVID-19 Management. ACS Appl Bio Mater. 2020 Nov 16;3(11):7306-25. [Link]5.    Vinay R, Baumann H, Biller-Andorno N. Ethics of ICU triage during COVID-19. British Medical Bulletin. 2021 Jun 10;138(1):5-15. [Link]6.    Anshari M, Hamdan M, Ahmad N, Ali E, Haidi H. COVID-19, artificial intelligence, ethical challenges and policy implications. AI & Soc. 2023 Apr;38(2):707-20. [Link]Support the Show.Keep AI insights flowing – become a supporter of the show!Click the link for details

Neste episódio falaremos sobre o ASPARTAME Recentemente colocado como "Possível Carcinógeno" pela OMS precisamos nos preocupar? podemos tomar uma Coca? Quais são as evidencias? referencias: Referencias: Debras C, Chazelas E, Srour B, Druesne-Pecollo N, Esseddik Y, Szabo de Edelenyi F, Agaësse C, De Sa A, Lutchia R, Gigandet S, Huybrechts I, Julia C, Kesse-Guyot E, Allès B, Andreeva VA, Galan P, Hercberg S, Deschasaux-Tanguy M, Touvier M. Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study. PLoS Med. 2022 Mar 24;19(3):e1003950. doi: 10.1371/journal.pmed.1003950. Jones GS, Graubard BI, Ramirez Y, Liao LM, Huang WY, Alvarez CS, Yang W, Zhang X, Petrick JL, McGlynn KA. Sweetened beverage consumption and risk of liver cancer by diabetes status: A pooled analysis. Cancer Epidemiol. 2022 Aug;79:102201. doi: 10.1016/j.canep.2022.102201. Epub 2022 Jun 18. PMID: 35728406. Stepien, M. et al. Eur. J. Nutr. 55, 7–20 (2016).

Dr. Ralph W. Moss and son Ben discuss the healing and preventive properties of the readily available, inexpensive and delicious, humble little parsley plant.   Join us for another fascinating journey as we dive 'Beyond the Garnish' into the remarkable world of parsley and its component, Apigenin. This humble herb, often relegated to the sidelines of our plates, holds an impressive secret - the potential to significantly impact the fight against cancer. Program Notes: For more information on cancer-fighting foods and supplements, please visit our website: https://www.themossreport.com 5 Defenders Mushroom Blend https://shop.realmushrooms.com/products/organic-mushroom-blend-capsules?ref=391 “A comprehensive self-help plan for cancer includes medicinal mushrooms. They are indispensable”. – Ralph W. Moss, PhD Olive Oil From the Raw https://www.olivefromtheraw.com/?aff=2 “A study of over 1,000,000 people shows that daily consumption of 2 Tbsp of high quality, extra virgin olive oil that contain polyphenols, results in a 30-40% decrease in cancer incidents.” – Ralph W. Moss, PhD For Dr. Moss' recommended products list, please visit https://www.themossreport.com/recommended-products/ The full scope of research on apigenin and cancer: https://pubmed.ncbi.nlm.nih.gov/?term=apigenin+cancer The Indian review article: Apigenin in cancer prevention and therapy: A systematic review and meta-analysis of animal models https://pubmed.ncbi.nlm.nih.gov/35752426/ The German clinical trial: Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703843/ Recommended parsley intake: Approximately 0.79 tablespoons or 2.37 teaspoons of chopped fresh parsley would provide 10 mg of apigenin. TAKE about one tablespoon OR THE EQUIVALENT AMT. OF DRIED PARSLEY (SEE BELOW) TWICE PER DAY. For 0.69 grams of dried parsley flakes: 0.69 grams / 0.8 grams per teaspoon ≈ 0.86 teaspoons So, approximately one teaspoon 0.86 teaspoons of dried parsley flakes would provide 10 mg of apigenin. OR TAKE THIS TWICE PER DAY. NOTE: PATIENTS IN THE GERMAN STUDY ALSO RECEIVED EGCG (GREEN TEA) AT THE SAME TIME. Based on the average amount of EGCG in one gram of Japanese Sencha green tea leaves (47.3 milligrams), and assuming that you're using one teaspoon (about 2.5 grams) of tea leaves to brew 6 ounces of tea, you can expect to get around 118.25 milligrams of EGCG in your cup of tea. A short bibliography on apigenin and cancer: Shukla S, Gupta S. Apigenin: a promising molecule for cancer prevention. Pharm Res. 2010;27(6):962-978. Salehi B, Venditti A, Sharifi-Rad M, et al. The therapeutic potential of apigenin. Int J Mol Sci. 2019;20(6):1305. Chen AY, Chen YC. A review of the dietary flavonoid, apigenin, on cancer prevention and treatment. Curr Med Chem. 2013;20(19):2570-2581. Fang J, Xia C, Cao Z, Zheng JZ, Reed E, Jiang BH. Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways. FASEB J. 2005;19(3):342-353. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-674. Kim BR, Seo HS, Ku JM, et al. Apigenin inhibits cancer stem cell-like phenotypes in human glioblastoma cells via suppression of c-Met signaling. Phytother Res. 2016;30(5): 800-807. Lu L, Sun T, Chen X, et al. Apigenin inhibits epithelial-mesenchymal transition of human colon cancer cells through the AKT/GSK-3β/Snail signaling pathway. Oncol Rep. 2016;35(1):369-374. Lu Z, Xu S, ER P, et al. Apigenin inhibits the self-renewal capacity of human ovarian cancer SKOV3-derived sphere-forming cells. Mol Med Rep. 2015;11(4): 2850-2856. Wang J, Wu J, Zhang X, et al. Apigenin suppresses the growth of colorectal cancer cells by targeting Twist-mediated epithelial-mesenchymal transition. Mol Med Rep. 2018;17(5): 7305-7310. Yao J, Zhao L, Zhao Q, et al. Apigenin inhibits ovarian cancer stem cell-like properties through the modulation of the Twist1/TGF-β1/Smad3 pathway. Oncol Rep. 2016;36(1): 512-520. For Dr. Moss' Red, Green, and Green Tea Smoothie recipes, visit The Moss Report. These smoothie recipes are just some examples of how you can incorporate natural compounds with potential health benefits into your diet.

Disclaimer: This podcast is not approved for CME credit. Every diabetes treatment plan is different, individual results may vary – nothing you hear on this podcast should be considered medical advice. All claims are supported by clinical evidence referenced in the show notes. For clinical study results, please refer to the Dexcom G7 User Guide. For product-related questions, please refer to the instructions for use. For complete safety information, go to dexcom.com/safety-information.    Fingersticks required for diabetes treatment decisions if symptoms or expectations do not match readings. Dexcom G7 can complete warmup within 30 minutes, whereas other CGM brands require up to an hour or longer. Smart devices are sold separately. For a list of compatible smart devices, visit: dexcom.com/compatibility.  The Dexcom G7 Continuous Glucose Monitoring System (Dexcom G7 System) is a real time, continuous glucose monitoring device indicated for the management of diabetes in persons aged 2 years and older.  Egils Bogdanovics, MD is a paid spokesperson for Dexcom and is a guest on this episode of the podcast. About Hello Dexcom    Dexcom Provider website   Dexcom's partners are working to integrate insulin pumps, insulin pens, and digital health apps with Dexcom G7. Data from collaborator devices and products must be verified by those collaborator devices and products. Users should confirm data and connections with their collaborator devices and products.   A separate Follow app and internet connection are required to follow CGM users' glucose readings and trends. CGM users should always confirm glucose readings on the Dexcom G7 app or receiver before making treatment decisions. Brief Safety Statement BRIEF SAFETY STATEMENT: Failure to use the Dexcom G7 Continuous Glucose Monitoring System (G7) and its components according to the instructions for use provided with your device and available at https://www.dexcom.com/safety-information and to properly consider all indications, contraindications, warnings, precautions, and cautions in those instructions for use may result in you missing a severe hypoglycemia (low blood glucose0 or hyperglycemia (high blood glucose) occurrence and/or making a treatment decision that may result in injury. If your glucose alerts and readings from the G7 do not match symptoms, use a blood glucose meter to make diabetes treatment decisions. Seek medical advice and attention when appropriate, including for any medical emergency. Dexcom Clarity Safety Information The web-based Dexcom Clarity software is intended for use by both home users and healthcare professionals to assist people with diabetes and their healthcare professionals in the review, analysis, and evaluation of historical CGM data to support effective diabetes management. It is intended for use as an accessory to Dexcom CGM devices with data interface capabilities. Caution: The software does not provide any medical advice and should not be used for that purpose. Home users must consult a healthcare professional before making any medical interpretation and therapy adjustments from the information in the software. Caution: Healthcare professionals should use information in the software in conjunction with other clinical information available to them. Caution: Federal (US) law restricts this device to sale by or on the order of a licensed healthcare professional.  Dexcom, Dexcom Follow, Dexcom Clarity, and Dexcom Share are registered trademarks of Dexcom, Inc. in the U.S., and may be registered in other countries. References Dexcom G7 User Guide Seagrove Partners. The Diabetes Forum: 2021 CGM Market Primer. P26 Psavko S, Katz N, Mirchi T, Green CR. Usability and teachability of continuous glucose monitoring devices in older adults and diabetes educators: a task analysis and ease of use survey. JMIR Hum Factors. 2022 Nov 8. doi: 10.2196/42057. Welsh JB, Psavko S, Zhang X, Gao P, Balo AK. Comparisons of Fifth-, Sixth-, and Seventh- Generation Continuous Glucose Monitoring Systems. J Diabetes Sci Technol. 2022 Jun 13:19322968221099879. PMID: 35695305. doi: 10.1177/19322968221099879. Satish K. Garg, MD, et al. Accuracy and Safety of Dexcom G7 Continuous Glucose Monitoring in Adults with Diabetes.Diabetes Technology & Therapeutics.Jun 2022.373 380.http://doi.org/10.1089/dia.2022.0011. Automatically Generated Continuous Glucose Monitoring (CGM) Notifications and Their Association with Glycemic Control Kaushik Shankar, Priscilla Hastedt, Mark Derdzinski, John Welsh, Caleb Barger, Gary Cohen, San Diego, CA, Portland, OR Diabetes 2020;69 (Supplement_1):79-LB Insights from big data (2): Benefits of self-guided retrospective review of continuous glucose monitoring reports. Parker AS, Welsh J, Jimenez A, Walker T. Diabetes Technol Ther. 2018;20(S1):A-27 Denice S Feig, et al. Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial.   

