Podcasts about cocs

NEWS: 35 party-lists unaccredited but still filed their CoCs | October 11, 2024Subscribe to The Manila Times Channel - https://tmt.ph/YTSubscribeVisit our website at https://www.manilatimes.netFollow us:Facebook - https://tmt.ph/facebookInstagram - https://tmt.ph/instagramTwitter - https://tmt.ph/twitterDailyMotion - https://tmt.ph/dailymotioSubscribe to our Digital Edition - https://tmt.ph/digitalSign up to our newsletters: https://tmt.ph/newslettersCheck out our Podcasts:Spotify - https://tmt.ph/spotifyApple Podcasts - https://tmt.ph/applepodcastsAmazon Music - https://tmt.ph/amazonmusicDeezer: https://tmt.ph/deezerStitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tunein#TheManilaTimes#KeepUpWithTheTimesSubscribe to The Manila Times Channel - https://tmt.ph/YTSubscribeVisit our website at https://www.manilatimes.netFollow us:Facebook - https://tmt.ph/facebookInstagram - https://tmt.ph/instagramTwitter - https://tmt.ph/twitterDailyMotion - https://tmt.ph/dailymotioSubscribe to our Digital Edition - https://tmt.ph/digitalSign up to our newsletters: https://tmt.ph/newslettersCheck out our Podcasts:Spotify - https://tmt.ph/spotifyApple Podcasts - https://tmt.ph/applepodcastsAmazon Music - https://tmt.ph/amazonmusicDeezer: https://tmt.ph/deezerStitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tunein#TheManilaTimes#KeepUpWithTheTimes Hosted on Acast. See acast.com/privacy for more information.

Guest Juliana Barros Lima Panelist Richard Littauer Show Notes In this episode of Sustain, Richard Littauer talks with Juliana (Jules) Barros Lima, a full-stack developer and marketing director at Associação Python Brasil. They explore Jules' involvement in organizing and supporting Python events across Brazil, including her work with PyLadies Recife and Python Brasil. The conversation dives into the challenges of fostering diversity and inclusion in open-source communities, touching on Jules' "atomic diversity" framework for engaging local, regional, and national groups. They also discuss the impact of the pandemic on the Python community, the importance of mentorship, and the role of diverse organizing teams in creating codes of conduct that are empathetic and effective. Jules emphasizes the significance of leadership development, community collaboration, and stepping out of comfort zones to strengthen open-source communities globally. Download now to hear more! [00:01:57] Jules gives an overview of the Associação Python Brasil, what they do, and the challenges of managing a large community. [00:03:39] Jules discusses recent events organized and supported by the association and mentions that Python Brasil 2024 will be held in Rio de Janeiro and expected to have at least 300-500 attendees. [00:04:49] Jules discusses the importance of recognizing different regions' unique cultural and economic situations within Brazil. [00:06:31] We learn about the importance of subgroups and identity-based communities like PyLadies, and Jules shares insights from a talk given at PyCon US about amplifying diversity within Python communities and introduces the concept of “atomic diversity.” [00:11:43] Jules highlights how the pandemic impacted Brazil's Python community and discusses efforts to rebuild the community through open source tools and events. [00:14:07] Richard asks about how Brazil's Python community fits within the larger global context and how Brazilian developers can bridge these gaps. Jules mentions that the community is still recovering and growing, the challenges with language barriers, and emphasizes the significance of maintaining open discussions and using GitHub. [00:17:12] Richard and Jules discuss the importance of having diverse organizing teams and codes of conduct (COCs). [00:23:03] Jules offers insights into the organizational challenges faced in building inclusive events and communities. One key takeaway is the importance of engaging and listening to minority groups, such as PyLadies and Rails Girls, and the need for mentorship to help build leadership within underrepresented communities. [00:26:52] Jules stresses that community work is about giving back to the people and organizations that helped individuals grow. [00:31:32] Jules shares strategies to foster new leadership by giving people manageable tasks and responsibilities to build confidence, engaging the community through social media, storytelling, and the need for cross-community collaboration. [00:36:00] Find out where you can follow Jules online. Spotlight [00:36:39] Richard's spotlight is ‘cat' Command. [00:37:08] Jules's spotlight is the project, Querido Diário (Dear Diary). Links SustainOSS (https://sustainoss.org/) podcast@sustainoss.org (mailto:podcast@sustainoss.org) richard@sustainoss.org (mailto:richard@sustainoss.org) SustainOSS Discourse (https://discourse.sustainoss.org/) SustainOSS Mastodon (https://mastodon.social/tags/sustainoss) Open Collective-SustainOSS (Contribute) (https://opencollective.com/sustainoss) Richard Littauer Socials (https://www.burntfen.com/2023-05-30/socials) Juliana (Jules) Barros Lima Website (https://bento.me/julesbrlm) Python Brasil 2024 (https://2024.pythonbrasil.org.br/) Associação Python Brasil (https://apyb.python.org.br/index.html) APyB (Python Brasil Association) (https://apyb.python.org.br/) APyB Tarefas (Tasks) (https://github.com/apyb/tarefas) APyB Comunidade (Discussions) (https://github.com/apyb/comunidade/discussions) PyLadies Recife (https://recife.pyladies.com/) PyLadies (https://pyladies.com/) Rails Girls (https://railsgirls.com/) Querido Diário (https://docs.queridodiario.ok.org.br/pt-br/latest/) Credits Produced by Richard Littauer (https://www.burntfen.com/) Edited by Paul M. Bahr at Peachtree Sound (https://www.peachtreesound.com/) Show notes by DeAnn Bahr Peachtree Sound (https://www.peachtreesound.com/) Special Guest: Juliana Barros Lima.

Nach einer viel zu langen Pause melden wir uns mit einer neuen Folge zurück. In dieser begrüßt Luis mit Andreas Schuler unseren Schweizer Experten, der viel Positives über den Auftritt seiner Ex-Springerkollegen beim Sommer-Grand-Prix in Rasnov zu berichten hat. Abseits einer überzeugenden italienischen Frauen-Mannschaft um Doppelsiegerin Lara Malsiner rätseln sie aber, welche Lehren sie aus diesem Wochenende ziehen soll. Verstärkt wird das Kopfzerbrechen von den stark besetzten COCs, die im Sommer parallel zum Sommer-Grand-Prix stattfinden. Wie wir diese Entwicklung finden, erfahrt ihr ebenso welche deutsche Skispringerin im Winter nicht an Wettkämpfen teilnehmen wird und, was am kommenden Wochenende alles ansteht. Foto: Ski ...Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten. kostenlos-hosten.de ist ein Produkt der Podcastbude.Gern unterstützen wir dich bei deiner Podcast-Produktion.

Nach einer viel zu langen Pause melden wir uns mit einer neuen Folge zurück. In dieser begrüßt Luis mit Andreas Schuler unseren Schweizer Experten, der viel Positives über den Auftritt seiner Ex-Springerkollegen beim Sommer-Grand-Prix in Rasnov zu berichten hat. Abseits einer überzeugenden italienischen Frauen-Mannschaft um Doppelsiegerin Lara Malsiner rätseln sie aber, welche Lehren sie aus diesem Wochenende ziehen soll. Verstärkt wird das Kopfzerbrechen von den stark besetzten COCs, die im Sommer parallel zum Sommer-Grand-Prix stattfinden. Wie wir diese Entwicklung finden, erfahrt ihr ebenso welche deutsche Skispringerin im Winter nicht an Wettkämpfen teilnehmen wird und, was am kommenden Wochenende alles ansteht. Foto: Ski ...Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten. kostenlos-hosten.de ist ein Produkt der Podcastbude.Gern unterstützen wir dich bei deiner Podcast-Produktion.

Nach einer viel zu langen Pause melden wir uns mit einer neuen Folge zurück. In dieser begrüßt Luis mit Andreas Schuler unseren Schweizer Experten, der viel Positives über den Auftritt seiner Ex-Springerkollegen beim Sommer-Grand-Prix in Rasnov zu berichten hat. Abseits einer überzeugenden italienischen Frauen-Mannschaft um Doppelsiegerin Lara Malsiner rätseln sie aber, welche Lehren sie aus diesem Wochenende ziehen soll. Verstärkt wird das Kopfzerbrechen von den stark besetzten COCs, die im Sommer parallel zum Sommer-Grand-Prix stattfinden. Wie wir diese Entwicklung finden, erfahrt ihr ebenso welche deutsche Skispringerin im Winter nicht an Wettkämpfen teilnehmen wird und, was am kommenden Wochenende alles ansteht. Foto: Ski ...Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten. kostenlos-hosten.de ist ein Produkt der Podcastbude.Gern unterstützen wir dich bei deiner Podcast-Produktion.

Nach einer viel zu langen Pause melden wir uns mit einer neuen Folge zurück. In dieser begrüßt Luis mit Andreas Schuler unseren Schweizer Experten, der viel Positives über den Auftritt seiner Ex-Springerkollegen beim Sommer-Grand-Prix in Rasnov zu berichten hat. Abseits einer überzeugenden italienischen Frauen-Mannschaft um Doppelsiegerin Lara Malsiner rätseln sie aber, welche Lehren sie aus diesem Wochenende ziehen soll. Verstärkt wird das Kopfzerbrechen von den stark besetzten COCs, die im Sommer parallel zum Sommer-Grand-Prix stattfinden. Wie wir diese Entwicklung finden, erfahrt ihr ebenso welche deutsche Skispringerin im Winter nicht an Wettkämpfen teilnehmen wird und, was am kommenden Wochenende alles ansteht. Foto: Ski Rasnov Flugshow in den Sozialen Netzwerken Flugshow auf Facebook Flugshow auf Instagram

Developer Relations has gone through quite a few changes over the last few years. In that vein, some people have found new skills in the ever-evolving world of tech. Along their journey, they moved away from DevRel, but still use those abilities in new ways. So, what is it like when you bounce from DevRel? Quote: “The message I'm sending to myself: I can't change the world until I change myself first” - Kendrick Lamar Checkouts Taylor Barnett-Torabi * Range (https://davidepstein.com/range/) by David Epstein Matt Broberg * ADRs (https://github.com/joelparkerhenderson/architecture-decision-record) or documenting decisions as a thing™ – Any Decision Record (formally Architectural) * If you're looking at PM roles, The Product Manager Interview (https://www.lewis-lin.com/the-product-manager-interview-lewis-lin) by Lewis C. Lin helped me get my footing Wesley Faulkner * How Teams Can Skip the Drama and Embrace Healthy Conflict with Amy Gallo | SXSW 2024 (https://www.youtube.com/watch?v=pwuwFyiaCdU) Jason Hand * DASH - 2024 (https://www.dashcon.io/) PJ Hagerty * Frank Turner's latest album - Undefeated (https://combine.fm/spotify/album/5htcBxqWfEWaZ7CCETXcH9) * Gary Clark Jr - JPEG RAW (https://combine.fm/spotify/album/09XurHGqbBgvj7SH96UbPV) * Geeky Jerseys (https://www.geekyjerseys.com/) Mary Thengvall * The Humans (https://amzn.to/3y3r5w1) by Matt Haig * Contributor Covenant (https://www.contributor-covenant.org/) code of conduct - they're working on v3 of the code of conduct and want feedback on how community builders have implemented CoCs in the past. Take the survey to help out! (https://docs.google.com/forms/d/e/1FAIpQLSdf3QE5n5ILH7Fq1nNSECwUFnfYYOwQw4A_zYik43CGVrdfcQ/viewform) Photo by Mantas Hesthaven on Unsplash Enjoy the podcast? Please take a few moments to leave us a review on iTunes (https://itunes.apple.com/us/podcast/community-pulse/id1218368182?mt=2) and follow us on Spotify (https://open.spotify.com/show/3I7g5W9fMSgpWu38zZMjet?si=eb528c7de12b4d7a&nd=1&dlsi=b0c85248dabc48ce), or leave a review on one of the other many podcasting sites that we're on! Your support means a lot to us and helps us continue to produce episodes every month. Like all things Community, this too takes a village. Special Guests: Matt Broberg and Taylor Barnett-Torabi.

In this episode Cody first talks with Taylor from Bolton about the COCs rapid rehousing program. Then Cody talks with Sheriff Riewestahl and Katrina from the Eau Claire Sheriffs Department on Kids and Cops program.If you or someone you know is affected by domestic violence and or sexual assault, we encourage you to call our 24/7 confidential hotline at 715-834-9578 or email us at director@boltonrefuge.orgSupport the show

In this episode, Kev, Jacob, and Val welcome Edward onto the show to talk about how he went running Varuna at a recent two day tournament in Canberra!   Edward's Lists aQZ2YXJ1bmETMjMwNDExIFNxdWFsbyBIQyB2MoEsAgEIARABAQACJAEBAAMPAQEABCUBAQAFJQEBAAaExgEIAAeExgEIAAiExgEFAAIJAQEBCgACAQEBAAMBAQYABAEBCQAFAQEFAAYBAQQAB4S5AQQACAoBAgAJhMABAwA= aQZ2YXJ1bmETMjMwMzE1IEN1dCBhYm92ZSB2MoEsAgEGAQwBAgACEwEBAAMTAQEABIOnAQIABYTGAQgABoTGAQUAAgsBAQEBAAIBAQEAAwEBCQAEAQEFAAUBAQQABoS5AQQABw8BAQAIJQEBAAklAQEACiQBAQALhMABAwA=   Kev's Lists gZQPcmFtYWgtdGFza2ZvcmNlEkRvdWJsZSBNYWdnaWUgV0lQIIEsAgEMAYE1AQMAAoNRAQEAA4E1AQIABIE7AQMABYSBAZCoAAaGIgEDAAeBLQEBAAiBOgEBAAmBTQEBAAqBTQEBAAuBLQELAAyBPgEBAAIBATIBAQA= gZQPcmFtYWgtdGFza2ZvcmNlEUFuemFjIGN1cCBtaXNzaWxlgSwCAQkBgS0BAQACgS0BEwADgS0BCAAEgS0BBwAFgTEBBAAGhSMBAwAHhSEBBQAIgTsBAwAJg1EBAQACBgGEgQGQqAACgT4BAQADgT4BAQAEgT0BAQAFhiIBAwAGgTcBBAA=   Jacob's Lists gTEHdGFydGFyeQcgVEFLIENIgSwCAQoBhGYBBgACgOUBBAADgOoBAgAEhHABCAAFgP8BAQAGgQABAwAHhGYBBAAIgQkBAgAJgOUBAQAKgPABAgACBQGEgQGQqAACgQEBAQADgOMBAQAEgOMBCAAFhGYBBQA= gTEHdGFydGFyeRBGcm9udGxpbmUgVEFLIFYygSwCAQoBhHABCAACgOoBAgADhHABBwAEhGYBBQAFgQEBAQAGgQEBAQAHgOUBBAAIgPEBAQAJhGYBBgAKgPABAgACBQGA5QECAAKEZgEFAAOA4wEIAASA4wEBAAWA4wEHAA==   TIMESTAMPS 00:00:00 - 00:44:35: Catch up 00:44:35 - 00:53:17: Announcements and events 00:53:17 - 01:18:47: Edward's lists 01:18:47 - 01:30:20: Kevin's lists 01:30:20 - 01:45:14: Jacob's lists 01:45:14 - 02:11:19: Round 1  02:11:19 - 02:45:30: Round 2 02:45:30 - 03:11:36: Round 3 03:11:36 - 04:07:35: Round 4 and final thoughts **APRIL CHALLENGE - THE GOOD OLD DAYS** For the month of April we want our listeners to jump in their time machines, back to the (debatable) good old days of ITS seasons past and play an older mission.  Pick from any of the official missions of the past, be they from ITS seasons or past global campaigns.  For all you newer players, experience the highs and lows of TIC-TAC-TOE and for older players introduce newer players to the joys of the XenoTech.  We'd love to read your battle reports and what your thoughts are on the missions of old. Just make sure you tell us the mission you played! As always, send in your reports and analysis to us at lossoflieutenant@gmail.com  A random winner will be chosen at the end of the month to win a blister of their choice from Toy Soldier Imports!   **Q2 Hobby Challenge - Mission Received** Are you also bored of the current mission line up? Want to flex those creative muscles and design a new mission to torture the LoL crew? Well this is your chance, as for the second quarter of 2023, we want you to design us some new missions! Send us your ideas for new missions, ensuring we know where to put everything, how to deploy, what the objectives are and any other special rules.  Please stick to the format of presenting missions in the typical ITS format, as it will help us and the community understand how to play your missions.  Extra points if you can tell us how any play testing went! Send your submission to lossoflieutenant@gmail.com At the end of the quarter, we will select our favourites give them an IRL test play! A random entry will win a small box set of their choice from Toy Soldier Imports! Good luck!   Melbourne Wargaming Incorporated - ITS League! When: 1 May - 1 July 2023 Where: Melbourne and Victoria What: Four round ITS league, taking place over the course of 8 weeks. 300pts, you can change your list between rounds, but your army is fixed. Missions will be randomly generated at the start of each round.  Cost: $15 for the league but you must be a member of MWI to enter (membership costs are $10 until 1st October) Additional Info: Event page on fbk and discord with link to sign up and payment. I will do my best to pair players for ease of travel, but also give players the opportunity to play people they haven't played before. All experience levels are welcome! Link to VIC Discord  https://discord.gg/qq2ZZcaZC5 Link to fbk event  https://fb.me/e/Kzz816ZK   Burn City Brawl 2023 When: 5-6 August 2023 Where: Flemington and Kensington Bowls Club Cost: $70 if purchased before the end of May, when it goes up to $75. Members of MWI will get an additional $5 off :)  What: 1. Cryogenics 2. Capture and Protect 3. Frontline 4. Supplies 5. Decapitation Link to fbk event https://fb.me/e/8I8lnPuat Link to registration form https://forms.gle/gxAqJrM84f1UH6js9   If you'd like to become a patreon, sign up to become one of our valued CoCs and listen LIVE to our recordings and help keep us on track! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at:  https://discord.gg/XmUDEky5Pg   Thanks for listening!

