Podcasts about Pregnenolone

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In this video, we're going to talk about progesterone in men. Progesterone is a precursor for testosterone and helps maintain healthy testosterone levels. Potential progesterone benefits for men include the following: •Anti-inflammatory •Decreases inflammation in the brain •Increases neurogenesis •Protects against dementia, Parkinson's, and Alzheimer's •Anti-depressant effects •Helps increase the production of sperm •Helps maintain muscle mass •Supports the immune system •Prevents the enlargement of the prostate •Helps reduce the risk of breast tissue in men Cholesterol is the raw material for all steroid hormones in the body. Statins block cholesterol and can inhibit your ability to make important hormones, leading to hormonal imbalance. Sardines, organ meats, fatty meat, and whole milk cheese are the best sources of cholesterol. Cholesterol is turned into pregnenolone, a “happy” hormone that helps increase other hormones. Pregnenolone is the precursor to progesterone. These 3 cofactors allow you to turn cholesterol into pregnenolone. 1. Magnesium Many people are deficient in magnesium. Increasing magnesium can often solve low testosterone. Avocados, leafy greens, pumpkin seeds, dark chocolate, or magnesium glycinate supplements are good sources of magnesium. 2. Zinc Zinc can increase testosterone levels. Shellfish, oysters, and red meat are the best sources of zinc. 3. Vitamin B3 Nutritional yeast supplements are the best source of niacin. Chronic stress, insulin, and endocrine disruptors can interfere with the biochemical pathways that support healthy hormone balance. Alcohol also decreases testosterone. Inflammation can negatively affect progesterone in men. Vitamin D can indirectly increase progesterone and testosterone by decreasing inflammation. You need at least 10,000 IU per day! If you have low progesterone or low testosterone, you'll need around 20,000 IU per day. If you want to boost testosterone, you need to consume quality protein. Grass-fed red meat is the best source. High-intensity interval training and resistance training stimulate the body to make more testosterone. Avoid overtraining!

When other factors are ruled out, many men with erectile changes are told “it must be “low-T.” As the market for male hormone replacement therapies grows, how do we better understand the important role testosterone plays in sexual health and well-being over the lifespan? Erica Leroye brings her quest to get a better grasp on the nitty gritty of testosterone and hormone health to Functional Medical Doctor and Men's Hormone Replacement Specialist Justin Smitherman ND,DC. Join these two as they discuss in easy to understand language: What Testosterone IS, what it does for the body and what part it plays in arousal sexuality, and stress management. Is there such a thing as "too much testosterone", "low T", and should we accept the "it's just natural decline, live with it" approach to ED? Recognizing signs and signals that point towards hormonal causes of erectile shifts The importance of self-advocacy when engaging with traditional medical care, key questions to ask when considering testing and replacement therapies, and lifestyle changes that can assist in hormonal well-being. For More Information and to Connect With Dr. Smitherman https://doctorsmitherman.com/ For More Information and to Connect With Erica Leroye https://www.flowcode.com/page/creativebodyrelease.com For More Information and to Connect With Soft Cock Appreciation Week https://www.softcockweek.com/ We have MERCH! Check out our storewww.softcockweek.com/store and support both Soft Cock Week and this year's, once we make a profit, partner SELFED (getselfed.org) Chapters 00:00 Introduction to Men's Health and Hormone Regulation 03:50 Understanding Testosterone and Its Importance 06:41 The Role of Testosterone in Aging 09:50 Identifying Low Testosterone Symptoms 12:39 The Connection Between Testosterone and Sexual Health 15:20 Exploring the Psychological Aspects of Low Libido 18:31 The Impact of Relationships on Testosterone Levels 21:17 Pregnenolone and Hormonal Balance 24:10 Conclusion and Key Takeaways 33:24 Understanding Individual Testosterone Levels 35:16 The Importance of Baseline Testing 39:53 Interpreting Testosterone Ranges 42:39 Diminishing Returns of Testosterone Levels 48:28 Exploring Testosterone Replacement Options 54:16 Navigating Telehealth and Consultations 58:31 Empowering Self-Advocacy in Healthcare 01:04:47 New Chapter men's health, testosterone, erectile dysfunction, aging, hormone therapy, sexual health, health advocacy, testosterone replacement therapy, low testosterone, soft cock week

In this episode of Hart2Heart with Dr. Mike Hart, Dr. Hart dives deep into advanced and practical health topics with Dr. Abud Bakri, a maternal medicine specialist based in California. Dr. Bakri discusses health optimization, the role of biohacking in modern medicine, and the split between traditional and wellness-focused primary care. They explore the effects of GLP-1 agonists like Ozempic, the benefits of DHT and testosterone, and practical strategies for hormone health and lifestyle improvement. Guest Bio and Links: Dr. Abud Bakri is a maternal medicine specialist based in California, known for his expertise in health optimization and wellness-focused medicine.  Listeners can learn more about Dr. Abud Bakri on YouTube, IG @abud_bakri, and X @AbudBakri Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart    (0:15) Dr. Hart introduces guest, Dr. Abud Bakri to the listeners (1:15) Dr. Abud Bakri's medical background (3:30) The evolution of medicine and health optimization (5:00) The role of GLP-1 agonists in weight management (8:00) Understanding obesity and brain reprogramming (12:15) Mechanisms and benefits of Ozempic (14:00) Challenges and strategies for long-term weight management (17:00) Leptin Resistance and its clinical implications (21:00) Testosterone vs. DHT - what men need to know (24:00) Causes of male pattern baldness (28:00) The role of DHT in cognitive and sexual function (33:00) Pregnenolone and Its importance in TRT (35:30) Testing and ratios: DHT and testosterone (38:00) The debate on HCG and LH stimulation (43:00) Natural supplements and estrogen blockers (45:30) Pheromones and their impact on attraction (53:00) Optimizing sleep for better health (56:00) Closing thoughts - taking charge of your health --- Dr. Mike Hart is a Cannabis Physician and Lifestyle Strategist. In April 2014, Dr. Hart became the first physician in London, Ontario to open a cannabis clinic. While Dr. Hart continues to treat patients at his clinic, his primary focus has shifted to correcting the medical cannabis educational gap that exists in the medical community.  Connect on social with Dr. Mike Hart: Social Links: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

What you know about melatonin & THC is WRONG. Dave Lee is the ultimate expert to men's health, testosterone, & sexual health - From issue resolution to optimization. Things you're taking that are reducing your masculinity, dht-blockers and finasteride, maximizing sexual health, botanicals on reducing libido, nandrolone and tren on pregnenolone and dhea, and everything we thought we knew about melatonin is wrong @imdaveleePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Watch The Podcast:https://www.youtube.com/channel/UCqgN2kieCEHwZ9M-QFBxfCgPharma TRT, GH analogs, peptides, IGF-1, var troche, fat-loss/hair-loss treatments, etc | HRT Men's Health Optimization: https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaHuge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00:00 - Teaser & Intro00:14:00 - Hormones & Sexual Health00:24:16 - Thoughts on HCG & Clomofine00:29:54 - Feminine symptoms00:40:52 - "Testosterone & TRT side effects00:51:38 - Effects of Cialis00:54:17 - Gear & Sexual Health00:58:10 -Finasteride01:02:22 - Bald & Beard01:05:43 - "Japanese Yakuza"01:06:00 - Melatonin01:12:43 - Cycling Melatonin01:16:11 - Optimizing Endogenous vs Exogenous Melatonin01:27:49 - Thoughts on KSM-66 & Ashwagandha01:35:24 - Lion's mane01:41:07 - Effects of Porn01:46:33 - Q & A01:50:37 - Testosterone cream01:55:46 - Pregnenolone deficiency & Sodium sensitivity#podcast #mentalhealth #holistic #health #hrt #story #discipline #fitness #ifbbpro #npc #bodybuilder #bodybuilding #workout #gym #nutrition #physique #classic

Are you thinking of taking a pregnenolone supplement? This hormone can be very helpful in improving adrenal fatigue and relieving symptoms of hormonal imbalances and other issues. However, before you take this supplement, here are some warnings and side effects that you should know about.Trying to find an integrative medicine or functional medicine doctor who understands what you're going through? Lam Clinic does Telemedicine all over the world and is only a phone call away.1. Educate yourself by visiting our website: www.lamclinic.com2. Call our office at 714-709-8000 to schedule an appointment.FIND US ONLINE HERE:» Website: https://www.lamclinic.com/» Facebook: https://www.facebook.com/lamclinic» Instagram: https://www.instagram.com/lam_clinic/» Tiktok: https://www.tiktok.com/@lamclinic» YouTube: https://www.youtube.com/LAMCLINIC

Sponsor: ⁠⁠⁠⁠⁠⁠London Nootropics⁠⁠⁠⁠⁠⁠: offrici un caffé nootropico, potenzia il cervello e comprendi meglio i nostri podcast! Per supportarci usa il codice "LIFEX" al momento dell'acquisto. Esiste davvero la stanchezza surrenale - e cosa cambierebbe se la chiamassimo ipocortisolismo funzionale? Scopriamo cosa succede nel nostro corpo quando ci stressiamo troppo e quando la situazione clinica delinea un quadro di stanchezza generica con sintomi vaghi e specifici. Vi siete mai sentiti così?

In this exclusive episode, I dove into the incredible world of pregnenolone, a crucial steroid hormone synthesized from cholesterol, vital for producing various sex hormones and balancing cortisol levels. I covered its profound impact on brain health, potentially guarding against neurodegenerative diseases like Alzheimer's, and its role in managing stress, hormone balance, and overall vitality. I also explored how pregnenolone can aid in managing conditions from menopause to autoimmune disorders, enhance skin health, and even support weight management. Discover Pregnenolone Fixxr: https://dramiehornaman.com/collections/supplements/products/pregnenolone-fixxr Shop ALL of Dr. Amie's Fixxr® Supplements: betterlifedoctor.com LET'S GET YOUR LIFE BACK...Connect with Dr. Amie Hornaman Book a free application call: https://dramiehornaman.com/pages/book-a-call FREE DOWNLOADS… What Are the Optimal Lab Ranges? What Steps Can I Take? Don't know where to start...don't know which labs are useful? And what to do when you get your results? “How To” Guide For Supplements Here's your Fixxr® supplement timeline and guide. Fix Your Thyroid and Adrenals To Fix Your Life Check your symptoms of hypothyroidism and know OPTIMAL thyroid lab values. Learn why you are being told you're “NORMAL” by your doctor. Can Supplements Help with Hypothyroidism? Grab this thorough guide to help you select the most advantageous supplements that will best suit your health circumstances. RATE, REVIEW AND FOLLOW ON APPLE PODCASTS Show your love for Amie and The Thyroid Fixer Podcast! If you're enjoying our journey together, I'd be thrilled if you could take a moment to rate and review the show on Apple Podcasts. Your support helps me reach and help more people just like you, guiding them towards their optimal selves! Just click HERE, scroll all the way down, give us those 5 stars, and share what you enjoy about my episodes in a review. Haven't subscribed yet? Make sure to follow The Thyroid Fixer Podcast to catch all the new episodes that come out every week. Follow HERE and never miss out on a moment of the journey! CONNECT WITH ME ON SOCIAL MEDIA: Join my exclusive Facebook Group, Dr. Amie…The Thyroid Fixer®...Love Your Mirror, for a Community of HOPE and Support in your thyroid journey. https://www.facebook.com/groups/dramie/ Like me on Facebook: Amie Hornaman Nutrition and Functional Medicine Subscribe on Youtube: Dr. Amie Hornaman Follow me on Instagram: @dramiehornaman

In this episode, we will talk about how chronically elevated cortisol can wreak havoc on our hormones, fertility, thyroid, and overall health and well-being, and natural, easy tips to reduce stress and cortisol.  Nutrition, sleep, herbal remedies, blood sugar management, sun and nature will all be explored as supportive tools for reducing stress and cortisol levels. TIMESTAMPS 01:10 what is stress? 03:00 What is cortisol? 04:10 Symptoms of high cortisol 05:00 Pregnenolone “steal” 08:50 How to reduce cortisol levels 15:50 Conclusion Use code “podcast” to save on your first of hormone-regulating herbs → https://www.peacelovehormones.com/collections/all/products/soothe  You may also like: - Why Nearly Everyone Should Use Ashwagandha → https://www.youtube.com/watch?v=76VEhSngbrU - Easy, natural sleep tips you NEED to transform your health! → https://podcasters.spotify.com/pod/show/peacelovehormonespodcast/episodes/Ep--60-Easy--natural-sleep-tips-you-NEED-to-transform-your-health-e21d9je

CistaMAX | The Road To The Perfect Cistanche This month on the In Search of Insight podcast, Emiel and Erika share the inspiration behind Nootropics Depot's new CistaMAX stack! We combined non-extracted Cistanche, a high-potency Cistanche extract, and a Supercritical Cistanche extract with Shilajit, Pregnenolone and DHEA to create CistaMAX. This combination produces a noticeable stimulating and motivating effect, and boosts the muscle-building properties of Cistanche. In this podcast, you'll learn why we chose each ingredient in CistaMAX and what purpose it serves in the stack as a whole. You'll also learn about the neuroscience behind the focus and mood enhancing effect of Cistanche. There's lots of reasons why we include CistaMAX in our daily stack - it can increase feelings of hunger, which is essential when bulking and building muscle. It also gives us a noticeable energy boost that makes us want to move more. CistaMAX is a great choice for supporting fitness, motivation, and hormonal balance. Listen to our new episode to learn more! Buy CistaMAX from Nootropics Depot https://nootropicsdepot.com/cistamax-capsules/ Follow Us on Social Media https://www.reddit.com/r/NootropicsDepot/ https://www.instagram.com/nootropicsdepot/ https://www.facebook.com/NootropicsDepot/ https://www.instagram.com/insearchofinsight?igsh=MTVtdDB1d2ZpZm9sbA%3D%3D&utm_source=qr Podcast Chapters 00:00 Introduction 00:32 Exploring the elements of CistaMAX 3:46 What is the best dose for CistaMAX? 7:53 Hunger-boosting effects of CistaMAX 15:52 Steroidogenesis - androgenic benefits of CistaMAX 20:24 Gut-health benefits of Cistanche 26:51 Echinacoside and Acetoside - active compounds 32:14 Perceptible benefits of CistaMAX 32:40 CistaMAX and glucose absorption 40:22 Developing the CistaMAX stack 51:03 Pregnenolone, DHEA, and Shilajit in CistaMAX 55:29 Motivation, energy, and mood boost 1:01:51 How to determine what is and isn't working in your stack 1:04:55 Does CistaMAX benefit workout recovery? 1:11:05 Conclusion

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Episode 278 | Understand what happens exactly when your brain interprets a stressor, how your body creates cortisol in response, what chronic stress is, how to support your cortisol and what the pregnenolone steal is.  erin@erinjoyceco.comFollow me on InstagramSubmit topic ideas and questions to erin@erinjoyceco.comBuy Motherhood Stripped!Check out freebies here. Find resources, information and connect with Erin through her website.

Stress is daunting, lurking in the shadows of our daily lives, from the innocent years on the playground to the relentless pressures of adulthood. Our latest conversation unpacks this challenge, laying out an arsenal of strategies to keep it at bay. We zero in on Pregnenolone, a supplement that may well be the best-kept secret for combating stress, as Christian recounts his encounters with this aid during sleep-deprived nights as a new father. The episode promises not just tales of struggle but also insights into how pregnenolone, along with allies like L-theanine and GABA, can bolster our mental fortitude, offering a beacon of hope for those seeking tranquility in turmoil.Christian Yordanov joins us, bringing his wealth of knowledge on the intricate dance between chronic stress and our pursuit of longevity. Drawing from his research on autism and wellness, Christian unveils the significance of confronting stress on a biochemical battlefield, extending beyond the usual eat-sleep-exercise mantra. Our discussion turns to his anticipation-worthy book, poised to reveal further secrets on fostering a life not just longer but richer in quality. Tune in for a thought-provoking exchange that will leave you equipped with practical mindfulness techniques, ready to transform your daily stressors into stepping stones toward a serene existence.For those who nurture others, the weight of caregiving can often be an unsung burden, one that can stealthily chip away at one's health. In this episode, we address this head-on, focusing on the necessity for caregivers to arm themselves against the silent threat of stress. Shattering the illusion that self-care is a luxury, we explore accessible lifelines such as calming teas and supplements, which can be the difference between thriving and merely surviving in these roles.  And remember to immerse yourself in our discussions beyond this episode by engaging with our vibrant social media community and subscribing to our YouTube channel for your regular dose of well-being wisdom.#StressManagement#Pregnenolone#MentalHealth#LTheanine#GABA#CaregiverWellness#SelfCare#WellBeingWisdom#Longevity#ChronicStress#CaregiverSupport#TranquilityInTurmoilLearn more about Christian at ChristianYordanov.com"Alzheimer's is heavy but we ain't gotta be!"IG: https://www.instagram.com/parentingupFB: https://www.facebook.com/parentingupYT:https://www.youtube.com/channel/UCDGFb1t2RC_m1yMnFJ2T4jwTEXT 'PODCAST" to +1 404 737 1449 - to give J topic ideas, feedback, say hi!

In this video, we're going to talk about preventing muscle loss due to aging. At around age 50, women go through menopause which causes hormonal changes. Men experience hormonal changes around age 60. As you age and your hormones change, you can become deficient in skeletal muscle. This is known as sarcopenia. Around 40% of your metabolism is related to your muscles, so this can have detrimental effects. In women, estrogen decreases with age, but progesterone drops even lower. Without progesterone, you end up with a lot of problems from estrogen. Cholesterol is a building block for steroid hormones, like testosterone and estrogen, which directly affect your muscles. This is why low-cholesterol and low-fat diets can cause muscle loss. Coincidentally, this is why you see muscle damage and diseases associated with statin drugs. Here are 6 ways to protect and support your hormones to help prevent muscle loss as you age: 1. Infrared light can increase melatonin. Sunlight, fire, and candles all provide infrared light. 2. Regular, consistent, resistance exercise is the most potent stimulator of muscle building. 3. Ensure adequate intake of high-quality animal protein. Aim for .8 to 1.2 grams of protein per kilogram of body weight each day. 4. Consume plenty of cholesterol from meat and dairy. 5. Try pregnenolone supplements. Start out with 30 mg per day for women and 100 mg for men. Pregnenolone is a precursor for important hormones related to muscle building. 6. DHEA is a precursor for hormones that help build muscle. Try 25 mg for women and 100 mg for men. DATA: https://pubmed.ncbi.nlm.nih.gov/6122168/ https://www.frontiersin.org/articles/...

Dive into the fascinating world of hormonal balance in this enlightening episode of "Stop Aging Now," where Dr. Nick Delgado shines a spotlight on "Understanding the Influence of Pregnenolone over Natural Hormones." As the precursor to all steroid hormones, pregnenolone plays a pivotal role in maintaining hormonal harmony within the body. Dr. Delgado explores the science behind this powerful neurosteroid, its impact on our health, and how it can be optimized to support overall well-being. Listeners will gain a deeper understanding of how pregnenolone works in synergy with the body's natural hormones to regulate mood, energy, brain function, and more. Dr. Delgado discusses the conditions that can arise from pregnenolone imbalances and provides insights into natural ways to enhance its production, including dietary changes, lifestyle modifications, and targeted supplementation. This episode is an essential listen for anyone looking to navigate the complexities of hormonal health, seeking natural strategies for anti-aging, or simply curious about the body's intricate biochemical pathways. Join Dr. Nick Delgado on "Stop Aging Now" for a journey into the heart of hormonal health and discover how to harness the power of pregnenolone for a vibrant, balanced life. If you find yourself captivated and yearning for a deeper dive into your personal health journey, I'd be honored to guide you. Join me in my exclusive 'Health Coaching and Guidance Program'. Together, let's design a roadmap tailored to your unique needs and aspirations. Reach out, and together, we'll navigate the path to optimal health and understanding Check out my new book, “STOP AGING NOW”: https://stopagingnowbook.com/ https://www.amazon.com/Stop-Aging-Now-Seven-Secrets/dp/B0CGKTX7HG For More Info... • Apply for a coaching program: https://nickdelgado.com/ • Subscribe to our YouTube channel:  https://www.youtube.com/delgadovideo • Shop here for our amazing supplements: https://estroblock.com/
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In this podcast, we're going to talk about preventing muscle loss due to aging. At around age 50, women go through menopause which causes hormonal changes. Men experience hormonal changes around age 60. As you age and your hormones change, you can become deficient in skeletal muscle. This is known as sarcopenia. Around 40% of your metabolism is related to your muscles, so this can have detrimental effects. In women, estrogen decreases with age, but progesterone drops even lower. Without progesterone, you end up with a lot of problems from estrogen. Cholesterol is a building block for steroid hormones, like testosterone and estrogen, which directly affect your muscles. This is why low-cholesterol and low-fat diets can cause muscle loss. Coincidentally, this is why you see muscle damage and diseases associated with statin drugs. Here are 6 ways to protect and support your hormones to help prevent muscle loss as you age: 1. Infrared light can increase melatonin. Sunlight, fire, and candles all provide infrared light. 2. Regular, consistent, resistance exercise is the most potent stimulator of muscle building. 3. Ensure adequate intake of high-quality animal protein. Aim for .8 to 1.2 grams of protein per kilogram of body weight each day. 4. Consume plenty of cholesterol from meat and dairy. 5. Try pregnenolone supplements. Start out with 30 mg per day for women and 100 mg for men. Pregnenolone is a precursor for important hormones related to muscle building. 6. DHEA is a precursor for hormones that help build muscle. Try 25 mg for women and 100 mg for men. DATA: https://pubmed.ncbi.nlm.nih.gov/6122168/ https://www.frontiersin.org/articles/...

Welcome to the podcast with Dr. Brendan McCarthy! Today, cholesterol-lowering drugs are the most commonly prescribed medications in the United States. These drugs induce side effects and fail to address the underlying reason (hormone deficiency) for why the body is overproducing cholesterol. This Episode talks about what Pregnenolone may do for Cholesterol Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he's been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 --More Links-- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com

For more information about how I can help you visit my site BetterByDrBrooke.com. When it comes to taking hormones, attention often goes to estrogen, progesterone and testosterone but there are two other hormones to consider: dhea and pregnenolone. These are usually thought of as “precursor hormones” that can be taken and then turned into estrogen and testosterone - and they can be. However, they both have actions and benefits of their own specifically with regards to comes to memory, mood and energy/stamina so they may have a place in your regimen. They do though convert to other hormones so testing is important and side effects can certainly arise.    To work with Dr Brooke click here and if you loved this episode please leave a review!     Follow Dr Brooke on Instagram and get signed up for my awesome emails here. Seriously,I write really great emails, or so 1000s of women tell me and I'd like to send you one too.   Be sure you connect with me in my FREE PRIVATE Facebook group: Hormones & Happiness with Dr Brooke where other amazing, like minded women like YOU are already hanging out! Join us!   Partners of the Dr. Brooke Show (Stuff I Know You Will Love!)   Using a natural, fluoride free toothpaste? It may still have a variety of preservatives and harsh ingredients that can damage your teeth enamel like charcoal and baking soda. But no worries cuz NOBS toothpaste tablets may just solve all your natural dental care problems!    With nano hydorxyapatite and super gentle polishing ingredients you'll actually be remineralizing your teeth making them not only more beautiful but stronger and healthier. PLUS they come in a glass jar instead of a plastic tube and there's no sticky mess like with toothpaste because they are tablets you chew before you brush making them also great for kids and travel! I'm kinda in love. Save 15% off this toothpaste with no BS with this link!   This episode is also sponsored by LMNT Electrolytes! These high sodium, well balanced hydration boosters are perfect for low carb dieters, those doing keto or when employing intermittent or any type of fasting. Skip the brain fog, low energy, cravings and perform better with LMNT electrolytes. Get your FREE sample pack here! 