Real-time real talk is intended for healthcare professionals in the US. Disclaimer: This podcast is not approved for CME credit. Every diabetes treatment plan is different, individual results may vary – nothing you hear on this podcast should be considered medical advice. All claims are supported by clinical evidence referenced in the show notes. For clinical study results, please refer to the Dexcom G7 User Guide. For product-related questions, please refer to the instructions for use. For complete safety information, go to dexcom.com/safety-information.    Fingersticks required for diabetes treatment decisions if symptoms or expectations do not match readings. Dexcom G7 can complete warmup within 30 minutes, whereas other CGM brands require up to an hour or longer. Smart devices are sold separately. For a list of compatible smart devices, visit: dexcom.com/compatibility.  The Dexcom G7 Continuous Glucose Monitoring System (Dexcom G7 System) is a real time, continuous glucose monitoring device indicated for the management of diabetes in persons aged 2 years and older.  Egils Bogdanovics, MD is a paid spokesperson for Dexcom and is a guest on this episode of the podcast. About Hello Dexcom    Dexcom Provider website   Dexcom's partners are working to integrate insulin pumps, insulin pens, and digital health apps with Dexcom G7. Data from collaborator devices and products must be verified by those collaborator devices and products. Users should confirm data and connections with their collaborator devices and products.   A separate Follow app and internet connection are required to follow CGM users' glucose readings and trends. CGM users should always confirm glucose readings on the Dexcom G7 app or receiver before making treatment decisions. Brief Safety Statement BRIEF SAFETY STATEMENT: Failure to use the Dexcom G7 Continuous Glucose Monitoring System (G7) and its components according to the instructions for use provided with your device and available at https://www.dexcom.com/safety-information and to properly consider all indications, contraindications, warnings, precautions, and cautions in those instructions for use may result in you missing a severe hypoglycemia (low blood glucose0 or hyperglycemia (high blood glucose) occurrence and/or making a treatment decision that may result in injury. If your glucose alerts and readings from the G7 do not match symptoms, use a blood glucose meter to make diabetes treatment decisions. Seek medical advice and attention when appropriate, including for any medical emergency. Dexcom Clarity Safety Information The web-based Dexcom Clarity software is intended for use by both home users and healthcare professionals to assist people with diabetes and their healthcare professionals in the review, analysis, and evaluation of historical CGM data to support effective diabetes management. It is intended for use as an accessory to Dexcom CGM devices with data interface capabilities. Caution: The software does not provide any medical advice and should not be used for that purpose. Home users must consult a healthcare professional before making any medical interpretation and therapy adjustments from the information in the software. Caution: Healthcare professionals should use information in the software in conjunction with other clinical information available to them. Caution: Federal (US) law restricts this device to sale by or on the order of a licensed healthcare professional.  Dexcom, Dexcom Follow, Dexcom Clarity, and Dexcom Share are registered trademarks of Dexcom, Inc. in the U.S., and may be registered in other countries. References Dexcom G7 User Guide Seagrove Partners. The Diabetes Forum: 2021 CGM Market Primer. P26 Psavko S, Katz N, Mirchi T, Green CR. Usability and teachability of continuous glucose monitoring devices in older adults and diabetes educators: a task analysis and ease of use survey. JMIR Hum Factors. 2022 Nov 8. doi: 10.2196/42057. Welsh JB, Psavko S, Zhang X, Gao P, Balo AK. Comparisons of Fifth-, Sixth-, and Seventh- Generatio

In this episode, Nate, Justin, and Tina sit around the proverbial dinner table to discuss different types of eating patterns or "diets" and why a whole food plant-based diet might deserve a spot at the top of the food chain.Share your reactions and questions with us at  Speak Pipe . We might feature you on a future episode!=== Outline ===1. Introduction2. Chapter 1: Types of Eating Patterns3. Chapter 2: Whole Food Plant-Based Diet4. Chapter 3: Emotional and Psychological Nature of Eating5. Conclusion=== Learning Points ===Patients have different motivations for changing their eating habits: they may wish to lose weight as measured on the scale, change their appearance, or prevent or treat chronic disease. The keto diet, a popular eating diet, can appear to be healthful in the short term: patients are able to lose weight, decrease their blood pressure, and decrease their blood sugar. However, it is not sustainable in the long term and may lead to increased risk of adverse health outcomes. Many scientifically vetted eating patterns, including the DASH diet and Mediterranean diet, share one thing in common: eating a whole food, plant-based diet. Eating a whole food, plant-based diet does not mean the same thing as “vegan;” rather, it emphasizes eating foods in their minimally processed form and minimizing consumption of animal-based foods. === Our Expert(s) ===Dr. Justin Charles is a graduate of the Yale Primary Care Internal Medicine Residency Program.His clinical interests are in Lifestyle Medicine, the use of evidence-based lifestyle interventions to not only prevent, but treat and reverse chronic disease from a root cause perspective. He has received training in Plant-Based Nutrition through the T. Colin Campbell Center for Nutrition Studies and eCornell, as well as Dr. John McDougall's Starch Solution Certification Course.  === Recommended Reading ===Comparison of sociodemographic and nutritional characteristics between self-reported vegetarians, vegans, and meat-eaters from the NurtiNet-Santé Study.Rosenfeld DL. The psychology of vegetarianism: Recent advances and future directions. Appetite 2018; 131:125-38;and Ruby MB. Vegetarianism. A blossoming field of study. Appetite 2012; 58:141-150.Plante CN, Rosenfeld DL, Plante M, Reysen S. The role of social identity motivation in dietary attitudes and behaviors among vegetarians. Appetite 2019; 141 https://doi.org/10.1016/j.appet.2019.05.038Dehghan M, Mente A, Zhang X, et al. Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five contents (PURE): a prospective study.=== About Us ===The Primary Care Pearls (PCP) Podcast is created in collaboration with faculty, residents, and students from the Department of Internal Medicine at the Yale School of Medicine. The project aims to create accessible and informative podcasts about core primary care topics centered around real patient stories.Hosts: Nate WoodProducers: Nate Wood, Helen Cai, August AlloccoLogo and name: Eva ZimmermanTheme music and Editing: Josh OnyangoOther background music: pATCHES, Unicorn Heads, Asher FuleroInstagram: @pcpearlsTwitter: @PCarePearlsListen on most podcast platforms: linktr.ee/pcpearls

High Fat Diet Completely Suppressed by Acidic Activated Charcoal Acidic activated charcoal improved HFD-induced obesity and insulin resistance without any serious adverse effects. These beneficial effects were likely due to modulating lipid absorption and altered FA/BA metabolism. Zhang X, Diao P, Yokoyama H, Inoue Y, Tanabe K, Wang X, Hayashi C, Yokoyama T, Zhang Z, Hu X, Nakajima T, Kimura T, Nakayama J, Nakamuta M, Tanaka N. Acidic Activated Charcoal Prevents Obesity and Insulin Resistance in High-Fat Diet-Fed Mice. Front Nutr. 2022 May 12;9:852767. doi: 10.3389/fnut.2022.852767. PMID: 35634388; PMCID: PMC9134190. #charcoal #diet #metabolism Acidic activated charcoal, red pine, High fat diet, Ultra processed foods, adipose microinflammation, lipid absorption, Akamatsu tree, bile acids, insulin resistance, metabolism, body weight --- Support this podcast: https://anchor.fm/ralph-turchiano/support

Acidic activated charcoal improved HFD-induced obesity and insulin resistance without any serious adverse effects. These beneficial effects were likely due to modulating lipid absorption and altered FA/BA metabolism. Zhang X, Diao P, Yokoyama H, Inoue Y, Tanabe K, Wang X, Hayashi C, Yokoyama T, Zhang Z, Hu X, Nakajima T, Kimura T, Nakayama J, Nakamuta M, Tanaka N. Acidic Activated Charcoal Prevents Obesity and Insulin Resistance in High-Fat Diet-Fed Mice. Front Nutr. 2022 May 12;9:852767. doi: 10.3389/fnut.2022.852767. PMID: 35634388; PMCID: PMC9134190. #charcoal #diet #metabolism Acidic activated charcoal, red pine, High fat diet, Ultra processed foods, adipose microinflammation, lipid absorption, Akamatsu tree, bile acids, insulin resistance, metabolism, body weight --- Support this podcast: https://anchor.fm/ralph-turchiano/support

