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IP Fridays - your intellectual property podcast about trademarks, patents, designs and much more
Creator Economy Law: What Every Creator Needs to Know About AI, Platforms, and Their Rights – Interview with Franklin Graves of Linkedin – IP Fridays Podcast – Episode 176

IP Fridays - your intellectual property podcast about trademarks, patents, designs and much more

Play Episode Listen Later Jun 26, 2026 36:31


My co-host Ken Suzan and I are welcoming you the episode 176 of the IP Fridays Podcast. Today's interview guest is returning guest Franklin Graves, who is a senior counsel at Linkedin and teaching IP law at Emerson College. With my co-host Ken Suzan he is discussing how the law for creators has dramatically changed in the past years. Franklin Graves is expressing his personal views and not the views of Linkedin or Microsoft. He is talking about the paper “Upload Complete” before he joined Linkedin. Bio: https://www.linkedin.com/in/franklingraves/ Paper: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5271442 Website: https://creatoreconomylaw.com/ But before we jump into this interview, I have news for you! Richard Meade, a judge on the UK High Court and one of the most prominent figures in European patent law, was appointed Lord Justice of Appeal at the British Court of Appeal on June 12, 2026. Meade played a key role in numerous landmark British patent decisions, particularly in the area of standard-essential patents (SEPs) and FRAND licenses. In Insulet Corp. v. EOFlow Co., No. 2025-1807, the U.S. Court of Appeals for the Federal Circuit completely overturned the original $452 million judgment (which had already been reduced by the District Court to $59.4 million) in favor of Insulet. In its decision of June 2, 2026, in the case of Fujifilm v. Kodak, the UPC Board of Appeal provided comprehensive clarifications regarding so-called “long-arm jurisdiction”—that is, the question of whether the UPC can also rule on national patent claims outside the UPC territory (such as in the United Kingdom). In 14 guiding principles, the judges established specific procedural rules for various categories of cases. There is no automatic UPC jurisdiction over national patent claims outside the UPC territory. The Munich Regional Court has issued an arrest warrant against the managing director of Polytech Health & Aesthetics GmbH because he is alleged to have continued to exploit the Brazilian company Silimed's patent for breast implants despite a preliminary injunction. A number of IT and automotive industry associations—which are among the most frequent users of Inter Partes Reviews (IPR) at the U.S. Patent and Trademark Office—have filed an amicus brief with the Supreme Court, urging the Court to grant Google's certiorari petition. An attorney for a Las Vegas performer has asked a California federal judge to temporarily prohibit Taylor Swift from using “The Life of a Showgirl” as a trademark while the trademark lawsuit is pending. Swift's attorney called the lawsuit baseless. And now let's hear Ken discuss creator law with Franklin! AI, Platform Law, and the Creator Economy: What Businesses Need to Know Now Franklin Graves has spent his entire career watching digital content move through systems that most people never see. He started in marketing at a major music label right out of law school, then represented individual creators on YouTube in a pro bono capacity, then moved to the platform side at Eventbrite, and today works as Senior Product Counsel at LinkedIn, where he focuses on AI, data, and the regulatory questions that come with both. His recently published law review article, Upload Complete: An Introduction to Creator Economy Law, is the first academic paper to address the creator economy as a distinct legal field. In a recent episode of the IP Fridays podcast, he spoke with host Kenneth Suzan about responsible AI development, platform regulation, and what it actually means to own your audience in a world where the rules keep changing overnight. From Content Creator to Platform Lawyer The through-line in Graves’ career is a genuine understanding of how content moves from an idea in someone’s head to an audience on a screen. That experience, he argues, is precisely what in-house counsel needs right now. Lawyers working on AI and product development cannot afford to sit at a distance from the technology they are advising on. They need to use the tools, experience them as a creator or end user would, and understand the nuances of how a product actually operates before it reaches the public. Understanding the product first is the precondition for everything else. That philosophy translates directly into how he approaches responsible AI implementation. The landscape of AI standards is crowded: NIST frameworks, the EU AI Act, sector-specific guidance, and a growing body of industry-adopted best practices. The challenge for in-house counsel is not knowing that these standards exist. It is making them actionable for the engineering and product teams they support. Abstract principles need to become concrete controls and workflows. Graves offers one practical shortcut: most companies already have open source software review processes that involve the right stakeholders, the right sign-off levels, and the right security checks. Layering the specifics of generative AI or large language models onto those existing processes is far more efficient than building something new from scratch. A Fragmented Regulatory World The geopolitical dimension of AI regulation is something Graves thinks about constantly in his role at LinkedIn. The EU AI Act, shifting US executive orders, and country-specific approaches to data privacy have created a regulatory environment that can change the rules of the game without warning. His analogy is instructive: creators have long understood what it means to build a community on a platform they do not own. An algorithm change, a policy update, or a government ban can wipe out years of audience-building overnight. Businesses deploying AI tools globally now face a structurally similar problem. The response, for creators and for platforms alike, is to build resilience rather than rely on stability that may not last. TikTok is the clearest recent example. When the platform faced the prospect of being shut down in the United States on national security grounds, it triggered a broader conversation about platform dependence that had been building for years. Creators who had invested their entire business in one platform suddenly confronted the possibility that their audience could simply disappear. The lesson is not that platforms are bad. It is that concentration of any kind, whether it is your audience, your data pipeline, or your regulatory compliance strategy, creates fragility. What Is a Creator, Legally Speaking? One of the central contributions of Graves’ law review article is definitional. The terminology matters more than it might seem. When courts and regulators talk about creators without a shared understanding of what that word means, the resulting legal analysis tends to miss the mark. Graves draws a distinction between users who post content, creators who post with the intent to build an audience and eventually monetize it, and influencers, a subset of creators who are actively running a small business through their content. The difference is intent. A parent posting family photos on Facebook is a user. Someone building a subscription community around their professional expertise is running a business, and the legal framework that applies to them should reflect that. That distinction matters practically when it comes to liability. As more creators build their own platforms, whether through custom membership sites, open source tools like Ghost, or federated social networks, they take on obligations that previously fell to large platforms: content moderation policies, privacy notices, terms of service, and compliance with data regulations across multiple jurisdictions. A creator in Tennessee running a membership platform with subscribers in Germany is operating a global business, whether they think of themselves that way or not. Protecting Children Online: A Question Without a Clean Answer The tension between age verification and privacy is one of the more difficult problems in platform law right now. Australia, several European countries, and a growing number of US states have introduced or passed minimum age requirements for social media accounts. The technical challenge is real: verifying age online requires collecting identifying information, and collecting identifying information creates privacy risk, particularly for the young people the laws are designed to protect. Who should bear the responsibility for that verification is also unresolved. Is it the platform? The app store? The mobile operating system? Graves does not pretend there is a clean answer, but he points to the mobile layer as an underexplored option. The Apple App Store and Google Play Store already have significant leverage over which apps reach users on their devices. Whether that leverage should extend to age verification is a question that deserves more attention than it currently receives. The Right of Publicity in the Age of AI Voice cloning, digital replicas, and AI-generated synthetic media have pushed the right of publicity into territory that traditional IP law was not designed to cover. Trademark law, copyright law, and existing publicity rights each capture part of the problem but none of them covers it completely. The result, as Graves describes it, is a period of experimentation: lawyers filing trademarks on vocal sounds and phrases, states updating their publicity statutes to explicitly mention artificial intelligence, and entertainment unions negotiating over who controls a performance and any AI-generated iterations of it. Tennessee’s Elvis Act is a concrete example of the legislative response: the state updated its right of publicity law to include voice and to reference AI directly. Similar efforts are underway elsewhere. The underlying challenge is calibrating protection so that it gives creators and performers meaningful control over their likeness and voice without foreclosing the development of generative AI systems that depend on broad rights to process and learn from content. Somewhere between those two interests, a workable legal framework needs to emerge. The brand deal context may be where the issue becomes most immediately practical. When a brand partners with an influencer and the campaign involves generative AI in any form, the contract needs to address control explicitly. Who has final approval over how the influencer’s likeness or voice is used in AI-generated deliverables? What happens to those assets after the campaign ends? These are not hypothetical questions. They are contract drafting problems that any brand counsel or creator attorney should be addressing today. What Comes Next Graves is cautious about predictions, but his sense of direction is clear. The regulatory environment will continue to fragment before it converges. The right of publicity will be updated, imperfectly, in more jurisdictions. Creators will continue to move toward owning more of their infrastructure. And the lawyers who do this work best will be the ones who understand the technology well enough to translate it into practical, defensible decisions for the people they advise. Full Transcript: Ken Suzan: Thank you, Rolf. Our returning guest today is Franklin Graves. Franklin is the founder and editor of Creator Economy Law, a website and newsletter that educates creator economy professionals on the intersection of law and policy with the world of creators, brands, and platforms. Franklin also published the first law review article focused on the creator economy, Upload Complete, an introduction to creator economy law. He regularly appears across news and media outlets as a commentator and contributor with a focus on educating creators and raising awareness of all legal aspects of the creator economy. Franklin is based in Nashville, Tennessee. Ken Suzan: Franklin was invited to participate as one of the creators and creator economy professionals in the first ever White House creator economy conference. Franklin works full time as a product counsel at LinkedIn Corporation. As a member of the product and data team, he focuses on emerging issues in AI and data. Franklin previously held roles on the technology law group at HCA Healthcare, the commercial legal team at Eventbrite, and the business and legal affairs team at Naxos Music Group. Welcome back Franklin to the IP Fridays podcast. Franklin Graves: Thank you so much for having me. It is exciting to be back and reflecting over the last decade since I last joined and also the paper that I wrote that dives into this in more detail. So I really appreciate it. And yes, full disclosure, I currently work for LinkedIn, which is a subsidiary of Microsoft. I’m here in my personal capacity to talk about this, the paper I wrote before joining LinkedIn and all of that. So thank you so much for having me back. Ken Suzan: Excellent. So Franklin, since your last appearance on IP Fridays in 2017, your career has evolved significantly. You are now senior product counsel at LinkedIn focusing on AI and data. How has working inside a major tech platform changed your perspective on the legal frameworks governing digital content compared to when you were viewing it purely from the creator side? Franklin Graves: I appreciate that question because when I wrote the article, I did not work for LinkedIn. And I had been coming from a history in my career where I, right out of law school, worked for a record label like we talked about almost 10 years ago. And I was on the content creation side. I’ve represented a major distributor of classical music digitally at the time. And that was my first exposure to understanding how content was taken from the initial inception stage from creators and routed through all the various digital platforms that were at the time still evolving and even arguably still today continue to evolve. The early days of YouTube Music launching and then Apple Music launching, and then going through all the phases of high-res audio and everything that came after that. So that was an interesting perspective to start my career with. And then I went to Eventbrite, which is a ticketing platform, but was also focused on elevating event creators. They kind of took on that moniker of “Hey, we are event creators that we support.” And that was arguably my first exposure to the platform side, the tech platform side of it, because Eventbrite is a platform. And so then I evolved from there in my personal capacity, in a pro bono capacity representing individual creators across the YouTube space. And that’s what we talked about a little bit back when I first came on the podcast. Franklin Graves: Over the last decade, it’s been a chance to grow my own understanding of the creator economy. The terminology “creator economy” came around. And then now on the other side of it, having written the article and all that, and now being fully in-house at LinkedIn, I truly am experiencing a social media platform. LinkedIn is of course arguably way more than just the platform itself. There are so many different avenues to it, but it is a chance for me to understand what it is like working for a company that is operating the platform that people are distributing content on. There’s a user journey to content and all of that. So it’s definitely enhanced and given me a different perspective from a major tech platform side. And part of my role at LinkedIn is really heavily focused on understanding regulation and how that from an AI and data perspective impacts the company. And so I’ve been really leveling up my game over the last year and a half that I’ve been here, understanding mostly EU regulations, but also US regulations that are still in their infancy when it comes to AI. But really when it comes to privacy and data, those are pretty well established across the board. It’s been kind of a combination of what I learned at Eventbrite, because I went to Eventbrite when GDPR was going into effect. And so that was an eyes-wide-open moment of getting in the weeds with negotiating data processing agreements, understanding data transfers and cross-border data transfers and the like. So it’s been kind of an evolution as the laws and regulations have evolved. So has my career, so has my own understanding, so have the platforms’ responses to those laws and regulations. And I’m sure that probably resonates with a lot of your listeners who have also been growing their practice and their understanding as the laws and regulations in this realm have been evolving too. Ken Suzan: Yes, indeed. Now let’s switch gears and talk about AI. You advise on AI and data daily. As platforms integrate generative AI tools into their tech stacks, what are the most critical best practices in-house counsel should be adopting right now to embed responsible AI principles into product development? Franklin Graves: So as an attorney, one of my key roles is to understand the technology. Even representing creators and working for creator platforms, that’s something I’m constantly trying to do: put myself in the shoes of being a creator. And I think I talked about this last time I was on, but I come from a background where I was working for a major label doing marketing, video editing, social media work. And I was creating content. I understood the whole life cycle from the inception point of an idea to execution and then to the final delivery and distribution of that content to an audience within a major music label. And so part of that is the same thing that I think attorneys, especially in-house, should be doing: using the tools that the product and engineering teams are either developing in-house or partnering with third parties to develop, or a combination of the two. Using them, understanding them, using them as a creator would, using them as an end user or a client or customer would. And making sure that if you understand the product and understand the nuances of how it operates, and being a part of the iterations of that internally before it fully ramps, that really gives you a chance to understand: okay, we have a lot of responsible AI principles and standards and protocols that are in existence right now, whether it’s NIST, whether it’s based on the EU AI Act or anything and everything in between. It’s understanding how to apply those and bring those into a product and an engineering environment in a way that is practical and actionable for the people that you’re supporting, the stakeholders you’re supporting. So I think one of the critical best practices is, number one, understand the product or features that you’re supporting. Franklin Graves: And then understand how you as an attorney can use your expertise and understanding of responsible AI practices, whether it’s a regulatory standard or an industry-adopted standard or a hybrid of the two, to leverage those and implement those, break those down and make them into actionable controls and processes and flows that work within your existing infrastructure. That’s a lot of high-level talk, but that’s the general idea. One concrete example we talk about frequently is with open source AI. If you’re working with a product team or an engineering team that is taking an off-the-shelf open source model and bringing that in-house, a lot of times companies have pre-existing open source processes that cover the use of open source software or code. Piggyback on that. That’s the easiest quick win for attorneys: leveraging your existing open source processes to just build on top of that the AI flavor and layering. It’s not very much that you have to do, but the underlying process of the key stakeholders that need to be involved in the review, whether it’s security, whether it’s executive sign-off if it gets to that point, even export control considerations should already be part of your existing open source software process. So layering in on those existing processes the specifics of generative AI or large language models that you’re trying to bring in is a great way to put this into practice. Ken Suzan: Now looking at the geopolitical landscape that we currently have, we have the EU AI Act setting strict standards and shifting US executive orders. How should platforms and brands prepare for this fragmented regulatory environment when deploying AI tools to a global user base? Franklin Graves: It’s a great question. It’s something that is still evolving, I think is fair to say. I would equate it, as I do in the paper that I wrote, to how creators and arguably brands don’t own the platforms that they’re building their communities on. That spawned this concept of de-platforming or going into building your own platform, a decentralized platform of sorts, and owning your community. That gives you that control and takes away the level of instability that can come for creators trying to build a business on a platform they don’t own, they don’t control when certain updates happen, when algorithms change, when tools and functionalities either become available or go away completely. So it’s very similar to what we’ve been experiencing in a regulatory environment where we have geopolitical complexities, for lack of a better term, that can overnight seemingly disrupt the way in which a platform or even a multinational brand is able to connect and reach an audience or continue to leverage the user base that they’ve built. I think TikTok is a great example of that, where it became a national security concern and suddenly it was facing an executive order that required it to be effectively disabled in the US or completely owned and operated by a US entity. All the mechanics and technicalities of whether it’s actually possible and still have a global platform with a global user base is a whole different discussion. But that’s an example of very similar considerations that are now not just a discussion point at the creator level or the individual brand level, but also in a much broader context at a platform level as well. Ken Suzan: Franklin, let’s now shift gears and talk about your article. In your recently published journal article, Upload Complete, which we will have linked in our show notes, you advocate for a shift in terminology from internet creator law, a term used during our first podcast almost a decade ago, to creator economy law. Why is this distinction important and how does it change the way legal practitioners should view the ecosystem of creators, brands, and platforms? Franklin Graves: Oh yes, this is part of the reason why I wanted to write the article: to lay this foundation of understanding. Because at the time I’d written the article, the term creator economy and creator had really not appeared but for maybe once in an actual court decision. And it was kind of focused on influencers and this concept, and it was just not getting it right. And so it was also, as you mentioned, when we first spoke I was even using the term internet creators. And I think that was something that was common at the time. The “internet” portion as a qualifier has since dropped off. And now for purposes of the creator economy, the term creators refers to individuals, it can be small businesses, which is what we’ve seen from a regulatory standpoint, how these small businesses are being impacted by regulations. But essentially creators in the article I pin in the context of intent. What is the intent behind the person or the small business that is posting content, trying to build a community and form a community in a virtual environment? And then that can even spill over into real physical world environments. And so the intent is kind of what I look at. Franklin Graves: And I have a chart in the article that has a diagram showcasing the overlap of what I refer to as “users generating content.” It’s a play on the concept of user-generated content, UGC. Users generating content is that large bucket of anyone posting on a platform of some kind. And within that large bucket, that large circle, are smaller subsets. You have creators, you have brands. Those are really the two buckets you can put people into. Otherwise it’s like your grandmother or your parents posting content on Facebook or Instagram, and those are everyday users of a platform. The distinction to get into that subcategory of being a creator more so has been analyzing the intent behind the posting. Are you posting content to build an audience, to build a community, to eventually have a chance to monetize the following that you’re bringing in or sell services or something like that? Brands are posting for that reason. Creators are maybe posting for that same reason. But even within the creator category, there’s a subcategory of influencers that are trying to sell something, that are trying to build more than just an awareness of who they are, their influence. They are trying to do brand deals, partnership deals, upsells and all that, and start an actual small business aside from just the content itself that they’re creating. So that’s kind of the distinctions that I make in the paper. And that’s why it’s important to understand and lay that foundation, that anyone can post content online, but the intent, the why behind their posting that content, really does ultimately matter, especially when you’re looking at it from a court case or from a regulatory standpoint. Ken Suzan: Now, Franklin, we’re seeing unprecedented geopolitical activity around platform ownership. For example, the US legislation targeting TikTok and Brazil’s recent temporary ban of X. How do these macro-level battles impact the day-to-day livelihood of creators? And how can they legally and operationally protect themselves? Franklin Graves: So the shift that we’re seeing, and I alluded to this earlier in our conversation, is this concept of Web 3. And that term may or may not be really popular anymore, but that’s essentially what we’re looking at: a shift into a federated, decentralized operation of a platform. So instead of one owner, one company, one entity owning and operating the platform, it’s decentralized. Anyone can start up a server, and it’s interoperable, meaning anyone can plug and play and connect to that larger network. And it creates this unified social network experience. Within each operating node of that network, there can be your own decisions around content moderation, your own decisions around the hosting providers you use, where you’re operating out of, the terms and conditions that apply to that. But the flip side is that instead of creators posting and sharing in a closed environment run and controlled by a singular entity, you’re now experiencing a peer-to-peer type operation where your experience can change based on which server, which node, which user you’re engaging with. You might have content that’s acceptable in one area but not acceptable in another, and maybe it just doesn’t even show up in that other area. Franklin Graves: But from a liability standpoint, as creators start to build their own networks and communities, even outside of a concept like the fediverse, it’s even down to creators building their own communities through online courses, subscription membership-based platforms that they run on their own website. There’s open source software out there, even something called Ghost, where you have memberships. And that is a creator or a small business in the creator economy that is now taking on the obligations that would typically fall upon a platform. They need to take into consideration terms and conditions, privacy policies, legal aspects, and regulatory considerations for running a platform, especially in a global world. So it’s a lot of liability that then shifts over to those small businesses and even brands sometimes that are doing the same thing. Whether it is something as simple or complex as content moderation or all the way up to monetizing an audience, this new world where creators can spin up and run a platform all dovetails back to the concept of creators not feeling like they have control in reaching the audience and the community that they’re building on an individual platform. And so this really became more mainstream conversation with TikTok and the issues around it potentially being shut down in the US. That was kind of the mindset shift and eyes opening for many creators, especially within the influencer subset, of realizing: we need to make sure that we have a way to reach the audience we’ve built if the individual platform that we’ve committed to over the last year or three years or so is no longer available. We need a way to continue that relationship outside of that one platform controlling it. Ken Suzan: Franklin, we have a few minutes left and a number of topics. So I’m going to switch gears and talk about a few issues. First, a major emerging topic in your paper is the evolution of protecting kids online. With state-level age-gating laws like the CAADCA and the recent FTC updates to COPPA, how should platforms navigate the significant tension between strict age verification mandates and the privacy and First Amendment rights of their users? Franklin Graves: Man, that is a whole discussion to unravel. It is a consideration that we’re seeing happen again, going back to the geopolitical nature of everything. Countries like Australia and certain countries in Europe and now even individual states in the US are trying to look at ways, and some of them have already put into place minimum age requirements before you can even sign up for an account with a social media platform. One of the things I’d just highlight quickly here is that one of the tensions is around how you verify someone’s age online and still maintain the ability to be at least pseudonymous. How do you still have a level of privacy, autonomy, and protection when it comes to having to provide something like a driver’s license or have parental consent tied and connected to an account managed by a parent in a situation where maybe it’s not appropriate or not beneficial to the child in that manner? But then maybe there are counterbalancing factors that outweigh that. All of that comes down to the technicalities of how it’s actually implemented and maintaining the sense of openness and freedom that we’ve had on the internet to date. And then the other element there is, since a lot of the internet that we think of today is more so through mobile applications, is it something that the mobile operating system providers and app store providers should be thinking about? So whether that’s the Google Play Store or the Apple App Store, where does that initial age verification need to fall? Is it at the platform level? Is it the app store or mobile device management level or something else? Yeah, there’s a lot to discuss there. And a lot of the issues we’re seeing with how the internet is changing in terms of being able to browse a website without disclosing personal information that might not have been required before is largely stemming from a focus on protecting children online. Ken Suzan: It sounds like, Franklin, we could have another episode covering lots of issues connected with that one topic alone. Franklin Graves: I would absolutely agree with that. There’s a lot going on there. And again, it’s different across the world. And so I know you all have a global listener base. And so there’s a lot of nuances to that whole discussion too, that are worth exploring. Ken Suzan: Last question for today’s episode is regarding the right of publicity. With the explosion of AI-generated synthetic media, digital replicas, and voice cloning, the right of publicity is taking center stage. What are the biggest legal risks for brands partnering with influencers right now? And how can creators protect their most valuable asset, their likeness? Franklin Graves: That’s a great question. I think we’re seeing kind of a throwing-spaghetti-against-the-wall-to-see-what-sticks approach right now by a lot of different parties, whether it’s trademark attorneys, whether it’s general entertainment attorneys or whoever. For example, we’ve seen Taylor Swift filing trademarks to protect certain sounds of her voice and phrasing that she uses. It’s a difficult area because in the realm of generative AI with deep fakes and virtual avatars, that is where it gets tricky, because traditional IP laws are just not able to fully cover that spectrum. It’s a piecemeal approach, but even then it doesn’t fully cover it. So for example, I’m based in Tennessee and a couple of years ago we had the Elvis Act that updated our right of publicity law to add voice and to explicitly reference artificial intelligence. And so that’s the kind of effort we’re probably going to continue to see: efforts to develop some framework around protecting what is essentially a privacy right, in a manner that doesn’t restrict generative AI systems from continuing to develop and operate the way they’re operating now, while layering in those protections so that in the US at least a First Amendment right doesn’t necessarily get squashed, and those traditional well-recognized efforts to not overregulate a technology in its early stages are respected. Franklin Graves: And so I think a lot of what we’re seeing is just a need to update laws. The SAG-AFTRA debate and the strikes that happened around maintaining control of your performance and any iterations of that, or building upon that by a media company that might come later, it’s all on the table right now and still being discussed, still being worked out. I think in the short run, a lot of times if it’s in a brand deal, the key question is: if you are using generative AI to enhance in some way the final deliverable for the campaign, who has control over that? Who has final say and sign-off on how that likeness or that digital replica or that person’s voice is represented? And even outside of the brand space, we’ve seen actors like James Earl Jones signing over certain aspects like their voice and allowing it to continue to be used in these manners powered by generative AI as Darth Vader. And I think I saw something that Boy George was even starting up an AI company that allows musicians, the original recording artist, to rerecord new versions of their masters so that they don’t miss out on that revenue. It’s powered by generative AI, by taking their voice now, which is significantly different than it was back in the 80s, and using generative AI to make it sound closer to the original, but all based on their current performance. So I think it’s still an evolving area. And what’s interesting too is on the platform side, we’re seeing the early stages of platforms like Google starting to acknowledge and rely on the license grant contained in their terms of service for YouTube, which grants them broad rights to use the content to run their platform. So all that to be said, it’s still early stages. I’m very interested to see where we go from here in the future, especially from a global perspective as well. Ken Suzan: Franklin, I could spend hours talking to you about this. You’re such a knowledgeable person on these topics. Maybe in a few years, will we connect again and talk further on AI and all the things that are yet to be developed? Franklin Graves: Thank you. Yeah, it doesn’t have to be another decade. Maybe we can cut it to half a decade, given the pace at which technology is going now. Ken Suzan: Sounds good, Franklin. Thanks again for being on the IP Fridays podcast.