Oxytocin is often referred to as the "love hormone" or the "cuddle hormone" due to its association with feelings of love, bonding, and intimacy. However, it is much more than that. Oxytocin is a master hormone that plays a crucial role in various physiological functions and has a significant impact on our overall well-being. In this episode, I had the pleasure of sitting down with the amazing Dr. Sahar Swidan to discuss the power of Oxytocin and its impact on our overall well-being. Dr. Sahar, President and CEO of NeuroPharm, and an internationally renowned speaker and expert in pain management, headaches, and HRT, shares her insights and expertise on this fascinating topic. We delve into the role of Oxytocin in combating stress, promoting positive emotions, and fostering stronger connections with others. It truly is a hormone that can transform our lives!  Dr. Sahar also shares her expertise on how to harness the benefits of Oxytocin in our daily lives, including practical tips on microdosing Oxytocin throughout the day. We also touch on the importance of healthy eating, protein shakes, and maintaining hormonal balance for optimal health. As your trusted Girlfriend Doctor, I am committed to helping you navigate all stages of life with confidence and vitality. Whether you're looking to reduce stress, enhance your relationships, or simply boost your mood, this episode has something for everyone!   Key Takeaways: [00:04:49] Oxytocin is a master hormone.  [00:06:24] Oxytocin deficiency in society. [00:08:07] Master switch hormone and its function in the brain. [00:12:30] Delivery methods for Oxytocin. [00:17:06] Injecting Pitocin for Oxytocin. [00:19:01] The power of hugs and kisses. [00:24:20] Neuroprotective effects of pregnenolone. [00:27:20] Heart disease in women. [00:30:03] Progesterone and clotting disorders. [00:35:17] Dr. Sahar's new book. [00:38:23] Medications and cleaner alternatives. [00:43:19] Using DHEA as a preventative. [00:45:07] Urinary incontinence and hormone replacement. [00:47:52] Microdose Oxytocin throughout the day. Memorable Quotes:   "I think we all really are Oxytocin deficient nowadays, because a lot of us have lost two to three years, depending on the lockdowns and what state you were in, because we really miss being with our loved ones and family and friends and girlfriends, which I always say is the best form therapy." [00:06:24] – Dr. Sahar Swidan   "The studies have shown that you gotta hug somebody at least 20 seconds, minimally, to increase the release of oxytocin. So, these quick hugs that we all do because everybody's so rushed, it doesn't release Oxytocin. So, make sure all of your hugs to your kids, spouses, friends, girlfriends, humanity, whatever, whoever needs a hug, it's 20 seconds or more. " [00:18:56] – Dr. Sahar Swidan Connect with Dr. Sahar Swidan: Skincare Website Website LinkedIn Facebook Instagram   Connect with Dr. Anna Cabeca: Website Instagram  

Oxytocin is often referred to as the "love hormone" or the "cuddle hormone" due to its association with feelings of love, bonding, and intimacy. However, it is much more than that. Oxytocin is a master hormone that plays a crucial role in various physiological functions and has a significant impact on our overall well-being. In this episode, I had the pleasure of sitting down with the amazing Dr. Sahar Swidan to discuss the power of Oxytocin and its impact on our overall well-being. Dr. Sahar, President and CEO of NeuroPharm, and an internationally renowned speaker and expert in pain management, headaches, and HRT, shares her insights and expertise on this fascinating topic. We delve into the role of Oxytocin in combating stress, promoting positive emotions, and fostering stronger connections with others. It truly is a hormone that can transform our lives!  Dr. Sahar also shares her expertise on how to harness the benefits of Oxytocin in our daily lives, including practical tips on microdosing Oxytocin throughout the day. We also touch on the importance of healthy eating, protein shakes, and maintaining hormonal balance for optimal health. As your trusted Girlfriend Doctor, I am committed to helping you navigate all stages of life with confidence and vitality. Whether you're looking to reduce stress, enhance your relationships, or simply boost your mood, this episode has something for everyone!   Key Takeaways: [00:04:49] Oxytocin is a master hormone.  [00:06:24] Oxytocin deficiency in society. [00:08:07] Master switch hormone and its function in the brain. [00:12:30] Delivery methods for Oxytocin. [00:17:06] Injecting Pitocin for Oxytocin. [00:19:01] The power of hugs and kisses. [00:24:20] Neuroprotective effects of pregnenolone. [00:27:20] Heart disease in women. [00:30:03] Progesterone and clotting disorders. [00:35:17] Dr. Sahar's new book. [00:38:23] Medications and cleaner alternatives. [00:43:19] Using DHEA as a preventative. [00:45:07] Urinary incontinence and hormone replacement. [00:47:52] Microdose Oxytocin throughout the day. Memorable Quotes:   "I think we all really are Oxytocin deficient nowadays, because a lot of us have lost two to three years, depending on the lockdowns and what state you were in, because we really miss being with our loved ones and family and friends and girlfriends, which I always say is the best form therapy." [00:06:24] – Dr. Sahar Swidan   "The studies have shown that you gotta hug somebody at least 20 seconds, minimally, to increase the release of oxytocin. So, these quick hugs that we all do because everybody's so rushed, it doesn't release Oxytocin. So, make sure all of your hugs to your kids, spouses, friends, girlfriends, humanity, whatever, whoever needs a hug, it's 20 seconds or more. " [00:18:56] – Dr. Sahar Swidan Connect with Dr. Sahar Swidan: Skincare Website Website LinkedIn Facebook Instagram   Connect with Dr. Anna Cabeca: Website Instagram  

This week, we're replaying our most popular episode of all time. Season One's "What's the Deal with the Pregnenolone Steal?" dives into the controversy around Adrenal Fatigue. Hear from Tom Guilliams, PhD, an expert in cortisol and the HPA axis, about how the brain is responsible for signaling the cortisol response, and why the adrenal glands don't just “steal” pregnenolone to make cortisol. Show Notes Books to learn more about the HPA axis: The Role of Stress and the HPA axis in Chronic Disease Management (Guilliams) Integrative Medicine (Rakel) Why Zebras Don't Get Ulcers (Sapolsky) Visit Tom Guilliams' website https://www.pointinstitute.org/ Become a DUTCH provider and profoundly change your patients' lives through comprehensive hormone testing. Read the DUTCH Blog to learn more about hormone health. Assessing Chronic Fatigue with the Cortisol Awakening Response Circadian Rhythm and Human Health You Need Free Cortisone and Metabolized Cortisol to Evaluate HPA Axis Health 

Dr. Natalie Underberg, a functional medicine doctor and PCOS specialist, discusses the importance of a healthy environment for pregnancy and reducing stress. She highlights the impact of cortisol and sympathetic states on fertility and suggests steps to reduce stress and establish healthier boundaries. Dr. Underberg also emphasizes the importance of being mindful of toxin exposure and hormonal balance before conception. 01:43 PCOS and improving fertility.04:26 Fertility and infertility trends.06:12 Birth control and infertility.12:06 Emotional trauma and hormonal health.14:44 Natural light and sleep rhythm.17:03 Cortisol and infertility correlation.19:37 Three Gates and Organ Health.24:09 Relinquishing control and finding balance.26:14 Body readiness for pregnancy.29:43 Lack of control in fertility.33:20 Small changes for fertility.37:00 Pregnenolone and DHEA success.41:05 Preconception care and preparation.43:11 Importance of physical readiness.46:31 Fertility and male health.50:18 Pesticides and fertility outcomes.52:24 Improving male fertility.56:45 The Pregnancy Prep Academy.58:45 A beautiful lady sandwich.Order, track, and get results from 30+ lab companies with Rupa Health—FREE for practitioners! Sign up or schedule a demo at RUPAHEALTH.COMFor a limited time, join Levels and receive an additional 2 FREE months on your annual membership! Unlock your offer at:LEVELS.LINK/ANCIENTHEALTH PCOS Collective Work with Dr. Natalie Underberg Shop Dr. Natalie Underberg's supplements Check out Dr. Natalie Underberg's Pregnancy Prep AcademyFollow Dr. Natalie on Instagram: @the.pcos.docFollow our Hosts on Instagram: @organic_blondie, and @doctormotley Follow @healthinstitute on Instagram! Join The Health Institute Newsletter!

Testo-Launch course - everything you need to know about testosterone optimization

Haylie Pomroy discusses the science behind the Fast Metabolism Diet, the benefits of being able to metabolize cholesterol efficiently, and the master hormone we need to access for better metabolism. Pregnenolone is the precursor to all the metabolic processes working and is capable of being converted into sex hormones and natural steroids our body needs. The Fast Metabolism Diet is strategically designed to access and produce these healthy subst   Key Points: 00:00 Introduction 01:18 The master hormone we need to access 03:13 How pregnenolone is converted for use 04:18 What are glucocorticoids? 05:48 What are mineralocorticoids? 07:30 The importance of vitamin D 08:24 Do this if you have low vitamin D 09:33 Advice for those without a gallbladder 10:25 Why do the Fast Metabolism Diet? ] Got questions? Join our community FREE for 30 Days!

Haylie Pomroy discusses the science behind the Fast Metabolism Diet, the benefits of being able to metabolize cholesterol efficiently, and the master hormone we need to access for better metabolism. Pregnenolone is the precursor to all the metabolic processes working and is capable of being converted into sex hormones and natural steroids our body needs. The Fast Metabolism Diet is strategically designed to access and produce these healthy subst   Key Points: 00:00 Introduction 01:18 The master hormone we need to access 03:13 How pregnenolone is converted for use 04:18 What are glucocorticoids? 05:48 What are mineralocorticoids? 07:30 The importance of vitamin D 08:24 Do this if you have low vitamin D 09:33 Advice for those without a gallbladder 10:25 Why do the Fast Metabolism Diet? ] Got questions? Join our community FREE for 30 Days!

Do you want to feel like your best self again? Are you tired of feeling sluggish and unmotivated? The solution to achieving optimal health and vitality lies in addressing the root causes of low testosterone. And that's exactly what our guest, Dr. Tracy Gapin, will be sharing with you. Dr. Gapin has a wealth of experience as a board-certified urologist and a renowned expert in men's health, Dr. Gapin has made it his mission to help men achieve hormonal balance and overall wellness. As the founder of the esteemed Gapin Institute, he's become well-known for his focus on addressing the root causes of low testosterone through detox, nutrition, and hormonal management. His extensive work has been instrumental in helping men enhance their health, energy, and vitality. By detoxing your body, providing the right nutrition, and managing your hormones, you can experience improved energy levels, increased muscle mass, improved sexual function, and an overall improved quality of life. Don't settle for feeling less than your best.  Join us as we uncover the secrets to optimizing your testosterone levels and achieving the health and vitality you deserve. KEY TAKEAWAYS [2:11] Overdosing Testosterone in Men [6:08] The Testosterone Epidemic [9:16]  Endocrine Disruptors [12:28] The Approach to Low Testosterone [14:00] Understanding Testosterone Levels [15:24] Testosterone Therapy [17:10]- Benefits of Testosterone [20:03] Stopping Testosterone Therapy [24:10] Comprehensive Approach to Hormone Health [26:23] The Impact of Testosterone Optimization on Relationships [31:43] The Importance of Free Testosterone [34:30] Testosterone Therapy and Prostate Cancer [36:07] The Importance of Proper Screening for Men's Health [28:05] The Sexual CPR Program 00:38:54 - Importance of DHEA for Balancing Cortisol 00:39:51 - Progesterone and Pregnenolone for Sleep and Adrenal Support 00:40:51 - Nitric Oxide for Sexual and Vascular Health 00:44:10 - Elevated Red Blood Cells and Testosterone Use 00:45:36 - Natural Solutions for Optimizing Testosterone Levels   MENTIONED IN THIS EPISODE Gapin Institute Website: https://gapininstitute.com/ Dr. Gapin Website: https://drtracygapin.com/# Instagram: https://www.instagram.com/drtracygapin/ Free Digital Copy of Dr. Gapin's book: Text “Health” to 26786 to receive 10 Secrets to High Performance Health   MEMORABLE QUOTES “I believe the success you achieve in every area of your life starts and ends with your health. And for men, there's a lot of things that that includes, but the first one is testosterone.” Dr. Tracy Gapin “When we take a man who is low and get into the optimal levels, you see a light switch turn on, you see an incredible difference in the way that guy shows up in life.” Dr. Tracy Gapin “If we're able to reduce cardiovascular risk, improve muscle mass, burn visceral fat, improve insulin sensitivity, improve your sleep and cognitive function, and help with your sex drive and function, why on earth would you want to stop testosterone therapy?” Dr. Tracy Gapin RESOURCES MENTIONED: Mighty Maca Plus   To learn more about me, and to stay connected, visit the links below: Website: The Girlfriend Doctor Instagram: The Girlfriend Doctor  

Do you want to feel like your best self again? Are you tired of feeling sluggish and unmotivated? The solution to achieving optimal health and vitality lies in addressing the root causes of low testosterone. And that's exactly what our guest, Dr. Tracy Gapin, will be sharing with you. Dr. Gapin has a wealth of experience as a board-certified urologist and a renowned expert in men's health, Dr. Gapin has made it his mission to help men achieve hormonal balance and overall wellness. As the founder of the esteemed Gapin Institute, he's become well-known for his focus on addressing the root causes of low testosterone through detox, nutrition, and hormonal management. His extensive work has been instrumental in helping men enhance their health, energy, and vitality. By detoxing your body, providing the right nutrition, and managing your hormones, you can experience improved energy levels, increased muscle mass, improved sexual function, and an overall improved quality of life. Don't settle for feeling less than your best.  Join us as we uncover the secrets to optimizing your testosterone levels and achieving the health and vitality you deserve. KEY TAKEAWAYS [2:11] Overdosing Testosterone in Men [6:08] The Testosterone Epidemic [9:16]  Endocrine Disruptors [12:28] The Approach to Low Testosterone [14:00] Understanding Testosterone Levels [15:24] Testosterone Therapy [17:10]- Benefits of Testosterone [20:03] Stopping Testosterone Therapy [24:10] Comprehensive Approach to Hormone Health [26:23] The Impact of Testosterone Optimization on Relationships [31:43] The Importance of Free Testosterone [34:30] Testosterone Therapy and Prostate Cancer [36:07] The Importance of Proper Screening for Men's Health [28:05] The Sexual CPR Program 00:38:54 - Importance of DHEA for Balancing Cortisol 00:39:51 - Progesterone and Pregnenolone for Sleep and Adrenal Support 00:40:51 - Nitric Oxide for Sexual and Vascular Health 00:44:10 - Elevated Red Blood Cells and Testosterone Use 00:45:36 - Natural Solutions for Optimizing Testosterone Levels   MENTIONED IN THIS EPISODE Gapin Institute Website: https://gapininstitute.com/ Dr. Gapin Website: https://drtracygapin.com/# Instagram: https://www.instagram.com/drtracygapin/ Free Digital Copy of Dr. Gapin's book: Text “Health” to 26786 to receive 10 Secrets to High Performance Health   MEMORABLE QUOTES “I believe the success you achieve in every area of your life starts and ends with your health. And for men, there's a lot of things that that includes, but the first one is testosterone.” Dr. Tracy Gapin “When we take a man who is low and get into the optimal levels, you see a light switch turn on, you see an incredible difference in the way that guy shows up in life.” Dr. Tracy Gapin “If we're able to reduce cardiovascular risk, improve muscle mass, burn visceral fat, improve insulin sensitivity, improve your sleep and cognitive function, and help with your sex drive and function, why on earth would you want to stop testosterone therapy?” Dr. Tracy Gapin RESOURCES MENTIONED: Mighty Maca Plus   To learn more about me, and to stay connected, visit the links below: Website: The Girlfriend Doctor Instagram: The Girlfriend Doctor  

Carrie Bennett joins me to discuss the effect of our light environment on hormones and fertility, why drinking coffee then fasting till midday is a bad idea, how WiFi and other sources of non-native EMF are harming you, why should see the morning sunrise.Carrie Bennett is a quantum health practitioner and educator. She is the lead faculty member and on the Board of Advisors for the Quantum Biology Collective, the world's premier certification for Applied Quantum Biology in clinical practice.TIMESTAMPS00:00:48 Carrie's approach to optimising health 00:03:35 Light environment vs other lifestyle causes of subfertiliy00:05:20 Daily routines and harms non-native EMF exposures 00:08:47 What is the role of the hormone leptin?00:11:50 Dr Max's analogy for leptin resistance00:12:45 The effect of light on leptin and other hormones00:14:52 Importance of breakfast and AM light for fertility00:18:54 Effect of intermittent fasting & AM routine on cortisol, insulin, leptin & weight loss00:23:05 Disrupting melatonin with artificial light & cortisol00:26:58 Pregnenolone steal syndrome00:29:50 The biological harm of non-native electromagnetic fields (EMFs)00:34:49 Carrie's practical approach to optimizing hormones00:39:30 Closing thoughts FURTHER READINGMartin Pall non-native EMF: https://pubmed.ncbi.nlm.nih.gov/?term=Pall+ML&cauthor_id=25879308Follow CARRIEInstagram: https://www.instagram.com/carriebwellness/Youtube: https://www.youtube.com/@carriebwellnessCarrie's website: https://www.carriebwellness.com/Carrie's online courses: https://www.carriebwellness.com/store Quantum Biology Certification Course for Practitioners - https://www.circadiancertified.com/courses/quantum-biology-level-1-circadian-certifiedFollow DR MAXTwitter: https://twitter.com/MaxGulhaneMDInstagram: https://twitter.com/MaxGulhaneMDApple Podcasts:  https://podcasts.apple.com/podcast/id1661751206Spotify:  https://open.spotify.com/show/6edRmG3IFafTYnwQiJjhwRLinktree: https://linktr.ee/maxgulhanemd#light #mitochondria #mitochondriac #circadianhealth #sun #sunlight #circadianrhythm #water #mitochondrialdisease

In todays episode I talk through what the Pregnenolone Steal is and how it's impacting your energy, fat loss efforts and hormones.Three things I discuss:What is Pregnenolone and why is it importantHow our bodies response to the outside world impacts hormonal statusHow to shift your lifestyle to increase your vital hormones► 4 Ways I Can HelpWork With Us Directly: https://bodyreset.online/work-with-us/Top Giveaways: https://bodyreset.online/top-giveaways/Free Facebook Group: https://www.facebook.com/groups/624778944323289YouTube: https://www.youtube.com/c/OllyWoodMPInstagram: https://www.instagram.com/ollywoodnz/

In this week's episode of ReInvent Healthcare, we talk about the interactions between sex hormones and adrenal glands, what tests can be done and how to assess for dysfunctions so that we, as practitioners can recommend the best course of action that our clients can take in order to help them get well.    IN THIS EPISODE: Cholesterol and Pregnenolone Steal Not very many people are aware or remember that Cholesterol helps create the sex hormones. Cholesterol needs Vitamin B5 in order to get to the next step which is Pregnenolone. So what exactly is Pregnenolone Steal? Learn more in this episode. Sex Hormone Imbalance and Adrenal Dysfunction Sex Hormone Imbalance is very much related to Adrenal Dysfunction. That is why when you approach a client with a Sex Hormone Imbalance, you need to assess cortisol levels and get their stress and adrenal function under control. The Importance of Cortisol Cortisol plays an important role in stress response. If one is under a lot of stress, pregnenolone is going to be converted to cortisol, and lead to imbalances in sex hormones.  So it is  important to get stress under control in order to control libido and menstrual cycles.    RESOURCES: Get our FREE Guide to Taking a Detailed Health History that gets you to root causes with ease.  Read through our FREE Adrenal Guide. Access Additional Resources for Practitioners ready to improve clinical outcomes through our Nutritional Endocrinology Practitioner Training.   Watch our recorded Thyroid Adrenal Workshop here. Check out the Hormone Interaction image I mentioned during the episode here.

Could a functional hormone panel explain your fatigue and resistance to weight loss? The answer is yes, but it's really difficult to find a solution to hormonal imbalances through conventional testing. Here's why: Hormonal imbalances can cause a multitude of symptoms such as weight loss resistance, fatigue, anxiety, depression, and common menstrual cycle symptoms like mood swings, breast tenderness and PMS. Evaluating hormones through conventional hormone labs are equivocally comparable to looking at a small part of a bigger picture. So, what's the preferred approach for hormone health and what are the reasons why you should get a functional hormone panel? Stay tuned as I unravel the mystery of hormone testing and why the basic conventional markers such as TSH, T4, estradiol, etc., will not give you the whole picture. In this episode, I discuss my top three reasons for a functional hormone panel: The concept of ‘pregnenolone steal' and how chronic stress creates an environment that to make an insufficient amount of sex hormones. Not only looking at sex hormones like estrogen and testosterone, but also testing for an imbalance in the adrenal hormones. This can lead to an irregular cortisol pattern, blood sugar imbalances, anxiety, weight gain, and excessive hunger.  Understanding your risks for breast cancer by evaluating estrogen metabolites. Functional hormone panels are great for looking at the individual pathways of estrogen molecules and whether the estrogen in your body is more prone to being protective or promoting of breast cancer. Let's get into it!  Interested in our Lean for Life Membership? Help yourself feel aligned using our three phase approach: Lean for Life Membership called Heal, Optimize , and Refine where you will be empowered to reverse previous metabolic damage with the assistance of our team of Registered Dietitian Nutritionists. Check out more details on our website! Want to learn more about our one-on-one Empowered Nutrition coaching? Book a free chemistry call to discuss your story and see if we're a good fit. Enjoying the podcast? Please review the Empowered Nutrition Podcast on Apple Podcasts or wherever you listen! Then, send me a screenshot of your positive review to podcast@empowerednutrition.health as a DM on Instagram (empowerednutrition.health). Include a brief description of what you're working on with your health and/or nutrition and I'll send you a free custom meal plan! Do you have questions you would like answered on the Empowered Nutrition podcast? You can propose your questions/ideas here or reach out to me at podcast@empowerednutrition.health

Pregnenolone | The Master Hormone Precursor | A Perfect Ally For Testosterone Boosting SupplementsIn Search Of Insight Episode #016 - PregnenoloneSupplementing Pregnenolone in low doses can help us balance our hormonal profiles, build muscles, and maintain a positive mood. Gain a deeper understanding of our body's hormone production process, and how Pregnenolone works as the master hormonal precursor. This month, your hosts Emiel and Erika dive into an exciting conversation and discuss:Pregnenolone, the master precursor to our body's steroid hormonesHow pregnenolone transforms into testosterone, estrogen, and corticosteroidsWhy less is more when dosing Pregnenolone for daily supplementationPregnenolone stack combinations to optimize hormonal balanceNew products from Nootropics DepotBuy Nootropics Depot Pregnenolone Tabletshttps://nootropicsdepot.com/pregnenolone-quick-dissolve-tablets/Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.Follow Us On Social Mediahttps://www.facebook.com/NootropicsDepot/https://www.instagram.com/nootropicsdepot/https://www.reddit.com/r/NootropicsDepot/new/

Low carb? Keto? Low fat? Fasting? In this episode, Katie Wells and Joe talk about her experience with dieting, some of the benefits she gets from intermittent fasting, and they discuss the controversial topic of cholesterol (spoiler: lower is not necessarily better). Katie shares some of her favorite health hacks, and they talk about how genetics can influence a person's health and how to use this information to live optimally. They also discuss which and how to track labs, the importance of optimal vs normal ranges, and what Katie does to hack her sleep & mood. Katie Wells is the founder and CEO of wellnessmama.com and wellnesse.com. A mom of 6, she took her health into her own hands and started researching to find the answers to her health struggles. She has written over 1,500 blog posts, 3 books, and was named one of the most influential people in health and wellness. This interview is not intended as medical advice. - Check out SelfDecode - Join Joe's online community - Follow Joe on Instagram Timestamps: (0:00) - Introduction (1:04) - How Katie got into health (3:53) - The Personalized Health Podcast? (4:57) - Shifting of health goals (6:44) - Katie's current health goals (8:14) - Joe shares his health journey (9:04) - What labs to track for anti-aging? (10:32) - Alcohol and saturated fats affect on health (12:31) - Katie Wells thoughts on LDL cholesterol (13:24) - Over-dieting and under nourishing (16:52) - Unsullied by paid sponsors (17:18) - Megadosing and metabolic flexibility (18:45) - Katies daily supplement intake & fasting (20:01) - The mental and spiritual benefits of a long fast (22:15) - Joe's experience with fasting (23:42) - What supplements does Katie take now? (24:39) - Pregnenolone dosages & benefits (25:40) - Nootropic stack for focus (26:37) - Tips to improve sleep from Katie (28:45) - Katie's most successful health “experiments” (30:09) - The importance of protein in your diet (31:40) - The last time Katie changed her mind about a health topic (32:42) - The best health hack Katie wished she found earlier (34:52) - Katie's top hacks to optimize mood (36:36) - The difference between normal and optimal lab ranges (37:45) - How using SelfDecode can help optimize your lab levels (38:58) - The most interesting DNA discovery (41:10) - Katie's expectations on her life span (43:15) - Characteristics that make you successful

I recently joined Christa Biegler RD on The Less-Stressed Life Podcast to talk about all things stress, hormones, and how to mitigate hormonal issues due to stress. Topics include:   - Top Causes of Low Hormones - Hormone That Drop Under Stress - Why Hormones Become Depleted During Stress - Debunking the Pregnenolone Steal Myth - Debunking Cholesterol Fears - Hormone Testing Recommendations - Where to Start if You Feel Fatigued ----------  My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization  www.metabolismschool.com ----------  No-Cost Coaching Resources for Our Listeners The Check-In Checklist: www.Sammillerscience.com/checklist  The Metabolism School Mini Series: www.sammillerscience.com/metabolism ----------  Stay Connected Instagram: @sammillerscience Facebook: The Nutrition Coaching Collaborative Community  https://www.facebook.com/groups/nutritioncoachingcollaborative TikTok: @sammillerscience - https://vm.tiktok.com/ZTdPVQtMH/ ---------- “This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at team@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast.”

Hormones are chemical messengers for thousands of biological processes in the body. Throughout your life, these messengers play an important role in muscle and skin tone, bone health, sleep, and energy levels. Hormone imbalance can occur at any age and contribute to diseases such as osteoporosis, dementia, cancer, and heart disease. Although hormonal changes can cause significant issues, these can be treated. My patients and coaching clients are often surprised at how easy it is to improve their symptoms and how great they feel once their hormones are back in balance. If you are a man struggling with low energy, low libido, trouble sleeping or pesky weight gain – this episode is for you. And ladies, this matters for you too because research has shown that fluctuating levels of estradiol, progesterone, testosterone and cortisol can often be the root cause of many health conditions such as:Menstrual cycle irregularitiesMood swingsSleep pattern disturbancesAppetite disordersLow Sex driveAnd if left untreated chronic hormonal imbalances can cause:PMSAnovulationInfertilityAmenorrheaEndometriosisPolycystic Ovary DiseaseOsteoporosis TODAY'S SHOW NOTES:1. What are the male hormones?  Men's sexual hormones are collectively called the androgens and include: testosterone, androstenedione (andro), andros-             tenediol, di-hydro-testosterone (DHT),dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) a                   more complex form of DHEA. 2. How are the male hormones made?  All hormones are built from cholesterol and are converted into pregnenolone and 17a-hydroxypregnenolone. Pregnenolone is       the primary steroid hormone that is broken down or metabolized into all the other steroid hormones for both men and                         women. Sometimes we call pregnenolone the 'mother hormone' and cholesterol the 'grandmother.' More questions covered in this episode:3. Where are the male hormones made?4. What are the main methods for measuring male hormones? 5. All  7 'Secrets' For Keeping Male Hormones In Balance including: important functional medicine testing, critical test biomarkers, androgenic foods, key supplements for male hormone health, stress theory and practices for soothing the HPA stress response and so much more. Want more PREMIUM CONTENT YOU HEARD IN TODAY'S EPISODE? Get inside the vault!Show notes put you in closer touch with everything that's happening right now in the new age of lifestyle medicine.    -- New prevention strategies    -- New functional medicine testing     -- New holistic treatments     -- New evidence on supplements - what you need and why In each PDF you'll get premium content filled with science-based evidence in clean, organized, easy to follow format.Best of all, your show notes will help you get even more informed and inspired.It's time to close the gap between knowing and doing. Don't you owe it to yourself to have the best information possible to live a longer and healthier life? Get Inside the Vault HERE:  https://sevahealthgroup.com/product/podcast-show-notes-all-access-vault-pass/ Get Today's PREMIUM  Show Notes HERE: https://sevahealthgroup.com/product/7-secrets-to-keeping-mens-hormones-in-balance/ INCLUDES YOUR FREE BONUS: Creating My Success, Fit & Functional For Life Healthy Habit Tracker  --------------------------Stay Connected To Angel:Subscribe to Angel's Newsletter & Mailing List:  Healthy Housecalls With AngelChange Your Life, Not Just Your Symptoms! Join Us Here: Get Fit & Functional For LifeFollow  Angel on LinkedInFollow Angel on FaceBook Get Angel's Valuable  Resources:DOWNLOAD YOUR FREE SUCCESS TRACKER NOW: Creating My Success, Fit & Functional For Life Healthy Habit Tracker (click the link)ENROLL IN OUR FREE RETREAT TODAY: What area of your life needs the most attention today?   Find out in this free 7-day email course and learn how radical self-compassion can help you recognize signs of burnout, reverse damage caused by stress, and restore your physical, mental, and spiritual health (click the link)Schedule your COMPLIMENTARY Vision to Victory Coaching Session 

Summary This episode (#12) continues the overview of neurosteroids and their critical function in the protection and enhancement of cognitive function. In episode #11, I reviewed the role of “Testosterone, Progesterone and Allopregnanolone—Critical and Timely Neurosteroid Interventions in the Risk Reduction of Alzheimer's Disease.”, and this podcast will add DHEA and pregnenolone to that overview. The focus today will center around the pressing fact that the declines of steroid hormones such as DHEA and pregnenolone have pronounced effects on brain and longevity wellness. DHEA, pregnenolone, estrogen and progesterone and other hormones in anti-aging therapies has long been sought after by people striving for an increased quality of life and the enhancement of a more youthful vitality. Additionally, age-related decline of DHEA, and abnormal cortisol levels, have long been associated with and increased risk for numerous health disorders including insulin resistance and type 2 diabetes, obesity, osteoporosis, cardiovascular disease, hypertension, depression, and cognitive decline and dementia. Plus, in the brain chronic stress and excess cortisol patterns is linked to the demise of newly formed brain cells and the inhibition of a critical phenomenon associated with it—neurogenesis, in a key learning and memory center—the hippocampus. The inhibition of neurogenesis (the generation of new brain cells) by excess cortisol is a significant risk associated with brain and hippocampal shrinkage, and the depression and dementia associated with prolonged stress patterns. On the other hand, low cortisol in aging individuals is linked to memory problems and depression as normal cortisol function in the brain is in fact required for cortisol activation of glucocorticoid receptors and memory acquisition and consolidation. Optimizing pathways that promote neurogenesis and neuroplasticity as we age is vital to longevity wellness and healthy cognitive function. The generation and development of new nerve cells such as neurons in the brain, or neurogenesis, occurs throughout one's lifetime and is perhaps the most critical phenomenon associated with modifying the risk for cognitive decline and dementia in aging. Many studies have shown that higher levels of neurosteroids such as DHEA, and allopregnanolone that is metabolized from progesterone and pregenenolone, induce neurogenesis and are protective against memory decline associated with normal aging and Alzheimer's disease. In this episode I also describe the role of DHEA and pregnenolone in modulating key synaptic receptors—NMDA, AMPA and GABA, which is a key dynamic in modulating calcium-related excitotoxicity. Excitotoxicity is a hallmark pathological insult linked to the progression of Alzheimer's disease. DHEA, pregnenolone and their sulfated forms—DHEAS and Pregnenolone sulfate (PREGS), are protective factors against excitotoxic events. Both DHEA and pregnenolone and their derivatives also provide anti-inflammatory and antioxidant protection and counter beta-amyloid induced neurotoxicity. There is more so please listen in to get the rest of this essential overview on neuroteroids in longevity wellness and the protection against cognitive decline and the risk for dementia. God bless! Ralph Sanchez, MTCM, CNS, D.Hom https://www.TheAlzheimersSolution.com https://www.facebook.com/TheAlzheimersSolution/ https://www.linkedin.com/in/ralph-sanchez/ https://www.instagram.com/alzheimers_solution/ https://twitter.com/RalphSanchez  

We're getting out of the shallow end of endocrine essentials and going deep into some controversial topics—so buckle up. Our Ask the Experts series is back this week with Tom Guilliams explaining the truth about Adrenal Fatigue and answering the question: Does chronic stress really “steal” pregnenolone to make cortisol? 