Join Jacob, Kev, and Val as they break down the recent Army update and the new and improved Bakunin Sectoral!   The crew also go over the recent challenge entries and talk about their favourites!   TIMESTAMPS 00:00:00 - 00:31:40: Catch up and recent games 00:31:40 - 01:00:00: News and Announcements 01:00:00 - 01:49:00: Challenge recap 01:49:00 - 02:45:00: Nomads and Bakunin 02:45:00 - 03:09:40: O12 03:09:40 - 03:16:24 - Other updates   If you'd like to see the entries for the recent challenges, links to them are below: March Challenge https://docs.google.com/document/d/1XVFJTPOxLOAz8nRCk1hBAwCfvUaGnM21yJUwK9LKbDY/edit?usp=sharing   Q1 2023 Challenge https://docs.google.com/document/d/1nJVvXpxVnMm9_eOonaROZVPUWiVd2XhJomtjUvkCiCs/edit?usp=sharing   ***APRIL CHALLENGE ANNOUNCEMENT - THE GOOD OLD DAYS*** For the month of April we want our listeners to jump in their time machines, back to the (debatable) good old days of ITS seasons past and play an older mission.  Pick from any of the official missions of the past, be they from ITS seasons or past global campaigns.  For all you newer players, experience the highs and lows of TIC-TAC-TOE and for older players introduce newer players to the joys of the XenoTech.  We'd love to read your battle reports and what your thoughts are on the missions of old. Just make sure you tell us the mission you played! As always, send in your reports and analysis to us at lossoflieutenant@gmail.com  A random winner will be chosen at the end of the month to win a blister of their choice from Toy Soldier Imports!   ***Q2 Hobby Challenge - Mission Received*** Are you also bored of the current mission line up? Want to flex those creative muscles and design a new mission to torture the LoL crew? Well this is your chance, as for the second quarter of 2023, we want you to design us some new missions! Send us your ideas for new missions, ensuring we know where to put everything, how to deploy, what the objectives are and any other special rules.  Please stick to the format of presenting missions in the typical ITS format, as it will help us and the community understand how to play your missions.  Extra points if you can tell us how any play testing went! Send your submission to lossoflieutenant@gmail.com At the end of the quarter, we will select our favourites give them an IRL test play! A random entry will win a small box set of their choice from Toy Soldier Imports! Good luck!   Melbourne Wargaming Incorporated - ITS League! When: 1 May - 1 July 2023 Where: Melbourne and Victoria What: Four round ITS league, taking place over the course of 8 weeks. 300pts, you can change your list between rounds, but your army is fixed. Missions will be randomly generated at the start of each round.  Cost: $15 for the league but you must be a member of MWI to enter (membership costs are $10 until 1st October) Additional Info: Event page on fbk and discord with link to sign up and payment. I will do my best to pair players for ease of travel, but also give players the opportunity to play people they haven't played before. All experience levels are welcome!   ANZAC Cup! When: 15-16 April Where: Australian Defence Force Academy Gym.  What: 4 rounds, two saturday, two sunday to allow interstate people to attend Round 1 will begin 1200 Saturday 300pts ITS No mods 2 Custom Missions Intent is to provide a ‘standard ITS experience' but with enough difference to be interesting Sign up to the Facebook Event on Infinity Australia, a link to the  ADF webpage is there with a link to payment. Tickets are $25 Contact Rob Wright on Infinity Australia or Inane Imp on Discord   Burn City Brawl 2023 When: 5-6 August 2023 Where: Flemington and Kensington Bowls Club Cost: $70 if purchased before the end of May, when it goes up to $75. Members of MWI will get an additional $5 off :)  What: 1. Cryogenics 2. Capture and Protect 3. Frontline 4. Supplies 5. Decapitation   All Systems Go - Infinity! What - 2 day ITS event in Geelong When - 23-24 Sept 2023 Missions Quad Control Supremacy Highly Classified Countermeasures Firefight Cost - $50 Where - 9/11 The Esplanade, North Shore There will be food and drinks available at the bar 30 PAX Tix available at the Throw The Dice!   If you'd like to become a patreon, sign up to become one of our valued CoCs and listen LIVE to our recordings and help keep us on track! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at:  https://discord.gg/XmUDEky5Pg   Thanks for listening!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.04.535590v1?rss=1 Authors: Liu, Y., Guo, J., Matoga, M., Korotkova, M., Jakobsson, P.-J., Aguzzi, A. Abstract: Oligodendrocyte-lineage cells of patients and animal models undergo prominent changes in various neurodegenerative disorders. This raises the question of how myelinating cells interact with neurodegenerative processes. Here, we investigated the role of oligodendrocyte precursor cells (NG2 glia) in prion infections. We found that NG2 glia were activated in prion-infected cerebellar organotypic cultured slices (COCS) and in brains of prion-inoculated mice. In both model systems, depletion of NG2 glia exacerbated prion-induced neurodegeneration and accelerated prion pathology, suggesting a protective effect for NG2 glia. Loss of NG2 glia unleashed a microglial reaction promoting the biosynthesis of prostaglandin E2 (PGE2), which augmented prion toxicity in HovS cells and COCS through binding to the EP1 and EP4 receptors. Pharmacological or genetic inhibition of PGE2 biosynthesis attenuated prion-induced neurodegeneration in COCS and mice, antagonized the enhanced neurodegeneration in NG2 glia-depleted COCS and brains after prion infection, and dampened the acceleration of prion disease in NG2 glia-depleted mice. These data unveil a non-cell-autonomous interaction involving NG2 glia and microglia in prion disease and suggest that PGE2 signaling may represent an actionable target against prion diseases. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This is a 2 part episode in which I discuss the very important topic of the dangers of birth control pills that you may not be aware of. Unfortunately, this information isn't readily available, which in my opinion is a crime. This is why I ask that you share this episode with as many female friends and family members you can, so we can spread this knowledge and hopefully prevent some nasty side effects from women who take the pill when there are other safer alternatives they can explore. In this episode I speak about: Alternative natural, safe, and effective remedies for those thinking about going on the pill for peri-menopause symptoms Contraceptive alternatives to the pill What to expect if you're thinking of coming off the pill and how to decrease post-pill symptoms … and a ton more. Mentioned in this episode: Equip prime protein - Click HERE to grab yours and use my code: TARA20 to get 20% off MegaSporeBiotic - Click HERE to grab this probiotic and use my practitioner code, which also gets you 10% off: TaraMegaSpore Linked studies: https://journals.lww.com/co-obgyn/Abstract/2021/12000/Oestrogen_component_of_COCs__have_we_finally_found.3.aspx#:~:text=Estetrol%20is%20the%20newest%20oestrogen,as%20compared%20to%20ethinyl%20estradiol PMID: 30658282 https://pubmed.ncbi.nlm.nih.gov/669152/ https://pubmed.ncbi.nlm.nih.gov/3567872/ https://pubmed.ncbi.nlm.nih.gov/2256527/ https://pubmed.ncbi.nlm.nih.gov/1500656/ https://pubmed.ncbi.nlm.nih.gov/27725646/ https://pubmed.ncbi.nlm.nih.gov/26919969/ https://pubmed.ncbi.nlm.nih.gov/28542115/ https://pubmed.ncbi.nlm.nih.gov/27182211/ https://pubmed.ncbi.nlm.nih.gov/9698126/ https://pubmed.ncbi.nlm.nih.gov/8549943/ https://pubmed.ncbi.nlm.nih.gov/1637902/ https://pubmed.ncbi.nlm.nih.gov/8030630/ https://pubmed.ncbi.nlm.nih.gov/8505183/ https://pubmed.ncbi.nlm.nih.gov/12198379/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967214/ https://pubmed.ncbi.nlm.nih.gov/28115639/ https://pubmed.ncbi.nlm.nih.gov/9805216/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173458/ https://bmjopen.bmj.com/content/11/6/e046607 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807507/ https://pubmed.ncbi.nlm.nih.gov/23852908/ https://www.webmd.com/skin-problems-and-treatments/hair-loss/hair-loss-oral-contraceptives https://pubmed.ncbi.nlm.nih.gov/2256527/ https://pubmed.ncbi.nlm.nih.gov/1637902/ https://pubmed.ncbi.nlm.nih.gov/25832993/ https://pubmed.ncbi.nlm.nih.gov/8549943/ https://pubmed.ncbi.nlm.nih.gov/8030630/ https://pubmed.ncbi.nlm.nih.gov/12198379/ https://womensmentalhealth.org/posts/hormonal-contraceptives-and-risk-for-depression-and-suicide/ https://pubmed.ncbi.nlm.nih.gov/28184328/ Thank you for joining me. If you enjoyed this episode I would be deeply grateful if you'd leave me a 5 star review, hit subscribe, and share this podcast with any friends or family you think would benefit. It's so important we share this information far and wide to help as many women as we can. Please feel free to tag me & connect with me on these social platforms: Instagram Tik Tok Facebook Group Make sure you're on my email list! Click HERE. If you're interested in finding out more about my women's hormone health restoring program, The Hormone Balance Solution, please click HERE.  

On this episode, Kev and Jacob discuss the missions for the upcoming ANZAC Cup being held in Canberra, Australia which is unusual for containing not one, but TWO custom missions. The guys also break down a recent event and the profiles we've seen for the soon to be released Bakunin action pack.   TIMESTAMPS: 00:00:00 - 00:27:47: Catch up and recent games 00:27:47 - 00:38:17: Challenges 00:38:17 - 01:15:57: Bakunin profiles 01:15:57 - 01:19:17: Upcoming events 01:19:17 - 01:39:17: Frontline 01:39:17 - 02:03:17: Sensor Field 02:03:17 - 02:47:17: Clighy Hassified 02:47:17 - 03:27:30: General thoughts on the line up and custom missions in competitive play   We also post every episode to YouTube where you can see our faces and photos we share during the cast! https://www.youtube.com/channel/UCjk4j-dnxXRfHTfcpMb2oDQ   ANZAC Cup! When: 15-16 April Where: Australian Defence Force Academy Gym.  What: 4 rounds, two saturday, two sunday to allow interstate people to attend Round 1 will begin 1200 Saturday 300pts ITS No mods 2 Custom Missions Intent is to provide a ‘standard ITS experience' but with enough difference to be interesting Full mission line up: 1. Frontline, ITS Season 14 pg 37-38 2. Sensor Field 2.0, https://docs.google.com/document/d/1LnK2i5MhFJJkz5NGl1L1nnRqozXEsazY1UVlVPcM-9c/edit 3. Clighly Hassified 2.0, (note this will appear in OTM as Highly Classified) https://docs.google.com/document/d/1jp0AAao7W_kq14xmXBu-64-Ie33WVCgjN9p7uP49kRg/edit#heading=h.ucxv03ok2ky4 4. Rescue, ITS Season 14 pg 53-54 Aiming for 32 people. Currently uncapped but venue DOES have size limits; so the earlier we can confirm numbers the better Sign up to the Facebook Event on Infinity Australia, a link to the  ADF webpage is there with a link to payment. Tickets are $25 Contact Rob Wright on Infinity Australia or Inane Imp on Discord   Burn City Brawl 2023 When: 5-6 August 2023 Where: Flemington and Kensington Bowls Club Cost: TBA What: 5 round ITS 14, hopefully Melbourne Satellite event https://fb.me/e/8I8lnPuat   Operation: Vine Cutter https://docs.google.com/document/d/1S_4bmBUULkeTLxnefTA5Y_fksWB7tqSbO-P5qELNE7A/edit?usp=sharing   MARCH CHALLENGE - You Only Need Ten Models Here in Melbourne, we recently wrapped up our Slow Grow League. It was a huge success, with many new players getting their teeth into N4 in a friendly, supportive environment, and was also a great excuse for veterans to coach new players and try out new armies. So, for the month of March, we want YOU to introduce new players and run your own introductory game of Infinity! This can be at your regular games night, a day or evening at your house, or even a full on slow grow/escalation style event! Whatever it is, we want it to be aimed squarely at new players, with the aim by the end of the month, you will have acquired new knowledge on what worked (and what didn't work) for introducing new players to the game. As always, send us in your experiences of running intro/demo games of N4 or Code One to us as a Google Doc to: lossoflieutenant@gmail.com A random winner will be selected at the end of the month to win a blister of their choice from the legends over at Toy Soldier Imports!   Q1 2023 Hobby Challenge  Newly Classified Are you a little bored of the current classifieds deck? Tired of pulling Nano Espionage and just opting for Secure HVT instead? Well, this is your chance to put your creative hat on, as for the first quarter of 2023, we want you to design us some new classifieds! Send us your ideas for new Classified cards, how they will work and your reasons for choosing them to us at lossoflieutenant@gmail.com you can send in one, or a whole deck if you like, additional brownie points awarded to those who design the cards and artwork themselves. At the end of the quarter, we will select our favourites to build a new classified deck for people to try out and play in their games! A random entry will win a small box set of their choice from Toy Soldier Imports! Good luck!   If you'd like to become a patreon, sign up to become one of our valued CoCs and listen LIVE to our recordings and help keep us on track! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at:  https://discord.gg/XmUDEky5Pg   Thanks for listening!