Start with Small Steps
287 - Stuck and Can't Start? SPARK: A Motivation Framework for Brains That Won't Cooperate

Start with Small Steps

Play Episode Listen Later Jun 23, 2026 19:28


I used to think something was wrong with me. I'd sit there knowing a task mattered — knowing it mattered yesterday, last week, last month — and still couldn't get myself to move on it. For years I asked myself the wrong question: why isn't this getting done? The better question, it turns out, is what does my brain actually need to get started? That question changed everything, and it's where SPARK came from.Story. I'm a story person. I don't care that a bird exists — I care about the three hours I spent finding it. When I'm stuck on a task, I ask what's interesting about it, not what needs to get done. Curiosity creates momentum that obligation never will.Purpose. Abstract tasks mean nothing until there's a real person on the other side of them. Whether it's an IT ticket or a podcast episode that isn't coming together, I think about who actually needs this and why — and the task shifts even though the work doesn't.Adventure. Not everything can be an adventure (folding laundry is still folding laundry), but a lot of tasks can become small experiments instead of obligations. Possibility is motivating in a way duty never is.Reality. This one needs care, because it's easy to slide from reality into fear. Fear says you'll end up broken and miss out on life. Reality says every choice is a small vote for the future you're building. I'd rather feed the tiger that's still hiking at 80 than the one that isn't.Kickstart. Some days none of the above works. On those days, the only question that matters is: what's the smallest next possible step? Mow the front yard, not the whole lawn. Put on your shoes, not your whole workout. Starting is the hard part — once you start, momentum tends to take over.You don't need all five letters every time. Pick whichever one fits the moment, and let it do its job. Most of us aren't waking up already disciplined and on fire — and that's not a flaw, that's just being human.If you've been stuck on something, I'd love to know which letter of SPARK actually got you moving. Email me at jill@startwithsmallsteps.com or leave a comment — and until next time, keep taking those small steps.Jill's Linkshttp://jillfromthenorthwoods.comhttps://www.youtube.com/@startwithsmallstepshttps://www.buymeacoffee.com/startwithsmallstepshttps://twitter.com/schmernEmail the podcast at jill@startwithsmallsteps.comBy choosing to watch this video or listen to this podcast, you acknowledge that you are doing so of your own free will. The content shared here reflects personal experiences and opinions and is intended for informational and inspirational purposes only. I am not a licensed therapist, life coach, or mental health professional. Any habits, strategies, or suggestions offered should not be considered a substitute for professional medical, psychological, or counseling advice. Results vary — small steps look different for everyone. You are solely responsible for any decisions or actions you take based on this content.