We see this often with clients with high stress lives that sex hormones are negatively impacted and it's important to understand from a physiological perspective what is taking place. We'll chat about the pregnenolone steal myth when it comes to this topic, cholesterol considerations, and more! Topics include:   - Stress and Sex Hormone Changes - Pregnenolone Steal Myth - Main Issues with Pregnenolone Steal - Manufacturing Factory Example - The Cholesterol Component - FNMS Program - Please Share, Rate, and Review ----------  My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization  Learn More www.sammillerscience.com/FNMS2022  ----------  No-Cost Coaching Resources for Our Listeners The Check-In Checklist: www.Sammillerscience.com/checklist  The Metabolism School Mini Series: www.sammillerscience.com/metabolism ----------  Stay Connected Instagram: @sammillerscience Facebook: The Nutrition Coaching Collaborative Community  https://www.facebook.com/groups/nutritioncoachingcollaborative TikTok: @sammillerscience - https://vm.tiktok.com/ZTdPVQtMH/ ---------- “This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at team@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast.”

This is our first english episode. Daniel, one of the Co-Founders of Lichtblock speaks with Elliot in a really detailed podcast about the importance of thiamin, protocols about supplementation, hydration and many more topics! Look for the timestamps! Even for people who know a lot about this topic you will find information you might not know. 00:00 Introduction 02:47 How does Elliot work? Who does he take on as a client? 09:00 Blueblocking glasses and foundation work 14:30 Intro vitamins, minerals, macro and micronutrients, 19:30 What creates deficiencies? Especially Thiamin 26:30 Why is thiamin important? 40:10 Pregnenolone steal? Does it exist? 42:20 The body decides, Vitamin D minefield? 45:07 Signs of deficiency! Brainstem 48:30 Homeostasis vs homeodynamics 52:00 Cold hands, digestions issues, circulation and other signs 58:10 Its your brain, relation to chiropractic and primitive reflexes 01:08:50 What is real hydration? Dehydration? 01:11:30 Water in test tube vs water in the body 01:25:10 Thiamin deficiency causes potassium retention problems? 01:30:00 Low Thiamin, low magnesium? 01:34:00 Glucose in the brain and EMF 01:39:00 EMFs intracellular dehydration? 01:45:00 Hyperexcited neurons? 01:47:00 High dosages of thiamin and traumatic brain injury 01:51:00 Which forms of thiamin? 02:03:00 Deficiency a month to a year vs medical usage 02:05:00 B Complex? 02:09:00 Fibromyalgia, Parkinsons, Alzheimer 02:13:00 TTFD and Derrick Lonsdale 02:26:00 Fish oil, Vitamin A toxicity, copper, coffee in the morning Find out more about Elliot on https://www.eonutrition.co.uk You can also purchase his thiamin protocol ebook, which is really helpful when it comes to guiding you in how to supplement it. His supplement company is: https://www.objectivenutrients.com Get 10 percent on your order at lichtblock.shop with “LB10” for high quality blueblockers. Follow us on Instagram @lichtblock.shop or visit us on our English website: en.lichtblock.shop Host: Daniel Sentker – Chiropraktor M.Sc., Heilpraktiker, Speaker and Co-Founder of Lichtblock: https://phoenix-chiropraktik.de Instagram: @daniel.sentker Lichtblock®: https://lichtblock.shop Instagram: @lichtblock.shop The Podcast: Lichtblock Professionals We introduce you to experts who can give you exciting insights and tips from the field and thus create new ways of thinking for you. The focus is on the areas of light, sleep and lifestyle. We also cover topics such as exercise, nutrition and mindset. With our podcast we want to support you in finding the best compromise between the digital world and nature. Red light and blueblocker glasses can be of great help. But the focus is not on our own products, we mainly want to promote a positive and healthy lifestyle. If you have any questions, comments or ideas, feel free to drop us a line at podcast@lichtblock.shop or on Instagram @lichtblock.shop

Tune in to the hormones mashup episode where we've combined our top expert interviews to shine light on ways to balance your health. You'll find out what to do when you are estrogen dominant, when you may need hormonal replacement therapy, and what happens when testosterone is running amock. You'll discover how stress affects your menstrual cycle, what DHEA and Pregnenolone are doing to your body, and how to manage your levels of testosterone. We'd like to thank our sponsors, Athletic Greens - redeem an exclusive offer here: athleticgreens.com/stephanieLMNT Electrolytes - A FREE 7-flavor sample pack! - https://www.drinklmnt.com/DrEstimaOrion Red Light Therapy - get 10% off your order with Promo Code “STEPHANIE10” https://www.orionrlt.ca/?ref=StephanieLumen - get $25 off your order with Promo Code “DRSTEPHANIE25” https://www.lumen.me/?fid=1799Ancestral Supplements - Use Promo Code “ASA10” for 10% off any purchase https://shop.ancestralsupplements.com/discount/Tribe10?rfsn=5900205.652074&utm_source=refersion&utm_medium=affiliate&utm_campaign=5900205.652074PRIMEADINE - get 10% Off your Order with Promo Code “DRSTEPHANIE10” - https://oxfordhealthspan.com/products/best-spermidine-supplement And follow me on social:Instagram: https://www.instagram.com/dr.stephanie.estimaFacebook: https://www.facebook.com/groups/betterwithdrstephanie Join the Hello Betty Community here - https://hellobetty.club/membership/ Episode Overview: 7:45 Introduction12:42 Estrogen Dominance With Dr. Sara Gottfried18:41 Hormonal Replacement Therapy With Dr. Felice Gersh23:44 Androgen and Estrogen Dominance with Dr. Mohammed Mansoor33:46 How Stress Affects Your Menstrual Cycle With Dr. Carrie Jones38:36 Stress and Estrogen Dominance With  Dr. Mariza Snyder44:19 DHEA and Pregnenolone with Nicole Jardim49:10 Testosterone In Women With Dr. Sara Gottfried

Lots of great questions sent in for this Q&A with Karen; Livia Hi Karen! I've been looking all over for info on increasing testosterone. Mine has been incredibly low. I'm 34, not menopausal, been eating keto for years, I've tested when I did carnivore a year ago and again and still low. I eat lots of red meat, liver. Not sure what else to do. DHEA was in “normal” range and so were B vitamins. Is there anything I'm missing? Elda Is oral progesterone or cream better Jackie How the heck do I get some energy back so I can eat well and exercise? It's so difficult to get motivated and the weight is piling on. PS I love you Karen, you are saving my life

Understanding how to fix your period and optimize your menstrual cycle. We discuss the four phases of the menstrual cycle, typical menstruation blood flow, and ovulation. We talk about the hormonal hierarchy, cervical fluid, how stress affects your cycle, and indicators of these stressors. Join BettyYoga Here Thank you to our sponsors: Athletic Greens - athleticgreens.com/stephanieOrion Red Light Therapy - Use promo code STEPHANIE10 for 10% off - https://www.orionrlt.ca/?ref=StephanieLumen - Use promo code DRSTEPHANIE25 for $25 Dollars off - https://www.lumen.me/LMNT Electrolytes - FREE 7 flavor sample pack at http://drinklmnt.com/DrEstimaPRIMADINE - Code DRSTEPHANIE10 for 10% off - https://oxfordhealthspan.com/discount/DRSTEPHANIE10Ancestral Supplements - Use Promo code ASA10 takes 10% off any purchase - https://ancestral-supplements.myshopify.com/?rfsn=5900205.652074&utm_source=refersion&utm_medium=affiliate&utm_campaign=5900205.652074Some of the links above are affiliate links. Making a purchase through these links won't cost you anything (and in many cases give you a discount), but we will receive a small commission. This is an easy, free way of supporting the podcast. Thank you! Connect With Nicole: https://nicolejardim.com/https://www.fixyourperiod.com/https://www.instagram.com/nicolemjardim Social: https://www.instagram.com/dr.stephanie.estimahttps://www.facebook.com/groups/betterwithdrstephanie Membership Site:https://hellobetty.club/  Episode Overview: 6:18 Introduction9:40 Welcoming Nicole & Origin Story18:16 Four Phases Of The Menstrual Cycle29:44 Menstruation Blood Flow35:36 The Pill and Pregnancy39:39 Ovulation47:53 How Can Stress Affect Menstrual cycle56:51 Indicators of Stress1:02:01 Role Of Boundaries1:1:26 Pregnenolone1:15:03 DHEA1:17:30 Secondary Dysmenorrhea1:25:20 Nicole's Favourite Ways To Optimize Cycle1:30:40 Conclusion More information about the book at The Betty Body Book Join the Betty Booty ChallengeJoin the Hello Betty Community here! 

00:00 - Start, why are we doing a fundraiser? 01:58 - Trestolone 7α-methyl-19-nortestosterone (MENT), activation of the androgen receptor, adding a methyl group to a steroid makes it risky 04:46 - What would Ray do if he had Crohn's disease? Mycobacteria, supplementing with cellulose 09:56 - Cortisol blockers for weight loss? Progesterone, thyroid 10:38 - Do you want to increase ceruloplasmin? Copper toxicity 12:55 - Does nitric oxide work like viagra? 14:36 - Lactose-free milk and is aspirin safe to take every day? 15:43 - Low sperm count, varicocele, aspirin, progesterone, thyroid, testosterone, estrogen 18:14 - Ray's thoughts on ivermectin, vitamin D, coronavirus 22:46 - Hypothyroidism in children? 24:53 - Can thyroid hormone lower the temperature? 28:20 - Why are people getting flu and cold symptoms right now? 30:03 - Is vaccination a tradeoff? 32:19 - What steroids would be useful for building big muscles? Testosterone, estrogen, DHEA, 'thyroid is the basic anabolic hormone' 36:52 - Sleep apnea, CPAP, CO2, hypothyroidism, progesterone, acetazolamide 40:26 - Diabetic pain in the feet, T4 only therapy, thyroid gland removal, armour, cynoplus, cynomel 43:02 - Progest-E by Kenogen, email Katherine at kenogen@gmail.com, progesterone as a basic stabilizing factor 44:58 - Ray's thoughts on ethically composing a "cosmic diet" 46:25 - Benign tumor metabolism, progesterone, fibrosis, estrogen, nitric oxide 48:38 - Gynecomastia, vitamin D, progesterone, thyroid, aspirin 49:25 - When did the U.S. transform into an empire? 52:26 - Inability to ejaculate and get an erection, getting blood tests, low heart rate, hypothyroidism 54:49 - Herbs for DHT production? 55:29 - Can T3 harm the thyroid gland if used chronically? 58:17 - Pregnenolone, adrenal suppression, progesterone, stress 01:02:29 - Increasing libido and energy in a young woman after childbirth, vitamin D, calcium, thyroid 01:03:31 - How to reverse the aging process? CO2 as a cardinal adsorbent, flavanoids, fisetin 01:11:26 - Raising levels of the ACE2 enzyme for health, anti-viral effects of progesterone 01:14:06 - Getting rid of acne scars 01:15:12 - Taking thyroid but the morning temperature isn't increasing 01:16:01 - Diabetes, swollen purple legs, and significant edema, vitamin D, calcium, progesterone, thyroid, a lower-fat diet 01:17:27 - Best things to increase mitochondrial function, CO2, angiotensin inhibitors 01:18:17 - Correcting a thyroid nodule, TSH 01:19:03 - Excess saliva 01:19:35 - 16-year old breast cancer, estrogen, progesterone, aspirin, thyroid 01:20:18 - T3 and body odor, sulfur soap 01:21:09 - Nicotine as a prometabolic substance? 01:22:49 - How to lengthen the luteal phase? 01:23:45 - A daily progesterone amount for men? 01:25:20 - Is the Herxheimer reaction real? Harry Rubin's findings about cancer treatment 01:29:15 - A bioenergetic view of THC and CBD? 01:31:10 - Ray's essential 'prepper' food items 01:34:16 - Lump in the throat from cynoplus and cynomel, how much is too much with T3? Does Ray chew the cynoplus/cynomel? 01:36:16 - Varicose veins from progesterone or pregnenolone? What's a big dose of progesterone? 01:39:16 - What does Ray think of the croissant diet? 01:40:29 - What amount of alcohol is enough for lipofuscin? 01:41:18 - How to restore the outer layer of the adrenal gland? 01:42:12 - Can the temperature and pulse be maintained by stress? How long does it take to adapt to a thyroid supplement? 01:45:19 - What is Ray working on right now? 01:46:45 - Magnetofection? 01:48:04 - How to use progesterone to post-pone menopause? 01:49:36 - Benefits of allopregnanolone? 01:49:51 - Very dry palms, hypothyroidism, sebum, sweat 01:50:31 - How to tell if sugar is converting into CO2 or lactic acid? 01:50:59 - 1000 calories for weight loss? RU486 cortisol blocker, how many calories to eat? 01:53:44 - Kids dying as the result of vaccination

Using hormone supplements can be tricky. It's too easy to overuse or use them incorrectly, resulting in side effects and even a worsening of your overall condition. But here's how to use DHEA and Pregnenolone supplements correctly and in a way that supports your adrenal function. 1:40 - Pregnenolone the Grandmother of Hormones4:00 - How Cortisol and Stress affects Lab results6:30 - How to Supplement DHEA and Pregnenolone correctly9:00 - How your adrenals make Cortisol and DHEA10:50 - What to do for Low DHEA12:40 - Side effects of DHEA14:40 - High DHEA CausesTrying to find an integrative medicine or functional medicine doctor who understands what you're going through? Lam Clinic does Telemedicine all over the world and is only a phone call away. 1. Educate yourself by visiting our website: www.lamclinic.com2. Call our office at 714-709-8000 to schedule an appointment. FIND US ONLINE HERE: » Website: https://www.lamclinic.com/» Facebook: https://www.facebook.com/lamclinic» Instagram: https://www.instagram.com/lam_clinic/» Tiktok: https://www.tiktok.com/@lamclinic» YouTube: https://www.youtube.com/channel/UCWtdb4L5h5EuxKvkNq3M7yw

"Feel Strong & Look Great, Clear Skin At Your Ideal Weight: Loving Life" watch the video here: youtu.be/DjVZuxB6wJU *** Apply for a coaching program: nickdelgado.com/ *** Subscribe to our YouTube channel: www.youtube.com/delgadovideo *** Shop here for the supplements: estroblock.com/

In episode 73 of Coaches Corner, we dive right into it and answer a great question Paul had from coachescorneru.com. From there we move into the rest of the great questions. We cover a lot this week and we are also doing a giveaway!! Subscribe to iTunes, Soundcloud, and Stitcher at Coaches Corner. If you like the podcast leave a review and a 5-star rating on iTunes. Share it with a friend and all over social media. Sponsors: subjectzerosupps.com -Code beyond 10 for discount coachescorneru.com baconandbarbells.co -Code paul10 for discount 1-lifeinc.com Time Stamps: 00:00 Intro 07:00 Training to failure - when to add in intensifiers 15:29 Using your assistance work as prehab - tissue resiliency 21:03 Should nutrition change during deload weeks 31:48 Healthy body fat level for strength athletes 41:14 Is DHEA & Pregnenolone beneficial for TRT ‘blasting and cruising’ 47:18 Dealing with side effects 51:56 Cardio for fat loss vs. cardio for heart health 1:00:30 Coaches Corner University Giveaway

Timestamps: 10:43 Is taking 500mg of caffeine bad in your opinion? 12:33 When will Sear be back in stock? 13:04 Why the chinstrap in 2021? 14:36 Are you coming to The Shop Gym Ashburn this weekend? 15:42 Can we get a Hawaiian Punch 'Merica Energy flavor? 16:14 When is the next big launch you're extremely excited about? 21:07 Is Napalm comparable to OxyShred or Opti Burn? 21:43 What is your opinion on flavor collaboration with other companies? 25:34 Is the Gains Tour coming back? 26:40 What kind of value do you place on supplementation for someone training to get fit and look good? 30:57 Did you ever have a personal trainer in your fitness career? 31:11 What is the best compound movement for side delts? 32:31 Do you do 25 sets/week for smaller muscles too? 33:06 How often should you feel sore and how important is it that you do? 34:08 Does your wife still train, and if so, what supplements does she take? 34:55 What pre-workout should I try for hypertrophy training? 35:20 Is Core Post good to take after a workout when you're dieting? 36:16 Training vs. working out - is there a difference? 37:11 How many pull-ups should I do for my first set? 37:41 Is DHEA a supplement you would recommend or use? 38:38 Phosphatidic acid or Laxogenin for natural, lean gains? 39:40 How was it doing Fouad's podcast? Do you read the YouTube comments after? 41:12 Can you elaborate on mixing up the texture with the new Core Balls? 44:38 Will you be by my house by Natural Body in Queens in the summer? 47:27 What ingredient in the ARN vitamin stack could make me feel nauseous? 48:18 Do you combine DHEA and Pregnenolone? 48:28 Best time to take Sear on a rest day? 50:10 Besides being ready 3-4 weeks early, do you have any general advice for a first time natural competitor? 51:19 Training sources for the gym? 51:40 What led you to the bro split with high volume? 52:28 Do you have plans on developing businesses outside of the fitness supplement industry? 53:28 Why are you passionate about fitness and what led you there? 58:48 Do you need to cycle Poise? 1:00:30 Whey protein as snacks, whey isolate as post-workout, casein before bed - is this too much powder? 1:00:51 How long before you go to bed do you stop eating? Is there a reason or is this just routine? 1:03:05 'Merica Energy launching with 5 or 6 flavors? 1:03:32 With the move to North Carolina, are you going to keep the Mercedes AMG?

"Feel Strong & Look Great, Clear Skin At Your Ideal Weight: Loving Life" *** Apply for a coaching program: nickdelgado.com/ *** Subscribe to our YouTube channel: www.youtube.com/delgadovideo *** Shop here for the supplements: estroblock.com/

The Pregnenolone Steal is something that most of us women deal with at one point or another in our lives. We're stressed to the max in so many areas of our lives and wonder why our hormones are totally out of balance. In this episode I explain what stress is like for your body, what the Pregnenolone Steal is, and how you can fix is. Connect with me via instagram @thisgirlaudra, send me an email to thisgirlaudra@gmail.com, visit my website www.thisgirlaudra.com and see my YouTube videos on "This Girl Audra."

00:00 - Setup music 08:14 - Start and catch up 10:45 - Other life in the universe? 16:38 - Process theology, radical empiricism 18:19 - Ideologues in cosmology 20:10 - Halton Arp, Frederick Soddy 22:11 - N.A. Kozyrev 24:06 - H.C. Dudley, neutrino sea 26:04 - Where is matter from? 28:09 - David Bohm 29:22 - Do humans create matter? 32:08 - Sensory deprivation experiments 32:31 - What do you see when you close your eyes? 41:02 - Are serotonin and melatonin necessary for dreaming? 42:46 - Melatonin in trauma 43:28 - Symbols of an Alien Sky documentary by David Talbott, Vladimir Vernadsky, Immanuel Velikovsky 45:40 - Cosmic Clocks by Michel Gauquelin, H.C. Dudley, nuclear decay 53:02 - Is carbon dating accurate? 54:58 - Is nuclear power inherently dangerous? 56:30 - Did advanced civilizations exist? 57:44 - Coral Castle by Edward Leedskalnin 58:43 - Could humanity solve its own problems if there was no authoritarian influence? 59:36 - Does Ray remember a time when there was more liberty? 01:00:27 - Was there a natural factor that contributed to the current increase in evil? 01:02:00 - Evil is like glycolysis 01:02:39 - Klaus Schwab and His Great Fascist Reset https://off-guardian.org/2020/10/12/klaus-schwab-his-great-fascist-reset/ 01:07:22 - Crimes against humanity by Reiner Fuellmich 01:08:25 - The legal system a way to interfere with the great reset? 01:09:33 - The military is involved in every vaccine trial, biological warfare, China 01:17:08 - "The media prevents you from knowing how you're being dominated, by keeping the CIA's secrets. The media and the CIA are same thing." Douglas Valentine 01:18:55 - Adverse events in vaccine trials 01:20:11 - What causes polio? 01:23:10 - Endotoxin and Guillain-Barré syndrome 01:24:04 - Is aluminum more dangerous than endotoxin as an adjuvant? 01:24:56 - The physiology of being offended 01:27:24 - Low metabolism and subordination 01:28:46 - Body Pleasure and The Origins of Violence James W. Prescott (1975) 01:32:25 - The weaponization of sex 01:33:36 - "The use of noncommunicative jargon can be an indication of a personality disorder." Ray Peat 01:35:32 - What can shift a person away from authoritarianism? 01:36:36 - When did blue lights replace incandescent lights in hospitals? 01:38:22 - Plastics, static discharge, toxic chemicals in plastic 01:40:36 - In defense of Mexican coke: sucrose, coca leaf extract, caffeine, 4-methylimidazole, potassium content 01:47:13 - Fresh sweet fruit juice preferable to coke, puritanical nutritionism 01:49:00 - Pepsi vs. coke 01:50:00 - "When people supplement thyroid and eat liver once or twice a week, their acne and dandruff (and many other problems) usually clear up very quickly..." Ray Peat (2011) 01:52:05 - How many "grains" of thyroid is in a cynoplus tablet? 01:58:55 - Vaccination against rabies virus 02:02:13 - Pregnenolone contamination

Do you suffer from:Insomnia or sleep disturbance, low libido, mood changes, anxiety and irritability, headaches and migraines, weight gain, irregular menstrual cycles? If so, these could be signs you have low progesterone. In this episode bikini coaches @chrisnicole_ifbbpro and @amyehinger address ways to increase progesterone naturally. To start, what is progesterone? Progesterone is a female sex hormone that prepares the uterus for pregnancy. Progesterone is the main hormone of the luteal phase which begins following ovulation (around day 14 of your cycle). The drop in progesterone (and estrogen) at the end of your luteal phase triggers the beginning of your cycle. Reasons you might have low progesterone 1. Stress Your body will always choose survival over procreation. This means you will preferentially make cortisol over progesterone when exposed to chronic stress. Pregnenolone, which I like to think of as the “mama hormone” gives birth to both progesterone and cortisol, as well as other hormones. In times of stress, pregnenolone will be shunted to make cortisol at the expense of progesterone. This is what is known as the “pregnenolone steal.” In addition, cortisol blocks progesterone receptors, which means that you can not efficiently use the progesterone you are making.  2. Hypothyroidism Remember pregnenolone?  To even make the molecule you need to create progesterone you must first have adequate thyroid hormone.  3. PCOS Rises in testosterone mean lower levels of progesterone. Making sure you’re producing adequate progesterone is essential in order to ovulate. Without ovulation, not only is it difficult for your body to adequately clear the uterine lining during menses, but it’s impossible to get pregnant. And it’s important to understand that even if you’re having a period, it doesn’t mean you’re ovulating!  4. Age After age 35, there is an inevitable decline in progesterone.  5. Elevated prolactin Prolactin is the hormone that triggers lactation but can rise in non-lactating women as well. This is a problem because high levels of prolactin can interfere with progesterone production and inhibit ovulation. High prolactin can be the result of a poor diet, stressful lifestyle or something more serious so you definitely want to get this checked out.  6. Estrogen dominance occurs whenever a woman produces too much estrogen relative to her progesterone levels. Estrogen dominance can occur during perimenopause or menopause but is becoming more prevalent among women of childbearing age. Excess body fat, chronic stress, and a diet high in sugar and processed starchy carbs can contribute to blood sugar imbalance and hormone dysregulation. When progesterone is low due to estrogen dominance, you’ll likely experience other symptoms like fluid retention and irritability. How to increase progesterone 1. Manage stress As mentioned above, chronic stress increases the secretion of cortisol and adrenaline at the expense of sex hormones like progesterone.Try stress management techniques such as deep breathing, mindfulness, or just walking the dog or talking with a friend.  2. Progesterone foods – Eat fat! Cholesterol is necessary for the synthesis of pregnenolone (the “mama” hormone), which in turn makes progesterone. Cholesterol is also necessary for the production of thyroid hormone!  Fat will also help to balance blood sugar. Insulin sensitivity or blood sugar imbalance has deleterious effects on your hormones. Studies suggest that improving insulin sensitivity can dramatically increase progesterone levels in those with luteal phase defects.(1)  Fat from trusted sources of meat, lard, fatty fish, and plant-derived fats like coconut oil, olive oil, olives, nuts, seeds, and avocado are all good progesterone food choices . Women wanting to improve their hormones should eat at least 2 tablespoons of fat at every meal to support natural hormone balance. 3. Vitex agnus-castus (Chaste tree berry) Vitex raises progesterone by stimulating the secretion of Luteinizing Hormone (LH) from the brain, which then stimulates ovaries to produce progesterone. Vitex has also been shown to reduce prolactin secretion while raising progesterone levels.  4. Green tea Green tea helps with estrogen metabolism, which is critical when dealing with estrogen dominance and lowered estrogen levels are associated with fewer incidences of cancer, especially breast cancer.  5. Rhodiola rosea Rhodiola helps to balance cortisol output, which indirectly supports healthy progesterone production.  6. Zinc Zinc increases follicle stimulating hormone (FSH), which supports healthy ovulation, which triggers the ovaries to produce progesterone.  Get plenty of zinc-rich foods like oysters, herring, beef, lamb, pork, liver, egg yolks, oats, pecans, Brazil nuts, pumpkin seeds, ginger root, mustard, chilli powder, peas, carrots, beets, and cabbage. 7. Magnesium Magnesium is involved in many of the body’s reactions and is essential to adrenal health, which is essential for healthy hormone production! Supplement or eat plenty dark green vegetables, almonds, pecans, cashews, brazil nuts, seeds, legumes, brown rice, avocado, and dried apricots.  8. Vitamin B6 B6 is involved in estrogen metabolism and can easily become depleted if estrogen dominance is a problem. Vitamin B6 possesses “progesterone-like effects” and has been shown to reduce estrogen while increasing progesterone levels.And definitely eat some of the following B6-rich foods: liver and other organ meats, fish, poultry, egg yolk, dried beans, peanuts, walnuts, banana, prunes, potatoes, cauliflower, cabbage, and avocado.  9. Vitamin C  Antioxidants like vitamin C may increase and intensify the effects of progesterone. Vitamin C has also been shown to raise progesterone levels and resolve luteal phase defects, resulting in improved fertility.  Or, you can try these high-vitamin C foods: Citrus fruits, strawberries, mango, papaya, watermelon, tomatoes, broccoli. Brussels sprouts, cauliflower, cabbage, and spinach. Supplements to order: Harmony https://1stphorm.com/products/harmony/?a_aid=glamgirlbikini DB Goddess  https://1stphorm.com/products/1-db-goddess/?a_aid=glamgirlbikini&a_aid=glamgirlbikini&a_bid=4b7ce806&chan=AE  Core-21 https://1stphorm.com/products/core-21/?a_aid=glamgirlbikini&a_aid=glamgirlbikini&a_bid=4b7ce806&chan=AE You can find us on Instagram @preplifepodcast and @glamgirlbikini You can apply for the team by clicking the link:https://www.glamgirlbikini.com/get-started/  