ترتبط كلمة الإدمان بالعديد من الأمور؛ الألعاب الرقمية، واستخدام الهاتف ومواقع التواصل الاجتماعي، وغيرها. لكن هل سبق وسمعتم عن الإدمان على الحب؟ ترى، ما هي مضاره على الإنسان؟ هذه الحلقة من بحث وكتابة بشر النجار، وتحرير عمر فارس، ومونتاج محمود أبو ندى، وتدقيق تالا مراغه، وتقديم سلام قطناني. في بودكاست «معلوم» تُبسّط سلام قطناني العلوم للإجابة على أسئلة هامّة عن أنفسنا والعالم والكون. بودكاست «معلوم» من إنتاج «صوت». بودكاست «معلوم» من إنتاج «صوت». المصادر: - de Boer A, van Buel EM, Ter Horst GJ. Love is more than just a kiss: A neurobiological perspective on love and affection. Neuroscience. 2012;201:114-124. - Klein MO, Battagello DS, Cardoso AR, Hauser DN, Bittencourt JC, Correa RG. Dopamine: Functions, signaling, and association with neurological diseases. Cell Mol Neurobiol. 2019;39(1):31-59. - Berger M, Gray JA, Roth BL. The expanded biology of serotonin. Annu Rev Med. 2009;60:355-366. - Carter CS. The oxytocin-vasopressin pathway in the context of love and fear. Frontiers in endocrinology. 2017;8:356. - Zou Z, Song H, Zhang Y, Zhang X. Romantic love vs. drug addiction may inspire a new treatment for addiction. Frontiers in psychology. 2016;7:1436. - Earp BD, Wudarczyk OA, Foddy B, Savulescu J. Addicted to love: What is love addiction and when should it be treated? Philosophy, psychiatry, & psychology : PPP. 2017;24(1):77-92. Support the show: https://www.sowt.com/plus

In this third special edition from the 2021 ACIPC Conference, Brett and Martin talk to Distinguished Professor Lidia Morawska about the science of air. Lidia was named in Times magazine as one of the 100 most influential people in the world for helping highlight the airborne spread of COVID-19.  Topics includes in this podcast include the science of aerosolisation from the respiratory tract, activities or source that dictate particle size and terminology around droplet and airbourne transmission. About Lidia: Professor Lidia Morawska is a Distinguished Professor in the School of Earth and Atmospheric Sciences, at the Queensland University of Technology (QUT) in Brisbane. Lidia is an author of over 950 journal papers, book chapters and conference papers and has also been involved at the executive level with a number of relevant national and international professional bodies and has been acting as an advisor to the WHO. Significant papers: 1. Zhou L, Yao M, Zhang X, Hu B, Li X, Chen H, et al. Breath-, air- and surface-borne SARS-CoV-2 in hospitals. J Aerosol Sci. 2021;152:105693. https://www.ncbi.nlm.nih.gov/pubmed/33078030  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557302/pdf/main.pdf 2. Morawska L, Buonanno G. The physics of particle formation and deposition during breathing. Nat Rev Phys. 2021:1-2. https://www.ncbi.nlm.nih.gov/pubmed/33778373 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985916/pdf/42254_2021_Article_307.pdf 3. Cortellessa G, Stabile L, Arpino F, Faleiros DE, van den Bos W, Morawska L, et al. Close proximity risk assessment for SARS-CoV-2 infection. Sci Total Environ. 2021;794:148749.   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242194/pdf/main.pdf 4. Morawska L, Tang JW, Bahnfleth W, Bluyssen PM, Boerstra A, Buonanno G, et al. How can airborne transmission of COVID-19 indoors be minimised? Environ Int. 2020;142:105832. https://www.ncbi.nlm.nih.gov/pubmed/32521345 5. Stockwell RE, Ballard EL, O'Rourke P, Knibbs LD, Morawska L, Bell SC. Indoor hospital air and the impact of ventilation on bioaerosols: a systematic review. J Hosp Infect. 2019;103:175-84.  https://www.ncbi.nlm.nih.gov/pubmed/31279762 6. Morawska L, Milton DK. It Is Time to Address Airborne Transmission of Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2020;71:2311-3. https://www.ncbi.nlm.nih.gov/pubmed/32628269  

In this third special edition from the 2021 ACIPC Conference, Brett and Martin talk to Distinguished Professor Lidia Morawska about the science of air. Lidia was named in Times magazine as one of the 100 most influential people in the world for helping highlight the airborne spread of COVID-19.  Topics includes in this podcast include the science of aerosolisation from the respiratory tract, activities or source that dictate particle size and terminology around droplet and airbourne transmission. About Lidia: Professor Lidia Morawska is a Distinguished Professor in the School of Earth and Atmospheric Sciences, at the Queensland University of Technology (QUT) in Brisbane. Lidia is an author of over 950 journal papers, book chapters and conference papers and has also been involved at the executive level with a number of relevant national and international professional bodies and has been acting as an advisor to the WHO. Significant papers: 1. Zhou L, Yao M, Zhang X, Hu B, Li X, Chen H, et al. Breath-, air- and surface-borne SARS-CoV-2 in hospitals. J Aerosol Sci. 2021;152:105693. https://www.ncbi.nlm.nih.gov/pubmed/33078030  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557302/pdf/main.pdf 2. Morawska L, Buonanno G. The physics of particle formation and deposition during breathing. Nat Rev Phys. 2021:1-2. https://www.ncbi.nlm.nih.gov/pubmed/33778373 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985916/pdf/42254_2021_Article_307.pdf 3. Cortellessa G, Stabile L, Arpino F, Faleiros DE, van den Bos W, Morawska L, et al. Close proximity risk assessment for SARS-CoV-2 infection. Sci Total Environ. 2021;794:148749.   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242194/pdf/main.pdf 4. Morawska L, Tang JW, Bahnfleth W, Bluyssen PM, Boerstra A, Buonanno G, et al. How can airborne transmission of COVID-19 indoors be minimised? Environ Int. 2020;142:105832. https://www.ncbi.nlm.nih.gov/pubmed/32521345 5. Stockwell RE, Ballard EL, O'Rourke P, Knibbs LD, Morawska L, Bell SC. Indoor hospital air and the impact of ventilation on bioaerosols: a systematic review. J Hosp Infect. 2019;103:175-84.  https://www.ncbi.nlm.nih.gov/pubmed/31279762 6. Morawska L, Milton DK. It Is Time to Address Airborne Transmission of Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2020;71:2311-3. https://www.ncbi.nlm.nih.gov/pubmed/32628269  

Jonathan interviews Dr. Kim Noels - Professor, Faculty of Arts - Psychology Department at the University of Alberta. academia.edu Google Scholar Contacts: JonathanShachter@gmail.com, LostInCitations@gmail.com

