Podcasts about biomimetic

Join Elevated GP: www.theelevatedgp.com Net32.com  Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram   Dr. Mandelaris attended the University of Michigan from undergraduate through dental school.  He completed a post-graduate residency program at the University of Louisville, School of Dentistry, where he obtained a certificate in the speciality of Periodontology as well as a Master of Science (M.S.) degree in Oral Biology.  Dr. Mandelaris is a Diplomate of the American Board of Periodontology and Dental Implant Surgery and has served as an examiner for Part II (oral examination) of the American Board of Periodontology's certification process. He is a Clinical Assistant Professor in the Department of Graduate Periodontics at the University of Illinois, College of Dentistry (Chicago, IL) and an Adjunct Clinical Assistant Professor at the University of Michigan, Department of Periodontics and Oral Medicine (Ann Arbor, MI).  Dr. Mandelaris is a Fellow in both the American and International College of Dentists. Dr. Mandelaris serves as an ad-hoc reviewer for the Journal of Periodontology and the International Journal of Oral and Maxillofacial Implants. In 2021, he was appointed as an Editorial Consultant to the International Journal of Periodontics and Restorative Dentistry. He has published over 40 scientific papers in peer-reviewed journals and has authored eight chapters in seven different textbooks used worldwide on subjects related to computer guided implantology, CT/CBCT diagnostics and surgically facilitated orthodontic therapy (SFOT). Dr Mandelaris is one of the recipients of the 2017 and the 2021 American Academy of Periodontology's (AAP) Clinical Research Award, an award given to the most outstanding scientific article with direct clinical relevance in Periodontics. A nationally recognized expert, he was appointed by AAP to co-chair the Best Evidence Consensus Workshop on the use of CBCT Imaging in Periodontics as well as co-author the academy's guidelines. In 2018, he was recognized with American Academy of Periodontology's Special Citation Award.  Dr. Mandelaris is the 2018 recipient of The Saul Schluger Memorial Award for Clinical Excellence in Diagnosis and Treatment Planning. Dr. Mandelaris currently serves on the American Academy of Periodontology Board of Trustees and has served as a Past President of the Illinois Society of Periodontists. He has served on several committees for the American Academy of Periodontology and is one of the AAPs recommended speakers on topics related to periodontics-orthodontics and imaging/implant surgery. He is a key-opinion leader for several industry leaders and holds memberships in many professional organizations, including the American Academy of Periodontology, Academy of Osseointegration, American Academy of Restorative Dentistry and the American Society of Bone and Mineral Research. Dr. Mandelaris is in private practice at Periodontal Medicine & Surgical Specialists, LLC. He limits his practice to Periodontology, Dental Implant Surgery, Bone Reconstruction and Tissue Engineering Surgery. He can be reached at 630.627.3930 or gmandelaris@periodontalmedicine.org.

Inspired by the power of fasting to enhance lifespan, co-founder Dr. Chris Rhodes spent years researching the human body's response to a 36 hour fast and how it could unlock our built-in longevity bio-programs.In 2022, the first ever prototypes of Mimio were made, third party certified, and clinically validated to recreate the effects of fasting, even during a meal.Just this past year, Mimio launched its' Daily Biomimetic Cell Care, helping people across the country harness the transformative power of their own biology to enhance their healthspan and live at their peak.SHOW NOTES:0:39 Welcome to the podcast!2:45 About Dr. Chris Rhodes'3:31 Welcome him to the show!4:24 What is a biomimetic?6:29 Benefits of fasting for health10:29 Who is Mimio for?12:19 How to access food freedom!14:14 Nutrient-repair signals15:32 Getting out of “metabolic chaos”16:25 Alternate-day fasting19:12 Fasting with Mimio vs not fasting22:03 Ingredients in Mimio28:05 Reducing biological age with Mimio30:25 *ALIGN MAT*32:15 New Study 35:08 Alternatives to GLP-1s42:45 Chris personal testing experiments44:10 Observing glucose when fasting45:54 AI & Insights from Function Health50:44 New bio-mimetics coming soon!56:41 His final piece of advice58:04 Where to find Dr. Chris & Mimio58:47 Thanks for tuning in!RESOURCES:Website: MimioHealth.comIG: @mimiohealthAlign Mat - code: biohackerbabes to save $250 Our Sponsors:* Check out Puori: https://Puori.com/BIOHACKERBABESSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

With the invention of new materials for restorative dentistry, new techniques for application were needed. Research in bonding to dentin showed bond strengths that approached the cohesive strength of a tooth, but getting this research into the hands of practicing dentists was another process entirely. As Dr. David Alleman was learning and researching new protocols in adhesive dentistry, his questions about why debonds occurred in select areas of the tooth led to his formulation of the concepts of the hierarchy of bondability and decoupling with time, all while creating his Six Lessons Approach to Biomimetic Restorative Dentistry. These new concepts that built on a foundation of dental research from the past four decades gave dentists anywhere the ability to bond predictably to deep dentin and restore the tooth in a way that mimicked the form and function of a natural tooth: biomimetic dentistry. Send us a textStudy with Dr. David Alleman in 2025:Biomimetic Mastership - class starts September 15. Learn more and register at allemancenter.com/mastershipIn-Person SLA Workshop Dates:October 24-25December 12-13Learn more and register at allemancenter.com/trainingInstagram @david.alleman.dds@davey_alleman_dmd@allemancenter.comYouTube@allemancenter

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsMaría J. Vicent : Polypeptide-Based Nanomedicines: Enhancing Tropism and Overcoming Biological BarriersMaría J. VicentProfesseur, CIPF ValenceRésuméPolypeptides play a crucial role in areas like nanomedicine, where their biological function is governed by intricate structural features. Studying structure-activity relationships is essential to optimize polypeptide-conjugate designs, as minor structural changes can lead to unexpected yet highly effective biological outcomes. We have addressed traditional synthetic limitations by using controlled NCA polymerization and rigorous characterization, producing well-defined architectures. Post-polymerization modifications introduce various functional groups and orthogonal reactive sites, enabling a wide range of polypeptide configurations, such as diblock copolymers and star-shaped structures. These can self-assemble into supramolecular nanostructures with unique biological properties, including tissue specificity, subcellular targeting, and potential brain delivery. Through a bottom-up strategy and the strategic design of polymer-drug linkers, in vitro and in vivo assessments have shown these systems to be non-toxic, with enhanced cellular uptake and extended half-life and accumulation in specific tissues like lymph nodes, mitochondria, and the brain. These findings position our polypeptide-based nanosystems as promising therapeutics.María J. VicentProfessor María J. Vicent leads the Polymer Therapeutics Lab at the Príncipe Felipe Research Center (CIPF) since 2006 and became its Scientific Director and Cancer Program Coordinator in 2024. She also oversees the Screening Platform, part of the EU-OpenScreen infrastructure, and currently serves as president-elect of the Controlled Release Society (CRS). Additionally, she is Editor-in-Chief of Advanced Drug Delivery Reviews. Her research focuses on designing innovative nanopharmaceuticals through Polymer Therapeutics to address unmet clinical needs in diagnostics and therapy. Her work has been supported by national and EU grants, including ERC-funded projects like MyNano, Polymmune, and Polybraint, as well as NanoPanTher and other public-private initiatives. María has received multiple accolades such as the Idea and Samyang awards and Women in Science honors. She is a Fellow of the National Academy of Inventors (FNAI), the AIMBE College of Fellows (since 2019), and the CRS College of Fellows (since 2021). With over 155 peer-reviewed publications and 15 patents, her innovations have led to six technology licenses, one of which helped launch the spin-off Polypeptide Therapeutic Solutions S.L. in 2012. The company, rebranded as Curapath after its acquisition by Arcline in 2021, is now a leading CDMO with over 100 employees.

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsSébastien Lecommandoux : Biohybrid and Dynamic Polymersomes: from Precision Therapy to Artificial CellsSébastien LecommandouxEnseignant-chercheur au Laboratoire de chimie des polymères organiques, Bordeaux INP, professeur invité du Collège de France

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsTimothy J. Deming : Enhancing biomimicry via polypeptide side-chain modificationsTimothy J. DemingProfesseur, UCLARésuméOur lab has pursued development of methods to allow selective incorporation of diverse functionality into synthetic polypeptide materials. Specifically, we have developed synthetic methods that allow a robust variety of modifications to nucleophilic thioether containing side-chains in both methionine and alkylated cysteine residues. Here we show such modifications can create synthetic polypeptides that can mimic environmentally responsive coacervate formation as has been observed in cytosolic proteins. We also show how modifications can be performed simultaneously on both segments of aqueous block copolymer assemblies resulting in materials that can respond to biologically relevant stimuli.Timothy J. DemingTimothy J. Deming received a B.S. in Chemistry from the University of California, Irvine in 1989, and graduated with a Ph.D. in Chemistry from the University of California, Berkeley, in 1993. After a NIH postdoctoral fellowship at the University of Massachusetts, Amherst with David Tirrell, he joined the faculty in the Materials Department at the University of California, Santa Barbara in 1995. Here he held appointments in the Materials and Chemistry Departments where he was promoted to Associate Professor in 1999 and Full Professor in 2003. His appointment is now as Distinguished Professor of Bioengineering and Chemistry and Biochemistry at the University of California Los Angeles. He served as the Chairman of the Bioengineering Department at UCLA from 2006 to 2011. He is a leader in the fields of polypeptide synthesis, self-assembly of block copolypeptides, and use of polypeptides in biology, for which he has received awards from the National Science Foundation, the Office of Naval Research, The Arnold and Mabel Beckman Foundation, the Alfred P. Sloan Foundation, the Camille and Henry Dreyfus Foundation, the Materials Research Society, and the IUPAC Macromolecular Division. He is also a Fellow of the American Institute of Medical and Biological Engineering, and recently received the Fulbright-Tocqueville Distinguished Chair Award. Professor Deming has a long track record of training students for performing ethical, rigorous research and for organizing their data for presentations and publications. He is active in the bioinspired materials community, recently served as an Associate Editor for Biomacromolecules, and has been an Editorial Advisory Board member for Macromolecular Bioscience, Soft Matter, Macromolecules, and Biopolymers.