In this Q & A episode with Brandon and Ryan, they discuss whether Pregnenolone, Progesterone, and DHEA should be discontinued after 12 weeks of use, if there are there any plans for a test to replace the BH101 yet, whether coffee enemas should only be used to support a liver cleanse or can they be used as ongoing liver support, and more! Join FDN founder Reed Davis, FDN Mentors, and Special Guests to learn about functional lab testing and data-driven protocols to confidently solve health issues and grow your health coaching business. Submit questions in advance, or better yet, call the show LIVE and join the discussion by calling (347) 637-1378. The live show takes place every Friday at 11 am PST/ 2 pm EST.  If you are interested in becoming a Functional Diagnostic Nutrition ® Health Coach go to https://fdn.today/show

Question: The use of pregnenolone to manage perimenopausal symptoms, particularly insomnia. Carrie: Well, so here's the thing about pregnenolone. Oral or sublingual, so if you've got drops or little tables you suck on. Pregnenolone and progesterone, when they go through first pass, so you swallow them and then you go through first pass, they turn into other metabolites. One is called allo, which is short for allopregnanolone. Allo binds to your GABA receptors in your brain. Allo can cross the blood-brain barrier, binds to GABA. GABA, of course, is your calming, relaxing, everything is going to be okay hormone. Pregnenolone, oral pregnenolone and oral progesterone actually work on the anxiety and on the insomnia from a GABA point of view. This Q&A can also be found as part of a much longer episode, here: https://chrismasterjohnphd.com/podcast/2019/10/19/ask-us-anything-hormones-dr-carrie-jones-may-10-2019 If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a ====== DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. PLEASE NOTE: As a result of the COVID-19 crisis and the time I am committing to staying on top of relevant research, as well as the high volume of questions I receive, it may take me extra time to respond to questions here. For an up-to-date list of where I respond to questions most quickly, please see the contact page on chrismasterjohnphd.com. =======

Chris Marx, MD and Jennifer Naylor, PhD join JAMA Network editors to discuss a randomized clinical trial investigating the use of pregnenolone vs placebo for low back pain among Iraq- and Afghanistan-era US military veterans. Read the article here: https://ja.ma/38FNlte. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Austin finally returns to the podcast with harrowing tales of almost being eaten by a wolf. Today we discuss a new NEJM paper about long acting injectable therapy for HIV and a new JAMA paper about pregnenolone, a neurosteroid that may help treat the scourge of primary care: chronic low back pain. Long Acting Cabotegravir and Rilpivirine for HIV-1Pregnenolone vs Placebo for Chronic Low Back Pain in Veterans Music from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)

There's been a growing amount of hype around the "Deca only cycle". While it is most commonly referred to as the Deca only cycle, it is actually based on the compound Nandrolone being used on its own. The decanoate ester being abbreviated as "Deca" has just become synonymous nowadays in the bodybuilding community with Nandrolone itself. Seeing the potential merits of Nandrolone as a makeshift hormone replacement therapy alternative to Testosterone, I stopped using Testosterone and instead started using Nandrolone on its own with exogenous Estradiol for 3 months and paid over $1000 for an elaborate blood panel to assess how it affected my health markers. https://youtu.be/kLScNddgkks How Nandrolone Could Potentially Be A Superior HRT Alternative To Testosterone The primitive thought process is that Nandrolone used in conjunction with Testosterone will lead to horrible side effects, but Nandrolone used on its own will just result in all of the benefits of steroids with a near absence of the androgenic or estrogenic side effects associated with Testosterone use. In reality, it's a lot more nuanced than that. The reason why I found this experiment worth pursuing is the lack of androgenicity of Nandrolone in the body. Nandrolone 5α-reduces in tissues that express 5α-reductase to the much less androgenic metabolite Dihydronandrolone (DHN). Nandrolone is basically the only anabolic steroid that is going to maintain 100% anabolic activity of the Nandrolone in muscle tissue where you want it, but also be converted into a much less androgenic metabolite with a lower binding affinity in certain areas of the body where you wouldn't want Nandrolone to bind. The two areas of concern for most individuals being hair follicles and skin. By converting to DHN in these areas, Nandrolone (and by extension DHN) causes less hair loss and acne than Testosterone (and by extension DHT). In addition, some men are genetically predisposed to high levels of aromatization and estrogen receptor expression and can't even use TRT doses of Testosterone without experiencing estrogenic side effects. Nandrolone is not a potent substrate for aromatase, and mainly converts to a weaker estrogen called Estrone (Estradiol is about 10-fold more potent than Estrone). Nandrolone is also mildly estrogenic on its own via its ability to act as an estrogen receptor alpha (ERα) agonist [R]. Overall, Nandrolone is much less androgenic and estrogenic than Testosterone, and may provide symptom relief in those seeking a viable hormone replacement therapy alternative. In this context, Nandrolone may also have great potential as an efficacious alternative to Testosterone as an anabolic agent for some individuals who are prone to androgenic and/or estrogenic side effects. The Neurotoxicity And Cardiotoxicity Of Nandrolone Based on the limited data available, Nandrolone has shown to be more deleterious to cardiovascular and neurological health than testosterone. https://www.youtube.com/watch?v=Gv_v0mJy6Bg By extrapolating the data, we start to get a clearer picture as to why this likely is. Nandrolone is mildly estrogenic on its own, and it does not aromatize nearly enough to create as much Estradiol as Testosterone does. Comparing the effect of testosterone with that of 19-nortestosterone (Nandrolone) and Stanozolol (Winstrol) on neurotoxicity we can clearly see that Estrogen is what protects neurons in the brain, not Testosterone itself. In this study, a physiologic dosage of Testosterone was neuroprotective [R]. Testosterone only amplified neurotoxicity at supraphysiological dosages. The neuroprotective effect of a physiologic dosage of Testosterone was completely eliminated when the aromatase inhibitor Anastrozole (Arimidex) was co-administered, suggesting that the intrinsic toxicity of Testosterone as an androgen is only counterbalanced by its aromatization into 17β-estradiol. As opposed to testosterone, Nandrolone does not appear to aromatize sufficiently into estrogen. As you would expect, Nandrolone was neurotoxic at every single dose evaluated regardless of Arimidex being co-administered or not. If Nandrolone was inherently able to provide enough estrogen receptor alpha (ERα) activation to balance out its androgenicity without even requiring aromatization (it acts as an estrogen on its own to some extent), we would see a neuroprotective effect at equivalent dosages to a physiologic concentration of Testosterone when no AI is used, but that does not appear to be the case either. The anti-androgen flutamide attenuated the neurotoxicity of all three androgens, thus further reinforcing that physiologic dosages of androgens without a sufficient amount of opposing estrogens, or supraphysiological dosages of androgens may facilitate neuronal death. I suspect that the same applies for the inherent cardiotoxicity of Nandrolone as well. Just because you can get your Estradiol levels up to 15 pg/mL with a gram of Deca only, that ratio of androgens to estrogen in the body is way off of what would otherwise be optimal for health based on what I've seen. This is reinforced by the fact that Flutamide (an anti-androgen) was able to attenuate the neurotoxicity of Nandrolone. By preventing Nandrolone from binding to androgen receptors, it is no longer able to transcribe its effects in tissues. Hair loss and acne are one thing, cardiotoxicity and neurotoxicity are another thing and should ultimately take precedence obviously. However, just because Nandrolone monotherapy cannot produce a sufficient ratio of androgens to estrogens, that doesn't mean that there isn't a potential loophole. That loophole is exogenous Estradiol administration. Exogenous Estradiol Use With Nandrolone Only Cycles As we've seen, Estrogen produced via aromatase is what provides neuroprotection from the androgenicity of Testosterone, not the Testosterone itself. We also know that Nandrolone is not able to produce enough estrogenic activity in the body to facilitate this same level of neuroprotection. I theorize that Nandrolone in conjunction with exogenous Estradiol to replace this otherwise missing component could attenuate a significant amount of the deleterious impact Nandrolone has on the heart and brain. In addition, by providing a sufficient amount of exogenous estrogen, libido, muscle growth, fat loss, and several other aspects of health and performance should be more optimized. It isn't a coincidence that cardiovascular disease rates skyrocket once women hit menopause and stop producing Estrogen properly. The same negative effects will apply in men with low Estrogen levels. The lack of sufficient Estrogen is often addressed in Deca only cycles by adding an adjunct anabolic steroid that aromatizes into Estrogen or Estrogen analogs. Obviously for those seeking to minimize androgenic side effects, the ideal way to go about achieving sufficient Estrogen receptor activation is probably not going to be by adding more steroids to their protocol. This is where exogenous Estradiol comes into play, and I believe the majority of Deca only cycles would be more sustainable from a health perspective, and successful in a bodybuilding context as well with its inclusion. I have yet to see one person on a Deca only cycle achieve a sufficient Estradiol level relative to their Nandrolone dosage via a sensitive assay Estradiol blood test. The following blood test result was submitted by an individual on over 1000 mg per week of Deca only. Over a gram of androgens relative to a 19.2 pg/mL Estradiol level is far from ideal in my opinion. I had a good conversation with Vigorous Steve as well about his Deca only cycle experience. He told me that his Estradiol was 12 pg/mL on 1000 mg of Deca per week after 4 weeks, and he ended up adding 25 mg DHEA per day just to bring it up to 25 pg/mL. When it comes to Nandrolone use on its own, most would benefit from more Estrogen in my opinion. My Weekly Nandrolone And Estradiol Dosage For "HRT" Most guys doing Deca only cycles are evaluating Nandrolone at dosages of 600 mg or higher per week for short blasts. My experiment was based on its potential as an alternative long term HRT option for those prone to androgenic side effects. Or alternatively, its potential as a compound to swap to periodically throughout the year from TRT to reverse some of the androgenic side effects of Testosterone and DHT while still maintaining the same amount of muscle mass. Every blood test I've seen of Deca only cycle users was on high doses of Nandrolone without a sufficient amount of Estrogen. I wanted to see how Nandrolone on its own at a "therapeutic dose" would affect my blood work if I had a sufficient amount of Estrogen provided through exogenous Estradiol. Long-term, the only way Nandrolone monotherapy could be even relatively safe in a cardiovascular context would be with exogenous Estradiol supplementation from what I've seen. And even then, I'm sure it has major drawbacks that will likely accumulate over the years. With that being said, it is still something I wanted to explore nonetheless, as it is one of the few compounds that can actually support supraphysiological muscle growth with a relatively minimal impact on androgenic alopecia. Oral micronized Estradiol tablets have quite a few drawbacks. A few of the most notable drawbacks are that oral Estrogen pills can be somewhat liver toxic, they spike SHBG through the roof, and they result in the production of clotting factors in the blood that do not develop with forms of administration that skip the first pass. The two most viable methods of administration that skip the first pass are transdermal topical application, or injection. I chose to topically apply transdermal Estradiol gel (Estrogel) for this experiment. I used 100 mg of Nandrolone phenylpropionate (NPP) per week split into daily injections using an insulin pin rotating between my glutes and ventroglutes. I also applied 2.5 grams of transdermal Estrogel (delivering 1.5 mg Estradiol) to my inner thighs every day for over 3 months straight. Blood Pressure Changes On Nandrolone One of the first things I noticed was that it was a struggle to keep my blood pressure in check on NPP, even at the mild dose I was using. What that was caused by exactly, I'm not sure. I assumed it was Aldosterone prior to this blood work. When I'm on Testosterone, even when I was using TRT as high as 200 mg per week, I could keep my blood pressure at 110/70 with ease. Even if I ate terribly, I could still hold 115/75 without even trying on Testosterone. Within the first week of switching to NPP it became way harder to control my systolic blood pressure. My diastolic blood pressure was fine for the entire 3 months, but my systolic blood pressure would consistently be around 125-128. That is not normal for me, and is borderline stage 1 hypertension. The fact that I even had to try to lower my blood pressure showed to me that Nandrolone is a lot harder to manage in this regard. This is consistent with almost every single person I know who has blasted high doses of Deca. They all had significant issues with blood pressure. Most of the guys who thought they had normal blood pressure were actually stage 1 hypertensive and didn't even realize that their results were indicative of cardiovascular stress. My 125-128 systolic occurred without being in a calorie surplus, without any weight changes, and on what I would consider a very low dose of NPP. The exact same diet, weight, lifestyle, etc. would have me at 110/70 on TRT. Muscle Growth And Strength On Nandrolone I maintained my muscle and do not feel that there was a substantial difference between the anabolic potency of Nandrolone compared to Testosterone. At the very least, the anabolic activity of Nandrolone is comparable to Testosterone, but the androgenic activity is far less than that of Testosterone. In certain contexts for certain individuals, Nandrolone will be the desirable alternative because of this. Reduced Libido On Nandrolone - Deca Dick? My libido was extremely subdued on NPP. That's one of the most obvious things I noticed during my experiment. I had a libido and would still want to have sex, but my libido was much lower than it is on regular TRT. On TRT I can barely go one day without sex before it starts to consume my mind.  On Nandrolone only, I can easily go a couple days barely even thinking about it. However, when it came time to get the job done, I could still get the job done and stay hard the entire time without any issues in erection quality. It was a bit harder to reach orgasm though. On top of the lack of androgenicity causing a reduction in libido, Nandrolone also has progestogenic activity and binds to the Progesterone receptor. Excessive Progesterone is notorious for killing libido and causing erectile dysfunction, and it seems that Nandrolone has similar effects in many individuals via this pathway in conjunction with its 5α-reduction into DHN. My drive was also lower, and I felt less aggressive overall. In many individuals Testosterone and DHT levels will strongly influence libido, drive, aggression, motivation and productivity. Personally, even if I have that support via DHT or DHT derivatives, the increased motivation and drive is actually more counterproductive in a work productivity context because my libido gets way too high. Even when I had high testosterone levels and 0 DHT in my body I still had sex on my mind far more than I would like. When that happens, I can barely get anything done, and then I end up depleting myself of energy for the day through excessive sex. The subdued and normalized libido on Nandrolone is welcomed for me because of this. I don't think this is necessarily just because I'm a good responder to Nandrolone, I think it has more so to do with the fact that I was using exogenous Estrogen during this experiment with the Nandrolone. Despite androgens driving aggression and drive, libido and erection quality is largely dictated by adequate Estrogen levels. With all that being said, DHT (with sufficient Estrogen via Testosterone aromatization) is blatantly better for sexual support than Nandrolone, and testosterone itself, even if you completely inhibited 5α-reductase and nuked DHT, still provides better libido and erection quality than Nandrolone does at equivalent "therapeutic" doses for the majority of people. My Blood Work Results On A Deca Only Cycle For HRT I don't like taking shots in the dark when it comes to something that I see potential in. There is a lot of theory thrown back and forth in the community on Deca only cycles, and I needed to see for myself how Nandrolone in conjunction with exogenous Estradiol would impact my personal blood work. I wanted to check markers of oxidative stress, inflammation, kidney function, Aldosterone, Prolactin, hormone levels via sensitive assay testing, and an array of other health markers that are often debated about but very infrequently actually tested for to reinforce statements made. Expectedly, high dose Deca only cycle blasts will almost always result in low HDL levels, subpar Estradiol levels, and an array of other out of range values that are less common and are more individual dependent. To date I have yet to see someone get their blood work checked with exogenous Estradiol being used in conjunction with Nandrolone at a "therapeutic" dose. This is what I wanted to evaluate. Complete Blood Count with Differential/Platelets I was actually expecting far worse from my blood test results. At a "therapeutic" dose, it doesn't seem like my hematology was negatively affected at all. Comprehensive Metabolic Panel In my metabolic panel, nothing was really off to the point that would cause concern. My BUN being high is likely just the result of being muscular and having a high protein diet. Lipid Panel Going into the lipid panel, we can see the number one most common blood test result among steroid users. My HDL is low. LDL is also borderline high, but not overly concerning when I can see that my Triglycerides are pretty low. The reason why my HDL was too low was that my Estrogen levels were too low. Again, this just reinforces the fact that Nandrolone does not sufficiently aromatize into Estrogen. I will get into my Estrogen level and why it was still too low even with Estrogel administration later once we get to that part of the blood test results, but my HDL could have been in range if my Estrogen level was in check. If I didn't use the Estrogel my HDL likely would have been in the single digits. I know I can get my HDL into the reference range if my estradiol levels were doubled, which I have the leeway to do. Iron And Total Iron Binding Capacity Getting into Iron and TIBC we can see that everything looks pretty normal here. Total Testosterone And Free Testosterone Expectedly, by assessing my Total Testosterone level via liquid chromatography with tandem mass spectrometry (LC/MS-MS) and my Free Testosterone level via equilibrium ultrafiltration, we can see that my Testosterone levels were crashed. Both the total and the free were lower than a healthy female. This is what you should see in your blood work if you’re on just Nandrolone. The only Testosterone being produced in my body was indirectly via the trace amounts of androgens produced in my adrenal cortex, which is why the value wasn't completely bottomed out at 0. I've mentioned many times the importance of getting high sensitivity testing done for hormone levels and how Nandrolone will register as Testosterone in primitive garbage blood tests. This is another great example of this. In addition to high sensitivity testing, I had the same blood tested using electrochemiluminescence immunoassay (ECLIA) for my Total Testosterone level, and direct analog enzyme immunoassay (EIA) for my Free Testosterone level. These were the test results using the exact same blood sample with the terrible default assays that doctors will use to determine how to treat you, and that labs will give you in the majority of your blood work panels. According to ECLIA and EIA, I have a normal Total Testosterone and Free Testosterone level. Hilarious. This just one example of why getting accurate hormone testing is critical. My Testosterone levels are actually in the gutter, but the stupid primitive tests that doctors and labs give out as defaults for people is so f*cking stupid that it can't even tell the difference between Testosterone and 19-nortestosterone in my blood. Renin Activity and Aldosterone My renin activity and Aldosterone appeared to be normal. This is one of the main things I wanted to check because there's a lot of speculation around the effect Nandrolone is going to have on Aldosterone levels. When it comes to the Deca only cycle, there's something going on that throws off homeostatic mechanisms that regulate blood pressure that does not appear to be Estrogen related or Aldosterone related. At least based on my blood work, my Aldosterone was definitely not at a level that could imply any kind of negative effect on blood pressure. My Aldosterone level was low if anything. Granted, some markers in the serum can be relatively worthless when compared to actual tissue concentrations, but at least based on my blood work, Aldosterone does not appear to be the culprit. The first thing many jump to when explaining blood pressure regulation is the effect Nandrolone supposedly has on spiking Aldosterone through the roof, but it just doesn't appear to be the case in my experience as you can see yourself here. Vitamin B12 and Folate My B12 and Folate levels were normal. Pregnenolone Pregnenolone appeared to be normal and within the reference range for men which is notable, as many assume that Nandrolone will shut down the production of precursor steroids. That does not appear to be the case either. I assumed precursor hormone levels like Pregnenolone would be less affected than many seem to think as most circulating Pregnenolone is derived from the adrenal cortex. Dihydrotestosterone (DHT) Expectedly, my DHT was very low. This is because I have almost no Testosterone being produced to 5α-reduce into DHT. If my Testosterone is low, my DHT will be low as well. DHT Backdoor Pathway Contrary to popular belief, there is a backdoor pathway via Pregnenolone that can create DHT as well, which contributes to the chunk of DHT I have in my blood. Hemoglobin A1c Hemoglobin A1c appeared to be normal at 5.1%. Thyroxine (T4) My Free T4 was 1.28 ng/dL, which is acceptable. DHEA-Sulfate My DHEA was in range and actually on the high end of normal. Being on exogenous Nandrolone or Testosterone does not shut down DHEA production. Cortisol Cortisol was "normal" apparently, although it looks a bit high to me. I believe this result was mostly sleep hygiene related rather than entirely Nandrolone related. Thyroid Stimulating Hormone (TSH) My TSH is too high. I've never had a TSH this high before. I have had a TSH in the 2's before, this isn't the first time, but never this high. However, based on my resting heart rate and my morning waking temperature and my mid-day temperature, my metabolic rate seems to be the same as it usually is on TRT, and I have had no standout hypothyroidism symptoms. Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) Expectedly, LH and FSH were undetectable. Prolactin My Prolactin was on the low end of normal. This was another interesting health marker to see on Nandrolone, as many will often jump to assuming that Nandrolone spikes Prolactin levels through the roof. That does not appear to be the case though. Prostate-Apecific Antigen (PSA) My PSA level was normal, and did not change from my previous blood work on Testosterone for TRT. D-Dimer My D-Dimer was normal. A friend of mine had a very high D-Dimer level on a Deca only cycle and he wanted me to check mine to see if there was a pattern. It looks like the elevated D-Dimer was case-specific for him and was probably caused by something completely unrelated, as my D-Dimer is normal. C-Reactive Protein C-Reactive Protein is one of the primary markers we have for assessing inflammation in the body. A C-Reactive Protein level of 0.34 mg/L is not overly concerning, although I would like to see it below 0.3 mg/L. I had undetectable C-Reactive Protein levels in the past on TRT, and on Nandrolone it jumped up to 0.34, which is notable. Estradiol, Sensitive My Estradiol (E2) level determined via LC/MS-MS was only 15.4 pg/mL, despite administering 2.5 grams of Estrogel per day. This was disappointing, as I would have liked to see my E2 at least around 30 pg/mL based on the amount of Estrogel I was applying daily. Evidently, my inner thigh was not absorbing the Estrogel very well. This is one of the recommended areas of application, but my results were not even close to in line with the average blood levels found in the Estrogel pharmacokinetics studies. With daily administration of 2.5 g or 5 g Estrogel (corresponding to 1.5 mg or 3 mg estradiol, respectively), mean serum estradiol concentrations of approximately 80 pg/ml (294 pmol/L) and 150 pg/ml (551 pmol/L), respectively, are maintained. Administration of Estrogel also results in increased serum estrone concentrations, producing a physiological estradiol/estrone ratio of approximately one. Therefore, serum concentrations of both estradiol and estrone and the serum estradiol/estrone ratio provided by ESTROGEL® are consistent with physiological levels observed during the follicular phase of the normal menstrual cycle. My inner thigh isn't very hairy at all as I manscape fairly regularly, so I expected at least a 40 pg/mL E2 based on the amount of Estrogel I was applying. I was overly generous with my dose based on the off chance that I would encounter an absorption issue, and my E2 was still way below where I expected it to be. Based on the pharmacokinetics outlined by Merck, 80 pg/mL is the average E2 level for someone applying 2.5 grams of Estrogel per day. There's no way I could have predicted that I would have an absorption issue so problematic that it would result in five times lower absorption than the average. If my E2 was closer to 30 pg/mL, I expect that my HDL would have been pushed into the reference range, and all Estradiol driven physiologic functions likely would have been more optimized. To me, this just reinforced further that Nandrolone is a subpar source of Estradiol as I was using a high dose of transdermal E2 and still could barely reach a satisfactory E2 level. To increase my E2 levels for similar future experiments I will either have to find a better application area, add some DMSO to my Estrogel to increase absorption, or consider Estradiol injections instead. Homocysteine My Homocysteine level was higher than I would like. Normally my Homocysteine is closer to 8-8.5 umol/L. Earlier in the year when I did a shorter Nandrolone experiment for a month using 200 mg per week (double the dose I used for this experiment) I had a Homocysteine level around 8.5, so I doubt this spike was Nandrolone related. This is one of the main markers I always have my eye on because I am homozygous for the C667T polymorphism. Gamma-Glutamyl Transferase (GGT) My GGT looked good. I was worried that this would be cranked through the roof as it is a marker of oxidative stress. Magnesium My magnesium level looked okay. Copper and Zinc My zinc level looked okay. My copper level may be a bit low, which I am now addressing by eating an ounce of beef liver every day. Progesterone My Progesterone was normal, which is notable as it is another precursor hormone that many assume drops to zero when exogenous anabolic steroids are present in the body. Insulin My insulin level was good. Estrone Expectedly, my Estrone was a bit high. This can be a major problem with exogenous Estradiol and Nandrolone unfortunately. Estrone Level Increase From Exogenous Estradiol The ratio of Estrone-to-Estradiol is skewed with massive elevations in Estrone with oral Estrogen administration. Fortunately, this unhealthy ratio can be avoided for the most part with transdermal Estradiol administration. High levels of serum Estrone sulfate (E1S) were found after long-term oral estrogen treatment of commonly prescribed dosages, whereas there was a small increase in E1S levels after transdermal Estradiol (E2) therapy. The mean maximum E1S levels were more than 20-fold higher with oral estradiol (E2) when compared with the 0.05 mg/day transdermal estradiol patch. This is consistent with the 20-fold higher dose of E2 when compared with the transdermal dose [R]. Estrone Level Increase From Nandrolone Nandrolone also significantly elevates concentrations of Estrone in plasma [R]. During a pilot study evaluating the possible beneficial effect of Nandrolone Decanoate (ND) on bone metabolism in patients with rheumatoid arthritis there was a significant increase in the serum levels of Estrone [R]. Despite the fact that Estrone can convert to Estradiol, we can clearly see that the amount this actually happens in the body is minimal based on the consistently skewed ratios of androgens to Estradiol in the blood test results of Deca only users (or Nandrolone in general). Ferritin My Ferritin level is too low. This is likely the result of phlebotomizing too frequently in 2019. Estriol My Estriol level was undetectable, which was expected. Triiodothyronine (T3) My Free T3 level was 2.7 pg/mL. It's not low enough for me to be overly concerned, however, it is suboptimal and should be in the low 3's at least. This is something I will need to address moving forward. With that being said, I like to look at my resting heart rate as well as my body temperature for a more accurate assessment of my metabolism, and both are where I want them to be. My waking temperature has consistently been 98 degrees Fahrenheit, and my midday temperature has consistently been 98.6 degrees Fahrenheit. Sex Hormone-Binding Globulin Expectedly, my sex hormone-binding globulin (SHBG) was low. While this isn't as relevant for a Nandrolone only user as Nandrolone has a very low affinity for SHBG, this is a value I would still like to see in the reference range, especially if I was on TRT. If I had the Estradiol level I was shooting for, I'm confident that my SHBG would have been in the reference range. My Overall Experience On Nandrolone And Exogenous Estrogen For HRT I was expecting to see a bunch of red flags in my blood work, but nothing really stood out as a major concern to me except for the spike in systolic blood pressure, and the high Estrone level. A before and after echocardiogram and calcium scoring would have been nice to see, but unfortunately I can only afford to do so much in these experiments, and the blood work was expensive enough as is. I felt good throughout the entire experiment, I maintained my physique, my libido and penis were functional, and my blood work looked pretty good considering that each issue was something more so related to my Estradiol administration than the Nandrolone itself. Estrone being out of range is a concern, as I would need to use even more exogenous Estradiol to achieve what I would consider a more therapeutic E2 level, which would likely push my Estrone up even higher. The difficulty in controlling the blood pressure spike is also a huge concern and could be a deal breaker. If I gave this experiment more time, it is entirely possible that certain things would have become problematic that appeared to be fine during my three month assessment, like my libido or sense of well-being. It is also possible that despite maintaining a healthy Estrogen level, the same neurological and cardiovascular issues we see in a significant amount of the Nandrolone data could still accumulate over time. In addition, healthy looking serum levels of Estradiol may not necessarily reflect adequate localized Estrogen receptor activation in each tissue. With Testosterone, there is a regulated amount of aromatization occurring in each tissue to satisfy however much Estrogen receptor (ER) activation we need. In the context of Deca only cycles, or Nandrolone monotherapy, there's nothing else I can refer to other than serum levels, my libido, sense of well-being, other cardiovascular health markers, etc. In other words, just because you feel good and your Estrogen levels look good on paper, that doesn't mean that an exogenously administered source of Estrogen is providing the same therapeutic ER activation in all tissues like it would if it were regulated via aromatase. With that being said, you could also argue the opposite as adequate receptor activation via exogenous hormone therapy is essentially all HRT boils down to to begin with in the context of any hormone. More than 95% of our endogenous Testosterone is produced in the testes. Testosterone is supplied to target tissues in the blood, just like most other hormones in the body. If you inject exogenous Testosterone, it then goes into the blood and is supplied to target tissues. If you inject anything it goes into the blood and then is carried to the areas that it is needed. Estrogen replacement has been deemed satisfactory for fulfilling the same functions as endogenously produced Estrogen in women for years, and synthetic Estrogen analogs are handed out like candy to millions of young girls (including teenagers). Is it healthy? Estrogen analogs like Ethinyl Estradiol probably aren't ideal for regulating Estrogen dependent functions, and they definitely aren't ideal for developing women who haven't fully matured. However, there is tons of data to support the fact that exogenous Estradiol is well-tolerated, has a strong safety profile, and can still fulfill physiologic functions sufficiently. In an ideal world, this would be a regulated process in the body in each tissue (aromatization). My experiments do not necessarily reflect what I believe are best practice with these hormones, which should be noted. This was an experiment, and not something that I would recommend someone else do. Using an exogenous progestogen with estrogel certainly isn't what I would consider an optimal HRT protocol, or what is indicative of an ideal means of providing androgenic and estrogenic support in tissues. With that being said, I don't see a better way to go about utilizing Nandrolone on its own for HRT. Should it even be considered as an HRT alternative though? That's the question, and I believe it is largely going to be individual dependent, with a significant amount of users having poor outcomes in one aspect or another. I do believe there are a minority of individuals who are very prone to androgenic and/or estrogenic side effects from exogenous Testosterone use that may benefit from exploring Nandrolone though, and it should not be discarded as a potentially viable alternative simply because it is not the primary bioidentical hormone that men produce.