REFERÊNCIAS1.Pontone G, Scafuri S, Mancini ME, Agalbato C, Guglielmo M, Baggiano A, et al. Role of computed tomography in COVID-19. J Cardiovasc Comput Tomogr. 2021;15(1):27-36.2.Cereser L, Da Re J, Zuiani C, Girometti R. Chest high-resolution computed tomography is associated to short-time progression to severe disease in patients with COVID-19 pneumonia. Clin Imaging. 2021;70:61-6.3.Hochhegger B, Mandelli NS, Stuker G, Meirelles GSP, Zanon M, Mohammed TL, et al. Coronavirus Disease 2019 (COVID-19) Pneumonia Presentations in Chest Computed Tomography: A Pictorial Review. Curr Probl Diagn Radiol. 2021;50(3):436-42.4.Besutti G, Ottone M, Fasano T, Pattacini P, Iotti V, Spaggiari L, et al. The value of computed tomography in assessing the risk of death in COVID-19 patients presenting to the emergency room. Eur Radiol. 2021.5.Mogami R, Lopes AJ, Araujo Filho RC, de Almeida FCS, Messeder A, Koifman ACB, et al. Chest computed tomography in COVID-19 pneumonia: a retrospective study of 155 patients at a university hospital in Rio de Janeiro, Brazil. Radiol Bras. 2021;54(1):1-8.6.Cau R, Falaschi Z, Pasche A, Danna P, Arioli R, Arru CD, et al. CT findings of COVID-19 pneumonia in ICU-patients. J Public Health Res. 2021.7.Kanne JP, Bai H, Bernheim A, Chung M, Haramati LB, Kallmes DF, et al. COVID-19 Imaging: What We Know Now and What Remains Unknown. Radiology. 2021;299(3):E262-E79.8.Pourhoseingholi MA, Jafari R, Jafari NJ, Rahimi-Bashar F, Nourbakhsh M, Vahedian-Azimi A, et al. Predicting 1-year post-COVID-19 mortality based on chest computed tomography scan. J Med Virol. 2021;93(10):5694-6.9.Kato S, Ishiwata Y, Aoki R, Iwasawa T, Hagiwara E, Ogura T, et al. Imaging of COVID-19: An update of current evidences. Diagn Interv Imaging. 2021;102(9):493-500.10.Ozer H, Kilincer A, Uysal E, Yormaz B, Cebeci H, Durmaz MS, et al. Diagnostic performance of Radiological Society of North America structured reporting language for chest computed tomography findings in patients with COVID-19. Jpn J Radiol. 2021;39(9):877-88.11.Ramanan RV, Joshi AR, Venkataramanan A, Nambi SP, Badhe R. Incidental chest computed tomography findings in asymptomatic Covid-19 patients. A multicentre Indian perspective. Indian J Radiol Imaging. 2021;31(Suppl 1):S45-S52.12.Axiaq A, Almohtadi A, Massias SA, Ngemoh D, Harky A. The role of computed tomography scan in the diagnosis of COVID-19 pneumonia. Curr Opin Pulm Med. 2021;27(3):163-8.13.Ishfaq A, Yousaf Farooq SM, Goraya A, Yousaf M, Gilani SA, Kiran A, et al. Role of High Resolution Computed Tomography chest in the diagnosis and evaluation of COVID -19 patients -A systematic review and meta-analysis. Eur J Radiol Open. 2021;8:100350.14.Razek A, Fouda N, Fahmy D, Tanatawy MS, Sultan A, Bilal M, et al. Computed tomography of the chest in patients with COVID-19: what do radiologists want to know? Pol J Radiol. 2021;86:e122-e35.15.Revel MP, Boussouar S, de Margerie-Mellon C, Saab I, Lapotre T, Mompoint D, et al. Study of Thoracic CT in COVID-19: The STOIC Project. Radiology. 2021;301(1):E361-E70.16.Au-Yong I, Higashi Y, Giannotti E, Fogarty A, Morling JR, Grainge M, et al. Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19. Radiology. 2021:210986.17.Little BP. Disease Severity Scoring for COVID-19: A Welcome (Semi)Quantitative Role for Chest Radiography. Radiology. 2021:212212.18.Prokop M, van Everdingen W, van Rees Vellinga T, Quarles van Ufford H, Stoger L, Beenen L, et al. CO-RADS: A Categorical CT Assessment Scheme for Patients Suspected of Having COVID-19-Definition and Evaluation. Radiology. 2020;296(2):E97-E104.19.Ozel M, Aslan A, Arac S. Use of the COVID-19 Reporting and Data System (CO-RADS) classification and chest computed tomography involvement score (CT-IS) in COVID-19 pneumonia. Radiol Med. 2021;126(5):679-87.20.Byrne D, Neill SBO, Muller NL, Muller CIS, Walsh JP, Jalal S, et al. RSNA Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19: Interobserver Agreement Between Chest Radiologists. Can Assoc Radiol J. 2021;72(1):159-66.21.Fonseca E, Loureiro BMC, Strabelli DG, Farias LPG, Garcia JVR, Gama VAA, et al. Evaluation of the RSNA and CORADS classifications for COVID-19 on chest computed tomography in the Brazilian population. Clinics (Sao Paulo). 2021;76:e2476.22.Barisione E, Grillo F, Ball L, Bianchi R, Grosso M, Morbini P, et al. Fibrotic progression and radiologic correlation in matched lung samples from COVID-19 post-mortems. Virchows Arch. 2021;478(3):471-85.23.Kianzad A, Meijboom LJ, Nossent EJ, Roos E, Schurink B, Bonta PI, et al. COVID-19: Histopathological correlates of imaging patterns on chest computed tomography. Respirology. 2021;26(9):869-77.24.Aesif SW, Bribriesco AC, Yadav R, Nugent SL, Zubkus D, Tan CD, et al. Pulmonary Pathology of COVID-19 Following 8 Weeks to 4 Months of Severe Disease: A Report of Three Cases, Including One With Bilateral Lung Transplantation. Am J Clin Pathol. 2021;155(4):506-14.25.De Cobelli F, Palumbo D, Ciceri F, Landoni G, Ruggeri A, Rovere-Querini P, et al. Pulmonary Vascular Thrombosis in COVID-19 Pneumonia. J Cardiothorac Vasc Anesth. 2021.26.Vlachou M, Drebes A, Candilio L, Weeraman D, Mir N, Murch N, et al. Pulmonary thrombosis in Covid-19: before, during and after hospital admission. J Thromb Thrombolysis. 2021;51(4):978-84.27.Caruso D, Guido G, Zerunian M, Polidori T, Lucertini E, Pucciarelli F, et al. Postacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up. Radiology. 2021:210834.28.Han X, Fan Y, Alwalid O, Li N, Jia X, Yuan M, et al. Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia. Radiology. 2021;299(1):E177-E86.29.Solomon JJ, Heyman B, Ko JP, Condos R, Lynch DA. CT of Post-Acute Lung Complications of COVID-19. Radiology. 2021:211396.30.Wells AU, Devaraj A, Desai SR. Interstitial Lung Disease after COVID-19 Infection: A Catalog of Uncertainties. Radiology. 2021;299(1):E216-E8.31.Han X, Fan Y, Alwalid O, Zhang X, Jia X, Zheng Y, et al. Fibrotic Interstitial Lung Abnormalities at 1-year Follow-up CT after Severe COVID-19. Radiology. 2021:210972.32.Lindahl A, Reijula J, Malmberg LP, Aro M, Vasankari T, Makela MJ. Small airway function in Finnish COVID-19 survivors. Respir Res. 2021;22(1):237.33.Small Airways Disease is a Post-Acute Sequelae of SARS-CoV-2 Infection [Internet]. 2021.34.Lopes AJ, Mafort TT, da Cal MS, Monnerat LB, Litrento PF, Ramos I, et al. Impulse Oscillometry Findings and Their Associations With Lung Ultrasound Signs in COVID-19 Survivors. Respir Care. 2021.35.Wells AU, Devaraj A. Residual Lung Disease at 6-month Follow-up CT after COVID-19: Clinical Significance Is a Key Issue. Radiology. 2021:211284.

REFERÊNCIAS1.Pontone G, Scafuri S, Mancini ME, Agalbato C, Guglielmo M, Baggiano A, et al. Role of computed tomography in COVID-19. J Cardiovasc Comput Tomogr. 2021;15(1):27-36.2.Cereser L, Da Re J, Zuiani C, Girometti R. Chest high-resolution computed tomography is associated to short-time progression to severe disease in patients with COVID-19 pneumonia. Clin Imaging. 2021;70:61-6.3.Hochhegger B, Mandelli NS, Stuker G, Meirelles GSP, Zanon M, Mohammed TL, et al. Coronavirus Disease 2019 (COVID-19) Pneumonia Presentations in Chest Computed Tomography: A Pictorial Review. Curr Probl Diagn Radiol. 2021;50(3):436-42.4.Besutti G, Ottone M, Fasano T, Pattacini P, Iotti V, Spaggiari L, et al. The value of computed tomography in assessing the risk of death in COVID-19 patients presenting to the emergency room. Eur Radiol. 2021.5.Mogami R, Lopes AJ, Araujo Filho RC, de Almeida FCS, Messeder A, Koifman ACB, et al. Chest computed tomography in COVID-19 pneumonia: a retrospective study of 155 patients at a university hospital in Rio de Janeiro, Brazil. Radiol Bras. 2021;54(1):1-8.6.Cau R, Falaschi Z, Pasche A, Danna P, Arioli R, Arru CD, et al. CT findings of COVID-19 pneumonia in ICU-patients. J Public Health Res. 2021.7.Kanne JP, Bai H, Bernheim A, Chung M, Haramati LB, Kallmes DF, et al. COVID-19 Imaging: What We Know Now and What Remains Unknown. Radiology. 2021;299(3):E262-E79.8.Pourhoseingholi MA, Jafari R, Jafari NJ, Rahimi-Bashar F, Nourbakhsh M, Vahedian-Azimi A, et al. Predicting 1-year post-COVID-19 mortality based on chest computed tomography scan. J Med Virol. 2021;93(10):5694-6.9.Kato S, Ishiwata Y, Aoki R, Iwasawa T, Hagiwara E, Ogura T, et al. Imaging of COVID-19: An update of current evidences. Diagn Interv Imaging. 2021;102(9):493-500.10.Ozer H, Kilincer A, Uysal E, Yormaz B, Cebeci H, Durmaz MS, et al. Diagnostic performance of Radiological Society of North America structured reporting language for chest computed tomography findings in patients with COVID-19. Jpn J Radiol. 2021;39(9):877-88.11.Ramanan RV, Joshi AR, Venkataramanan A, Nambi SP, Badhe R. Incidental chest computed tomography findings in asymptomatic Covid-19 patients. A multicentre Indian perspective. Indian J Radiol Imaging. 2021;31(Suppl 1):S45-S52.12.Axiaq A, Almohtadi A, Massias SA, Ngemoh D, Harky A. The role of computed tomography scan in the diagnosis of COVID-19 pneumonia. Curr Opin Pulm Med. 2021;27(3):163-8.13.Ishfaq A, Yousaf Farooq SM, Goraya A, Yousaf M, Gilani SA, Kiran A, et al. Role of High Resolution Computed Tomography chest in the diagnosis and evaluation of COVID -19 patients -A systematic review and meta-analysis. Eur J Radiol Open. 2021;8:100350.14.Razek A, Fouda N, Fahmy D, Tanatawy MS, Sultan A, Bilal M, et al. Computed tomography of the chest in patients with COVID-19: what do radiologists want to know? Pol J Radiol. 2021;86:e122-e35.15.Revel MP, Boussouar S, de Margerie-Mellon C, Saab I, Lapotre T, Mompoint D, et al. Study of Thoracic CT in COVID-19: The STOIC Project. Radiology. 2021;301(1):E361-E70.16.Au-Yong I, Higashi Y, Giannotti E, Fogarty A, Morling JR, Grainge M, et al. Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19. Radiology. 2021:210986.17.Little BP. Disease Severity Scoring for COVID-19: A Welcome (Semi)Quantitative Role for Chest Radiography. Radiology. 2021:212212.18.Prokop M, van Everdingen W, van Rees Vellinga T, Quarles van Ufford H, Stoger L, Beenen L, et al. CO-RADS: A Categorical CT Assessment Scheme for Patients Suspected of Having COVID-19-Definition and Evaluation. Radiology. 2020;296(2):E97-E104.19.Ozel M, Aslan A, Arac S. Use of the COVID-19 Reporting and Data System (CO-RADS) classification and chest computed tomography involvement score (CT-IS) in COVID-19 pneumonia. Radiol Med. 2021;126(5):679-87.20.Byrne D, Neill SBO, Muller NL, Muller CIS, Walsh JP, Jalal S, et al. RSNA Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19: Interobserver Agreement Between Chest Radiologists. Can Assoc Radiol J. 2021;72(1):159-66.21.Fonseca E, Loureiro BMC, Strabelli DG, Farias LPG, Garcia JVR, Gama VAA, et al. Evaluation of the RSNA and CORADS classifications for COVID-19 on chest computed tomography in the Brazilian population. Clinics (Sao Paulo). 2021;76:e2476.22.Barisione E, Grillo F, Ball L, Bianchi R, Grosso M, Morbini P, et al. Fibrotic progression and radiologic correlation in matched lung samples from COVID-19 post-mortems. Virchows Arch. 2021;478(3):471-85.23.Kianzad A, Meijboom LJ, Nossent EJ, Roos E, Schurink B, Bonta PI, et al. COVID-19: Histopathological correlates of imaging patterns on chest computed tomography. Respirology. 2021;26(9):869-77.24.Aesif SW, Bribriesco AC, Yadav R, Nugent SL, Zubkus D, Tan CD, et al. Pulmonary Pathology of COVID-19 Following 8 Weeks to 4 Months of Severe Disease: A Report of Three Cases, Including One With Bilateral Lung Transplantation. Am J Clin Pathol. 2021;155(4):506-14.25.De Cobelli F, Palumbo D, Ciceri F, Landoni G, Ruggeri A, Rovere-Querini P, et al. Pulmonary Vascular Thrombosis in COVID-19 Pneumonia. J Cardiothorac Vasc Anesth. 2021.26.Vlachou M, Drebes A, Candilio L, Weeraman D, Mir N, Murch N, et al. Pulmonary thrombosis in Covid-19: before, during and after hospital admission. J Thromb Thrombolysis. 2021;51(4):978-84.27.Caruso D, Guido G, Zerunian M, Polidori T, Lucertini E, Pucciarelli F, et al. Postacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up. Radiology. 2021:210834.28.Han X, Fan Y, Alwalid O, Li N, Jia X, Yuan M, et al. Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia. Radiology. 2021;299(1):E177-E86.29.Solomon JJ, Heyman B, Ko JP, Condos R, Lynch DA. CT of Post-Acute Lung Complications of COVID-19. Radiology. 2021:211396.30.Wells AU, Devaraj A, Desai SR. Interstitial Lung Disease after COVID-19 Infection: A Catalog of Uncertainties. Radiology. 2021;299(1):E216-E8.31.Han X, Fan Y, Alwalid O, Zhang X, Jia X, Zheng Y, et al. Fibrotic Interstitial Lung Abnormalities at 1-year Follow-up CT after Severe COVID-19. Radiology. 2021:210972.32.Lindahl A, Reijula J, Malmberg LP, Aro M, Vasankari T, Makela MJ. Small airway function in Finnish COVID-19 survivors. Respir Res. 2021;22(1):237.33.Small Airways Disease is a Post-Acute Sequelae of SARS-CoV-2 Infection [Internet]. 2021.34.Lopes AJ, Mafort TT, da Cal MS, Monnerat LB, Litrento PF, Ramos I, et al. Impulse Oscillometry Findings and Their Associations With Lung Ultrasound Signs in COVID-19 Survivors. Respir Care. 2021.35.Wells AU, Devaraj A. Residual Lung Disease at 6-month Follow-up CT after COVID-19: Clinical Significance Is a Key Issue. Radiology. 2021:211284.