Montreal Now with Aaron Rand & Natasha Hall
Mennie: In a bombshell admission, Montreal's mayor makes it clear that systemic racism is not an abstract

Montreal Now with Aaron Rand & Natasha Hall

Play Episode Listen Later Jun 19, 2026 9:49


Bite Size Sales
Winning Cybersecurity Sales Strategies: Insights from a Former Buyer Turned Seller on CISO Engagement - Chris Camacho, Co-founder & COO at Abstract

Bite Size Sales

Play Episode Listen Later Jun 17, 2026 39:50 Transcription Available


Are you struggling to capture the attention of Chief Information Security Officers (CISOs) in a saturated cybersecurity market? Join us in this enlightening episode of The Cyber Go-To-Market Talk podcast for cybersecurity sales and marketing teams, where we unpack the secrets to effective cyber security sales strategies that can elevate your approach and drive revenue growth. Host Andrew Monaghan sits down with Chris Camacho, co-founder and COO of Abstract Security, who brings a wealth of experience from his previous roles as a buyer at financial services companies. Chris shares invaluable insights into the shifting dynamics of selling cybersecurity solutions, particularly to Fortune 500 companies. He emphasizes the critical need for cyber sales teams to either reduce current spending or replace existing vendors to gain traction, making a strong first impression that resonates with decision-makers. This episode dives deep into Chris's unique journey from being a buyer of cybersecurity products to becoming a builder and seller, offering listeners a rare perspective on what works and what doesn't in the realm of cyber security sales. With around 3,900 vendors vying for attention in the cybersecurity space, standing out is no easy feat. Chris discusses the challenges of differentiation and the evolving role of AI in both sales and product development, providing actionable insights that can help your team navigate these complexities. Building and maintaining relationships is key in the cybersecurity landscape, and Chris stresses the importance of leveraging networks effectively to understand clients' specific needs. By creating tailored solutions that demonstrate clear ROI, sales teams can not only meet but exceed client expectations. Listeners will walk away with practical takeaways on sales onboarding, sales coaching, and metrics that matter in insurance, all aimed at accelerating growth in a rapidly changing environment. This episode is packed with cybersecurity marketing insights and go to market strategies for anyone involved in cyber security sales. Whether you're part of a startup or an established company, the lessons shared here will empower you to grow sales and enhance team management capabilities. Tune in to The Cyber Go-To-Market Talk podcast for cybersecurity sales and marketing teams and discover how to navigate team challenges while building trust and scaling sales teams effectively. Don't miss out on this opportunity to get better at marketing and drive predictable revenue growth! About the guest: Chris Camacho spent around ten years on the buy side in financial services, an early adopter of vendors like Crowdstrike and Flashpoint, before crossing over to build and sell security products. He is co-founder and COO of Abstract.Chapters:00:51 — Crossing from the buy side to the "dark side"02:55 — Why he bought CrowdStrike and Flashpoint early11:45 — A market with thousands of vendors, and the spend arms race15:33 — Three ways to fill a regional CISO event18:23 — Relationships, Ninja Jobs, and meeting his co-founder22:20 — What he interviews for (and what he doesn't)26:22 — When an AI lab lands in your category29:59 — What CISOs are telling him about AI32:22 — Reduce or replace: the way in now34:17 — AI for sellers, and his 17-year-old BDR Support the showThe Cyber Go-To-Market Talk is the show for cybersecurity sales leaders, founders, CROs, and go-to-market operators looking to improve cyber sales performance and build more predictable revenue growth. Hosted by Andrew Monaghan, founder of Unstoppable.do, covering cyber sales leadership, revenue leadership, sales onboarding, forecasting, pipeline generation, and cybersecurity go-to-market execution.Follow me on LinkedIn for regular posts about growing your cybersecurity startupWant to grow your revenue faster? Check out my cybersecurity sales consulting and trainingNeed ideas about how to grow your pipeline? Sign up for my newsletter.

Mere Mortals Book Reviews
Philosophy Mixed With Business | Zero To One (Peter Thiel) BOOK REVIEW

Mere Mortals Book Reviews

Play Episode Listen Later Jun 17, 2026 16:04 Transcription Available


Abstract ideas made definite.In this episode of Mere Mortals book reviews, I dive into Peter Thiel's 'Zero To One' and why its big-picture thinking resonates more than tactical business how‑to. I explore Thiel's blend of abstract philosophy and concrete startup stories (from PayPal to Palantir) and discuss his contrarian takes on competition, monopoly and the value of being the last mover. I unpack the optimistic vs pessimistic, determinate vs indeterminate lens Thiel uses to read cultures and markets and why these frames can guide founders to build something truly unique rather than drift into “zombie company” territory. I share what made the book engaging for me, where it might fall short if you're after nuts-and-bolts execution and who I think will get the most out of it. Ultimately, it's a concise, idea-rich read that can reorient how you think about differentiation, market definition and creating from zero to one.If you got value from the podcast please provide support back in any way you best see fit!Timeline:(00:00:00) Intro(00:00:35) Introducing Zero to One by Peter Thiel(00:04:27) Contrasting with other business classics(00:07:41) Why high‑level ideas can beat operational minutiae(00:11:03) Who is Peter Thiel? Background and ventures(00:12:52) Verdict: a solid read for entrepreneurs(00:14:00) Value for Value: how to support the show(00:15:08) What's next: upcoming book reviews Connect with Mere Mortals:Website: https://www.meremortalspodcasts.com/Discord: https://discord.gg/Xs9DjsurFqTwitter/X: https://twitter.com/meremortalspodsInstagram: https://www.instagram.com/meremortalspodcasts/TikTok: https://www.tiktok.com/@meremortalspodcastsValue 4 Value Support:Website: https://www.meremortalspodcasts.com/supportPaypal: https://www.paypal.com/paypalme/meremortalspodcast

Oncotarget
Protein Linked to Melanoma Growth May Suppress the Body's Natural Anti-Tumor Immune Response

Oncotarget

Play Episode Listen Later Jun 17, 2026 4:33


BUFFALO, NY – June 17, 2026 – A new #research paper was #published in Volume 17 of Oncotarget on June 8, 2026, titled “DHHC3 interferes with antitumor immunity in melanoma cells.” The study was led by first author and corresponding author Chandan Sharma and corresponding author Martin E. Hemler from the Department of Cancer Immunology and Virology at the Dana-Farber Cancer Institute. Melanoma is one of the most aggressive forms of skin cancer and is highly influenced by interactions between tumor cells and the immune system. Although modern immunotherapies have transformed treatment for many patients, researchers continue to search for molecular mechanisms that enable tumors to evade immune attack and continue growing. In this study, researchers investigated DHHC3, a protein acyltransferase that regulates protein palmitoylation and helps maintain cellular redox balance. Previous studies had linked elevated DHHC3 expression to poor outcomes in several cancers, but its role in melanoma and anti-tumor immunity remained unclear. To explore this question, the team used CRISPR gene editing to eliminate DHHC3 expression in B16F10 melanoma cells. Loss of DHHC3 caused a marked increase in oxidative stress and cellular senescence, as demonstrated by elevated TXNIP expression, increased reactive oxygen species levels, and enhanced expression of senescence-associated markers. Full press release - https://www.oncotarget.net/2026/06/17/protein-linked-to-melanoma-growth-may-suppress-the-bodys-natural-anti-tumor-immune-response/ DOI - https://doi.org/10.18632/oncotarget.28880 Correspondence to - Martin E. Hemler - martin_hemler@dfci.harvard.edu, and Chandan Sharma - csharma@mgh.harvard.edu Abstract video - https://www.youtube.com/watch?v=QQhP2VhzKSE Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28880 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, oxidative stress, DHHC3, anti-cancer immunity, palmitoylation, melanoma To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Liberty Church in O'Fallon, Missouri
Session 3 – Theology Proper (Cont.) (Abstract of Systematic Theology by James P. Boyce)

Liberty Church in O'Fallon, Missouri

Play Episode Listen Later Jun 17, 2026 90:36


Video: https://youtu.be/rXBfeOrwE3c Abstract of Systematic Theology by James Petigru Boyce Session 3 – chapters 6-16 Subject: Theology Proper (The Trinity) Wednesday Logos – 6-17-26 Liberty Church

Landscape Photography World
Ep 255 - Abstract Iceland Landscapes & Arctic Tours with Kévin Pagès

Landscape Photography World

Play Episode Listen Later Jun 16, 2026 66:03


Kévin Pagès took a winding road to Iceland. Born in Spain, raised in France, a year in New Zealand sparked his passion for photography, and studies in Montreal turned it into a career. He's been based in Iceland for eight years now and shows no signs of leaving. His early studio work and cinematic portrait style have evolved into abstract landscape photography, often using drones to explore the shapes and patterns of glacier rivers from above. It's distinctive work that earned him Sony Emerging Photographer of the Year in 2016/2017 and a Broncolor GenNext ambassadorship. In this episode Kevin talks about co-founding Arctic Journeys, a private Jeep based photo tour company, his go with the flow approach to shooting in unpredictable weather, and the realities of pricing, licensing and admin that come with running a photography business. He also shares his thoughts on AI and the growing pressures of social media. I hope you enjoy the show! You can find Kevin's work here: Website: https://www.northpolestudio.com/ Instagram: https://www.instagram.com/north_pole_studio/ Facebook: https://www.facebook.com/northpolestudioiceland/   Listen to this and other episodes wherever you find your podcasts or on https://grantswinbournephotography.com/lpw-podcast Or subscribe to my YouTube channel https://youtube.com/@grantswinbournephotography   Theme music: Liturgy Of The Street by Shane Ivers - https://www.silvermansound.com #icelandphotography #abstractlandscape #dronephotography #arcticphotography #landscapephotography #glacierphotography #photographyworkshops #photographypodcast

And Now For Something Completely Machinima
S6 E230 Exploring “Dysfunction” – A Haunting Second Life Machinima Breakdown (June 2026)

And Now For Something Completely Machinima

Play Episode Listen Later Jun 11, 2026 37:40


What happens when machinima stops telling a story… and instead pulls you inside a fractured mind?In this episode of And Now For Something Completely Machinima, hosts Phil Rice, Tracy Harwood, and Damien Valentine dive deep into “Dysfunction” by Iono Allen—a powerful, unsettling machinima film created in Second Life.This isn't your typical machinima. There's no clear beginning, middle, or end—just a visceral, abstract experience of psychological breakdown, sensory overload, and emotional fragmentation.Is it about mental health? Substance abuse? Political disillusionment? Or something even darker?