Testosterone Replacement Therapy is gaining popularity with many advocates and detractors. Lucas and Brion explore the evolutionary basis for testosterone and how that can inform your choice on whether to get on TRT Notes: Testosterone prescribing in the United States, 2002-2016: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396809/ Danish Study on Lowering T levels: https://academic.oup.com/jcem/article/92/12/4696/2597312#52560365 The He Hormone, 2000 New York Times: https://www.nytimes.com/2000/04/02/magazine/the-he-hormone.html Testicle Shrinkage: https://www.thebodywellusa.com/will-taking-testosterone-make-testicles-shrink/ Testosterone Therapy and anabolic steroids: https://thinksteroids.com/steroid-profiles/testosterone/ TRT shuts down production of Pregnenolone and other upstream metabolites: https://www.sciencedirect.com/science/article/pii/0022473185902572?via%3Dihub Supplementing Pregnenolone: https://www.testosteronewisdom.com/pregnenolone-what-you-need-to-know-about-this-precursor-hormone/ Forum thread on suppression: https://www.excelmale.com/forum/threads/anabolic-steroids-and-trt-decrease-shbg-dhea-pregnenolone-and-progesterone-in-men.3990/ T Trials showing Plaque Build Up: https://www.npr.org/sections/health-shots/2017/02/21/515456194/does-testosterone-improve-older-mens-health-it-depends Evolutionary Psychology Wiki: https://en.wikipedia.org/wiki/Evolutionary_psychology More Boy Children After War: https://www.popsci.com/scitech/article/2008-12/why-does-war-breed-more-boys/ Ghengis Khan’s 16 Million Children: https://www.thevintagenews.com/2018/06/09/genghis-khan/ NY Times Is There Anything Good about Men: https://tierneylab.blogs.nytimes.com/2007/08/20/is-there-anything-good-about-men-and-other-tricky-questions/ Low Free Testosterone Predicts Mortality from Cardiovascular Disease: https://academic.oup.com/jcem/article/97/1/179/2833341 Benefits and Risks of TRT: https://www.excelmale.com/trt-benefits-vs-risks/ The Testosterone Scam the Kills Healthy Men: https://www.healthscamsexposed.com/2014/03/the-testosterone-scam-that-kills-healthy-men/ Testosterone linked to shorter male lifespan: https://www.news.com.au/lifestyle/health/testosterone-linked-to-shorter-male-lifespan/news-story/539c29145e7b98692c176e182ee4f777 Testosterone Levels Drop after having kids: https://www.medicalnewstoday.com/articles/234266.php#1 Low Testosterone and Suicide: https://www.ncbi.nlm.nih.gov/pubmed/23893672 Lower Testosterone causing suicide?: https://www.1st-man.com/low-testosterone-male-suicide/ Silent Epidemic of Male Suicide: https://www.bcmj.org/articles/silent-epidemic-male-suicide Music by Jenny Jahlee from Live at KBOO

Let's face it: cortisol gets a bad rap these days. "I have high cortisol", "I have low cortisol", "My cortisol it out-of-whack". You've no doubt heard this all before or said it yourself. So in an effort to decode cortisol once and for all, I decided to feature a wildly popular previous guest of mine - the guy who personally helps me and my wife manage our own hormones and has helped countless listeners of mine with their own anti-aging and natural hormone management protocols. His name is Dr. Craig Koniver. Craig was a guest on the episode "" He has been practicing Performance Medicine for over 18 years and is the founder of Koniver Wellness in Charleston, South Carolina. Not satisfied with the disease-based model of modern medicine, Dr. Koniver seeks to help his clients optimize their health and performance through time-tested, nutrient and science-driven protocols that are the cutting-edge of medicine. He is the founder and creator of the patent-pending FastVitaminIV® as well as re-engineering the NAD+ IV protocols, now called Brain Refuel™. Dr. Koniver’s client list includes Navy SEALs, NFL players, PGA golfers, Hall of Fame NHL players, world-class professional athletes, Fortune 100 Executives, well-known celebrities and TV personalities. In addition, Dr. Koniver offers a comprehensive training program of the Koniver Wellness Model to physician practices across the country. In this episode, you'll discover: -Cortisol 101...5:32 Hormone secreted by adrenal glands Not enough attention is given to cortisol in the medical field "Stress hormone" -- fight or flight response It is secreted in response to any real or perceived threat or stressor We're hard-wired to have high cortisol in the am, and low in the evening Rhythm vs. volume is key Acute hormone; ex. being chased by a lion Turns off pain recognition Anti-inflammatory Catabolic hormone -- wear and tear We've changed cortisol from an acute to a chronic hormone Key takeaway: try to find meaningful ways to live w/ the sun's rhythm Lowest levels are at around 10 pm; allows anabolic hormones testosterone, growth hormone, and melatonin to elevate Most critical hours of sleep are 10 pm - 2 am It takes melatonin 12 hours to reset Later (or no) sun exposure means melatonin levels peak later, leading to loss of sleep quality -How cortisol is secreted...13:37 Perceived stressors (most often subtle in modern times) Primitive part of the mid-brain, above the spinal cord Reticular Activating System (RAS) triggers release of cortisol Signal sent to locus ceruleus (one of the most connected parts of the brain) Signal sent to hypothalamus...to pituitary, then to adrenal glands Norepinephrine and cortisol are "partners in crime"; released along w/ cortisol Pituitary responsible for all signaling molecules We stop releasing cortisol, and have surplus of norepinephrine We release an average of 35 g of cortisol per day Irregular sleep patterns (night shift workers) lead to chronic health problems later in life -How cortisol imbalances affect our lives...20:12 Our brains cannot differentiate between perceived and real stressors Visualizing a success (or a failure) will trigger cortisol secretion "I can't wait to wear that out fit" is much more effective than "I'm way too big..." RAS helps distinguish background and foreground in our world Buy a red truck, all of a sudden you see a bunch of red trucks on the roads What you put your attention is what you're going to get in your life -How cortisol gets disrupted...25:40 Humans are "super-adaptors"; we can tolerate stressors over a long period of time Modern tech can disconnect us from the sun, circadian rhythm and cortisol flow We release cortisol at night when we look at TV, phones, etc. at night We tolerate stressors for years and decades, but it eventually catches up with us It will eventually blunt the anabolic hormones (testosterone, growth hormone, melatonin) We lose sleep quality, take longer to heal injuries, workouts are more challenging, etc. Gold standard to test adrenal function: salivary cortisol test Salivary is far less stressful than a blood draw (hence more accurate results) We rely on stimulants such as coffee and prescription drugs, rather than address the issue of disrupted cortisol flow -Why cortisol is such a hot topic in modern society...37:40 Acute stressor triggers cortisol Over time, cortisol has become a chronic hormone, rather than an acute hormone We'll never be chased by a lion in the jungle We trigger cortisol response w/ everyday stressors Chipping away at cortisol release over time We can't keep up w/ cortisol demands; lose cortisol reserve Major stressor (loss of job, death in the family, etc.) causes a breakdown when cortisol levels have been chronically disrupted Cancer, autoimmune disease, etc. occur with this breakdown Many fear cancer, other serious illnesses Best way to prevent disease: take care of cortisol levels Be aware of indicators of low cortisol levels: poor sleep, longer than usual recovery times, etc. -The key element regarding cortisol missed by conventional medicine practice...43:13 Adrenal fatigue and insufficiency doesn't exist in conventional medicine Two extremes in conventional medicine: Cushings disease, and Addisons disease Cushings: too much cortisol secretion Addisons: not enough cortisol is produced There's a gray area; it's not simply black and white As cortisol levels are disrupted, norepinephrine levels increase Increased heart rate Increased blood pressure This feels like anxiety Consider visiting a doctor knowledgeable in this as you may have lost control of the cortisol buffer Study in the Netherlands on men over 50 who ran marathons vs. men who didn't run marathons Men who ran marathons suffered more heart attacks (due to overtraining) Positive exercise can still be a stressor, releasing cortisol Recovery is key to being an elite athlete -How cortisol interacts with other hormones in the body...49:30 Hormones are like kids w/ differing personalities Cortisol is the neighborhood bully High insulin levels and cortisol lead to weight gain (cut carbs in the morning) Abnormal cortisol modulation affects thyroid levels deleteriously Be aware of your adrenal status if you're on thyroid hormone replacement An imbalance of cortisol and testosterone inhibits muscle production Growth hormone depletion leads to brain fog, weight gain, etc. -How to effectively modulate cortisol...56:52 Tests: Blood in the morning Salivary cortisol test anytime Adrenal glands is like a factory producing hormones: cortisol is the goal, but we need to make the other hormones Cortisol imbalances lead to depletion of other hormones Pregnenolone is made from cholesterol; low cholesterol levels affects cortisol production Number 1 risk factor for cancer for men is low testosterone; cortisol will help optimize health Having a cortisol reserve enables us to handle and tolerate stress, thus preventing cancer, autoimmune disease Behaviors to normalize cortisol levels (deliberate contemplative exercise) Meditation, prayer, reading Activate parasympathetic system, turn off sympathetic system Meditation is not the only means of managing stress Adaptogenic herbs: Licorice root (delays conversion of cortisol to cortisone) Holy basil (sense of the divine in one's world) Cordyceps powder (in coffee, shakes) Rhodiola Schisandra berry Critical nutrients: Vitamin A Vitamin C Vitamin B5 Intravenous NAD+ Peptides: Hexarelin Epithalon Ipamorelin GHRP 6 and GHRP 2 Intranasal and intravenous stem cells Hydrocortisone replacement (don't surpass 35 mg per day) Phosphatidylserine Ashwagandha CBD -Closing thoughts...1:14:42 Good correlation between HRV and cortisol; collect morning and evening times Cortisol helps be your best cognitively If you're feeling tired, stressed and anxious, check your cortisol levels -And much more... Resources from this episode: – -30-minute patient phone call with Dr. Koniver to review health goals. At end of the call, Dr. Koniver will outline a strategic game plan for optimizing patient health and performance.  -1-hour physician practitioner phone call with Dr. Koniver to discuss how to implement Performance Medicine into your practice. At end of the call, Dr. Koniver will outline specific steps to start.  -4 Day NAD IV Therapy (Brain Refuel Program). Patient flies to Dr. Koniver’s office in Charleston, South Carolina to receive the loading dose.  -Umbilical Cord Stem Cell Program. 3 days of NAD IV Therapy followed by an umbilical cord stem cell infusion. Includes injectable peptides as well as select nutrients to aid in the absorption of stem cells.  Episode sponsors: -Boundless: -: The Challenge starts January 6th, it's completely FREE to join, and when you do you'll get a bunch of exclusive content including access to a Q&A by yours truly answering all your burning fasting questions. To join just go to getkion.com/fasting -: After using the Joovv for close to 2 years, it's the only light therapy device I'd ever recommend. Give it a try: you won't be disappointed. Order using and receive a month's supply of Kion Berry Aminos absolutely free. -: I’ve been using Four Sigmatic products for awhile now and I’m impressed by the efficacies of their mushroom products. I use them. I like them. I support the mission! Receive 15% off your Four Sigmatic purchase when you use discount code: BENGREENFIELD Got a question for me or Craig related to cortisol, or anything else we talked about in today's show? Leave a comment below, and one of us will reply!

Il pregnenolone è un ormone steroideo coinvolto nella biosintesi di progesterone, mineralcorticoidi, glucocorticoidi, androgeni ed estrogeni. In centinaia di Paesi al mondo, inclusi Stati Uniti e Paesi Europei, è liberamente commercializzato quale prodotto alimentare ( food supplement ), ma anche per ricerca o come materia prima nonché quale prodotto cosmetico.

How you can best support yourself over the holidays? The holiday season can be a stressful and sometimes overwhelming time for a lot of people. In this Q&A episode, I share some great strategies on how you can best support yourself while dealing with the holidays.  You can find all the info and links about this episode at https://holisticwellness.ca/episode87 Topics Discussed in this Episode: What causes hypothalamic amenorrhea and what you can do about it Strategies to support yourself when you’re on the pill or getting off the pill Tips to stop acid reflux and constipation Healthy holiday survival tips   Key Takeaways: Functional hypothalamic amenorrhea is a condition characterized by the absence of a menstrual period for three or four months in a woman of reproductive age. What’s happening here is that there is a breakdown in communication between the hypothalamus, your pituitary glands, and your ovaries. The pill is one of the biggest causes of amenorrhea. This poses a problem for many of the women who have been on the pill for many years because their ovaries may have become resistant to resuming ovulation. Your hormones need fat to function. Pregnenolone is the mother hormone and it’s synthesized from cholesterol. Acid reflux is typically due to too little acid production, which is so important for digestive health. Stress and fatigue are two of the biggest immune system offenders.   Action Steps: Simple strategies to support yourself when you’re having amenorrhea: Start incorporating more protein and fat into your diet. Supplement with B vitamins. Work on healing and supporting your gut. Exercise. Re-balancing tips when you have acid reflux: Avoid trigger foods like coffee, chocolate, alcohol, tomatoes, pepper, spicy foods, and citrus foods.  Don’t eat anything 2 to 3 hours before bed. Take apple cider vinegar.  Incorporate deglycyrrhizinated licorice Support your body over the holidays: Make sure you’re getting in your vitamin D. Supplement with zinc. Take a daily probiotic. If you are prone to getting cold sores, take 1,000 to 2,000 mg of L-lysine. Take immune supportive mushrooms. Have things in moderation. Have a hand sanitizer on hand. Rest more and stress less. Do the movement that you love and that feels good in your body. Make sure you stay hydrated.   Samantha said: “If you find that this is the time of year where you do typically get sick… recovery can take longer because you might be eating too much sugar, drinking too much caffeine, maybe overdoing it on the alcohol -- all things that suppress the immune system.” “There’s nothing wrong with going out and enjoying yourself but have things in moderation. You don’t need to overdo it.”   Thanks for listening!   Important Announcements: Join our FREE 5 Day Sugar Detox Challenge!   The Metabolic Reset is currently open for registration and it’s currently on SALE! From January 13, 2020, it’s going to be 8 weeks of amazingness!   Get your copy of my new book, The 30-Day Hormone Solution.  Order on Amazon in Canada here  Order on Amazon in the US here   Connect with me over on Instagram, @holisticwellnessfoodie. It would also mean so much if you would leave us a rating or a review at any podcast platform that you’re listening to us on.    Links to things I talk about in the show: How to Ditch Hormonal Birth Control eGuide + Cycle Charting Handout & Hormone Questionnaire Save 20% on Skin Essence Products with the coupon code healthy hormones + free shipping on orders of $50 or more in the US and Canada. Skin Essence Canada Site   Skin Essence US Site   doTERRA Oils/Products - Email me if you'd like to set up a call and put together a custom kit at samantha@holisticwellness.ca or you can order through my link here.   Where you can find me: Samantha’s Facebook Samantha’s Instagram Samantha’s Website Samantha’s Twitter Healthy Hormones for Women Podcast Private Community on Facebook   How you can work with me: 6-Week Healthy Hormones for Women Intensive - Get 60% when you enroll today! Healing & Dealing with Hashi’s

Talk to a Dr. Berg Keto Consultant today and get the help you need on your journey (free consultation). Call 1-540-299-1557 with your questions about Keto, Intermittent Fasting, or the use of Dr. Berg products. Consultants are available Monday through Friday from 8:30 am to 9 pm EST. Saturday & Sunday 9 am to 5 pm EST. USA Only. Take Dr. Berg's Free Keto Mini-Course! What to DO if you Have Thyroid Problem https://www.youtube.com/watch?v=pm49u... Stress Webinar: https://www.youtube.com/watch?v=ueI10... In this podcast, I'm going to share with you how to boost your pregnenolone for more hormone energy. What is pregnenolone? Pregnenolone is a precursor or a main building block to make your sex hormones and stress hormones. These hormones are: • DHEA • Estrogen • Progesterone • Testosterone • Cortisol Pregnenolone is made out of cholesterol. We need cholesterol. It's very important. If you don't have enough pregnenolone from cholesterol: • Your memory suffers • You get tired • You get brain fog • You can't sleep • You lose vitality • You lose libido • Your body fills with inflammation Dr. Eric Berg DC Bio: Dr. Berg, 51 years of age is a chiropractor who specializes in weight loss through nutritional & natural methods. His private practice is located in Alexandria, Virginia. His clients include senior officials in the U.S. government & the Justice Department, ambassadors, medical doctors, high-level executives of prominent corporations, scientists, engineers, professors, and other clients from all walks of life. He is the author of The 7 Principles of Fat Burning. ABOUT DR. BERG: https://bit.ly/2FwSQQT DR. BERG'S STORY: https://bit.ly/2RwY5GP DR. BERG'S SHOP: https://bit.ly/2RN11yv DR. BERG'S VIDEO BLOG: https://bit.ly/2AZYyHt DR. BERG'S HEALTH COACHING TRAINING: https://bit.ly/2SZlH3o Follow us on FACEBOOK: https://www.messenger.com/t/drericberg TWITTER: https://twitter.com/DrBergDC YOUTUBE: https://www.youtube.com/user/drericberg123 Send a Message to Dr. Berg and his team: https://www.messenger.com/t/drericberg