REFERÊNCIAS1.Pontone G, Scafuri S, Mancini ME, Agalbato C, Guglielmo M, Baggiano A, et al. Role of computed tomography in COVID-19. J Cardiovasc Comput Tomogr. 2021;15(1):27-36.2.Cereser L, Da Re J, Zuiani C, Girometti R. Chest high-resolution computed tomography is associated to short-time progression to severe disease in patients with COVID-19 pneumonia. Clin Imaging. 2021;70:61-6.3.Hochhegger B, Mandelli NS, Stuker G, Meirelles GSP, Zanon M, Mohammed TL, et al. Coronavirus Disease 2019 (COVID-19) Pneumonia Presentations in Chest Computed Tomography: A Pictorial Review. Curr Probl Diagn Radiol. 2021;50(3):436-42.4.Besutti G, Ottone M, Fasano T, Pattacini P, Iotti V, Spaggiari L, et al. The value of computed tomography in assessing the risk of death in COVID-19 patients presenting to the emergency room. Eur Radiol. 2021.5.Mogami R, Lopes AJ, Araujo Filho RC, de Almeida FCS, Messeder A, Koifman ACB, et al. Chest computed tomography in COVID-19 pneumonia: a retrospective study of 155 patients at a university hospital in Rio de Janeiro, Brazil. Radiol Bras. 2021;54(1):1-8.6.Cau R, Falaschi Z, Pasche A, Danna P, Arioli R, Arru CD, et al. CT findings of COVID-19 pneumonia in ICU-patients. J Public Health Res. 2021.7.Kanne JP, Bai H, Bernheim A, Chung M, Haramati LB, Kallmes DF, et al. COVID-19 Imaging: What We Know Now and What Remains Unknown. Radiology. 2021;299(3):E262-E79.8.Pourhoseingholi MA, Jafari R, Jafari NJ, Rahimi-Bashar F, Nourbakhsh M, Vahedian-Azimi A, et al. Predicting 1-year post-COVID-19 mortality based on chest computed tomography scan. J Med Virol. 2021;93(10):5694-6.9.Kato S, Ishiwata Y, Aoki R, Iwasawa T, Hagiwara E, Ogura T, et al. Imaging of COVID-19: An update of current evidences. Diagn Interv Imaging. 2021;102(9):493-500.10.Ozer H, Kilincer A, Uysal E, Yormaz B, Cebeci H, Durmaz MS, et al. Diagnostic performance of Radiological Society of North America structured reporting language for chest computed tomography findings in patients with COVID-19. Jpn J Radiol. 2021;39(9):877-88.11.Ramanan RV, Joshi AR, Venkataramanan A, Nambi SP, Badhe R. Incidental chest computed tomography findings in asymptomatic Covid-19 patients. A multicentre Indian perspective. Indian J Radiol Imaging. 2021;31(Suppl 1):S45-S52.12.Axiaq A, Almohtadi A, Massias SA, Ngemoh D, Harky A. The role of computed tomography scan in the diagnosis of COVID-19 pneumonia. Curr Opin Pulm Med. 2021;27(3):163-8.13.Ishfaq A, Yousaf Farooq SM, Goraya A, Yousaf M, Gilani SA, Kiran A, et al. Role of High Resolution Computed Tomography chest in the diagnosis and evaluation of COVID -19 patients -A systematic review and meta-analysis. Eur J Radiol Open. 2021;8:100350.14.Razek A, Fouda N, Fahmy D, Tanatawy MS, Sultan A, Bilal M, et al. Computed tomography of the chest in patients with COVID-19: what do radiologists want to know? Pol J Radiol. 2021;86:e122-e35.15.Revel MP, Boussouar S, de Margerie-Mellon C, Saab I, Lapotre T, Mompoint D, et al. Study of Thoracic CT in COVID-19: The STOIC Project. Radiology. 2021;301(1):E361-E70.16.Au-Yong I, Higashi Y, Giannotti E, Fogarty A, Morling JR, Grainge M, et al. Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19. Radiology. 2021:210986.17.Little BP. Disease Severity Scoring for COVID-19: A Welcome (Semi)Quantitative Role for Chest Radiography. Radiology. 2021:212212.18.Prokop M, van Everdingen W, van Rees Vellinga T, Quarles van Ufford H, Stoger L, Beenen L, et al. CO-RADS: A Categorical CT Assessment Scheme for Patients Suspected of Having COVID-19-Definition and Evaluation. Radiology. 2020;296(2):E97-E104.19.Ozel M, Aslan A, Arac S. Use of the COVID-19 Reporting and Data System (CO-RADS) classification and chest computed tomography involvement score (CT-IS) in COVID-19 pneumonia. Radiol Med. 2021;126(5):679-87.20.Byrne D, Neill SBO, Muller NL, Muller CIS, Walsh JP, Jalal S, et al. RSNA Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19: Interobserver Agreement Between Chest Radiologists. Can Assoc Radiol J. 2021;72(1):159-66.21.Fonseca E, Loureiro BMC, Strabelli DG, Farias LPG, Garcia JVR, Gama VAA, et al. Evaluation of the RSNA and CORADS classifications for COVID-19 on chest computed tomography in the Brazilian population. Clinics (Sao Paulo). 2021;76:e2476.22.Barisione E, Grillo F, Ball L, Bianchi R, Grosso M, Morbini P, et al. Fibrotic progression and radiologic correlation in matched lung samples from COVID-19 post-mortems. Virchows Arch. 2021;478(3):471-85.23.Kianzad A, Meijboom LJ, Nossent EJ, Roos E, Schurink B, Bonta PI, et al. COVID-19: Histopathological correlates of imaging patterns on chest computed tomography. Respirology. 2021;26(9):869-77.24.Aesif SW, Bribriesco AC, Yadav R, Nugent SL, Zubkus D, Tan CD, et al. Pulmonary Pathology of COVID-19 Following 8 Weeks to 4 Months of Severe Disease: A Report of Three Cases, Including One With Bilateral Lung Transplantation. Am J Clin Pathol. 2021;155(4):506-14.25.De Cobelli F, Palumbo D, Ciceri F, Landoni G, Ruggeri A, Rovere-Querini P, et al. Pulmonary Vascular Thrombosis in COVID-19 Pneumonia. J Cardiothorac Vasc Anesth. 2021.26.Vlachou M, Drebes A, Candilio L, Weeraman D, Mir N, Murch N, et al. Pulmonary thrombosis in Covid-19: before, during and after hospital admission. J Thromb Thrombolysis. 2021;51(4):978-84.27.Caruso D, Guido G, Zerunian M, Polidori T, Lucertini E, Pucciarelli F, et al. Postacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up. Radiology. 2021:210834.28.Han X, Fan Y, Alwalid O, Li N, Jia X, Yuan M, et al. Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia. Radiology. 2021;299(1):E177-E86.29.Solomon JJ, Heyman B, Ko JP, Condos R, Lynch DA. CT of Post-Acute Lung Complications of COVID-19. Radiology. 2021:211396.30.Wells AU, Devaraj A, Desai SR. Interstitial Lung Disease after COVID-19 Infection: A Catalog of Uncertainties. Radiology. 2021;299(1):E216-E8.31.Han X, Fan Y, Alwalid O, Zhang X, Jia X, Zheng Y, et al. Fibrotic Interstitial Lung Abnormalities at 1-year Follow-up CT after Severe COVID-19. Radiology. 2021:210972.32.Lindahl A, Reijula J, Malmberg LP, Aro M, Vasankari T, Makela MJ. Small airway function in Finnish COVID-19 survivors. Respir Res. 2021;22(1):237.33.Small Airways Disease is a Post-Acute Sequelae of SARS-CoV-2 Infection [Internet]. 2021.34.Lopes AJ, Mafort TT, da Cal MS, Monnerat LB, Litrento PF, Ramos I, et al. Impulse Oscillometry Findings and Their Associations With Lung Ultrasound Signs in COVID-19 Survivors. Respir Care. 2021.35.Wells AU, Devaraj A. Residual Lung Disease at 6-month Follow-up CT after COVID-19: Clinical Significance Is a Key Issue. Radiology. 2021:211284.