This is a 2 part episode in which I discuss the very important topic of the dangers of birth control pills that you may not be aware of. Unfortunately, this information isn't readily available, which in my opinion is a crime. This is why I ask that you share this episode with as many female friends and family members you can, so we can spread this knowledge and hopefully prevent some nasty side effects from women who take the pill when there are other safer alternatives they can explore. In this episode I speak about: The increased risk of blood clots and stroke in those taking the pill The negative impact of the pill on bone health, libido, metabolic health and more The adverse impact of the pill on mental health The impact of the pill on various nutrients in the body The long-term consequences of taking the pill on thyroid health The increased risk of certain cancers that can occur when on the pill The significant increased risk of inflammatory bowel disease when taking the pill, which has been known about since the 70's … and a ton more.   Linked studies: https://journals.lww.com/co-obgyn/Abstract/2021/12000/Oestrogen_component_of_COCs__have_we_finally_found.3.aspx#:~:text=Estetrol%20is%20the%20newest%20oestrogen,as%20compared%20to%20ethinyl%20estradiol PMID: 30658282 https://pubmed.ncbi.nlm.nih.gov/669152/ https://pubmed.ncbi.nlm.nih.gov/3567872/ https://pubmed.ncbi.nlm.nih.gov/2256527/ https://pubmed.ncbi.nlm.nih.gov/1500656/ https://pubmed.ncbi.nlm.nih.gov/27725646/ https://pubmed.ncbi.nlm.nih.gov/26919969/ https://pubmed.ncbi.nlm.nih.gov/28542115/ https://pubmed.ncbi.nlm.nih.gov/27182211/ https://pubmed.ncbi.nlm.nih.gov/9698126/ https://pubmed.ncbi.nlm.nih.gov/8549943/ https://pubmed.ncbi.nlm.nih.gov/1637902/ https://pubmed.ncbi.nlm.nih.gov/8030630/ https://pubmed.ncbi.nlm.nih.gov/8505183/ https://pubmed.ncbi.nlm.nih.gov/12198379/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967214/ https://pubmed.ncbi.nlm.nih.gov/28115639/ https://pubmed.ncbi.nlm.nih.gov/9805216/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173458/ https://bmjopen.bmj.com/content/11/6/e046607 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807507/ https://pubmed.ncbi.nlm.nih.gov/23852908/ https://www.webmd.com/skin-problems-and-treatments/hair-loss/hair-loss-oral-contraceptives https://pubmed.ncbi.nlm.nih.gov/2256527/ https://pubmed.ncbi.nlm.nih.gov/1637902/ https://pubmed.ncbi.nlm.nih.gov/25832993/ https://pubmed.ncbi.nlm.nih.gov/8549943/ https://pubmed.ncbi.nlm.nih.gov/8030630/ https://pubmed.ncbi.nlm.nih.gov/12198379/ https://womensmentalhealth.org/posts/hormonal-contraceptives-and-risk-for-depression-and-suicide/ https://pubmed.ncbi.nlm.nih.gov/28184328/   Mentioned in this episode: Equip prime protein - Click HERE to grab yours and use my code: TARA20 to get 20% off MegaSporeBiotic - Click HERE to grab this probiotic and use my practitioner code, which also gets you 10% off: TaraMegaSpore   Thank you for joining me. If you enjoyed this episode I would be deeply grateful if you'd leave me a 5 star review, hit subscribe, and share this podcast with any friends or family you think would benefit. It's so important we share this information far and wide to help as many women as we can. Please feel free to tag me & connect with me on these social platforms: Instagram Tik Tok Facebook Group Make sure you're on my email list! Click HERE. If you're interested in finding out more about my women's hormone health restoring program, The Hormone Balance Solution, please click HERE.

Hey folks!   Join Jacob, Kev, and Val on the latest episode as they discuss the under appreciated units in Infinity that you should be including in your next game! The gang also catch up to talk about the latest releases, news and rumours from CB, and announce the winner of last month's challenge and reveal the challenge for March!   TIMESTAMPS 00:00:00 - 01:08:50: Catch up, news and challenges 01:08:50 - 03:43:36: Main Segment   Upcoming events: Thunder Over Helheim 18 March 1st Reservoir Scout Hall Link to fbk event: https://fb.me/e/fjpaKi6bV Link to rego form: https://forms.gle/XWeoErTkRmC9Paqb9   ANZAC Cup! When: 15-16 April Where: Australian Defence Force Academy Gym.  What: 4 rounds, two saturday, two sunday to allow interstate people to attend Round 1 will begin 1200 Saturday 300pts ITS No mods 2 Custom Missions Intent is to provide a ‘standard ITS experience' but with enough difference to be interesting Full mission line up: 1. Frontline, ITS Season 14 pg 37-38 2. Sensor Field 2.0, 3. Clighly Hassified 2.0, (note this will appear in OTM as Highly Classified) 4. Rescue, ITS Season 14 pg 53-54 Aiming for 32 people. Currently uncapped but venue DOES have size limits; so the earlier we can confirm numbers the better Sign up to the Facebook Event on Infinity Australia, a link to the  ADF webpage is there with a link to payment. Tickets are $25 Contact Rob Wright on Infinity Australia or Inane Imp on Discord   Burn City Brawl 2023 When: 5-6 August 2023 Where: Flemington and Kensington Bowls Club Cost: TBA What: 5 round ITS 14, hopefully Melbourne Satellite event https://fb.me/e/8I8lnPuat   MARCH CHALLENGE - You Only Need Ten Models Here in Melbourne, we recently wrapped up our Slow Grow League. It was a huge success, with many new players getting their teeth into N4 in a friendly, supportive environment, and was also a great excuse for veterans to coach new players and try out new armies. So, for the month of March, we want YOU to introduce new players and run your own introductory game of Infinity! This can be at your regular games night, a day or evening at your house, or even a full on slow grow/escalation style event! Whatever it is, we want it to be aimed squarely at new players, with the aim by the end of the month, you will have acquired new knowledge on what worked (and what didn't work) for introducing new players to the game. As always, send us in your experiences of running intro/demo games of N4 or Code One to us as a Google Doc to: lossoflieutenant@gmail.com A random winner will be selected at the end of the month to win a blister of their choice from the legends over at Toy Soldier Imports!   Q1 2023 Hobby Challenge  Newly Classified Are you a little bored of the current classifieds deck? Tired of pulling Nano Espionage and just opting for Secure HVT instead? Well, this is your chance to put your creative hat on, as for the first quarter of 2023, we want you to design us some new classifieds! Send us your ideas for new Classified cards, how they will work and your reasons for choosing them to us at lossoflieutenant@gmail.com you can send in one, or a whole deck if you like, additional brownie points awarded to those who design the cards and artwork themselves. At the end of the quarter, we will select our favourites to build a new classified deck for people to try out and play in their games! A random entry will win a small box set of their choice from Toy Soldier Imports! Good luck!   If you'd like to become a patreon, sign up to become one of our valued CoCs! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at:  https://discord.gg/XmUDEky5Pg   Thanks for listening!  

Hey folks!   On this episode Jacob and Val are joined by Ivory to discuss his experience with the transition from Table Top Simulator Infinity to the real thing and his experience playing the arguably hipster choice of vanilla Pan Oceania at Cancon 2023   Timestamps Challenge Announcement: 0:00:00 - 00:02:25 Episode Start: 00:02:25 - 00:07:02 Hobby Catch Up: 00:07:02 - 00:13:00 Infinity News (Bakunin Leak): 00:13:00 - 00:23:40 Event Announcements: 00:23:40 - 00:29:09 Main Segment, Ivory Interview: 00:29:09 - 02:19:03   Melbourne Slow Grow Round 3 When: Sunday, 26th of February  Where: House of War, Ringwood, VIC Cost: $20 Tickets and information can be found on facebook here: https://www.facebook.com/events/5806580092728336   ANZAC Cup! When:15-16th of April. Where: Australian Defence Force Academy Gym.  Sign up to the Facebook Event on Infinity Australia. Check out the ADFWGA Webpage, sign ups and payment will (once posted) be via that page.    February Challenge - Mark It! Learning how to apply and defend against marker states in Infinity is a complicated process, it fundamentally changes the ARO mechanic and can require hours of practice to become competent.   However, it is also one of the most important and powerful skills in the game, and one every player must learn.   So, for the month of February we want you to play around with using or facing the various types of marker states in Infinity.   For reference these are: Camouflage (including mines and decoys) Impersonation (including from cybermask) Holoecho (from Holoprojector equipment)   These can be in the form of battle reports, in depth analysis, or tips and tricks you have picked up along your Infinity journey!   As always, send your reports into us as a Google Doc to: lossoflieutenant@gmail.com   A random winner will be selected at the end of February to win a blister of their choice from Toy Soldier Imports   Good luck Q1 2023 Hobby Challenge  Newly Classified Are you a little bored of the current classifieds deck? Tired of pulling Nano Espionage and just opting for Secure HVT instead? Well, this is your chance to put your creative hat on, as for the first quarter of 2023, we want you to design us some new classifieds!   Send us your ideas for new Classified cards, how they will work and your reasons for choosing them to us at lossoflieutenant@gmail.com you can send in one, or a whole deck if you like, additional brownie points awarded to those who design the cards and artwork themselves.   At the end of March, we will select our favourites to build a new classified deck for people to try out and play in their games!   A random entry will win a small box set of their choice from Toy Soldier Imports!   Good luck!   If you'd like to become a patreon, sign up to become one of our valued CoCs! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at:  https://discord.gg/XmUDEky5Pg   Thanks for listening!  

Hey folks!   On this episode Kev, Val, and Jacob are joined by Robert Cantrell to discuss his experience with Tohaa at Cancon 2023 and his general thoughts on where Infinity and Infinity events are at the moment   Timestamps 00:00:00 - 00:42:17: Introduction, recent games and March releases 00:42:17 - 03:27:36: Interview with Rob   Check out Rob's YouTube channel at: https://www.youtube.com/@R0bertShepherd   Check out VaulSC's hilarious YouTube videos here: https://www.youtube.com/@VaulSC   Melbourne Slow Grow Round 3 When: Sunday, 26th of February  Where: House of War, Ringwood, VIC Cost: $20 Tickets and information can be found on fbk here: https://www.facebook.com/events/5806580092728336   January Monthly Challenge - What's Cooler Than Being Cool? Simple one for January for everyone. We want you to play the newest ITS mission, Cryogenics and let us know what you think of it. This is also the final mission of Cancon, so those going along, if your brain isn't too fried by round five, we'd love to read your battle reports and what your thoughts are on the mission As always, send in your reports and analysis to us at lossoflieutenant@gmail.com  A random winner will be chosen at the end of the month to win a blister of their choice from Toy Soldier Imports! Good Luck!   Q1 2023 Hobby Challenge - Newly Classified Are you a little bored of the current classifieds deck? Tired of pulling Nano Espionage and just opting for Secure HVT instead? Well, this is your chance to put your creative hat on, as for the first quarter of 2023, we want you to design us some new classifieds! Send us your ideas for new Classified cards, how they will work and your reasons for choosing them to us at lossoflieutenant@gmail.com you can send in one, or a whole deck if you like, additional brownie points awarded to those who design the cards and artwork themselves. At the end of the quarter, we will select our favourites to build a new classified deck for people to try out and play in their games! A random entry will win a small box set of their choice from Toy Soldier Imports! Good luck!   If you'd like to become a patreon, sign up to become one of our valued CoCs! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at:  https://discord.gg/XmUDEky5Pg   Thanks for listening!

Hey folks!   Welcome to another edition of our short form series, Spotlight!   On this installment, Kevin chats to Danny from Melbourne about event preparation and tips for new players attending Cancon this weekend.   Danny is also an accomplished commission painter for a variety of systems. Check him out on his Youtube, Instagram and website below!   https://www.youtube.com/channel/UChfUHF61Phc4WKjk0dstulw https://www.instagram.com/danny.paints/ www.Dannypaints.com   If you'd like to become a patreon, sign up to become one of our valued CoCs! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at: https://discord.gg/XmUDEky5Pg   Thanks for listening!

Happy new year everyone!   On tonight's episode, Jacob, Kev, and Val discuss recent games and releases, announce the winners of the recent challenges and reveal the new monthly and quarterly challenges. We then dive into our listener list submissions for the upcoming Australian National Tournament, Cancon!   TIMESTAMPS 00:00:00 - 00:25:40 - Recent Games and Hobby 00:25:40 - 00:36:13 - Challenge winners and announcements 00:36:13 - 00:48:43 - Recent releases 00:48:43 – 01:03:43 – Aleph 01:03:43 – 01:18:43 – Morats 01:18:43 – 01:46:00 - Corregidor 01:46:00 – 02:09:00 – Shock Army and Aleph 02:09:00 – 02:24:00 – MO 02:24:00 – 02:37:00 – Tohaa 02:37:00 – 02:48:00 – JSA 02:48:00 – 02:57:30 – OSS 02:57:30 – 03:10:50 – Hassassins 03:10:50 – 03:21:55 – Corregidor 03:21:55 – 03:33:00 – Shas 03:33:00 – 03:49:37 – ISS (Val's lists)   Link to see all the lists are below. Let us know if we've missed any https://docs.google.com/spreadsheets/d/1e7Q789_YVnlhz7qnz-eXdLSJb6GKxvjKbKSUd-m1Va8/edit#gid=1240283565   January Monthly Challenge - What's Cooler Than Being Cool? Simple one for January for everyone. We want you to play the newest ITS mission, Cryogenics and let us know what you think of it. This is also the final mission of Cancon, so those going along, if your brain isn't too fried by round five, we'd love to read your battle reports and what your thoughts are on the mission As always, send in your reports and analysis to us at lossoflieutenant@gmail.com A random winner will be chosen at the end of the month to win a blister of their choice from Toy Soldier Imports! Good Luck!   Q1 2023 Hobby Challenge - Newly Classified Are you a little bored of the current classifieds deck? Tired of pulling Nano Espionage and just opting for Secure HVT instead? Well, this is your chance to put your creative hat on, as for the first quarter of 2023, we want you to design us some new classifieds! Send us your ideas for new Classified cards, how they will work and your reasons for choosing them to us at lossoflieutenant@gmail.com you can send in one, or a whole deck if you like, additional brownie points awarded to those who design the cards and artwork themselves. At the end of the quarter, we will select our favourites to build a new classified deck for people to try out and play in their games! A random entry will win a small box set of their choice from Toy Soldier Imports! Good luck!   If you'd like to become a patreon, sign up to become one of our valued CoCs! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at: https://discord.gg/XmUDEky5Pg   Thanks for listening!

The whole LoL crew get together to cover AMA questions submitted by our listeners and celebrate another great year of Infinity. December Challange - Now I Have A Machine Gun - Ho, Ho, Ho Use a profile with Booty and write about your experience. Send in your reports and analysis to lossoflieutenant@gmail.com A random winner will be chosen at the end of the month to win a blister of their choice! Q4 Challenge - ITS14 Extras Paint up a CSU, Bashi or Sensor bot by the end of the year to win a small box set. Send one before and up to four after pictures to lossoflieutenant@gmail.com If you'd like to become a patreon, sign up to become one of our valued CoCs! https://www.patreon.com/lossoflieutenant Join us on our friendly LoL Discord at: https://discord.gg/XmUDEky5Pg Thanks for listening!

La Fiscalía General de la República (FGR) informó este viernes del decomiso de unos 300 kilos de fentanilo, que fueron detectados en cocos de palmera que eran transportados en un camión con destino a la frontera con Estados Unidos.El diputado y líder nacional del Partido Revolucionario Institucional (PRI), Alejandro Moreno, dijo que lo pueden perseguir y amenazar, pero que su bancada votará en contra de la reforma electoral e incluso, emplazó a poner día y hora para debatirla.

Nick, Jacob,and Val (plus a bit of Kev) are joined by special guest Rob Cantrell to discuss the ins and outs of the upcoming 2 day infinity tournament at Cancon 2023 December Challange - Now I Have A Machine Gun - Ho, Ho, Ho Use a profile with Booty and write about your experience. Send in your reports and analysis to lossoflieutenant@gmail.com A random winner will be chosen at the end of the month to win a blister of their choice! Q4 Challenge - ITS14 Extras Paint up a CSU, Bashi or Sensor bot by the end of the year to win a small box set. Send one before and up to four after pictures to lossoflieutenant@gmail.com  If you'd like to become a patreon, sign up to become one of our valued CoCs! https://www.patreon.com/lossoflieutenant Join us on our friendly LoL Discord at: https://discord.gg/XmUDEky5Pg Thanks for listening!

Hey folks!   Join Jacob, Kev and Val as they discuss the recent studio update from CB as well as talk about recent games, make some announcements and read out listener emails!   This episode is part one of two, it was broken up because the whole recording was almost four hours and ain't nobody got time for that!   TIMESTAMPS 00:00:00 - Intro 00:23:00 - Studio Update 01:00:00 - Recent Games   Links to the announcements, tournaments and how to donate to Obyiscus' charity gaming stream are below!   November Monthly Challenge - Swiss Army Bot With ITS14 and the Tachimotos seasonal rule giving Sensor bots Marksmanship, Tactical Awareness AND ECM Hacker (-3), we'd love to hear from our listeners about how they've gone running these now very dangerous remotes! Send in your reports and analysis to us as a Google Doc to lossoflieutenant@gmail.com A random winner will be selected at the end of the month to win a blister of their choice from Toy Soldier Imports!   Q4 Hobby Challenge - ITS14 Extras Until the end of the year, we want you to paint up one of the ITS 14 extras. This can be a SecDet CSU, A Corsair Bashi Bazouk, or a Tachimotos equipped toolbox bot! To enter, send us one before and up to four after photos to us at lossoflieutenant@gmail.com We want it to be new for the challenge, so please do not share it on the socials before the end of the quarter. A random winner will be selected at the end of the month to win a small box set of their choice from Toy Soldier Imports!   Event Announcements   Slow Grow - Round 2 Nov 27th House of War, Ringwood 225pt, No Restrictions 32x48” tables Mission Line Up - Acquisition - Supremacy - Decapitation  Missions chosen due to their resemblance to the Direct Action Missions Tickets can be purchased via facebook or on the VIC Discord server. A link to the registration form will be posted in the show notes https://forms.gle/pJ71pNTF9xAxTr4u5   Road to Cancon  7Jan 2023 Seabrook Community Center 15 Truganina Ave, Seabrook VIC 3028 Missions are: Supplies Unmasking Cyrogenics Doors open at 9 Finish at 6 2 hour rounds Tickets can be purchased via facebook or on the VIC Discord server. A link to the registration form will be posted in the show notes Register at https://forms.gle/tMytBATyQQ8RS9Yx7   Cancon 2023 January 21st - 23rd Exhibition Park, Canberra 300 pts, No Restriction Mission Line Up Scenario 1: Acquisition Scenario 2: Unmasking Scenario 3: Supplies Scenario 4: Supremacy Scenario 5: Cryogenics Head on over to the Cancon website to sign up! A link to sign up will be posted in the show notes https://cgs.asn.au/cancon/cancon-tournaments/#Infinity-Nationals   Can'tCon 2023 - Can't go to CanCon then come to Can'tCon.  When: Saturday 28th Jan 2023 What: 4 rounds, 2 hrs per round, 300pts, 2 lists per player same army/sectorial. ITS extras are Double deck for veteran players (played in more than 5 ITS events) and Reinforced command for newer players (played less than 5 ITS events). Missions: Battleground, Cutthroat, Superiority, Uplink Centre. Location: Beyond Odyssey Games and Hobby, Balcatta, WA.  For more information head to the Western Australia Infinity Facebook page :)   Obyiscus 24hr extra life charity. Get on over and support! Link in the show notes https://www.extra-life.org/participant/Obyiscus https://www.facebook.com/donate/874358550225456 https://www.twitch.tv/obyiscus_hobby_and_gaming https://youtube.com/@obyiscushobbyandgaming   AMA - Ask us ANYTHINGGGGG Our end of year episode is gonna be Ask Us Anything! Your questions can be Infinity related or not, no question (within reason) is out of bounds. Wanna know our favourite ice cream, or favourite infinity profile, or our favourite episode? Just ask! Date: 13/12/22 Send us your questions to us at lossoflieutenant@gmail.com, facebook, or via the LoL Discord and we'll get them answered!   If you'd like to become a patreon, sign up to become one of our values CoCs! https://www.patreon.com/lossoflieutenant Join us on our friendly LoL Discord at: https://discord.gg/XmUDEky5Pg   Thanks for listening!    

Jacob, Kev, and Val continue their journey in part two where they break down the good, the bad and the ugly fireteams available to Ariadna and discuss how they would build lists in them.   TIMESTAMPS 00:00:00 - Caledonia 00:38:45 - MRRF 00:55:00 - USARF 01:22:00 - TAK 01:53:20 - Kosmo and Vanilla   November Monthly Challenge - Swiss Army Bot With ITS14 and the Tachimotos seasonal rule giving Sensor bots Marksmanship, Tactical Awareness AND ECM Hacker (-3), we'd love to hear from our listeners about how they've gone running these now very dangerous remotes! Send in your reports and analysis to us as a Google Doc to lossoflieutenant@gmail.com A random winner will be selected at the end of the month to win a blister of their choice from Toy Soldier Imports!   Q4 Hobby Challenge - ITS14 Extras Until the end of the year, we want you to paint up one of the ITS 14 extras. This can be a SecDet CSU, A Corsair Bashi Bazouk, or a Tachimotos equipped toolbox bot! To enter, send us one before and up to four after photos to us at lossoflieutenant@gmail.com We want it to be new for the challenge, so please do not share it on the socials before the end of the quarter. A random winner will be selected at the end of the month to win a small box set of their choice from Toy Soldier Imports!   AMA - Ask us ANYTHINGGGGG Our end of year episode is gonna be Ask Us Anything! Your questions can be Infinity related or not, no question (within reason) is out of bounds. Wanna know our favourite ice cream, or favourite infinity profile, or our favourite episode? Just ask! Date: 13/12/22 Send us your questions to us at lossoflieutenant@gmail.com, facebook, or via the LoL Discord and we'll get them answered!   If you'd like to become a patreon, sign up to become one of our values CoCs! https://www.patreon.com/lossoflieutenant Join us on our friendly LoL Discord at: https://discord.gg/XmUDEky5Pg   Thanks for listening!      

Jacob, Kev and Val discuss the Direct Action missions in ITS14 and recap a recent very successful 150pts Slow Grow event in Melbourne.   Congratulations to Hugh who is our random winner for October for his great entry on Super Jump in the current season November Challenge - Swiss Army Bot.   Send in your reports and analysis of using the Toolbox Remote in your games to lossoflieutenant@gmail.com A random winner will be chosen at the end of the month to win a blister of their choice!   Q4 Challenge - ITS14 Extras Paint up a CSU, Bashi or Sensor bot by the end of the year to win a small box set. Send one before and up to four after pictures to lossoflieutenant@gmail.com   If you'd like to become a patreon, sign up to become one of our values CoCs! https://www.patreon.com/lossoflieutenant   Join us on our friendly LoL Discord at: https://discord.gg/XmUDEky5Pg   Thanks for listening!   Timestamps 00:00:00 Intro 00:46:40 Direct Action Missions 01:09:15 Slow Grow Round 1 02:01:04 Closing Thoughts

Hey folks!   We have a special treat for our listeners.    Our wandering Warcor Kevin is currently travelling around Europe, and was lucky enough to swing by the Corvus Belli studios in Spain for an exclusive interview with chief Warcor, Carlos Morales, better known as Koni.   The pair discuss a range of topics and answer questions posted on Discord by our Patreons (our loyal CoCs).   Huge thank you to Koni and the entire Corvus Belli team for taking time out of their busy scehdule to show me around and answer our questions, it was a very memorable experience.   If you would like to become a CoC (Chain of Command) subscribe to our Patreon at: https://www.patreon.com/lossoflieutenant   You can also join the conversation by joining our Discord at: https://discord.gg/XmUDEky5Pg   Now also available on YouTube - https://www.youtube.com/watch?v=2L0eUZGVRpg    Thanks to our Patreons who submitted questions for the chat, apologies if we didn't get through them all. Bob Fletcher Headchime Critposting Admin Wonna Kyle Bonderud Turbo Chainsaw Balls Pony Rider Sam Benson   Thanks for listening!

On the show today: 01:00 - Smoko chat...jobs described liked no other 04:17 - Jade needs your help  07:15 - Jay's no.1: The Rock 2000  10:41 - Complaints hotline - travel edition 14:18 - Come see us in Hamilton next week! 16:30 - Nicknames Vol. 17: the best nicknames yet  20:45 - F**k yeah its Friday    If ya reckon we're OK, don't forget to subscribe! Be a part of the team on Instagram, Facebook, and Tik Tok

Subscribe to The Manila Times Channel - https://tmt.ph/YTSubscribe Visit our website at https://www.manilatimes.net Follow us: Facebook - https://tmt.ph/facebook Instagram - https://tmt.ph/instagram Twitter - https://tmt.ph/twitter DailyMotion - https://tmt.ph/dailymotion Subscribe to our Digital Edition - https://tmt.ph/digital Check out our Podcasts: Spotify - https://tmt.ph/spotify Apple Podcasts - https://tmt.ph/applepodcasts Amazon Music - https://tmt.ph/amazonmusic Deezer: https://tmt.ph/deezer Stitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tuneinSoundcloud: https://tmt.ph/soundcloud #TheManilaTimes Hosted on Acast. See acast.com/privacy for more information.

KUWTT: Senate transfers COCs to House | May 23, 2022 Subscribe to The Manila Times Channel - https://tmt.ph/YTSubscribe Visit our website at https://www.manilatimes.net Follow us: Facebook - https://tmt.ph/facebook Instagram - https://tmt.ph/instagram Twitter - https://tmt.ph/twitter DailyMotion - https://tmt.ph/dailymotion Subscribe to our Digital Edition - https://tmt.ph/digital Check out our Podcasts: Spotify - https://tmt.ph/spotify Apple Podcasts - https://tmt.ph/applepodcasts Amazon Music - https://tmt.ph/amazonmusic Deezer: https://tmt.ph/deezer Stitcher: https://tmt.ph/stitcher Tune In: https://tmt.ph/tunein Soundcloud: https://tmt.ph/soundcloud #TheManilaTimes #KeepUpWithTheTimes Hosted on Acast. See acast.com/privacy for more information.

Pastor Stephen Broden, Exec. Director of Content of Character Series says the left has deliberately lied to the black community to use them as a hammer against the system. Tune in to find out why, and how COCS is equipping the black church to push back against the lies with truth and grace. https://www.contentofcharacterseries.com

SPOILER-FREE sa first part ng FUN-yetang episode 'to as Please Pause talks about Erik Matti and Michiko Yamomoto's On the Job: The Missing 8! Ang dami naming napag-usapan dito—politics, corruption, journalism, pati na rin Omega, Rolex, Breitling, and Panerai. Sama niyo na rin ang kakatapos lang na filing of COCs, the controversial girl group Playgirls, and the best K-dramas we do not know. Somehow lahat yan connected sa The Missing 8! After premiering in the 78th Venice International Film Festival, sana napanood niyo 'tong movie na ginawang series sa HBO Go. Kung hindi kami nagkakamali, pwede niyo siyang panoorin with the free trial na akala namin 1 month pero 7 days lang pala ata; hindi talaga namin alam. Anyway, nabalitaan niyo naman siguro na nanalo si John Arcilla ng Volpi Cup for Best Actor dito for his role as Sisoy Salas. If you've seen On the Job, this is a must watch. If you haven't seen On the Job yet, GESENG GESENG na, we highly recommend that you do! Follow us on Instagram, Facebook, and Twitter @pleasepauseph and tell someone about Please Pause! Luxurious beddings woven from 100% viscose made from bamboo? Linen and Homes! Just visit their shop at podlink.co/e50 and use the promo code PLEASEPAUSEPOD upon checkout to get 10% off your first purchase! Check out the PIPE Network Marketplace for exclusive deals and discounts! Just visit http://www.pipenetwork.co/marketplace/ and use the promo code PLEASEPAUSE Shopee, Lazada, or Amazon we can help you with your internet shopping needs! Just use the links below to get into their website or app and start shopping! Make sure to use our links to let them know you heard it from us! Shop on Shopee using the following link for special offers: https://shp.ee/seuaju2 Shop on Lazada using the following link for special offers: https://bit.ly/3mrkm4B Shop on Amazon using the following link for special offers: http://podlink.co/idx Thank you for supporting Please Pause!

Practice Bulletin #1114, Published July 2010 (Reaffirmed 2018) 1. Pelvic pain and infertility are characteristic. Severe dyspareunia and dyschezia are indicative of deeply infiltrative disease. 2. The etiology is unknown, but currently thought to be due to the implantation of endometrial glands and stromal cells outside the uterus within the peritoneal cavity due to retrograde menstruation 3. Histologic evaluation of a surgical specimen is the gold standard for diagnosis. Visualization of endometriotic lesions has a high false positive rate. The finding of an endometriomas on imaging studies can alone be highly predictive, though. 4. Excision of endometriosis can improve fertility rates, particularly with the excision of an endometrioma. 5. NSAIDs, COCs, GnRH analogues, and progestins are all great alternatives to surgery for managing endometriosis-related pain Show Notes Theme music by Evan Handyside

Pastor Stephen Broden, Exec. Director of Content of Character Series says the left has deliberately lied to the Black community to use them as a hammer against the system. Tune in to find out why, and how COCS is equipping the black church to push back against the lies with truth and grace.

CME credits: 0.25 Valid until: 31-08-2022 Claim your CME credit at https://reachmd.com/programs/cme/applying-clinical-trial-data-on-newer-cOcs-into-real-world-patient-care/12689/ The effort to reduce the estrogen concentration in combination oral contraceptives (COCs) and strike the right balance between efficacy and safety appears to be never-ending. However, a recently FDA-approved estetrol/drospirenone COC formulation offers some unique properties not seen in current COC formulations. Join us as Dr. Jeffrey Jensen and Dr. Lee Shulman discuss if this estetrol/drospirenone COC formulation will allow physicians to better address these efficacy and safety issues.

CME credits: 0.25 Valid until: 29-06-2022 Claim your CME credit at https://reachmd.com/programs/cme/applying-clinical-trial-data-on-newer-chcs-into-real-world-patient-care/12689/ The effort to reduce the estrogen concentration in combination oral contraceptives (COCs) and strike the right balance between efficacy and safety appears to be never-ending. However, a recently FDA-approved estetrol/drospirenone COC formulation offers some unique properties not seen in current COC formulations. Join us as Dr. Jeffrey Jensen and Dr. Lee Shulman discuss if this estetrol/drospirenone COC formulation will allow physicians to better address these efficacy and safety issues.

CME credits: 0.25 Valid until: 29-06-2022 Claim your CME credit at https://reachmd.com/programs/cme/applying-clinical-trial-data-on-newer-chcs-into-real-world-patient-care/12689/ The effort to reduce the estrogen concentration in combination oral contraceptives (COCs) and strike the right balance between efficacy and safety appears to be never-ending. However, a recently FDA-approved estetrol/drospirenone COC formulation offers some unique properties not seen in current COC formulations. Join us as Dr. Jeffrey Jensen and Dr. Lee Shulman discuss if this estetrol/drospirenone COC formulation will allow physicians to better address these efficacy and safety issues.

With the elections drawing near, alam na natin ang ilan sa mga maaasahan natin: nuisance candidates sa filing of COCs; LSS-inducing campaign jingles; at (aminin) bagong listahan ng mga taong i-a-unfollow mo sa social media. But these are the least of our worries. Politicians are going digital, and we should beware of fake news and disinformation. But what should we do instead of being worried and disillusioned? See omnystudio.com/listener for privacy information.

Practice Bulletin #101, Published January 2010 (Reaffirmed 2016) 1. Most COCs combine a progestin (i.e. synthetic progesterone) for contraceptive effects with 10-35 mcg of an estrogen (usually ethinyl estradiol) to stabilize the endometrium and reduce unwanted spotting 2. COCs are a safe bet for management of heavy menstrual bleeding. If patient responds to COCs, they are most cost-effective for the first year, then it's more effective to switch to a levonorgestrel intrauterine system 3. The levonorgestrel intrauterine systems work better than progestin-only pills (e.g. norethindrone acetate) to reduce heavy menstrual bleeding and patients report greater satisfaction. 4. DMPA and the progestin IUD can regulate the menstrual cycle over the long haul, but will initially increase the irregularity of bleeding. 5. Before prescribing any hormonal contraception, review the US Medical Eligibility Criteria for Contraceptive Use. Show Notes **Visit our friends at The Labor of Love Co. to send a pregnant person in your life a curated maternity or postpartum care package!** Wine pairing: 2018 Pinot Noir from Tres Palacios Theme music by Evan Handyside Logo design by JD Dotson (jddotson1@gmail.com)

Hey everyone! Welcome back to the Crazy Beeutiful Life and welcome to Bee's Estrogen Empire. Bee's Estrogen Empire are a subseries of the Crazy Beeutiful Life, dedicated to discussing topics on women's health and the health of people who menstruate. After using combined oral contraceptives (COCs) for the last ten years, I was shocked when I genuinely had no idea how they worked in my body. It appears I am not alone, experiencing a lack of information in a system that has build so much shame around periods and talking about them. I want to uncover the many questions about COC and give you a clear picture about what is going on so you can make an informed decision for your health. We can't cover COCs without talking about your cycle, so we touch on that as well. There are a TON of different resources in the CBL facebook group, so head on over there for all the things! Lots of Love, xxo. Bee. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

http://loosescrewsed.com Join us on discord! And check out the merch store! Colin is back in action anchoring Lave Radio. Now until the 26th, Elite is free on epic store, ARX store black friday discounts are live, 30% off select items, Next week, the Stygian and Midnight Black paint jobs will become available at 15% off. Speed Bowl IV https://forums.frontier.co.uk/threads/speedbowl-iv-new-grounds-21-22-november-3306-hypersonic-gravity-assisted-racing-is-back.556052/#post-8738740 Squad Update: LSN takes Thurston Ring… my precious… Cocs total war Slowing our expansion state In Game News: https://community.elitedangerous.com/ Hadrion Duval gets smacked down 9 NMLA terrorists identified among refugees in FED space A fed station has been hit by NMLA bombs Community Goals Both Succeed: But Tracks fails to be online enough to catch the wild acceleration. But but but, reward percentile changed to 75% The Tuesday stream was really great and I personally keep being so impressed by our CS team. Credit Balance Pass Incoming: Starting with mining; PWA fix probably won’t come until later Next up is combat, and so on down the line Also discussed on stream was memorials policy updates. Combat tutor night for beginners.

CPL, CPC, CPA, CPV, CPM und TKP – wem da nicht die Ohren schlackern, der ist schon voll angekommen im neudeutschen Digital-Sprech. Damit du beim nächsten IT-Talk nicht nur Bahnhof verstehst, haben Boris und Joel ein IT Lexikon für dich produziert. Darin bekommst du den auditiven Rundumschlag: von Wirtschaftskennzahlen über SaRS Metriken bis hin zu IT-Fachbegriffen. Du erfährst... 1)…wo die Unterschiede zwischen CIO, CTO, CAO und CDO liegen 2)…wie CLV und CAC im Verhältnis zueinander stehen 3)…wann dein Unternehmen sich für OPEX und wann für CAPEX entscheiden sollte 4)…was die relevanten Metriken von EBITDA sind

CPL, CPC, CPA, CPV, CPM und TKP – wem da nicht die Ohren schlackern, der ist schon voll angekommen im neudeutschen Digital-Sprech. Damit du beim nächsten IT-Talk nicht nur Bahnhof verstehst, haben Boris und Joel ein IT Lexikon für dich produziert. Darin bekommst du den auditiven Rundumschlag: von Wirtschaftskennzahlen über SaRS Metriken bis hin zu IT-Fachbegriffen. Du erfährst... 1)…wo die Unterschiede zwischen CIO, CTO, CAO und CDO liegen 2)…wie CLV und CAC im Verhältnis zueinander stehen 3)…wann dein Unternehmen sich für OPEX und wann für CAPEX entscheiden sollte 4)…was die relevanten Metriken von EBITDA sind

In the Resident Takeover episodes of Dermatology Weekly, Cutis Resident Corner columnists Drs. Daniel Mazori, Elisabeth Tracey, and Julie Croley have discussed lifestyle issues such as burnout in residents as well as management concerns such as treating hidradenitis suppurativa. In this episode, Dr. Mazori counts down the top downloaded Resident Takeovers in 2019. Psychodermatology, Episode 26: Drs. Tracey, Croley, and Mazori discussed the challenges of treating patients with both psychiatric and dermatologic diseases. They reviewed medical treatment modalities and considered when referral to a mental health professional is needed. Effective communication with patients, Episode 16: The three residents discussed how to set expectations with patients about therapeutic management and provided communication strategies for improving compliance with therapy and ensuring patients have the correct instructions. Being on-call as a dermatology resident, Episode 12: They talked about premade biopsy kits, tricks for achieving hemostasis in the hospital, portable electronic gadgets, and creative alternatives for basic items.  Prescribing combined OCs, Episode 20: In the most-accessed Resident Takeover of 2019, they talked about prescribing combined oral contraceptives (COCs). COCs have many uses in dermatology, but dermatologists often underutilize them and don’t feel comfortable prescribing them. They also reviewed the basics of prescribing COCs for dermatologic conditions. Hosts: Elizabeth Mechcatie, Terry Rudd Show notes by: Jason Orszt, Melissa Sears, Elizabeth Mechcatie You can find more of our podcasts at http://www.mdedge.com/podcasts Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgeDerm

Combined oral contraceptives (COCs) have many uses in dermatology, but dermatologists often underutilize COCs and don’t feel comfortable prescribing them. In this special resident takeover of the podcast, three dermatology residents — Dr. Daniel Mazori, Dr. Elisabeth Tracey, and Dr. Julie Croley — review the basics of prescribing COCs for dermatologic conditions. Beginning at 8:36, they discuss assessment of patient eligibility and selection of COCs, proper use of COCs, and management of risks and side effects. We also bring you the latest in dermatology news and research: 1. iPledge: Fetal exposure to isotretinoin continues  Although pregnancy-related adverse events have decreased, pregnancies, abortions, and fetal defects associated with isotretinoin exposure continue to be a problem. 2. Expert shares contact dermatitis trends Dr. Rajani Katta talks about what's happening in contact dermatitis, including an uptick in allergic reactions to essential oils contained in “all natural” products. Things you will learn in this episode: Acne is the main indication for COCs in dermatology, but other off-label uses include hidradenitis suppurativa, hirsutism, female pattern hair loss, and autoimmune progesterone dermatitis. When prescribing COCs, it is important to consider absolute and relative contraindications such as cardiovascular disease, postpartum status, women 35 years and older and smoking more than 15 cigarettes per day, migraine with aura, and history of diabetes for more than 20 years, plus others. Rule out pregnancy prior to starting COCs via a urine or serum pregnancy test. Dr. Croley points out, “A pelvic exam is not required to start combined oral contraceptives, as is sometimes thought by providers.” Monophasic formulations are considered first-line therapy. For patients who are concerned about symptoms associated with a hormone-free interval during treatment, choose a COC that does not include placebo pills, or encourage the patient to skip the placebo pills altogether and start the next pack earlier. Estrogen-related side effects are a consideration when prescribing COCs. “In general, the lowest possible dose of estrogen that is effective and tolerable should be prescribed,” Dr. Libby advises. Combined oral contraceptives can be started on any day of the patient’s menstrual cycle, but patients should be counseled to use backup contraception for 7 days if the COC is started more than 5 days after the first day of their most recent period. At least 3 months of therapy can be expected to evaluate the effectiveness of COCs for acne, potentially up to 6 months. Breakthrough bleeding is the most common side effect of COCs and can be minimized by taking the COC at about the same time every day and avoiding missed pills. If breakthrough bleeding persists after 3 cycles, consider increasing the estrogen dose or referring the patient to an obstetrician/gynecologist. Discuss the risk of venous thromboembolism with patients using the 3-6-9-12 model. Hosts: Elizabeth Mechcatie, Terry Rudd Guests: Daniel R. Mazori, MD (State University of New York Downstate Medical Center, Brooklyn); Elisabeth "Libby" Tracey, MD (Cleveland Clinic Foundation, Ohio); Julie Ann Amthor Croley, MD (The University of Texas Medical Branch at Galveston). Show notes by Alicia Sonners, Melissa Sears, and Elizabeth Mechcatie. You can find more of our podcasts at http://www.mdedge.com/podcasts      Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgeDerm  

JFH 24 Sven Paul Swanson NPCs VR Renegade CoCs by Rational Rise TV

Practice Bulletin #194, Polycystic Ovarian Syndrome, Published June 2018 We'll cover: - diagnosis and clinical workup - etiology - review of metabolic syndrome - clinical manifestations of PCOS - differential diagnosis - associated co-morbidities and risks - use of COCs to treat metabolic derangements and menstrual disorders - ovulation induction and other management options for infertility in PCOS ...and much more! SHOW NOTES This episode pairs nicely with the 2016 Wintner’s Collection Merlot from Sterling Vineyards Theme music by my main amigo, Evan Handyside

Mary and PJ join Jason to sync up on the recent episode that he hosted about Codes of Conduct. We cover a lot of ground: from the purpose that Codes of Conduct serve, to the fact that we agree to these standards in day-to-day life without realizing it, to the recent news stories about CoCs.

Mary and PJ join Jason to sync up on the recent episode that he hosted about Codes of Conduct. We cover a lot of ground: from the purpose that Codes of Conduct serve, to the fact that we agree to these standards in day-to-day life without realizing it, to the recent news stories about CoCs.

How the term open source was created, running FreeBSD on ThinkPad T530, Moving away from Windows, Unknown Giants, as well as OpenBSD and FreeDOS. This episode was brought to you by Headlines How I coined the term 'open source' (https://opensource.com/article/18/2/coining-term-open-source-software) In a few days, on February 3, the 20th anniversary of the introduction of the term "open source software" is upon us. As open source software grows in popularity and powers some of the most robust and important innovations of our time, we reflect on its rise to prominence. I am the originator of the term "open source software" and came up with it while executive director at Foresight Institute. Not a software developer like the rest, I thank Linux programmer Todd Anderson for supporting the term and proposing it to the group. This is my account of how I came up with it, how it was proposed, and the subsequent reactions. Of course, there are a number of accounts of the coining of the term, for example by Eric Raymond and Richard Stallman, yet this is mine, written on January 2, 2006. It has never been published, until today. The introduction of the term "open source software" was a deliberate effort to make this field of endeavor more understandable to newcomers and to business, which was viewed as necessary to its spread to a broader community of users. The problem with the main earlier label, "free software," was not its political connotations, but that—to newcomers—its seeming focus on price is distracting. A term was needed that focuses on the key issue of source code and that does not immediately confuse those new to the concept. The first term that came along at the right time and fulfilled these requirements was rapidly adopted: open source. This term had long been used in an "intelligence" (i.e., spying) context, but to my knowledge, use of the term with respect to software prior to 1998 has not been confirmed. The account below describes how the term open source software caught on and became the name of both an industry and a movement. Meetings on computer security In late 1997, weekly meetings were being held at Foresight Institute to discuss computer security. Foresight is a nonprofit think tank focused on nanotechnology and artificial intelligence, and software security is regarded as central to the reliability and security of both. We had identified free software as a promising approach to improving software security and reliability and were looking for ways to promote it. Interest in free software was starting to grow outside the programming community, and it was increasingly clear that an opportunity was coming to change the world. However, just how to do this was unclear, and we were groping for strategies. At these meetings, we discussed the need for a new term due to the confusion factor. The argument was as follows: those new to the term "free software" assume it is referring to the price. Oldtimers must then launch into an explanation, usually given as follows: "We mean free as in freedom, not free as in beer." At this point, a discussion on software has turned into one about the price of an alcoholic beverage. The problem was not that explaining the meaning is impossible—the problem was that the name for an important idea should not be so confusing to newcomers. A clearer term was needed. No political issues were raised regarding the free software term; the issue was its lack of clarity to those new to the concept. Releasing Netscape On February 2, 1998, Eric Raymond arrived on a visit to work with Netscape on the plan to release the browser code under a free-software-style license. We held a meeting that night at Foresight's office in Los Altos to strategize and refine our message. In addition to Eric and me, active participants included Brian Behlendorf, Michael Tiemann, Todd Anderson, Mark S. Miller, and Ka-Ping Yee. But at that meeting, the field was still described as free software or, by Brian, "source code available" software. While in town, Eric used Foresight as a base of operations. At one point during his visit, he was called to the phone to talk with a couple of Netscape legal and/or marketing staff. When he was finished, I asked to be put on the phone with them—one man and one woman, perhaps Mitchell Baker—so I could bring up the need for a new term. They agreed in principle immediately, but no specific term was agreed upon. Between meetings that week, I was still focused on the need for a better name and came up with the term "open source software." While not ideal, it struck me as good enough. I ran it by at least four others: Eric Drexler, Mark Miller, and Todd Anderson liked it, while a friend in marketing and public relations felt the term "open" had been overused and abused and believed we could do better. He was right in theory; however, I didn't have a better idea, so I thought I would try to go ahead and introduce it. In hindsight, I should have simply proposed it to Eric Raymond, but I didn't know him well at the time, so I took an indirect strategy instead. Todd had agreed strongly about the need for a new term and offered to assist in getting the term introduced. This was helpful because, as a non-programmer, my influence within the free software community was weak. My work in nanotechnology education at Foresight was a plus, but not enough for me to be taken very seriously on free software questions. As a Linux programmer, Todd would be listened to more closely. The key meeting Later that week, on February 5, 1998, a group was assembled at VA Research to brainstorm on strategy. Attending—in addition to Eric Raymond, Todd, and me—were Larry Augustin, Sam Ockman, and attending by phone, Jon "maddog" Hall. The primary topic was promotion strategy, especially which companies to approach. I said little, but was looking for an opportunity to introduce the proposed term. I felt that it wouldn't work for me to just blurt out, "All you technical people should start using my new term." Most of those attending didn't know me, and for all I knew, they might not even agree that a new term was greatly needed, or even somewhat desirable. Fortunately, Todd was on the ball. Instead of making an assertion that the community should use this specific new term, he did something less directive—a smart thing to do with this community of strong-willed individuals. He simply used the term in a sentence on another topic—just dropped it into the conversation to see what happened. I went on alert, hoping for a response, but there was none at first. The discussion continued on the original topic. It seemed only he and I had noticed the usage. Not so—memetic evolution was in action. A few minutes later, one of the others used the term, evidently without noticing, still discussing a topic other than terminology. Todd and I looked at each other out of the corners of our eyes to check: yes, we had both noticed what happened. I was excited—it might work! But I kept quiet: I still had low status in this group. Probably some were wondering why Eric had invited me at all. Toward the end of the meeting, the question of terminology was brought up explicitly, probably by Todd or Eric. Maddog mentioned "freely distributable" as an earlier term, and "cooperatively developed" as a newer term. Eric listed "free software," "open source," and "sourceware" as the main options. Todd advocated the "open source" model, and Eric endorsed this. I didn't say much, letting Todd and Eric pull the (loose, informal) consensus together around the open source name. It was clear that to most of those at the meeting, the name change was not the most important thing discussed there; a relatively minor issue. Only about 10% of my notes from this meeting are on the terminology question. But I was elated. These were some key leaders in the community, and they liked the new name, or at least didn't object. This was a very good sign. There was probably not much more I could do to help; Eric Raymond was far better positioned to spread the new meme, and he did. Bruce Perens signed on to the effort immediately, helping set up Opensource.org and playing a key role in spreading the new term. For the name to succeed, it was necessary, or at least highly desirable, that Tim O'Reilly agree and actively use it in his many projects on behalf of the community. Also helpful would be use of the term in the upcoming official release of the Netscape Navigator code. By late February, both O'Reilly & Associates and Netscape had started to use the term. Getting the name out After this, there was a period during which the term was promoted by Eric Raymond to the media, by Tim O'Reilly to business, and by both to the programming community. It seemed to spread very quickly. On April 7, 1998, Tim O'Reilly held a meeting of key leaders in the field. Announced in advance as the first "Freeware Summit," by April 14 it was referred to as the first "Open Source Summit." These months were extremely exciting for open source. Every week, it seemed, a new company announced plans to participate. Reading Slashdot became a necessity, even for those like me who were only peripherally involved. I strongly believe that the new term was helpful in enabling this rapid spread into business, which then enabled wider use by the public. A quick Google search indicates that "open source" appears more often than "free software," but there still is substantial use of the free software term, which remains useful and should be included when communicating with audiences who prefer it. A happy twinge When an early account of the terminology change written by Eric Raymond was posted on the Open Source Initiative website, I was listed as being at the VA brainstorming meeting, but not as the originator of the term. This was my own fault; I had neglected to tell Eric the details. My impulse was to let it pass and stay in the background, but Todd felt otherwise. He suggested to me that one day I would be glad to be known as the person who coined the name "open source software." He explained the situation to Eric, who promptly updated his site. Coming up with a phrase is a small contribution, but I admit to being grateful to those who remember to credit me with it. Every time I hear it, which is very often now, it gives me a little happy twinge. The big credit for persuading the community goes to Eric Raymond and Tim O'Reilly, who made it happen. Thanks to them for crediting me, and to Todd Anderson for his role throughout. The above is not a complete account of open source history; apologies to the many key players whose names do not appear. Those seeking a more complete account should refer to the links in this article and elsewhere on the net. FreeBSD on a Laptop - A guide to a fully functional installation of FreeBSD on a ThinkPad T530 (https://www.c0ffee.net/blog/freebsd-on-a-laptop) As I stated my previous post, I recently dug up my old ThinkPad T530 after the embarrassing stream of OS X security bugs this month. Although this ThinkPad ran Gentoo faithfully during my time in graduate school at Clemson, these days I'd much rather spend time my wife and baby than fighting with emerge and USE flags. FreeBSD has always been my OS of choice, and laptop support seems to be much better than it was a few years ago. In this guide, I'll show you the tweaks I made to wrestle FreeBSD into a decent experience on a laptop. Unlike my usual posts, this time I'm going to assume you're already pretty familiar with FreeBSD. If you're a layman looking for your first BSD-based desktop, I highly recommend checking out TrueOS (previously PC-BSD): they've basically taken FreeBSD and packaged it with all the latest drivers, along with a user-friendly installer and custom desktop environment out of the box. TrueOS is an awesome project–the only reason I don't use it is because I'm old, grumpy, and persnickety about having my operating system just so. Anyway, if you'd still like to take the plunge, read on. Keep in mind, I'm using a ThinkPad T530, but other ThinkPads of the same generation should be similarly compatible. Here's what you'll get: Decent battery life (8-9 hours with a new 9-cell battery) UEFI boot and full-disk encryption WiFi (Intel Ultimate-N 6300) Ethernet (Intel PRO/1000) Screen brightness adjustment Suspend/Resume on lid close (make sure to disable TPM in BIOS) Audio (Realtek ALC269 HDA, speakers and headphone jack) Keyboard multimedia buttons Touchpad/Trackpoint Graphics Acceleration (with integrated Intel graphics, NVIDIA card disabled in BIOS) What I haven't tested yet: Bluetooth Webcam Fingerprint reader SD Card slot Installation Power Saving Tweaks for Desktop Use X11 Fonts Login Manager: SLiM Desktop Environment: i3 Applications The LLVM Sanitizers stage accomplished (https://blog.netbsd.org/tnf/entry/the_llvm_sanitizers_stage_accomplished) I've managed to get the Memory Sanitizer to work for the elementary base system utilities, like ps(1), awk(1) and ksh(1). This means that the toolchain is ready for tests and improvements. I've iterated over the basesystem utilities and I looked for bugs, both in programs and in sanitizers. The number of detected bugs in the userland programs was low, there merely was one reading of an uninitialized variable in ps(1). A prebuilt LLVM toolchain I've prepared a prebuilt toolchain with Clang, LLVM, LLDB and compiler-rt for NetBSD/amd64. I prepared the toolchain on 8.99.12, however I have received reports that it works on other older releases. Link: llvm-clang-compilerrt-lldb-7.0.0beta_2018-01-24.tar.bz2 The archive has to be untarballed to /usr/local (however it might work to some extent in other paths). This toolchain contains a prebuilt tree of the LLVM projects from a snapshot of 7.0.0(svn). It is a pristine snapshot of HEAD with patches from pkgsrc-wip for llvm, clang, compiler-rt and lldb. Sanitizers Notable changes in sanitizers, all of them are in the context of NetBSD support. Added fstat(2) MSan interceptor. Support for kvm(3) interceptors in the common sanitizer code. Added devname(3) and devname_r(3) interceptors to the common sanitizer code. Added sysctl(3) familty of functions interceptors in the common sanitizer code. Added strlcpy(3)/strlcat(3) interceptors in the common sanitizer code. Added getgrouplist(3)/getgroupmembership(3) interceptors in the common sanitizer code. Correct ctype(3) interceptors in a code using Native Language Support. Correct tzset(3) interceptor in MSan. Correct localtime(3) interceptor in the common sanitizer code. Added paccept(2) interceptor to the common sanitizer code. Added access(2) and faccessat(2) interceptors to the common sanitizer code. Added acct(2) interceptor to the common sanitizer code. Added accept4(2) interceptor to the common sanitizer code. Added fgetln(3) interceptor to the common sanitizer code. Added interceptors for the pwcache(3)-style functions in the common sanitizer code. Added interceptors for the getprotoent(3)-style functions in the common sanitizer code. Added interceptors for the getnetent(3)-style functions in the common sanitizer code. Added interceptors for the fts(3)-style functions in the common sanitizer code. Added lstat(3) interceptor in MSan. Added strftime(3) interceptor in the common sanitizer code. Added strmode(3) interceptor in the common sanitizer code. Added interceptors for the regex(3)-style functions in the common sanitizer code. Disabled unwanted interceptor __sigsetjmp in TSan. Base system changes I've tidied up inclusion of the internal namespace.h header in libc. This has hidden the usage of public global symbol names of: strlcat -> _strlcat sysconf -> __sysconf closedir -> _closedir fparseln -> _fparseln kill -> _kill mkstemp -> _mkstemp reallocarr -> _reallocarr strcasecmp -> _strcasecmp strncasecmp -> _strncasecmp strptime -> _strptime strtok_r -> _strtok_r sysctl -> _sysctl dlopen -> __dlopen dlclose -> __dlclose dlsym -> __dlsym strlcpy -> _strlcpy fdopen -> _fdopen mmap -> _mmap strdup -> _strdup The purpose of these changes was to stop triggering interceptors recursively. Such interceptors lead to sanitization of internals of unprepared (not recompiled with sanitizers) prebuilt code. It's not trivial to sanitize libc's internals and the sanitizers are not designed to do so. This means that they are not a full replacement of Valgrind-like software, but a a supplement in the developer toolbox. Valgrind translates native code to a bytecode virtual machine, while sanitizers are designed to work with interceptors inside the pristine elementary libraries (libc, libm, librt, libpthread) and embed functionality into the executable's code. I've also reverted the vadvise(2) syscall removal, from the previous month. This caused a regression in legacy code recompiled against still supported compat layers. Newly compiled code will use a libc's stub of vadvise(2). I've also prepared a patch installing dedicated headers for sanitizers along with the base system GCC. It's still discussed and should land the sources soon. Future directions and goals Possible paths in random order: In the quartet of UBSan (Undefined Behavior Sanitizer), ASan (Address Sanitizer), TSan (Thread Sanitizer), MSan (Memory Sanitizer) we need to add the fifth basic sanitizer: LSan (Leak Sanitizer). The Leak Sanitizer (detector of memory leaks) demands a stable ptrace(2) interface for processes with multiple threads (unless we want to build a custom kernel interface). Integrate the sanitizers with the userland framework in order to ship with the native toolchain to users. Port sanitizers from LLVM to GCC. Allow to sanitize programs linked against userland libraries other than libc, librt, libm and libpthread; by a global option (like MKSANITIZER) producing a userland that is partially prebuilt with a desired sanitizer. This is required to run e.g. MSanitized programs against editline(3). So far, there is no Operating System distribution in existence with a native integration with sanitizers. There are 3rd party scripts for certain OSes to build a stack of software dependencies in order to validate a piece of software. Execute ATF tests with the userland rebuilt with supported flavors of sanitizers and catch regressions. Finish porting of modern linkers designed for large C++ software, such as GNU GOLD and LLVM LLD. Today the bottleneck with building the LLVM toolchain is a suboptimal linker GNU ld(1). I've decided to not open new battlefields and return now to porting LLDB and fixing ptrace(2). Plan for the next milestone Keep upstreaming a pile of local compiler-rt patches. Restore the LLDB support for traced programs with a single thread. Interview - Goran Mekic - meka@tilda.center (mailto:meka@tilda.center) / @meka_floss (https://twitter.com/meka_floss) CBSD website (https://bsdstore.ru) Jail and VM Manager *** News Roundup Finally Moving Away From Windows (https://www.manios.ca/blog/2018/01/finally-moving-away-from-windows/) Broken Window Thanks to a combination of some really impressive malware, bad clicking, and poor website choices, I had to blow away my Windows 10 installation. Not that it was Window's fault, but a piece of malware had infected my computer when I tried to download a long lost driver for an even longer lost RAID card for a server. A word of advice – the download you're looking for is never on an ad-infested forum in another language. In any case, I had been meaning to switch away from Windows soon. I didn't have my entire plan ready, but now was as good a time as any. My line of work requires me to maintain some form of Windows installation, so I decided to keep it in a VM rather than dual booting as I was developing code and not running any high-end visual stuff like games. My first thought was to install Arch or Gentoo Linux, but the last time I attempted a Gentoo installation it left me bootless. Not that there is anything wrong with Gentoo, it was probably my fault, but I like the idea of some sort of installer so I looked at rock-solid Debian. My dad had installed Debian on his sweet new cutting-edge Lenovo laptop he received recently from work. He often raves about his cool scripts and much more effective customized experience, but often complains about his hybrid GPU support as he has an Intel/Nvidia hybrid display adapter (he has finally resolved it and now boasts his 6 connected displays). I didn't want to install Windows again, but something didn't feel right about installing some flavour of Linux. Back at home I have a small collection of FreeBSD servers running in all sorts of jails and other physical hardware, with the exception of one Debian server which I had the hardest time dealing with (it would be FreeBSD too if 802.11ac support was there as it is acting as my WiFi/gateway/IDS/IPS). I loved my FreeBSD servers, and yes I will write posts about each one soon enough. I wanted that cleanliness and familiarity on my desktop as well (I really love the ports collection!). It's settled – I will run FreeBSD on my laptop. This also created a new rivalry with my father, which is not a bad thing either. Playing Devil's Advocate The first thing I needed to do was backup my Windows data. This was easy enough, just run a Windows Image Backup and it will- wait, what? Why isn't this working? I didn't want to fiddle with this too long because I didn't actually need an image just the data. I ended up just copying over the files to an external hard disk. Once that was done, I downloaded and verified the latest FreeBSD 11.1 RELEASE memstick image and flashed it to my trusty 8GB Verbatim USB stick. I've had this thing since 2007, it works great for being my re-writable “CD”. I booted it up and started the installation. I knew this installer pretty well as I had test-installed FreeBSD and OpenBSD in VMs when I was researching a Unix style replacement OS last year. In any case, I left most of the defaults (I didn't want to play with custom kernels right now) and I selected all packages. This downloaded them from the FreeBSD FTP server as I only had the memstick image. The installer finished and I was off to my first boot. Great! so far so good. FreeBSD loaded up and I did a ‘pkg upgrade' just to make sure that everything was up to date. Alright, time to get down to business. I needed nano. I just can't use vi, or just not yet. I don't care about being a vi-wizard, that's just too much effort for me. Anyway, just a ‘pkg install nano' and I had my editor. Next was obvious, I needed x11. XFCE was common, and there were plenty of tutorials out there. I wont bore you with those details, but it went something like ‘pkg install xfce' and I got all the dependencies. Don't forget to install SLiM to make it seamless. There are some configs in the .login I think. SLiM needs to be called once the boot drops you to the login so that you get SLiM's nice GUI login instead of the CLI login screen. Then SLiM passes you off to XFCE. I think I followed this and this. Awesome. Now that x11 is working, it's time to get all of my apps from Windows. Obviously, I can't get everything (ie. Visual Studio, Office). But in my Windows installation, I had chosen many open-source or cross-compiled apps as they either worked better or so that I was ready to move away from Windows at a moments notice. ‘pkg install firefox thunderbird hexchat pidgin gpa keepass owncloud-client transmission-qt5 veracrypt openvpn' were some immediate picks. There are a lot more that I downloaded later, but these are a few I use everyday. My laptop also has the same hybrid display adapter config that my dad's has, but I chose to only run Intel graphics, so dual screens are no problem for me. I'll add Nvidia support later, but it's not a priority. After I had imported my private keys and loaded my firefox and thunderbird settings, I wanted to get my Windows VM running right away as I was burning productive days at work fiddling with this. I had only two virtualisation options; qemu/kvm and bhyve. qemu/kvm wasn't available in pkg, and looked real dirty to compile, from FreeBSD's point of view. My dad is using qemu/kvm with virt-manager to manage all of his Windows/Unix VMs alike. I wanted that experience, but I also wanted packages that could be updated and I didn't want to mess up a compile. bhyve was a better choice. It was built-in, it was more compatible with Windows (from what I read), and this is a great step-by-step article for Windows 10 on FreeBSD 11 bhyve! I had already tried to get virt-manager to work with bhyve with no luck. I don't think libvirt connects with bhyve completely, or maybe my config is wrong. But I didn't have time to fiddle with it. I managed it all through command lines and that has worked perfectly so far. Well sorta, there was an issue installing SQL Server, and only SQL Server, on my Windows VM. This was due to a missing ‘sectorsize=512' setting on the disk parameter on the bhyve command line. That was only found after A LOT of digging because the SQL Server install didn't log the error properly. I eventually found out that SQL Server only likes one sector size of disks for the install and my virtual disk geometry was incorrect. Apps Apps Apps I installed Windows 10 on my bhyve VM and I got that all setup with the apps I needed for work. Mostly Office, Visual Studio, and vSphere for managing our server farm. Plus all of the annoying 3rd party VPN software (I'm looking at you Dell and Cisco). Alright, with the Windows VM done, I can now work at work and finish FreeBSD mostly during the nights. I still needed my remote files (I setup an ownCloud instance on a FreeNAS jail at home) so I setup the client. Now, normally on Windows I would come to work and connect to my home network using OpenVPN (again, I have a OpenVPN FreeNAS jail at home) and the ownCloud desktop would be able to handle changing DNS destination IPs Not on FreeBSD (and Linux too?). I ended up just configuring the ownCloud client to just connect to the home LAN IP for the ownCloud server and always connecting the OpenVPN to sync things. It kinda sucks, but at least it works. I left that running at home overnight to get a full sync (~130GB cloud sync, another reason I use it over Google or Microsoft). Once that was done I moved onto the fstab as I had another 1TB SSD in my laptop with other files. I messed around with fstab and my NFS shares to my FreeNAS at home, but took them out as they made the boot time so long when I wasn't at home. I would only mount them when my OpenVPN connected or manually. I really wanted to install SpaceFM, but it's only available as a package on Debian and their non-package install script doesn't work on FreeBSD (packages are named differently). I tried doing it manually, but it was too much work. As my dad was the one who introduced me to it, he still uses it as a use-case for his Debian setup. Instead I kept to the original PCManFM and it works just fine. I also loaded up my Bitcoin and Litecoin wallets and pointed them to the blockchain that I has used on Windows after their sync, they loaded perfectly and my balances were there. I kinda wish there was the Bitcoin-ABC full node Bitcoin Cash wallet package on FreeBSD, but I'm sure it will come out later. The rest is essentially just tweaks and making the environment more comfortable for me, and with most programs installed as packages I feel a lot better with upgrades and audit checking (‘pkg audit -F' is really helpful!). I will always hate Python, actually, I will always hate any app that has it's own package manager. I do miss the GUI GitHub tool on Windows. It was a really good-looking way to view all of my repos. The last thing (which is increasing it's priority every time I go to a social media site or YouTube) is fonts. My god I never thought it was such a problem, and UTF support is complicated. If anyone knows how to get all UTF characters to show up, please let me know. I'd really like Wikipedia articles to load perfectly (I followed this post and there are still some missing). There are some extra tweaks I followed here and here. Conclusion I successfully migrated from Windows 10 to FreeBSD 11.1 with minimal consequence. Shout out goes to the entire FreeBSD community. So many helpful people in there, and the forums are a great place to find tons of information. Also thanks to the ones who wrote the how-to articles I've referenced. I never would have gotten bhyve to work and I'd still probably be messing with my X config without them. I guess my take home from this is to not be afraid to make changes that may change how comfortable I am in an environment. I'm always open to comments and questions, please feel free to make them below. I purposefully didn't include too many technical things or commands in this article as I wanted to focus on the larger picture of the migration as a whole not the struggles of xorg.conf, but if you would like to see some of the configs or commands I used, let me know and I'll include some! TrueOS Rules of Conduct (https://www.trueos.org/rulesofconduct/) We believe code is truly agnostic and embrace inclusiveness regardless of a person's individual beliefs. As such we only ask the following when participating in TrueOS public events and digital forums: Treat each other with respect and professionalism. Leave personal and TrueOS unrelated conversations to other channels. In other words, it's all about the code. Users who feel the above rules have been violated in some way can register a complaint with abuse@trueos.org + Shorter than the BSD License (https://twitter.com/trueos/status/965994363070353413) + Positive response from the community (https://twitter.com/freebsdbytes/status/966567686015782912) I really like the @TrueOS Code of Conduct, unlike some other CoCs. It's short, clear and covers everything. Most #OpenSource projects are labour of love. Why do you need a something that reads like a legal contract? FreeBSD: The Unknown Giant (https://neomoevius.tumblr.com/post/171108458234/freebsd-the-unknown-giant) I decided to write this article as a gratitude for the recent fast answer of the FreeBSD/TrueOS community with my questions and doubts. I am impressed how fast and how they tried to help me about this operating system which I used in the past(2000-2007) but recently in 2017 I began to use it again. + A lot has changed in 10 years I was looking around the internet, trying to do some research about recent information about FreeBSD and other versions or an easy to use spins like PCBSD (now TrueOS) I used to be Windows/Mac user for so many years until 2014 when I decided to use Linux as my desktop OS just because I wanted to use something different. I always wanted to use unix or a unix-like operating system, nowadays my main objective is to learn more about these operating systems (Debian Linux, TrueOS or FreeBSD). FreeBSD has similarities with Linux, with two major differences in scope and licensing: FreeBSD maintains a complete operating system, i.e. the project delivers kernel, device drivers, userland utilities and documentation, as opposed to Linux delivering a kernel and drivers only and relying on third-parties for system software; and FreeBSD source code is generally released under a permissive BSD license as opposed to the copyleft GPL used by Linux.“ But why do I call FreeBSD “The Unknown Giant”?, because the code base of this operating system has been used by other companies to develop their own operating system for products like computers or also game consoles. + FreeBSD is used for storage appliances, firewalls, email scanners, network scanners, network security appliances, load balancers, video servers, and more So many people now will learn that not only “linux is everywhere” but also that “FreeBSD is everywhere too” By the way speaking about movies, Do you remember the movie “The Matrix”? FreeBSD was used to make the movie: “The photo-realistic surroundings generated by this method were incorporated into the bullet time scene, and linear interpolation filled in any gaps of the still images to produce a fluent dynamic motion; the computer-generated “lead in” and “lead out” slides were filled in between frames in sequence to get an illusion of orbiting the scene. Manex Visual Effects used a cluster farm running the Unix-like operating system FreeBSD to render many of the film's visual effects” + FreeBSD Press Release re: The Matrix (https://www.freebsd.org/news/press-rel-1.html) I hope that I gave a good reference, information and now so many people can understand why I am going to use just Debian Linux and FreeBSD(TrueOS) to do so many different stuff (music, 3d animation, video editing and text editing) instead use a Mac or Windows. + FreeBSD really is the unknown giant. OpenBSD and FreeDOS vs the hell in earth (https://steemit.com/openbsd/@npna/openbsd-and-freedos-vs-the-hell-in-earth) Yes sir, yes. Our family, composed until now by OpenBSD, Alpine Linux and Docker is rapidly growing. And yes, sir. Yes. All together we're fighting against your best friends, the infamous, the ugliest, the worst...the dudes called the privacy cannibals. Do you know what i mean, sure? We're working hard, no matter what time is it, no matter in what part in the world we are, no matter if we've no money. We perfectly know that you cannot do nothing against the true. And we're doing our best to expand our true, our doors are opened to all the good guys, there's a lot here but their brain was fucked by your shit tv, your fake news, your laws, etc etc etc. We're alive, we're here to fight against you. Tonight, yes it's a Friday night and we're working, we're ready to welcome with open arms an old guy, his experience will give us more power. Welcome to: FreeDOS But why we want to build a bootable usb stick with FreeDOS under our strong OpenBSD? The answer is as usual to fight against the privacy cannibals! More than one decade ago the old BIOS was silently replaced by the more capable and advanced UEFI, this is absolutely normal because of the pass of the years and exponencial grow of the power of our personal computers. UEFI is a complex system, it's like a standalone system operative with direct access to every component of our (yes, it's our not your!) machine. But...wait a moment...do you know how to use it? Do you ever know that it exist? And one more thing, it's secure? The answer to this question is totally insane, no, it's not secure. The idea is good, the company that started in theory is one of the most important in IT, it's Intel. The history is very large and obviously we're going to go very deep in it, but trust me UEFI and the various friend of him, like ME, TPM are insecure and closed source! Like the hell in earth. A FreeDOS bootable usb image under OpenBSD But let's start preparing our OpenBSD to put order in this chaos: $ mkdir -p freedos/stuff $ cd freedos/stuff $ wget https://www.ibiblio.org/pub/micro/pc-stuff/freedos/files/distributions/1.0/fdboot.img $ wget https://www.ibiblio.org/pub/micro/pc-stuff/freedos/files/dos/sys/sys-freedos-linux/sys-freedos-linux.zip $ wget https://download.lenovo.com/consumer/desktop/o35jy19usa_y900.exe $ wget http://145.130.102.57/domoticx/software/amiflasher/AFUDOS%20Flasher%205.05.04.7z Explanation in clear language as usual: create two directory, download the minimal boot disc image of FreeDOS, download Syslinux assembler MBR bootloaders, download the last Windows only UEFI update from Lenovo and download the relative unknown utility from AMI to flash our motherboard UEFI chipset. Go ahead: $ doas pkg_add -U nasm unzip dosfstools cabextract p7zip nasm the Netwide Assembler, a portable 80x86 assembler. unzip list, test and extract compressed files in a ZIP archive. dosfstoolsa collections of utilities to manipulate MS-DOSfs. cabextract program to extract files from cabinet. p7zipcollection of utilities to manipulate 7zip archives. $ mkdir sys-freedos-linux && cd sys-freedos-linux $ unzip ../sys-freedos-linux.zip $ cd ~/freedos && mkdir old new $ dd if=/dev/null of=freedos.img bs=1024 seek=20480 $ mkfs.fat freedos.img Create another working directory, cd into it, unzip the archive that we've downloaded, return to the working root and create another twos directories. dd is one of the most important utilities in the unix world to manipulate at byte level input and output: The dd utility copies the standard input to the standard output, applying any specified conversions. Input data is read and written in 512-byte blocks. If input reads are short, input from multiple reads are aggregated to form the output block. When finished, dd displays the number of complete and partial input and output blocks and truncated input records to the standard error output. We're creating here a virtual disk with bs=1024 we're setting both input and output block to 1024bytes; with seek=20480 we require 20480bytes. This is the result: -rw-r--r-- 1 taglio taglio 20971520 Feb 3 00:11 freedos.img. Next we format the virtual disk using the MS-DOS filesystem. Go ahead: $ doas su $ perl stuff/sys-freedos-linux/sys-freedos.pl --disk=freedos.img $ vnconfig vnd0 stuff/fdboot.img $ vnconfig vnd1 freedos.img $ mount -t msdos /dev/vnd0c old/ $ mount -t msdos /dev/vnd1c new/ We use the perl utility from syslinux to write the MBR of our virtual disk freedos.img. Next we create to loop virtual node using the OpenBSD utility vnconfig. Take care here because it is quite different from Linux, but as usual is clear and simple. The virtual nodes are associated to the downloaded fdboot.img and the newly created freedos.img. Next we mount the two virtual nodes cpartitions; in OpenBSD cpartition describes the entire physical disk. Quite different from Linux, take care. $ cp -R old/* new/ $ cd stuff $ mkdir o35jy19usa $ cabextract -d o35jy19usa o35jy19usa_y900.exe $ doas su $ cp o35jy19usa/ ../new/ $ mkdir afudos && cd afudos $ 7z e ../AFUDOS* $ doas su $ cp AFUDOS.exe ../../new/ $ umount ~/freedos/old/ && umount ~/freedos/new/ $ vnconfig -u vnd1 && vnconfig -u vnd0 Copy all files and directories in the new virtual node partition, extract the Lenovo cabinet in a new directory, copy the result in our new image, extract the afudos utility and like the others copy it. Umount the partitions and destroy the loop vnode. Beastie Bits NetBSD - A modern operating system for your retro battlestation (https://www.geeklan.co.uk/files/fosdem2018-retro) FOSDEM OS distribution (https://twitter.com/pvaneynd/status/960181163578019840/photo/1) Update on two pledge-related changes (https://marc.info/?l=openbsd-tech&m=151268831628549) *execpromises (https://marc.info/?l=openbsd-cvs&m=151304116010721&w=2) Slides for (BSD from scratch - from source to OS with ease on NetBSD) (https://www.geeklan.co.uk/files/fosdem2018-bsd/) Goobyte LastPass: You're fired! (https://blog.crashed.org/goodbye-lastpass/) *** Feedback/Questions Scott - ZFS Mirror with SLOG (http://dpaste.com/22Z8C6Z#wrap) Troels - Question about compressed ARC (http://dpaste.com/3X2R1BV#wrap) Jeff - FreeBSD Desktop DNS (http://dpaste.com/2BQ9HFB#wrap) Jonathon - Bhyve and gpu passthrough (http://dpaste.com/0TTT0DB#wrap) ***

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Mark, Tara and Steve talk through the deep and profound challenges of part-time doctoral candidature.  How do we manage the stress while the clock is ticking, particularly when a confirmation of candidature is pending?  We develop some strategies.

The whole gang's complete for episode 4 of The Streamline Podcast by Pop Philtre We discuss Tanim Bala, AlDub's Tamang Panahon and the filing of CoCs and shoutouts to Adele, Biebs and Grantland All music in this episode was created by Lee Rosevere Check him out at the Free Music Archive or at Bandcamp Subscribe to our podcast: http://feeds.soundcloud.com/users/soundcloud:users:160358586/sounds.rss Like us on Facebook: https://www.facebook.com/popphiltre Follow us on Twitter: @PopPhiltre

MASH-UP работа от ANTON COCS   

MASH-UP работа от ANTON COCS   

Episode Download Link0:00 - Intro3:00 - Kickstarter Comics Discussion5:35 - Mandatory Top Cow Reference: The Voice in the Dark by Larmie Taylor6:00 - TheChair and TheChair The Movie10:50 - Lyesmith and Retinax-5 Geek out over a TV show that only lasted 8 episodes. 12:25 - CreepyScarlett - 12:40 - Wynter/Goof - 14:50 Ruin/Wicker15:00 Aero-Girl17:20 - Online Comics Released for Free17:55 Disenchanted - FCBD19:10 Holliday: Mountain Madness22:45 Jack1979The boys of Geekin' discuss the newest (and their fave) COCs (creator owned comics)!Be sure to check out the links below to keep an eye on your favorites!Jack1979http://geekinpodcast.blogspot.com/2014/06/jack-1979-issue-1-review-lyesmith.htmlSupport Jack1979 on Kickstarter!https://www.kickstarter.com/projects/1821725188/jack-1979-issue-1Stalk them on Twitter!https://twitter.com/jonpaulharthttps://twitter.com/tehcrashedmediaKeep tabs on them on Facebook!https://www.facebook.com/Jack1979ComicCreepyScarlett Linkshttp://geekinpodcast.blogspot.com/2014/05/kickstarter-spotlight-creepy-scarlett.htmlSupport the Kickstarter! Keep Creepy Scarlett alive!https://www.kickstarter.com/projects/1473164285/scarlett-and-the-seal-of-solomonBuy the collected first 4 issues of Creepy Scarlett over at DriveThruComicshttp://comics.drivethrustuff.com/product/122796/Creepy-Scarlett-Book-OneStalk/Keep Tabs On/Follow Graeme Buchan on Twitter!https://twitter.com/ScarlettComic And go like Creepy Scarlett on Facebook!https://www.facebook.com/CreepyScarlettNewWorldsComics/Wynter Linkshttp://geekinpodcast.blogspot.com/2014/05/review-newworldscomics-wynter.htmlCheck their website for continues updates.http://newworldscomics.com/Their Twitterhttps://twitter.com/NewWorldsComicsFacebookhttps://www.facebook.com/HopeYouSurviveTheExperienceTumblrhttp://goshdarnit2.tumblr.com/iPad app - Wynter is also available on Comixology!https://itunes.apple.com/us/app/new-worlds-comics/id700320110https://www.comixology.com/Wynter-1/digital-comic/93200Ruin/Wicker/GutterTownhttp://geekinpodcast.blogspot.com/2013/10/comic-book-kickstarter-q-ruinwicker.htmlhttp://darkerandjune.wordpress.com/Instagram!http://instagram.com/darkerjuneTwitter accounts!https://twitter.com/ruincomic https://twitter.com/Darker_Junehttps://twitter.com/guttertowncomichttps://twitter.com/wickercomicFacebook Pages!https://www.facebook.com/wickercomichttps://www.facebook.com/ruincomicTheChairKickstarter!https://www.kickstarter.com/projects/petersimeti/the-chair-a-horror-film-adaptation-of-the-graphicTwitter accounts!https://twitter.com/ALTERNACOMICSCreatorhttps://twitter.com/petersimetihttps://twitter.com/theCHAIRhorrorAero-Girlhttps://www.kickstarter.com/projects/611041940/the-adventures-of-aero-girl-a-girl-and-her-gorilla  4 days left! (As of 6-13-14)Here is the link to #1 https://t.co/kIcRcD1fbGFacebookhttps://www.facebook.com/AdventuresofAeroGirlTwitterhttps://twitter.com/DeWayneFeenstraDisenchantedhttp://www.disenchantedcomic.com/Writer's Twitter!https://twitter.com/sispurrierGoogle+https://plus.google.com/u/0/108057749084143637464Holliday: Mountain Madnesshttp://www.hollidaycomic.com/Like them on Facebookhttps://www.facebook.com/HollidayMountainMadnessGoogle+https://plus.google.com/u/0/101631757982436642184

Concentrating solar technologies compete with other rapidly developing renewable energy sources. To succeed it is vital to lower the levelized cost of energy. There are several parameters that can be optimized to reach this goal, but a key component is the improvement of the resource assessment. A better prediction of the solar resource for new facilities brings down financing costs as financial risks are reduced. Moreover, improved solar resource assessment allows to optimize new facilities in regard to the local insolation conditions. This increases energy and cost efficiency. One parameter that is becoming more and more important for the resource assessment is the circumsolar radiation. It is caused by forward scattering of sun light by cloud or aerosol particles. However, measuring circumsolar radiation is demanding and only very limited data sets are available. As a step to bridge this gap, a method was developed in this study to determine circumsolar radiation from readily available data on clouds and aerosol. Specifically, the effective radius and optical thickness of cirrus clouds were used, as well as area mass loadings of several aerosol components. The core of the method to determine the circumsolar radiation is a fast yet precise parameterization. It allows to compute the circumsolar radiation by simple analytical expressions from previously tabulated coefficients, instead of solving the radiative transfer by time-consuming numerical simulations. The lookup tables were generated by extensive calculations using a specifically adjusted version of the Monte Carlo radiative transfer model MYSTIC. To this end, MYSTIC was enhanced with a realistic radiation source: The point source used so far was replaced by a extended sun disk which features a wavelength dependent brightness distribution. The evaluated aerosol area mass loadings were obtained from the European Centre for Medium-Range Weather Forecasts (ECMWF) as model output of the Integrated Forecast System (IFS). To derive the cirrus cloud properties the APICS retrieval framework was applied to Meteosat Second Generation (MSG) measurements. During the course of this study APICS was optimized regarding the retrieval of optically thin cirrus clouds. To this end, a new ground albedo data set was generated on the basis of MSG measurements which serves as a priori assumption in the retrieval. This new data set is, in contrast the so far used one, consistent to the other assumptions made within the retrieval. This is an important pre-requisite for the successful retrieval of optically thin cirrus clouds. Furthermore, APICS was operated with a new cloud mask based on output of the COCS cirrus cloud property retrieval algorithm. It replaces the formerly used cloud mask from the MeCiDa cirrus detection algorithm. Thereby in the order of 70 to 80 percent more optically thin cirrus clouds can be considered, which allow enough light to pass for operation of a typical solar thermal utility. Considering cirrus clouds the prevailing ice particle shape is an uncertainty factor in the cloud property retrieval as well as in the computation of circumsolar radiation. So far it cannot be determined from MSG but must be assumed a priori. To allow for an uncertainty analysis concerning this parameter APICS was extended to consider several new ice particle shapes in the retrieval process. It was found, the nescience of the ice particle shape leads to an uncertainty of up to 50% in the mean circumsolar irradiance. The newly developed method for the retrieval of circumsolar radiation was validated with ground measurements of the circumsolar ratio (CSR) performed at the Plataforma Solar de Almería (PSA). This showed that the statistical distribution of the circumsolar radiation can be well characterized with both of the two employed ``Baum'' ice particle shape parameterizations. When comparing instantaneous values timing and amplitude errors become evident, tough. For the circumsolar ratio (CSR) the validation yielded a mean absolute deviation (MAD) of 0.11 for both ``Baum'' parameterizations, a bias of 4% and -11%, respectively, and a Spearman rank correlation r_rank of 0.54 and 0.48, respectively. If measurements with sub-scale cumulus clouds within the relevant satellite pixels were manually removed, the agreement of instantaneous values improved. This reflects in the MAD values of 0.08 and 0.07, respectively, and r_rank values to 0.79 and 0.76, respectively. Furthermore, it was found that for aerosol the CSR is strongly underestimated if the IFS output is used head on. Only after adjusting the aerosol mass loadings reasonable values can be obtained. An underrepresentation of large dust particles in the IFS seems most likely to be reason for this. In the future the method developed in this study can be extended and combined with other data sources. While ground-based reference measurements so far only allowed the assessment of the circumsolar radiation at few specific measurement sites, the newly developed method makes it possible to survey arbitrary sites.

Amazing!New Exclusive Deep Mix!Deep in a Paradise!Mixed by DJ Shirshnev 4DJSListen,Dance and drink!Cheers!

Amazing!New Exclusive Deep Mix!Deep in a Paradise!Mixed by DJ Shirshnev 4DJSListen,Dance and drink!Cheers!

Are you ready for Deep to Dance?Let's go!Listen and dance!

Are you ready for Deep to Dance?Let's go!Listen and dance!

RIGHT NOW DEEP MIX FROM 4DJS Only Best Music-IT"S DJ SHIRSHNEV TIME!

RIGHT NOW DEEP MIX FROM 4DJS Only Best Music-IT"S DJ SHIRSHNEV TIME!

Eiswolken und insbesondere hohe Zirruswolken bedecken im globalen jährlichen Mittel bis zu 30 % der Erde und haben deshalb einen signifikanten Einfluß auf das Klima. Eine Besonderheit hoher Eiswolken ist, dass sie einen wärmenden Effekt auf das System Erde und Atmosphäre besitzen können. Dieser wärmende Effekt wird u. a. durch tägliche und saisonale Variationen der optischen Eigenschaften beeinflußt. Um genaue Messungen der optischen Eigenschaften von Aerosolen und Zirruswolken zu erhalten, wurde 2006 die "Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations" (CALIPSO) Mission in einen polaren Orbit gestartet. Mit Hilfe des Hauptinstrumentes, des "Cloud- Aerosol Lidar with Orthogonal Polarization" (CALIOP), können nun optische Eigenschaften von Aerosol- und dünnen Wolkenschichten mit bisher unerreichter Genauigkeit und Sensitivität bestimmt werden. Allerdings erlaubt dieser Orbit mit einer Wiederkehrdauer von mehr als zwei Wochen keine Ableitung von Tagesgängen der optischen Eigenschaften und des Bedeckungsgrades von Zirruswolken, weshalb in dieser Arbeit der Wolkensensor "Spinning Enhanced Visible and Infrared Imager" (SEVIRI) auf dem geostationären "METEOSAT Second Generation" (MSG) Satelliten benutzt wird. SEVIRI deckt mit seinen Messungen fast ein Drittel der Erde ab und reicht von 80 N bis 80 S und von 80 W bis 80 E bei einer räumlichen Auflösung von bis zu 3 km x 3 km im Nadir und einer zeitlichen Auflösung von 15 Minuten. Im Rahmen dieser Arbeit wurde ein gänzlich neuer Ansatz verfolgt, um die Vorteile beider Instrumente (die hohe Sensitivität und Genauigkeit von CALIOP und die hohe zeitliche und räumliche Auflösung von SEVIRI) miteinander zu verbinden: Der "Cirrus Optical properties derived from CALIOP and SEVIRI during day and night" (COCS) Algorithmus basiert auf dem Prinzip künstlicher Neuronaler Netze und leitet die optischen Dicken von Zirruswolken und deren Oberkantenhöhen aus Messungen der Infrarotkanäle des Instrumentes SEVIRI ab, was Beobachtungen sowohl in der Nacht als auch am Tage ermöglicht. Dieses Neuronale Netz wurde mit gleichzeitigen Messungen der optischen Dicken und Höhen der Wolkenoberkante von CALIOP trainiert. In dieser Arbeit wird die Entwicklung von COCS und die Validierung mit zwei unterschiedlichen Lidar-Messungen beschrieben, mit denen von CALIOP und mit denen des flugzeuggetragenen "High Spectral Resolution Lidar" (HSRL). Die Validierungen zeigen die hohe Genauigkeit des hier entwickelten Algorithmus in der Ableitung der optischen Dicken und Höhen der Wolkenoberkante von Zirruswolken. Zusätzlich wurden auch Vergleiche der COCS-Ergebnisse mit zwei weiteren auf SEVIRI basierenden Algorithmen durchgeführt: Zum einen mit dem "METEOSAT Cirrus Detection Algorithm 2" (MECiDA-2), welcher ebenfalls die thermischen Infrarotkanäle benutzt, zum anderen mit dem "Algorithm for the Physical Investigation of Clouds with SEVIRI" (APICS), welcher zur Ableitung der optischen Eigenschaften von Wolken sowohl auf den Infrarotkanälen als auch auf Kanälen im sichtbaren Spektralbereich basiert. Die Validierung zeigt hervorragende Ergebnisse für die Erkennung von Zirruswolken mit einer Fehldetektionsrate von unter 5 % und einer Detektionseffizienz von bis zu 99 % ab einer optischen Dicke von 0.1. Ebenfalls wird eine Standardabweichung von 0.25 für die optische Dicke und 0.75 km für die Höhe der Wolkenoberkante nachgewiesen. Basierend auf fünf Jahren prozessierter COCS-Daten werden die Tagesgänge von Zirruswolken in verschiedenen Regionen der Erde analysiert und diskutiert. Die Ergebnisse zeigen ausgeprägte Tagesgänge des Zirrusbedeckungsgrades und der optischen Dicke, welche sich von den Vorhersagen des "European Centre for Medium-range Weather Forecasts" (ECMWF) unterscheiden. Eine Betrachtung des Bedeckungsgrades hoher Wolken, vorhergesagt durch das ECMWF, und der Ergebnisse des COCS Algorithmus zeigt gut übereinstimmende Tagesgänge in konvektiven Regionen, während Unterschiede in nichtkonvektiven Regionen über dem Nord- (NAR) und Südatlantik (SAR) sichtbar werden. Generell wird vor allem in diesen Regionen ein höherer Bedeckungsgrad mit Unterschieden von 3-10 % durch COCS errechnet. Abschließend werden die Unterschiede der NAR und SAR diskutiert, da im Nordatlantik einer der meist frequentierten ozeanischen Flugkorridore liegt. Hier mischen sich die heißen Flugzeugabgase mit kalten Luftmassen und führen zur Bildung von Kondensstreifen. Diese Kondensstreifen verlieren mit der Zeit ihre lineare Form und können anschließend nicht mehr von natürlich entstandenen Zirruswolken unterschieden werden. Grundsätzlich zeigt sich hier eine starke Korrelation des Tagesganges von Bedeckungsgrad und optischer Dicke der Zirruswolken mit der Luftverkehrsdichte. Es werden Unterschiede von bis zu 3 % im Bedeckungsgrad zwischen NAR und SAR detektiert.

Similarities between the bovine female and women in terms of reproduction and fertility, such as oogenesis, folliculogenesis and reduced fertility with advanced age make the bovine a valuable model for the study of ovarian function and dysfunction as well as reproductive aging in women. The aim of the present work was to investigate the influence of donor age on follicle numbers, yield and quality of COCs obtained by repeated OPU and on the developmental competence in vitro after oocyte maturation in vitro versus in vivo. Further, the ability of oocytes from different age classes to reprogram nuclei of bovine fetal fibroblasts was studied. Since the individual is a major factor influencing parameters of fertility and results of ART in both humans and cattle, the present study used in parts the same animals to rule out inter-individual effects on the response to one or the other approach. Experiment 1 investigated the effect of donor age in non-superstimulated German Simmental heifers (n = 12, 14 months at the beginning of the experiments), young cows in their first lactation (n = 8, 2-4 years) and old cows (n = 8, 10-15 years). A total of 38 OPU sessions were performed in two experimental periods on independent sets of animals from all age classes: 5/5/5 (32 sessions) and 7/3/3 (6 sessions). In spite of a marked influence of the experimental period, a number of parameters were also significantly affected by donor age. The total number of follicles increased with age (P

The objective of this work was to examine follicular and oocyte growth in canine ovaries with light and electron microscopic techniques and to characterize canine oocytes during in vitro maturation. Ovaries of healthy bitches of different ages (4 months to 12.5 years)and breeds were used, which had undergone elective ovariohysterectomy at local veterinary clinics. The ovaries of 15 bitches were fixed in Bouin`s solution or paraformaldehyde (4%) for immunohistochemical studies and of three bitches in Karnovsky`s solution for electron microscopic evaluation. COCs and oocytes were recovered from 61 other bitches by slicing the ovaries. They were then examined before and after in vitro maturation (24 to 72 hours) in modified TCM-199 either by native evaluation or after fixation in paraformaldehyde (4%) and nuclear staining (propidium iodide/Hoechst 33342), immunofluorescence or glycohistochemistry. The evaluation of the fluorescence microscopic staining was performed by confocal laser scanning microscopy. Oocytes and COCs after 0, 24, 72 and 90 hours of in vitro maturation were also subjected to electron microscopic examination. The morphology of the canine ovary in light and electron microscopic aspects is comparable to that of other domestic animals. Primordial, primary, secondary and tertiary follicles were regularly seen. The diameter of the oocytes and of the germinal vesicle, as well as the thickness of the zona pellucida, clearly increases during oocyte development. Growing canine oocytes are characterized ultrastructurally by rapid growth in the number of cellular organelles, particularly mitochondria, smooth endoplasmatic reticulum and lipid droplets. Mitotic division starting at the primary follicle stage can be regularly observed by immunostaining with the proliferation marker Ki-67. Further immunohistochemical studies on ovaries indicate that estrogen receptors alpha and beta, as well as MMP-1, -2, -14 and TIMP-2 show a specific distribution in bitches. Canine oocytes could easily be isolated by slicing the ovaries. The number of recovered oocytes was clearly influenced by the age of the donor bitch but not by the breed, the reproductive status or the transportation time between time of surgery in the veterinary clinic and the recovery of the oocytes in the laboratory. 48% of all isolated oocytes had a dark homogenous ooplasm and multiple dense layers of cumulus cells. After in vitro maturation, morphological changes like the formation of vesicles and the loss of cumulus cells could be observed in most of the COCs. Immediately after recovery, the nuclei of all oocytes were at the germinal vesicle stage, although the chromatin showed different degrees of condensation. While first signs of the resumption of meiosis were seen after 24 hours of culture, only one oocyte in metaphase II could be seen after 72 hours. Nuclear and cytoplasmatic maturation could be detected by electron microscopy for up to 24 hours of in vitro culture, as well as signs of degeneration, which were even more prominent after longer culture periods. The immunoreaction of ZP3beta, alpha-Tubulin and Connexin 43 and the binding sites of the lectins WGA and SBA showed characteristic changes in canine oocytes and COCs before and after in vitro maturation.

Monolayerkulturen von Normal- und Tumorzellen verhalten sich unter Bestrahlung substantiell unterschiedlich. Wir haben ein Ko-Kultursystem (COCs), bestehend aus dreidimensionalen Organkulturen von humanem Bronchialepithels (OCs') und der GFP-transfizierten Lungenkarzinom-Zelllinie EPLC entwickelt, und können in Kombination mit der Durchflusszytometrie den DNA-Gehalt getrennt für Tumor- und Normalzellen analysieren. Damit kann die Wirkung ionisierender Strahlung auf die Proliferation, die Apoptose und die Zellzahl im Verlauf quantifiziert werden. Die humane Bronchialepithel-Zelllinie BEAS-2-B zeigt im Monolayer gesteigerte Proliferation und erhöhte Strahlensenitivität im Vergleich zum normalen Bronchialepithel in der COC. Ebenso ist die Proliferation und Strahlensenitivität der Tumorzellen, wenn als Monolayer kultiviert, erhöht im Vergleich zu Tumorzellen in COCs. Normalepithel-Zellen zeigten mit Tumorzellen in COCs kultiviert, verminderte Proliferation und, nach Bestrahlung keine gesteigerte Apoptose. Diese Daten zeigen, dass mit COCs in Verbindung mit Durchflusszytometrie die Auswirkung ionisierender Strahlung in einem In-vivo-nahen System erfassbar ist und das sowohl die räumliche Organisation als auch die Interaktion von Normal- und Tumorzellen für die Wirksamkeit einer Antitumortherapie entscheidend sind.