November, or Brovember as we like to call it, is all about our men's health at SuperFeast. Today we're thrilled to have our good friend Dan Sipple back on the podcast. Dan is absolute gem and wealth of information in his field of natural medicine. In today's chat Mason and Dan discuss the importance of men's hormonal health and outline the diet and lifestyle factors men can embody to keep their hormones primed and rocking.  Dan and Mason break down: The male hormonal cascades. The importance of brain and cognitive health in regards to male fertility. The influence of diet and lifestyle on healthy hormonal function. The two simple pillars of hormone health; Sleep and Breath. Testosterone; the amazing hormone. Detoxification and reproductive health. Genetic testing. The connection between abnormally high iron (ferritin) and male infertility.  The role zinc plays in the conversion of androgens. The damaging effects of chronic inflammation in regards to hormonal health. Naked sunbathing and vitamin D3. The herbs that stimulate and antagonise androgens.   Who is Dan Sipple? Dan is a also known as The Functional Naturopath who uses cutting-edge evidence-based medicine. Experienced in modalities such as herbal nutritional medicine, with a strong focus on environmental health and longevity, Dan has a wealth of knowledge in root-dysfunction health.   Resources: Dan Instagram Dan Email Benny Fergusion - The Movement Monk The Dutch Test - Carrie Jones Podcast with Tahnee The Wildcrafting Brewer Book by Pascal Baudar SuperFeast Deer Antler  SuperFeast Ashwagandha SuperFeast Eucommia Bark SuperFeast Cordyceps   Q: How Can I Support The SuperFeast Podcast?   A: Tell all your friends and family and share online! We’d also love it if you could subscribe and review this podcast on iTunes. Or  check us out on Stitcher :)! Plus  we're on Spotify!   Check Out The Transcript Here:   Mason:  Hello everybody, we're welcoming back our good mate Dan, Dan Sipple, functional naturopath, how are you going man?   Dan Sipple:  Mate, I am fantastic today, how about you?   Mason:  Yeah, I'm really good. It's a nice sunny day down there, nice sunny day up here, we'll get into why that's significant and important if you're a man, you're going to be very happy at those points when the sun comes out. Thanks for joining me for Brovember here at SuperFeast focusing especially on this pod, going through some very important aspects and elements for men's health, men's physiology, things that, it's just going to be great. As they say, "They should teach this in schools," because it would actually be useful for us to understand about our hormonal cascades and our physiology going forth.   Dan Sipple:  Absolutely, and it's exciting. It's an exciting time to be alive and loving all the information that is just coming through right now in our amazing little world of natural health and how that can affect hormones and we'll dive obviously deep into all that stuff today I'm sure.   Mason:  Yeah, I think it's great as well. I really like this time of being alive as well, because we've gone through the extreme deconstruction of what's going on with health, and including lifestyle and dietary kind of fads that have been reduced to their parts. Likewise, of course we've learned a lot about the body through a reductionist western model, which can even sometimes cross over into naturopathic thought, but then it's synthesising and emerging, and just a real blossoming time where it's kind of coming together and being able to come into harmony in a lifestyle long term that doesn't make you feel like you as a person, in working on these things, need to reduce aspects of your lifestyle to work on them necessarily.   Mason:  Of course there's going to be areas where we put our focus upon, it's a very important thing for men to be able to do and then the aspect of men to able to have laser-like focus on something we're working on. That's when men can quite often in health scene loose themselves and we see that in many areas of dietary faddiness and going, that focus takes us right down the barrel of dogma or down the barrel of something like the more of the extreme bio-hacking kind of scenes, where we remain compartmentalised in our day, or our supplementation, or our diet.   Mason:  I think now we're seeing that the emergence of us being very aware that we have a foundational personal culture, lifestyle that mingles in with our family and our community and how can we sculpt an integrative lifestyle that's going to lead to these various markers, these various hormonal cascades and processes to be naturally nourished and able to function and regulate themselves, just through us living our lives, right?   Dan Sipple:  Absolutely, and I think people, men and women are just.. It's A time in the human existence where it's like we're feeling it now. People just know that there's something not quite right, and obviously being a naturopath, I'm a little bit biased because I'm seeing a lot of those people, naturally. But I think I read a study a couple of weeks ago that was saying something like men in even the 60s and 70s had just such a higher grade of production across the board of testosterone compared to men now. And it's a scary thought. I think I read in the same study something like by 2035, the rates of infertility in males is just going to absolutely sky rocket should all the factors, which disrupt that sort of cascade continue to be at work.   Mason:  Boys, let's learn how to not become just another statistic, take control of your sovereign health and hopefully end up with nice healthy levels of testosterone. Of course we'll have a little bit of, I guess that will be a little bit of a pillar. Where we go is you take us through the entire hormonal cascade from upstream, right through the middle of the stream, to downstream and then I feel like, you will of course go into this physiologically, but lifestyle wise, how that downstream is then ... We talked a little bit about it if we are a microcosm, in the macrocosm here where, and we have the reflection of nature within us, of course it isn't just upstream to downstream and then you get your results. What's going on downstream is very much going to evaporate and emerge and go right up to the top of the stream and affect our ability that, you know those kingpin aspects of our health.   Mason:  So, with that lets start jumping in. Was it the hormonal cascade in general and just the nature of that and the process of that do you want to take us through primarily?   Dan Sipple:  Yeah, I think it would be good just to do a little refresher on the actual physiological side of it, just to give focus on a bit of a mental picture. And if there's anything the guys take away from this today, and girls, it's that, just not to focus on male hormone production at the area of the downstream like you said, the testes and the adrenals. And to really factor in how important brain health is, and cognitive health, because that organ itself is the master commander, it's commanding that communication down to those organs to say, hey make testosterone mate, make DHEA et cetera.   Dan Sipple:  And that all starts from two hormonal chemicals, I guess you call them. Follicle Stimulating Hormone FSH, and Luteinizing Hormone LH. So they're speaking down to the leydic cells in the testicles to say make hormones, make testosterone and they operate like many hormones do on a bit of a feedback mechanism, a negative feedback mechanism. So for example, if testosterone down at the testicular level is adequate, FSH and LH back off in men and in women respectively with testis and ovaries.   Dan Sipple:  Likewise, if the production is low, those at the higher end in the pituitary LH and FSH will spark up and start screaming down at those organs to say, make more hormones, make more hormones. And there's a lot of things that we'll get into that can disrupt the communication between those two vital organs. So I've got that going on and then in terms of the steroid pathways, that's another kind of area that you weigh into the equation with regards to how cholesterol from the diet then gets transferred down into hormones like Pregnenolone and Progesterone, and across to precursors to testosterone and oestrogen like androstenedion. And again, things can go a little bit haywire during that conversion if there are other factors that play such as things like stress, acute infection, illness, a plethora of things, different herbs as well will affect the destination. Ultimately those signals.   Dan Sipple:  But essentially, we're starting at cholesterol and we're wanting to get down to progesterone in men and females. What can happen as a bit of something in between those two, an interruption if you like, is we call this the pregnenolone steal, and there's still a little bit of controversy around that in our field on whether it's actually a thing. You'll read a lot about that online and whatnot. The theory is that cholesterol starts and if it doesn't reach progesterone, pregnenolone comes in and diverts that signal down to cortisol, which is the stress pathway, and away from testosterone and away from oestrogen and away from DHEA, which for men and females are all the hormones responsible for making you feel strong, resilient, able to recover, confident, et cetera.   Dan Sipple:  With today's level of chronic stress and inflammation, a lot of hormonal panels when we look at them in folks with different stuff going on, will show that they've got a lot of production going down that cortisol pathway. It's being stolen if you like, hence the phrase the pregnenolone steal.   Mason:  And so, let me know whether you want to just go through the full range first to give us an insight, or whether you want to just start diving in there, because that seems like one of those critical physiological points. And when you're talking about stress, we've kind of gone through the stress model before in a podcast, but clinically, was it the pregnenolone steal? Is that what you said?   Dan Sipple:  Yep.   Mason:  So at that point, when you say chronic stress, you're talking about a diet that's going to be causing high amounts of inflammation and you're generally going to talk about a lifestyle that's going to keep you within the variations of a sympathetic nervous system, rather than being able to get into that deep parasympathetic.   Mason:  This is something interesting because clinically we see it a lot of the time and we hear it again and again and again, being banged on about getting out of the stress response and making sure you don't have stress in your lifestyle. But then, of course that's kind of a reductionist view in itself in terms of it's like a light switch and when it's on, you're in sympathetic and you're stressed and you're running away from the tiger. And we are boom, we turn it off and now you just happen to be relaxed.   Mason:  I feel like there's more and more, the conversation in men's health and women's health as well is coming to the various nuances and the personal relationship that you have with the reality of what a parasympathetic state is and what being able to approach the world in a way where you're nervous system isn't running a rye, your amygdala isn't throwing up past fears and memories that are then affecting your HPA axis and therefore taxing your adrenals. There's so many different nuances and because men are so focused and love to hanging on to things especially in processing mentally things, it's like all right, now I need practices that switch it off, turn it off and get me into this static thing that is a parasympathetic system.   Mason:  So, I'm just interested in some of, just clinically of course you're bridging people to try and get some protocols going, where they're maybe meditating, maybe doing something like a yin yoga or generally just coming back to their breath daily in order to really approach life in kind of more a balance between that yin and yang. But have you got any kind of tips or insights in terms of how we're going to deal with that stress without it being a reductionist conversation?   Dan Sipple:  That's a big question, I like it. I'll say first of all, the first two things that I always try and dial in, sleep and breath. Sleep and breath. It's that simple. If you can get a male, take a tradie for example. I see a lot of tradies down here. High pressure, they have to be able to exert authority on the job side, they have to be able to cope in that environment, and the ones that can't, usually leave the trade, from what I hear.   Dan Sipple:  But getting them to dial down from that, that sort of level of activity once the day is over, and just getting them doing this simple stuff like I say, if you can just do one minute, if you can do 60 seconds, where you can take literally eight to 10 breaths only, to get down to that level. That done daily as soon as you get home. So go outside, strip off your clothes, get you bare feet on the grass, sit down, let the sun hit you, have a chamomile tea or something like that, that's just going to take that edge off, probably the worst thing to do, which a lot do, is just go and smash four or five beers, and that's [crosstalk 00:11:30], because they want that [inaudible 00:11:31]. It's understandable, they want to come down. But we'll get into why that's not a great idea down the line.   Dan Sipple:  Breath and sleep, just dialling those two in. And sleep is something that so many people, I know I've banged on about this in the past, but I find people get it right and then they drift away from it and they forget that they got it right, and they slip back into old habits and they become really hyper-focused on the supplements and the weights and the diet and all that, but they forget the sleep. And I'm guilty of it 100%, I put my hand up. It's always something that I'm constantly trying to reel back in. I don't know about you, but it's something that I just find, if it's out of whack, there's no point even trying with the other stuff. That has to be first and foremost.   Mason:  I mean it's an interesting thing because you're right. And men are quite often, and then generally going to be those kinds of people that you give them an inch and they'll take a mile. And so, if you treat sleep and having somewhat of a subtle breath practice or even throughout your day where you can come into noticing your breath and allow that noticing without agenda to be the precursor for your actions, so in that awareness of the breath, you are leaving space for a non-stuck in the mental state, or non-stuck in an over identification with the physical to take place. In that space when you're just observing the breath. You then have an ability to have a noticing of what's going on with the mind and what's going on with the body and therefore there's less division and there's less as you said, that focusing on the thing which the mind tries to do. I'm going to do these weights to heal this problem, I'm going to do this ...   Mason:  So when it comes down to, there is, although that stuff is fun, you're never going to be able to go past the chop wood, carry water practice. Now if you really think about that, rather than it being just another thing, great, I'll take on that practice of chopping wood, carrying water and just doing that mundane for the rest of my life ... I was talking to my acupuncturist about it the other day and he was just like, and I was like, "Yeah man, that chop wood, carry water, I'm really working on it, but it can be really fleeting at times." And he was just like, "Listen mate ..." And my interpretation is we have such a privileged world, where we don't actually have to do the chopping of wood and carrying of water, but we do have to go to work every day, we need to be working on our homes and our cars and things that keep us going so that we can have the wood in the warmth and the material for us to live in this house and the water.   Mason:  Normally we're thing like actually chopping wood and actually getting up and carrying water and bringing that so we have something to drink, but now we're doing it in different ways, but it's the same thing. Keep ourselves warm and sheltered with chopping that wood and ensuring that you always have water to sustain life and cook with and prepare everything that we rely on water to do.   Mason:  That, because those practices are as methodical and slow and Yin in their repetitiveness as they were, they're very dynamic, naturally we need to lean a little bit more into the intentional nature of there are things like chopping wood, carry water, if you think about doing that for the next 40 years, this is what my acupuncturist was talking about, classically trained, worth mentioning, not modern TCM style. Is that, you're doing that for 40 years, of course along the way you are going to have some big pops and big insights and it's going to be moments of enlightenment, which of course the whole nature of chop wood, carry water is to release that enlightenment, otherwise you will be stuck in that place. And then, if you look at the majority of it, it's going to be very mundane, very boring, and very repetitive.   Mason:  But the nature of that is so beautiful in what it's going to do if you're going to accept that, and realize it's not always going to be bells and whistles. All of a sudden, the simple act of chopping wood and carrying water and coming consistently back to the breath and back to your practice daily, if that's one minute or if it's back to that practice of that discipline of screens down, creating that beautiful sleep environment, absolutely prioritizing bedtime, and if I can't prioritise, be able to get to stay up and stay asleep the next morning.   Mason:  We all have kids, a lot of us have kids, a lot of us have hectic jobs and social lives. But that chop wood and carry water, I think at the essence of this men's health message, that needs to be respected and honored, even if you're standing solid in your Yang. If you look at the Yin and Yang symbol, there is always going to be that place where you can stand with the Yin, within the Yang to ensure that, that is there and present so you don't have these hormonal stealings, which are going to lead us, this generation being dramatically lower in testosterone, and basically emasculated, right?   Dan Sipple:  Totally, and that's the thing too. How many males do we know that over train and spend too much time if you like in TCM terms, in the Yang, and just burning that furnace, I've got to lift weights and I've got to smash it and I've got to do this and do that. And I've got to make so much testosterone jacked up, and this and that. And it's like yeah, do all those things and that's cool, but fuck, regenerate man, get that sleep, get that breath dialed in. You have to regenerate, you have to dial in to regenerating, otherwise, let's face it, it's when you sleep that you build your testosterone and your growth hormone.   Mason:  In your blood, right?   Dan Sipple:  Yeah, and your blood.   Mason:  It's in your blood. That's kind of what I think, women are so, women are more sensitive to it because women are way more prone to running low on blood. Women are running on blood. We're running on Qi generally, and so it's a little bit, because we're not bleeding every month, it's a little bit harder for us to become deficient in blood, but it comes up and bites men in the arse, it's a gradual thing, but when you're over-training, over-ejaculation, overworking, in your mind excessively, you can go for so long. But then eventually bit by bit, you're chipping away at that blood and that Jing and ultimately when you look at what's going on hormonally, you're chipping away at the efficacy of these pathways and so you're going to end up in a place where you are deficient and it's not going to be a supplement, and it's not going to be a training session that's going to be able to turn that back on, build that blood back and actually restore the ability of these pathways.   Dan Sipple:  Mm-hmm (affirmative), 100%. And I want to make it clear too to the men listening. I'm not saying don't do all these things, we're not saying don't go and lift weights, and don't try and optimize testosterone, because I still think there's a lot of shame politically around that today, which I really want to see dispel. I hope this doesn't come across the wrong way, but I feel like, especially in naturopathy especially, there's a lot of focus on female hormonal health and it's totally acceptable and it's not even thought of twice for a female to want to optimize her estrogen and her progesterone and regulate her cycle and yadi, yadi, yada.   Dan Sipple:  As soon as a male wants to build up his testosterone, I feel like there's a bit of a stigma there still in some circles.   Mason:  You know who kind of cracks that with Stephen Harrod Buhner. He was totally in those herbal scenes going, "Hang on, we've got this huge apothecary full of phytoestrogenic herbs that are absolutely incredible for women's hormonal health." And we've got really nothing driving androgen, no herbs driving androgen, basically androgenic herbs. And then when he brought pine pollen, and that book on pine pollen that I think he supported or wrote, but he just championed it.   Mason:  Because he's such a gentle man, I feel like it was accepted, and he begun the process. But you are right, if you are taking pine pollen even to an extent ashwagandha, deer antler is probably the biggest one where people associate it with, of course maybe not in this community as much, but very much generalising. But you're right, the stigma is there, you're a boof head for wanting to, "You want to jack up your testosterone do you? Yeah, Good on you." In order to develop Shen, far out. In order to continue to grow our personality, emotionally, spiritually going deep into the ether of ourselves in order to become better humans, better men, you absolutely require that baseline testosterone optimisation.   Mason:  I'm with you, and it also comes down to the way that men approach it. There's no other context rather than, all right, you know we're going to like get, I just want to jack up my testosterone, I don't know how that connects to everything else. The only association with it is to become "more manly" and therefore that has a glass ceiling on its usefulness, right?   Dan Sipple:  Totally, yep. You nailed it, and that's another thing I really want to highlight too in that context is that don't just think of testosterone as my testosterone is up because I'm horny, because I feel like I'm keen and I'm good to go. Na man, bone health, you need to [crosstalk] testosterone, and immune function you need testosterone. Cognitive health, brain health, sleeping well, recovering, all that sort of stuff as well comes into that amazing hormone, which is testosterone.   Dan Sipple:  And I say to a lot of patients too, our physiology and our genetic demands and our DNA is, it sounds really harsh, but it does not give a shit about what's going on today societally. It doesn't care that we've got food problems and government problems and this problem and that problem. It's demands are exactly the same as they were seventy years ago, and you have to serve that. I'm sorry, you have to recognise that, and the sooner you do and start getting things back to simplicity like it's referring to, chopping your wood and your carrying your water. They're metaphors, but the audience, and I know exactly what you mean by that. Stripping things back to that simplicity just so that as a man you are serving your physiology and you're not putting things into your body and putting practices around your environment which affect that.   Mason:  So, just to kind of finish up on that, that stress conversation. I feel like it's a good point. If any guys, they feel like they're really rocking their physical practice in terms of, in that aspect of men's health, whether you feel like it's, whether you're lifting weights or you're running or whether it's MMA or whatever. If you've got that kind of side rocking and you're really loving it, you want to make, then you want to have like a more integrative practice in a way of training and practicing, approaching life from that parasympathetic place so that you can widen your cup, so that cup can hold more of these androgenic hormones and testosterone.   Mason:  My man Benny Ferguson has that really, really great programs, you can get in touch with him to see what might be ideal, but whether it's the tension release programs or in body flexibility or whatever it is, there's some really beautiful practices and you can hopefully find something there for yourself and as well, connect to the breath outside of dogmatic or, not that they're all dogmatic, but sometimes you don't want to enter into another clique. You don't want to go into a different style of yoga, you don't want to go into a different style of soft martial art. You want to just be working on your pure physiology and connecting to your breath and there's many people doing that in a way that's not just based on cues and rules of what it should look like to get good output. Many people are doing that, but Benny happens to be the one that I work with and I think he can be a really great resource for a lot of people, he's a beautiful man.   Mason:  So that stress, I think we've kind of really hit somewhat of a core of that ability to not maintain a life that's not philosophically stressful in the way that you approach it. Is there any other aspects of the pathways you want to go into before you jump into cholesterol? Otherwise, I want to really hear your two sense on it.   Dan Sipple:  Just touching back on that cascade we got kind of from cholesterol to progesterone, if all things are going well, then across to Androstenedione and then again if all things are still going well, across the testosterone ultimately.   Dan Sipple:  An important thing to look at there is, and it gets a little bit tricky, but I'll try and break it down, aromatase, which is an enzyme which influences or encourages the conversion of testosterone down to estradiol or E2 in men and female. And the really neat thing is when you do a DUTCH test by the Precision Analytical Company-   Mason:  That's not [Carrie] is it?   Dan Sipple:  That's Carrie.   Mason:  Dr. Carrie Jones, so that's for men as well, did you say?   Dan Sipple:  Totally, yep.   Mason:  That's cool. That was a great podcast that Tahnee had Dr Jones on. All right, great. We will put that in the show notes, so-   Dan Sipple:  She is a weapon. If anyone hasn't followed her yet on Instagram Dr. Carrie Jones, she's amazing.   Dan Sipple:  There's certain compounds that are going to influence that conversion, but ultimately if you're a man, obviously you want to keep it dialled in at testosterone, you don't want to lose that to a conversion process down to oestrogen, which inflammation, excess body fat, high insulin. So if you're getting too much carbohydrate and refined sugars, you'll influence that. Alcohol is a classic one that's going to encourage testosterone to convert down to oestrogen. And-   Mason:  A man's drink.   Dan Sipple:  That's right, exactly.   Mason:  Beer made with the most oestrogenic herb on the planet-   Dan Sipple:  Can't be-   Mason:  [crosstalk 00:25:47].   Dan Sipple:  What do you mean? That's right. Guys, beer, we have alcohol and we've got hops in there, double whammy, not so good for your testosterone.   Mason:  Yeah, but it's so delicious.   Dan Sipple:  I know.   Mason:  I think that's a nice thing, we'll bring it home in the end. We'll talk about, really, I can't stand having a rule based approach, not allowed this, not allowed that, so it's like ... My gosh, I can't wait until natural androgenic beers starts actually hitting the market. It's going to be the most incredible revelation and this is going to pop it for men that, Hops is literally, I think literally the most oestrogen forming herb that we have on the planet, and the man's drink not only you have like a shit load of beer, you're going to have excessive alcohol in the system, which is going to help, it's going to ... Is it an antagonist for aromatase?   Dan Sipple:  It encourages aromatase. So aromatase, you want to inhibit it ideally. So I think like zinc, grape seed extracts-   Mason:  Nettle root.   Dan Sipple:  Nettle, you've got damiana, [inaudible] and those sort of things, will inhibit that conversion, that enzyme. But yeah, androgenic beer, man.   Mason:  Yeah, pine pollen beer with no Hops, no grain, it's going to be the best thing. Everyone can go and get, and then start making their own with Pascal [Boudet 00:27:12], I think I've got my French-   Dan Sipple:  Have you done it before? Have you experimented with-   Mason:  We don't have that kind of crazy time, we try every now and then, [Tahnee] and I try to, we're kind of working our way back into being in the kitchen where we can get really fermenty again. We've gone and done the workshop with Pascal, where we went and foraged everything we made. We made a beer with few different types of sages and reishi's and fermented limes and a shit load of mugwort in order to bring out that bitterness. I've had a lot of natural beers and it's just like, it's watery, it doesn't have that oomph and punch that a beer normally does. But Pascal, I think he's the wild brewer, anyway ...   Mason:  Pascal is, we'll put the notes for the book down there. He's got a wild crafting brewer, or something like that, and he can teach you how to make these natural beers and you can just go and put pine pollen in there. You can either use SuperFeast like Deer Antler or we'll go to China Town and get deer antler slices and throw that in there to the fermentation process. Then you're kind of working with something, and you're working with an androgenic beer, but the way he makes them, he gets the flavour profile and he gets that meatiness that you need to hit the spot.   Mason:  So we started with aromatase and we went off to beer, but that's natural.   Dan Sipple:  That's all good. And then additionally into aromatase, there's another enzyme called 5-alpha reductase, which can also push testosterone down to its more potent form, 5-alpha DHT, which is also known as dihydrotestosterone. I think there's still a little bit of debate on whether you want to limit that conversion or whether no, You actually do want some healthy degree of DHT, which is the more potent androgen form of testosterone. I think there was a bit of a stigma because of the association and literature around BPH, Benign Prostatic Hyperplasia, and that being associated so they say, with higher DHT, dihydrotestosterone.   Dan Sipple:  We'll get into further, but that's essentially what I wanted to kind of just bring to light, the cholesterol conversion, and then once you arrive at testosterone, if all is going well down that cascade and that chain, keeping it there, rather than letting it go to those other hormones which we don't really want too much of as males.   Mason:  In terms of like the estriol or the estradiol.   Dan Sipple:  Yeah.   Mason:  Okay.   Dan Sipple:  And cortisol too. Yeah.   Mason:  Where does the cortisol come into it? Is that in the pregnenolone steal?   Dan Sipple:  That's right, so that's backup the chain. So that's before it gone across to testosterone, so it starts at cholesterol. You want it to get down to progesterone and then skate across from progesterone to the androgen pathways, but between cholesterol and progesterone, pregnenolone is kind of in the middle there and that can divert it if you like, down to the stress pathway...cortisol.   Mason:  Okay, cool. Well, let's go up and let's start breaking it down a little bit. So cholesterol, I think by now most people should know, but if you don't know, is the primary ingredient for the creation of hormones. Backbone of creation of hormones, so that's why you see a lot of people getting very passionate about having the inclusion of cholesterol in saturated fats in the diet, especially back probably a decade ago. It was like a massive kickback on a wider scale from those low fat diets and the 80-10-10 diets. 80% carbohydrates and sugars, 10% fats, 10% protein.   Mason:  And even in a lot of vegan and raw circles, as that kind of got to it's height, you saw a lot of endocrine disruption occurring and it kind of, a lot of it came down to the fact that no one actually had the backbone for the creation of hormones and then naturally that affected the nervous system as well. So, now it seems more of a normal conversation and there isn't that, even on a cultural level in Australia at least, there's not as much of championing of low fat diet.   Dan Sipple:  There was.   Mason:  Yeah, I don't even know whether the Healthy Heart Tick, I don't know whether that institution of dieticians is ever going to budge. But I don't know where you're at with your knowledge, [crosstalk 00:31:26].   Dan Sipple:  I don't even look at what they're doing anymore Mason, to be totally honest with you. It sometimes comes up in a conversation with a dietician or around the traps, but I try and shy away to be totally honest.   Mason:  But this study from Sanatorium told me-   Dan Sipple:  You've got it. We digress.   Mason:  All right, so what have you got to say on the cholesterol front?   Dan Sipple:  Well look, I see a lot of people on plant based diets and a lot of people on the flip side, that are doing close to carnivore diets. So I see them both. I think it's important to highlight that the body is a machine and a weapon and it will do its best to serve you no matter what diet you're doing for a time. In the plant based realms, I can hear people going, "But I get plenty of cholesterol, I have coconut oil for this, and I put coconut oil on that, and this and that."   Dan Sipple:  There's going to be a time where that supply, that kind of constitution and life force will start to dry up, eventually, that's just inevitable. And that can be argued til the cows come home, but I see it, I see it, I see it. And I've felt it before too, where you lean more towards those plant based diets and then you feel what it's like when you return back to a diet where you're getting lots of different saturated fats and mono unsaturated fats from different types of sources, plant based and animal sources, and you feel that return, you feel that gene come back and that neuroplasticity and whatnot.   Dan Sipple:  But look, I just encourage people to not over do it either, there's a big ... I feel like there was the plant based movement but then even now with all the carnivore madness going on at the moment, there's a big kickback to people and ketogenic diet, just going crazy on fats and ending up with all these bile issues and digestive issues, which we've gone into in the past as well. So it's a sweet spot. It's like anything, you have to hit the sweet spot. So long as you're doing things like macadamia nuts, avocados, a bit of coconut oil, grass fed beef, if you can get it, venison and deer, especially the men, trust me the next day your body will thank you for it, you know what I'm talking about, when you first wake up in the morning.   Dan Sipple:  But yeah, did you have anything that you would like to add there mate, with your take on that?   Mason:  I agree, just get out of the labels, if you can challenge yourself, it's one thing because I did want to talk a little bit about the fact if throughout this conversation, if there is someone that is really feeling like they've broken out of the dogma of like a vegan or raw kind of style of things, but they're still walking that lifestyle, just make sure we're hitting little points to enable them to maintain as best as they can a healthy cascade. In that sense, the best you're going to be able to do is just continue to hit those plant based fats, especially making sure you're getting an array of macadamias, avos, coconuts, any others that come to mind there?   Dan Sipple:  I probably wouldn't do any more than that. I think in that scenario, you then want to look to your herbs because as long as you're getting the backbone there, which is cholesterol, it's the rest of the process that you have to worry about on a plant based diet, and that's where the herbs can really help influence, maca is fantastic, maca is one of my favourite herbs. Couldn't speak more highly of that for men and female. That's always going to help men and female detoxify those more toxic types of oestrogens. Any oestrogenic kind of reabsorption that you're going to get through the enterohepatic recirculation, which sounds really complicated, but it's just essentially oestrogen getting broken down on its way out for excretion, but then due to certain gut bacteria, getting recirculated and popped back into the system. And ultimately, that can keep you in an oestrogen dominant state.   Mason:  All right, let's quickly hit that for a second, because we're looking at, I talk a lot about liver support and liver supporting herbs ongoingly, being present for women to ensure that their endocrine system remains healthy. Somewhat the liver, somewhat this is an analogy, but being like a conductor in terms of this gets broken down, this gets recycled, that's out, this is going to be reused, nope we want to keep that in circulation, and also just keeping those phases of detoxification open and present, so that then you don't get that bleed over of toxins and to an extent, I think even to the extent like toxic hormones bleeding over into the sex organs. There's a lot to do, from what I understand with women sexual organ issues, but for men as well, really, really key core to ensure that you're not getting these bleed overs of especially oestrogen [inaudible] into the rest of your system.   Dan Sipple:  Well that's right, because even if you've got good detoxification, even if your liver and gall bladder and your bile is all doing a fantastic job at getting that stuff broken down and packaged up in a nice little package ready for excretion, but then it gets down the large colon and then it hits disbiosis and you've got certain overgrowth of species known to basically unpackage that oestrogen, break it all back down and then guess what, it gets reabsorbed through the gut wall, then suddenly, it's back into the blood stream and back into the liver.   Mason:  So we've got a couple of things. We've got like a huge amount of time, but just in terms of what you like seeing included in the diet, we've got a couple of things in helping that through the intestines, we're going to make sure that we don't have disbiosis occurring in that area, so men maintaining a thorough awareness of their gut health. And then on the liver health in just ensuring that those detox pathways through the liver as well as the bile flow is going. Some basic recommendations.   Dan Sipple:  Totally, so I've got things like Schizandra, we've got globe artichoke, we've got-   Mason:  We're looking at the liver right now?   Dan Sipple:  We're looking at the liver right now, from the top-down. Those things are going to be usually as well as helping the liver, helping you stimulate bile. Bile is so, so important there, that's like washing crap through your liver and getting it down into the bowel for excretion.   Dan Sipple:  To your point though, just to hit that off on the head, binders are the important thing to prevent that recirculation. So we're hitting the charcoal, we're hitting Chlorella, zeolite if you like, I'm not such a fan of zeolite, but those first two are my faves.   Mason:  Why aren't you so much of a fan of zeolite?   Dan Sipple:  Zeolite, from certain studies I have looked at, can potentially bind up good minerals as well, and for that reason, and I've seen that happen too. I've seen people do it for too long and end up really depleted across the board, in terms of their micronutrients and trace minerals.   Dan Sipple:  It does do a good job of getting rid of the crap, but it can take out some of the good too. So something like, I tell people, always do your binders right before you go to bed, away from food, away from supplements. Do it as the last thing. So, a tall glass of water with some charcoal or some Chlorella thrown in there, make sure they are good quality.   Mason:  What about the clay side of things? As I said I generally sit, not like one back from the intensity of zeolite, even charcoal, I can't really handle every day because it's just too dehydrating for me, and I kind of feel like it has that same approach. Whereas clay's seem a little bit more gentle.   Dan Sipple:  Clay is something I have had less experience with, so you're probably going to be a little bit more vast in its ability to do that. But it does definitely fall into that same category. I definitely consider that before I hit zeolite.   Mason:  Yeah, okay. Cool. And then maintaining that liver health is something I feel like those staples. MSM is something that I'm still absolute thorough fan of, is that something you're still comfortable with men having?   Dan Sipple:  I do like it. It is very sulfuric, so people on a high protein diet that are already getting too much sulfur, all that have certain snips or SNPs or genetic variations on certain enzymes that predispose them to accumulating sulfur, have to be careful with that one. That's why it's always good to test them and check that stuff out before you just go gnarly on detoxing and those sorts of things.   Mason:  Do a genetic testing?   Dan Sipple:  Genetic testing is good, yeah. Mm-hmm (affirmative). Good old 23 and me run it through a genetic converter, find out if you've got enzymes like the CBS enzyme, that's to do with the transsulfuration pathway. But look, generally speaking, I see it do good things, it's excellent for joint mobility, I know I'm preaching to the choir here anyway, but, yeah. Back to you.   Mason:  Keep the inflammation down as well.   Dan Sipple:  Totally.   Mason:  And then with these things, the reason I like having these conversations because we get into the nuances of particular herbs, nuances of particular mineral supplements like MSM, and if something doesn't have a nuance, and it's just like a broad statement and it doesn't actually have room to move and breathe with all the different constitutions and genetics and tensions we have. Then it's marketing, you're not looking at it deep enough.   Mason:  Okay, so great. Keep up the Schisandra, globe artichoke probably milk thistle falls in there as well, it's like a here and there kind of like ... Helping herbal aid. And then getting down into the digestive system, like binders is just something I'm going to ... You know binders and clays, are in the Shen Nong original Materia Medica, as one of the original tonic herbs. And so we have the reishi's and the eucommia's and the schizandra's and the shatavari's there, within these ... Over 2000 years ago and thousands of years of pouring in, humans, men and women, herbalist and shamans like looking into what's going to be the most life enhancing, life procuring tonics from minerals, animals and plants and mushrooms, that you're going to be able to include in our diet longterm, and there's four different clays in there, that fit into that tonic herbal system as a mineral herb.   Mason:  So, it's something that I don't see as a treatment of myself daily, I see it in that kind of, the way that you see indigenous humans, birds, primates, going and sorting out the clay deposits or finding like here in Australia, the those termite mounds that are high clay, and every now and then, just popping a little bit of that through your tract in order to bind, to not just toxins in the environment, but metabolic waste that occurs just in general.   Dan Sipple:  Which includes hormones, yeah, totally.   Mason:  Which includes hormones. All right, beautiful. Now-   Dan Sipple:  Can I just chime in there Mase.   Mason:  Yeah.   Dan Sipple:  You've brought up a good point. While we're talking about detoxing the liver, and inflammation and whatnot, oxidative stress, iron is such a big, big factor that I never look past when I'm treating males. Obviously men don't menstruate, so we don't have a natural means of losing iron. And a lot of men, particularly those with low testosterone will have elevated ferritin or even elevated serum iron.   Dan Sipple:  Now, there's a genetic condition called hemochromatosis, which some of the listeners might be familiar with. That affects males and females. So, if iron is really high, guys when you've done blood checks in the past and your doctors just gone, "Oh well, we don't really know what to do about that, it's all good. Just check it out in a year." Pay attention because iron, if it's high, it's going to spell a lot of issues when it comes to your hormones. It creates a lot of inflammation, a lot of oxidative stress and just like it does in the environment, it's going to rust out your body and your organs.   Dan Sipple:  So ferritin scores, this could be reference range, western diagnostic range between 30 and 300. You don't really as a male want to be over say 100, 120. The sweet spot I find tends to be around 90 or 100 for ferritin. That's a deep reservoir sources of stored iron. But look, iron, even iron rich foods funnily enough, in a lot of the androgenic foods, beef, chicken, eggs and that sort of thing, naturally are going to contain large amounts of iron. So if you fall into that category where iron toxicity is a thing for you and you work that out and you link that back to why you haven't been able to reach your androgenic potential, that's something that you'll need to individually curve and look at. And again that's going to come back to how well your liver is detoxifying, because of all that iron creating a lot of oxidative stress, you have to be hammering the antioxidants. That's your blueberries, your green tea's and all those liver herbs which Mason and I just rattled off, so your milk thistle, globe artichoke, schizandra berries, rosemary, so forth.   Dan Sipple:  I just want to throw that in there because the dance and the balance between those metals and micronutrients like zinc and iron, you have to get that dialed in, you have to make sure that your zinc isn't being lost to iron, because all those metals are going to compete. Copper, iron, zinc. And zinc, we'll do a little section on that soon, but that is, they call it the male mineral for that reason, it's the one that always is associated with proper formation of your androgens and getting that testosterone converted from progesterone.   Dan Sipple:  So in a nutshell, to cap off from that, check your iron out, it's always good to do a full serum iron panel, iron studies and look at your ferritin scores, if it's a problem for you, make sure you're not taking any iron supplements. Definitely get all iron out of your supplements-   Mason:  You probably shouldn't be taking iron supplements to begin with.   Dan Sipple:  That's right. They do tend to work their way into a lot of the multi-mineral formulas, unfortunately. But there are some companies like Thorn for example, that will do iron free multi-mineral formulas.   Mason:  Okay. You recommend, I know this is like you get down the route of blood letting, which we know maybe it's not happening as much. Or even just going and donating blood in order to alleviate that. I know it's always like a real easy way to, if you're prone to those high iron levels, getting in there and doing something like that, right?   Dan Sipple:  100%, and you'll know it too, because there will be the sort of people that you'll do a consult with, and they'll be like, yeah I went and got my blood test and I don't know what it was, I don't know if it was just because I was fasting that morning, but man, I felt light that day and the next day. And you'll be like, okay. It's going to be interesting to see what your iron scores come back with, and sure enough, a lot of the times they're high.   Mason:  Okay, leading on from that, do you want to talk a little bit more on zinc while we're at it?   Dan Sipple:  I'd love to. So zinc and copper, zinc, the male mineral, copper the female mineral. Little bit sort of, it's not that straight forward but they do have that sort of reputation. We do see in today's society usually a lot of panels where zinc will come back low and copper will come back high. And copper dominance for females and males is an issue, because it definitely will cause a lot of hormonal disruption, brain fog, immune system problems. Any issue where zinc cannot accumulate and build up to a healthy decent level is going to affect immunity, constitution and hormones.   Dan Sipple:  So, zinc as a supplement is always a good idea I think for men, as soils these days are just as fact depleted in zinc. It is hard to get zinc. So a good sort of 30 milligram supplement, but it's also good to test as well. Test and check where you're at. But I just rarely see when we run a zinc panel a mans zinc is like prime and in good shape, it's always like, it could be better.   Mason:  It's always nice, you can, just that connection that it's like, took Tahnee out for dinner last night and of course started with a couple of Sydney rock oysters, like always good to keep the oysters in a high rotation if possible. Don't know where pumpkin seeds sit anymore in terms of actually affecting zinc levels, but-   Dan Sipple:  Yeah, I'm on the same kind of band wagon there. That really got pumped, so I remember when I was at uni, pepita seed, pumpkin seeds for zinc.   Mason:  It used to be on the pepita seed butter.   Dan Sipple:  Yeah, me too.   Mason:  And it's very delicious. But like I don't think there's any drawback, I don't see as many drawbacks. I definitely don't have as many seeds these days in my diet as I used to, but a little bit of that there. But then in terms of supplementation, I think we were talking yesterday, I got a little bit of citrate sitting up there, zinc citrate in that form, which is quite effective. But you like the-   Dan Sipple:  I like picolinate. Picolinate is, I won't talk too much to it because I'm not a chemist, but it's a form of zinc, which the body is going to be able to yield more from essentially. There are studies that actually conflict that too, however. So it's something where you do need to do a bit of personal trial. I do well on picolinate, I don't do well on citrate. Others, they do well on citrate.   Dan Sipple:  Generally avoid the over the counter versions though. I find like zinc gluconate, zinc oxide, some of the cheaper forms of zinc, just you'll probably absorb 10 to 20% of them. You're wasting your money really. But before you supplement, like you touched on Mason, definitely try and stack your diet if you're a man, in zinc rich foods. So we're talking oysters, deer venison, eggs, beef, funnily enough, zinc is found in a lot of the animal foods, it's just a fact. I find that even, and I can hear the plant based community in my head going, but there's zinc in this and there's zinc in that. Yeah, there is zinc in like pepita seeds for example, but there's also phytoestrogens in that same food. And there's also copper in that same food, which is going to make it hard for you to use that zinc.   Dan Sipple:  Whereas, something like good old grass fed beef, it's just bioavailable. Your body will just know what to do with it, and will suck it up.   Mason:  Or even better, like a venison, like wild non-vaccinated venison.   Dan Sipple:  Yes, exactly, yeah. And anything, as I think Sylvester Stallone said it in the 80s, "I'll eat anything that runs, walks, crawls, or flies".   Mason:  Okay. Deep.   Dan Sipple:  Yeah.   Mason:  Can you just, so I can get my head around a little bit of more of the importance of zinc. It's definitely something I haven't really, I'm not doing too may isolated supplements these days, but zinc and iodine was always one that I kind of like had hanging around at least. So can you just talk in terms of the pathway of where zinc is supporting that process of maintenance of health testosterone.   Dan Sipple:  Definitely. So like we touched on before, preventing testosterone from aromatising down to oestrogen. That's the main association there with zinc. If you have poor zinc levels, you can be pretty sure that that's going to be what's happening.   Mason:  Okay.   Dan Sipple:  That's essentially in a nutshell. But I find zinc isn't just testosterone fuel, it's all the other stuff too, like its bone health, its immune function, which is super important for much as male all around health and female too. But specifically the hormones, yeah, it's preventing that aromatisation.   Mason:  And the association between copper and oestrogen?   Dan Sipple:  Yeah, so copper is going to act like a shield for zinc to get on its receptor. So zinc and copper are always, excuse me. Trying to compete for the same receptors. It's a constant battle, and the ideal ratio, no matter what the scores are when you look at them on blood, as long as they're one to one, that's what you're aiming for. So I usually look at plasma zinc and serum copper. But most of the time, I'd say 90% of the time in males and females, we're seeing too much copper and not enough zinc.   Dan Sipple:  The way you remedy that is essentially just by pushing more zinc into the body to help push copper off the receptor sites, but you then have to get it out. So same thing applies what we were talking about before. You have to have good liver health, you have to be sweating, you have to be moving, and you have to be binding.   Mason:  And you've got to be pooing well with the binder.   Dan Sipple:  And pooing.   Mason:  So, that's kind of like a similar conversation, I guess there's always competition and ratios going on in the body. It's a similar thing with taking iodine to get those toxic halogens out of those receptors, right.   Dan Sipple:  It is, it is man. You have to look at selenium, you have to never just blindly take iodine and never look at selenium. You can see that become problematic and you can see, it can be flip side too. I have experienced that where I was on supplements that, and a diet that's naturally high in selenium and all of a sudden, I was creeping into selenium toxicity and my iodine was falling really short.   Dan Sipple:  So, it's always about that dance, you have to, don't just look at one mineral, you have to look at the full array.   Mason:  Okay. What's next down the chain?   Dan Sipple:  Let's have a look. We talked a little bit about soy-boys as they're sort of referred to.   Mason:  The precursor to the conversation guys, just in case you were like, hang on, I didn't hear the words soy-boy, I would have remembered that.   Dan Sipple:  Yeah, that's right. The precursor conversation. I mean, just highlighting that phytoestrogen sources can be anything really in the diet, that does have oestrogen mimicking or oestrogen like qualities, it can be problematic for men. So naturally when men do a plant based diet and they do it for too long, inadvertently, they're going to end up on, not all of them, but some, on foods that do have a high soy intake. Especially if they're not doing it properly and that, we don't need to go down it too detailed, but that's an obvious disrupter to testosterone. It's always going to be an issue there.   Dan Sipple:  And so that's where it pays to do, if you're an honest vegetarian or vegan and you want to do things properly, check out your hormones. Get the data, see what's going on and be honest with yourself and call it into check if things feel out of whack and if you're not feeling good. Because as I said earlier, your genetics are the same as they were all those thousands of years ago. Things have not changed genetically.   Mason:  That's the best thing, we can just all take our way of a charge. I think a lot of people are really emotional in the meat eating community, because they've had their own experiences of being vegan, vegetarian, and done something to themselves and then they feel like they've got to wave the banner. Otherwise, you've got people in the vegan community consistently only following vegan advocates and therefore justifying their diet and going further down that rabbit hole. But if you can take the charge away, get your panels done, don't do it in a sense that's defensive, don't do it trying to prove that one diet is right or wrong, no one is rocking it.   Mason:  There might be a few like indigenous communities that are really kind of making it really work still, but despite, yes we've got that, medical systems they're supporting us at the moment, but we're still everyone is experimenting at the moment in terms of what's going to be ideal in this post industrial world. For health, we're all trying to, we're picking and choosing and scraping things from different traditions and different countries and trying to make that work. So, in that sense, everyone can really get off their high horse-   Dan Sipple:  Yes, on both sides.   Mason:  Yeah, well from carnivore, to vegan. Veganism and everything in between. And if you can take away that charge and just get these panels and not be waving a flag for an agenda, or a justification of what you are doing currently. One of the best things I ever did when I was basically vegan, raw food, was reading Weston Price Natural Degeneration. I looked into the reality of why the China study was pretty horrible. Not horrible science, just horrible correlations that were results that they pulled out of that study.   Mason:  And just because I wanted to take away the charge of trying to justify myself and what I was doing, rather than actually having natural curiosity. Reading those books and reading about all the benefits of animal fats and all those kinds of things when I was vego, that was years before I made the transition. They weren't causative things that made me flip over, they just made me, they just kind of helped balance me out. It's nice to know other points of view, so you don't feel like you have to get defensive with your diet, because that's when you really dig yourself a hole, it's something, I don't exactly, I haven't got my head completely around the physiology of this particular susceptibility, but again, our acupuncturist talks a lot about the fact that when you have excessiveness in your lifestyle and in your diet, excessiveness is generally going to lead towards a deficiency of Jing at some point.   Mason:  And that is going to lead to a deficiency of your neurology and especially when you get to the point when you are deficient in blood, that is when you become susceptible to dogmatic ideas because it's so much harder for you to find your own center, your own Shen, your own mental consciousness, that you need to lean out and rely upon external systems. And because you can't establish the blood, which carries the Shen through your body, then you can't restore your Jing because you put on the blinders for your dogmatic diet or lifestyle factors or whatever it is, and you can't get out of it. And so, it's going to be a slow build out of that, and if you can work, even if you're in a nice balanced place now, consistently having little challenges for yourself to make sure that you are actually living dietarily supplement wise, belief system wise, based on something that is still relevant and innately coming from your center and your family center, rather than an idea that you feel like you've put your chips on and so you've got to make sure that you have all the data to justify.   Mason:  I think that's a huge part of it here, and I think that's all I have to say on that conversation because I really have a lot of friends who are vegan, I really respect the fact that they do that. And they're like, I'm going down this route, and there doesn't need to be any justification of it. But then they're doing the panels, right. They're taking the herbs and they're trying to ensure as much as possible that they're not degenerating their genetics.   Dan Sipple:  Totally, and that's the thing. I work with vegan's, carnivore's, paleo's, keto's, all of them, right. And I have respect for anyone that walks through the door no matter what they're doing, as long as they're being conscious about it, and which feeds into what you're saying. So getting your panels done, being conscious and honest with how you're feeling. If you're honest with your body and it's not working for you, it's okay, you tried it, you gave it a crack and you cleaned out your body, and you're going to revolve it from there. Don't get stuck into the dogma where, that's right, you've just got the blinders on and you can't hear anything. And that's on both sides of the equation too.   Dan Sipple:  If you've gone down that path and you are feeling signs of degeneration and you're skipping meals and you're eating chips and you're drinking beer, but you're plant based. It's like, come on, that's not cool.   Mason:  Or even not that, even if it's not like that kind of like faux health, even if there's no beers and chips and it's all that. There's always obvious signs of degeneration and you want to get to them before, not that it's about other people, but you want to get onto them before it becomes evident to everyone else.   Dan Sipple:  Totally.   Mason:  Because that's what happens a lot. Thanks for going down that little rabbit hole with me. We haven't got too much longer, so I want to hear a couple of other things. We've looked at cholesterol and how important it is, having a reasonable amount of and varied fats, plant and animal. Ensuring not to go excessive as to put taxation on our gull bladder and as well I think we've talked about too much fat is going to lead to an overgrowth of particular bacteria and off gassing, and that's why you see a lot of people who aren't designed for keto or just tend to stay there too excessively, are going to see this dibiosis in their gut. Runny poos and all those kinds of things. That general queasiness-   Dan Sipple:  Yeah, nausea, queasiness-   Mason:  Or it's that little queasiness when you have too much fats [crosstalk 00:59:22]. It's good to be on to that.   Mason:  Now tell me, we've gone down the nature of stress and ensuring that inflammation and stress isn't present, so that we can have that pregnenolone steal, which happens up above and inevitably goes down to forming more cortisol, right? So it's not even that directly cortisol being caused, it's the fact that we've got potentially these shenanigans going on in that hormonal cascade.   Mason:  I want to quickly talk about the formation of vitamin D3. It being a hormone in itself, it's one of the other things that always came up in terms of vitamin D3 levels being very low in people who don't have adequate cholesterol, and that's something that came out of that same conversation about 10 years ago for me, that I was talking about. So, can we quickly touch on the role that vitamin D3 is playing on all of this as well as our testosterone?   Dan Sipple:  Sure. So vitamin D3 isn't actually a vitamin, that's the first thing. It's a hormone. It's a steroid hormone with a cholesterol backbone. So straight away, we get out on the mindset of oh, it's just a vitamin and its good for you. It's like no, it's a hormone and you need it in big quantities. And if you want happy hormones and you want low inflammation, you'd better damn sure be looking at your vitamin D3, and that includes the active and non-active forms when you do blood panels.   Dan Sipple:  Typically, when you go to a doctor, they're just going to look at the non-active form, which is called 25-hydroxy vitamin D. Looking at the activated form is 1,25-dihydroxy vitamin D. And that's the one that the kidneys I believe converts from the sunlight and using sunlight and cholesterol hits your body, boom, goes into the organs, the liver and the kidneys and gets converted. And making sure that you've got a healthy, good level of both ultimately. That's kind of the long and the short of it.   Dan Sipple:  But, I'll say in addition to that, that hormone D, I don't call it a vitamin, I call it hormone D, is the ultimate antiinflammatory hormone in the body. So if you have high cortisol and low hormone D, guarantee you're in trouble. Guaranteed.   Dan Sipple:  Inflammation, we hear a lot about inflammation and it's kind of like people, yeah, yeah, yeah, I get inflammation. But it goes so, so deep in terms of what stimulates inflammation and just how catastrophic that can be to your hormonal cascade. So, inflammation can come from yes, diet, it can come because you're not sleeping, but an often overlooked area is infections. If you have stealth infections in your body, and your po

