Podcasts about Joslin Diabetes Center

In Episode 218 OF GROWING OLDER LIVING YOUNGER, Dr. William Hsu, endocrinologist and Chief Medical Officer at L Nutra, joins Dr. Gillian Lockitch to explore the science behind fasting mimicking diets (FMD) and how they may lower biological age, fight chronic disease, and boost metabolic health. You'll hear how simple lifestyle interventions, when structured and supported, can trigger the body's natural repair systems—and why healthspan, not just lifespan, should be the goal of aging well.  Dr. William Hsu is a Harvard-trained endocrinologist who spent 20 years at Harvard's Joslin Diabetes Center before joining L-Nutra in 2019 as Chief Medical Officer. At L-Nutra, he leads clinical development and drives education around fasting and the Fasting Mimicking Diet. Previously, he served as Vice President at Joslin, leading international education and healthcare advisory efforts, helping to shape national diabetes care guidelines. Dr. Hsu's research focuses on diabetes pathophysiology and digital health in chronic care. He earned degrees from Cornell and Mount Sinai, completed his Internal Medicine residency at Yale, and his Endocrinology fellowship at Harvard, where he was later an Assistant Professor.   Episode Timeline: 0:00 – Introduction and Podcast Overview Host Dr. Gillian Lockitch introduces the theme for 2025: “Age is just a number.” She frames the episode around exploring strategies to extend healthspan—the years of life spent in good health—and invites listeners to book one-on-one sessions.  2:12 – Meet Dr. William Hsu Gillian introduces her guest, Harvard-trained endocrinologist Dr. William Hsu. Formerly with the Joslin Diabetes Center, Dr. Hsu now leads clinical efforts at L- Nutra, pioneering fasting-mimicking nutrition science.  4:50 – Lifestyle Change: More Than Just Willpower Dr. Hsu explains why lifestyle interventions often fail without structural support. He acknowledges the essential role of medications but stresses the need for more systemic, pragmatic solutions to improve public health.  9:29 – Why Modern Life Challenges Healthy Living The conversation turns to the external forces—processed foods, advertising, time scarcity—that sabotage health. Dr. Hsu advocates for societal-level interventions and introduces fasting mimicking diets (FMD) as a practical tool.  12:24 – What is a Fasting Mimicking Diet? Dr. Hsu defines the FMD as a plant-based meal plan that tricks the body into a fasting state while providing nourishment. He explains how FMD promotes autophagy, cellular renewal, and metabolic reset.  28:23 – Clinical Trials: Reversing Biological Age Dr. Hsu cites a Nature Communications study where FMD reduced participants' biological age by 2.5 years in just three cycles. He explains how biological age is measured and why it's a more powerful indicator than the number on your birthday cake.  31:53 – Can You Track Your Own Biological Age? Gillian and Dr. Hsu discuss current tools for measuring biological age and where the science is heading. Dr. Hsu shares how consumers can access FMD kits and programs in various global regions.  33:14 – FMD and Diabetes Management Dr. Hsu shares compelling data showing how FMD can reduce visceral fat, insulin resistance, and blood sugar levels—attacking the root of type 2 diabetes and reducing reliance on medication.  36:09 – El Nutra's Comprehensive FMD Program Dr. Hsu describes a complete support system for FMD users, including medical oversight, apps, coaching, and lab tracking. The program is already in use in the U.S., UK, and Italy, and expanding.  39:22 – Final Thoughts: Healing Through the Right Environment Dr. Hsu emphasizes the body's innate ability to rejuvenate when supported by evidence-based nutrition like FMD. Gillian closes with a call to action: explore the tools discussed to take control of your aging journey.  Action Steps:  Check out posts in the Age is Just a Number 2025  A to Z Blogging Challenge Schedule a one on one call with Dr. Gillian Lockitch.  Join the Growing Older Living Younger  Community: https://www.facebook.com/groups/growingolderlivingyounger Access Your Free E-book from Dr. Gillian Lockitch Guide to Mind and Memory Boosting Strategies   Learn about the work of Dr. William Hsu and L-Nutra https://prolonfast.ca/ https://www.twitter.com/lnutraofficial/ https://www.facebook.com/LNutra/ https://www.linkedin.com/in/william-hsu-md/  

Episode 32 -Heidi Quinn - Evaluating Nutrition in Children with Autism In this episode of Nutrition Pearls: the Podcast, co-hosts Nikki Misner and Jen Smith speak with Heidi Quinn on nutrition in patients with Autism Spectrum Disorder.  Heidi Is a registered dietitian working in the field of pediatric/young adult nutrition with special health care needs for 35 years across various settings which includes inpatient and outpatient settings at Franciscan Children's Hospital (Brighton) , Boston Children's Hospital, Early Intervention programs, schools for children with special needs, and specialty clinics ( feeding clinics, developmental disability programs) and Joslin Diabetes Center. Heidi currently works at Boston Children's Hospital providing nutrition care  in multiple clinics including the out-patient GI clinic, the Growth and Nutrition Program, Autism/GI clinic, Cleft lip and Palate program and the Endocrine department. It is her work in the Autism/GI clinic which will be the focus of this episode.Nutrition Pearls is supported by an educational grant from Mead Johnson Nutrition.Resources:How Food Chaining Therapy Works: A Solution for Picky Eaters  Autism Spectrum Disorder in Children and Adolescents: Complementary and Integrative Medicine Therapies - UpToDateThe Managing Medical Issues in Autism video series developed by Tim Buie, Co-Director of the GI and Autism Clinic, Sonia Ballal, Stacy Kahn, Howard Shane and Julia Carmody. All 5 videos are free to families, caregivers and professionals.  Link to all the videos on the Boston Children's Hospital YouTube channel: https://bit.ly/BuieVideosProduced by: Corey IrwinNASPGHAN - Council for Pediatric Nutrition Professionalscpnp@naspghan.org

Sifting through the overwhelming amount of books, news articles, social media influencers, pop-up speaker events, and retreats for menopause is overwhelming, confusing, and expensive. How should midlife women navigate menopause feeling lost, alone, and confused by conflicting information that is supposed to make us healthier, stronger, and more resilient?There's a lot of trial and error and good money spent on products, providers, treatments, and at-home devices that don't live up to their promises. Today, you will walk away with golden nuggets of evidence-based and practical strategies to help you navigate midlife and beyond. This episode covers how to know if the information that you are hearing or reading is evidence-based, why research on women in menopause is complicated to decipher, the nuances of weight resistance training versus cardio exercise, what's most important for midlife women nutritionally, and how to properly eat around your workouts. We also cover how to read protein powder labels and what to look for in amino acids, why creatine is a game-changer for women beyond muscle health, and how to strategize getting restorative sleep. Dr. Rachele Pojednic is an international authority on nutrition, supplementation, and physical activity interventions for muscle physiology, performance, and recovery. She received her PhD from Tufts University Friedman School of Nutrition Science and Policy and completed her postdoctoral training at Harvard Medical School at the Joslin Diabetes Center and Spaulding Rehabilitation Hospital. She has a faculty appointment at Stanford University and holds research appointments at the Institute of Lifestyle Medicine at Harvard Medical School and Edith Cowan University's Nutrition and Health Innovation Research Institute. She has received NIH research funding from the National Heart Lung and Blood Institute (NHLBI) and the Vermont Biomedical Research Network (VBRN), an NIH IDeA Network of Biomedical Research Excellence (INBRE) program. She currently serves on the Board of Governors for the American College of Sports Medicine (ACSM) Exercise Is Medicine® initiative. Dr. Pojednic has been an active fitness professional for over 20 years as a nutrition educator and coach for Olympic, Division I sports, and tactical athletes. She has a passion for science communication and is regularly featured in outlets such as NPR, Sirius Doctor Radio, Time, the Wall Street Journal, STAT News, Popular Science, Self, Shape, Women's Health, Forbes, and Runners World.Medical Disclaimer:By listening to this podcast, you agree not to use this podcast as medical advice or to make any lifestyle changes to treat any medical condition in yourself or others. Consult your physician for any medical issues that you may be having. This entire disclaimer also applies to any of the guests on my podcast.Connect with Rachele:Website: https://www.rachelepojednic.com/IG: @rachelepojednic2004 YouTube: @RachelePojednic_PhDCourses: https://strongprocess.com/Stay connected with JFW:Watch on my YouTube channel: https://www.youtube.com/@jillfooswellness/videosFollow me on Instagram: https://www.instagram.com/jillfooswellness/Follow me on Facebook: https://www.facebook.com/jillfooswellnessGrab discounts on my favorite biohacking products: https://www.jillfooswellness.com/health-productsEnjoy 20% savings and free shipping at Fullscript for your favorite supplements by leading brands:https://us.fullscript.com/welcome/jillfooswellnessSubscribe to the JFW newsletter at www.jillfooswellness.com and receive your FREE Guide on How To Increase Your Protein in 5 Easy Steps and your free Protein Powder Recipe Ebook. Schedule your complimentary 30-minute Zoom consultation here:https://calendly.com/jillfooswellness/30-minute-zoom-consultations

host Dave Sobel interviews RJ Kedziora, the co-founder of Estenda Solutions, a company specializing in software, data analytics, and AI for the healthcare industry. RJ shares insights into the innovative work his firm does, focusing on digital health solutions that aim to improve the health and wellness of individuals. He highlights two key projects, including a diabetic retinopathy surveillance program in partnership with the Joslin Diabetes Center and the Indian Health Services, as well as the development of digital weight loss solutions for startups.The conversation delves into the evolution of AI technology and its impact on the healthcare sector. RJ emphasizes the shift towards making AI more accessible to non-technical users, enabling them to leverage data analytics and AI tools without deep technical expertise. He discusses the importance of structured data and data strategy in preparing for AI implementation, emphasizing the need for a solid foundation in data management and privacy compliance within the healthcare industry.RJ also shares insights into the practical applications of AI in software development and product development processes. He highlights the efficiency gains and productivity enhancements that AI tools bring to the table, enabling developers to streamline tasks such as data querying, report generation, and user interviews. The conversation underscores the importance of understanding AI frameworks and tools to maximize their benefits in various development workflows.The episode concludes with a focus on the current customer conversations around AI adoption in healthcare. RJ notes that many customers are eager to explore AI solutions but often require guidance on where to start and how to leverage data effectively. The discussion highlights the healthcare industry's gradual embrace of data-driven technologies and the ongoing challenges in integrating AI into existing workflows.  Supported by: https://getthread.com/mspradio/  All our Sponsors: https://businessof.tech/sponsors/ Do you want the show on your podcast app or the written versions of the stories? Subscribe to the Business of Tech: https://www.businessof.tech/subscribe/Looking for a link from the stories? The entire script of the show, with links to articles, are posted in each story on https://www.businessof.tech/ Support the show on Patreon: https://patreon.com/mspradio/ Want our stuff? Cool Merch? Wear “Why Do We Care?” - Visit https://mspradio.myspreadshop.com Follow us on:LinkedIn: https://www.linkedin.com/company/28908079/YouTube: https://youtube.com/mspradio/Facebook: https://www.facebook.com/mspradionews/Instagram: https://www.instagram.com/mspradio/TikTok: https://www.tiktok.com/@businessoftechBluesky: https://bsky.app/profile/businessoftech.bsky.social

In this episode, we talk about brown fat and some new discoveries in how it regulates metabolic function. Joining host Aaron Lohr is Marsel Lino, PhD, a research fellow at Joslin Diabetes Center in Boston. Dr. Lino presented an abstract at ENDO 2024 titled, “A New Layer of Endocrine Regulation: Brown Fat Secretes Exosomal MicroRNAs, Which Regulate Metabolic Functions and Distal Organs.” Show notes are available at https://www.endocrine.org/podcast/enp89-brown-fat-and-metabolic-function — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Diabetes affects one in six people in Malaysia, and is one of the top causes of death, as slightly over half (56%) of patients do not have good blood glucose control. We face multiple challenges in reducing the impact of diabetes, including poor compliance to treatment and progression of the disease towards complications. Can precision medicine guide us in adopting a different approach to diabetes management? We find out from Dr Tye Sok Cin, a postdoctoral researcher with the Section on Genetics and Epidemiology, Joslin Diabetes Center, Harvard Medical School. (Sok Cin recently received the first-ever Andrew P. Goldberg Early Career Award by the American Diabetes Association for her work in diabetes research.)Image credit: Tridsanu Thopet via Shutterstock

Guest: Elena Toschi, MD Approximately over the last decade, lifespans in the general population have increased, along with a rise in the prevalence of type 1 diabetes in older adult patients. Since each patient has a unique disease, the clinician should personalize and devise the best approach to diabetes management and glycemic targets, as well as manage comorbidities and complications. To learn more, join Dr. Elena Toschi, Director of the Young Adult Program at Joslin Diabetes Center and Assistant Professor of Medicine at Harvard Medical School.