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsRaffaele Mezzenga : Amyloid-metal biohybrids for health and environmental remediationRaffaele MezzengaProfesseur, ETH ZurichRésuméAmyloid fibrils interact with metal ions via metal-ligand supramolecular interactions whose energy is of the order of tens to hundreds of KBT. The occurrence of the 20 essential amino acids in food-based amyloid fibrils derived from inexpensive animal and plant proteins, including from food waste, combined with the extreme aspect ratio of the amyloids, allow for an affordable, yet universal toolbox to produce multifunctional hybrids which can serve in a multitude of applications and technologies. In this talk I will provide several examples of food amyloid fibrils interacting with metal ions and nanoparticles for both health and environmental remediation, some of which have made it into real technologies. Taking β-lactoglobulin amyloids as a model amyloid system derived from whey, a by-product of cheese making process, I will show how metal ions can be adsorbed from water and wastewater solutions by amyloid-based filters for water purification purposes, or how gold ions can be adsorbed and processed from amyloid aerogels to recycle gold from e-waste. I will also show how iron atoms can be coordinated to β-lactoglobulin amyloids to deliver highly bioavailable Fe(II) for iron fortification, or to design hydrogels capable of performing cascade enzymatic reactions for alcohol detoxification in vivo. Raffaele MezzengaRaffaele Mezzenga is full professor at ETH Zurich since 2009. His research focuses on the self-assembly of proteins, polymers, liquid crystals, food and colloidal systems. He is a Highly Cited Researcher (Clarivate, 2023) in the cross-field discipline, with more than 450 publications and 20 patents. His work has been recognized by several prestigious international distinctions such as the 2017 Fellowship and the 2013 Dillon Medal by the American Physical Society, the 2013 Biomacromolecules/Macromolecules Young Investigator Award by the American Chemical Society, the 2011 American Oil Chemists' Society Young Scientist Research Award, and the 2004 Swiss Science National Foundation Professorship Award.

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsMolly Stevens : Designing and translating new materials for advanced therapies and disease detectionMolly StevensJohn Black Professor of Bionanoscience, University of OxfordRésuméThis talk will present recent advances in therapeutic and biosensing materials, with a focus on translational pipelines for clinical application. We have developed scalable fabrication methods to create complex 3D architectures and biofunctionalized surfaces with spatially organized biochemical and topographical cues. Our delivery platforms include high-molecular-weight polymer carriers for saRNA therapeutics and photo-responsive nanoreactors inspired by circadian rhythms. We are also exploring bioinspired soft robotics for targeted, stimuli-responsive drug delivery.In diagnostics, we are engineering functionalized nanoparticles for in vivo disease detection, including colorimetric nanoprobes for visual readouts and CRISPR-based, preamplification-free RNA detection (CrisprZyme). We have developed Raman microspectroscopy tools and machine learning techniques for hyperspectral unmixing, enabling the analysis of live-cell and organoid models and tracking nanomedicines in vivo.A key innovation is our SPARTA™ platform, which enables high-throughput, label-free characterization of single nanoparticles, supporting the development of nanoparticle therapeutics and exosome diagnostics.This talk will explore how these technologies are advancing biomedical innovation and how we are establishing translational pathways to bring them into the clinic—while striving to make healthcare solutions more accessible and equitable. Molly StevensProfessor Dame Molly Stevens FREng FRS is John Black Professor of Bionanoscience at the University of Oxford (Department of Physiology, Anatomy and Genetics and Institute of Biomedical Engineering) and part-time Professor at Imperial College London and the Karolinska Institute. Professor Stevens' multidisciplinary research balances the investigation of fundamental science with the development of technologies and designer biomaterials to address some of the major healthcare challenges across diagnostics, advanced therapeutics and regenerative medicine. The impact of her work is recognised by numerous accolades, including the 2023 Novonordisk Prize. Professor Stevens' work has a strong translational drive, focussed on translating scientific innovation into practical solutions to benefit patients and society. She is a serial entrepreneur and the founder of four spin-off companies in the diagnostics, advanced therapeutics, and regenerative medicine space. She has been recently appointed as Oxford University Champion for Women and Diversity in Entrepreneurships.

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsSam Stupp : Role of Supramolecular Motion in Cell SignalingSam StuppProfesseur, Northwestern UniversitySam StuppSamuel Stupp is Board of Trustees Professor of Materials Science and Engineering, Chemistry, Medicine, and Biomedical Engineering at Northwestern University. He also directs Northwestern's Center for Regenerative Nanomedicine. Stupp's interdisciplinary research is focused on developing self-assembling supramolecular nanostructures and materials for functions relevant to renewable energy, regenerative medicine, and robotic soft matter. He is a member of the U.S. National Academy of Sciences, the U.S. National Academy of Engineering, the American Academy of Arts and Sciences, the Royal Spanish Academy, the National Academy of Sciences of Latin America, the National Academy of Sciences of Costa Rica, and the U.S. National Academy of Inventors. Stupp has won numerous awards over the course of his career, including three American Chemical Society national awards: the Award in Polymer Chemistry, the Ronald Breslow Award for Achievement in Biomimetic Chemistry, and the Ralph F. Hirschmann Award in Peptide Chemistry. He recently received the 2022 Materials Research Society Von Hippel Award, the highest honor awarded by this society. Other awards include the Department of Energy Prize for Outstanding Scientific Accomplishment in Materials Chemistry, the Materials Research Society Medal Award, the Royal Society of Chemistry Award in Soft Matter and Biophysical Chemistry, and the Nanoscience Prize from the International Society for Nanoscale Science, Computation, and Engineering, which recognizes lifelong achievement in the field.

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsKazunori Kataoka : Self-Assembling Polymer Nanosystems: Towards Clinical Translation of Smart Drug DeliveryKazunori KataokaProfesseur, iCONM - University of TokyoRésuméSelf-assembling polymer-based nanosystems, particularly polymer micelle-type drug delivery systems (PM-DDS), have emerged as powerful platforms for the smart delivery of therapeutic agents. Constructed through the spontaneous organization of precision-engineered block copolymers, these nanoscale carriers—typically 10 to 100 nm in size, comparable to viruses—feature a core–shell structure that enables both efficient drug encapsulation and excellent biocompatibility. While initially developed for small-molecule delivery, PM-DDS technology has rapidly evolved to accommodate more complex modalities such as nucleic acid and protein therapeutics, as well as imaging contrast agents. This presentation will focus on recent advances in PM-DDS, with particular emphasis on systems designed for the delivery of nucleic acid-based drugs including siRNA, antisense oligonucleotides (ASO), and mRNA. Highlighted examples include platforms that have progressed to clinical evaluation, underscoring the translational potential of these self-assembling nanocarriers in addressing intractable diseases.Kazunori KataokaProf. Kazunori Kataoka is the Center Director of the Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, and Professor Emeritus at the University of Tokyo. For over four decades, he has made pioneering contributions to the fields of biomaterials, particularly in drug delivery and targeting, non-viral gene delivery, and nanomedicine. He has authored more than 600 peer-reviewed publications, which have garnered over 100,000 citations (h-index: 168), and has been recognized as a Highly Cited Researcher by Clarivate Analytics for nine consecutive years since 2016. His many accolades include the Clemson Award from the Society for Biomaterials (2004), the Founder's Award from the Controlled Release Society (2006), the NIMS Award from the National Institute for Materials Science (Japan, 2009), the Humboldt Research Award (2012), the Leo Esaki Prize (2012), the Gutenberg Research Award (2015), the Princess Takamatsu Cancer Research Fund Prize (2017), the Biomaterials Global Impact Award (2023), and the Clarivate Citation Laureate in Chemistry (2023). He is an International Member of the U.S. National Academy of Engineering (since 2017), and a Fellow of the U.S. National Academy of Inventors (since 2017). In 2018, he was awarded the honorary degree Doctor Honoris Causa (Dr.h.c.) by Johannes Gutenberg University Mainz, Germany

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsPatrick Couvreur : Advanced nanomedicines for the treatment of severe diseasesPatrick CouvreurProfesseur invité, Collège de FranceRésuméEven if new molecules are discovered to treat severe diseases, the clinical efficacy of conventional chemotherapeutics is hampered by drug resistance and non-specific biodistribution. Advanced nanodevices may overcome some of these limitations. This will be illustrated by several advanced nanomedicine platforms: The design of biodegradable doxorubicin-loaded polyalkylcyanoacrylate nanoparticles for the treatment of the multidrug resistant hepatocarcinoma (a nanomedicine with phase III clinical trials ended).The construction of nanoparticles made of metal oxide frameworks (NanoMOFs), a highly hyperporous material obtained by the complexation of iron oxide clusters with diacids.The "squalenoylation", a technology that takes advantage of the squalene's dynamically folded molecular conformation, to link this natural and biocompatible lipid with drug molecules to achieve the spontaneous formation of nanoassemblies (100–300 nm). These squalene-based nanoparticles are using the circulating LDL as "indirect" carriers for targeting cancer cells with high expression of LDL receptors. The application of the "squalenoylation" concept to the treatment of cancer and neurological disorders will be discussed too.Patrick CouvreurPatrick Couvreur is a Professor Emeritus at Université Paris-Saclay and a member of the French Academy of Sciences. He held the Liliane Bettencourt Chair of Technological Innovation at the Collège de France in 2010 and is also a member of the Institut Universitaire de France (IUF). A world-renowned expert in drug delivery and nanomedicine, his research focuses on the use of nanotechnologies to develop targeted therapies for severe diseases, particularly cancer and central nervous system disorders. He has founded three start-ups, one of which was listed on the stock exchange and led the development of a nanomedicine that reached phase III clinical trials for the treatment of resistant hepatocellular carcinoma. Professor Couvreur is also a member of the French National Academy of Medicine, the Academy of Technologies, and served as President of the French Academy of Pharmacy in 2020. Internationally, he is a member of the U.S. National Academy of Medicine, the U.S. National Academy of Engineering, the Royal Academy of Medicine of Belgium, the Royal National Academy of Pharmacy in Spain, and the Japan Academy of Pharmaceutical Sciences and Technology. He has received numerous prestigious awards both in France and abroad, including the Host Madsen medal, the CNRS Innovation Medal, the Galien Prize, and the European Inventor Award.

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsHarm-Anton Klok : Surface-Grafted Polymer Brush Films: Leveraging Structural Complexity For New Properties and FunctionsHarm-Anton KlokProfesseur, EPFLRésuméSurface-initiated polymerization is a unique way to produce thin, functional polymer films. As polymer chains are grown from surfaces that are modified with initiators or chain transfer agents to mediate chain growth, this process ensures a unidirectional growth and net parallel alignment of the polymer tethers. These surface-grafted polymer brushes have a complex nanoscale structure that is characterized, amongst others, by a non-uniform segment density profile. This presentation will highlight 3 examples of surface-grafted polymer brushes with unique non-biofouling and lubrication characteristics, as well as piezo- and pyroelectric properties, which demonstrate the intricate relationship between nanoscale structure and properties for surface-grafted polymer brushes.Harm-Anton KlokHarm-Anton Klok is Full Professor at the Institutes of Materials, and Chemical Sciences and Engineering at the Ecole Polytechnique Fédérale de Lausanne (EPFL) (Lausanne, Switzerland). He studied chemical technology at the University of Twente (Enschede, The Netherlands) from 1989 to 1993 and received his Ph.D. in 1997 from the University of Ulm (Germany) after working with Martin Möller. After postdoctoral research with David N. Reinhoudt (University of Twente) and Samuel I. Stupp (University of Illinois at Urbana–Champaign, USA), he joined the Max Planck Institute for Polymer Research (Mainz, Germany) in early 1999 as a project leader in the group of Klaus Müllen. In March 2003 he joined EPFL.

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsJan van Hest : Polymer-based artificial cellsJan van HestProfesseur, Eindhoven University of TechnologyRésuméCompartmentalization is generally regarded as one of the key prerequisites for life. To better understand its role, there is a clear need for model systems in which life-like properties can be installed. In this lecture I will discuss a synthetic cell platform composed of a complex polymer coacervate formed from oppositely charged amylose derivatives and stabilized by a semi-permeable polymer membrane. The coacervate structure resembles better the crowded environment observed in the cytoplasm than vesicular structures normally do. Cargo, such as enzymes, can be highly effectively loaded in the coacervates, based on complementary charge and affinity. This allows protocell communication with this robust synthetic platform. Using natural scaffolding proteins we can controllably take up and release proteins from the artificial environment, which mimics natural secretion. We have reconstructed the cellular architecture of a eukaryotic cell by incorporating multiple artificial organelles, both with membrane-bound and membrane-less architectures. Furthermore we have equipped the cells with an artificial cytoskeleton that allows us to modulate membrane dynamics and mechanical properties. Finally, we are able to incorporate life-like features such as motility in these structures, making this class of artificial cells a very versatile platform to study and mimic biological processes.Jan van HestJan van Hest obtained his PhD from Eindhoven University of Technology in 1996 with prof E.W. Meijer. After a postdoctoral stay with prof D.A. Tirrell, he joined the chemical company DSM. In 2000, he was appointed full professor in Bio-organic chemistry at Radboud University Nijmegen. As of September 2016 he holds the chair of Bio-organic Chemistry at Eindhoven University of Technology. Since May 2017 he is the scientific director of the Institute for Complex Molecular Systems. He is one of the main applicants of two gravitation programs on Functional Molecular Systems and Interactive Polymer Materials, and was awarded two ERC Advanced grants (2015 and 2024). He has been elected member of the Royal Netherlands Academy of Arts and Sciences in 2019, the Academia Europaea in 2023 and was awarded the Spinoza premium in 2020. 65 PhD students have obtained their doctorate degree under his supervision, and he has published around 400 papers. He is also cofounder of four start-up companies. The group's focus is to develop well-defined compartments for nanomedicine and artificial cell research. Using a combination of techniques from polymer science to protein engineering, well-defined carriers and scaffolds are developed for application in cancer treatment and immunology.

Sébastien LecommandouxCollège de FranceInnovation technologique Liliane Bettencourt (2024-2025)Année 2024-2025Colloque - Advancing Biomaterials: Biomimetic and Biohybrid InnovationsWelcome and IntroductionSébastien LecommandouxEnseignant-chercheur au Laboratoire de chimie des polymères organiques, Bordeaux INP, professeur invité du Collège de FrancePrésentationLe colloque se concentrera sur les innovations de pointe en matière de biomatériaux, avec un focus sur les organelles synthétiques fonctionnelles et les (bio)matériaux biomimétiques. Ces matériaux, inspirés par les systèmes naturels, sont conçus pour reproduire et améliorer les fonctions biologiques dans des applications médicales avancées. Un aspect central des discussions portera sur les auto-assemblages supramoléculaires multi-échelle et multi-composants, des structures dynamiques capables de s'organiser spontanément, avec des implications directes pour la médecine régénérative, les systèmes de délivrance de médicaments ou à plus long terme dans les neurosciences.Les sessions exploreront également la nanotechnologie moléculaire biomimétique, une approche qui utilise des stratégies inspirées par la nature pour concevoir des systèmes à l'échelle nanométrique capables de répondre aux défis thérapeutiques. Le rôle des polymères thérapeutiques sera mis en avant, avec une attention particulière aux polypeptides bioinspirés, qui, grâce à leur versatilité et leur biocompatibilité, dont énormes et récents progrès ouvrent de nouvelles perspectives.Le colloque traitera également des systèmes biohybrides à base de protéines, fusionnant des composants biologiques et synthétiques pour créer des matériaux multifonctionnels. Ces systèmes, intégrant des mécanismes du vivant et des matériaux artificiels, offrent des perspectives uniques pour développer des solutions thérapeutiques innovantes, notamment en immunothérapie et en oncologie. Ce rendez-vous scientifique mettra en lumière les intersections entre biologie et chimie des matériaux, et leur potentiel pour transformer la médecine moderne.

In this podcast episode, MRS Bulletin's Laura Leay interviews Fabian Meder from the Italian Institute of Technology in Genova and the Sant'Anna School of Advanced Studies in Piza, Italy about his research group's device that makes use of wind-driven plant leaf motion to generate electricity which can power a chemical delivery system. Their triboelectric nanogenerator involves an artificial leaf made of a 500 μm silicone elastomer layer and an electrode made from indium tin oxide. This is attached to the leaf of a plant. A gold-coated pin electrode inserted in the stem of the plant harvests charges from the plant tissue. This work was published in a recent issue of Bioinspiration & Biomimetic. 

Biomimetic dentistry can be defined by three main principles: preserve pulp vitality, conserve critical tooth structure and fully connect the tooth at 30 MPa or more. Mimicking nature (biomimetic) is about scientific analysis of how natural teeth function and replicating those principles during the restorative process. This isn't art; this is science. In this episode Dr. David Alleman discusses the research behind understanding how a natural tooth functions and how practitioners can replicate that to improve clinical outcomes with biomimetic restorative dentistry.Article referenced in this episodeWang RZ, Weiner S. Stain-structure relations in human teeth using Moire fringes. J of Biomechanics. 1998;31:135-141.Alleman D, Magne P, A systematic approach to deep caries removal endpoints PSZ. Quintessence Intl. 2012;43(3):197-208.Send us a textNew 2025 training programs announced:Biomimetic Mastership - class starts February 10. Learn more and register at allemancenter.com/mastershipIn-Person SLA Workshop Dates:April 25-26August 8-9October 24-25December 12-13Learn more and register at allemancenter.com/trainingLearn more about Dr. Alleman's work at training programs at allemancenter.com.Instagram @david.alleman.dds@davey_alleman_dmd@allemancenter.comYouTube@allemancenter

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826241296675

Biomimetic restorative dentistry has been taught and practiced for over 20 years, with its roots linked to minimally invasive dentistry that started decades earlier. Minimally invasive dentistry sought to conserve tooth structure and restore only parts of the tooth affected by pathologies. With the invention of adhesive materials, adhesive dentistry showed promise in advancing minimally invasive principles with new materials that no longer required retention, but the adhesive restorations still fell short. Teeth are more complex than many other materials that are adhesively connected, so simply bonding the restoration to the tooth did not yield long-term success.In this episode Dr. David Alleman discusses how minimally invasive dentistry paved the way for the more conservative approaches we use today, how biomimetic dentistry made adhesives more predictable, allowing for longer-lasting bonds, and where cosmetic dentistry fits in to the adhesive dentistry spectrum.Send us a textNew 2025 training programs announced:Biomimetic Mastership - class starts February 10. Learn more and register at allemancenter.com/mastershipIn-Person SLA Workshop Dates:April 25-26August 8-9October 24-25December 12-13Learn more and register at allemancenter.com/trainingLearn more about Dr. Alleman's work at training programs at allemancenter.com.Instagram @david.alleman.dds@davey_alleman_dmd@allemancenter.comYouTube@allemancenter

Join Elevated GP: www.theelevatedgp.com DOT - Use the Code DENTALDIGEST for 10% off Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin   Joe Oxman received his Ph.D. in organic photochemistry from Northwestern University (1983). He has been employed by 3M for 38 years and is currently a corporate scientist. He is a developer of many dental and non-dental technologies and is considered a global expert in photocurable systems, nanotechnology, structural composites, hard tissue adhesives, glass ionomer materials, orthogonal smart-materials, bioactives, and technologies to minimize polymerization shrinkage stress. He has 115 issued U.S. patents, more than 100 publications/abstracts in peer-reviewed journals, and has been an invited global lecturer for more than 350 keynotes, presentations, and dental school curricula. He has received many international recognitions, including induction into the prestigious 3M Carlton Society (2003), two American Chemical Society (ACS) Cooperative Research Awards (2007 and 2020), the University of Colorado Engineering & Applied Science Corporate Advocate Award (2007), the IADR Peyton Skinner Award for Innovation in Dental Materials (2013), ACS Industrial Polymer Science Award (2016), and induction as an ACS Polymer Fellow (2017). He was instrumental in co-establishing the NSF Cooperative Research Center on “Fundamentals & Applications of Photopolymerization” (Universities of Iowa and Colorado). He currently serves on the Board of Directors of AADOCR, the MinnCResT External Review Board, and previously served as the 3M Director of Research for the University of Minnesota Dental Research Center for Biomaterials and Biomechanics and as a coach and judge for the Discovery Education/3M Young Scientist Challenge. 

Join Journal Club Download my free guide to Internal Bleaching PDF Follow @dental_digest_podcast Instagram Connect on Instagram: @dr.melissa_seibert on Instagram DOT - Use the Code DENTALDIGEST for 10% off Dr. Walter Renne is the founder of the MOD Institute and leads all learning, innovation and research initiatives at the organization. He is a recognized global key opinion leader for renowned dental technology companies including Planmeca and Ivoclar Vivadent. He also previously served as a Professor and Assistant Dean of Innovation and Digital Dentistry at the Medical University of South Carolina. As the assistant director for the digital dentistry residency program, he has won several national and regional awards for his efforts both pre-clinically and clinically. He is also an active dental researcher and has published over 30 studies on scan and milling accuracy using various systems. Dr. Renne also has several patents including a patent for a platform of long-term antimicrobial dental materials.

Real talk with Dr. Jennifer Haddad (@drjenniferhaddad) about who and what influenced her dental career, including learning from one of the leaders of biomimetic dentistry, Dr. Pascal Magne (@pascal_magne). She also defines the "5 year rule" in dentistry, aka professional growing pains and how to deal with them. To learn more about Dr. Jennifer Haddad or to connect with her, check out these links: Website Instagram If you want to join the conversation about the realities of dentistry, follow me on: Instagram: ⁠⁠@_teethmatter⁠⁠ LinkedIn: ⁠⁠Ellie Halabian⁠⁠ __________________________ If you enjoy the podcast, subscribe and rate ⭐️.If you think a friend will enjoy it, please share it with them. --- Support this podcast: https://podcasters.spotify.com/pod/show/teethmatters/support

Dr. David Alleman first created his Six Lessons Approach for vital teeth, but the same conservative principles can benefit endodontically treated teeth too. Compared to traditional techniques for retention and bonding, the advanced adhesive and stress-reducing techniques of biomimetic dentistry are better suited for treating non-vital teeth, which are more brittle and susceptible to cracking than fully hydrated teeth with healthy pulps. This episode outlines how biomimetic techniques approach endodontically treated teeth differently and the research that supports these protocols.Articles referenced in this episode:Kishen A., Vedantam S. Hydromechanics in dentine: Role of dentinal tubules and hydrostatic pressure on mechanical stress-strain distribution. Dent Materials. 2003;23: 1296-1306Magne  P,  Belser  U. Rationalization of Shape and Related Stress Distribution in Posterior Teeth A finite Element Study Using Nonlinear contact Analysis. J Periodontics Restorative Dent. 2002;22-425-433Jayasooriya  PR,  Pereira  PNR,  Nikaido  T,  Tagami  J. Efficacy of a Resin Coating on Bond Strengths of Resin Cement to Dentin. J Esthet Restor Dent 2003 15(2)105-113Fennis  WMM,  Kuijs  RH,  Kreulen  CM,  Verdonschot  N,  Creugers  NHJ. Fatigue Resistance of Teeth Restored with Cuspal-Coverage Composite Restorations. Int J Prosthodont 2004 17(3)-313-317Send us a textLearn more about Dr. Alleman's work at training programs at allemancenter.com.Instagram @david.alleman.dds@davey_alleman_dmd@allemancenter.comYouTube@allemancenter

Daily dentistry, the cases you see every day, usually involves minor occlusal adjustments that can be treated quickly and predictably using the Six Lessons Approach, but biomimetic techniques can benefit more advanced occlusal cases too. In this episode, Dr. David Alleman discusses the cause of abfractions, how complex temporaries are a thing of the past and options for doctors seeking more advanced occlusal training beyond everyday cases.Articles referenced in this episode:Magne P,  Belser  U. Rationalization of Shape and Related Stress Distribution in Posterior Teeth A finite Element Study Using Nonlinear contact Analysis. J Periodontics Restorative Dent. 2002;22-425-433Pintado M, Et al. Variation in tooth wear in young adults over a two-year period. J Prosth Dent. 1997(77)3. 313-320.Send us a textLearn more about Dr. Alleman's work at training programs at allemancenter.com.Instagram @david.alleman.dds@davey_alleman_dmd@allemancenter.comYouTube@allemancenter

What if your dental fillings could last longer and preserve more of your natural tooth? Join us as we explore the cutting-edge world of biomimetic dentistry with esteemed guests Dr. Isabel Perez and Dr. Jeanette Carroll. I'm Dr. Rebecca Taylor, and together, we uncover how this innovative approach not only mimics the natural structure of teeth but also addresses the limitations of traditional dental methods. We highlight how biomimetic techniques can prevent micro fractures and improve the longevity of your restorations, ensuring a healthier, more durable smile.Imagine a dental treatment that reduces sensitivity, minimizes bacterial infiltration, and significantly lowers the likelihood of future dental work. This episode takes a deep look at the advantages of biomimetic dentistry over traditional methods, such as amalgam and composite fillings. We share advanced bonding techniques that combat common issues like shrinkage and gaps, which often lead to discomfort and further complications. Plus, we discuss the benefits of indirect restorations fabricated in a lab, which offer superior strength and reliability.Why sacrifice healthy tooth structure for the sake of restoration? We delve into how preserving natural tooth material can extend the life of your teeth and lessen the need for invasive procedures like crowns and root canals. Traditional methods often result in subgingival margins and leftover cement, causing inflammation and periodontal problems. Biomimetic dentistry keeps margins above the gum line, promoting better oral health. Tune in to discover how Green City Dental's integration of biomimetic principles can revolutionize your dental care experience.

Biomimetic dentistry aims to mimic a natural tooth throughout the restorative process. The last four decades of research has shown that mimicking and conserving a tooth's natural connection to itself, its natural bond and resilience to occlusal forces and its natural defense mechanisms for infection benefits the tooth's long-term health. This is also true for occlusion.In this episode, Dr. David Alleman discusses what all dentists can learn from a body's natural occlusion, lost research from the last few decades and approaches for daily occlusal techniques that can be applied to cases doctors regularly see in their office.Articles referenced in this episode:Michael C. Alpern. The Ortho Evolution: The Science and Principles Behind Fixed/Functional/Splint Orthodontics. editor GAC International, Inc; 2003.Send us a textLearn more about Dr. Alleman's work at training programs at allemancenter.com.Instagram @david.alleman.dds@davey_alleman_dmd@allemancenter.comYouTube@allemancenter

During a global pandemic, Dr. Vincent Buscemi was done. After years of traditional dentistry—graduating from dental school and building his practice—he found himself at a turning point. He was frustrated with the level of care he could offer his patients and knew he needed a change. When the pandemic gave him some unexpected downtime, Dr. Buscemi took the opportunity to explore new possibilities. What he discovered transformed not only his career but also the lives of his patients as he ventured into the world of biomimetic and holistic dentistry. Join Dr. Clayton as he and Dr. Buscemi dive into their personal journeys in disrupting the dental industry and finding their passion in both biomimetic dentistry and in holistic/functional dentistry. Get a behind-the-scenes look at how two holistic-minded dentists talk about the research on touchy subjects like orthodontics for young kids, oil pulling, and dental insurance. They'll share tips on how to find a dentist who shares their biomimetic and holistic approach, and when it might actually be okay to stick with your current provider. This conversation is packed with insights and real talk you won't want to miss! If you'd like to learn more about how to partner with the right provider based on your needs, check out our Functional Dentistry Roadmap. Links to books mentioned: "Jaws" - Sandra Kahn "Breath" - James Nestor Dr. Vincent Buscemi owns Buscemi Family Dentistry located near Detroit, Michigan if you are located near there! Make sure to follow us on Instagram at @restoration.dentistry for more disruptive dental education.

How can we help people with prosthetic legs walk more easily and with less effort? In this episode of Neurocareers: Doing the Impossible!, we explore this question with Giacomo Valle, PhD, a leading researcher in the field of biomimetic brain-computer interfaces (BCIs) and bionic legs. Dr. Valle and his colleagues at ETH Zürich have developed an innovative biomimetic BCI that uses peripheral nerve stimulation to convey naturalistic touch sensations in bionic legs. This groundbreaking work has earned them a spot as one of the 12 finalists for the BCI Award 2023. Dr. Valle's research focuses on creating artificial communication with the brain through peripheral nerve stimulation, providing a more intuitive and natural sensory experience. His team developed a biomimetic neurostimulation framework inspired by nature, capable of "writing" physiologically plausible information back into the peripheral nervous system. Using an in-silico model of mechanoreceptors, they created biomimetic stimulation policies, which were tested alongside mechanical touch and common linear neuromodulations. In clinical trials, these techniques have shown significant improvements in mobility and reduced mental effort compared to traditional approaches. The neural responses produced by this innovative approach resemble those naturally induced, marking a significant advancement in assistive neurotechnologies. Dr. Valle's project, "Biomimetic BCI Conveys Naturalistic Touch Sensations via Peripheral Nerve Stimulation for Bionic Legs," represents a major leap forward in neuroengineering and bionics. With an educational background that includes a B.S. in Biomedical Engineering and an M.S. in Bioengineering from the University of Genoa, and a Ph.D. in Biorobotics from the Scuola Superiore Sant'Anna, Dr. Valle has extensive experience in this field. His career journey includes research positions at the École Polytechnique Fédérale de Lausanne and ETH Zurich, where he contributed to significant innovations in neuroprosthetics. As a co-founder of the medtech startup MYNERVA and now a Tenure-track Assistant Professor in Bionics at Chalmers University of Technology in Sweden, Dr. Valle's research focuses on neuroengineering and computational models aimed at restoring sensory feedback and understanding somatosensory processing and neural control of movements. Join us as Dr. Valle shares insights into his research, discusses his career path, and offers valuable advice for a successful BCI Award submission. Whether you're interested in the latest advancements in neuroengineering or seeking inspiration for your own scientific endeavors, this episode is packed with fascinating insights and expert guidance. About the Podcast Guest: Dr. Giacomo Valle holds  a position as an Assistant Professor in Bionics, Head of the Neural Bionics Laboratory at the Department of Electrical Engineering  | Life Bionics Chalmers University of Technology in Hörsalsvägen 11, SE - 412 96, Gothenburg, Sweden Sahlgrenska Universitetssjukhuset R-huset, plan 7, Länsmansgatan 28, 431 80 Mölndal Other Dr. Valle's affiliations: Cortical Bionics Research Group, USA: https://www.corticalbionics.com/ Co-founder MYNERVA  Wyss Zurich Translational Center | ETH Zurich, Weinbergstrasse 35, WEH 8092 Zurich Switzerland Contact Information: E-mail: valleg@chalmers.se  @NeuralBionicsLab socials: LinkedIn, X.   Open Positions: The Neural Bionics Lab (PI: Giacomo Valle) has available projects (6-12 months) starting this fall and next spring on: - Bidirectional neuroprosthetics - Implantable Brain-Computer Interfaces - Somatosensation & Touch - Neural stimulation for sensory restoration - Cortical & peripheral interfacing - Mechatronics for neurotechnology - Human neurophysiology Please contact us here or at valleg@chalmers.se sending your CV, transcript of records (Bachelor and Master) and motivation letter. Info about the projects on https://sirop.org/app/ Our projects are done in collaboration with Biological Sciences Division at the University of Chicago, CBRG, University of Zurich and MYNERVA. hashtag About the Podcast Host: The Neurocareers podcast is brought to you by The Institute of Neuroapproaches (https://www.neuroapproaches.org/) and its founder, Milena Korostenskaja, Ph.D. (Dr. K), a neuroscience educator, research consultant, and career coach for people in neuroscience and neurotechnologies. As a professional coach with a background in the field, Dr. K understands the unique challenges and opportunities job applicants face in this field and can provide personalized coaching and support to help you succeed. Here's what you'll get with one-on-one coaching sessions from Dr. K: Identification and pursuit of career goals Guidance on job search strategies, resume, and cover letter development Neurotech / neuroscience job interview preparation and practice Networking strategies to connect with professionals in the field of neuroscience and neurotechnologies Ongoing support and guidance to help you stay on track and achieve your goals You can always schedule a free neurocareer consultation/coaching session with Dr. K at https://neuroapproaches.as.me/free-neurocareer-consultation Subscribe to our Nerocareers Newsletter to stay on top of all our cool neurocareers news at updates https://www.neuroapproaches.org/neurocareers-news

Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin  DOT - Use the Code DENTALDIGEST for 10% off Dr. Robert Stanley has been interested in dentistry since spending hours in his grandfather's dental office in Chicago as a child. After his grandfather passed away, Dr. Stanley became interested in Engineering and pursued his Masters and Ph.D. in the field. He worked at Sony Ericsson in Research Triangle Park as a Senior Project Manager. Since meeting his wife, Dr. Bobbi Stanley, and being involved with the growing dental practice, Dr. Robert Stanley realized that he still loved dentistry. He obtained a DDS from the University of North Carolina and joined his wife in practice. Robert Stanley's dental acumen is a perfect complement to the practice and distinguishes Stanley Dentistry from other general dentistry practices by offering comprehensive dentistry such as oral surgery, root canals, wisdom teeth removal, and full-mouth reconstruction with dental implants. Dr. Robert Stanley is an Adjunct Professor in the Prosthodontics Department at the University of North Carolina at Chapel Hill School of Dentistry and Co-founder and Senior Instructor at Stanley Institute for Comprehensive Dentistry. Dr. Robert Stanley is a Diplomate with the American Board of Oral Implantology (ABOI), a Diplomate with the International College of Oral Implantologists (ICOI), certified in Oral, IV, and Conscious Sedation and is a member of the Academy of General Dentistry, the American Academy of Cosmetic Dentistry (AACD), the American Dental Association (ADA), the Raleigh-Wake Dental Society, the North Carolina Dental Society, the Dental Organization for Conscious Sedation (DOCS) and the International Association of Comprehensive Aesthetics. In addition, Dr. Stanley is a Smile Engineer, offering his unique background in mechanical engineering and dentistry to companies around the world as a professional consultant in biomedical engineering. Dr. Stanley is available for professional collaboration for companies to make recommendations and changes to new or existing biomedically engineered products or services. ‍

https://www.robbinsdds.com/ https://www.mystoneoakdental.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin  DOT - Use the Code DENTALDIGEST for 10% off   J. William Robbins, D.D.S., MA., maintains a full-time private practice and is an Adjunct Clinical Professor in the Department of Comprehensive Dentistry at the University of Texas Health Science Center at San Antonio Dental School. He graduated from the University of Tennessee Dental School in 1973. He completed a rotating internship at the Veterans Administration Hospital in Leavenworth, Kansas and a 2-year General Practice Residency at the V.A. Hospital in  San Diego, California. Dr. Robbins has published over 80 articles, abstracts, and chapters on a wide range of dental subjects and has lectured in the United States, Canada, Mexico, South American, Europe, Middle East and Africa. He co-authored a textbook, Fundamentals of Operative Dentistry – A Contemporary Approach, which is published by Quintessence, and is in its 4th edition. He recently co-authored a new textbook, Global Diagnosis – A New Vision of Dental Diagnosis and Treatment Planning, which is also published by Quintessence. He has won several awards including the Presidential Teaching Award at the University of Texas Health Science Center, the 2002 Texas Dentist of the Year Award, the 2003 Honorary Thaddeus V. Weclew Fellowship Award from the Academy of General Dentistry, the 2010 Saul Schluger Award given by the Seattle Study Club, the Southwest Academy of Restorative Dentistry 2015 President's Award, and the 2016 Academy of Operative Dentistry Award of Excellence. He is a diplomat of the American Board of General Dentistry. He is past president of the American Board of General Dentistry, the Academy of Operative Dentistry, the Southwest Academy of Restorative Dentistry, and the American Academy of Restorative Dentistry.

I am a highly experienced holistic dentist with a professional journey spanning over three decades among disciplines and continents. My clinical practice, based in both the U.S. and Europe, encompasses general dentistry, systemic dentistry, cosmetic enhancements, preventive care, and specialized treatments such as amalgam removal, infection treatment, and snoring/sleep apnea interventions. I have had the privilege of leading dental departments, directing operations, creating dental technologies and patents, and overseeing patient care in diverse settings from private practices to specialized medical centers.    My commitment to holistic health extends beyond traditional dentistry; I've pursued advanced studies in aesthetic medicine, acupuncture, electro-acupuncture, and other integrative disciplines, furthering my understanding of the interconnectedness of oral health with overall wellbeing. My academic credentials include an MSc in Aesthetic Medicine from Queen Mary University of London, a Doctor of Dental Surgery Degree from the University of the Pacific, School of Dentistry, and a deep foundation in biochemistry from both California State University and UCLA.    As a staunch advocate for holistic, biomimetic, and environmentally conscious dentistry, I've acquired numerous accreditations, notably from the International Academy of Oral Medicine and Toxicology (IAOMT), Academy of Biomimetic Dentistry, and American Academy of Cosmetic Dentistry. Furthermore, my unique expertise in forensic dentistry as a Police Surgeon in New York showcases the diversity of my skills and contributions to the dental field.    Throughout my career, I have maintained active memberships with globally recognized dental associations, remaining committed to ongoing education, knowledge sharing, and promoting holistic dentistry principles. As a seasoned practitioner, I'm passionate about harnessing the power of integrative care to create personalized and comprehensive dental experiences for my patients.    Over the years, a consistent dedication to holistic dentistry has been showcased through diverse professional engagements, from the Holistic Dental Association's emphasis on Dental Epigenetics and Biomimetics to collaborations with Dr. Klinghardt Institute on systemic dentistry. This journey, marked by insights into the links between oral health and systemic well-being, has positioned dentistry as central to overall health. Both live sessions and online appearances, like the Myers Detox Podcast and Dr. Talks Summit, have echoed this sentiment, spotlighting the evolving role of dental practices in holistic wellness. I'm most proud of my patent established on United Stats Patient, Registered September 8th, 2020 for the Casanova Facelift technology.    I possess a wealth of expertise in dentistry and related fields, gained through extensive continuous education and specialized training that is unmatched except by the 1% of top dentists. My journey encompasses a diverse range of courses, seminars, and conferences, spanning topics such as advanced aesthetics, injectable fillers, dental implants, holistic dentistry, and more. Through this journey, I've developed a deep understanding of dental practice, blending theoretical knowledge with hands-on experience to embrace emerging technologies and evolving medical trends. Website : www.systemicdentist.com     Work With Me: Mineral Balancing HTMA Consultation: https://www.integrativethoughts.com/category/all-products  My Instagram: @integrativematt My Website: Integrativethoughts.com   Advertisements:   Valence Nutraceuticals: Use code ITP20 for 20% off https://valencenutraceuticals.myshopify.com/   Zeolite Labs Zeocharge: Use Code ITP for 10% off https://www.zeolitelabs.com/product-page/zeocharge?ref=ITP Magnesium Breakthrough: Use Code integrativethoughts10 for 10% OFF https://bioptimizers.com/shop/products/magnesium-breakthrough Just Thrive: Use Code ITP15 for 15% off https://justthrivehealth.com/discount/ITP15 Therasage: Use Code Coffman10 for 10% off https://www.therasage.com/discount/COFFMAN10?rfsn=6763480.4aed7f&utm_source=refersion&utm_medium=affiliate&utm_campaign=6763480.4aed7f   Chapters:   00:00 Introduction and Background 08:15 The Influence of Dr. Klinghardt 29:57 Preparation and Protocols for Dental Procedures 38:30 Understanding Cavitations and Their Impact on Health 54:46 The Importance of Holistic Healing in Addressing Cavitations 01:07:43 Diagnosing Cavitations with 3D Cone Beam Scans 01:17:20 Zirconia Implants: A Better Alternative to Titanium   Takeaways:   Biological dentistry takes a holistic approach to dental health, considering the impact of dental issues on the immune system and overall well-being. Mercury fillings and dental infections can have long-term effects on health, including chronic issues and systemic toxicity. Proper preparation and protocols are essential before and after dental procedures to ensure successful outcomes and minimize the risk of complications. Biomimetic dentistry focuses on conserving as much natural tooth structure as possible and using advanced techniques to promote longevity and oral health. Addressing gut health and heavy metal detoxification are crucial aspects of dental care and overall wellness. Cavitations are infections in the jaw that can cause autoimmune issues and other health problems. Improper tooth extractions and other factors can lead to cavitations. Mercury fillings and heavy metal toxicity can contribute to cavitations and other health issues. Detoxification and chelation protocols should be approached with caution and under the guidance of a knowledgeable practitioner. Addressing the physical, energetic, mental, intuitive, and spiritual aspects of healing is important. A 3D cone beam scan is recommended for diagnosing cavitations. Finding a dentist with expertise in whole body dentistry is crucial. 3D scans are essential for identifying cavitations and should be a standard practice in dentistry. Continuing education is crucial for dentists to stay updated on new treatments and technologies. Mineral balancing plays a significant role in overall health and should be considered in patient care. Melatonin can aid in detoxification and improve sleep architecture. Zirconia implants are a better alternative to titanium implants due to their biocompatibility and ability to allow light to pass through. Addressing structural issues before dental procedures is important for long-term success. Collaboration between dentists and chiropractors can enhance treatment outcomes.   Keywords: biological dentistry, mercury fillings, dental infections, cavitations, holistic approach, immune system, dental toxins, dental procedures, biomimetic dentistry, gut health, heavy metal detoxification, root canals, cavitations, jaw infections, autoimmune issues, tooth extractions, mercury fillings, heavy metal toxicity, detoxification, chelation, holistic healing, 3D cone beam scan, whole body dentistry, cavitations, 3D scans, continuing education, mineral balancing, melatonin, zirconia implants, structural issues, collaboration

Pablos is joined by Rob Shepherd, who's working on robotics that could really help us make robots more naturally integrated.

I've gotten to spend a little bit of time with Rob Shepherd over the years. He's working on soft robotics and all the different kinds of materials advancements that could really help us make robots that are more naturally integrated into the world. Things like polymer colloidal suspensions as inks for 3d printers so they can fabricate microfluidic devices, synthesizing single micron to millimeter scale parts in glass and silicon and all kinds of other stuff, like tiny gears. Imagine if you were trying to make a micro machinery like Swiss watches, but smaller. That's the kind of stuff that he worked on in the past and researched, developing pneumatic actuators, different kinds of elastomers and things that could maybe give us a real kind of muscles for robots. Also developing the kinds of walking and undulating movements that you would want robots to do once they got beyond just being these kind of rigid jerky things that we have now. This also gets really interesting when you're trying to make fingers for robots, which I'm personally obsessed with. I think it is a kingpin that's going to enable robots to start going to all the places they haven't been able to. We've seen some real progress on that lately. Rob is a great guy, super humble, willing to share everything he knows, which is a lot. Rob is an associate professor at the Sibley School of Mechanical and Aerospace Engineering at Cornell university. We recorded this in Ojai, California in a In-n-out Burger, on a Friday night, when it was full of teenagers... So this is it also an exercise in using AI for noise canceling, post-facto. I know it won't be the cleanest recording you've ever heard, but I think it will be interesting to know that we ran the audio through a tool called AUDO, and AUDO is one of many. I don't have anything to do with them. I've talked to the founders few times. I think it's cool. There's probably other ones, I don't know what the best ones are, but I've been using AUDO, and it's able to do this remarkable job cutting out, like a hundred noisy teenagers, while Rob and I are just sitting there eating burgers, talking about robots. So hopefully you'll learn something from that as well... Important Links: Cornell University Organic Robotic Labs Llume Cornell Engineering Robotics and Autonomy Advanced Manufacturing and Materials About Rob Shepherd Rob Shepherd received his B.S. (2002) and Ph.D. (2010) in Material Science at the University of Illinois where his research focused on developing polymeric and colloidal suspensions as 'inks' for 3D printers. He also fabricated microfluidic devices to synthesize single micron to millimeter scale parts. Concurrently to performing this research, he received his M.B.A. (2009) at U of I and started a company, worked with several other startups, and gained significant experience with the details of market research, financials, accounting issues, and legal aspects of entrepreneurship. In 2010, he continued his education as a post-doctoral fellow at Harvard University in George Whitesides's research group in the Department of Chemistry and Chemical Biology. In this group, he developed pneumatic actuators in soft elastomers that took the form of a machine capable of moving in multiple gaits: walking and undulating. These actuators have also been used for low-cost manipulators, and in concert with a microfluidic system for biomimetic camouflage & display.

In this episode, we dive deep into the fascinating world of fasting with Dr. Chris Rhodes, the co-founder and CEO of Mimio Health. Dr. Rhodes shares insights into the transformative power of fasting and sheds light on the research behind calorie restriction, offering listeners a glimpse into the potential keys to a healthier and longer live. We also explore the concept of fasting mimicking, the breakdown of mTOR vs AMPK, and the powerful ingredients that make Mimio a unique and effective tool in the pursuit of health optimization.Dr. Chris Rhodes is the co-founder and CEO of Mimio Health. He has a PhD in nutrition and has always been fascinated by how we eat affects our health and longevity. Inspired by the power of fasting to enhance lifespan, he spent years researching the human body's response to a 36 hour fast and how it could unlock our built-in longevity bio-programs.Mimio is a biomimetic supplement, derived from bioidentical molecules to the most powerful metabolites produced by our own bodies during a prolonged 36-hour fast, clinically shown to support a wide range of health benefits including enhanced energy, mood, memory and cognition, metabolism, balance to dietary inflammation, and healthy aging.SHOW NOTES:0:53 Welcome to the show!1:44 Dr. Chris Rhodes' Bio2:45 Welcome him to the podcast!3:28 About Mimio4:03 Dr. Chris' background4:54 Fasting for Longevity & Healthspan6:4 Research on Caloric Restriction10:16 Why is mimicking fasting helpful?11:28 His experience with fasting14:44 Longevity & Social Connection14:39 mTOR vs AMPK17:00 Rapamycin: Mechanism of Action18:58 Hormetic Stress & AMP-Kinase20:45 Mimio's Ingredient Sourcing23:59 C.Elegans for Life Extension25:10 *Filter Optix*27:48 The Biomimetic Approach28:28 Mimio Key Ingredients30:47 Nicotinamide & NAD33:45 Dosing structure of Mimio36:30 *Magnesium Breakthrough*38:18 What is Spermidine?43:18 OEA (Oleic Acid)45:29 Optimal duration for fasting47:55 PEA Fatty Acids52:18 Biological Age Testing54:29 Best practices for Mimio57:01 His final piece of advice59:55 Thanks for tuning in!RESOURCES:Website: www.MimioHealth.com - Save 20% with code BHBABES20IG: @mimiohealthIG: @thatnutritiondrFilter Optix Blue-Blocking Glasses: filterpoptix.com/biohackerbabes - code: BIOHACKERBABES to save 15% offMagnesium Breakthrough: Bioptimizers.com/biohackerbabes - code: biohackerbabes10Support this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

In this insightful segment, Paul O'Malley, D.D.S., a well-established figure in the world of biomimetic dentistry, sheds light on the nuanced approaches to modern dental care, including the potential advantages of biomimetic procedures over traditional methods. Discussing topics ranging from root canals to the use of dental lasers and the proper ways to identify genuine biomimetic practices, Dr. O'Malley provides listeners with a wealth of information to make informed decisions regarding their oral health. Gain deep insights into the evolving world of dental care with a focus on conservation and holistic approaches. #BiomimeticDentistry #HolisticOralCare #InformedDentalChoices

PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin  Tim Wright served as chair of the pediatric dentistry program. He has published over 200 peer reviewed manuscripts, edited two texts and authored 24 text chapters.  Wright's research interests include human genetics and craniofacial development and he has had over 25 years of NIH funding. He has chaired the Council for Scientific Affairs for the American Dental Association and American Academy of Pediatric Dentistry and is the current President of the American Association for Dental Research.

PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Dr. Morr, a dentist in Miami Florida is the owner and founder of TMprosthodontics. He is a specialist in Aesthetic, Implant, and Complex Restorative Dentistry. After Graduating from the University of Florida with a BS degree in microbiology, he continued his education at Tufts University School of Dental Medicine where he graduated Summa Cum Laude with a DMD degree. He went on to study at the University of Washington School of Dentistry where he received his Masters in the Science of Dentistry degree (MSD) and a certificate in Prosthodontics. Dr. Morr has over 24 years of experience in prosthodontics, the diagnosis and treatment of the deterioration of teeth and their supporting structures. He is known for his Comprehensive treatment Approach as he formulates and executes treatment plans that address not only the mouth, but also the face and jaw. Dr. morr has numerous publications in both textbooks and articles in the areas of Aesthetics, Porcelain Laminate Veneers, Dental mplants, and Complex Restorative Dentistry and Rehabilitation. Dr. Morr is a highly regarded speaker and Educator both Nationally and Internationally and he is considered a leader in the field and highly regarded for his contribution to the field of dentistry.

Real talk between Dr. H and Dr. Vincent Buscemi (@vincedds), a biomimetic specialist located in Bloomfield Hills, MI. After graduating University of Michigan Dental (Class 2014), Dr. Buscemi has been through it all! From his childhood dentist calling him "the worst dentist ever" to an ugly business split, life didn't seem like it was getting any easier for Dr. Vincent.  And yet, Dr. Buscemi now has a very successful biomimetic practice, he's also the creator and host of the Dr. Vincent Buscemi Podcast, and his life happens to be a bit more fulfilling. Listen to learn how he changed his destiny.To learn more about Dr. Buscemi:Website Dr. Vincent Buscemi Podcast: Survival Guide for DentistsInstagramTo learn more about the GLO Good Foundation and their efforts, check out:About Video__________________________If you enjoy the podcast, subscribe and rate ⭐️.If you think a friend will enjoy it, please share it with them.Feel free to join our community at @_teethmatter to ask questions or share your story.  --- Support this podcast: https://podcasters.spotify.com/pod/show/teethmatters/support

On this episode of Mind Body Peak Performance, Nick is joined by and Dr. Chris Rhodes, Founder and CEO of Mimio Health. They explore biomimetic supplementation and its ability to replicate fasting benefits.From the science behind lifespan extension to the potential of biomimetic supplements, they delve into metabolic health, fasting, and the future of regenerative states. Stay tuned for insights on longevity, fasting mimetic molecules, and the impact of validated supplements.Meet our guestMimio Health is a nutritechnology company creating first-of-their-kind biomimetic supplements designed from human biology to recreate the body's innate regenerative systems. Now available to the public, their biomimetic formula (Mimio) was discovered by founder Dr. Chris Rhodes while obtaining his Ph.D. in Nutritional Biochemistry at UC Davis. Designed to study and decode the longevity-enhancing effects of fasting, his research found that there are unique molecules produced in the human body that are only elevated during a 36-hour fast. By taking these “fasting metabolites” and giving them back to our cells, his team could mimic the beneficial effects of fasting and nearly double the lifespan of model organisms. All without any need to fast.Thank you to our partners Outliyr Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Holiday Specials: a roundup article of all the best current deals on technology, supplements, systems and more Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-CourseKey takeaways How Mimio can replicate the benefits of 36 hours of fasting without all the inconvenience. Being smart with fasting enhances metabolic functionality and hunger suppression without negative side effects. Biomimetic supplementation can increase health span and lifespan by 96% with the right practices. Fasting can even have great benefits for active individuals like athletes who exert their muscles daily.Links Watch it on YouTube: https://youtu.be/wWnboOqZX_4 Full episode show notes: mindbodypeak.com/134Connect with Nick on social media Instagram Twitter YouTube LinkedInEasy ways to support Subscribe Leave an Apple Podcast review Suggest a guestRelated shows EP 114 - Shredded in 30 Days: the Ultimate Fat Loss ProtocolDo you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you!Be an Outliyr,Nick

DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin   James Otten, DDS Bachelor of Science in Zoology & Minor in Microbiology University of Arkansas 1977 Doctor of Dental Surgery, University of Missouri-Kansas City School of Dentistry 1981 General Practice and Hospital Dentistry Residency-Certificate, Veterans Administration Medical Center in Leavenworth, Kansas 1982 Center for Advanced Dental Studies, St Petersburg FL, Completion of Curriculum in Advanced Restorative Care and the Evaluation, Diagnosis and Treatment of Occlusal and Temporomandibular Disorders 1989-1993 The Pankey Institute, Key Biscayne FL, Completion of Curriculum, Continuum I-VI plus Advanced Studies, 1991- present Piper Education and Research Center, St Petersburg FL, Seminars I-III, Advanced Diagnosis, Management and Treatment of TM Disorders, 1994-2013 Other: Compiled over 3500 hours of Continuing Education in the study of Occlusion, TM Disorders, Facial Pain, Esthetics, Invisalign Certification, Implant and Prosthodontic Restorative care. Associate Professor Prosthodontics University of Missouri-Kansas City School of Dentistry 1982-83 Fellow, American College of Dentists Visiting Faculty, L.D. Pankey Institute -1996-current Visiting Faculty, Newport Coast Orofacial Institute, Newport Beach CA 2010- present L.D. Pankey Institute – Associate/Lead Faculty 1999 – current Provost, L.D. Pankey Institute 2005 -2012 L.D. Pankey Institute Board of Directors/Advisors 2005 – current Medical Staff Lawrence Memorial Hospital Department of Surgery-current Private Practice Lawrence Kansas 1984 – present   Drew McDonald, DDS, MS Dr. McDonald attended dental school at the prestigious Creighton University in Omaha, Nebraska. Known for it's rigorous academic curriculum and intense clinical training, Dr. McDonald received many academic accolades while at Creighton including inductions into Omicron Kappa Upsilon (National Dental Honor Society) and Alpha Sigma Nu (Honor Society of Jesuit Universities). He also served in leadership positions as class president and student body president and on alumni relations committees. After graduating Cum Laude from Creighton, Dr. McDonald was accepted as one of only three residents nationwide into the University of Missouri-Kansas City Orthodontics program, a renowned two-and-a-half year, full-time residency known for its clinical excellence. Dr. McDonald graduated in December of 2016 with his certificate in orthodontics and master's degree in Oral and Craniofacial Sciences. When away from the office, Dr. Drew is a “girl-Dad” to two daughters, a self-proclaimed grill master, and minimally talented yet enthusiastic golfer, you can find him taking in a Lobo game, and spending time outdoors with his family.

DOT - Use the Code DENTALDIGEST for 10% off olsenna.com Olsen Facebook Olsen Instagram Olsen Linkedin Olsen Youtube https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin   Marco Gresnigt graduated summa Cum Laude in 2005 at the university of Groningen, the Netherlands. In January 2012 he obtained his PhD on clinical and laboratory evaluation of laminate veneers. Besides working at the university, he works as a dentist in a center for special care. Marco lectures at the Center for Dentistry and Oral Hygiene, and teaches masters students in a specialized program on esthetics and prosthetic dentistry. Besides writing scientific articles, he has published several articles on minimally invasive and adhesive dentistry in dental journals, and teaches post-graduate courses. He obtained several awards like: the NVGPT publication prize, Boering prize and Cavex prize. Since 2014 Marco became a member of the international Bio-EmulationTM group.

DOT - Use the Code DENTALDIGEST for 10% off olsenna.com Olsen Facebook Olsen Instagram Olsen Linkedin Olsen Youtube https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Dr. Markus B. Blatz is Professor of Restorative Dentistry, Chairman of the Department of Preventive and Restorative Sciences and Assistant Dean for Digital Innovation and Professional Development at the University of Pennsylvania School of Dental Medicine in Philadelphia, Pennsylvania, where he also founded the Penn Dental Medicine CAD/CAM Ceramic Center, an interdisciplinary venture to study emerging technologies and new ceramic materials while providing state-of-the-art esthetic clinical care. Dr. Blatz graduated from Albert-Ludwigs University in Freiburg, Germany, and was awarded additional Doctorate Degrees, a Postgraduate Certificate in Prosthodontics, and a Professorship from the same University. Dr. Blatz is co-founder and past President of the International Academy for Adhesive Dentistry (IAAD) and a founding member of the European Academy of Digital Dentistry (EADD). He is a board-certified Diplomat in the German Society for Prosthodontics and Biomaterials (DGPro) and a member of multiple other professional organizations, including the American Academy of Esthetic Dentistry, the European Academy of Esthetic Dentistry, the International College of Prosthodontists, the American College of Prosthodontists (honorary member), Academy of Osseointegration, and O.K.U. Honor Dental Society. He is the Editor-in-Chief of Compendium of Continuing Education in Dentistry, Associate Editor of the Journal of Esthetic and Restorative Dentistry and of Quintessence International, Section Editor for the International Journal of Prosthodontics, and serves on the editorial boards of numerous other recognized scientific dental journals. He is coauthor of the international bestseller “evolution – contemporary protocols for anterior single-tooth implants”, which has been translated on over 8 languages. Prior to joining Penn Dental Medicine as Chairperson of the Department of Preventive and Restorative Sciences in September 2006, Dr. Blatz was at Louisiana State University (LSU) Health Sciences Center School of Dentistry in New Orleans, where he served as Chairman of the Department of Comprehensive Dentistry and Biomaterials and Assistant Dean for Clinical Research. During his tenure at LSU, Dr. Blatz also directed the Masters of Science in Oral Biology Program and was a senior faculty member in the Department of Prosthodontics. From 1994 to 1998 he was an Assistant Professor and from 1998 to 1999 a senior faculty member in the Department of Prosthodontics at Albert Ludwigs University Freiburg School of Dentistry in Freiburg, Germany. A widely published and internationally respected lecturer, Dr. Blatz's main focus within clinical practice and research is esthetic dentistry with an emphasis on implantology and dental materials, particularly ceramics and adhesion. Dr. Blatz is the recipient of multiple teaching and research awards and has published and lectured extensively on dental esthetics, restorative materials, and implant dentistry. He was recently named one of the “World's Top 100 Doctors in Dentistry”.

DOT - Use the Code DENTALDIGEST for 10% off olsenna.com Olsen Facebook Olsen Instagram Olsen Linkedin Olsen Youtube https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin   Dr. David Hornbrook is a gifted clinician and product researcher turned mentor. Through education, Dr. Hornbrook guides participants of his instructive events to the realization that they, too, possess the ability to practice aesthetic dentistry at the very highest level. He is one of dentistry's most famous faces and one of the pioneers of live-patient, hands-on clinical education, as the founder and past director of Pac-live and the Hornbrook Group. He has been a guest faculty member of the post-graduate programs in Cosmetic Dentistry at Baylor, Tufts, SUNY at Buffalo, UMKC, and the UCLA Center of Cosmetic Dentistry. Dr. Hornbrook lectures internationally on all facets of aesthetic and restorative dentistry and has published articles in all of the leading dental journals. A prolific researcher and materials enthusiast, he consults with numerous manufacturers on product development and refinement. Dr. Hornbrook's warm and engaging style earns him the highest possible marks from participants and meeting sponsors.

olsenna.com Olsen Facebook Olsen Instagram Olsen Linkedin Olsen Youtube https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin   Dr. David Hornbrook is a gifted clinician and product researcher turned mentor. Through education, Dr. Hornbrook guides participants of his instructive events to the realization that they, too, possess the ability to practice aesthetic dentistry at the very highest level. He is one of dentistry's most famous faces and one of the pioneers of live-patient, hands-on clinical education, as the founder and past director of Pac-live and the Hornbrook Group. He has been a guest faculty member of the post-graduate programs in Cosmetic Dentistry at Baylor, Tufts, SUNY at Buffalo, UMKC, and the UCLA Center of Cosmetic Dentistry. Dr. Hornbrook lectures internationally on all facets of aesthetic and restorative dentistry and has published articles in all of the leading dental journals. A prolific researcher and materials enthusiast, he consults with numerous manufacturers on product development and refinement. Dr. Hornbrook's warm and engaging style earns him the highest possible marks from participants and meeting sponsors.

I'm joined by Dr. Chris Rhodes from Mimio, where we embark on a fascinating exploration into the intricacies of fasting. Discover how Mimio Health has ingeniously crafted a supplement that awakens fasting pathways, all without the necessity of adhering to strict dietary constraints.   Our discussion spans a multitude of topics, including the myriad advantages of fasting, how Mimio facilitates the attainment of these fasting benefits, the unique ingredients that comprise Mimio's formula, the sustainability aspect of supplements, and an array of other captivating insights. I talk about:  06:10 - Importance of cellular health and its impact on future disease 12:50 - Mimio and the holistic approach to longevity 19:30 - Longevity research and the role of fasting 22:30 - Challenges and considerations surrounding fasting recommendations 29:40 - Fasting-like molecules extend lifespan in model organisms 37:40 - Nicotinamide and spermidine for holistic health benefits 48:20 - Unique formulation and bioavailability of Mimio 52:35 - Timing and usage of Mimio for maximum benefits 56:05 - Consistency and benefits of lifelong Mimio use 1:07:00 - The need for more research in supplement formulations   Sponsors: Try BiOptimizers products (including magnesium, sleep breakthrough powder and digestive enzymes) and use my discount code BIOHACKINGBRITTANY for 10% off! Try AG1 and get a FREE 1-year supply of Vitamin D AND 5 free AG1 Travel Packs with your first purchase.   Resources: Try my Hormone Balancing Chocolate recipe! It's delicious and your body and hormones will thank you. My Ebb and Flow Cycle Guide solves all your hormone problems. Confused on what to eat and do during each phase of your cycle? Download it now for all the answers on cycle syncing and hormone balancing.  Visit Mimio's website and use my discount code BIOHACKINGBRITTANY   Let's Connect: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, Google Podcasts

Meet Tess Zigo, CFP, CPA olsenna.com Olsen Facebook Olsen Instagram Olsen Linkedin Olsen Youtube https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Dr. Peter Milgrom is Professor of Oral Health Sciences and Pediatric Dentistry in the School of Dentistry and adjunct Professor of Health Services in the School of Public Health at the University of Washington. He directs the Northwest Center to Reduce Oral Health Disparities. He holds academic appointments at Case Western University, University of Rochester, and University of California, San Francisco. He maintains a dental practice limited to the care of fearful patients and served as Director of the UW Dental Fears Research Clinic. Dr. Milgrom's work includes research on xylitol, the effectiveness of fluoride varnish and iodine in preschoolers, clinical efficacy and safety of diammine silver fluoride, motivational strategies to increase perinatal and well child dental visits in rural communities, and studies of cognitive interventions in pediatric and adult dental fear. The NIH, Maternal and Child Health Bureau, HRSA, and the Robert Wood Johnson Foundation support his work. Dr. Milgrom is author of 5 books and over 300 scientific articles. His latest book, Treating Fearful Dental Patients, was published in 2009.   Dr. Milgrom was Distinguished Dental Behavioral Scientist of the International Association for Dental Research for 1999. In 1999, and again in 2000, his work was recognized by the Giddon Award for research in the behavioral sciences in Dentistry. He received the Barrows Milk Award from IADR in 2000, recognizing his work for public health including the development of the Access to Baby and Child Dentistry (ABCD) program in Washington State. In 2003, Dr. Milgrom received a Special Commendation Award from the National Legal Aid and Defenders Association and the University of Washington Medical Center Martin Luther King, Jr. Community Service Award. In 2010, he received the Aubrey Sheiham Research Award for his work on xylitol. He serves on scientific review committees for the NIDCR, NIMHHD, NINDS, Center for Scientific Review at NIH and as a consultant to the FDA. In 2005, Dr. Milgrom was appointed the SAAD Visiting Professor of Pain and Anxiety Control at the King's College Dental Institute, University of London, UK for a six-year term. In 2008 he was awarded the degree of Doctor Honoris Causa from the University of Bergen, Norway in recognition of his work in social and behavioral dentistry. In 2012, he received the University of California, San Francisco Dental Alumni Gold Medal for his contributions to Dentistry. In 2012 he was also awarded the Norton Ross Award for Excellence in Clinical Research by the American Dental Association. In 2013, he was appointed to the Council of Scientific Affairs of the American Dental Association. In 2014, he received the Irwin M. Mandel Distinguished Mentor Award from the IADR. In 2015, he served as HMDP Expert in Dental Public Health for the Singapore Ministry of Health. Dr. Milgrom received his DDS from the University of California, San Francisco in 1972 and had a previous position at the National Academy of Sciences, Engineering, and Medicine. In the last few years, Dr. Milgrom has spoken to dental associations in Argentina, Colombia, Peru, Philippines, and USA and at major universities in USA and abroad.

 DOT - Use the Code DENTALDIGEST for 10% off olsenna.com Olsen Facebook Olsen Instagram Olsen Linkedin Olsen Youtube https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin https://www.kokicheducation.com Dr. Kokich Jr. received his dental degree from Tufts University School of Dental Medicine in 1996 and completed a general practice residency at the University of Washington Medical Center in 1997. He remained at the University of Washington for his orthodontic training where he obtained his Masters in Orthodontics in 1999. Since then he has remained on faculty in the Department of Orthodontics as an Affiliate Assistant Professor while maintaining a private practice in Tacoma, Washington. He has received the Charles L. Pincus Research Award for Clinical Research from the American Academy of Esthetic Dentistry and his current research and publications are primarily involved with esthetic, interdisciplinary dentistry. He is a diplomate of the American Board of Orthodontists and a member of both the Angle Society and the American Academy of Esthetic Dentistry. He has written or co-written four book chapters as well as numerous scientific and review articles. Dr. Kokich Jr. has given over 240 lectures nationally and internationally on interdisciplinary dentistry and dental esthetics emphasizing comprehensive treatment planning and the importance of properly sequencing orthodontic, periodontal, and restorative treatment.

DENTAL ONLINE TRAINING link DOT: Use DENTALDIGEST for 10% off  Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Jim Janakievski D.D.S., M.S.D. Jim Janakievski received his D.D.S. from the University of Toronto, which was followed by a general practice residency. After several years in general practice, he completed his post-graduate training at the University of Washington, where he received a certificate in Periodontology with a M.S.D. degree and a fellowship in Prosthodontics. He began his academic position at the University of Washington as assistant director of Graduate Periodontics and is currently an affiliate assistant professor. Dr. Janakievski is a Diplomate of the American Board of Periodontology, and a Fellow of the American Academy of Esthetic Dentistry. He is a reviewer for several dental journals and has published in the area of interdisciplinary dentistry, dental implants and tooth autotransplantation. Dr. Janakievski teaches at Spear Education in Scottsdale Arizona. In addition, he participates in practice based clinical research through the McGuire Institute. He maintains a private practice in Tacoma, Washington.

Dr. Jeanette MacLean is a Diplomate of the American Board of Pediatric Dentistry, Fellow of the American Academy of Pediatric Dentistry, owner of Affiliated Children's Dental Specialists in Glendale, Arizona, and mother of two. She received her dental degree, with honors, from the University of Southern California in 2003 and completed her specialty training in pediatric dentistry in 2005 at Sunrise Children's Hospital through the University of Nevada School of Medicine. Dr. MacLean has become an internationally recognized advocate and expert on minimally invasive dentistry, appearing in newspapers, magazines, television, and continuing education lectures on this hot topic. Most notably, she was featured in the July 2016 New York Times article “A Cavity Fighting Liquid Helps Kids Avoid Dentists' Drills,” which brought national attention to the option of treating cavities non-invasively with silver diamine fluoride.

Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin https://www.omnismile.com/about Dr. Andrew C. Johnson completed his general dental and prosthodontic training at the University of Tennessee Health Science Center and has been practicing in Northwest Arkansas since 2013.  Along with his specialist certificate, Dr. Johnson earned a master's degree in dental science researching CAD/CAM restorative techniques and emerging digital dental materials. He maintains certifications by both the American Board of Prosthodontics and the National Board for Dental Laboratory Technology, and serves as adjunct faculty with the UTHSC Advanced Prosthodontics Program.  Dr. Johnson has been published in multiple dental journals and lectures internationally on a variety of technological developments in dentistry.   He consults for a wide range of dental clinicians, suppliers, manufacturers, and developers on topics ranging from three-dimensional imaging and virtual treatment planning to computer-guided and robotic surgery as well as digital prosthesis design, production and long-term complication management.  However, his broader professional interests include process scaling, provider calibration, and workflow disruption.