Liberty Church in O'Fallon, Missouri
Session 2 – Theology Proper (Abstract of Systematic Theology by James P. Boyce)

Liberty Church in O'Fallon, Missouri

Play Episode Listen Later Jun 10, 2026 87:43


Video: https://youtu.be/rXBfeOrwE3c Abstract of Systematic Theology by James Petigru Boyce Session 2 – chapters 2, 4, 5 Subject: Theology Proper (classical arguments for God, attributes of God) Wednesday Logos – 6-10-26 Liberty Church

Speaking Of Reliability: Friends Discussing Reliability Engineering Topics | Warranty | Plant Maintenance

What is Reliability? Abstract What is the definition of reliability? Outside of the field of reliability, who defines it or what a failure is? Join Mojan and Fred as they explore how reliability is perceived across the product development ecosystem—from customers to suppliers to design engineers—and why the classic “but it met the spec!” defense […]

Oncology Peer Review On-The-Go
S1 Ep218: Unraveling Key Hematologic Oncology Developments at ASCO 2026

Oncology Peer Review On-The-Go

Play Episode Listen Later Jun 8, 2026 24:16


In a live X Spaces discussion hosted by CancerNetwork® in collaboration with the American Society for Transplantation and Cellular Therapy (ASTCT), Marc J. Braunstein, MD, PhD, and Sofia Zahid, MD, highlighted noteworthy presentations and abstracts in hematologic oncology at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting. Together, they discussed the data that may shake up clinical practice across different multiple myeloma, leukemia, and lymphoma populations.Braunstein is an associate professor in the Department of Medicine and course co-director of the Hematology/Oncology System at NYU Grossman Long Island School of Medicine, as well as the fellowship program director of Hematology/Oncology at NYU Langone Health. Zahid is a first-year fellow at NYU Grossman Long Island School of Medicine.The discussion focused on the following abstracts:·      Abstract 7512o   Combining belantamab mafodotin-blmf (Blenrep) with daratumumab (Darzalex), lenalidomide (Revlimid), and dexamethasone produced rapid activity among patients with transplant-ineligible newly diagnosed multiple myeloma in the phase 1/2 BelaDRd study (EUCT-2024-515634-32).o   The progression-free survival (PFS) benefits observed in the trial support further evaluation of the quadruplet in a phase 3 study compared with other novel combination regimens in NDMM.·      Abstract 6505o   Revumenib (Revuforj) maintenance therapy after allogeneic stem cell transplantation showed feasibility in a heavily pretreated cohort of patients with acute myeloid leukemia (AML).o   Outcomes appeared favorable vs historical cohorts, supporting prospective assessment of maintenance menin inhibition among those with AML.·      Abstract 1503o   In a retrospective analysis of electronic medical records for 293 patients who received CAR T-cell therapy for lymphoma (n = 175), multiple myeloma (n = 106), or B-cell acute lymphoblastic leukemia (n = 12), outpatient monitoring was associated with significantly fewer hospital days without increased emergency department visits or 30-day mortality.o   These findings show the potential for lower healthcare utilization for patients who receive CAR T-cell therapy in the outpatient setting.·      Abstract LBA7000o   Adding tafasitamab (Monjuvi) and lenalidomide to rituximab (Rituxan), cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) significantly improved PFS vs R-CHOP alone among those with newly diagnosed diffuse large B-cell lymphoma (DLBCL) in the phase 3 frontMIND trial (NCT04824092).o   The data may support tafasitamab plus lenalidomide and R-CHOP as a potential new standard of care in the frontline treatment of patients with cell-of-origin subtypes of high-risk DLBCL.References Terpos E, Ntanasis-Stathopoulos I, Gavriatopoulou M, et al. Belantamab mafodotin with daratumumab, lenalidomide, and dexamethasone in transplant-ineligible, newly diagnosed multiple myeloma patients: phase 1/2 BelaDRd study. J Clin Oncol. 2026;44(suppl 16):7512. doi:10.1200/JCO.2026.44.16_suppl.7512 Goulart H, Okeleji O, DiNardo CD, et al. Revumenib as maintenance for AML following allogeneic stem cell transplantation. J Clin Oncol. 2026;44(suppl 16):6505. doi:10.1200/JCO.2026.44.16_suppl.6505 Bowen SG, Abdallah N, Pritchett JC, et al. Impact of outpatient CAR T-cell therapy administration on healthcare utilization in patients with hematologic malignancies. J Clin Oncol. 2026;44(suppl 16):1503. doi:10.1200/JCO.2026.44.16_suppl.1503 Lenz, G, Trněný M, Burke JM, et al. frontMIND: phase 3 study of tafasitamab (Tafa) plus lenalidomide (Len) and R-CHOP for patients (pts) with newly diagnosed diffuse large B-cell lymphoma (DLBCL). J Clin Oncol. 2026;44(suppl 17):LBA7000. doi:10.1200/JCO.2026.44.17_suppl.LBA7000

Diseño y Diáspora
725. On Ideal Subjects. How To Be Abstract (URSS/United Kingdom). A talk with Olga Goriunova

Diseño y Diáspora

Play Episode Listen Later Jun 7, 2026 55:23


Olga Goriunova ⁠is a cultural theorist who works at the intersection of technology, media, philosophy, and aesthetics. Born in the Soviet Union, she is now based in the UK. Her research is transdisciplinary and engages questions of subjectivation, art and computing across different scales and modes of operation.In this interview, we talk about her latest book, I⁠deal Subjects: Abstract People of AI.⁠ In it, she explores how data and artificial intelligence abstract people into new genres of “subjects,” mapping the horizon of individual and societal possibility.The idea of “ideal subjects” can be useful for designers and user researchers, especially when trying to understand—and question—the way our online data is produced, relates back to us and models our future.She is helping us to question:  - What kind of "subject" is created through data? - How does data based representation attempt to match a human being? - How come that these data-based abstractions are able to engage our desire and thus direct our becoming in relation to their modelled prescriptions? This episode is part of several lists: Investigación en diseño, Reino Unido y diseño, Rusia y diseño, D&D in English, Filosofía y diseño, Arte y diseño social, and AI en UX. While many of the list titles are in Spanish, the content itself is trilingual. Some episodes are in English, others in Spanish or Portuguese. The list D&D in English brings together all the English-language episodes, and it now includes nearly 50 interviews.

Audio podcast of the Interpreter Foundation
A Scientific Evaluation of the Zelph Revelation

Audio podcast of the Interpreter Foundation

Play Episode Listen Later Jun 5, 2026 19:39


Abstract: Members of the 1834 Zion's Camp expedition inspected a large mound along the Illinois River where a skeleton was uncovered and Joseph Smith had a revelatory experience identifying the individual as Zelph. Recent archeological excavations place the revelation in a chronological and ancient cultural context that now allows additional verification and interpretation of this revelatory event. In addition, with this new information, it is possible to determine whether the individual and location can be interpreted as being a part of the Book of Mormon culture and geography. The post A Scientific Evaluation of the Zelph Revelation first appeared on The Interpreter Foundation.

Oncotarget
Cancer Care Often Overlooked in Humanitarian Crises

Oncotarget

Play Episode Listen Later Jun 3, 2026 4:24


Cancer is increasingly recognized as a major global health challenge, yet for people living through war, displacement, and humanitarian crises, access to even basic oncology services can be difficult or impossible. While emergency responses typically focus on trauma care, infectious diseases, and immediate survival needs, cancer care remains largely absent from many humanitarian health programs. A review paper on this topic was published in Volume 17 of Oncotarget titled “Cancer without borders: Policy frameworks for oncology care in humanitarian and conflict settings.” The study was led by first and corresponding author Pragnesh Parmar, with Gunvanti Rathod as co-author, both from AIIMS Bibinagar, Telangana, India. Full blog - https://www.oncotarget.org/2026/06/03/cancer-care-often-overlooked-in-humanitarian-crises/ Paper DOI - https://doi.org/10.18632/oncotarget.28856 Correspondence to - Pragnesh Parmar - drprag@gmail.com; (ORCID: orcid.org/0000-0002-8402-8435) Abstract video - https://www.youtube.com/watch?v=zXlhIBZyJ6Q Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28856 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, cancer care, humanitarian crisis, tele-oncology, global health policy, oncology triage To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us on social media: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Aging-US
Senescent Muscle Cells Send Molecular Messages That May Contribute to Age-Related Muscle Decline

Aging-US

Play Episode Listen Later Jun 3, 2026 4:30


BUFFALO, NY — June 3, 2026 — A new #research paper was #published in Volume 18 of Aging-US on May 15, 2026, titled “Extracellular vesicles released by senescent myoblasts affect recipient cells via miRNA-target interactions.” The study was led by first author Michael Kamal from the Department of Kinesiology at McMaster University and corresponding author Gianni Parise from the same university. As people age, skeletal muscle gradually loses strength, size, and regenerative capacity. Scientists have increasingly linked these changes to cellular senescence—a state in which damaged cells permanently stop dividing but remain metabolically active. These senescent cells release a complex mixture of signaling molecules known as the senescence-associated secretory phenotype (SASP), which can influence neighboring cells and contribute to tissue dysfunction. In this study, the researchers investigated whether extracellular vesicles (EVs)—tiny membrane-bound particles released by cells—play a role in this process. Specifically, they examined EVs released by senescent muscle precursor cells, known as myoblasts, and analyzed the microRNAs (miRNAs) carried within these vesicles. The team found that senescent myoblasts released factors that impaired normal muscle cell development. When healthy muscle cells were exposed to signals from senescent cells, the resulting muscle fibers became significantly smaller and displayed increased expression of genes associated with cellular stress and senescence. Further analysis revealed that EVs released by senescent myoblasts carried a distinct set of miRNAs. The researchers identified 22 significantly altered miRNAs, including several previously linked to cellular senescence, such as miR-34a, miR-34b, miR-34c, and miR-22. The study also identified miR-301a-3p as a potentially novel senescence-associated miRNA. Full press release - https://aging-us.net/2026/06/03/senescent-muscle-cells-send-molecular-messages-that-may-contribute-to-age-related-muscle-decline/ DOI - https://doi.org/10.18632/aging.206379 Corresponding author - Gianni Parise - pariseg@mcmaster.ca Abstract video - https://www.youtube.com/watch?v=HKBbraYg8ew Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206379 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, cellular senescence, extracellular vesicles, myoblasts, miRNA, multi-omics To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

The Negotiation
From Abstract Models to Ground Truth: Eric Stryson on Operating Credibly in Asian Markets

The Negotiation

Play Episode Listen Later Jun 2, 2026 54:49


Most global businesses enter Asia with a playbook built elsewhere. The pricing models, growth assumptions, labour structures, and definitions of value that worked in North America or Europe get applied to markets that operate by fundamentally different rules. The result, as Eric Stryson has observed across nearly two decades of on-the-ground leadership work in Asia, is failure - not dramatic failure, but the slow erosion of credibility that comes from never truly understanding where you are.Eric Stryson is Managing Director at The Global Institute For Tomorrow (GIFT), an independent pan-Asian think tank with offices in Hong Kong and Kuala Lumpur. He has designed and facilitated more than 60 experiential leadership programmes across fifteen countries in Asia and the Middle East, working with over 3,000 executives from organisations including HSBC, Petronas, Marriott, MasterCard, and Standard Chartered. His public sector clients include the Hong Kong SAR Government, the Dubai Government, and the Central Bank of Malaysia.In this episode, Eric argues that much of what organisations believe they know about Asia is filtered through AI systems, research, and analysis shaped by Western institutions and historical precedents. Even conventional online research surfaces insights produced predominantly by incumbent Western policy and academic bodies, reinforcing a narrow and often distorted lens. Challenging these assumptions, he contends, requires moving beyond second-hand analysis and grounding decision-making in on-the-ground observation and lived experience.From renegotiating what 'value' means to understanding why Western growth models break down in Asia's diverse political and social contexts, Eric offers a rare perspective on what it actually takes to operate credibly in a post-Western, Asia-led growth environment. Discussion Points·       Why Western-filtered research and AI-generated analysis fail businesses trying to understand Asian markets·       Concrete examples of Western business models and assumptions breaking down on the ground in Asia·       How Asian markets define value differently - and why pricing strategies built elsewhere so often misfire·       Why 'scale fast, dominate markets' growth assumptions need renegotiating in Asia's diverse contexts·       What nearly 20 years of field project work in Asia reveals that research reports and case studies don't·       How consumption patterns and labour structures in Asia require businesses to rethink core operating models·       What 'post-Western world' means in practice for businesses operating in China, Southeast Asia, and the Middle East·       How to use AI tools responsibly when the training data reflects predominantly Western institutional perspectives·       Why Hong Kong businesses face an urgent reinvention moment - and what that looks like in practice·       The single most important thing Western businesses should do differently before entering or scaling in Asian marketsGuest BioEric Stryson is Managing Director at The Global Institute For Tomorrow (GIFT), an independent pan-Asian think tank with offices in Hong Kong and Kuala Lumpur. He has designed and facilitated more than 60 experiential leadership programmes across fifteen countries in Asia and the Middle East, working with over 3,000 executives from C-suite to high-potential talent. His corporate clients include AIA, BASF, CITIC, DBS, FedEx, HSBC, Marriott, MasterCard, Panasonic, Petronas, Prudential, and Standard Chartered. His public sector clients include the Hong Kong SAR Government, the Dubai Government, the Central Bank of Malaysia, and various provincial and county governments in mainland China. Eric's articles have appeared in the South China Morning Post, Financial Times, China Daily, and The Straits Times, and he has been interviewed by CNBC. Links & Resources·       GIFT website: www.global-inst.com·       Eric Stryson profile: global-inst.com/team/eric-stryson·       SCMP: Reinvention must start now if Hong Kong businesses are to survive change·       FT Letter: A Bric in a de-dollarised wall or a new architecture?·       Digital Transformation Documentary: Eric Stryson on technology causing problems

Oncotarget
Protein in Tumor Microenvironment Found to Promote Colorectal Cancer Growth and Immune Evasion

Oncotarget

Play Episode Listen Later Jun 2, 2026 4:17


BUFFALO, NY – June 2, 2026 – A new #research paper was #published in Volume 17 of Oncotarget on May 20, 2026, titled “Microenvironmental CTHRC1 has a pro-tumorigenic role in colorectal cancer.” The study was led by first author Haylee Duval from the Center for Molecular Medicine at the MaineHealth Institute for Research and the Graduate School of Biomedical Science and Engineering at the University of Maine. The study's corresponding authors were Sergey Ryzhov, Volkhard Lindner, and Michaela R. Reagan, who are affiliated with the Center for Molecular Medicine at the MaineHealth Institute for Research, the Graduate School of Biomedical Science and Engineering at the University of Maine, and Tufts University School of Medicine. Colorectal cancer remains one of the leading causes of cancer-related deaths worldwide. While much research has focused on cancer cells themselves, growing evidence suggests that the tumor microenvironment—the network of surrounding stromal cells, immune cells, and extracellular components—plays a critical role in determining how tumors grow and spread. In this study, researchers investigated collagen triple helix repeat containing 1 (CTHRC1), a secreted protein previously associated with poor outcomes in several cancer types. Although CTHRC1 is frequently detected in tumor-associated stroma, its precise role within the colorectal cancer microenvironment has remained unclear. To address this question, the team used a genetically engineered mouse model lacking CTHRC1 and compared tumor development with that of normal mice after colorectal cancer cells were introduced. The results consistently showed that the absence of host-derived CTHRC1 significantly reduced tumor growth. Across three independent experimental cohorts, mice lacking CTHRC1 developed substantially smaller tumors than their normal counterparts. In addition, survival improved markedly. The median survival of mice with normal CTHRC1 expression was 28 days after tumor inoculation, compared with 69 days in CTHRC1-deficient mice. The researchers also found evidence that CTHRC1 influences anti-tumor immunity. Mice lacking CTHRC1 had higher percentages of CD3-positive T cells in both tumors and spleens, suggesting a more active immune response against cancer. At the same time, they exhibited reduced levels of certain myeloid immune cells associated with immune suppression. Importantly, the investigators confirmed that the colorectal cancer cells themselves did not produce detectable CTHRC1. Instead, the protein was found primarily in fibroblasts and other stromal components surrounding the tumor. This finding indicates that the tumor-promoting effects originated from the tumor microenvironment rather than from the cancer cells directly. Histological analyses further revealed striking differences in tumor structure. Tumors from CTHRC1-deficient mice contained fewer cells and showed evidence of regression, while tumors in normal mice remained densely cellular and continued to expand. Full press release - https://www.oncotarget.com/news/pr/protein-in-tumor-microenvironment-found-to-promote-colorectal-cancer-growth-and-immune-evasion/ DOI - https://doi.org/10.18632/oncotarget.28878 Correspondence to: Sergey Ryzhov - Sergey.Ryzhov@mainehealth.org; Volkhard Lindner- Volkhard.Lindner@mainehealth.org; Michaela R. Reagan - Michaela.Reagan@mainehealth.org Abstract video - https://www.youtube.com/watch?v=gTbYy6vGd7E To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Takeaway Chinese
Special: How to say "abstract 抽象" in Chinese?

Takeaway Chinese

Play Episode Listen Later May 29, 2026 1:17


In this special episode of Takeaway Chinese, we're going to learn how to say "abstract" in Chinese.

The Partial Historians
The Emperor Julian with Jeremy Swist

The Partial Historians

Play Episode Listen Later May 28, 2026 64:39


The Emperor Julian with Jeremy SwistWe are thrilled to welcome Assistant Professor Jeremy Swist back to the show to discuss all things emperor Julian! Julian's rule as Roman emperor was short, but it also created quite a stir because Julian was keen to turn Rome away from Christianity and to bring back the paganism. How did he do it? Why did he do it? And what's the legacy that he left behind? We consider the details.Jeremy Swist has a PhD in Classics from the University of Iowa, and his research interests include imperial Greek and Roman historiography and rhetoric, late antiquity, classical reception in heavy metal music. He is currently Assistant Professor of Classical Studies at Michigan State University. Jeremy has published and presented extensively, and he has a particular interest in the intersection of heavy metal music and the classical world - we suggest you check out his blog, Heavy Metal Classicist, or our previous episode with him to find out more. In 2024, he translated and produced a dramatic reading of the Emperor Julian's Symposium of the Caesars, which starred some of the finest podcasters and actors in the WORLD! (Maybe us)The Emperor Julian, who ruled Rome between 361 and 363 CE, is one of Jeremy's great passions, and we are thrilled to talk to him about his new volume on this unusual ruler. The book is published by Oxford University Press and is entitled Julian Augustus: Platonism, Myth, and the Refounding of Rome.Abstract from Oxford University Press“The Roman emperor Julian employed both words and deeds to return the empire to paganism and reverse Christianization, inspired by his conversion to the Neoplatonic philosophy and radical pagan Hellenism of Iamblichus, and promoted by his own production of Greek literature. These works present a coherent vision of the providentially guided history and destiny of Rome as a series of (re)foundations enacted by rulers such as Romulus, Numa, and Augustus. Julian offers an Iamblichean approach to interpreting Roman legends, Platonic allegories, and myths of his own creation to articulate his own role in the refounding of the empire. Approaching the wider examination of Julian's imperial self-image on these terms ends up nuancing and challenging common assumptions influenced by the rhetoric of his contemporary proponents. In his reverence for the gods and for philosophy, the emperor's self-construction embraces the identities of a statesman and solider more than philosopher, Roman more than Greek, and mere human rather than semi-divine being. Julian's unique positionality as emperor let him invert the conventions of panegyric whereby rulers equal and surpass the demigods and heroes of myth and history. While distancing himself from the ideal models of virtue and founding that inspire him, he adopts a different set of exemplary figures as mirrors of himself. Statesmen such as Pericles and Scipio, and especially Augustus, serve as precedents for Julian's more realistic conception of his role in refounding the empire, as student and champion of philosophers, guardian of law and tradition, and servant of the gods.”The return to the old godsJulian's rule was short but it left quite an impact. We chat with Jeremy about some of the ideas Julian put forward about Rome, the foundation stories that underpinned its self-definition, and what might have been if weren't for an unfortunate spear that wounded Julian and ended his life just two years into his reign.Sound CreditsOur music is by the superb Bettina Joy de Guzman.For our full show notes and edited transcripts, head on over to https://partialhistorians.com/Support the showPatreonKo-FiRead our booksRex: The Seven Kings of RomeYour Cheeky Guide to the Roman Empire Hosted on Acast. See acast.com/privacy for more information.

Achtsam - Deutschlandfunk Nova
Akzeptanz - Ein Ja zum Nein

Achtsam - Deutschlandfunk Nova

Play Episode Listen Later May 27, 2026 38:36


Das Leben läuft oft anders als erhofft: Trennung, Krankheit oder Enttäuschungen werfen uns aus der Bahn. In dieser "Achtsam" klären wir, wie wir uns schmerzenden Gefühlen nähern und warum Akzeptanz uns wieder handlungsfähig machen kann.**********Quellen aus der Folge:Abstract zu: Aldao, A., Nolen-Hoeksema, S., & Schweizer, S. (2010). Emotion-regulation strategies across psychopathology: A meta-analytic review. Clinical psychology review, 30(2), 217-237.Abstract zu: Witvliet, C. V. O., Ludwig, T. E., & Laan, K. L. V. (2001). Granting forgiveness or harboring grudges: Implications for emotion, physiology, and health. Psychological science, 12(2), 117-123.Witvliet, C. V. O., Ludwig, T. E., & Laan, K. L. V. (2001). Granting forgiveness or harboring grudges: Implications for emotion, physiology, and health. Psychological science, 12(2), 117-123.**********Mehr zum Thema bei Deutschlandfunk Nova:Akzeptanz und Psyche: Einfach mal wahrnehmenStimmungsbarometer: Wie Moodtracking uns helfen kannAkzeptanz- und Commitment-Therapie: Partnerschaften achtsam gestalten**********Den Artikel zum Stück findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .**********Ihr habt Anregungen, Ideen, Themenwünsche? Dann schreibt uns gern unter achtsam@deutschlandfunknova.de

NeuroEdge with Hunter Williams
Peptides and Cancer | 20+ Studies the Critics Won't Show You

NeuroEdge with Hunter Williams

Play Episode Listen Later May 22, 2026 30:08


All links here: ⁠https://hunterwilliamshealth.com/linksTimestamps:00:00 Intro01:00 Why I'm making this video04:00 The plan: peptides with direct anti-cancer evidence06:02 AOD-9604 and HGH Frag 176-19107:42 BPC-15709:54 DSIP (Delta Sleep Inducing Peptide)11:08 Epitalon12:30 Follistatin 34413:30 GHK-Cu14:36 Kisspeptin15:58 KPV17:18 LL-3718:46 Melanotan 219:58 MOTS-c21:12 Retatrutide22:34 Semaglutide23:40 SS-3124:38 Thymalin25:26 Thymosin Alpha-127:00 Tirzepatide27:30 VIP (Vasoactive Intestinal Peptide)28:06 Bottom line and closing thoughtsDescriptionIf you spend any time in the peptide social media world, you've heard it. "Peptides cause cancer." It's the easiest way to scare someone off something, and a lot of people do it without ever showing you a single study.So I went and pulled the studies. In this video I walk through every peptide on the popular research peptide list that actually has direct anti-cancer evidence in the published literature. Not theory. Not mechanism guesses. Actual studies in cells, animals, and in some cases, humans.You'll see what the research says about BPC-157, GHK-Cu, Epitalon, KPV, LL-37, Thymosin Alpha-1, MOTS-c, semaglutide, tirzepatide, retatrutide, and a handful more. Some of this evidence is strong. Some is preliminary. I'm honest about both.This is not medical advice and I'm not telling you peptides cure cancer. That's not what the data says and that's not what I'm claiming. What I am saying is that the next time someone hits you with a 60 second clip telling you peptides cause cancer, you'll have something more substantial to weigh it against.All study links below.

LearnCraft Spanish
74: Nombre, tipo, historia, and other Spanish abstract nouns

LearnCraft Spanish

Play Episode Listen Later May 21, 2026 21:36


Let's practice some common Spanish abstract nouns, including nombre, tipo, historia, and poco. Practice all of today's Spanish for free at LCSPodcast.com/74

TechCrunch Startups – Spoken Edition
Status AI raises $17M to turn social media into interactive entertainment; plus, Stilta helps companies rediscover the patents they forgot they had

TechCrunch Startups – Spoken Edition

Play Episode Listen Later May 20, 2026 8:51


Interactive social media site Status announced Tuesday $17 million in combined seed and Series A funding, with investors including General Catalyst, YC, LightShed Ventures, and Abstract. Also, Stilta announced Tuesday a $10 million seed round led by Andreessen Horowitz. Other investors in the round include YC and operators from companies like OpenAI, Legora, and Lovable. Learn more about your ad choices. Visit podcastchoices.com/adchoices

BCI Cattle Chat
After the Abstract: How does bovine leukosis affect cow-calf herds

BCI Cattle Chat

Play Episode Listen Later May 19, 2026 23:48


In this episode of Diving Into Diets on Bovine Science with BCI, Dr. Brad White and Dr. Todd Gunderson discuss a 2026 study on the high prevalence of bovine leukemia virus in cow-calf operations, implications for cow reproduction, culling, and calf weight. The conversation concludes there is not a great association between culling risk and pregnancy status associated with the ELISA test. Read the article here

Open Line, Monday
Catholic Church Softening Sexual Morality?

Open Line, Monday

Play Episode Listen Later May 18, 2026 50:29


Where Peter is? Turning your son in to justice? Abstract religion? Join us for Open Line Monday with Fr. John Trigilio.

Wikipediapodden
Abstract Wikipedia, James Forrester – #368

Wikipediapodden

Play Episode Listen Later May 16, 2026 28:42 Transcription Available


This is a special episode about Abstract Wikipedia with James Forrester, Principal Software Engineer and Tech Lead for Abstract Wikipedia, Wikimedia Foundation. We refer to the previous episode about Abstract Wikipedia. All episodes in English (podcast feed) Credits The music and sound clips are from Surf Shimmy by Kevin MacLeod (incompetech.com) [CC BY 3.0], via Wikimedia Commons. Image: Abstract-Wikipedia-favicon.svg, Wikimedia Foundation, Public domain. Discuss the episode on the project’s talk page. The episode is also available on Wikimedia Commons.

Tenet
Ep. 205 Jes Moran – Abstract Painter using machine-sewn textile processes

Tenet

Play Episode Listen Later May 14, 2026 182:59


This week, Wes and Todd talk with Colorado Springs Artist, Jes Moran. Jes discusses her engagement with art as a child, growing up in Wisconsin, altering clothes & studying apparel design, her compulsion to make, loving process, having an intentional art practice the past five years, creative ideas, some of the other creative pursuits that she explored before doing the work she does now, being self-taught, learning to trust herself, her process, being fearless, quilts, sewing, what art does for her, letting go, her older work, titles, negative space, abstract art, experimentation & exploration, finding her voice, writing, space, memories, family, vulnerability, self-doubt, routine, sacrifices, potato chips, color, her new work, her show at Auric in June, being seen & valued, the support of her family, the Colorado Springs art community, and her idea of perfect happiness.Join us for a wonderful conversation with Jes Moran!Check out Jes Moran's exquisite work at www.jesmoran.comFollow Jes Moran on social media:Instagram - www.instagram.com/jesdmoran/ - @jesdmoranJes' exhibition “Seam Shift: painting through construction” will be on display at Auric Gallery through the month of June. Opening reception June 5th.  For more information go to www.auricgallery.comSend us Fan MailFollow us on Instagram:@tenetpodcast - www.instagram.com/tenetpodcast/@wesbrn - www.instagram.com/wesbrn/@toddpiersonphotography - www.instagram.com/toddpiersonphotography/ Follow us on Facebook:www.facebook.com/TenetPodcast/Email us at todd@toddpierson.com If you enjoyed this episode or any of our previous episodes, please consider taking  a moment and leaving us a review on your favorite podcast platform.Thanks for listening! 

Geek Psychology: Play Life Better
Mistakes Most INFPs Make With ISTJs That Ruin The Relationship

Geek Psychology: Play Life Better

Play Episode Listen Later May 13, 2026 17:40


Most communication is misunderstood by default.I break down why INFPs and ISTJs keep missing each other even when they care deeply, and what you can actually do to fix it. If you've ever felt like your partner just doesn't “get” you, this will clarify what's happening under the surface.In this video, I go into how communication gets filtered through personal meaning, why abstract ideas and feelings often get distorted, and how cognitive functions create friction in relationships. I also show how INFPs can adjust their approach without betraying themselves.You'll learn:Why “understanding” is often an illusionHow INFP and ISTJ functions clash in communicationWhat role assumptions and mind-reading playHow to use feedback and clarity to reduce conflictA simple shift using your tertiary functionThe exact question that cuts through confusionIf you want better communication, less frustration, and more alignment in your relationship, this gives you a practical way forward.If this helped, subscribe for more on personality, relationships, and leveling up your inner characters.Like the video if you've experienced this. It helps more people see it.Drop a comment with your experience. INFP, ISTJ, or something else.0:00 Most communication is miscommunication0:32 Why your words get interpreted differently1:28 Abstract ideas always get distorted2:15 Stop assuming they understand you3:05 Mind reading is breaking your relationship4:05 Take responsibility for being understood5:05 INFP cognitive functions (Soul, Explorer)6:35 ISTJ cognitive functions (Guardian, Commander)8:10 Why INFP vs ISTJ naturally clash9:45 Why your advice feels wrong to them11:20 Why their advice feels wrong to you12:45 The “function mismatch” problem13:40 Fix #1: Use your Guardian (Si)14:40 Fix #2: Get specific and clarify15:40 The question that fixes misunderstanding

Silicon Curtain
1062. Don't Waste Your Empathy on Invaders - Abstract Sympathy is a Lethal Weapon!

Silicon Curtain

Play Episode Listen Later May 12, 2026 44:43


Artur Dron is a 25-year-old Ukrainian poet, essayist, and combat veteran. Born in Ivano-Frankivsk Oblast in western Ukraine. Graduated from the Department of Journalism at Ivan Franko National University of Lviv. Before the full-scale invasion, worked as event manager at The Old Lion Publishing House in Lviv — the publisher that would later issue Hemingway Knows Nothing. Saw combat across Donetsk, Kharkiv, and Zaporizhzhia oblasts. Seriously wounded in October 2024 by an anti-personnel mine. Endured multiple surgeries and a nerve transplant after shrapnel injuries. Demobilised in July 2025 due to disability — discharged on 4 July 2025, completing service that began on 2 March 2022. His poetry has been translated into at least ten languages.----------BOOKS: Dormitory №6 (2020) We Were Here (2023)Hemingway Knows Nothing (2025)LINKS:https://warpoetryukraine.org/https://pen.org.ua/en/members/dron-arturhttps://ukraineworld.org/en/articles/stories/poetry-ukrainianhttps://chytomo.com/en/review-of-artur-dron-s-book-hemingway-knows-nothing/https://www.arrowsmithpress.com/journal/artur-dronhttps://book.artarsenal.in.ua/en/guest-2023/artur-dron-2/To purchase Artur's book of poetry in UK: https://www.jantarpublishing.com/product-page/we-were-here----------SUPPORT THE CHANNEL:https://www.buymeacoffee.com/siliconcurtainhttps://www.patreon.com/siliconcurtainhttps://www.gofundme.com/f/scaling-up-campaign-to-fight-authoritarian-disinformation----------ACTIVE CAMPAIGN:We are raising funds for 5 of 15 Vampire DronesSilicon Curtain for Kupiansk Vampires. Dzyga's Paw, together with Jonathan Fink, is joining forces to raise $40,000 to provide the Khartiia Brigade with Vampire Drones.https://dzygaspaw.com/silicon-curtain-for-kupiansk-vampiresThese heavy bombers are designed to destroy manpower and equipment, as well as for remote mining. The Vampire UAV, manufactured by Skyfall, has proven itself to be one of the most effective weapons in the Kupiansk direction. Skyfall is one of Ukraine's largest defense tech companies, producing Vampire bomber drones, various modifications of Shrike FPV drones, P1-SUN, Shahed drone interceptors, communication systems, and components.https://dzygaspaw.com/silicon-curtain-for-kupiansk-vampires----------TRUSTED CHARITIES ON THE GROUND:Car4Ukrainehttps://car4ukraine.com/en-US/campaignsDzyga's Pawhttps://dzygaspaw.com/projectsSuperhumans - Hospital for war traumashttps://superhumans.com/en/UNBROKEN - Treatment. Prosthesis. Rehabilitation for Ukrainians in Ukrainehttps://unbroken.org.ua/Come Back Alivehttps://savelife.in.ua/en/Chefs For Ukraine - World Central Kitchenhttps://wck.org/relief/activation-chefs-for-ukraineUNITED24 - An initiative of President Zelenskyyhttps://u24.gov.ua/Serhiy Prytula Charity Foundationhttps://prytulafoundation.orgNGO “Herojam Slava”https://heroiamslava.org/----------PLATFORMS:Substack: https://substack.com/@siliconcurtainTwitter: https://twitter.com/CurtainSiliconLinkedin: https://www.linkedin.com/in/finkjonathan/Podcast: https://open.spotify.com/show/4thRZj6NO7y93zG11JMtqm----------

Song Talk Radio | Songwriting Tips | Lyrics | Arranging | Live Feedback
Spinning real life into an abstract song with Avril Jensen

Song Talk Radio | Songwriting Tips | Lyrics | Arranging | Live Feedback

Play Episode Listen Later May 12, 2026 31:50


We chatted with Montreal-based artist Avril Jensen about writing an abstract song from personal experience. Download the lyrics to Dog (everybody learns) to follow along. We talked about: Songwriting Challenge 2026: Write a Traditional Country Song Writing musically interesting melodies that are still catchy Writing the lyrics based on personal experience with actual dogs, but maybe it's also a metaphor for a toxic relationship 80s French Canadian band The Box Does music theory get in your way of keeping things simple?… Read the rest

Shaun Newman Podcast
#1049 - Peter Kirby

Shaun Newman Podcast

Play Episode Listen Later May 7, 2026 84:29


Peter A. Kirby is a world-renowned independent researcher, investigative author, and activist specializing in deep dives into suppressed and controversial subjects. His groundbreaking work on geoengineering and weather modification has earned him international recognition. Peter is the author of "Chemtrails Exposed: A New Manhattan Project", widely regarded as the most comprehensive book on the subject. He hosts The Abstract on Rumble and provides sharp social commentary on TruthSocial. His research has been translated into every major language and featured across major alternative media platforms.Watch the Cornerstone Forum 26'https://shaunnewmanpodcast.substack.com/Silver Gold Bull Links:Website: https://silvergoldbull.ca/Email: SNP@silvergoldbull.comText Grahame: (587) 441-9100Bow Valley Credit UnionBitcoin: www.bowvalleycu.com/en/personal/investing-wealth/bitcoin-gatewayEmail: welcome@BowValleycu.com Get your voice heard: Text Shaun 587-217-8500

Circles Off - Sports Betting Podcast
NCAA Betting Scandal • Prediction Market Truth • Parlay Myths

Circles Off - Sports Betting Podcast

Play Episode Listen Later May 1, 2026 70:33


This episode covers a wide range of topics across betting, prediction markets, and probabilistic thinking. We start with the Brendan Sorsby situation after reports surfaced about a major gambling-related issue involving the Texas Tech QB, including over 10,000 bets placed dating back to 2022. The conversation focuses on what this means for gambling integrity in college sports and the broader responsibility discussion that comes with it. From there, the panel reacts to Isaac Rose-Berman's recent article on prediction markets and the way they are positioned as an alternative to traditional sportsbooks. The discussion explores whether that framing is accurate, how these platforms actually generate profit, and what bettors often misunderstand about their structure. The group also breaks down a viral take from Plus EV Analytics on parlay thinking and how human intuition struggles with probability when outcomes are layered together. Host Jacob Gramegna is joined throughout the episode by Joey Knish, Isaac Rose-Berman, and Chris Dierkes (Flupnolide), a trader at Novig, with all four contributors involved in the full discussion across gambling, markets, and bettor psychology.

Oncotarget
Targeted Therapies Drive Long-Term Decline in Multiple Myeloma Mortality in the U.S.

Oncotarget

Play Episode Listen Later Apr 29, 2026 3:23


BUFFALO, NY – April 29, 2026 – A new #research paper was #published in Volume 17 of Oncotarget on April 28, 2026, titled “Targeted therapeutics and U.S. population-level mortality trends in multiple myeloma: A SEER-based analysis from 1975 to 2023.” The study was led by first and corresponding author Navkirat Kahlon from the Mass General Cancer Center at Wentworth-Douglass Hospital, in collaboration with researchers from multiple U.S. institutions. In this study, the researchers examined how mortality trends in multiple myeloma have changed in the United States over nearly five decades, using population-level data from the SEER database. Multiple myeloma, a cancer of plasma cells, has historically been associated with poor survival outcomes, but treatment options have evolved dramatically over time. The analysis revealed a clear shift in mortality trends that closely parallels major therapeutic advances. Between 1975 and the mid-1990s, mortality rates steadily increased, reflecting the limited effectiveness of early treatments such as alkylating agents and corticosteroids. A turning point emerged in the 1990s with the introduction of autologous stem cell transplantation, which marked the first meaningful improvement in survival outcomes. Over the following years, the development of targeted therapies—including immunomodulatory drugs and proteasome inhibitors—was associated with a more pronounced decline in mortality. These treatments introduced new mechanisms of action, such as immune modulation and enhanced cancer cell apoptosis, significantly improving disease control. More recent years have seen further progress with the introduction of monoclonal antibodies, maintenance therapies, and combination treatment strategies. Notably, the steepest decline in mortality occurred between 2021 and 2023, coinciding with the clinical adoption of advanced immunotherapies such as CAR T-cell therapies and bispecific antibodies. These treatments have shown the ability to induce deep and durable responses, even in heavily pretreated patients. “Our findings highlight the real-world impact of targeted therapies on population-level outcomes and underscore the urgent need for care models that ensure accessibility, affordability, and long-term sustainability in the era of precision oncology.” Importantly, while these therapeutic advances have improved survival, they have also introduced new challenges. Many patients now require long-term treatment, which can be associated with cumulative toxicities and a significant financial burden. In addition, access to these therapies remains uneven, influenced by geographic, socioeconomic, and healthcare system factors. Overall, this study provides a comprehensive, real-world view of how advances in cancer treatment have translated into measurable improvements in survival at the population level. At the same time, it highlights the need to ensure that these benefits are both sustainable and accessible to all patients as the field continues to evolve. DOI - https://doi.org/10.18632/oncotarget.28877 Correspondence to - Navkirat Kahlon - nkahlon@mgb.org; (ORCID: https://orcid.org/0000-0003-1115-2029) Abstract video - https://www.youtube.com/watch?v=-TNWkG9FyUo Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us on social media: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

ASGCT Podcast Network
ASGCT 2026 Abstract Highlights with Emily Walsh Martin, Sanjay D'Souza, and Jason West

ASGCT Podcast Network

Play Episode Listen Later Apr 27, 2026 43:06


Join host Emily Walsh Martin, PhD, as she hands the baton to the new co-hosts of The Issue podcast, Sanjay D’Souza, PhD, and Jason West, PhD. Listen in as the three preview some of the abstracts that will be presented at the ASGCT 2026 Annual Meeting, held May 11-15 in Boston, MA. Music: ‘Bright New Morning’ by Steven O’Brien – released under CC-BY 4.0. https://www.steven-obrien.net/Show your support for ASGCT!: https://asgct.org/membership/donateSee omnystudio.com/listener for privacy information.

Maverick Podcast
The Transformation Of Robin Marsh: From News Icon To Abstract Artist // Maverick Podcast

Maverick Podcast

Play Episode Listen Later Apr 27, 2026 76:57


Most stories of success involve resilience, faith, and a little bit of daring, and Robin Marsh's journey proves it. From a small-town girl with big dreams to a beloved news anchor and abstract artist, Robin's life is a masterclass in authenticity and purpose.Maverick Podcast // Episode 173Robin Marsh:https://www.robinmarshdesigns.comhttps://www.instagram.com/robinmarshokhttps://www.tiktok.com/@robinmarsh86Maverick Podcast:

Application Paranoia
AP_EP87 Platform vs Precision — Is Security Getting Simpler or Just More Abstract?

Application Paranoia

Play Episode Listen Later Apr 27, 2026 33:14 Transcription Available


Send us Fan MailIn Episode 87 of Application Paranoia, Colin Bell is joined by Rob Cuddy and Kris Duer to unpack the industry's growing push toward security platform consolidation.Are customers really asking for fewer tools, or are vendors shaping the narrative? Is consolidation improving security outcomes, or simply making complexity easier to explain to executives, boards, and auditors?The team also discusses AI-generated code, customer questions from the field, SAST analysis choices, data flow, false positives, and Kris's take on AI fear-based marketing.Plus: NPC streaming, Second Life hacking nostalgia, golf season, proactive SCA monitoring, and a quick preview of Colin and Kris's upcoming webinar on AI-assisted development.Webinar: Join Colin and Kris on 6 May for a discussion on how AI is changing how code gets written, trusted, validated, and approved. Register here: https://www.linkedin.com/events/7449460461881704448/

Spear Gored Radio
20 April 2026

Spear Gored Radio

Play Episode Listen Later Apr 21, 2026 63:37


The Fall "U.S. 80s-90s" (Live) Drome "Moon On My Screen" (Dub Version) Autechre "P.I.O.B." (Mix Two) Faust "Right Between Yr Eyes" Stereolab "Percolations" Foetus "Herds" Pumice "Weird Crab Holy Soldier" John Fahey "Ghosts" The Microphones "Mount Eerie" Ksiezyc "Zakopana" Celtic Frost "Caress Into Oblivion" Scott Walker & Sunn O))) "Fetish"

Federal Drive with Tom Temin
Congress is often treated like an abstract institution, but it's also a workplace, with real security pressures and family realities

Federal Drive with Tom Temin

Play Episode Listen Later Apr 20, 2026 14:13


Behind the scenes on Capitol Hill, concerns about personal safety, logistics and family well‑being shape how members and staff experience the job day to day. We'll take a practical look at how those very human factors affect focus, capacity, and the ability to do sustained legislative work. Danielle Stewart from the POPVOX Foundation joins me.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

General Nerdery
#219: Mindf***ers, Inc. - Absolute Martian Manhunter vol. 1

General Nerdery

Play Episode Listen Later Apr 19, 2026 68:20


Things get real heady in the studio as Your Generals try to take on the sad weirdness of ABSOLUTE MARTIAN MANHUNTER by Deniz Camp and Javier Rodriguez. Check out all General Nerdery Presents... podcasts at www.gnpresents.com Email us at generalnerderypod@gmail.com

Research To Practice | Oncology Videos
Lung Cancer — 5-Minute Journal Club with Dr Natalie Vokes: Current and Future Role of Tumor-Informed Circulating Tumor DNA Assays

Research To Practice | Oncology Videos

Play Episode Listen Later Apr 17, 2026 27:12


Featuring an interview with Dr Natalie Vokes, including the following topics: Perioperative minimal residual disease (MRD) detected by circulating tumor DNA (ctDNA) testing in patients with lung cancer (0:00) Ohara S et al. Clinical significance of perioperative MRD detected by ctDNA in patients with lung cancer with a long follow-up data: An exploratory study. JTO Clin Res Rep 2024;6(3):100762. Abstract Masuda K et al. MRDSEEKER (JCOG2111A): A prospective study to evaluate MRD and its association with prognosis in curative-intent NSCLC. World Conference on Lung Cancer 2025;Abstract P3.18.04.  Zhou C et al. IMpower010: Biomarkers of disease-free survival in a phase 3 study of atezolizumab vs best supportive care after adjuvant chemotherapy in stage IB-IIIA NSCLC. ESMO IO 2021;Abstract 2O. MRD analysis of adjuvant therapy with osimertinib for resected EGFR-mutated Stage IB to IIIA non-small cell lung cancer (NSCLC) (8:28) Herbst RS et al. Molecular residual disease analysis of adjuvant osimertinib in resected EGFR-mutated stage IB-IIIA non-small-cell lung cancer. Nat Med 2025;31(6):1958-68. Abstract MRD analyses of perioperative chemoimmunotherapy for resected NSCLC (15:12) Forde PM et al. Overall survival with neoadjuvant nivolumab plus chemotherapy in lung cancer. N Engl J Med 2025;393(8):741-52. Abstract  ctDNA dynamics in advanced NSCLC treated with immunotherapy (20:56) Vokes NI et al. Circulating tumor DNA (ctDNA) dynamics and survival outcomes in patients (pts) with advanced non-small cell lung cancer (aNSCLC) and high (>50%) programmed cell death ligand 1 (PD-L1) expression, randomized to cemiplimab (cemi) vs chemotherapy (chemo). ASCO 2023;Abstract 9022. Anagnostou V et al. ctDNA response after pembrolizumab in non-small cell lung cancer: Phase 2 adaptive trial results. Nat Med 2023;29(10):2559-69. Abstract Anagnostou V et al. A biomarker-directed, multi-center phase II/III study of ctDNA molecular response adaptive immuno-chemotherapy in patients with non-small cell lung cancer (BR.36). ASCO 2025;Abstract TPS8669. CME information and select publications

Oncotarget
Cancer Care in Conflict Zones Remains Critically Neglected

Oncotarget

Play Episode Listen Later Apr 13, 2026 2:04


BUFFALO, NY – April 13, 2026 – A new #review was #published in Volume 17 of Oncotarget on March 31, 2026, titled “Cancer without borders: Policy frameworks for oncology care in humanitarian and conflict settings.” The study—led by corresponding author Pragnesh Parmar, along with Gunvanti Rathod from AIIMS Bibinagar, Telangana, India—brings together evidence from peer-reviewed studies, global health reports, and case examples from regions such as Gaza, Sudan, and Ukraine to examine the structural, ethical, and policy barriers limiting access to cancer care in humanitarian settings. Their findings show that oncology services are often excluded from emergency health priorities, resulting in delayed diagnosis, treatment interruptions, and reduced access to palliative care. The review further highlights that disrupted infrastructure, legal constraints, and fragmented policies disproportionately impact vulnerable populations—including women, children, and the elderly—who often present with advanced disease stages due to delays in care. “Addressing cancer in humanitarian contexts is not merely a technical challenge but a moral imperative.” The authors conclude that integrating oncology into humanitarian response frameworks is essential to ensure equitable access to care and improve outcomes for displaced populations. They emphasize the need for coordinated global strategies, including cross-border care models, tele-oncology, and policy reform, to address this critical gap in global health systems. DOI - https://doi.org/10.18632/oncotarget.28856 Correspondence to - Pragnesh Parmar - drprag@gmail.com; (ORCID: orcid.org/0000-0002-8402-8435) Abstract video - https://www.youtube.com/watch?v=zXlhIBZyJ6Q Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28856 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, cancer care, humanitarian crisis, tele-oncology, global health policy, oncology triage To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us on social media: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Research To Practice | Oncology Videos
CELMoDs for Multiple Myeloma — Microlearning Activity 2 with Dr Paul G Richardson

Research To Practice | Oncology Videos

Play Episode Listen Later Apr 11, 2026 24:54


Featuring perspectives from Dr Paul G Richardson, including the following topics: EXCALIBER-RRMM: A Phase III trial of iberdomide, daratumumab and dexamethasone for relapsed/refractory multiple myeloma (0:00) Lonial S et al. EXCALIBER-RRMM: A phase III trial of iberdomide, daratumumab, and dexamethasone in relapsed/refractory multiple myeloma. Future Oncol 2025;21(14):1761-9. Abstract  Phase III SUCCESSOR-1 and SUCCESSOR-2 studies evaluating mezigdomide-based regimens for relapsed/refractory multiple myeloma (8:24) Richardson PG et al. A phase III, two-stage, randomized study of mezigdomide, bortezomib, and dexamethasone (MeziVd) versus pomalidomide, bortezomib, and dexamethasone (PVd) in relapsed/refractory multiple myeloma (RRMM): SUCCESSOR-1. SOHO 2023;Abstract MM-372. Richardson PG et al. A phase 3, two-stage, randomized study of mezigdomide, carfilzomib, and dexamethasone (MeziKd) versus carfilzomib and dexamethasone (Kd) in relapsed/refractory multiple myeloma (RRMM): SUCCESSOR-2. ASCO 2023;Abstract TPS8070.  EMN26: A Phase II study of maintenance therapy with iberdomide after autologous stem-cell transplantation for newly diagnosed multiple myeloma (13:34) van de Donk NWCJ et al. Iberdomide maintenance after autologous stem-cell transplantation in newly diagnosed multiple myeloma: An update from the phase 2 EMN26 trial. ASH 2025;Abstract 101.  STOMP: A Phase I study of selinexor, mezigdomide and dexamethasone for patients with relapsed/refractory multiple myeloma who experienced relapse with or are ineligible for T-cell-redirecting therapy (24:53) Mo C et al. Selinexor, mezigdomide, and dexamethasone in patients with relapsed/refractory multiple myeloma who relapsed or are ineligible for T-cell–redirecting therapy: Stomp Phase 1 results. ASH 2025;Abstract 4010.  CME information and select publications

Dr. Chapa’s Clinical Pearls.
Livi Post-Sex Vaginal Device: Hmmmm

Dr. Chapa’s Clinical Pearls.

Play Episode Listen Later Apr 9, 2026 11:38


Livi by LiviWell is an FDA-cleared, single-use, soft polyurethane foam device designed to immediately absorb post-intercourse fluids (semen) to support vaginal health. Inserted like a tampon within 15 minutes post-coitus, it works in roughly 60 seconds to restore natural pH, helping to manage odor, dripping, and discomfort. Is this evidence-based? Listen in for details.1. https://www.biospace.com/press-releases/liviwell-secures-fda-clearance-for-livi-introducing-a-new-category-in-post-intercourse-vaginal-care#:~:text=Advertise-,LiviWell%20Secures%20FDA%20Clearance%20for%20Livi%2C%20Introducing%20a%20New%20Category,and%20other%20post%2Dintercourse%20fluids.2. Mngomezulu K, Mzobe GF, Mtshali A, et al. Recent Semen Exposure Impacts the Cytokine Response and Bacterial Vaginosis in Women. Frontiers in Immunology. 2021. 3. Abstract: ISSWSH/ISSM Joint Meeting 2025. Abstract citation ID: qdaf068.138 (155) SEMEN IS NOTTHEVAGINA'SFRIEND:ANOVEL POST-SEX TAMPON IMPROVES VAGINAL HEALTH PARAMETERS

Unjaded: Human Design for Intentional Entrepreneurs
207 Human Design, Business Decisions, and Blue Sparrow

Unjaded: Human Design for Intentional Entrepreneurs

Play Episode Listen Later Apr 6, 2026 21:51


This week on Unjaded, I'm pulling back the curtain on the opening of Blue Sparrow -- my new online resale shop -- and using it as a live case study in what it actually looks like to make decisions from your Human Design. Not the pretty, cleaned-up version. The real one.Because this decision took a year. One full year. And if you know anything about Manifesting Generators, you know how painful that is.We're going deep on:The emotional authority piece no one talks about -- what it means to "wait your wave" when you have more than one wave, and why one wave is almost never enough for a real decision. I walked through three emotional waves before Blue Sparrow made sense. And I'd do it again.Abstract circuitry and verbal processing -- if you go around the mulberry bush when you talk (or think, or plan), you may have abstract circuitry in your design. The 46-29 and 41-30 channels in my design mean I'm always pulling from past experience to create forward-facing insight. It's not a flaw. It's the circuitry doing its job.Your Human Design signature and your sales -- this is the part I did not expect. The moment I committed to opening Blue Sparrow, my Human Design business sales spiked. Not a coincidence. When you're satisfied (Generators and MGs), successful (Projectors), surprised and delighted (Reflectors), or at peace (Manifestors), your aura expands. You magnetize people to you. When you're frustrated, angry, bitter, or disappointed? You push them away. Full stop.Why I'm leaving the bricks and mortar -- nothing against my partner Lisa (whose undefined G Center means that location is absolutely right for her). But I'm a second line with a markets environment and an emotional authority. I felt unsettled in that space from early on. Normalizing the knowing -- even when it doesn't make logical sense -- is the work.The big rock planning method -- how I prioritized Blue Sparrow as my Q1 non-negotiable and let other things slide to make it happen. The online store opened March 25th with $7-8K in inventory and a lot of conviction.If you want to understand your own design deeply enough to make decisions like this -- with your body, not your head -- readings are still half price on the site. Grab yours herehttps://www.vickiedickson.com/human-design-readingBlue Sparrow Shop: bluesparrow.caFollow along on Instagram: @bluesparrowshopBook a Human Design Reading: https://www.vickiedickson.com/human-design-reading

Sermons from Grace Cathedral
The Abstract Cross - A Reflection for Good Friday

Sermons from Grace Cathedral

Play Episode Listen Later Apr 4, 2026 11:05


The Rev. Br. Richard Edward Helmer, Precentor Grace Cathedral, San Francisco, CA Friday, April 3rd, 2026, 3p Solemn Liturgy of Good Friday Isaiah 52:13-53:12 Hebrews 4:14-16, 5:7-9 Psalm 22:1-11 John 18:1-19:42

Asking Why
Episode 183: Dr. Shawn McNeil & Dr. Donard Dwyer | Unlocking Schizophrenia

Asking Why

Play Episode Listen Later Mar 27, 2026 56:45


This week Clint speaks with Dr. Shawn McNeil & Dr. Donard.  In this conversation they explore the latest research and clinical practices in psychiatry, focusing on schizophrenia, genetic testing, early detection, and the impact of AI on mental health.    Dr. Shawn McNeil hosts an Apple podcast, "Addiction Medicine: Beyond the Abstract" Addiction Medicine: Beyond the Abstract - Podcast - Apple Podcasts. A quarterly, interactive addiction journal club was discussed, paired with presentation Dr. McNeil discusses on his podcast. https://podcasts.apple.com/us/podcast/addiction-medicine-beyond-the-abstract/id1806152019   Biography Dr. Shawn McNeil is a physician and researcher at LSU Health Shreveport. He is a Clinical Assistant Professor in the Department of Psychiatry and Behavioral Medicine and serves as Program Director of the Psychiatry Residency Program and Director of Neuroinformatics Research. He is a diplomate of the American Board of Psychiatry & Neurology and is board-certified in General Psychiatry and Child & Adolescent Psychiatry. He completed his Psychiatry residency at LSU Health Shreveport and is a recipient of the Resident Recognition Award from the American Psychiatric Association (APA). He also completed his fellowship in Child & Adolescent Psychiatry at LSU Health, serving as chief resident of the program.   Clinically, Dr. McNeil practices at Louisiana Behavioral Health where he serves as Chief Medical Officer. He also supervises residents at the Ochsner LSU Health Ambulatory Care Center. His primary research is clinical in nature. He is Principal Investigator on a clinical trial (Apathy in Schizophrenia, Intra-Cellular Therapies, Inc.) at the LSU Health Psychiatry Research Clinic which is investigating the use of Lumateperone on motivation in patients with psychotic disorders. He previously worked on the Blüm Autism Study (sponsored by Curemark) and the Tapestry Autism Study (sponsored by Axial Therapeutics). He is also the Director of Clinical Research for the Louisiana Addiction Research Center.   Dr. McNeil serves as President of the Louisiana Psychiatric Medical Association (LPMA). He is on the editorial board of the Journal of Addiction Medicine (JAM) and is host of their podcast "Addiction Medicine: Beyond the Abstract". He is a 2018 recipient of the ASAM's Ruth Fox Memorial Endowment Scholarship. He has also served on the editorial board of the APA's American Journal of Psychiatry Resident's Journal and he has been recognized as a Fellow of the APA.   Dr. McNeil was previously a staff physician at the Overton Brooks VA Medical Center and treated veterans in the Post-Traumatic Stress Disorder Clinic. He continues to proudly serve as a Deputy Coroner of Caddo Parish, Louisiana.     Donard Dwyer, PhD Professor of Psychiatry and Behavioral Medicine   Biography Donard Dwyer received his BS degree in Psychology from Tulane University, a Master's degree in education (MEd) from the University of Rochester and his PhD from the University of Alabama at Birmingham (UAB). In addition, to holding positions as a Research Scientist at the Max-Planck Society laboratories in Würzburg, Germany and Director of Immunology at a Cambridge biotechnology company, Dr. Dwyer has spent 32 years in academic research at UAB and LSU Health Shreveport. He is currently professor of Psychiatry and Pharmacology, Toxicology and Neuroscience at LSU Health Shreveport. In addition, he is Vice-Chair for Research in the Department of Psychiatry.   His research interests range broadly from the evolution of protein ligand-receptor interactions, the electronic properties of amino acids and regulation of glucose transport in neurons to behavioral genetics of motivation and movement in C. elegans and the genetic basis for schizophrenia and neuropsychiatric disorders. He is currently focused on the role of insulin signaling pathways in regulation of motivation in “suicidal” worms and characterization of the genetic architecture of schizophrenia with mathematical approaches. Finally, his laboratory is searching for drugs that produce neuroenhancement in cultured neurons as potential treatments for an array of neuropsychiatric conditions.     Medical Trial: https://www.lsuhs.edu/departments/school-of-medicine/psychiatry-and-behavioral-medicine/research   Chapters 00:00 Introduction to the Podcast and Guests 02:27 Overview of Schizophrenia and Motivation Challenges 04:23 The New Drug Adalumid Teparone and Its Potential 07:50 Understanding Schizophrenia: Causes and Risk Factors 12:04 Genetics of Schizophrenia: Myths and Realities 16:20 Enrolling Patients in Clinical Trials 20:49 Genetic Testing and Personalized Medicine in Psychiatry 25:54 Early Signs of Psychosis in Children 30:50 Supporting Families and Community Resources 40:04 The Role of AI in Future Psychiatry 52:17 AI and the Risks of Artificial Relationships 56:35 Conclusion: Hope and the Future of Mental Health Care

The 5 Minute Basketball Coaching Podcast
Ep 1331 How Can You Cast a Vision That Players and Parents Will Actually Follow?

The 5 Minute Basketball Coaching Podcast

Play Episode Listen Later Mar 19, 2026 5:13


https://teachhoops.com/ Communicating your vision is the most important "Pre-Game" activity you will ever perform. A vision isn't just a list of goals; it is a vivid picture of a future that hasn't happened yet. If you can't describe exactly what your program will look like, sound like, and feel like in three years, you can't expect your players or community to buy in. To be effective, your vision must move from "Abstract" to "Observable." Instead of saying "We want to be a tough program," say "We will be the team that is first to the floor for every loose ball and the loudest team in the hallway before every tip-off." When you make the vision "visible," you give your athletes a specific standard to measure themselves against every single day. The second pillar of communication is "The Power of Repetition." A vision is not a "One-and-Done" speech at the parent meeting in November; it is a daily "drip." You must be the "Chief Reminding Officer" of your program. Every drill, every post-game talk, and every social media post should be filtered through your vision. If your vision is "Unselfish Excellence," then you must publicly celebrate the "Extra Pass" more than the "Crossover Layup." In the mid-season January grind, when fatigue sets in, the vision is the "Why" that keeps your players pushing through the "How." Use your TeachHoops member calls to "audit" your messaging: if you asked your 12th man what the program's vision is, could they answer you in ten seconds? Finally, you must master "The Art of the Individual Connection." While you cast a broad vision for the team, you must also communicate a "Micro-Vision" for every individual. Every player needs to know exactly how their unique "Role" contributes to the "Master Plan." When a player understands that their "bench energy" or their "defensive rebounding" is a vital organ in the body of the program, they find "Purpose in the Process." Utilize "Vision One-on-Ones"—short, 5-minute meetings where you paint a picture of who that player can become by the end of the season. By connecting their personal growth to the program's success, you create an unbreakable bond of "Shared Ownership" that lasts long after the final buzzer. Basketball vision, coaching leadership, program building, team culture, athletic leadership, high school basketball, youth basketball, basketball IQ, coach development, championship habits, "Trust Equity" in sports, coaching philosophy, character development, coach unplugged, teach hoops, basketball success, mental toughness, leadership standards, communication skills for coaches, organizational vision. SEO Keywords Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Research Like a Pro Genealogy Podcast
RLP 400: From Searcher to Researcher: Listener Takeaways from 400 Episodes

The Research Like a Pro Genealogy Podcast

Play Episode Listen Later Mar 9, 2026 45:57


In this celebratory episode of the Research Like a Pro podcast, Diana and Nicole highlight the incredible impact the RLP process has had on their listeners by sharing several inspiring success stories. They read comments from researchers, one of whom explains how the RLP workflows help them conquer imposter syndrome, and another who shares a journey from feeling overwhelmed as a beginner to pursuing accreditation. Multiple individuals note that the RLP method turned them from "searchers" into "researchers," providing the structure and discipline necessary to break down brick walls, and in one instance, even launch a genealogy business.  Nicole shares fun podcast statistics, including that all 400 episodes equate to 250 hours of continuous listening, and that the total downloads for each podcast episode are roughly equivalent to filling the home-side bleachers of a high school stadium. Diana and Nicole then summarize the core benefits listeners gain from applying the RLP process, which include overcoming overwhelm, building confidence to go from intermediate to professional, and staying motivated by connecting with peer groups. They conclude by discussing the profound purposes of family history, such as making new discoveries, uncovering the truth, and rescuing ancestors from anonymity, which ultimately helps listeners connect with the past and preserve their family's stories for future generations. Listeners learn how to be more productive and disciplined and how the RLP process provides the confidence and structure needed to advance their genealogical research. This summary was generated by Google Gemini. Links Episode 1 from seven and a half years ago, July 16, 2018 - https://familylocket.com/rlp-1-introduction/ Top Ten Most Downloaded Episodes of RLP RLP 185: Revisiting Timelines and Analysis Again – 6,047 - https://familylocket.com/rlp-185-revisiting-timelines-and-analysis-again/ RLP 184: Revisiting Research Objectives Again – 5,872 - https://familylocket.com/rlp-184-revisiting-research-objectives-again/ RLP 186: Revisiting Locality Research Again – 5,820 - https://familylocket.com/rlp-186-revisiting-locality-research-again/ RLP 190: Revisiting Report Writing Again – 5,762 - https://familylocket.com/rlp-190-revisiting-report-writing-again/ RLP 156: Tracing 19th Century Germans with Heidi Mathis... – 5,692 - https://familylocket.com/rlp-156-tracing-19th-century-germans-part-1-the-nitty-gritty-of-german-names/ RLP 2: Research Objectives – 5,690 - https://familylocket.com/rlp-2-research-objectives/ RLP 1: Introduction – 5,665 - https://familylocket.com/rlp-1-introduction/ RLP 158: RLP with DNA Course with Allison Part 1 – 5,660 - https://familylocket.com/rlp-158-rlp-with-dna-ecourse-part-1/ RLP 100: Top Ten Tips to Research Like a Pro – 5,610 - https://familylocket.com/rlp-100-top-ten-tips-to-research-like-a-pro/ RLP 197: Proving Your Pedigree with DNA with Debra Hoffman – 5,606 - https://familylocket.com/rlp-197-proving-your-pedigree-with-dna-with-debra-hoffman/ Upcoming Conferences NGS GenTech Toolbox workshop by Nicole - Transcribing Handwritten Documents with Artificial Intelligence - https://www.ngsgenealogy.org/gentechtoolbox/transcribing-handwritten-documents-with-ai/ North Carolina Genealogical Society Virtual Conference March 27 – Using AI to Abstract 19th Century North Carolina Deeds by Nicole - https://www.ncgenealogy.org/event/2026-ncgs-virtual-conference/  National Genealogical Society Conference May 27-30 in Fort Wayne, Indiana - https://conference.ngsgenealogy.org/ - Nicole & Diana are giving several lectures on using AI to understand terminology, Barsheba Tharp DNA case, deciphering handwriting, court records, and finding females in court records. Sponsor – Newspapers.com For listeners of this podcast, Newspapers.com is offering new subscribers 20% off a Publisher Extra subscription so you can start exploring today. Just use the code "FamilyLocket" at checkout.  Research Like a Pro Resources Airtable Universe - Nicole's Airtable Templates - https://www.airtable.com/universe/creator/usrsBSDhwHyLNnP4O/nicole-dyer Airtable Research Logs Quick Reference - by Nicole Dyer - https://familylocket.com/product-tag/airtable/ Research Like a Pro: A Genealogist's Guide book by Diana Elder with Nicole Dyer on Amazon.com - https://amzn.to/2x0ku3d 14-Day Research Like a Pro Challenge Workbook - digital - https://familylocket.com/product/14-day-research-like-a-pro-challenge-workbook-digital-only/ and spiral bound - https://familylocket.com/product/14-day-research-like-a-pro-challenge-workbook-spiral-bound/ Research Like a Pro Webinar Series - monthly case study webinars including documentary evidence and many with DNA evidence - https://familylocket.com/product-category/webinars/ Research Like a Pro eCourse - independent study course -  https://familylocket.com/product/research-like-a-pro-e-course/ RLP Study Group - upcoming group and email notification list - https://familylocket.com/services/research-like-a-pro-study-group/ Research Like a Pro Institute Courses - https://familylocket.com/product-category/institute-course/ Research Like a Pro with DNA Resources Research Like a Pro with DNA: A Genealogist's Guide to Finding and Confirming Ancestors with DNA Evidence book by Diana Elder, Nicole Dyer, and Robin Wirthlin - https://amzn.to/3gn0hKx Research Like a Pro with DNA eCourse - independent study course -  https://familylocket.com/product/research-like-a-pro-with-dna-ecourse/ RLP with DNA Study Group - upcoming group and email notification list - https://familylocket.com/services/research-like-a-pro-with-dna-study-group/ Thank you Thanks for listening! We hope that you will share your thoughts about our podcast and help us out by doing the following: Write a review on iTunes or Apple Podcasts. If you leave a review, we will read it on the podcast and answer any questions that you bring up in your review. Thank you! Leave a comment in the comment or question in the comment section below. Share the episode on Twitter, Facebook, or Pinterest. Subscribe on iTunes or your favorite podcast app. Sign up for our newsletter to receive notifications of new episodes - https://familylocket.com/sign-up/ Check out this list of genealogy podcasts from Feedspot: Best Genealogy Podcasts - https://blog.feedspot.com/genealogy_podcasts/