In our last episode we talked about the differences between PCOS and Adrenal Dysfunction, which is often called Adrenal Fatigue.  Adrenal Fatigue or Adrenal Dysfunction is not a ICD10 diagnosis. There is an actual ICD10 billable code called: unspecified adrenocortical insufficiency (E27.40).  But there is controversy in using this code for patients. It is technically meant for conditions where the adrenal glands do not produce enough steroid hormones such as cortisol and aldosterone.  You might be saying, but this sounds exactly like Adrenal Fatigue/Dysfunction! Most people with Adrenal Dysfunction have normal labs, so their doctor cannot code for Adrenocortical Insufficiency (E27.4).  And because their labs and testing look normal people are told they are fine and dismissed. In this episode, we are going to talk about the testing for Adrenal Dysfunction.  There are some testing that can show Adrenal Dysfunction such as saliva and urine testing.  But most conventional docs are mainly familiar with blood testing. Typical blood testing for adrenals usually will show that a person doesn't have adrenal dysfunction, when in reality, they do.  We are going to talk about the different methods for testing Adrenal Dysfunction.   Let's start by talking about the most common testing method that most docs use, blood testing. Adrenal Blood Testing: Cortisol: Blood testing for cortisol is not accurate.  Most, if not all people with Adrenal Dysfunction will test normal for cortisol blood testing.  The reference ranges are vast and a blood test is only done once or twice in one day. And when you have a needle coming to stab you, automatically the body raises the stress hormones.  So cortisol can be falsely elevated in a blood test. DHEA: DHEA is secreted mainly from the adrenal glands.  In adrenal dysfunction, you will see lower levels of DHEA.  DHEA reference ranges are vast and everyone falls in normal when doing a DHEA total blood test.  But a DHEA-sulfate blood test is fairly accurate for evaluating levels of DHEA in the body. But again, those lab reference ranges are still pretty broad.  But in general, terms, if the DHEA is low or low normal range then you can start to consider that a person has Adrenal Dysfunction. Testosterone: DHEA is secreted mainly from the adrenal glands and will convert to testosterone for females.  In adrenal dysfunction, you will see lower levels of testosterone in women because of the reduced DHEA levels.  In men with adrenal dysfunction, you will also see lower levels of total testosterone. Testosterone reference ranges are very vast.  Quest has a reference of 2-45 for females and for males the reference range is 250-1100 ng/dL. These are pretty big reference ranges.  But if someone has a low normal testosterone level you can consider that person has Adrenal Dysfunction.  Pregnenolone: Pregnenolone is secreted from the adrenal glands and there is a small amount made in the spinal cord and brain making it very neuroprotective.  Pregnenolone is accurate as a blood test. But like DHEA and Testosterone, the reference ranges for pregnenolone is huge. For Labcorp the reference range is anything less than 150 is norma

In this episode,  I'll be sharing with you exactly what the mysterious godfather hormone is, why it's even called the godfather hormone, and many of the things that it can do to help you. This hormone is frequently overlooked even by those in functional and integrative medicine, despite being lauded as a solution to a lot of health issues.Stay tuned as I dive deeper into that to enlighten you on it's great potential in helping anyone optimize their health for the better.Key Points Discussed:The miraculous little hormone that solves a lot of issues in the human body (00:52)The health risks of having low levels of the godfather hormone (03:10)The role of natural killer cells (05:06)The more humane way of approaching the lack of knowledge about treatments (08:48)People who should stay away from Data until the right time (13:52)Additional Resources:www.BrianGBrown.comwww.BrianGBrown.com/Book--My new book will be releasing soon. Be sure to join the Inner Circle now!Happiness Hijackers Inner Circle: http://bit.ly/2wC9esW--To work with Dr. Brown, please visit: http://bit.ly/2Z6r9Ek--Be sure to follow us on Instagram and Facebook!--You can find the podcast on Apple, Google, Spotify, Stitcher, or wherever you listen to podcasts.If you haven't already, please rate and review the podcast on Apple: Podcasts!

In this episode,  I'll be sharing with you exactly what the mysterious godfather hormone is, why it's even called the godfather hormone, and many of the things that it can do to help you. This hormone is frequently overlooked even by those in functional and integrative medicine, despite being lauded as a solution to a lot of health issues.Stay tuned as I dive deeper into that to enlighten you on it's great potential in helping anyone optimize their health for the better.Key Points Discussed:The miraculous little hormone that solves a lot of issues in the human body (00:52)The health risks of having low levels of the godfather hormone (03:10)The role of natural killer cells (05:06)The more humane way of approaching the lack of knowledge about treatments (08:48)People who should stay away from Data until the right time (13:52)Additional Resources:www.BrianGBrown.comwww.BrianGBrown.com/Book--My new book will be releasing soon. Be sure to join the Inner Circle now!Happiness Hijackers Inner Circle: http://bit.ly/2wC9esW--To work with Dr. Brown, please visit: http://bit.ly/2Z6r9Ek--Be sure to follow us on Instagram and Facebook!--You can find the podcast on Apple, Google, Spotify, Stitcher, or wherever you listen to podcasts.If you haven't already, please rate and review the podcast on Apple: Podcasts!

It's Episode 440, Q&A #33 time! Submit your own questions for the podcast at: https://robbwolf.com/contact/submit-a-question-for-the-podcast/ Individual question videos are linked in each question title, but if you want to see the complete video for this podcast, be sure to check out our YouTube channel.   Show Notes:   1. Chocolate-Coated Peanut Diet? [2:18] Troels says: I normally base my diet on paleo principles, but for the past month, I have been eating roughly 400 grams of sugar- and chocolate-coated peanuts a day. This should be unhealthy, but my digestion has improved after having been out of whack for months because of SSRIs, and I have consistent morning wood which, mainly due to SSRIs has been rare. Despite eating more than 2000 kcals just in candy each day - half of which is sugar - I still look lean (almost too lean), and, if anything, I'm adding muscle. I notice a small sugar high and subsequent low, but that's pretty much the negative effects. Also, by doing this, I'm ingesting good amounts of Mg and Zn (~400 mg and ~10 mg). I'm male and 32 years old. Two questions:  - Am I doing too much latent damage for this to be a good thing, or could it be that this could work for some people, at least for some period?  - How do I make sense of obesity epidemics, the grocery shoppings of fat people, and energy balance when I can consume much more than 2700 kcals a day and stay lean? (I don't think I work out much, and many days, I also eat an energy rich evening meal.)   2. DHEA and Pregnenolone Supplementation? [12:08] Jason says: Rob - 45 year old male. Job is sometimes stressful but for the most part I get 8 hours sleep and follow a lower carb paleo diet 6 days out of 7. Been doing this for close to a decade. I’ve been experimenting for a year or more with Pregnenolone and DHEA in varying amounts. When I take preg in doses of 200-400 mg before bed I feel great and everything works really well.  Focus, mind and man things. Same if I take 100mg or so of DHEA. I’ll use these on weekends mainly and not so much during the week. I notice during the week without them I tend to be bitchy and emotional with low sex drive. If I take Preg or DHEA these issues go away. I’m afraid I’m taking too much or somehow dependent on these supplements now. What should I be looking out for or the downsides to these substances?  I feel like I’m playing with fire.   3. How To Know If Keto is Right For Me? [16:28] Radu says: Hi Robb, I would like your opinion regarding how would somebody decide if the ketogenic diet is beneficial or not, or if you have recommendations for tailoring a ketogenic diet to people with increased cholesterol reaction to this diet. Are there relevant tests that can help in deciding in this regard? In my family health history there are lots of cancers, some heart disease, and some neuro-degenerative (Alzheimer) disease. I am 48 years old, caucasian, in very good health and decent physical shape. My diet is a loose paleo type (occasional milk and grains) and I have no allergies. I would like to have some periods of ketosis, as I feel some benefits from it, but I do not know how concerned I should be. ****** Thank you for taking the time to read the question. I totally understand if you do not have time to answer this question directly, but I find this subject is not cover with enough clarity. Maybe you can touch on this in your regular podcasts when discussing related topics. To understand the background of my question: I experimented with Ketogenic diet a couple of times, and I felt great. My main reason is general health and well being, with an accent on mental clarity. This aspect was improved by the Ketogenic diet. Unfortunately my cholesterol had some unexpected behaviour: My 1st Keto experiment: I was in ketosis from Feb 15 to April 15, 2015, below are the blood tests before the diet and 9 month later. Date            Total_Ch LDL   HDL Non_HDL_Ch     Triglycerides 12/15/2014  194 125        58 137               254 12/22/2015 178           101 58 121                         44 So far so good! Encouraged by these results, I repeated the diet 1 year later, but this time I tested myself while in ketosis. After 1 ½ month of ketosis, I did my 1st blood test (3/1/2016). I repeated the test (still in ketosis about a month later (4/7/2016). This time I also measured the ApoA1 and ApoB, and the numbers only confirmed the cheap test. I stop the diet, and 8 month later (12/29/2016), the values are back to normal-ish. Date             Total_Ch LDL HDL        Non_HDL Triglycerides ApoA1(g/L) ApoB(g/L) 3/1/2016       321 232      75 -             31 -         - 4/7/2016      298 230     55 243         30 1.69         1.18 12/29/2016  212 124       66 145         47 -             - I measured my ketons level with Keto-sticks. The level was on average at 2, with variations from 0.5 to 4, depending on the diet macro-ratio and mostly on physical activity level. Blood work: https://www.specialtyhealthwellness.com/offer/robb-wolf-wired-eat-panel/   4. Genetics & Body Composition? [28:57] Sara says: I know genetics have a large part in how our bodies form and react to foods, the environment, etc. But how much do we have control of when it comes to body composition? I am in my mid-thirties and have always been athletic and a focus on healthy eating, now Paleo focused. However my weight - while I am still in a healthy range - doesn't budge easily despite my efforts. And it's been like this ever since my teens. I don't want to compare myself to others - but it is frustrating when I eat so clean, am active with weights and cardio and the person next to me has a slimmer waistline and eats fast food and rarely exercises. I know can become slimmer with extreme effort - but those extreme efforts are not good to my body and I dont want to add additional stress. Should I just "give up" and not fight my body and just focus on my healthy living or do you think I can loose some extra fat without extreme measures? About Me female 37 5'7 147-155 lbs Body Fat % ~18 (16-20 depending on the test) Athletic build, muscular legs and upper body, chubby midsection that rarely firms up I have SIBO/Gut Issues Paleo/Low-Fodmap (I cycle IF 16:8 or 18:6 and sometimes Keto) Heavy Weight Lift 2xweek, HIIT/OTF 2x/week, Steady state cardio (walk/jog) 2x/week If I breathe on peanut butter or eat too much Paleo granola I gain instantly and have to go back on strict IF/keto but my midsection is never "firm"   5. Ketosis and Carbohydrate Timing? [35:50] Ryan says: Hi Robb. I don't know if this will reach you, but while listening to your podcast and reading your first book, a hundred questions pop into my head. This is one of them. I thought about asking my doctor, but I knew a blank stare and a sweaty forehead would be his answer. So here goes: Does frequency of carb intake play a role in disrupting ketosis? For example, if I am going to eat 150 grams in total of carbohydrates today, will eating all 150 grams of carbs at the same meal knock me out of ketosis for an EQUAL amount of time as eating 15 grams every hour for 10 hours?* My theory is eating 15 grams of carbs an hour for 10 hours will be just enough to keep a person out of ketosis for a longer period of time than eating all 150 grams in one meal while carb-fasting for the rest of the day. I could be wrong, but that's why I'm asking the master. Thank you in advance for any time you can dedicate to this question. Have a great day.     Where you can find us:   Submit questions for the podcast: https://robbwolf.com/contact/submit-a-question-for-the-podcast/   Transcript: Download a copy of the transcript here (PDF)

Have you heard of pregnenolone, the “mother of all hormones?” Wondering about the concept of the pregnenolone steal and whether this applies to you? Want to know how to balance pregnenolone for optimal hormonal balance? Tune in to hear Ali and Becki break down symptoms of low pregnenolone and provide practical guidelines for testing, supplementation and food as medicine recommendations for optimal hormonal balance.   In this episode, Ali and Becki break down the function of pregnenolone from its role in sexual hormone and cortisol production to its applications for neurological disorders, depression and beyond. Learn about the role of cholesterol and why having too low of cholesterol can negatively impact your hormonal balance. Plus learn why supporting the detox process and reducing stress is essential to balanced pregnenolone levels in the body.   Also in this Episode: Ali’s UpdatesSign up for our newsletter here to stay up to date on the latest events and happenings! Preorder The Anti-Anxiety Diet Cookbook Virtual Food As Medicine Keto starts July 3rd! KetoCon Tickets on Sale Now What is Pregnenolone? The Cholesterol Connection How Does Pregnenolone Get “Stolen”? Symptoms of Low PregnenoloneEpisode 126: Keto Cardiologist Dr. Nadir Ali Episode 92: DHEA The Fountain of Youth with Guest Stephen Cherniske Testing for Low PregnenoloneNeuroHormone Panel CardioMetabolic Panel Treating Low PregnenoloneStress Manager Bundle Adrenal Rehab Bundle Relax & Regulate B Complex Liver Function and Hormonal BalanceEpisode 109: Liver Function Real Food 10 Day Detox Ultimate Detox Episode 84: The Importance of Detox on Keto This episode is sponsored by FBomb, makers of high-quality fat-fueled snacks and products like macadamia nut butter packs and premium oils as well as their new Keto Krunch. Click here for more on why I love FBomb!  