REFERÊNCIAS1.Pontone G, Scafuri S, Mancini ME, Agalbato C, Guglielmo M, Baggiano A, et al. Role of computed tomography in COVID-19. J Cardiovasc Comput Tomogr. 2021;15(1):27-36.2.Cereser L, Da Re J, Zuiani C, Girometti R. Chest high-resolution computed tomography is associated to short-time progression to severe disease in patients with COVID-19 pneumonia. Clin Imaging. 2021;70:61-6.3.Hochhegger B, Mandelli NS, Stuker G, Meirelles GSP, Zanon M, Mohammed TL, et al. Coronavirus Disease 2019 (COVID-19) Pneumonia Presentations in Chest Computed Tomography: A Pictorial Review. Curr Probl Diagn Radiol. 2021;50(3):436-42.4.Besutti G, Ottone M, Fasano T, Pattacini P, Iotti V, Spaggiari L, et al. The value of computed tomography in assessing the risk of death in COVID-19 patients presenting to the emergency room. Eur Radiol. 2021.5.Mogami R, Lopes AJ, Araujo Filho RC, de Almeida FCS, Messeder A, Koifman ACB, et al. Chest computed tomography in COVID-19 pneumonia: a retrospective study of 155 patients at a university hospital in Rio de Janeiro, Brazil. Radiol Bras. 2021;54(1):1-8.6.Cau R, Falaschi Z, Pasche A, Danna P, Arioli R, Arru CD, et al. CT findings of COVID-19 pneumonia in ICU-patients. J Public Health Res. 2021.7.Kanne JP, Bai H, Bernheim A, Chung M, Haramati LB, Kallmes DF, et al. COVID-19 Imaging: What We Know Now and What Remains Unknown. Radiology. 2021;299(3):E262-E79.8.Pourhoseingholi MA, Jafari R, Jafari NJ, Rahimi-Bashar F, Nourbakhsh M, Vahedian-Azimi A, et al. Predicting 1-year post-COVID-19 mortality based on chest computed tomography scan. J Med Virol. 2021;93(10):5694-6.9.Kato S, Ishiwata Y, Aoki R, Iwasawa T, Hagiwara E, Ogura T, et al. Imaging of COVID-19: An update of current evidences. Diagn Interv Imaging. 2021;102(9):493-500.10.Ozer H, Kilincer A, Uysal E, Yormaz B, Cebeci H, Durmaz MS, et al. Diagnostic performance of Radiological Society of North America structured reporting language for chest computed tomography findings in patients with COVID-19. Jpn J Radiol. 2021;39(9):877-88.11.Ramanan RV, Joshi AR, Venkataramanan A, Nambi SP, Badhe R. Incidental chest computed tomography findings in asymptomatic Covid-19 patients. A multicentre Indian perspective. Indian J Radiol Imaging. 2021;31(Suppl 1):S45-S52.12.Axiaq A, Almohtadi A, Massias SA, Ngemoh D, Harky A. The role of computed tomography scan in the diagnosis of COVID-19 pneumonia. Curr Opin Pulm Med. 2021;27(3):163-8.13.Ishfaq A, Yousaf Farooq SM, Goraya A, Yousaf M, Gilani SA, Kiran A, et al. Role of High Resolution Computed Tomography chest in the diagnosis and evaluation of COVID -19 patients -A systematic review and meta-analysis. Eur J Radiol Open. 2021;8:100350.14.Razek A, Fouda N, Fahmy D, Tanatawy MS, Sultan A, Bilal M, et al. Computed tomography of the chest in patients with COVID-19: what do radiologists want to know? Pol J Radiol. 2021;86:e122-e35.15.Revel MP, Boussouar S, de Margerie-Mellon C, Saab I, Lapotre T, Mompoint D, et al. Study of Thoracic CT in COVID-19: The STOIC Project. Radiology. 2021;301(1):E361-E70.16.Au-Yong I, Higashi Y, Giannotti E, Fogarty A, Morling JR, Grainge M, et al. Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19. Radiology. 2021:210986.17.Little BP. Disease Severity Scoring for COVID-19: A Welcome (Semi)Quantitative Role for Chest Radiography. Radiology. 2021:212212.18.Prokop M, van Everdingen W, van Rees Vellinga T, Quarles van Ufford H, Stoger L, Beenen L, et al. CO-RADS: A Categorical CT Assessment Scheme for Patients Suspected of Having COVID-19-Definition and Evaluation. Radiology. 2020;296(2):E97-E104.19.Ozel M, Aslan A, Arac S. Use of the COVID-19 Reporting and Data System (CO-RADS) classification and chest computed tomography involvement score (CT-IS) in COVID-19 pneumonia. Radiol Med. 2021;126(5):679-87.20.Byrne D, Neill SBO, Muller NL, Muller CIS, Walsh JP, Jalal S, et al. RSNA Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19: Interobserver Agreement Between Chest Radiologists. Can Assoc Radiol J. 2021;72(1):159-66.21.Fonseca E, Loureiro BMC, Strabelli DG, Farias LPG, Garcia JVR, Gama VAA, et al. Evaluation of the RSNA and CORADS classifications for COVID-19 on chest computed tomography in the Brazilian population. Clinics (Sao Paulo). 2021;76:e2476.22.Barisione E, Grillo F, Ball L, Bianchi R, Grosso M, Morbini P, et al. Fibrotic progression and radiologic correlation in matched lung samples from COVID-19 post-mortems. Virchows Arch. 2021;478(3):471-85.23.Kianzad A, Meijboom LJ, Nossent EJ, Roos E, Schurink B, Bonta PI, et al. COVID-19: Histopathological correlates of imaging patterns on chest computed tomography. Respirology. 2021;26(9):869-77.24.Aesif SW, Bribriesco AC, Yadav R, Nugent SL, Zubkus D, Tan CD, et al. Pulmonary Pathology of COVID-19 Following 8 Weeks to 4 Months of Severe Disease: A Report of Three Cases, Including One With Bilateral Lung Transplantation. Am J Clin Pathol. 2021;155(4):506-14.25.De Cobelli F, Palumbo D, Ciceri F, Landoni G, Ruggeri A, Rovere-Querini P, et al. Pulmonary Vascular Thrombosis in COVID-19 Pneumonia. J Cardiothorac Vasc Anesth. 2021.26.Vlachou M, Drebes A, Candilio L, Weeraman D, Mir N, Murch N, et al. Pulmonary thrombosis in Covid-19: before, during and after hospital admission. J Thromb Thrombolysis. 2021;51(4):978-84.27.Caruso D, Guido G, Zerunian M, Polidori T, Lucertini E, Pucciarelli F, et al. Postacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up. Radiology. 2021:210834.28.Han X, Fan Y, Alwalid O, Li N, Jia X, Yuan M, et al. Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia. Radiology. 2021;299(1):E177-E86.29.Solomon JJ, Heyman B, Ko JP, Condos R, Lynch DA. CT of Post-Acute Lung Complications of COVID-19. Radiology. 2021:211396.30.Wells AU, Devaraj A, Desai SR. Interstitial Lung Disease after COVID-19 Infection: A Catalog of Uncertainties. Radiology. 2021;299(1):E216-E8.31.Han X, Fan Y, Alwalid O, Zhang X, Jia X, Zheng Y, et al. Fibrotic Interstitial Lung Abnormalities at 1-year Follow-up CT after Severe COVID-19. Radiology. 2021:210972.32.Lindahl A, Reijula J, Malmberg LP, Aro M, Vasankari T, Makela MJ. Small airway function in Finnish COVID-19 survivors. Respir Res. 2021;22(1):237.33.Small Airways Disease is a Post-Acute Sequelae of SARS-CoV-2 Infection [Internet]. 2021.34.Lopes AJ, Mafort TT, da Cal MS, Monnerat LB, Litrento PF, Ramos I, et al. Impulse Oscillometry Findings and Their Associations With Lung Ultrasound Signs in COVID-19 Survivors. Respir Care. 2021.35.Wells AU, Devaraj A. Residual Lung Disease at 6-month Follow-up CT after COVID-19: Clinical Significance Is a Key Issue. Radiology. 2021:211284.

REFERÊNCIAS1.Pontone G, Scafuri S, Mancini ME, Agalbato C, Guglielmo M, Baggiano A, et al. Role of computed tomography in COVID-19. J Cardiovasc Comput Tomogr. 2021;15(1):27-36.2.Cereser L, Da Re J, Zuiani C, Girometti R. Chest high-resolution computed tomography is associated to short-time progression to severe disease in patients with COVID-19 pneumonia. Clin Imaging. 2021;70:61-6.3.Hochhegger B, Mandelli NS, Stuker G, Meirelles GSP, Zanon M, Mohammed TL, et al. Coronavirus Disease 2019 (COVID-19) Pneumonia Presentations in Chest Computed Tomography: A Pictorial Review. Curr Probl Diagn Radiol. 2021;50(3):436-42.4.Besutti G, Ottone M, Fasano T, Pattacini P, Iotti V, Spaggiari L, et al. The value of computed tomography in assessing the risk of death in COVID-19 patients presenting to the emergency room. Eur Radiol. 2021.5.Mogami R, Lopes AJ, Araujo Filho RC, de Almeida FCS, Messeder A, Koifman ACB, et al. Chest computed tomography in COVID-19 pneumonia: a retrospective study of 155 patients at a university hospital in Rio de Janeiro, Brazil. Radiol Bras. 2021;54(1):1-8.6.Cau R, Falaschi Z, Pasche A, Danna P, Arioli R, Arru CD, et al. CT findings of COVID-19 pneumonia in ICU-patients. J Public Health Res. 2021.7.Kanne JP, Bai H, Bernheim A, Chung M, Haramati LB, Kallmes DF, et al. COVID-19 Imaging: What We Know Now and What Remains Unknown. Radiology. 2021;299(3):E262-E79.8.Pourhoseingholi MA, Jafari R, Jafari NJ, Rahimi-Bashar F, Nourbakhsh M, Vahedian-Azimi A, et al. Predicting 1-year post-COVID-19 mortality based on chest computed tomography scan. J Med Virol. 2021;93(10):5694-6.9.Kato S, Ishiwata Y, Aoki R, Iwasawa T, Hagiwara E, Ogura T, et al. Imaging of COVID-19: An update of current evidences. Diagn Interv Imaging. 2021;102(9):493-500.10.Ozer H, Kilincer A, Uysal E, Yormaz B, Cebeci H, Durmaz MS, et al. Diagnostic performance of Radiological Society of North America structured reporting language for chest computed tomography findings in patients with COVID-19. Jpn J Radiol. 2021;39(9):877-88.11.Ramanan RV, Joshi AR, Venkataramanan A, Nambi SP, Badhe R. Incidental chest computed tomography findings in asymptomatic Covid-19 patients. A multicentre Indian perspective. Indian J Radiol Imaging. 2021;31(Suppl 1):S45-S52.12.Axiaq A, Almohtadi A, Massias SA, Ngemoh D, Harky A. The role of computed tomography scan in the diagnosis of COVID-19 pneumonia. Curr Opin Pulm Med. 2021;27(3):163-8.13.Ishfaq A, Yousaf Farooq SM, Goraya A, Yousaf M, Gilani SA, Kiran A, et al. Role of High Resolution Computed Tomography chest in the diagnosis and evaluation of COVID -19 patients -A systematic review and meta-analysis. Eur J Radiol Open. 2021;8:100350.14.Razek A, Fouda N, Fahmy D, Tanatawy MS, Sultan A, Bilal M, et al. Computed tomography of the chest in patients with COVID-19: what do radiologists want to know? Pol J Radiol. 2021;86:e122-e35.15.Revel MP, Boussouar S, de Margerie-Mellon C, Saab I, Lapotre T, Mompoint D, et al. Study of Thoracic CT in COVID-19: The STOIC Project. Radiology. 2021;301(1):E361-E70.16.Au-Yong I, Higashi Y, Giannotti E, Fogarty A, Morling JR, Grainge M, et al. Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19. Radiology. 2021:210986.17.Little BP. Disease Severity Scoring for COVID-19: A Welcome (Semi)Quantitative Role for Chest Radiography. Radiology. 2021:212212.18.Prokop M, van Everdingen W, van Rees Vellinga T, Quarles van Ufford H, Stoger L, Beenen L, et al. CO-RADS: A Categorical CT Assessment Scheme for Patients Suspected of Having COVID-19-Definition and Evaluation. Radiology. 2020;296(2):E97-E104.19.Ozel M, Aslan A, Arac S. Use of the COVID-19 Reporting and Data System (CO-RADS) classification and chest computed tomography involvement score (CT-IS) in COVID-19 pneumonia. Radiol Med. 2021;126(5):679-87.20.Byrne D, Neill SBO, Muller NL, Muller CIS, Walsh JP, Jalal S, et al. RSNA Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19: Interobserver Agreement Between Chest Radiologists. Can Assoc Radiol J. 2021;72(1):159-66.21.Fonseca E, Loureiro BMC, Strabelli DG, Farias LPG, Garcia JVR, Gama VAA, et al. Evaluation of the RSNA and CORADS classifications for COVID-19 on chest computed tomography in the Brazilian population. Clinics (Sao Paulo). 2021;76:e2476.22.Barisione E, Grillo F, Ball L, Bianchi R, Grosso M, Morbini P, et al. Fibrotic progression and radiologic correlation in matched lung samples from COVID-19 post-mortems. Virchows Arch. 2021;478(3):471-85.23.Kianzad A, Meijboom LJ, Nossent EJ, Roos E, Schurink B, Bonta PI, et al. COVID-19: Histopathological correlates of imaging patterns on chest computed tomography. Respirology. 2021;26(9):869-77.24.Aesif SW, Bribriesco AC, Yadav R, Nugent SL, Zubkus D, Tan CD, et al. Pulmonary Pathology of COVID-19 Following 8 Weeks to 4 Months of Severe Disease: A Report of Three Cases, Including One With Bilateral Lung Transplantation. Am J Clin Pathol. 2021;155(4):506-14.25.De Cobelli F, Palumbo D, Ciceri F, Landoni G, Ruggeri A, Rovere-Querini P, et al. Pulmonary Vascular Thrombosis in COVID-19 Pneumonia. J Cardiothorac Vasc Anesth. 2021.26.Vlachou M, Drebes A, Candilio L, Weeraman D, Mir N, Murch N, et al. Pulmonary thrombosis in Covid-19: before, during and after hospital admission. J Thromb Thrombolysis. 2021;51(4):978-84.27.Caruso D, Guido G, Zerunian M, Polidori T, Lucertini E, Pucciarelli F, et al. Postacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up. Radiology. 2021:210834.28.Han X, Fan Y, Alwalid O, Li N, Jia X, Yuan M, et al. Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia. Radiology. 2021;299(1):E177-E86.29.Solomon JJ, Heyman B, Ko JP, Condos R, Lynch DA. CT of Post-Acute Lung Complications of COVID-19. Radiology. 2021:211396.30.Wells AU, Devaraj A, Desai SR. Interstitial Lung Disease after COVID-19 Infection: A Catalog of Uncertainties. Radiology. 2021;299(1):E216-E8.31.Han X, Fan Y, Alwalid O, Zhang X, Jia X, Zheng Y, et al. Fibrotic Interstitial Lung Abnormalities at 1-year Follow-up CT after Severe COVID-19. Radiology. 2021:210972.32.Lindahl A, Reijula J, Malmberg LP, Aro M, Vasankari T, Makela MJ. Small airway function in Finnish COVID-19 survivors. Respir Res. 2021;22(1):237.33.Small Airways Disease is a Post-Acute Sequelae of SARS-CoV-2 Infection [Internet]. 2021.34.Lopes AJ, Mafort TT, da Cal MS, Monnerat LB, Litrento PF, Ramos I, et al. Impulse Oscillometry Findings and Their Associations With Lung Ultrasound Signs in COVID-19 Survivors. Respir Care. 2021.35.Wells AU, Devaraj A. Residual Lung Disease at 6-month Follow-up CT after COVID-19: Clinical Significance Is a Key Issue. Radiology. 2021:211284.

Czy naprawdę potrzebujemy specjalnych diet detox, żeby "oczyścić" organizm z toksyn? Zgodzę się z tym, że dieta detox może być odciążeniem dla wątroby i nerek, zwłaszcza jeżeli na co dzień żyjemy w sposób typowo zachodni, tj. jemy mało warzyw i owoców, dużo produktów pochodzenia zwierzęcego, nie mamy aktywności fizycznej i spędzamy całe dnie przed komputerem. Jednakże, czy jest to dobra strategia w dłuższej perspektywie czasu? W dzisiejszym odcinku wyjaśniam, o co trzeba zadbać w codziennej diecie i stylu życia, żeby struktury odpowiedzialne za usuwanie szkodliwych substancji pracowały sprawnie i wydajnie. Dzięki temu, żadna dieta detoks nie będzie Ci więcej potrzebna i zdecydowanie zaoszczędzisz na butelkach soków.Jeżeli masz pytania do tego odcinka napisz do mnie na malgorzata@pielichowska.pl Odwiedź moją stronę: https://pielichowska.pl/blogZapisz się do newslettera: https://pielichowska.pl/podcast (na dole strony)Zostań moim Patronem: https://patronite.pl/pielichowska Odwiedź mojego Facebooka: https://www.facebook.com/pielichowska.dietetyk Odwiedź mojego Instagrama: https://www.instagram.com/gosia.pielichowska/ Literatura:Li H, Wang X, Ye M, Zhang S, Zhang Q, Meng G, Liu L, Wu H, Gu Y, Wang Y, Zhang T, Sun S, Wang X, Zhou M, Jia Q, Song K, Wang Y, Niu K. Does a high intake of green leafy vegetables protect from NAFLD? Evidence from a large population study. Nutr Metab Cardiovasc Dis. 2021 Feb 2:S0939-4753(21)00028-4. doi: 10.1016/j.numecd.2021.01.009.Yu D, Shu XO, Xiang YB, Li H, Yang G, Gao YT, Zheng W, Zhang X. Higher dietary choline intake is associated with lower risk of nonalcoholic fatty liver in normal-weight Chinese women. J Nutr. 2014 Dec;144(12):2034-40. doi: 10.3945/jn.114.197533.Saran, A. R., Dave, S., & Zarrinpar, A. (2020). Circadian Rhythms in the Pathogenesis and Treatment of Fatty Liver Disease. Gastroenterology, 158(7), 1948–1966.e1. https://doi.org/10.1053/j.gastro.2020.01.050Gould RL, Pazdro R. Impact of Supplementary Amino Acids, Micronutrients, and Overall Diet on Glutathione Homeostasis. Nutrients. 2019 May 11;11(5):1056. doi: 10.3390/nu11051056.Minich DM, Brown BI. A Review of Dietary (Phyto)Nutrients for Glutathione Support. Nutrients. 2019 Sep 3;11(9):2073. doi: 10.3390/nu11092073.Kieffer DA, Martin RJ, Adams SH. Impact of Dietary Fibers on Nutrient Management and Detoxification Organs: Gut, Liver, and Kidneys. Adv Nutr. 2016 Nov 15;7(6):1111-1121. doi: 10.3945/an.116.013219.

Reference List: 1. Aune D, Chan DS, Vieira AR, et al. Dietary compared with blood concentrations of carotenoids and breast cancer risk: a systematic review and meta-analysis of prospective studies. Am J Clin Nutr 2012, 96:356-373. doi: 10.3945/ajcn.112.034165 2. Thomson CA, Rock CL, Thompson PA, et al. Vegetable intake is associated with reduced breast cancer recurrence in tamoxifen users: a secondary analysis from the Women's Healthy Eating and Living Study. Breast Cancer Research and Treatment 2011, 125:519-527. doi: 10.1007/s10549-010-1014-9 3. Lee SA, Fowke JH, Lu W, et al. Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk. Am J Clin Nutr 2008, 87:753-760. 4. Seow A, Yuan JM, Sun CL, et al. Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. Carcinogenesis 2002, 23:2055-2061. doi: 10.1093/carcin/23.12.2055 5. Zhang X, Shu XO, Xiang YB, et al. Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality. Am J Clin Nutr 2011, 94:240-246. doi: 10.3945/ajcn.110.009340 6. Darmadi-Blackberry I, Wahlqvist ML, Kouris-Blazos A, et al. Legumes: the most important dietary predictor of survival in older people of different ethnicities. Asia Pac J Clin Nutr 2004, 13:217-220. doi: 7. Piccolo E, Vignati S, Maffucci T, et al. Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway. Oncogene 2004, 23:1754-1765. doi: 10.1038/sj.onc.1207296 8. Galeone C, Pelucchi C, Levi F, et al. Onion and garlic use and human cancer. Am J Clin Nutr 2006, 84:1027-1032. doi: 10.1093/ajcn/84.5.1027 9. Thompson LU, Chen JM, Li T, et al. Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. Clin Cancer Res 2005, 11:3828-3835. doi: 10.1158/1078-0432.CCR-04-2326 10. McCann SE, Thompson LU, Nie J, et al. Dietary lignan intakes in relation to survival among women with breast cancer: the Western New York Exposures and Breast Cancer (WEB) Study. Breast Cancer Res Treat 2010, 122:229-235. doi: 10.1007/s10549-009-0681-x 11. Anand P, Sundaram C, Jhurani S, et al. Curcumin and cancer: an "old-age" disease with an "age-old" solution. Cancer Lett 2008, 267:133-164. doi: 10.1016/j.canlet.2008.03.025 12. Giovannucci E, Rimm EB, Liu Y, et al. A prospective study of tomato products, lycopene, and prostate cancer risk. J Natl Cancer Inst 2002, 94:391-398. doi: 10.1093/jnci/94.5.391 13. Grainger EM, Schwartz SJ, Wang S, et al. A combination of tomato and soy products for men with recurring prostate cancer and rising prostate specific antigen. Nutr Cancer 2008, 60:145-154. doi: 10.1080/01635580701621338

In this episode of Science & Chill, I talk with Dr. Karyn Esser, the associate program director at the Institute of Myology at the University of Florida.  Dr. Esser is an expert in the area of biological rhythms, also known as circadian rhythms. In particular, her group focuses on how circadian rhythms function in skeletal muscle and respond to things like exercise, feeding, and light.  In this episode, we talk about why humans (and plants and animals) have circadian rhythms in the first place, the importance of sleep and exercise for maintaining circadian rhythms, and much more. Dr. Esser also answers some bonus questions at the end!  I hope you enjoy this episode. If you do, please leave a 5-star rating, share it with friends and family, or write a review! If you have any questions or comments about the podcast, send them to scienceandchillpodcast@gmail.com.   Links: Great video on Dr. Esser and Circadian Rhythms: https://youtu.be/QZWllk38iSE Dr. Esser's bio: https://physiology.med.ufl.edu/faculty/karyn-esser-phd/ Dr. Esser's publications: https://pubmed.ncbi.nlm.nih.gov/?cmd=search&term=esser+ka Follow Dr. Esser on Twitter: @kaesser  Follow Science & Chill on Twitter: @ScienceChill Subscribe on iTunes    SHOW NOTES:   Check out this great video on Dr. Karyn Esser from the University of Florida https://youtu.be/QZWllk38iSE Dr. Karyn Esser's scientific publications: https://pubmed.ncbi.nlm.nih.gov/?cmd=search&term=esser+ka   Relevant publications:   Harfmann BD, Schroder EA, Esser KA. Circadian rhythms, the molecular clock, and skeletal muscle. J Biol Rhythms. 2015;30(2):84–94. Riley LA, Esser KA. The Role of the Molecular Clock in Skeletal Muscle and What It Is Teaching Us About Muscle-Bone Crosstalk. Curr Osteoporos Rep. 2017;15(3):222–230. Wolff CA, Esser KA. Exercise Timing and Circadian Rhythms. Curr Opin Physiol. 2019;10:64–69. Hodge BA, Zhang X, Gutierrez-Monreal MA, et al. MYOD1 functions as a clock amplifier as well as a critical co-factor for downstream circadian gene expression in muscle. Elife. 2019. In this episode we talk about:    7:30: The utility of Twitter for scientists: how Dr. Esser uses Twitter to solve problems in her lab, and why she encourages her students and trainees to use Twitter for academic reasons. You can follow Dr. Esser on Twitter here: @kaesser  13:17: Dr. Essers introduction into science. She didn't always “want” to be a scientist -- instead starting as a math major and was interested in band and athletics (she wanted to be a conductor at a young age).  Her 7th grade laboratory class taught her a lot about the fundamentals of science  She started as a chemistry major at Wake Forest, and in one class was able to take a trip to the Galapagos Islands. This trip shaped a lot of her thinking about evolutionary approaches to science. 19:00: Our mutual experience working in cardiac rehabilitation  22:30: Working with an exercise program at the University of Nevada Las Vegas (UNLV) 30:30: 2017 Nobel Prize in Physiology and/or Medicine. The prize was awarded to Jeffrey C. Hall, Michael Rosbash, and Michael W. Young “for their discoveries of molecular mechanisms controlling the circadian rhythm.”  Nobel Society press release:  https://www.nobelprize.org/prizes/medicine/2017/press-release/ 36:00: The SCN is no longer considered the “master clock” controlling our circadian rhythms.   We have clocks throughout the body that dictate their own rhythm 38:15: What time of day and when we are exposed to cues like exercise, light, and food play a crucial role in “setting the clock” for our cells We can “misalign” clocks by sending cues at the wrong times of day or traveling time zones “Social jetlag” 40:00: Circadian clocks in skeletal muscles and how they respond to exercise Clocks are sensitive to temperature 42:00: Chronic diseases and aging affect  our circadian clocks 44:20: Consequences of circadian misalignment Shift workers have higher risks for cardiovascular disease and metabolic problems Increased insulin resistance, blood pressure 48:00  Time-restricted feeding 50:00: Circadian timing of drugs and medicine 50:45: How circadian rhythms apply to exercise and performance 51:00: Therapeutic uses for circadian rhythms Timing exercise to improve sleep outcomes and metabolic health Small molecules with clocks effects that might hold the potential for drug development 53:20: Why exercise is a good thing...REGARDLESS of when you do it We recently had a Twitter conversation about this issue on a recent paper about how exercise timing might influence insulin sensitivity 55:00: Some studies proposing to study the effects of circadian rhythms on training adaptations might not actually be studying circadian rhythms PAPER: Effect of time-of-day specific strength training on muscular hypertrophy in men CONCLUSIONS: “The magnitude of muscular hypertrophy did not statistically differ between the morning and afternoon training times. From a practical point of view, strength training in the morning and afternoon hours can be similarly efficient when aiming for muscle hypertrophy over a shorter period of time (