Guest: Elena Toschi, MD Approximately over the last decade, lifespans in the general population have increased, along with a rise in the prevalence of type 1 diabetes in older adult patients. Since each patient has a unique disease, the clinician should personalize and devise the best approach to diabetes management and glycemic targets, as well as manage comorbidities and complications. To learn more, join Dr. Elena Toschi, Director of the Young Adult Program at Joslin Diabetes Center and Assistant Professor of Medicine at Harvard Medical School.

Alvin and German conduct a great conversation with Biogen's, Biomedical Scientist, Nadine Joseph.'03. As a recipient of the NIH Dissertation Award, she boasts a background in the biotechnology sector, focusing her research on the molecular intricacies of learning, memory, and neurodegeneration. Passionate about bridging health disparities and promoting inclusivity in academia, she pursued her doctoral studies at The Scripps Research Institute after completing her undergraduate degree at Colgate University. Additionally, she holds a Master of Science degree from the University of Connecticut. Her academic journey also included research stints at esteemed institutions such as the Massachusetts Institute of Technology (MIT) and the Joslin Diabetes Center. During her time at Colgate, she actively engaged in various student organizations, including AASA and Sojourners, while also fulfilling the role of Resident Advisor for two years. She received her Bachelor of Arts in Education.

We BACK! Ok...so we went biweekly for February...thanks for sticking with us! We cover all the good stuff this week including: How Nina is fueling her runsA (hot take?) AG1 reviewHow we plan our racing seasonWhy Kara shouldn't be allowed to have subscription servicesWe also have a Nutrition Corner this week covering how and why it's important to fuel right after your runs. Help Maddie raise money for the Joslin Diabetes Center and the High Hopes Fund as she prepares to run the Boston Marathon.RSVP to Mug Club!Connect with us: @trailmix_pod on Instagram, Follow Nina and KaraLooking for a coach or sports nutritionist? Nina's your girl!Support us on Patreon! Thank you!!Join the gear swap! Got a question or topic suggestion?  Send us an email trailmixsisters@gmail.comKeep it wild!

Aye! We back baby, sorry for the unintentional week hiatus...life happens and we are busy folk outside of this podcast. This week on the Trail Mix podcast it's a good ole fashioned catch up. We do some catching up with each other, tend to some housecleaning, and make 2 big and exciting announcements. Check it out!  Help Maddie raise money for the Joslin Diabetes Center and the High Hopes Fund as she prepares to run the Boston Marathon.Connect with us: @trailmix_pod on Instagram, Follow Nina and KaraLooking for a coach or sports nutritionist? Nina's your girl!Support us on Patreon! Thank you!!Join the gear swap! Got a question or topic suggestion?  Send us an email trailmixsisters@gmail.comKeep it wild!

About The Podcast. The Eavesdrop Podcast is a women's wellness podcast The Eavesdrop is a Women's Health Podcast that was created to educate, inform, and empower women to take charge of their physical, spiritual, and mental health. While the platform was created to discuss women's health concerns, no topic is ever off limits! Enjoy all inclusive conversations that will explore social issues affecting women, relationships, fashion tips, pop culture, and so much more! This Week's Episode. As we kick off Black History Month, we are having a candid conversation with Sue-Ellen Anderson-Haynes, MS, RDN,CDCES, LDN, NASM-CPT about Black Maternal Health and Mortality. Some conditions in pregnancy that affect African American Women disproportionately include: Pregnancy Induced Hypertension, Preeclampsia, Gestational Diabetes, and Postpartum Hemorrhage. Today we will review Gestational Diabetes and have a discussion about self advocacy and how to lower your risk of maternal and infant mortality and morbidity. If you are currently pregnant, considering pregnancy, recently given birth....This is the episode for you. About Sue-Ellen Anderson-Haynes Sue-Ellen is a co-author, health writer, speaker, recipe developer, and co-founder of cultured health (an app that connects dietitians to clients based on culture). She has been featured in multiple media outlets including PubMed, Insider, Harvard Health Publishing, EverdayHealth and more. Her experience includes working with many age groups in the areas of pediatrics, women's health, wellness, bariatrics, weight management and diabetes. She has training in the prenatal, pregnancy, and postpartum population from the worlds leading diabetes center - Joslin Diabetes Center in Boston Massachusetts, in addition, to other outpatient clinics, wellness centers, and hospitals across the U.S. She is a National Media Spokesperson for the Academy of Nutrition and Dietetics, Certified Diabetes Care and Education Specialist, National Academy of Sports Medicine Women's Fitness Specialist and holds her Certificate of Training in Adult Weight Management. She obtained her Masters of Science from Andrews University in Nutrition & Wellness, Summa Cum Laude, and Bachelors of Science in Food Science & Human Nutrition with minor in Health Science Education from the University of Florida. She is an active member of local, state, and national nutrition organizations. At the end of the day, she is first a wife and mother to her children and likes to be called “the organizer” of her home. She enjoys helping girls and women journey naturally to complete wellness, spending quality time with her family and cooking many dishes especially her traditional Jamaican meals. Learn More About Sue-Ellen Anderson-Haynes Follow on Instagram @360girlsandwomen @Gestational_Diabetes_Dietitian Check out her website: www.360girlsandwomen.com Follow on Facebook: 360girls&women Follow and Learn more about The Eavesdrop The Eavesdrop Instagram : IG @ therealeavesdrop_podcast ⁠The Eavesdrop Website⁠: www.theeavesdroppodcast.com ⁠ The Eavesdrop Twitter ⁠ Follow @ Drshalonnab Women's Health Telemedicine Services. Perfect Harmony Telemed www.perfectharmonytelehealth.com Perfect Harmony Women's Health Telemedicine: IG @perfectharmony_telemed

Help Maddie raise money for the Joslin Diabetes Center and the High Hopes Fund as she prepares to run the Boston Marathon.Women who inspire us: Katie Grossman Connect with us: @trailmix_pod on Instagram, Follow Nina and KaraLooking for a coach or sports nutritionist? Nina's your girl!Support us on Patreon! Thank you!!Join the gear swap! Got a question or topic suggestion?  Send us an email trailmixsisters@gmail.comKeep it wild!

We are back this week with a good ole fashioned hodge podge of topics spanning from some much needed house cleaning, to a gel review, and finishing off with our go to kits for running in the cold. Also...we have a special announcement about Patreon! Help Maddie raise money for the Joslin Diabetes Center and the High Hopes Fund as she prepares to run the Boston Marathon. Connect with us: @trailmix_pod on Instagram, Follow Nina and KaraLooking for a coach or sports nutritionist? Nina's your girl!Support us on Patreon! Thank you!!Join the gear swap! Got a question or topic suggestion?  Send us an email trailmixsisters@gmail.comKeep it wild!

Join us for a candid discussion on how vaccines can lead to healthier outcomes for people living with diabetes. Our panelists will discuss the value of vaccines in communities of color, which vaccines are most effective in living well for those with diabetes, and how our community partners and advocacy organizations are a catalyst to promoting the value of vaccination. Moderator Anna Norton, MS President, Center for Sustainable Health Care Quality & Equity, National Minority Quality Forum Anna Norton has worked in the non-profit sector for 25 years as an advocate, fundraiser, speaker, and leader. She has been featured in an assortment of health-related magazines and books, including Balancing Pregnancy with Pre-Existing Diabetes, A Woman's Guide to Diabetes: A Path to Wellness and Diabetic Living. Anna graduated with a Bachelor of Science from the University of Florida and Master of Science in Education at Florida International University. Panelists Diana Isaacs, PharmD, BCPS, BC-ADM, BCACP, CDCES, FADCES, FCCP Endocrinology Clinical Pharmacy Specialist Cleveland Clinic Diana Isaacs, PharmD, BCPS, BC-ADM, BCACP, CDCES, FADCES, FCCP is an Endocrinology Clinical Pharmacy Specialist. She serves as the Co-Director of Endocrine Disorders in Pregnancy and the Director of Education and Training in Diabetes Technology at the Cleveland Clinic Endocrinology and Metabolism Institute. Dr. Isaacs earned her bachelor's degree in chemistry from the University of Illinois at Chicago, Doctor of Pharmacy Degree from Southern Illinois University Edwardsville (SIUE) and completed a pharmacy practice residency at the Philadelphia Veterans Affairs. Dr. Isaacs holds board certifications in pharmacotherapy, ambulatory care, and advanced diabetes management. She served on the American Diabetes Association (ADA) Professional Practice Committee from 2020-2023, the committee that updates the ADA Standards of Care. She is a National Board Member of the Association of Diabetes Care and Education Specialists (ADCES). Tasha Berry-Lewis Health Ministry Director New Spiritual Light Missionary Baptist Church Tasha R. Berry-Lewis is a Health Advocate based in the Chicagoland area. She brings a wealth of experience from her previous role in the federal government, where she specialized in Human Resources, focusing on Labor and Employee Relations, Benefits, Training, and Payroll. Tasha is also a distinguished 20-year military veteran, serving during the Gulf War in Dharan, Saudi Arabia. Since 2021, Tasha has been a part of the National Minority Quality Forum - Faith Health Alliance, where she has been providing educational services to churches in the Chicagoland area on various health-related topics, including influenza, and COVID-19 vaccines. Kristian Hurley Senior Vice President of Programs, Advocacy and Health Equity, Beyond Type 1 Kristian Hurley is the Senior Vice President of Programs, Advocacy, and Health Equity at Beyond Type 1, a global nonprofit that helps people living with diabetes to stay alive and thrive. She is an experienced leader with a history of tripling health impact and revenue by inspiring transformative change in communities through building coalitions to increase health equity. Dr. Enrique Caballero, MD Endocrinologist/Investigator, Division of Endocrinology Diabetes and Hypertension, Division of Global Health Equity, Brigham and Women's Hospital Dr. Caballero is an Endocrinologist, Clinical Investigator and Educator. He is the Faculty Director of International Innovation Programs and Faculty Director of Diabetes Education in the Office for External Education at Harvard Medical School. Dr. Caballero founded the Latino Diabetes Initiative at the Joslin Diabetes Center and the Diabetes Program within the Spanish Clinic at the Brigham and Women's Hospital, both affiliated with Harvard Medical School. He is currently Associate Scientist in the Division of Global Health Equity at the Brigham and Women's Hospital in Boston.

Episode 024: Harsh Thakkar (@harshvthakkar) engages in a riveting discussion with RJ Kedziora (@RJKedziora), Co-Founder / Partner and Solutions Architect Estenda Solutions, Inc.In this episode, RJ uncovers the ins and outs of blending clinical information with imaging data, especially for patients with chronic conditions like diabetes and hypertension. RJ also dives into how data management has evolved and the exciting opportunities AI brings to healthcare. Harsh and RJ also explore the regulatory landscape surrounding AI in healthcare, discussing the EU and FDA's risk-based approach towards medical devices and AI applications. They emphasize the importance of transparency, data governance, and addressing biases in AI training datasets to ensure the technology serves a diverse population effectively.-----Links:*Estenda Solutions, Inc. Website*Upcoming HLTH Conference in Las Vegas*Would you rather watch the video episode? Subscribe to full-length videos on our YouTube channel.-----Show Notes:(5:45) Using AI in healthcare with examples from Joslin Diabetes Center. (10:47) AI in healthcare, data quality, and regulations. (15:59) AI in healthcare, data bias, and integration.(24:31) Digital health data analysis and expertise needed.(29:19) AI security challenges and solutions.For more, check out the podcast website - www.lifesciencespod.com

Check out “Heard on the Street” recorded during the ADA 2023 Conference. Hear from Dr. Jason Gaglia at Joslin Diabetes Center as he shares his exciting poster: Novel autologous dendritic cell therapy AVT001 for type 1 diabetes.

Check out “Heard on the Street” recorded during the ADA 2023 Conference. Hear from Shilton Dhaver at Joslin Diabetes Center as he shares his poster: relationship between glycemic control and body weight in non-alcoholic fatty liver disease in patients with type 1 diabetes.

Chet Galaska discusses everything you need to know about diabetes from the perspective of those who have it. It's not as well understood by the general public as you'd think and this can lead to stigmas being placed on those who have the disease. -- Chet Galaska graduated from the University of Hartford with a Bachelor of Science in Business Administration. After working in several industrial operations, he co-founded and was president of a company that produces stainless steel castings for heavy industry. He has had type 1 diabetes since 1981 and has managed it well. Because of this he was asked to participate in a long term study by the Joslin Diabetes Center at Harvard University. Chet isn't a health care professional. He is simply a person who understands diabetes and sees the disease from the perspective of those who have it. It became clear to him that messaging about the disease underlies misperceptions that have damaging consequences. This is a huge problem in the world of diabetes that doesn't get recognized, let alone addressed. He realized that people need to know the facts if we're to motivate diabetics to do the hard things the disease demands. As a first step, he wrote The Diabetes Book: What Everyone Should Know and spoke to many groups about it. He then developed the Challenge Diabetes Program which was presented in participation with college, medical, civic, business, church and other organizations. In recognition of this work he was presented the Heroes Walking Among Us Award by the Massachusetts Foot and Ankle Society. These are doctors who deal first-hand with the consequences of diabetes ignorance. His purpose is to create an informed and supportive social environment that respects diabetics who fight the beast and encourages those who don't to take it seriously. He appears on podcasts to reach as many people as possible.

A new research paper was published on the cover of Aging (Aging-US)) Volume 15, Issue 2, entitled, “Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity.” Type 2 diabetes is partly characterized by decreased β-cell mass and function which have been linked to cellular senescence. Despite a low basal proliferative rate of adult β-cells, they can respond to growth stimuli, but this proliferative capacity decreases with age and correlates with increased expression of senescence effector, p16Ink4a. In a new study, researchers Nadine Bahour, Lucia Bleichmar, Cristian Abarca, Emeline Wilmann, Stephanie Sanjines, and Cristina Aguayo-Mazzucato from the Joslin Diabetes Center at Harvard Medical School hypothesized that selective deletion of p16Ink4a-positive cells would enhance the proliferative capacity of the remaining β-cells due to the elimination of the local senescence-associated secretory phenotype (SASP). “We aimed to investigate the effects of p16Ink4a-positive cell removal on the mass and proliferative capacity of remaining β-cells using INK-ATTAC mice as a transgenic model of senolysis.” Clearance of p16Ink4a-positive subpopulation was tested in mice of different ages, males and females, and with two different insulin resistance models: high-fat diet (HFD) and insulin receptor antagonist (S961). Clearance of p16Ink4a-positive cells did not affect the overall β-cell mass. β-cell proliferative capacity negatively correlated with cellular senescence load and clearance of p16Ink4a positive cells in 1-year-old HFD mice improved β-cell function and increased proliferative capacity in a subset of animals. Single-cell sequencing revealed that the targeted p16Ink4a subpopulation of β-cells is non-proliferative and non-SASP producing whereas additional senescent subpopulations remained contributing to continued local SASP secretion. “In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes.” DOI: https://doi.org/10.18632/aging.204483 Corresponding Author: Cristina Aguayo-Mazzucato - cristina.aguayo-mazzucato@joslin.harvard.edu Keywords: beta cells, mass, proliferation, senolysis, senescence Sign up for free Altmetric alerts about this article: https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.204483 About Aging-US: Launched in 2009, Aging (Aging-US) publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at www.Aging-US.com​​ and connect with us: SoundCloud - https://soundcloud.com/Aging-Us Facebook - https://www.facebook.com/AgingUS/ Twitter - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://youtube.com/Aging-US LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM

Videos: BOMBSHELL docs reveal Covid-19 COVER-UP goes straight to the top | Redacted with Clayton Morris – Whiselblower Sasha Latypova My Apology Letter Regarding My Friendship with Jordan Peterson (THE SAAD TRUTH_1365) Harari: “With this kind of surveillance [under the skin], (you can detect dissent). I mean, you watch the big President, the big leader, give a speech on television — the television could be monitoring you and knowing whether you're angry or not just by analyzing the cues.” MacDonald Brainwashed (Tom words of wisdom) – The Rap   Eating almonds daily boosts exercise recovery molecule by 69% among ‘weekend warriors' Appalachian State University, January 6, 2023 For those who exercise regularly, eating almonds each day might be the ideal new year's resolution. A randomized controlled trial in Frontiers in Nutrition showed that female and male participants who ate 57g almonds daily for one month had more of the beneficial fat 12,13-dihydroxy-9Z-octadecenoic acid (12,13-DiHOME) in their blood immediately after a session of intense exercise than control participants. This molecule, a so-called oxylipin (oxidized fat) is synthetized from linoleic acid by brown fat tissue, and has a beneficial effect on metabolic health and energy regulation. Corresponding author Dr. David C Nieman, a professor and director of the Appalachian State University Human Performance Laboratory at the North Carolina Research Campus, said, “Here we show that volunteers who consumed 57g of almonds daily for one month before a single ‘weekend warrior' exercise bout had more beneficial 12,13-DiHOME in their blood immediately after exercising than control volunteers. They also reported feeling less fatigue and tension, better leg-back strength, and decreased muscle damage after exercise than control volunteers.” The clinical trial involved 38 men and 26 women between the ages of 30 and 65, who didn't engage in regular weight training. Approximately half were randomized to the almond diet group, and the other half to the control group, who daily ate a calorie-matched cereal bar. The researchers took blood and urine samples before and after the four-week period of dietary supplementation. Performance measures included a 30 second Wingate anaerobic test, a 50 meter shuttle run test, and vertical jump, bench press, and leg-back strength exercises. Additional blood and urine samples were taken immediately after this 90 minute session of ‘eccentric exercise' and daily for four days afterwards.  As expected, the 90 minute exercise led to an increase in the volunteers' self-reported feeling of muscle damage and muscle soreness, as well as an increased POMS score, indicating self-reported decreased vigor and increased fatigue, anxiety, and depression. The exercise also resulted in transient elevated levels of pro-inflammatory cytokines such as IL-6, IL-8, IL-10, and MCP-1 in the blood, consistent with minor muscle damage. However, these changes in cytokines were equal in the almond and cereal bar groups. Importantly, immediately after exercise, the concentration of the beneficial 12,13-DiHOME was 69% higher in blood plasma of participants in the almond group than in participants in the control group. 12,13-DiHOME is known to increase the transport of fatty acid and its uptake by skeletal muscle, with the overall effect of stimulating metabolic recovery after exercise. The reverse pattern was found for another oxylipin, the mildly toxic 9,10-Dihydroxy-12-octadecenoic acid (9,10-diHOME), which was 40% higher immediately after exercise in the blood of the control group than in the almond group. Unlike 12,13-DiHOME, 9,10-diHOME has been shown have negative effects on overall health and the body's recovery to exercise. Nieman and colleagues concluded that daily consumption of almonds leads to a change in metabolism, downregulating inflammation and oxidative stress from exercise and enabling the body to recover faster. “We conclude that almonds provide a unique and complex nutrient and polyphenol mixture that may support metabolic recovery from stressful levels of exercise. Almonds have high amounts of protein, healthy types of fats, vitamin E, minerals, and fiber. And the brown skin of almonds contains polyphenols that end up in the large intestine and help control inflammation and oxidative stress,” said Nieman. Omega-3 supplements can prevent childhood asthma Copenhagen University Hospital, December 29, 2022 Taking certain omega-3 fatty acid supplements during pregnancy can reduce the risk of childhood asthma by almost one third, according to a new study from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC) and the University of Waterloo. The study, published in the New England Journal of Medicine, found that women who were prescribed 2.4 grams of long-chain omega-3 supplements during the third trimester of pregnancy reduced their children's risk of asthma by 31 per cent. Long-chain omega-3 fatty acids, which include eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are found in cold water fish, and key to regulating human immune response. “We've long suspected there was a link between the anti-inflammatory properties of long-chain omega-3 fats, the low intakes of omega-3 in Western diets and the rising rates of childhood asthma,” said Professor Hans Bisgaard of COPSAC at the Copenhagen University Hospital. “This study proves that they are definitively and significantly related.” The testing also revealed that women with low blood levels of EPA and DHA at the beginning of the study benefitted the most from the supplements. For these women, it reduced their children's relative risk of developing asthma by 54 per cent. “The proportion of women with low EPA and DHA in their blood is even higher in Canada and the United States as compared with Denmark. So we would expect an even greater reduction in risk among North American populations,” said Professor Stark. “Identifying these women and providing them with supplements should be considered a front-line defense to reduce and prevent childhood asthma.” “Asthma and wheezing disorders have more than doubled in Western countries in recent decades,” said Professor Bisgaard. “We now have a preventative measure to help bring those numbers down.” Currently, one out of five young children suffer from asthma or a related disorder before school age. Study shows gardening may help reduce cancer risk, boost mental health University of Colorado at Boulder, January 6, 2023 The first-ever, randomized, controlled trial of community gardening found that those who started gardening ate more fiber and got more physical activity—two known ways to reduce risk of cancer and chronic diseases. They also saw their levels of stress and anxiety significantly decrease. The findings were published in The Lancet Planetary Health. “These findings provide concrete evidence that community gardening could play an important role in preventing cancer, chronic diseases and mental health disorders,” said senior author Jill Litt, a professor in the Department of Environmental Studies at CU Boulder. “No matter where you go, people say there's just something about gardening that makes them feel better,” said Litt, who is also a researcher with the Barcelona Institute for Global Health. Some small observational studies have found that people who garden tend to eat more fruits and vegetables and have a healthier weight. But it has been unclear whether healthier people just tend to garden, or gardening influences health. Only three studies have applied the gold standard of scientific research, the randomized controlled trial, to the pastime. None have looked specifically at community gardening. To fill the gap, Litt recruited 291 non-gardening adults, average age of 41, from the Denver area. More than a third were Hispanic and more than half came from low-income households. The gardening group received a free community garden plot, some seeds and seedlings, and an introductory gardening course through the nonprofit Denver Urban Gardens program and a study partner. By fall, those in the gardening group were eating, on average, 1.4 grams more fiber per day than the control group—an increase of about 7%. The authors note that fiber exerts a profound effect on inflammatory and immune responses, influencing everything from how we metabolize food to how healthy our gut microbiome is to how susceptible we are to diabetes and certain cancers. While doctors recommend about 25 to 38 grams of fiber per day, the average adult consumes less than 16 grams. “An increase of one gram of fiber can have large, positive effects on health,” said co-author James Hebert, director of University of South Carolina's cancer prevention and control program. The gardening group also increased their physical activity levels by about 42 minutes per week. Public health agencies recommend at least 150 minutes of physical activity per week, a recommendation only a quarter of the U.S. population meets. With just two to three visits to the community garden weekly, participants met 28% of that requirement. Study participants also saw their stress and anxiety levels decrease, with those who came into the study most stressed and anxious seeing the greatest reduction in mental health issues. The study also confirmed that even novice gardeners can reap measurable health benefits of the pastime in their first season. As they have more experience and enjoy greater yields, Litt suspects such benefits will increase. Researchers shed light on how exercise preserves physical fitness during aging Joslin Diabetes Center, December 6, 2023 Proven to protect against a wide array of diseases, exercise may be the most powerful anti-aging intervention known to science. However, while physical activity can improve health during aging, its beneficial effects inevitably decline. The cellular mechanisms underlying the relationship among exercise, fitness and aging remain poorly understood.   In a paper published in the Proceedings of the National Academy of Sciences, researchers at Joslin Diabetes Center investigated the role of one cellular mechanism in improving physical fitness by exercise training and identified one anti-aging intervention that delayed the declines that occur with aging in the model organism. Together, the scientists' findings open the door to new strategies for promoting muscle function during aging.   “Our data identify an essential mediator of exercise responsiveness and an entry point for interventions to maintain muscle function during aging.”  That essential mediator is the cycle of fragmentation and repair of the mitochondria, the specialized structures, or organelles, inside every cell responsible for producing energy. Mitochondrial function is critical to health, and disruption of mitochondrial dynamics  the cycle of repairing dysfunctional mitochondria and restoring the connectivity among the energy-producing organelles — has been linked to the development and progression of chronic, age-related diseases, such as heart disease and type 2 diabetes.   “As we perceive that our muscles undergo a pattern of fatigue and restoration after an exercise session, they are undergoing this mitochondrial dynamic cycle,” said Blackwell, who is also acting section head of Immunobiology at Joslin. “In this process, muscles manage the aftermath of the metabolic demand of exercise and restore their functional capability.”  “We determined that a single exercise session induces a cycle of fatigue and physical fitness recovery that is paralleled by a cycle of the mitochondrial network rebuilding,” said first author Juliane Cruz Campos, a postdoctoral fellow at Joslin Diabetes Center. “Aging dampened the extent to which this occurred and induced a parallel decline in physical fitness. That suggested that mitochondrial dynamics might be important for maintaining physical fitness and possibly for physical fitness to be enhanced by a bout of exercise.”   Finally, the researchers tested known, lifespan-extending interventions for their ability to improve exercise capacity during aging. Worms with increased AMPK — a molecule that is a key regulator of energy during exercise which also promotes remodeling of mitochondrial morphology and metabolism — exhibited improved physical fitness. They also demonstrated maintenance of, but not enhancement of, exercise performance during aging. Worms engineered to lack AMPK exhibited reduced physical fitness during aging as well as impairment of the recovery cycle. They also did not receive the age-delaying benefits of exercise over the course of the lifespan.   Nighttime electronic device use lowers melatonin levels Brigham and Women's Hospital, December 24 2022.  The Proceedings of the National Academy of Science published the findings researchers at Boston's Brigham and Women's Hospital of a suppressive effect for evening use of light-emitting electronic devices on sleep and melatonin secretion. “Electronic devices emit light that is short-wavelength-enriched light, which has a higher concentration of blue light — with a peak around 450 nm — than natural light,” explained lead author Anne-Marie Chang. “This is different from natural light in composition, having a greater impact on sleep and circadian rhythms.”  Twelve healthy adults were randomized to read a light-emitting eBook or a printed book in dim room light approximately four hours before bedtime for five evenings. At the end of the five day period, participants switched their assignments. Blood samples collected during portions of the study were analyzed for melatonin levels.  Sleep latency, time and efficiency were assessed via polysomnography.  eBook reading was associated with more time needed to fall asleep and less rapid eye movement sleep in comparison with reading a printed book. Evening melatonin levels were suppressed by an average of 55.12% in eBook readers, while those who read printed books had no suppression. Compared to printed book reading, the onset of melatonin release in response to dim light occurred 1 ½ hours later the day following reading of an eBook. “Our most surprising finding was that individuals using the e-reader would be more tired and take longer to become alert the next morning,” Dr Chang reported. “This has real consequences for daytime functioning, and these effects might be worse in the real world as opposed to the controlled environment we used.”  “We live in a sleep-restricted society, in general,” she added. “It is important to further study the effects of using light-emitting devices, especially before bed, as they may have longer term health consequences than we previously considered.” Iron deficiency anemia associated with hearing loss Penn State University, December 29, 2022 In a study published online by JAMA Otolaryngology-Head & Neck Surgery, Kathleen M. Schieffer, B.S., of the Pennsylvania State University College of Medicine, Hershey, Pa., and colleagues examined the association between sensorineural hearing loss and conductive hearing loss and iron deficiency anemia in adults ages 21 to 90 years in the United States. Approximately 15 percent of adults report difficulty with hearing. Because iron deficiency anemia (IDA) is a common and easily correctable condition, further understanding of the association between IDA and all types of hearing loss may help to open new possibilities for early identification and appropriate treatment. For this study, using data obtained from deidentified electronic medical records from the Penn State Milton S. Hershey Medical Center in Hershey, Pa., iron deficiency anemia was determined by low hemoglobin and ferritin levels for age and sex in 305,339 adults ages 21 to 90 years; associations between hearing loss and IDA were evaluated. Of the patients in the study population, 43 percent were men; average age was 50 years. There was a 1.6 percent prevalence of combined hearing loss (defined as any combination of conductive hearing loss [hearing loss due to problems with the bones of the middle ear], sensorineural hearing loss, deafness, and unspecified hearing loss) and 0.7 percent prevalence of IDA. Both sensorineural hearing loss (SNHL; when there is damage to the cochlea or to the nerve pathways from the inner ear to the brain) (present in 1.1 percent of individuals with IDA) and combined hearing loss (present in 3.4 percent) were significantly associated with IDA. Analysis confirmed increased odds of SNHL and combined hearing loss among adults with IDA. “An association exists between IDA in adults and hearing loss. The next steps are to better understand this correlation and whether promptly diagnosing and treating IDA may positively affect the overall health status of adults with hearing loss,” the authors write.

In this episode, Francois Moreau joins us to discuss the unique interaction of a viral insulin-like peptide with the IGF-1 receptor which produces a natural antagonist. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

This is the Happy Diabetic Kitchen--- In this episode, we will hear from some of my very good friends in the diabetic community who will share their personal goals for the New Year! So, get ready! We are stepping into the New Year together exploring ideas for a happy healthy lifestyle way of eating! It's time to gather your thoughts, journals and goals for a New Year's refresh. As someone who's trying to live my best diabetic life, New Year's is an opportunity to reset, regroup, and revitalize. I want to have revolution of goals and ideas… not a revolt! Keep an open mind… Stay open to possibilities of trying something new. That said, it's best to get a head start on your New Year's resolutions now. It just isn't going to happen. But, if you stand firm in actually sticking to your resolutions this year. So, whether you want to get back on that fitness grind, sharpen certain skills or be more productive, we have invited some amazing folks who live in the diabetic space every day to tell you about their list of the top New Year's resolutions to give you inspiration for 2023. I think it will inspire you…   Our guests on the podcast: Guest New Year Resolutions Jana Smolinski (Episode # 53) - Raising a Child with Diabetes: An Interview With Jana Smolenski. Jana is a school teacher and mom who raised a type one diabetic. Annie, her daughter was diagnosed at age 5. Jana has a lot of wisdom to share about how to support a small child in growing up with this disease. Max Mr. Divabetic  - You know him as Mr. Divabetic, the fruit suit clad man-about-town. He is the resident master of ceremonies and happy healthcare anchor on Diva TalkRadio, a podcast channel featuring diabetes edu-tainment and information.  When he re-appears from the studio booth and sheds his pineapple and watermelon jacket, he transforms into the mild-mannered, yet passionate Max Szadek, the founder and executive director of Divabetic and WEGO Health Activist Award nominee. Inspired by his former boss, Luther Vandross, who suffered in silence with his diabetes, Max founded Divabetic to encourage women and their families to accept a diabetes diagnosis boldly, with a Glam More, Fear Less attitude. With a background in entertainment and armed with a team of diabetes health and wellness educators, fashionistas. Mr. Divabetic's enthusiasm is infectious, and you can follow him on Twitter, Facebook, and his world-famous blog for diabetes news, updates, and all things pop culture. “I'm on a mission to change attitudes in those affected by diabetes to stay healthy and upbeat about their care so they can continue to enjoy the glamorous life.” - Max Szadek Max the Divabetic   Janice Baker Janice Baker 25 - Interview With a Dietician    Kim Stewart Kimberly Stuart ABOUT KIM Kimberly Stuart, she holds degrees from St. Olaf College and the University of Iowa. She learned lots of interesting things at these fine institutions, none of which prepared her for the lethal cocktail of parenthood and writing. Stuart is the author of eight published novels, including the Heidi Elliott series, Act Two, Stretch Marks, Operation Bonnet, Sugar, and Heart Land. She is a frequent public speaker and is passionate about helping others live great stories. Kimberly lives, plays, works in Des Moines, Iowa, where she makes her home with one forgiving husband, three wily kids and a black Schnauzer named Scout.   Annie Smolinski 52 - Diabetes does not need to define you! Interview with Annie Smolenski, type 1 rock star!   Bill Polansky Bill Polansky Dr. Bill Polonsky is Associate Clinical Professor in Psychiatry at the University of California San Diego. He received his PhD in clinical psychology from Yale University and has served as Senior Psychologist at the Joslin Diabetes Center in Boston, faculty member at Harvard Medical School and Chairman of the National Certification Board for Diabetes Educators.    Cindy Lewis my wife/partner of 42 years. Cindy has been what I like to call a type 3 diabetic, she has been my support, my helper my supporter my diabetic champion since my diagnosis in 1998.          

Disclaimer: Intended audience is the US Healthcare Providers only. These podcasts are not a substitute for medical advice and/or services from a healthcare provider. These podcasts may not be relied upon in any way in connection with your personal health care related decisions and treatment. All such decisions and treatment should be discussed with a healthcare provider who is familiar with your individual needs. Kenneth Snow is Senior Director Medical Affairs. His responsibilities include the development and review of research studies to provide clinical evidence in support of Insulet's products. Prior to joining Insulet, Dr. Snow was Product Strategy Medical Director in the Pharmacy Services Section of CVS Health and served as Medical Director for Clinical Trial Services overseeing research projects for external clients with attention to analytical results and clinical conclusions. Prior to joining CVSHealth, Dr. Snow was Chief Medical Officer for NeuroMetrix, a medical device company involved in the diagnosis and treatment of diabetic neuropathy. Previously, Dr. Snow was on the staff of the Joslin Diabetes Center in Boston for 19 years including 5 years as Chief of the Adult Diabetes Section. In addition, he was an Assistant Professor of Clinical Medicine at Harvard Medical School. Dr. Snow attended MIT and Johns Hopkins School of Medicine. He did his internship and residency in Internal Medicine at Northwestern Memorial Hospitals in Chicago and his fellowship in Endocrinology at the New England Medical Center Hospitals in Boston. He received his MBA from the University of Massachusetts.

Dr. Devkota is Director of the Human Microbiome Research Institute at Cedars-Sinai Medical Center in LA and an Associate Professor of Medicine at UCLA, as well as an adjunct investigator at the Joslin Diabetes Center at Harvard Medical School. She has been studying the effect of diet on the gut microbiome and inflammatory diseases for the past 12 years. investigating dietary drivers of gut microbiome structure and function in inflammatory bowel diseases and metabolic diseases. Her research has been published in top journals Nature, Science, and Cell, and is funded by the National Institutes of Health. She completed her masters at the University of Illinois at Urbana-Champaign in Nutritional Sciences, her Ph.D in Molecular Metabolism and Nutrition at The University of Chicago, and her post-doctoral training at the Joslin Diabetes Center at Harvard Medical School. In this episode we discuss: Do all diseases start in the gut? Prebiotics or Probiotics? What being Vegan or Vegetarian does to your gut health How to boost your immune system This episode is brought to you by One Farm, LMNT, 1stPhorm, Inside TrackerMentioned in this episode:Visit 1st Phorm Website for Free Shippinghttp://www.1stphorm.com/drlyonGet your free LMNT Sample Pack with any purchasehttps://drinklmnt.com/drlyonInside Tracker 20% Off the Entire Storehttps://info.insidetracker.com/drlyonFREE Gut Health Superfoodhttps://onefarm.com/coupon/tvt8hasn/

Dr. Devkota is Director of the Human Microbiome Research Institute at Cedars-Sinai Medical Center in LA and an Associate Professor of Medicine at UCLA, as well as an adjunct investigator at the Joslin Diabetes Center at Harvard Medical School. She has been studying the effect of diet on the gut microbiome and inflammatory diseases for the past 12 years. investigating dietary drivers of gut microbiome structure and function in inflammatory bowel diseases and metabolic diseases. Her research has been published in top journals Nature, Science, and Cell, and is funded by the National Institutes of Health. She completed her master's at the University of Illinois at Urbana-Champaign in Nutritional Sciences, her Ph.D. in Molecular Metabolism and Nutrition at The University of Chicago, and her post-doctoral training at the Joslin Diabetes Center at Harvard Medical School.  In this episode we discuss:  Why fasting and other diets don't work  Do you really need fiber in your diet?  Why you should be worried about leaky gut  Are food additives bad for you?  This episode is brought to you by One Farm, LMNT, 1stPhorm, Inside Tracker https://www.devkotalab.com/ (Devkota Lab Website) https://www.instagram.com/suzannedevkota/ (Suzanne's IG) Mentioned in this episode: Inside Tracker 20% Off the Entire Store https://info.insidetracker.com/drlyon Visit 1st Phorm Website for Free Shipping http://www.1stphorm.com/drlyon Get your free LMNT Sample Pack with any purchase https://drinklmnt.com/drlyon FREE Gut Health Superfood https://onefarm.com/coupon/tvt8hasn/

Quantum Nurse www.quantumnurse.life presents Quantum Nurse Livestream Monday, Sept 26, 2022 @ 12:00 PM EST Guest: Dr. William Hsu Topic:  " Fasting Nutrition for Longevity Lifestyle: Leveraging what nature has designed!" https://prolonfmd.com/products/prolon-professionals Bio:  Chief Medical Officer, L-Nutra  William Hsu is a visionary innovator working at the intersection of medicine, technology, and business. During his 20-year tenure as an endocrinologist at Harvard's Joslin Diabetes Center, world-renowned research, clinical care, and education center, Dr. Hsu's research focused on the pathophysiology of diabetes and the application of health technology in chronic conditions. As Vice President at Joslin, he led International Programs, providing advisory services to hospital systems and health ministries in the design of diabetes centers and programs around the globe.  Driven to disrupt and improve the chronic care model and challenge the limitations of conventional medicine, Dr. Hsu joined L-Nutra as Chief Medical Officer in 2019, being attracted by the company's innovative Nutritechnology and the strength of the science supporting its mission.  At L-Nutra, Dr. Hsu oversees the Medical, Scientific Affairs, and Regulatory Compliance Departments, leading clinical trials and research development efforts in metabolic health, diabetes, cancer, autoimmune, and neurodegenerative diseases. Also responsible for global education, Dr. Hsu advances the effective communication of scientific outcomes, which drives the adoption of Fasting-Mimicking Technology as a tool to enhance human healthspan.  Dr. Hsu has served on multiple national-level professional committees, including the American Diabetes Association, where he helped set national Standards of Medical Care in Diabetes. He received his medical degree from Mount Sinai School of Medicine. He completed his internal medicine residency at Yale School of Medicine and his Endocrinology and Metabolism fellowship at Harvard Medical School, where he was also an Assistant Professor of Medicine. With  Grace Asagra, RN MA (Holistic Nurse, US, originally from the Phil) Podcast:  Quantum Nurse: Out of the Rabbit Hole from Stress to Bless www.quantumnurse.life Quantum Nurse - Bichute https://www.bitchute.com/channel/nDjE6Ciyg0ED/ Quantum Nurse – Apple https://podcasts.apple.com/us/podcast/quantum-nurse-out-of-the-rabbit-hole-from-stress-to-bliss/id1522579988 Quantum Nurse Earth Heroes TVhttp://www.earthheroestv.com/categories/the-freedom-broadcasters?via=grace Quantum Nurse Rumble https://rumble.com/c/c-764837 Quantum Nurse Base-12 Source Code DNA Activations - https://www.youtube.com/channel4vncZtvi2VJ0fHoiArJOA/UC-

After 20 years of a distinguished career as an endocrinologist at Harvard's Joslin Diabetes Center, Dr. William Hsu joined L-Nutra in 2019 as Chief Medical Officer. In this role, Dr. Hsu leads the clinical development effort at L-Nutra, oversees the Medical Affairs Department, and advances the education and adoption of fasting and Fasting Mimicking Diet as an innovative tool to extend human healthspan. Among his prior roles, he served as Vice President at Joslin Diabetes Center, a teaching affiliate of Harvard Medical School, responsible for its international education and healthcare advisory programs. He served on multiple national-level professional committees, including the American Diabetes Association, setting national standards of medical care in diabetes. His previous research interests focused on the pathophysiology of diabetes and the application of digital technology in chronic care. Dr. Hsu went to Cornell University for college and received his medical degree from Mount Sinai School of Medicine. He completed his Internal Medicine residency training at Yale School of Medicine and completed his fellowship training in Endocrinology and Metabolism at Harvard Medical School. He was Assistant Professor of Medicine at Harvard Medical School. Links provided: https://l-nutra.com/ https://twitter.com/lnutraofficial https://www.linkedin.com/in/william-hsu-md/

Dr. Cristina Aguayo-Mazzucato from Beta Cell Aging Lab, Joslin Diabetes Center, Harvard Medical School, discusses an editorial she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 11, entitled, “Biological age in diabetes and precision medicine.” DOI - https://doi.org/10.18632/aging.204123 (PDF download) Corresponding author - Cristina Aguayo-Mazzucato - cristina.aguayo-mazzucato@joslin.harvard.edu Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.204123 Keywords - biological age, diabetes mellitus, chronological age, DNA methylation, clinical biomarkers About Aging-US Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at http://www.Aging-US.com​​ or connect with us: SoundCloud - https://soundcloud.com/Aging-Us Facebook - https://www.facebook.com/AgingUS/ Twitter - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/agingus​ LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM

My guest this week is Dr. William Hsu. After 20 years of a distinguished career as an endocrinologist at Harvard's Joslin Diabetes Center, Dr. William Hsu joined L-Nutra in 2019 as Chief Medical Officer. In this role, Dr. Hsu leads the clinical development effort at L-Nutra, oversees the Medical Affairs Department, and advances the education and adoption of fasting and Fasting Mimicking Diet as an innovative tool to extend human healthspan. Among his prior roles, he served as Vice President at Joslin Diabetes Center, a teaching affiliate of Harvard Medical School, responsible for its international education and healthcare advisory programs. He served on multiple national-level professional committees, including the American Diabetes Association, setting national standards of medical care in diabetes. His previous research interests focused on the pathophysiology of diabetes and the application of digital technology in chronic care. Dr. Hsu went to Cornell University for college and received his medical degree from Mount Sinai School of Medicine. He completed his Internal Medicine residency training at Yale School of Medicine and completed his fellowship training in Endocrinology and Metabolism at Harvard Medical School. He was Assistant Professor of Medicine at Harvard Medical School. Topics Mentioned: Changes in the function of hormones, cells, and genes Reduction of insulin resistance, lowering the risk for type 2 diabetes and helping to reverse it Reduces oxidative stress and inflammation in the body Promotes heart health by improving blood pressure, blood triglycerides, and LDL cholesterol Induces cellular repair throughout the entire body Promotes brain health by reducing oxidative stress and brain inflammation Prevents neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's diseases Dr. Hsu gives us the backstory and knowledge we need to better understand the sacred mechanism of fasting.  Did you know that around 5-6am is when all the stress hormones surges? This is when the adrenal glands really begin to kick in. When reasonably applying fasting, there is major rejuvenation going on within the body.  As Dr. Hsu says: “If we were to reduce or take away the source of calories for a period of time, the body is in this crisis moment, so it taps inside and goes to the fats– the central fats– it asks itself: ‘what can I get rid of?' And when that fasting period passes, when the nutrients come, now the body can form new parts to rejuvenate new cells.” Fast. Re-eat. Fast. Re-eat. These are the cycles of fasting and the cells way of remaining youthful…longer! I think we all want that ;) Fun fact: Fasting affects every cell in the body– including brain cells!  After 5 days of prolonged fasting, people experience 4 levels of changes… Midsection weight loss (this fat is a source). Your body finds fasting as stress. So this is a stress that sharpens your mind & preserves your muscles.  You feel better! Clarity of the mind. Focused. You feel a sense of achievement. Your cells are rejuvenated  Dr. Hsu's pro tip? Repeat this 3x a year!  To be your healthiest yet, Dr. Hsu has provided a code! You can use “wealthywellthy” for 15% for ProLon on ProLonFMD.com or ProLonFast.com.   Links: Dr. Hsu's Twitter Dr. Hsu's Facebook Dr. Hsu's LinkedIn

Troy Finn leads campaign and fundraising efforts for the University of New Hampshire across 13 colleges and schools, athletics, centers, and institutes. He joined UNH in 2017 from Development Guild DDI where he provided campaign and fundraising counsel to institutions ranging from large, research-intensive public universities to private liberal arts colleges, schools, and non-profit organizations. Having been a member of fundraising teams during campaigns of historic magnitude at Harvard Chan School of Public Health, Columbia University Medical Center, and Dana-Farber Cancer Institute, Troy has led both front-line philanthropy efforts and back-end development operations. Troy obtained a master's degree in Management and Finance from Harvard University Extension School and a bachelor's degree in philosophy from the College of the Holy Cross. He's the youngest of ten kids and loves exploring the northern New England coast with his husband and their German Shepherds, Candide and Cunegonde.Debbie Dutton has served for the past nine years as the Vice President of Advancement and President of the Foundation at the University of New Hampshire (UNH) where she leads a team of 130 advancement professionals in the leadership phase of capital campaign that follows the University's most ambitious and successful capital campaign to date, Celebrate 150, the Campaign for UNH. During this effort, UNH has surpassed all previous records in fundraising and engagement and just closed the campaign June 2018 at $308M well above the $275M goal. Prior to this role, she served as vice president for development and alumni relations at Colby College. During her six-year tenure at Colby, and before being promoted to vice president, she served as campaign director and led the school's largest fundraising effort, the Reaching the World campaign, which surpassed its goal to raise $376 million when it concluded in 2010.Debbie's career in development began at the Maine chapter of the National Multiple Sclerosis Society. She has held development positions in major gifts and senior management at three Harvard teaching hospitals: the Massachusetts Eye and Ear Infirmary, Children's Hospital, and the Joslin Diabetes Center. She also was a senior leadership giving officer at Bates College.Debbie earned a Bachelor of Arts degree in journalism from the University of Maine and a Master of Science degree in business management from Lesley College. She lives in Kennebunk, Maine with her husband and their two children.

Regular blueberry consumption may reduce risk of dementia, study finds University of Cincinnati, May 11, 2022 Researchers found that adding blueberries to the daily diets of certain middle-aged populations may lower the chances of developing late-life dementia. The findings were recently published in the journal Nutrients.  Krikorian said his team has been conducting research on the benefits of berries for people with greater risk for Alzheimer's disease and dementia for several years.  The researchers enrolled 33 patients from around the Cincinnati area between the ages of 50-65 who were overweight, prediabetic and had noticed mild memory decline with aging. Krikorian said this population has an increased risk for late-life dementia and other common conditions.  Over a period of 12 weeks, the patients were asked to abstain from berry fruit consumption of any kind except for a daily packet of supplement powder to be mixed with water and consumed either with breakfast or dinner. Half of the participants received powders that contained the equivalent of one-half cup of whole blueberries, while the other half received a placebo.  Krikorian said those in the blueberry-treated group showed improvement on cognitive tasks that depend on executive control.   Patients in the blueberry group also had lower fasting insulin levels, meaning the participants had improved metabolic function and were able to more easily burn fat for energy.   Krikorian said the blueberry group displayed an additional mild degree of higher mitochondrial uncoupling, a cellular process that has been associated with greater longevity and reduced oxidative stress. Oxidative stress can lead to symptoms like fatigue and memory loss.  Regular exercise with dietary advice linked to better mobility in frail older people Yale University, May 11, 2022 A program of regular exercise along with expert dietary advice is linked to a reduction in mobility problems among frail older people living in the community, finds a trial published by The BMJ today. The combination of aerobic (walking), strength, flexibility, and balance exercises alongside personalized nutritional counseling reduced mobility disability by 22% over three years. Their findings are based on 1,519 men and women (average age 79 years) with physical frailty and sarcopenia (a combination of reduced physical function and low muscle mass) recruited from 16 clinical sites across 11 European countries between 2016 and 2019. Women in the intervention group lost less muscle strength (0.9 kg at 24 months) and less muscle mass (0.24 kg and 0.49 kg at 24 months and 36 months, respectively) than control women, but no significant group differences were seen in men.  Study: Side effects emerge after approval for many US Yale University, May 9, 2022  Almost one-third of new drugs approved by U.S. regulators over a decade ended up years later with warnings about unexpected, sometimes life-threatening side effects or complications, a newanalysis found. The results covered all 222 prescription drugs approved by the U.S. Food and Drug Administration over ten yers.  The 71 flagged drugs included top-sellers for treating depression, arthritis, infections and blood clots. Safety issues included risks for serious skin reactions, liver damage, cancer and even death. “The large percentage of problems was a surprise,” and they included side effects not seen during the review process, said Dr. Joseph Ross, the study's lead author at Yale University.”We know that safety concerns, new ones, are going to be identified once a drug is used in a wider population. That's just how it is,” Ross said.  While most safety concerns were not serious enough to prompt recalls, the findings raise questions about how thoroughly drugs are tested before approval The study counted black-box warnings for dozens of drugs; these involved serious problems including deaths or life-threatening conditions linked with the drugs. There were also dozens of alerts for less serious potential harms and three drug withdrawals because of the potential for death or other serious harm. Among the drugs with added warnings: Humira, used for arthritis and some other illnesses; Abilify, used for depression and other mental illness; and Pradaxa, a blood thinner. The withdrawn drugs and the reason: Bextra, an anti-inflammatory medicine, heart problems; Raptiva, a psoriasis drug, rare nervous system illness; and Zelnorm, a bowel illness drug, heart problems. Exercise during pregnancy may yield metabolic benefits in grandchildren Harvard University, May 11, 2022 If grandma liked working out, her pain may be your gain. It may seem unlikely, but recent research out of the Joslin Diabetes Center says it just might be the case. Laurie Goodyear, a professor of medicine at Harvard Medical School, has found that a grandmother's exercise during pregnancy may make her grandchildren healthier metabolically, with less body fat, better insulin control and, in some, healthier bones. We are looking for epigenetic alterations in the DNA, because epigenetic alterations can be changed as rapidly as two generations. We analyze micro RNAs, some methylation situations in the F1 generation eggs and sperm to see what's going on. We are currently investigating how mothers' exercise affects their children's gametes. I'm confident in saying that women who are pregnant should try to be as physically active as they can, depending, of course, on the condition of their pregnancy. There's strong human data showing that exercise during pregnancy improves the mother's health; numerous animal studies showing improved first-generation health; and now we have evidence that maternal exercise will positively impact the health of the second generation. I'm not an obstetrician, and there are certainly conditions where a woman cannot perform exercise during pregnancy, but, when medically approved, being physically active is important—for the mother, the first generation, and now even the grandchildren. New Study Finds Simply Believing You Can Do Something To Improve It Is Linked With Higher Wellbeing University Of Southern Denmark And University Of Copenhagen, May 11, 2022 The number of people struggling with poor mental health and mental disorders has been rising around the world over the past few decades. Those who are struggling are increasingly facing difficulties accessing the kind of support they need – leaving many waiting months for help, if they even qualify for treatment. In our recent study, we asked 3,015 Danish adults to fill out a survey that asked questions about mental health – such as whether they believe they can do something to keep mentally healthy, whether they had done something in the past two weeks to support their mental health, and also whether they were currently struggling with a mental health problem. We then assessed their level of mental wellbeing using the Short Warwick–Edinburgh Mental Well-being Scale, which is widely used by healthcare professionals and researchers to measure mental wellbeing. As you'd expect, we found that mental wellbeing was highest among those who had done things to improve their mental health compared with the other participants. Interestingly, however, we found that – whether or not our respondents had actually taken action to improve their mental wellbeing – people who believed they could do something to keep mentally healthy tended to have higher mental wellbeing than those who didn't have this belief. So while it's most beneficial to take steps to improve your mental health, even just believing that you can improve it is associated with better overall mental wellbeing.The effect of night shifts—gene expression fails to adapt to new sleep patterns McGill University (Quebec).  May 7, 2022  Have you ever considered that working night shifts may, in the long run, have an impact on your health? A team of researchers from the McGill University has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns and that most of them stay tuned to their daytime biological clock rhythms. “We now better understand the molecular changes that take place inside the human body when sleeping and eating behaviours are in sync with our biological clock. For example, we found that the expression of genes related to the immune system and metabolic processes did not adapt to the new behaviours,” says Dr. Boivin, a full professor at McGill University's Department of Psychiatry. It is known that the expression of many of these genes varies over the course of the day and night. Their repetitive rhythms are important for the regulation of many physiological and behavioural processes. “Almost 25% of the rhythmic genes lost their biological rhythm after our volunteers were exposed to our night shift simulation. 73% did not adapt to the night shift and stayed tuned to their daytime rhythm. And less than 3% partly adapted to the night shift schedule. “We think the molecular changes we observed potentially contribute to the development of health problems like diabetes, obesity, cardiovascular diseases more frequently seen in night-shift workers on the long term,” explains Dr. Boivin.  Videos: 1. Will the Future Be Human? – Yuval Noah Harari (Start @ 2:13) 2. The Invention Of Whiteness.. (Start @ 0:28) 3. Jonathan Pie's Rant On Cultural Appropriation 4. Breakthrough deaths comprise increasing proportion of those who died from COVID-19 (5:44)

The global epidemic of diabetes and prediabetes afflicts more than 1 billion people. Sadly, more than 50% of people with diabetes do not achieve their desired glucose control. Moreover, less than 25% achieve their blood pressure, cholesterol, and glucose goals.In his book, Conquer Your Diabetes: Prevention, Control, Remission, Dr. Martin Abrahamson and his co-author Sanjiv Chopra, MD put all the pieces of the diabetes puzzle together, including a concise history of the disease, underlying types and causes, prediabetes, obesity, weight loss, pregnancy, mental health, type 2 diabetes prevention and remission, and latest treatments.Dr. Abrahamson joins us today to tell us more about his book & his diabetes research. He is an Associate Professor of Medicine at Harvard Medical School and a previous Chief Medical Officer at Joslin Diabetes Center. He lectures globally on diabetes and has spearheaded educational initiatives on diabetes for physicians around the world.

The global epidemic of diabetes and prediabetes afflicts more than 1 billion people.The global epidemic of diabetes and prediabetes afflicts more than 1 billion people. Sadly, more than 50% of people with diabetes do not achieve their desired glucose control. Moreover, less than 25% achieve their blood pressure, cholesterol, and glucose goals.In his book, Conquer Your Diabetes: Prevention, Control, Remission, Dr. Martin Abrahamson and his co-author Sanjiv Chopra, MD put all the pieces of the diabetes puzzle together, including a concise history of the disease, underlying types and causes, prediabetes, obesity, weight loss, pregnancy, mental health, type 2 diabetes prevention and remission, and latest treatments.Dr. Abrahamson joins us today to tell us more about his book & his diabetes research. He is an Associate Professor of Medicine at Harvard Medical School and a previous Chief Medical Officer at Joslin Diabetes Center. He lectures globally on diabetes and has spearheaded educational initiatives on diabetes for physicians around the world.

The global epidemic of diabetes and prediabetes afflicts more than 1 billion people.The global epidemic of diabetes and prediabetes afflicts more than 1 billion people. Sadly, more than 50% of people with diabetes do not achieve their desired glucose control. Moreover, less than 25% achieve their blood pressure, cholesterol, and glucose goals.In his book, Conquer Your Diabetes: Prevention, Control, Remission, Dr. Martin Abrahamson and his co-author Sanjiv Chopra, MD put all the pieces of the diabetes puzzle together, including a concise history of the disease, underlying types and causes, prediabetes, obesity, weight loss, pregnancy, mental health, type 2 diabetes prevention and remission, and latest treatments.Dr. Abrahamson joins us today to tell us more about his book & his diabetes research. He is an Associate Professor of Medicine at Harvard Medical School and a previous Chief Medical Officer at Joslin Diabetes Center. He lectures globally on diabetes and has spearheaded educational initiatives on diabetes for physicians around the world.

The global epidemic of diabetes and pre diabetes afflicts more than 1 billion people. And sadly, more than 50% of people with the disease do not achieve their desired glucose control. In Conquer Your Diabetes: Prevention, Control, Remission, Drs. Martin Abrahamson and Sanjiv Chopra, two Harvard Medical School professors and master clinicians, provide a road map for people with diabetes to manage their condition and live rewarding and fulfilling lives. In 25 succinct chapters—many containing stories of real patients living successfully with the condition—the authors put all the pieces of the diabetes puzzle together, including information on its types and causes as well as the latest treatments. There's even material on gestational diabetes, the connection between diabetes and heart disease, and the relatively small amount of body weight (about 7%) that most people with pre diabetes need to lose to reduce their risk of developing Type 2 diabetes by more than half. Martin Abrahamson, MD, FACP is an Associate Professor of Medicine at Harvard Medical School and previous Chief Medical Officer at Joslin Diabetes Center. He lectures globally on diabetes and has spearheaded educational initiatives on diabetes for physicians around the world. Sanjiv Chopra, MD, MACP, FRCP is a Professor of Medicine and served as the Faculty Dean for Continuing Education at Harvard Medical School for 12 years. The author or co-author of 12 previous books, including Brotherhood: Dharma, Destiny and the American Dreamwhich he co-authored with his brother Deepak, he is the recipient of many prestigious teaching awards and a sought-after speaker lecturing internationally. Together, Drs. Abrahamson and Chopra direct the Division of Continuing Medical Education (CME) at Boston's Beth Israel Deaconess Medical Center, a major teaching affiliate of Harvard Medical School, and have been conducting CME meetings for more than a quarter of a century. --- Support this podcast: https://anchor.fm/steve-richards/support

“For me, the beauty of diabetes was that it was the anchor but it allowed me to explore so many different areas of research and interest.” -Robert A. Gabbay, MD, PhD   In episode 158 of the podcast, we welcome Dr. Robert Gabbay. Dr. Gabbay is Chief Scientific and Medical Officer of the American Diabetes Association and Associate Professor at Harvard Medical School. DocWorking Founder and CEO, Dr. Jen Barna talks with Dr. Gabbay about how it all started for him, his journey in medicine, how he balances it all and what advice he was given and what advice he would give to his younger self. He speaks about difficult decisions he made that affected the direction of his career. Dr. Gabbay also talks about the importance that mentors have had in his life and how they helped to shape him.    Robert A. Gabbay, MD, PhD is Chief Scientific and Medical Officer of the American Diabetes Association and Associate Professor at Harvard Medical School. His research focuses on innovative models of diabetes care to improve diabetes outcomes and the lives of people with diabetes. Throughout his vibrant career he has had many accomplishments as a basic science researcher, developer of patient communication tools, creator of the first broad scale diabetes registry, designer of care management training programs, and leader of one of the largest primary care transformation efforts in the US around the Patient Centered Medical Home. The reach of his work has been recognized through leadership roles around the world to transform diabetes care including leading the International Diabetes Federation BRIDGES program that implements evidence based translational research to low resource global settings. Dr. Gabbay has received funding from the National Institute of Health Diabetes, Digestive and Kidneys Diseases (NIDDK), the Agency for Healthcare Research and Quality (AHRQ), and the Center for Medicare and Medicaid Innovation for his care transformation work. Along with an extensive peer reviewed publication record, his views have appeared in popular press such as the New York Times, CNN, the Washington Post, People, Oprah, and National Public Radio. Formerly, he held the role of Chief Medical Officer at Joslin Diabetes Center.   Find full transcripts of DocWorking: The Whole Physician Podcast episodes on the DocWorking Blog  DocWorking empowers physicians and entire health care teams to get on the path to achieving their dreams, both in and outside of work, with programs designed to help you maximize life with minimal time.   Are you a physician who would like to tell your story? Please email Amanda, our producer, at Amanda@docworking.com to be considered.   And if you like our podcast and would like to subscribe and leave us a 5 star review, we would be extremely grateful!   We're everywhere you like to get your podcasts! Apple iTunes, Spotify, iHeart Radio, Google, Pandora, Stitcher, PlayerFM, ListenNotes, Amazon, YouTube, Podbean   You can also find us on Instagram, Facebook, LinkedIn and Twitter.    Some links in our blogs and show notes are affiliate links, and purchases made via those links may result in payments to DocWorking. These help toward our production costs. Thank you for supporting DocWorking: The Whole Physician Podcast!   Occasionally, we discuss financial and legal topics. We are not financial or legal professionals. Please consult a licensed professional for financial or legal advice regarding your specific situation.   Podcast produced by: Amanda Taran

Some diseases run in the family, when more than one person has the same kind of illness passed down through genes. One of those genes, called APOL1, has variations that are linked to an increased risk for kidney disease, especially in under-resourced communities of color. In today's bonus episode, we discuss how a clinical research study is looking to understand the effect of APOL1 on kidney transplant outcomes from living and deceased donors, and why it's important for you to be part of this research study. In this episode, you will hear from: Marva Moxey-Mims, MD, FASN Dr. Moxey-Mims is Professor of Pediatrics at George Washington University School of Medicine and Chief of the Division of Nephrology at Children's National Health System, Washington, D.C.  Dr. Moxey-Mims serves as the Study Chair of the APOLLO Steering Committee and Chair of the Publications & Presentation Committee. Jonah Odim, MD Dr. Odim is Chief of the Clinical Transplantation Section at the National Institute of Allergy and Infectious Diseases (NIAID). Dr. Odim serves as a representative of the National Institutes of Health (NIH) on the APOLLO Steering Committee and member of the Dissemination Working Group. Glenda V. Roberts  Glenda is the Director of External Relations & Patient Engagement for the Center for Dialysis Innovation at the University of Washington Kidney Research Institute.  Glenda serves as a member of the APOLLO Community Advisory Committee, the Recruitment Committee, and the Dissemination Working Group. Sylvia E. Rosas, MD, MSCE Dr. Rosas is a nephrologist and epidemiologist at the Joslin Diabetes Center and the Beth Israel Deaconess Medical Center. Sylvia serves as the Principal Investigator of APOLLO Clinical Center 09 (Harvard University) and member of the Dissemination Working Group. Krista Lentine, MD, PhD, FAST, FAST Dr. Lentine is Medical Director of Living Donation, Co-Director of Clinical Research, and Mid-America Transplant/Jane A. Beckman Endowed Chair in Transplantation at Saint Louis University (SLU). Krista serves as co-Principal Investigator for APOLLO Clinical Center 03 (Johns Hopkins | SLU), member of the Data, Ancillary Studies, and Publications & Presentation Committees, and chair of the Dissemination Working Group. Denay Richards Ms. Richards and her family were born in the Caribbean when her mother was diagnosed with ESRD. They moved to the United States, where her mother was told that she had about 3 months to live. On August 29th, 2000, Denay's father donated a kidney to her and in 2020 they celebrated their 20 year - “kidneyversary.” As a child, Denay loved helping her mother with the dialysis process, organizing medications, and attending hospital visits. It was this exposure to the medical field that encouraged Denay to pursue a career in surgery. In 2019 she graduated from Princeton University with a degree in Molecular Biology and as of 2021 is an MD/PhD student in a dual degree program with Robert Wood Johnson Medical School and Princeton University. In 2019, she earned a double board qualification as a fitness nutrition specialist and personal trainer under the International Sports Sciences Association. In 2020, Denay was diagnosed with an APOL1 mutation that is more prevalent in the African American community and has been linked to early kidney failure. Denay says that her diagnosis has empowered her to expand education about renal health, fitness/nutrition, and genetic predispositions for kidney failure to the world, especially disenfranchised populations that are at greater risk.   Genetics and kidney disease: https://www.kidney.org/atoz/content/genetics-kidney-disease

Dr. Sanjoy Dutta, PhD, is the Chief Scientific Officer at JDRF International (https://www.jdrf.org/) a nonprofit organization that funds Type 1 Diabetes (T1D) research, provides a broad array of community and activist services to the T1D population, and actively advocates for regulation favorable to medical research and approval of new and improved treatment modalities. Dr. Dutta oversees all of JDRF's efforts to cure Type 1 Diabetes and improve the lives of those living with it, which includes beta cell therapies, immunotherapies, glucose control and related disease complications. He is also responsible for international partnerships with world-leading government, non-government, foundation and commercial organizations. Dr. Dutta joined JDRF in 2009. Prior to coming to JDRF, Dr. Dutta was the Associate Director of Translational Medicine and Clinical Biomarkers at Bristol-Myers Squibb, and Principal Scientist of Cardiovascular and Metabolic Diseases at Hoffmann-La Roche. Dr. Dutta obtained his doctorate from the department of biochemistry and molecular biology at the University of Southern California and was a JDRF Postdoctoral Fellow in the department of cell biology and the Joslin Diabetes Center at Harvard Medical School.

After 20 years of a distinguished career as an endocrinologist at Harvard's Joslin Diabetes Center, Dr. William Hsu joined L-Nutra in 2019 as Chief Medical Officer. In this role, Dr. Hsu leads the clinical development effort at L-Nutra, oversees the Medical Affairs Department, and advances the education and adoption of fasting and Fasting Mimicking Diet as an innovative tool to extend human health span. Among his prior roles, he served as Vice President at Joslin Diabetes Center, a teaching affiliate of Harvard Medical School, responsible for its international education and healthcare advisory programs. He served on multiple national-level professional committees, including the American Diabetes Association, setting national standards of medical care in diabetes. His previous research interests focused on the pathophysiology of diabetes and the application of digital technology in chronic care. Dr. Hsu went to Cornell University for college and received his medical degree from Mount Sinai School of Medicine. He completed his Internal Medicine residency training at Yale School of Medicine and completed his fellowship training in Endocrinology and Metabolism at Harvard Medical School. He was Assistant Professor of Medicine at Harvard Medical School. Dr. Hsu is exceptional at explaining the science of healing in easy to digest ways. Listen to this episode to discover how fasting mimicking contributes to longevity and health in 4 ways: 1) weight loss, 2) cellular regeneration, 3) mental health, and 4) behaviour. As of 2000, there is more evidence stating that OVER-nutrition is exceeding cases of malnutrition, obesity, and diabetes. Learn how over-nutrition is the actual culprit that kicked off the epidemic of chronic disease. Lastly, devour this show to discover how to put your body into a state Autophagy to trigger regeneration and total health and why L-Nutra helps you live longer and healthier – disease free. Find Dr William Hsu at:Website: www.L-Nutra.comProducts: www.prolonfmd.comFacebook: LNutra Join the Best Chefs in the World – Green Moustache Chef Certification - https://www.greenmoustache.com/chef-course Discussed on the PODCAST:Professor Valter Longo – www.valterlongo.comProfessor Ohsumi, 2016 Nobel prize – https://bit.ly/3qM6IgJAutophagy – https://bit.ly/3GPt9HhDr Klaper – www.drKlaper.comTrueNorth - https://bit.ly/3fILqdBNutrition for Longevity – www.nutritionforlongevity.com/Jennifer Maynard Podcast - https://youtu.be/vB95pv6U0xQArticles links - https://l-nutra.com/science/Information on Fasting - www.Fasting.com Watch the trailer for Nicolette's new film Food Of Our Ancestors coming out soon in 2021 - https://bit.ly/3CIQyr1 If you are currently battling a Chronic Degenerative Disease, Nicolette is doing one on one consultations again. Go to www.nicolettericher.com to set up an appointment today! Our 22M Bike tour is still happening once the world returns to its new normal. Find out more about and support our 22 Million Campaign here - www.richerhealth.ca/ Join Nicolette at one of her retreats https://richerhealthretreatcentre.com/ Find out more about our non-profit society Sea to Sky Thrivers - https://seatoskythrivers.com/ Want to know more about Nicolette's Green Moustache Café's https://www.greenmoustache.com/ Sign up for the Eat Real to Heal Online Course - https://nicolettericher.com/eat-real-to-heal Buy the Eat Real to Heal Book here: https://amzn.to/3nMgEFG

After 20 years of a distinguished career as an endocrinologist at Harvard's Joslin Diabetes Center, Dr. William Hsu joined L-Nutra in 2019 as Chief Medical Officer. In this role, Dr. Hsu leads the clinical development effort at L-Nutra, oversees the Medical Affairs Department, and advances the education and adoption of fasting and Fasting Mimicking Diet as an innovative tool to extend human healthspan.Among his prior roles, he served as Vice President at Joslin Diabetes Center, a teaching affiliate of Harvard Medical School, responsible for its international education and healthcare advisory programs. He served on multiple national-level professional committees, including the American Diabetes Association, setting national standards of medical care in diabetes. His previous research interests focused on the pathophysiology of diabetes and the application of digital technology in chronic care.Dr. Hsu went to Cornell University for college and received his medical degree from Mount Sinai School of Medicine. He completed his Internal Medicine residency training at Yale School of Medicine and completed his fellowship training in Endocrinology and Metabolism at Harvard Medical School. He was Assistant Professor of Medicine at Harvard Medical School.Check L-Nutra at l-nutra.com. Follow them on Twitter and Facebook. Connect with Dr. William on LinkedIn. 

Are you interested in Intermittent fasting?  Have you been struggling with chronic pain?  In this episode, we're discussing all things fasting, how it works, how it helps and so much more. Today, I interview Dr. William Hsu. After 20 years of a distinguished career as an endocrinologist at Harvard's Joslin Diabetes Center, Dr. William Hsu joined L-Nutra in 2019 as Chief Medical Officer. In this role, Dr. Hsu leads the clinical development effort at L-Nutra, oversees the Medical Affairs Department, and advances the education and adoption of fasting and Fasting Mimicking Diet as an innovative tool to extend human healthspan. We discuss the impact fasting has on the body, as well as the importance of what you choose to eat after a fast. Dr. Hsu also discusses how fasting can help with weight management and chronic pain. Questions I asked: What is intermittent fasting and why should we do it? What are the impacts of fasting on the body? How does fasting help during menopause? How does fasting help your mental health? What does fasting do for your cells? If you're fasting, can you still have coffee and tea in the morning? When should you exercise during fasting? Should we avoid a bunch of junk while fasting? How can you prepare for a fast? What should people know about fasting and eating? Why does fasting change your relationship with food? How should you balance rest and fasting? How does your protocol help people with health goals? Can you discuss why you aren't starving during a fast? What foods help with longevity and aging? Where can listeners find more about you? How often do you fast? Topics Discussed: Fasting Aging Healthy foods. Chronic pain. Sustainable weight loss. Healthy menopause. Blood Sugar. Quotes from the show: “Everybody should get on a 12:12 fasting regimen.” Dr. William Hsu @SisterhoodSweat “Fasting impacts the body on so many levels.” Dr. William Hsu @SisterhoodSweat “What could be faster for weight loss than fasting?” Dr. William Hsu @SisterhoodSweat “Every culture has fasting practices because it purifies your thoughts.” Dr. William Hsu @SisterhoodSweat “It's best to exercise in the re-feeding phase of the fast.” Dr. William Hsu @SisterhoodSweat “Mediterranean diet is best for longevity.” Dr. William Hsu @SisterhoodSweat How you can stay in touch with Dr.Hsu: LinkedIn L-Nutra Prolon Fasting Nation Facebook    Don't forget to DM me on Instagram, or email me at info@sisterhoodofsweat.com to join the Wild Horses Project!   How you can stay in touch with Linda: Website Facebook Twitter Instagram Pinterest YouTube SoundCloud   "Proud Sponsors of the Sisterhood of S.W.E.A.T" Essential Formulas

Dr. Hsu was the VP of International Programs and Medical Director of the Asian Clinic at Joslin Diabetes Center, a teaching and research affiliate of Harvard Medical School.   After 20 years of a distinguished career as an endocrinologist, Dr. William Hsu joined L-Nutra in 2019 as Chief Medical Officer.  In this role, Dr. Hsu leads the clinical development effort at L-Nutra, oversees the Medical Affairs Department, and advances the education and adoption of fasting and Fasting Mimicking Diet as an innovative tool to extend human health span.   This podcast topic is a big interest for me personally as I've been looking into the research on intermittent fasting (and caloric restriction in general) for longevity and health; but we also talk alot about body composition and fat loss here too, so if intermittent or fasting in general is of interest to you, you'll really enjoy this episode.   Here are some of the things we talked about:  ·      How fasting is a ‘good' stressor that helps the cells in our body ·      The difference between fasting and starvation  ·      Fat loss and fasting – metabolic and hormonal benefits  ·      If coffee or supplements okay to have during a fasting period ·      How to make yourself a fat burning machine ·      Autophagy for health span ·      Diets and foods in the blue zones  ·      How to use a fasting mimicking diet if you struggle with traditional fasting     Social   https://www.linkedin.com/in/william-hsu-md/   https://twitter.com/lnutraofficial?lang=en   https://www.facebook.com/LNutra/   http://l-nutra.com   BRIANS LINKS BKF Online Program: https://briankeanefitness.com/bkf-online/   GAA Lean Body Program: https://briankeanefitness.com/lean-body-program/

In today's interview we are talking to Dr. William Hsu about Intermittent Fasting and Fasting Mimicking Diet. Dr. Hsu received his medical degree from Mount Sinai School of Medicine. He completed his Internal Medicine residency training at Yale School of Medicine and completed his fellowship training in Endocrinology and Metabolism at Harvard Medical School. He was Assistant Professor of Medicine at Harvard Medical School. After 20 years of a distinguished career as an endocrinologist at Harvard's Joslin Diabetes Center, Dr. William Hsu joined L-Nutra in 2019 as Chief Medical Officer. In this role, he leads the clinical development effort at L-Nutra, oversees the Medical Affairs Department, and advances the education and adoption of fasting and Fasting Mimicking Diet as an innovative tool to extend human healthspan.HIGHLIGHTS Definition of HEALTHSPANThe very basic concept of fasting.Fasting mimicking diet.Intermittent Fasting Diet vs Prolonged Fasting or Fasting Mimicking Diet.Recommended periods of time for the Mimicking Diet depending on your health condition.The importance of re-feeding.SUGAR-FREE QUOTES"Fasting is one of the most original diets that all living organisms have been on""In our country (USA) around 86% of people die of non-communicable disease that are preventable. These are, by large, driven by the way we eat"."You don't want to do periodic fasting so often that the body doesn't have time to replete  all the nutrients."LINKS OF INTERESTLearn more on l-nutra.com Join their FB community at https://www.facebook.com/LNutra/Visit My Diabetes Concierge ProgramNeed someone to talk to about your Diabetes? Book a free consultation with Denise today https://reversemydiabetes.net/  Follow  The Virgin Diabetic on Instagram @thevirgindiabetic Get The Virgin Diabetic Book https://amzn.to/3auCJl6Sign up to the Email list  to get diabetes information and special recipes.Join us on Facebook for more info, discussions and articles https://www.facebook.com/reversemydiabetes/ 

Kate and Bella chat with entrepreneur, Holly Daniels Christensen, CEO and Founder of Dune Jewelry Co.Can you go from crafting at your kitchen table to a multi-million-dollar business?  As CEO, Holly Daniels Christensen has proved – yes!  Using grit and the actual sand beneath her toes, that's exactly what this entrepreneur has done.The founder of Dune Jewelry left home at 15 years old, and never looked back. She held a variety of jobs with stints as a zookeeper, pharmacy technician, promotional model, bartender, cellphone, car and cruise salesperson. She also spent 14 successful years as a top agent in Boston's highly competitive real estate market.  This unique bootstrap entrepreneur who proved she was unafraid of hard work was voted 2016 Woman-Owned Business of the Year for Massachusetts and New England by the Small Business Association (SBA). In 2018, Inc. magazine honored Dune Jewelry as No. 2590 on its 37th annual Inc. 5000 List which is the most prestigious ranking of the nation's fastest-growing private companies. The list represents a unique look at the most successful companies within the American economy's most dynamic segment—its independent small businesses.   Currently, Dune Jewelry is the one-and-only experiential jewelry brand in the world.It all started in 2007, when this self-taught jewelry designer began making beach sand jewelry for friends and family at her kitchen table, then officially launched Dune Jewelry full time in 2010. Now, Dune employs a team of 25 people working in a 3,100 square foot studio space in Hyde Park, Massachusetts.  Dune continuously fills orders for over 600 retail partners worldwide while their thriving e-commerce website focuses on selling personalized Experiential Jewelry that captures their customer's most cherished memories. Additionally, Holly has created an exclusive Sandbank that holds over 5,000 sands and earth elements gathered from iconic and memorable locations around the globe which customers can select from to customize their jewelry.Holly is an advocate for giving back to the community and is proud to spearhead many fundraisers each year for non-profit organizations such as SMILE Mass, Joslin Diabetes Center, and the Association to Preserve Cape Cod. In addition, Dune often donates a portion of their sales throughout the year to various charities such as the global relief organization All Hands and Hearts, the Surfrider Foundation and the P.A.W.S Project.Currently, Holly is hosting “Kitchen Table Talks” a 30-minute live show on Facebook and Instagram, where she shares updates on current events, favorite recipes, funny happenings and style hacks along with information on Dune's new brand collaborations and designs in development. Holly lives in Walpole, Massachusetts with her husband Eric, their two daughters Alexa and Lyla, and their rescue pup, Earle.  She is dedicated to creating a future that motivates people to understand that continued hard work and perseverance is a direct path to success.      Follow Holly Daniels Christensen on her personal Instagram:  sandy__handsFor more information on Dune Jewelry visit, www.dunejewelry.comFollow Dune Jewelry on social media: Instagram: DuneJewelryFacebook: www.facebook.com/dunejewelry​Twitter:  @dunejewelry

Recorded on 05/04/2021 at the East Brunswick Public Library. Learn how diabetes affects your body, including your heart, blood vessels, eyes, and kidneys and what you can do to lessen the effects. Presented by: Reema Patel, MD, FACE Medical Director, Joslin Diabetes Center, Raritan Bay Medical Center, Old Bridge Hackensack Meridian Health Board certified in diabetes, endocrinology and metabolism, and internal medicine

This episode Alex Aferiat speaks with Maria Buckley, General Counsel, Joslin Diabetes Center. Maria is alumni of Boston University and received her JD from Suffolk Law School. Maria joined Joslin as their GC in September 2012 after a long and successful career at the Boston law firm of Nutter McClennen & Fish LLP where she was part of the Healthcare and Life Sciences practice groups. Prior to Nutter, Maria was Senior Counsel at Blue Cross Blue Shield of Massachusetts. She is also the author of several publications on health law and life sciences. She was named the 2015 Leader in the Law from Mass Lawyers Weekly. Alex discusses with Maria her path to GC, how COVID-19 impacted her organization and herself as a GC and her specific passions and causes she supports.

We hear from Christopher Mulla, MD, from the Joslin Diabetes Center in Boston, about his research about the closed loop glucagon pump as a strategy for post-bariatric hypoglycemia. For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.

We hear from Christopher Mulla, MD, from the Joslin Diabetes Center in Boston, about his research about the closed loop glucagon pump as a strategy for post-bariatric hypoglycemia. For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.

John Brooks—the managing director of Healthcare Capital, LLC and former president and CEO of the Joslin Diabetes Center—is a something of a legend in the diabetes sector. As much an inventor as an investor, he brings a spirited intelligence and diverse experience to fighting this chronic disease. We're pleased to welcome him to *The Resonance Test.* In this energetic conversation, Brooks and Continuum SVP Mike Dunkley range all over the diabetes ecosystem, covering the move from a technological focus to more holistic solutions, how AI and machine learning might provide new opportunities, what future business models might look like, and in general, how we need to develop new approaches to diabetes. Tune in to hear Brooks say: • “I just have a strong passion to see what I can do to try and help the now 461 million people around the world that have diabetes.... We all look at the numbers. It's only escalating. We need to think differently.” • “All of the players need to be in the solution business.” • “Part of the problem is there hasn't been a lot of economics to reward helping people not develop a chronic condition.” • On doctors: “They've got 15 minutes to try to come up with something intelligible and if they're spending 10 minutes to try to get the bottom of it, that's not a good use of their time.” • “If the AI enables better understanding of what's going on with people with diabetes, the key is: How do the healthcare providers, nurse educators, clinicians, partner care doctors, endocrinologists, how do they adopt? Because, at the end of the day, their economics are important.” Host: Pete Chapin Editor: Kyp Pilalas Producer: Ken Gordon