Are you making sure that you have a good quality source of fat at every single meal? When talking at Z Energy during the week, some of the questions around this topic reminded me that we all need to know what we want - good sources of fats. Also, who still holds the old thoughts of "if you eat good quality fats, you will get fat"? All of you who see us in clinic now know that this isn’t true at all. Instead, you end up eating less when eating good quality fats. Marlies reminds us of some of the reasons why we need good quality sources of dietary fats: Every single cell in our bodies is made from fat.The surrounding of the cell is made up of cholesterol. Where do we get cholesterol from? Yes, our bodies naturally make it, but we also need good quality fats for it. It’s the best source of energy.Our bodies run off fat. As I shared at Z Energy this week, the fastest way to getting better energy is eating good quality sources of fats. Dietary sources of fats bring down inflammation in our bodies. Our hormones run off good quality fats.Do you want easier periods? Eat more good quality sources of fats. All steroid hormones are made up from cholesterol, specifically LDL cholesterol (aka “bad” cholesterol). Pregnenolone, estrogen, progesterone, testosterone, cortisol, DHEA are all steroid hormones! Pretty important, right? Remember, our brains are also 70% fat!!!We need good quality sources of fats to feed our brains. In the online course Finding the Fully Functional You we have gone deeper and started talking about the quality of fats that we are using to cook in. This is really important. The best fats to cook in are ghee and coconut oil.Who cooks in butter? Especially when making sweeter things right? Well Marlies has clearly explained why you don’t want to cook in butter. So butter has a low cooking point, then it turns brown so the structure changes because butter has milk solids and sugar so it turns toxic. Have you heard that Avocado oil is great for cooking in? However, it is an omega 9 and monounsaturated, so also an unstable source for cooking. It will turn toxic. If you want to cook in olive oil then, the Danes Sautéing is preferable. Also, just something for you to ponder: it’s actually really hard to get enough fish into your diet. How many servings of fish do you have a week? This could be something to focus on as I know most people we see in clinic aren’t eating enough fish. The other problem is getting good quality fish as well. You want to make sure it’s fresh and not farmed, and not fed grains. As much as I don’t like saying, we need to supplement with things. Sometimes when nature can’t provide it the way we need it due to demand and the environment, you might need to supplement with it. I personally do supplement with fish oils, but remember, you always want to keep everything in balance. So it’s worth testing it as your body does change. You always want a balance of omega 3, 6 and 9. Can’t wait to see your latest fish recipes and photos posted on our Facebookpage!

¿Qué te hace envejecer prematuramente? El estrés, por supuesto. En este episodio hablo de diferentes técnicas físicas y mentales para manejar y controlar el estrés, para que puedas tener un mejor día y logres bienestar en tu vida. Algunas de estas técnicas que presento son, Sanación Pránica, Hemisync, meditación, respiración, y otras. Además, hablo de la hormona pregnenolone, que ayuda a crear otras hormonas, y que hacer para apoyarla y evitar el efecto dominó que te lleva al desbalance hormonal.  Finalmente, te recomiendo hierbas adaptógenas proveyendo lo que tu cuerpo necesita, para bajar el estrés.  Si quieres aprender diferentes maneras sencillas que te ayuden a bajar el estrés, este episodio es para ti.

LLA Ep. #232: LLA Show fan favorite guest, Dr. Mark Gordon, returns to discuss the following: Dr. Gordon shares his recent trip to Southeast Asia, and talks about the growing demand for hormone optimization in Vietnam, Thailand, and Cambodia Dr. Gordon describes his sleep pattern and how having optimized hormones can make getting 8 hours of uninterrupted sleep difficult for him Dr. Gordon talks the importance of DHEA, melatonin, and addressing inflammation in the brain What is the relationship between thyroid function and depression What is the importance of Glutathione  How important is mineral supplementation in terms of hormone optimization How has pregnenolone been a game changer for Dr. Gordon's patients and how can it help with narcotics and alcohol withdrawal, sleep disorders, as well as helping to address anxiety What percentage of hormone levels does Dr. Gordon look for in terms of hormone optimization for his patients When can "thoughts and prayers"actually be beneficial to hormone optimization Why do men need estradiol and testosterone for optimal libido Why does Dr. Gordon feel the total testosterone number is worthless and focuses on the free testosterone All this and much more: Links & Resources mentioned in the show: Listen to ad-free LLA Podcast Premium Episodes for Patreon Subscribers Only. Become a monthly supporter via $5 or more on Patreon: http://www.patreon.com/llapodcast Project Child Save: http://projectchildsave.org Warrior Angels Foundation:http://warriorangelsfoundation.org Purchase Aggressive Strength products: http://strengthbymahler.com Purchase Aggressive Strength Bundles:  http://budurl.com/mahlerbundles Purchase New Warrior Training products: http://newwarriortraining.com Dr. Gordon's site: https://waftbi.org & https://tbimedlegal.com Listen and download archived free episodes at  http://strengthbymahler.com or http://newwarriortraining.com.  also subscribe, download, rate & review us at: iTunes: https://itunes.apple.com/us/podcast/live-life-aggressively-podcast/id646524617 Stitcher: http://www.stitcher.com/s?fid=34706&refid=stpr Also, be sure to "like" and connect with us on our Facebook fan page at http://facebook.com/llapodcast. 

Have you heard of DHEA? Want to know why biochemist Stephen Cherniske calls it his favorite molecule? Wondering whether supplemental DHEA might be the anti-aging and weight loss boost you need? Tune in to hear Ali and Becki interview Stephen Cherniske for his second time on the podcast talking all about DHEA, the most abundant circulating hormone in the human body.   In this episode, Ali and Becki tap into Stephen’s expertise in the area of anti-aging and metabolic health. Learn why DHEA is considered the most comprehensive repair signal in the body, yet receives very little attention at the clinical level. Learn about Stephen’s personal experience with DHEA supplementation, why reference ranges should be thrown out the window and how supplementation with proper monitoring can be a game changer!   Also In This Episode: Episode 73: CBD with Guest Stephen Cherniske Assessment of DHEA Weight Loss Plus Panel (assesses DHEA-s) Neurohormone Complete Panel (assesses salivary DHEA) DHEA and KetosisFood As Medicine Virtual Ketosis Class Dosage and Forms of DHEA supplementation Optimal Reference Ranges The Role of Pregnenolone and DHEA in adrenal FatigueAdrenal Rehab Bundle   More about Stephen Cherniske:   Stephen Cherniske has been a university instructor in clinical nutrition, served on the faculty of the American College of Sports Medicine, and directed the nation’s first Federally-licensed clinical laboratory specializing in nutrition and immunology. Stephen’s ability to translate technical scientific data into “apple and orange” language is extremely valuable for anyone trying to separate the facts from the fads. He is a patent-holder in the field of biotechnology and is considered the primary architect of the Metabolic Model of Aging. He is author of: The DHEA Breakthrough in 1996, expanded upon in The Metabolic Plan (2003) and further examined in The Metabolic Makeover (2014).   You can find Stephen and more information here: The Metabolic Makeover The Healthy Skeptics My 2048.com

Jim Goetz Chantea Goetz Dr. Mike Brandon How Do I Boost My Testosterone? Jim Goetz There are ways to boost ones testosterone and ways not to. The most common ways individuals (mostly males) look to boost their testosterone; in actuality has no effect on boosting any testosterone but is phenomenal in lowering ones bank account. This is through supplementation. Before taking any supplement, if you are tested in any athletics, ensure you are well within the World Anti- Doping Association (WADA) regulations. If you are a teenager or individual in their 20's, your testosterone levels are already most likely super high. A secretagogue supplement purchased over the counter is not going to raise your levels anymore than they already are. The only thing that can happen if you increase testosterone levels when they are already super high is to shut down your body's own natural production and as a result, make you reliant on exogenous testosterone for the remainder of your life. It sounds fine now but when you are a 40 year old male whose physiology is that of a 90 year old- you may reconsider this as being a good idea. The hype of advertising for these supplements is insane. Know fact versus hype.  There are a crapton of supplements on the market that make claims to boost ones testosterone. In reality these overhyped and over marketed supplements are garbage. They have inferior ingredients that fail to stimulate the natural production of testosterone. First lets do a brief overview on total testosterone levels to get a bit of an understanding on what is being looked at to be increased. Tightly bound testosterone- 2/3 of testosterone is bound to sex hormone binding globulin. The human body is incapable of utilizing this. Loosley bound testosterone- 1/3 of testosterone is bound to the protein, albumin. Some of this testosterone is able to be utilized but not all of it. Free testosterone- 1% to 4% of testosterone floats freely in the blood, able to bind to androgen receptors as the enzyme 5-alpha-reductase converts this free testosterone into hihydrotestosterone, which is a very potent androgen. Some nutritional supplements inhibit CYP19A1, which is an aromatase enzyme. An anti- aromatase actually can act as a testosterone booster in men as testosterone is converted to estradiol, which is then converted to estrogen. Yes, the more testosterone men have, the more estrogen they have and this goes for women as well.  Now men actually do need estrogen (in lesser amounts than women). So when estradiol is low, testosterone is naturally increased. Therefore, if an individual were to lower their estradiol levels, testosterone will be increased. This is a negative feedback loop of hormones. However, in pre-menopausal women, as ovaries produce the majority of estrogen, aromatase inhibitors are less effective (but not ineffective) than in men. Some supplements that are supposed to increase testosterone act on the testicles. Others act on the hypothalamus in the brain. Those that act on the testicles could effect HPTA stimulation (causing testicular atrophy (or shrinkage). Other supplements acting on the hypothalamus cause symptoms of that some may call adrenal fatigue. The most boring ways to increase testosterone are quality sleep (and I do stress quality), moderate physical activity, and weight management. Individuals who stay up too late to watch a game while they rise early in the morning, work a desk job, have a little belly (dad bods or more) and fail to engage in moderate physical exertion for a minimum of three days per week at 30-45 minutes of actual movement, are destined for low testosterone levels and as a result, a lowered quality of life and perhaps lower life expectancy. Lowered testosterone levels have been attributed to lowered libidos, the development of metabolic syndrome- x, and depression (to name a few symptoms). Middle aged and older men have a natural decline in testosterone by 0.4% to 1.6% per year. Some experience lower than average testosterone levels as young as 30. This is why anti-aging therapies have become so important to increase vitality and longevity in individuals. What's the point of living if ones quality of life sucks? Contrary to popular belief, there is no single one best level of testosterone! Different lab results vary as a wide range of free testosterone levels are used between different labs. An example of this is one male was tested at 360 ng/dL. He is lethargic, depressed and cannot seem to lose an ounce of body fat. Another male was tested at the same testosterone level. This individual is confident, successful, full of energy and looks like an adonis.  A few supplements have been shown to increase testosterone. But before they are disclosed, there is a caveat on them. As previously discussed in a podcast, there is a bell curve of optimal levels. Too little of these levels in your body and you will greatly benefit from a supplement. Too high levels of these in your body and the supplement will begin to give adverse effects. The first supplement is vitamin D. Yep, good ol' sunshine. Vitamin D is essential for the development and creation of a multitude of hormones to include testosterone. Enough research has been done to back this up. The second supplement deficiency is zinc. Zinc is lost through sweat so athletes may need to get their levels of zinc checked to see if a supplement may be beneficial to improve testosterone levels. Zinc rich foods include meat, some grains (whole new caveat on how grains are linked to cancer development) and nuts (stick with walnuts and almonds to avoid the excess lectethins or heavy metals). Another supplement is magnesium. In the United States, it is understood most are deficient in this vital mineral. Magnesium both directly and indirectly aids in the conversion of vitamin D into it's active form to be used in the body. Like zinc, magnesium is lost through sweat. A favorite food of this authors that contains a plethora of bioavailable zinc is 100% cacao. If taking a magnesium supplement, one should avoid magnesium oxide, which is only bioavailable at a rate of 4% in humans.  Maca is marketed to increase testosterone. However, maca has been shown to increase libido but not testosterone. Be wary that just because one is in the mood more than usual does not mean that one has higher testosterone levels. The same may be said about horny goat weed. A good form may over time improve sexual desire but has no effect on testosterone levels. D- aspartic acid had some prelimiary research showing increased testosterone levels. However, further studies have showed the opposite of it not effecting testosterone levels whatsoever. DHEA is a hormone that converts directly to testosterone. Individuals with low levels of both have shown an increase with DHEA supplementation. Pregnenolone, which is synthesized from cholesterol, provides a building block for many of the steroids present in your body. Athletes may take this hormone to hide their use of anabolic steroids. However, as this does convert directly to DHEA; some studies have shown increased testosterone and estrogen levels in both deficient males and females. Some pure forms of tribulus such as the original Tribestan might actually have increased testosterone. Unfortunately most of the stuff on the market today is garbage. If you can put it on your fingers and simply blow it off like a powder, it's either not tribulus or it's a terrible form. It should be a tar-like consistency made from the root, not the leaves of the plant.   HOW TO DETERMINE HIGH QUALITY TRIBULUS There's a plethora of other ingredients that are thought to increase testosterone. There's not enough human research on some SARMS such as RAD-140 (testabol) When it comes down to it, plenty of rest, adequate nutrition, moderate exercise and a way to decompress stress and testosterone levels will raise up. During your middle aged years, you may consider seeing an anti-aging specialist to ensure your testosterone levels are where they give you the greatest out of life.   How to Wash Fruits and Vegetables to Rid Them of Neurotoxins   Dr. Mike Brandon ​Jokes have been made about what clean eating is, and how the simplest answer is that it's when you wash you food before you eat it. All kidding aside, especially when it comes to produce, this is a highly suggested action with the justifications mainly being to remove dirt, pesticides, and bacteria. With one quick internet search, multiple sources will say to lightly rub the produce under cold water for 30 to 60 seconds. What's interesting to me is how to wash your hands for that result, it's suggested to do it vigorously for about double that time. So either we should have our hands more clean than the produce we eat, or there's a fallacy or assumption somewhere here. ​ Multiple studies on both washing our hands and washing produce show that most of the cleaning aspect of the process is from the friction of rubbing the dirt and grime away more than the soap use. With produce, using most soaps can actually add a small residue layer on the produce, or even have the soap seep into the flesh of the fruit/vegetable, so this practice is discouraged and you are probably better off rubbing vigorously with running water. Naturally this wont work for all produce, as you can only rub berries so hard before it turns into juice. A larger concern over dirt and grime on our food supply is the pesticides and herbicides that are sprayed on them. These are the only toxic substances released intentionally into our environment and they have the sole purpose of killing living things. There are over 15 common pesticides used, and it is almost never just 1. These sprays are very well known to be neurotoxins and have been linked to Parkinson's disease, asthma, cancers, leukemia, thyroid and infertility complications, and autism, to just name a few. These neurotoxins also appear to destroy many of the antioxidants in produce, as seen by the difference in content of organic vs standard produce.  The most common reason as to why people switch to organic is to avoid these pesticides, but unfortunately, they are still there, but about 70% less. This can occur due to wind and water runoff from 1 farm to the next, or from the soil itself. These neurotoxins absorb into the soil, and many have a half life of 4 to 5 years. So even if no sprays have been used for 10 years on the soil, they could still be being absorbed into the vegetation. So what can we do to limit the amount of toxins we digest from trying to be healthy by eating our fruits and veges? A study was done comparing the ability of tap water, a Clorox bleach solution (which is the industrial standard to wash produce before going to the stores), and a soak in baking soda for 12 to 15 minutes to remove pesticides. This study looked at 2 common pesticides, thiabendazole and phosmet.  Baking soda did appear to clean off the majority of both of these pesticides, especially compared to the other methods which is great news, but it comes with a few catches and precautions. First of all, it did not remove what was absorbed into the peels of the fruit, and assuming, if pesticides go into the peel, its likely going into the flesh as well. Also in this study they took organic fruit and then sprayed it down with thiabendazole and phosmet, which is a decent method to try to replicate a farm, however, if these apples were sprayed in the study a few hours or even days before the cleaning process, how much more is absorbed or harder to remove from produce that was sprayed weeks prior before it even made it to the grocery shelf?  Even with the forward movement towards more organic food, there are still a few scary statistics that show the extent of this public health issue. Chlorpyrifos, which are in the same pesticide family as organophosphates and has the same neural damaging mechanism as nerve gases used in the military, is found in the urine of 93% of Americans! It's estimated that only 1 out of every 10 Americans eat enough produce, which can make this a little more alarming that either we are getting them in our bodies from another source, or the little bit that we eat is still being absorbed and metabolized by us. Then DDT, which is a pesticide that was banned in the 1970's, was found in 99% of Americans. It's illegal to use and is still getting into literally almost all of us. So since we are still getting these toxins in our body, what is there being done to help off set this? There's actually quite a few alternatives to pesticides, insecticides, herbicides, etc, but the difficult part is getting the large farms to jump in with it. Smaller farms in the USA, and most farms outside of the country use a few methods which are cost effective and work. Polycutlure is one method that is used quite frequently. Basically how many home gardens have multiple types of produce in 1 area, that's the concept but on a large scale. Instead of having acres of corn, it would be acres of corn, cucumbers, broccoli, etc. Having multiple types of plants together has been shown to both decrease many pests that only target 1 food, as well as increase the overall immunity of plants to deter more pests and make sprays less required. Trip crops, or sacrificial crops, is another method. Think of a child that is staring at a plate of broccoli and a bowl of icecream; most children will go for the ice cream. That's the concept. Putting “ice cream” type crops in the field to attract the pests away from the yielding plants. Examples are: Nasturtiums  distract aphids (black fly, green fly, white fly). French Marigold helps to attract slugs, thrips and nematodes. Radish  attracts flea beetle and root fly. Then there is also Entomopathogenic fungi, which are parasitic to most insects. The spores will attach to the majority of insect kind, and rather rapidly kill them off and has appeared to be effective in drastically lowering the procreation rate of bugs.  Obviously going organic and washing our produce effectively is better than not at all, and is recommended, however, the environmental and physiological impacts are still a major concern, but at least there are a few methods we can use to help lower the amount of “-icides” that our body absorbs. biohackhumans.com   Find us: Instagram (@biohackhumans)  Facebook (@biohackhumans) Twitter (@biohackhumans) Tumblr (@biohackhumans)   Contact Us: support@biohackhumans.com

What is pregnenolone? It is a steroid hormone but is not a reproductive hormone like estrogen or testosterone.  Pregnenolone is also made from cholesterol, which makes it a steroid hormone. It is also considered to be a pro-hormone,' because it can convert into other hormones depending on the needs of the body. Recently, it has been discovered that pregnenolone is also produced in the brain and spinal cord, which makes it very potent on stimulating the central nervous system and having an impact on the brain. Pregnenolone is helpful for memory. It is stimulating to the brain for memory and learning, but at the same time, it is also neuroprotective.  The brain is very complicated, and pages could be written on the process of memory foundation and degradation. What we are trying to say here is, pregnenolone helps with learning and also preserving memory by protecting brain cells. Other helpful uses for pregnenolone: Memory: short-term Brain fog Mental energy and mental motivation Helpful for learning new information Mood Focus Pregnenolone, like most hormones declines with age. However, pregnenolone can also drop in response to high levels of chronic stress.  Whether that stress is mentally induced such as dealing with a family member's illness, PTSD or a stressful high paced life. Or physical stress such as intense daily cardiovascular exercise can diminish levels of pregnenolone.   This is also known as ‘pregnenolone-steal.'  In times of chronic stress, the body will shunt the production away from the other steroid hormones to produce more cortisol.  For women, the body will shunt production away from progesterone to make more cortisol.   You can test for pregnenolone levels in the blood, but the lab reference ranges are so vast that most everyone will fall in normal ranges.  Quest has a reference range of 22-237 ng/dL, and LabCorp's is anything less than 151 ng/dL. Both are broad reference ranges. I like to see pregnenolone 80-100.  If a pregnenolone blood test is less than 80 ng/ dL, I will treat the patient with pregnenolone.  And after being on the pregnenolone for 1-3 months, I will retest the blood work to see where their levels are and how they are feeling.   As we all know, too much of a good thing' is not-so-good.  Taking too much pregnenolone can have side effects.  There is not a lot of research on pregnenolone.  There are some animal studies but not any real prolific human studies. For the layperson, there is not a lot of information about pregnenolone online. There are some contradictory statements on dosing, side effects, and safety. What I can tell you from my experience with patients, there are relatively little side effects with pregnenolone, as long as you keep the dosage uniquely prescribed for the patient based on their symptoms and the blood work readings.   Pregnenolone is available over the counter/online without a prescription.  Many pregnenolone doses are just way too high.  I have had new patients walk into my office, and they are on 100mg or more of pregnenolone per day.  There are a few exceptions based on

What is pregnenolone? It is a steroid hormone but is not a reproductive hormone like estrogen or testosterone. Pregnenolone is also made from cholesterol, which makes it a steroid hormone. It is also considered to be a pro-hormone,’ because it can convert into other hormones depending on the needs of the body. Recently, it has been […] The post What is Pregnenolone Used For? | PYHP 035 appeared first on Progress Your Health.

We spend very little time on male reproductive health, and a lot of men are in dire need of it. What are some of the factors that physicians should be tracking? How are the side effects of short term memory loss and anxiety on testosterone mitigated? What is the first thing that needs to be done in the case of a patient suffering from a metabolic emergency? On this episode, we are joined by author and physician, Dr. Rob Kominiarek to discuss insights in testosterone and health. You have to use Aromatase Inhibitors very strategically to solve issues. -Dr. Rob Kominiarek Takeaways Complications from fractures of the spine kill more people than heart attacks, strokes, and cancers combined. The doctors that put you on an Aromatase Inhibitor straight out of the gate don’t know what they’re doing. Insulin and growth hormone compete for the same receptors and insulin. At the start of the show we talked about why there’s no one-size fits all approach to optimization, and how to deal with patients who experience anxiety and panic attacks. Next, we talked about what so many doctors get wrong when it comes to Aromatase Inhibitors and why men need estrogen.    We also discussed: How to get insulin levels in check with testosterone The importance of doing Dexa Scans Why almost every diabetic medication is a peptide   There is no single recipe for testosterone optimization. An individualized approach has to be taken. That’s why it’s critical for a patient to get labs to determine what they need. Some physicians put patients on Aromatase Inhibitors right away, and this is a mistake. A lot of the side effects and problems we see on testosterone can be solved by adjusting dosage, not bringing AIs into the mix.   Guest Bio- Dr. Rob is a bestselling author and physician with an expertise in Interventional Age Management Medicine and BioIdentical Hormone Optimization. Interventional Medicine focuses on optimizing your health and enhancing your quality of life while simultaneously reducing the risk of heart disease, stroke, diabetes, cancer, bone fractures, dementia, and other disorders of aging. Go to renewhealth.com or find him on LinkedIn https://www.linkedin.com/in/robertkominiarek/.

The fine and gross motor controls of the hands help to grow the brain.  This brain growth occurs specifically on the surface of the brain (cerebral cortex) as well as certain anatomical areas of the hippocampi structures, the corpus collosum and the cerebellum.  Science has proven that the growth of myelin occurs with improved procedural memories.  When the myelin thickens on the axon sheaths, chemical changes occur and the master steroid called Pregnenolone is produced.  This is part of the Steroidogenesis process that helps to maintain homeostasis within the brain.  The brain has the ability to create new neurons in a process called Neurogenesis. There is now much evidence to support that the brain has much greater plasticity than previously recognized.This is encouraging news for anyone dealing with mild cognitive impairment. People dealing with Parkinson's  can be inspired to become more proactive with the issues of doing certain brain exercises that can help to rewire both hemispheres. One of the tenets of the Whole Brain Power system is to work on ambidexterity with handwriting drills and to also work on mirror writing.  This exercise is called "Da Vinci writing."  It is one in which the practitioner writes from right to left with cursive penmanship.  The other ambidextrous drill is to bounce a golf ball off a mallet and to do so with either hand.  People with Parkinson's seem to make tremendous strides in these areas where initially they had coordination problems.   

Learn How the Measurement and Use of Hormones Can Break the Cycle of Intractable Pain Dr. Forest Tennant, MD, DrPH, is an internist and addictionologist who specializes in the research and treatment of intractable pain at the Veract Intractable Pain Clinics he founded in West Covina, California. Dr. Tennant started his pain clinic in 1975. Originally he focused on treating the pain of cancer and post-polio. He has authored over 300 scientific articles and books, and currently serves as Editor Emeritus of the journal Practical Pain Management, the nation's most widely circulated pain journal for physicians. He has formerly served as a Medical Officer in the US Army and US Public Health Service. In the past he has been a consultant to the US Food and Drug Administration, National Institute on Drug Abuse, Drug Enforcement Administration, LA Dodgers, National Football League, and NASCAR. He has authored a handbook for pain patients called "The Intractable Pain Patient's Handbook for Survival." He is also the creator of the website Pain and Pain Management, a web site dedicated to pain patients which has an excellent selection of articles for physicians and pain patients on pain managment including the excellent review article, "Human Chorionic Gonadotropin in Pain Management." Download or Open: