Podcast appearances and mentions of felix hoffmann

Felix Hoffmann is an image and cultural scholar and the inaugural Artistic Director of the Center for Photography and Lens-Based Media FOTO ARSENAL WIEN and the Director of FOTO WIEN. From 2005 to 2022, he served as the Chief Curator of the exhibition space C/O Berlin, where he was responsible for exhibitions, programs, and strategy. He curated numerous international exhibitions, including Nan Goldin (2009), Robert Mapplethorpe, Peter Lindbergh (2011), Gordon Parks (2014), Ren Hang and Elfie Semotan (2018), and William Eggleston (2023), as well as thematic exhibitions like Eerily Familiar: Images of Terror (2011), The Last Image: Photography and Death (2018), and Send me an Image: From Postcards to Social Media (2020).  - Follow Felix on Instagram here --> https://www.instagram.com/felix_hoffmann__/   FOTO ARSENAL WIEN is Austria's new center for photography and lens-based media. Since 2023 it has been responsible for the FOTO WIEN festival, and starting in 2025 it will be responsible for the Festival Vienna Digital Cultures with the Kunsthalle Wien. Initiated as a media literacy center by the city of Vienna in fall 2022, FOTO ARSENAL WIEN explores all facets of photography. As a hub for photography and lens-based media in Austria, the institution brings together historical and international topics at the interface between analog and digital worlds as well as between static and moving pictures. FOTO ARSENAL WIEN presents the full spectrum of the medium of photography in up to twelve exhibitions held annually in a one-thousand-square-meter exhibition space—a combination of young talents, still-to-be-discovered photographers, and internationally known artists. - https://www.fotoarsenalwien.at/en/ - https://www.instagram.com/foto_arsenal_wien/   FOTO WIEN is a member of the European Month of Photography (EMOP), a European collaborative project that currently includes photography festivals in Berlin, Brussels, Lisbon, and Luxemburg. Once an insider event for Vienna's lively photography scene, FOTO WIEN has become Austria's largest festival of photographic images in over twenty years of collective commitment. It offers programs for a broad audience that is interested in art and contemporary events as well as a professional audience. FOTO ARSENAL WIEN has been the organizer since 2023. - https://www.fotowien.at/en/ - https://www.instagram.com/foto_wien/   Michael Dooney https://beacons.ai/michaeldooney This episode of Subtext & Discourse Art World Podcast was recorded on 7. March 2025 between Perth (AU) and Vienna (A).

Es passiert ja nicht alle Tage, dass in Wien ein neues Museum eröffnet. Dieser Tage ist es soweit: das FOTO ARSENAL WIEN öffnet seine Pforten. Wir haben Felix Hoffmann eingeladen und mit ihm über Fotografie, Bushalte- und Baustellen gesprochen. Ich wünsche mir sehr, dass das Foto Kompetenzzentrum eine Publikumsmagnet wird. Ich hab' so ein Gefühl, dass da etwas von großer Relevanz passiert. Und ich bin mir absolut sicher, dass mit Felix ein Mensch gefunden wurde, der wie die Faust aufs Auge passt. Wir wünschen dem Foto Arsenal Wien einen guten Start und viele begeisterte Besucher! http://fotoarsenalwien.at Kontakt: redaktion@gieseundschweiger.at; Website: https://www.gieseundschweiger.at/; Redaktion: Fabienne Lubczyk, Lara Bandion; Musik: Matthias Jakisic; Sprecherin: Sarah Scherer; Grafische Gestaltung: Studio Riebenbauer

Leichtathletik: Die Saison neigt sich dem Ende zu. Es ist also Zeit für eine Analyse, allerdings vorwiegend mit der deutschen Brille. Nach der WM 2023 in Budapest, wo es gar keine Medaille für das deutsche Team gab, war dieses Jahr schon erfolgreicher. Benjamin Brömmel war selber ein exzellenter Sprinter und kommt von der Leichtathletik nicht los. So betreibt er den Leichtathletik-Podcast „Mainathlet“ und hat dort immer wieder Leichtathleten zu Gast. Diesmal ist er in der „Sportstunde“ wir ihn begrüßen und analysieren die deutsche Leichtathletikszene. Fussball: Diese Woche startete in Europa die neue Champions-League-Ära mit einem neuen Modus. Das ist natürlich diesmal das Thema für Marcus Höfl in seinem „Sportsflash“. Kegeln: Dann schaut die „Sportstunde“ noch auf eine ganz besondere Bundesliga - die Kegelbundesliga! Ja, gekegelt hat doch irgendwie schon jeder. Ob im Keller einer Kneipe oder in großen Bowling- und Kegelcentern. Aber mit Valentin Olbrecht, Sportkegler in der Bundesliga, schauen wir mal genauer auf diese Sportart. Eishockey: Die Champions Hockey League läuft ja bereits. Und jetzt startet dann auch die DEL. Wie letztes Jahr haben wir Christoph „Ulle“ Ullmann, den ehemaligen Eishockeyprofi u.a. in Köln, Mannheim und Augsburg, gesprochen. Der Experte bei Magenta Sport blickt mit uns auf die neue DEL-Saison. Basketball: Auch die BBL startet in die neue Saison. Am letzen Wochenende gab es das Aufgalopp mit der ersten Pokalrunde, jetzt wird es also in der Liga ernst. Einer ist nicht mehr dabei: Felix Hoffmann. Letztes Jahr war er noch Kapitän in Würzburg bei den Baskets, jetzt hat er die Basketballstiefel an den Nagel gehängt. Er schaut in der „Sportstunde“auf die Favoriten der neuen Spielzeit und berichtet, wie es ihm so ohne Basketball geht. Parkour: Vielleicht hat man ja auch mal Lust einfach über Stock und Stein zu laufen, über Mauern und Hindernisse. Wie wäre es denn mit Freerunning oder jetzt namentlich dann offiziell mit Parkour. Ja, auch das ist eine offizielle Sportart. Dominik Schmoll, seines Zeichens Parkour-Trainer, bringt uns diese Sportart näher. Hier gibt es die Interviews in voller Länge: Apple Podcasts: https://podcasts.apple.com/de/podcast/sportstunde-interviews-in-voller-l%C3%A4nge/id1705390264?uo=4 Spotify: https://open.spotify.com/show/00va1TW4YzTYDCGMpkNMOU Website. https://sportstunde-podcast.de/

Ihr steht vor der Entscheidung, mit einer Pricing-Software zu arbeiten, um die neuesten Möglichkeiten mit KI nutzen zu können und wisst jedoch nicht, welche Software für Euer Business am besten geeignet ist? Dann solltet Ihr in unsere neue „Pricing Friends“-Folge reinhören! Sebastian hat Dr. Markus Husemann-Kopetzky zu Gast, einen führenden Experten auf dem Gebiet der Preisgestaltung. Gemeinsam gehen sie verschiedenen Pricing-Tools auf den Grund und diskutieren, welche Lösung für unterschiedliche Geschäftsmodelle am besten geeignet ist. Markus spricht offen über die häufigsten Fehler bei der Implementierung von Pricing-Tools und erklärt, wie Unternehmen diese vermeiden können, wie KI und Datenanalyse die Preisgestaltung revolutionieren und welche Pricing-Software am besten für Euer Business geeignet ist. Um noch tiefere Einblicke zu bekommen, haben wir die Entwickler und Gründer der jeweiligen Lösungen direkt zum Kurzinterview eingeladen: Martin Wricke, Mitgründer von pricefx, Felix Hoffmann, Mitgründer von 7Learnings, sowie Sebastian Baier, Mitgründer von buynomics sind unsere Special Guests in dieser Folge. Sie teilen ihre Erfahrungen und geben wertvolle Einblicke in ihre spezifischen Lösungen. Martin Wricke zeigt die Vorteile und vielseitigen Einsatzmöglichkeiten von pricefx auf, während Felix Hoffmann erklärt, wie 7Learnings durch datenbasierte Preisstrategien Onlinehändlern zu mehr Umsatz verhilft. Sebastian Baier wiederum präsentiert, wie buynomics datengetriebene Lösungen zur Vorhersage von Kundenverhalten entwickelt. Gemeinsam beleuchten sie die spezifischen Vorteile ihrer Lösungen und wie sie sich voneinander unterscheiden. Link:  Für weitere Pricing-Inisights besucht https://pricingnuggets.com/ ! Über die Gäste:  Dr. Markus Husemann-Kopetzky ist Senior Research Fellow an der Universität Paderborn und ein führender Experte für Preisgestaltung. Er hat über zwölf Jahre Erfahrung in der Beratung und im Management in den Bereichen Finanzdienstleistungen und Einzelhandel. Als Autor zahlreicher wissenschaftlicher Arbeiten und Gründer des Price Management Institute unterstützt er Unternehmen bei der Optimierung ihrer Preisstrategien. Dr. Martin Wricke ist Mitgründer von pricefx und seit 2011 im Bereich der Preisoptimierung tätig. Er verfügt über umfangreiche Erfahrungen in der Pricing-Beratung und hat zuvor in verschiedenen operativen Pricing-Positionen gearbeitet. Martin hat einen Hintergrund in der Preisgestaltung und -beratung und hat sich darauf spezialisiert, komplexe Preisgestaltungsprozesse zu vereinfachen. Sein beruflicher Werdegang umfasst Tätigkeiten in der Preisberatung und im operativen Pricing, wo er seine Expertise in der Entwicklung und Implementierung von Preisstrategien vertieft hat. Felix Hoffmann ist Mitgründer von 7Learnings und hat seine Karriere bei SAP und Zalando begonnen, wo er in der Preisoptimierung tätig war. Er verfügt über umfangreiche Erfahrungen im Bereich Predictive Pricing und hat an der Entwicklung skalierbarer Preisoptimierungslösungen gearbeitet. Felix hat einen akademischen Hintergrund in Wirtschaftsinformatik und seine Fähigkeiten in der Preisgestaltung und im Management von großen E-Commerce-Projekten weiterentwickelt, bevor er 7Learnings gründete. Dr. Sebastian Baier ist Mitgründer und Geschäftsführer von buynomics. Er hat Mathematik und Physik studiert und in diesen Bereichen promoviert. Vor der Gründung von buynomics war er in der Unternehmensberatung tätig, wo er seine analytischen Fähigkeiten und sein Verständnis für komplexe Marktmechanismen weiterentwickelte. Sebastian hat sich darauf spezialisiert, datengetriebene Lösungen zur Vorhersage von Kundenverhalten zu entwickeln und anzuwenden, um Unternehmen bei der Optimierung ihrer Preisstrategien zu unterstützen.

El 10 de agosto de 1897 el químico Felix Hoffmann logró sintetizar el Ácido acetilsalicílico, conocido posteriormente como aspirina.

In this episode, we dive into the story of aspirin and the development of ibuprofen, ending with the experiments that showed the mechanism of how aspirin actually works. Intro 0:12 Review of part 1 0:28 In this episode 1:04 Blocking prostaglandins and willow leaves 2:26 Edward Stone 3:45 Johann Andreas Buchner 4:16 The chemical structure of salicylic acid and creating the synthetic compound 4:44 Dr. TJ MacLagan: The first trial in 1876 and treating acute rheumatism 5:16 Felix Hoffmann: manipulating salicylic acid and aspirin 8:47 How widespread was the use of aspirin for rheumatoid arthritis? 12:04 1938: problems with aspirin and endoscopies 14:58 1950s: long-term use of aspirin and chronic renal impairment 17:12 Dr. Lawrence Craven: the use of aspirin to treat myocardial infarction 18:13 Overview of what we've learned so far 20:48 Stewart Adams: the development of ibuprofen 21:40 A paper lost to time 23:29 How do you test if a drug is anti-inflammatory? 25:25 How do you make better aspirin? 26:55 1960: a trial comparing ibuprofen, baby aspirin and prednisone in patients with rheumatoid arthritis 30:03 Aspirin, ibuprofen and other NSAIDs 32:49 Nobel Prize winner Dr. John Vane 33:40 Dr. Vane: what triggered prostaglandin production? 35:42 Another guinea pig experiment 37:37 Nobel Prize winner Dr. Bengt Samuelsson 39:00 Interesting tidbits: early studies looking at the side effects of NSAIDs 40:01 1968: gastric ulcer formation and prostaglandins in rats 40:25 1973: renal blood flow and prostaglandins in dogs 41:53 1974: aspirin vs ibuprofen vs indomethacin for the heart 44:03 Aspirin vs ibuprofen vs indomethacin 44:20 On the next episode 46:09 Thanks for listening 46:37 We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Adams SS. Inflammopharmacology. 1999;doi:10.1007/s10787-999-0002-3. https://www.aspirin-foundation.com/history/the-aspirin-story/. Buchanan WW, et al. J Rheumatol. 2002;29(6):1321-3. Cryer B, et al. Gastroenterology. 1999;doi:10.1016/s0016-5085(99)70545-7. Desborough MJR, et al. Br J Haematol. 2017;doi:10.1111/bjh.14520. Halford GM, et al. Platelets. 2012;doi:10.3109/09537104.2011.632032. Harris SC, Fosdick LS. Theoretical considerations of the mechanisms of antipyretic analgesia. NWU Bull. 1952;53: 6–9. Jasani MK, et al. Ann Rheum Dis. 1968;doi:10.1136/ard.27.5.457. Robert A, et al. Gastroenterology. 1968;55(4):481-7. Disclosures: Brown reports no relevant financial disclosures.

Sat, 18 May 2024 06:00:00 +0000 https://fazmachtprobe.podigee.io/33-neue-episode cff9875cfaa7ae16d7fdbf51f0af63ab F.A.Z. Machtprobe Mehr über die Angebote unserer Werbepartner finden Sie HIER 33 full F.A.Z. Machtprobe no Kati Schneider und Felix Hoffmann

Zwei Franken, ein Jahrgang. Zwei Karrieren, zwei Wege, zwei Weggefährten, ein Jahr in dem beide ihre Karriere beenden. Dieses Jahr. Basti Doreth und Felix Hoffmann beenden ihre Karriere nach dieser Saison, oder haben sie schon beendet. Wir sprechen mit ihnen über Golf, grandiose Mitspieler und große Spiele. Eine Stunde mit zwei Franken - zum Abschied.

Unser Gast in dieser Folge ist Felix Hoffmann. Er ist Gründer und CEO von 7Learnings, einer Plattform, die es Online-Händlern ermöglicht, ihre Preisgestaltung auf der Grundlage von KI-Daten zu optimieren. Für ihr Produkt benötigen sie hoch qualifizierte Entwickler:innen, die auch ein Verständnis für die Arbeit ihrer Kunden mitbringen. Diese in Zeiten des Fachkräftemangels zu finden, ist nicht einfach, aber 7Learnings gelingt dies sehr gut. Wir erfahren von Felix Hoffmann, wie man Hiring erfolgreich und effizient gestaltet. Im Gespräch mit Martin Möllmann, Senior Investment Manager beim HTGF in Berlin, erzählt Felix Hoffmann außerdem, welche Vorteile es hat, in einem kleineren Unternehmen zu arbeiten. Und welche Rolle regelmäßiges Feedback für die Entwicklung spielt. Ein umfassendes und informatives Gespräch über das Recruiting in einem hochkompetitiven Umfeld, von dem nicht nur junge Unternehmen und Start-ups profitieren können. Ihr wollt mehr über Felix Hoffmann und 7Learnings erfahren? Dann besucht ihn doch auf LinkedIn. Feedback zu unserem Podcast könnt ihr gerne an communications@htgf.de schicken. Wir freuen uns darauf!

Fotobuch-Talk mit Michael Wesely. Freier Künstler, Berlin. Andy Scholz sprach mit Michael Wesely zwischen dem 18. und 22. Oktober 2023 auf der Buchmesse in Frankfurt am Main auf dem Messestand vom Deutschen Fotobuchpreis Halle 3.1 J109. Michael Wesely wurde 1963 in München geboren, studierte von 1986 bis 1988 an der Staatslehranstalt für Photographie in München und von 1988 bis 1994 an der Akademie der Bildenden Künste in München. Er lebt in Berlin. https://wesely.org Publikation: Michael Wesely - The Camera was Present 2010–2020 Steidl Verlag (29. März 2022) ISBN 978-3-95829-865-1 Das Buch bekam die Bronzemedaille in der Kategorie 3 des Deutschen Fotobuchpreises. https://deutscherfotobuchpreis.de/portfolio/the-camera-was-present-2010-2020/ Mit Texten von Marvin Heiferman, Wulf Herzogenrath, Felix Hoffmann, Thomas Weski, Anette Hüsch, Joachim Jäger, Niklas Maak, Jan Maruhn und Sarah Meister Episoden-Cover-Gestaltung: Andy Scholz Episoden-Cover-Foto: Andy Scholz/Martin Rosner In unseren Newsletter eintragen und regelmäßig gut informiert sein über das INTERNATIONALE FESTIVAL FOTOGRAFISCHER BILDER, den »Deutschen Fotobuchpreis« und den Podcast Fotografien Neu Denken. https://festival-fotografischer-bilder.de/newsletter/ Idee, Produktion, Redaktion, Moderation, Schnitt, Ton, Musik: Andy Scholz Der Podcast ist eine Produktion von STUDIO ANDY SCHOLZ 2020-2023. Andy Scholz wurde 1971 in Varel am Jadebusen geboren. Er studierte Philosophie und Medienwissenschaften in Düsseldorf, Kunst und Design an der HBK Braunschweig und Fotografie/Fototheorie in Essen an der Folkwang Universität der Künste. Seit 2005 ist er freier Künstler, Autor sowie künstlerischer Leiter und Kurator vom INTERNATIONALEN FESTIVAL FOTOGRAFISCHER BILDER, das er gemeinsam mit Martin Rosner 2016 in Regensburg gründete. Seit 2012 unterrichtete er an verschiedenen Instituten, u.a. Universität Regensburg, Fachhochschule Würzburg, North Dakota State University in Fargo (USA), Philipps-Universität Marburg, Ruhr Universität Bochum, seit 2022 auch an der Pädagogischen Hochschule Ludwigsburg. Im ersten Lockdown, im Juni 2020, begann er mit dem Podcast. Er lebt und arbeitet in Essen. http://fotografieneudenken.de/ https://www.instagram.com/fotografieneudenken/ https://festival-fotografischer-bilder.de/ https://www.instagram.com/festivalfotografischerbilder/ Https://deutscherfotobuchpreis.de/ http://andyscholz.com/ https://www.instagram.com/scholzandy/

Michael Wesely. Freier Künstler, Berlin. Zitate aus dem Podcast: »Ich habe als Student schon gesagt: Technik soll Engel sein und nicht Teufel.« »Mich interessiert, wie verhält sich der Betrachter zum Bild und welche Bilder will ich als Künstler der Gesellschaft weitergeben.« »Frei nach Watzlawick: Jeder glaubt ja, dass seine Wahrheit ein bisschen wahrer ist, als die der anderen.» »Mich hat immer irgendwie irritiert, das da eine Wahrheit zugedichtet wird, die man ja trotzdem selbst erfinden muss.« »Frei nach Heiferman: Es gibt in unserem Leben nichts, wo die Fotografie sich inzwischen nicht nützlich gemacht hätte.« »Meine Arbeit hat was demütiges. Ich nehme Bilder so hin.« »Ich bin ein Flaneur in der Zeit.« »Digital und analog sind keine Feinde, sondern Brüder.« Michael Wesely wurde 1963 in München geboren, studierte von 1986 bis 1988 an der Staatslehranstalt für Photographie in München und von 1988 bis 1994 an der Akademie der Bildenden Künste in München. Er lebt in Berlin. https://wesely.org https://www.goethe.de/ins/fr/de/sta/bor.html?wt_sc=bordeaux https://www.perlentaucher.de/fotolot/fotografie-als-ein-gewaehrenlassen-gespraech-mit-michael-wesely.html Publiaktion: Michael Wesely - The Camera was Present 2010–2020 Steidl Verlag (29. März 2022) ISBN 978-3-95829-865-1 Mit Texten von Marvin Heiferman, Wulf Herzogenrath, Felix Hoffmann, Thomas Weski, Anette Hüsch, Joachim Jäger, Niklas Maak, Jan Maruhn und Sarah Meister - - - Episoden-Cover-Gestaltung: Andy Scholz Episoden-Cover-Foto: privat Regelmäßig gut informiert über das INTERNATIONALE FESTIVAL FOTOGRAFISCHER BILDER, den »Deutschen Fotobuchpreis« und den Podcast Fotografien Neu Denken durch unseren Newsletter: https://festival-fotografischer-bilder.de/newsletter/ Idee, Produktion, Redaktion, Moderation, Schnitt, Ton, Musik: Andy Scholz Der Podcast ist eine Produktion von STUDIO ANDY SCHOLZ 2020-2023. Andy Scholz wurde 1971 in Varel am Jadebusen geboren. Er studierte Philosophie und Medienwissenschaften in Düsseldorf, Kunst und Design an der HBK Braunschweig und Fotografie/Fototheorie in Essen an der Folkwang Universität der Künste. Seit 2005 arbeitet er als freier Künstler, Autor und ist seit 2016 künstlerischer Leiter und Kurator vom INTERNATIONALEN FESTIVAL FOTOGRAFISCHER BILDER. Seit 2012 unterrichtete er an verschiedenen Instituten, u.a. Universität Regensburg, Fachhochschule Würzburg, North Dakota State University in Fargo (USA), Philipps-Universität Marburg, Ruhr Universität Bochum, seit 2022 auch an der Pädagogischen Hochschule Ludwigsburg. Im ersten Lockdown, im Juni 2020, begann er mit dem Podcast. Im Oktober 2022 integrierte er gemeinsam mit Martin Rosner den Deutschen Fotobuchpreises ins INTERNATIONALE FESTIVAL FOTOGRAFISCHER BILDER in Regensburg. Er lebt und arbeitet in Essen. https://festival-fotografischer-bilder.de/ https://deutscherfotobuchpreis.de https://www.instagram.com/fotografieneudenken/ https://www.instagram.com/festivalfotografischerbilder/ http://andyscholz.com/ https://www.instagram.com/scholzandy/

Felix Hoffmann und Andreas Krobok berichten für eine Woche aus der Ukraine. In der ersten Folge erzählen sie über die lange Anreise und besuchen Butscha.

EinBlick – nachgefragt Podcast mit Interviews und Diskussionsrunden mit Expert:innen des Gesundheitswesens Was macht Purpose Health und welche digitalen Innovationen braucht das Gesundheitswesen? Fachjournalistin und EinBlick-Redakteurin Frederike Gramm sprach mit Dr. Felix Hoffmann, Vorstandsvorsitzender von Purpose Health und Professor für Digital Health. Felix Hoffmann studierte an der Heinrich-Heine-Universität Düsseldorf Medizin, wo er auch promovierte, und hat einen Master in Healthcare Management sowie einen in Medizinrecht. Er leitet die Stabsstelle Medizinische Prozessentwicklung am Klinikum Darmstadt und ist dort auch als Notarzt tätig. Außerdem hat er eine Professur für Digital Health an der Apollon Hochschule der Gesundheitswirtschaft Bremen inne und hat 2021 den Verein Purpose:Health gegründet.

Mein Gast heute: Professor Dr. Felix Hoffmann. Der Facharzt für Orthopädie und Unfallchirurgie ist Leiter der Stabstelle für medizinische Prozessentwicklung am Klinikum Darmstadt, Professor für „Digital Health" an der Apollon Hochschule in Bremen und zudem Ideengeber und Vorsitzender des Netzwerks Purpose:Health e.V. Das Konstrukt Purpose bringt man nicht in erster Linie mit dem Gesundheitswesen in Verbindung und genau deshalb hat Felix Hoffmann den Verein Purpose:Health gegründet. Ziel des Vereins ist es, Beschäftigte im Gesundheitswesen aus verschiedenen Professionen miteinander zu vereinen und darüber zu einer zunehmenden Werteorientierung beizutragen. Denn die Organisationen im Gesundheitswesen stehen vor der Herausforderung, Spitzenmedizin, exzellente Arbeitsbedingungen, Ökonomie und Technologie sinnvoll miteinander zu verknüpfen. Faktisch gehen heute Mitarbeiter im Gesundheitswesen häufig über vertretbare Belastungsgrenzen hinaus und Patienten erhalten nicht immer die beste Gesundheitsvorsorge. Erfahrt im Podcast welche drei Voraussetzungen geschaffen werden müssen, damit der Mensch –Beschäftigte und Patienten – im Mittelpunkt stehen und eine Gesundheitsversorgung auf höchstem Niveau gewährleistet sein kann. Erfahrt von Felix Hoffmann welche Rolle die Digitalisierung hier spielen kann und warum das Neudenken im Gesundheitswesen auch vor einer Veränderung der üblichen Rechtsformgestaltung nicht Halt machen sollte. Erlebt im Podcast einen visionären Vordenker, die sich nicht scheut das Gesundheitssystem in Gänze in Frage zu stellen und auch bei Eigentumsverhältnissen nicht halt macht. Dabei ist er überzeugt, dass das Konstrukt Purpose ein wertvoller Nordstern für einen sinnorientierten und nachhaltigen Wandel des Gesundheitswesens sein kann. Macht euch selbst ein Bild von den Herausforderungen des Gesundheitswesens und welchen Beitrag Purpose hier leisten kann.

Here is the latest from The Year Was, which is that thing I do every week. We are up to episode 181. This time we examine the year 1897 as German Pharmacist Felix Hoffmann synthesizes a stable form of acetylsalicylic acid, the main ingredient in Aspirin, for medicinal application  .  - Theme music by The Tim Kreitz Band https://www.youtube.com/c/TimKreitzAdventures/ https://www.reverbnation.com/timkreitz  -  iTunes: https://podcasts.apple.com/us/podcast/the-year-was/id1458174084  Podbean: https://theyearwas.podbean.com/ Spotify: https://open.spotify.com/show/0Qdd00m2NWvrViVIfAh6kA YouTube: https://www.youtube.com/channel/UCCzWavt8mqXHsC_uRNpU3lQ - Sources: https://en.wikipedia.org/wiki/Felix_Hoffmann https://www.merriam-webster.com/dictionary/alleviate https://www.sciencedirect.com/topics/chemistry/salicin https://www.mountsinai.org/health-library/herb/willow-bark#:~:text=The%20bark%20of%20white%20willow,inflammatory%20effects%20of%20the%20herb http://scihi.org/felix-hoffmann-aspirin/#:~:text=On%20August%2010%2C%201897%2C%20German,under%20the%20trade%20name%20Aspirin https://www.merriam-webster.com/dictionary/rheumatism https://www.sciencedirect.com/topics/chemistry/salicin#:~:text=Salicin%20is%20a%20glycoside%20obtained,the%20barks%20of%20the%20Salicaceae - Photo:  https://en.wikipedia.org/wiki/Felix_Hoffmann#/media/File:Felix_Hoffman.jpg

Die 73-jährige Susan Meiselas hat viele Fotografinnen geprägt, darunter auch Bieke Depoorter. Beiden widmet die Galerie c/o Berlin eigene Ausstellungen. Was sie verbindet: Beide bauen über Jahre Beziehungen zu denen auf, die sie fotografieren.Felix Hoffmann im Gespräch mit Vladimir Balzerwww.deutschlandfunkkultur.de, FazitDirekter Link zur Audiodatei

La aspirina y la heroina son descubrimientos del laboratorio alemán BAYER. Hoy os cuento la curiosidad de Felix Hoffmann.

La aspirina y la heroina son descubrimientos del laboratorio alemán BAYER. Hoy os cuento la curiosidad de Felix Hoffmann.

Zwischen Shootaround und vorvorletztem Heimspiel – unser Würzburg Warrior Felix Hoffmann hat sich die Zeit für unsere finale Folge "Straight Outta Würzburg" in dieser Saison genommen. Wir feiern den Klassenerhalt, blicken auf die aktuelle "Seuchensaison", Felix besondere Rolle als Kapitän und freuen uns über junge Talente mit #PureEmotion bei uns im Club. Vielen Dank an all unsere Fans und Hörer:innen da draußen – schickt uns gerne Feedback, wir verabschieden uns hiermit vorzeitig in die easyCredit BBL Offseason. Bleibt gesund, bis bald und Servus!

Felix Hoffmann, has been the chief curator of the C/O Berlin Foundation since 2005. He studied art history and cultural studies in Vienna and Berlin and worked at the Photo Museum in Munich, the Kupferstich-Kabinett Dresden and the Museum Folkwang in Essen.C/O Berlin is a charitable foundation that presents a cultural program with an international standing. The exhibition venue for photography and visual media shows works by renowned artists, promotes emerging talents and accompanies children, teenagers and adults on their journeys of discovery through our visual culture.Interview with Felix Hoffmann recorded by Michael Dooney on 10. November 2020 at C/O Berlin. NOTESFull Episode Transcript (online soon)Felix Hoffmann (instagram)C/O BerlinOfficial WebsiteC/O Berlin Talent AwardInstagramTwitterFacebookYouTubeAnna Ehrenstein (official website)George Nebieridze (official website)Exhibition: No Photos on the Dance Floor! Berlin 1989 - Today (video)Exhibition: Das Letzte Bild Fotografie und Tod (video)----more----SEBASTIAN DE LA LUZ (audio engineering)InstagramSoundcloudMICHAEL DOONEYHome PageInstagramFacebookTwitterYouTubeJARVIS DOONEY GALLERYHome PageInstagramFacebookTwitter

Eine spezielle Woche: Saisonstart am Samstag gegen Ulm. In der Turnhölle liegt Parkett, Fans werden aber keine kommen. Die Amerikaner haben gewählt, ein Ergebnis gibt es jedoch noch nicht. Wir ordnen die letzten Tage vor dem ersten Heimspiel mitten in der Pandemie mit unserem Kapitän Felix Hoffmann ein.

Willkommen zur zweiten Podcast Folge!Im Interview treffe ich mich mit Dr. Felix Hoffmann, welcher nach seinem Medizinstudium (Fern-)Studiengänge im Health Management und Medizinrecht absolvierte und heute als Gesundheitsökonom die Stabsstelle für medizinische Prozessentwicklung am Klinikum Darmstadt leitet.Welcher Weg hat ihn dort hingeführt? Wie sieht sein Alltag aus? Mit welchem Menschen arbeitet er heute zusammen? Darüber sprechen wir in naturnaher Atmosphäre auf dem Balkon seiner Wohnung in Dortmund.Ich wünsche viel Spaß beim Zuhören.

Tyler Mitchell ist der erste Schwarze Fotograf, der ein Titelbild für die "Vogue" schoss. In seinem ersten Bildband zeigt er nur Schwarze Menschen, die Spaß haben – und schafft so eine eigene Bildsprache, sagt der Kurator Felix Hoffmann. Felix Hoffmann im Gespräch mit Timo Grampes www.deutschlandfunkkultur.de, Kompressor Hören bis: 19.01.2038 04:14 Direkter Link zur Audiodatei

O laboratório alemão Dreser conclui em 6 de março de 1899 um processo de fabricação da aspirina e deposita a patente em Berlim. Este avanço médico é obra do químico Felix Hoffmann, que conseguiu sintetizar o derivado acetila do ácido salicílico em 1893. Dotado de grandes propriedades analgésicas, o produto tem também a faculdade de baixar a febre. A empresa Bayer se apressaria de comercializar o medicamento, dando nascimento a um novo mercado: a indústria farmacêutica. Opera Mundi: análises, vídeos e informações que não são noticiados na mídia convencional: www.operamundi.com.br/apoio★ Support this podcast ★

Our producer Felix Hoffmann takes you on the German Highway - no limits. We investigate why some people have that need for speed and how a serious car accident can change a life. Music by Jam Man and Blue Sessions.

Aspirin ist das bekannteste Arzneimittel der Welt. Es zog einen Nobelpreis nach sich und schaffte vier Einträge ins Guinnessbuch der Rekorde.

Pika in a time of Climate Change The Rocky Mountains are known around the world as a great place to spot wildlife.  Although most visitors to the area are looking for iconic animals like elk, bighorn sheep and bears, some of our tinier residents can be equally exciting. One of the more fascinating alpine animals is the pika.  If you’ve never seen a pika —relax, you’re not alone.  I remember my first sighting.  I was nearing the summit of Nigel Pass in Banff Park, when all of a sudden I started hearing some strange sounds.  They could only be described as a sort of bleating ‘Eeenk’. I would have quickly discounted them as a ground squirrel or marmot had they not come from the middle of a large, seemingly lifeless rock slide.  Somewhere within this maze of boulders was an invisible animal. The problem was only compounded when I moved in for a closer look.  That single ‘Eeenk’ suddenly became several —I was surrounded.  I assured myself that I wasn't going crazy and became determined to discover the maker of these strange noises. As I watched and listened, I was astounded at how the sound of a single call seemed to come from all directions—almost like a ventriloquist throwing his voice.  This must work very well to confuse predators; after all, it confused me.  After about ten minutes, I resigned to the fact that I wasn’t going to find my strange beast. I struggled on with my pack and was about to continue down the trail when a flash of movement caught my eye.  About thirty metres away was a small gray animal.  It resembled a guinea pig and blended in so well with the limestone that I almost lost it in the rocks.  Out came the binoculars for a closer look.   It was hunched on a rock and I could see that it was about 20 cm long with short rounded ears and no visible tail. When I finally returned home to my field guides, I flipped through the pages until, right after the rabbits, I found him.  He was a pika and was part of the order Lagomorpha.  This meant that they weren’t rodents, as I had suspected, but were more closely related to the snowshoe hare (who is also a member of this group). Unlike most other small members of the alpine community, the pika does not hibernate. It spends most of the summer months collecting plants and building large hay piles (some of which may be as large as a bushel) and leaving them to season, much like a farmer leaving out his bales.  It will be these stores that will get it through the eight or nine months of winter. Often, it must leave the security of its rock or talus slope in order to collect these plants.  Recognizing its vulnerability, it spends as little time in the meadow as possible.  Quickly gathering plants, it places them cross-ways in its mouth and returns to the talus. Being related to hares and rabbits makes the pika a hindgut fermenter. Like all herbivores, the digestion of cellulose is done by bacteria in the gut. Unlike animals like elk, moose, and deer, which sport a four-chambered digestive system means that the fermentation process takes place prior to reaching the actual stomach. This also means that they need to essentially cough up their partly digested meals and re-chew them to help further break them down and allow for additional digestion. Unfortunately for animals like snowshoe hares and pikas, the fermentation process takes place beyond the stomach, in the Cecum. They will also have an intestinal tract that can be up to 13 times the length of their body. Once the food passes through the stomach, the fermentation takes place in the cecum and the large intestine before being coated with mucus and being excreted. These are referred to as cecotropes and are eaten again to allow the food to pass through the digestive system a second time to absorb additional nutrients. After this second passing, so to speak, they produce the hard pellets that we would normally associate with animals like rabbits, hares, and pikas. Regardless of which system vegetarians have to deal with, for me, I'm just happy to be a carnivore and not need to chew my cud or my - you know what. Cellulose be damned - give me a juicy steak! Pikas are very carefully tied to the environmental conditions in their homes. They have a fairly high body temperature (around 40 C) and a rise of just a few degrees can be fatal.  This narrow range forces them to live in cooler areas, usually at elevations above 2000 metres. The prospect of warming climates and changing weather patterns are likely to have some very detrimental impacts on animals like the pika. In fact, research done in the Yukon in 2011 by Dr. David Hik of the University of Alberta looked at populations of collared pika in Kluane National Park, in the Yukon. The collared pika is closely related to the American pika that is so common through the Canadian Rockies and has been experiencing some of these climate-related challenges. The fact that pikas don't hibernate means that they rely on several things to make it through the winter, as well as to have reproductive successes. Believe it or not, they need good snowpacks. Snow is a blanket. It never gets cold beneath the snow. If you doubt this, just ask anyone who has spent a night in an igloo or snow cave. For pikas, warm winters with little snowpack mean population declines. The cold is able to penetrate into their subnivean or under the snow world leading to population declines. In the Alberta Rockies, another study done by the Alberta Biodiversity Monitoring Institute in 2014 found that the American pika was the second most vulnerable animal. Pika live on mountaintops. This means that their homes are isolated from populations on adjacent mountaintops. They can't simply migrate into new habitats when the conditions in their home range change in such a way that it's no longer suitable. As an example, if you think about Lake Louise. Pika found around Lake Agnes cannot simply get to Mount Fairview, even though it is just on the other side of Lake Louise. To do so would involve a long migration into low elevation habitats prior to making their way up to the alpine zone of Mount Fairview. Pika live in the alpine because they cannot tolerate the warmer temperatures in the lower, warmer subalpine. Pikas are limited to survive in the habitats they have…as the saying goes: "there's no place like home". Unfortunately for them, it's also the only place that's home.  They may be able to see a new potential home, but they won't be able to get there. Despite this, a report by Chris Shank entitled: Understanding and Respecting the Effects of Climate Change on Alberta’s Biodiversity indicated that they may not be at risk in the near future, at least in Alberta. This belief comes with many conditions, unfortunately, some of them requiring a reduction in greenhouse gases. With the current environmental situation south of our border, as well as Canada's slow pace of change, this seems unlikely to occur. It also assumes that snowpacks continue to be sufficient to support strong pika populations, that meadow plant populations remain consistent, those summer temperatures remain cool enough, and that loose rock, or talus slopes, that the pika call home also remains constant. With warming climates, the forests of the subalpine are beginning to migrate upwards into the alpine. The alpine is a finite habitat. Eventually, you run out of mountain. As long as meadows migrate upwards along with forests, and snow packs migrate uphill as well, and so on, our pikas may be able to stick around. While pikas are on the frying pan locally, they are slipping into the fire in more southerly populations. The further south you go, climate changes are resulting in the two things that make it difficult for pikas to survive - reduced snowpacks and an upward migration of the subalpine. If you travel south to California's Sierra Nevada mountains, pikas have completely disappeared from a 425 km2 portion of their range. Currently, this is the largest area of local extinction or extirpation, so far recorded. In California, the problem has been warmer summer temperatures, resulting in these very heat sensitive pikas overheating. When it's too hot, the pikas seek the shade. When they are in the shade, they're not collecting plants to add to their winter larder. While pika do still exist in areas adjacent to this study, forecasts predict a drop of 97% in pika numbers around Lake Tahoe by 2050. There is one light at the end of this very dark tunnel. For pika, there are very few options in a world of warming climates and reduced snow packs: move, adapt, acclimate, or die! In a recent study in Frontiers of Ecology and the Environment, biologists looked at over 200 studies looking into how amphibians, birds, fish, invertebrates, mammals, and reptiles responded to warming climates. Behavioural responses can occur in much shorter time spans then physiological ones. According to this study, some individual pika populations have managed to adapt to changes by varying their foraging habits, calling new environments home, and finding novel ways to prevent overheating. Pika are found over a huge territory, but individuals don’t tent do move more than a kilometre from the rock pile that they were born. Lack of movement means that individual populations remain isolated from each other, meaning each population may adopt different strategies to dealing with warming temperatures. Some have sought out new micro-environments, taking advantage of deadfall logs, logging debris and forests. If the location is cool enough in the summer, and the snowpack deep enough, they may be able to survive. Some isolated populations in the Columbia River Gorge have managed to obtain as much as 63% of their calories from mosses, which are plentiful both winter and summer. This allows them to be less rigorous in terms of building haypiles during the summer months. Behavioural flexibility may be the catchword for the 21st century. If plants, animals, and birds cannot adapt physiologically to the rapid changes in their ranges then behavioural adaptation is their only option. At least a few populations of pika are taking the challenge and beating the odds. I don't ever want to find myself wandering the loose rock talus slopes of the mountains in summer and not be challenged to find these most perfectly camouflaged critters. Ancient Aspirin I spend a lot of time showing visitors to the mountains signs of animals recorded in the landscape and plant life. Most animals are not designed to be seen. They're designed to blend into the mountain landscape and so, to untrained eyes, they often remain invisible. One thing they can't hide though is the signs that they leave behind. This may be tracks, scats, bits of hair, or even signs of feeding. If you take a look at any trembling aspen tree in the central Rockies and you'll notice that the lower portions of the trunk are heavily scarred. This is due to the fact that the scarring represents mouth level for an elk standing on snow. During the lean winter months, aspen bark is a famine food for elk and they'll peel strips of bark off the lower portions of the trunk. If you look higher up the trunk, you may get a surprise. Sometimes you can find additional marks ascending the trunk, and upon closer inspection, you may find claw marks from a black bear or two that climbed the tree in previous years. Aspen and poplar bark is very easily scarred. Once a bear climbs the tree, the tree will bear the scars for the rest of its life. Once you find a bear-climbed aspen, you'll take special notice as you wander the mountain landscapes looking for additional trees with similar scars. Looking for animal signs helps to make us more aware of the wildlife that is around us but often hidden from view. Our first nations also used the bark of the aspen tree. They would use the inner bark as a medicine, and they would take that for everything from headaches to tummy aches. When we non-natives arrived on the landscape, we scoffed at their heathen witch doctor medicine - heck, they didn't even know what it was good for. They took it for everything. Well today we know that the bark of aspen trees, and its relatives in the willow family, contain a chemical called Salicylic Acid. To us non- natives, we refer to this chemical as aspirin. They were taking it long before we ever rediscovered its medical magic. Modern aspirin can be traced back to Edward Stone, an 18th-century clergyman who wrote that a powdered mixture of willow bark helped 50 patients with malaria-like diseases as well as other illnesses. The modern aspirin we use can be traced back to 1899 when Felix Hoffmann, a chemist at Bayer in Germany used acetylsalicylic acid to help treat his father's rheumatism. I've been telling my guests that first nations have used it for hundreds, perhaps thousands of years before modern medicine caught on. Willow bark was taken by ancient Egyptians to treat aches and pains and even the great Greek physician Hippocrates mentioned its use. Well a new study takes its use way back, and I mean waaaaaaay back - to several Neanderthal skeletons dated from between 42,000 and 50,000 years ago. As it turns out, Neanderthals didn't have great dental hygiene. For archaeologists, this has always been good news. In time, plaque accumulating on teeth will harden into something called calculus, a hard surface made up of minerals and the remains of bacteria along with other microorganisms. Calculus can accumulate, layer upon layer, offering a time capsule of Neanderthal diets. Previous studies of Neanderthal teeth showed that humans and Neanderthals interbred. They also showed that localized populations dined on dramatically different menus. Some were Ward friendly with a high meat diet including animals like reindeer, woolly mammoths, and woolly rhinoceros, while others dined at restaurants that I would never frequent - offering a mostly plant-based menu. Recently a group of scientists analyzed the DNA in the calculus of four European Neanderthals. Two were from Belgium, and two from Spain. They varied in age from 42,000 to 50,000 years old. The tests confirmed that the Belgian Neanderthal was my kind of caveman - dining mostly on woolly rhinoceros, wild sheep, and wild mushrooms. The Spanish Neanderthal were more vegan, eating primarily pine nuts, moss, mushrooms and tree bark. The most interesting result came from one of the skulls from El Sidrón cave in Spain. His teeth showed that he had signs of salicylic acid. Now, this was one sickly Neanderthal. He had dental abscesses and DNA analysis showed that he would have suffered from severe diarrhea from intestinal parasites. If he only had something stronger, like penicillin! This miracle drug was only discovered accidentally in September of 1928 by Dr. Alexander Fleming. After returning from vacation he encountered a messy lab and the mold Penicillium notatum had contaminated some of his Petri dishes. While the rest is history, it's the prehistory that is fascinating in terms of this story. This same 48,000-year-old Neanderthal had traces of Penicillium mold. This means that hominids that predate humans were taking versions of Penicillin at least 48,000 years ago, and likely much longer. This story is a combination of daily guiding meeting podcast curiosity. It's common knowledge in local guiding literature that our First Nations used aspen bark as medicine. However, had I not started this podcast, I wouldn't have been on the constant quest for new scientific studies to share with listeners like you. Aspirin and Penicillin are usually considered "modern" medicines, but this one skull from a cave in Spain has helped us to realize that everything new is old again! Mining our Rivers Way back in episode 15, I talked about the importance of gravel-bed rivers in the Canadian Rockies. You can listen to the episode at mountainnaturepodcast.com/ep015. It's a really cool story and it's worth checking out the show notes or taking a listen prior to continuing this episode if you'd like to get the background material. Recent studies by Dr. Richard Hauer, a professor at the University of Montana, have focused on the unique ecology of gravel-bed rivers in the Rocky Mountains. Hauer recognized that streams in mountain valleys are NOT limited to the narrow channel at the bottom of wide U-shaped glacial valleys. In fact, the actual channel of the river extends from valley bottom to valley bottom, with water percolating across the valley through the gravels. Over millennia, the river has been moving back and forth across its valley, eroding here and depositing sediments there, but never staying the same. If you could take an x-ray of the valley bottom, you would see a mosaic of sediments including cobbles, gravels, and finer sediments. Above ground, the valley shows various levels of succession with flowing channels, ponds, old and new channels, dry gravel beds and vegetation varying from mountain avens flowers to old-growth spruce. Water though, does not see these boundaries, and flows from one side of the valley to the other, quietly flowing between the cobbles and other sediments, allowing for an entire ecosystem of aquatic life to persist far away from today's river channel. The mountain ecology around us has been built by 10,000 or more years of rivers changing, migrating, eroding and depositing. It's this change that is the dynamic lifeblood of the river valley ecosystem Now what might happen if you decide to mine that gravel-bed river? If we accept that a gravel-bed river IS really an entire valley and not just a river, then the consequences of disrupting any part of that ecosystem can be significant. In a story in Alberta Views Magazine, former Banff Park Superintendent Kevin Van Tighem talks about a well drilled a kilometre away from the Flathead River in Montana. It wasn't surprising that it produced beautifully clean water, but what was surprising was that it also produced stoneflies. These aquatic insects are found in fast-flowing mountain streams, but they were not expected this far from the river. Well as Dr. Hauer has shown, rivers are not a channel, but a valley-wide ecosystem. The stoneflies lived in the gravels, a long way from the active channel. So let's take a more detailed look at the Bow River Valley as an example. The Bow River occupies just a narrow ribbon in the centre of the valley. On either side, the valley stretches from Silvertip to Quarry Lake. Is the river just the river? Not at all. The river is the valley. Anything we do to the gravels of the valley will affect the river itself. In fact, there's far more water in the gravel then there is in the river channel. Just because it looks like land, it doesn't mean that it IS land. Unfortunately, in Alberta, gravel is a commodity. As far as industry is concerned, gravel is known as "aggregate" and it is a hugely valuable commodity. Gravel mining companies employ lobbyists who extol the benefits of cheap gravel to ill-informed politicians, who look at campaign donations, and, well you get the story. According to Van Tieghen's article, prior to 2011, Alberta regulators rarely approved gravel mines on floodplains, however the provincial Conservatives approved the Alberta Surface Water Body Aggregate Policy in January of 2011. This new policy signaled open season on gravel pit mining in the province. The floods of 2013 really helped to bring the folly of gravel pit mining to the forefront. Water flows, it's unrelenting and continuous. Add additional flow to the channel, and water will also percolate throughout the entire gravel river ecosystem. Three common problems that gravel-river mines cause include depletion of aquifers, losses to the fishery, and in particular, "pit capture". If you dig a gravel pit near to a gravel river channel, the river will tend to be drawn towards the gravel pit with the potential of essentially 'capturing' the pit. This can end up cutting a new channel causing unexpected erosion, destruction of property, and the loss of fish stocks. Essentially, if you build it, it may come! You can see how inchannel gravel mining ant pit capture works. At one mine on the North Saskatchewan River, operated by Mixcor, a company whose website boasts of "a history of caring", their Dahm gravel pit on the North Saskatchewan River was inundated during the 2013 floods. This flood was fast and relentless, just as it was through the Bow River Valley. As the groundwater inundated the mine, followed by the surface water until the entire river course was drawn towards the mine. Very quickly, mine machinery was buried and toxins from the mine began to leach into the 'new' river channel. Along with the toxins, the excessive sediment drowned spawning beds and damage the gills of adult fish. Fish stocks declined by up to 50% from this one case of pit capture. Keith Rae, the owner of Get Hooked Fishing Adventures carefully documents his companies catch rates. Before the flood, he recorded 2,851 catches, but after the flood, he only recorded 1,197. In 2014, it was even worse with only 1,305. Upstream from the pit capture, the numbers remained consistent. As Van Tighen relates in his story, glaciers were great purveyors of gravel, distributing vast amounts in areas far from gravel-bed rivers. The problem is that it is more expensive to mine. As Kevin states: "Glaciers left lots of upland gravel in Alberta. There is no need to steal it from our rivers. The only reason mining river floodplains is profitable is because gravel operators don’t pay for the dead fish, depleted water wells, diverted river channels and downstream siltation. We do." So far the provinces NDP government has not moved to change the regulations. Alberta is glacier country. It's full of gravel. Let's just start to take it from areas outside of these underground channels. That's what we used to do prior to 2011. Water is the issue of the 21st century. Scientists like Dr. Hauer are helping us to better understand the delicate ecosystems that we call home. Naturalists like Kevin Van Tighem have also been helping visitors to the Canadian Rockies understand and experience the mountains for some 30 years. His newest book entitled Our Place: Changing the Nature of Alberta is now available from Rocky Mountain Books. You can also order it from Amazon.ca at the following link: http://amzn.to/2xQlA3Y. And with that, it's time to wrap this episode up. Don't forget that Ward Cameron Enterprises is YOUR source for step-on, hiking, and snowshoe guides as well as workshop facilitators and keynote speakers focusing on all things related to the mountain west. If you'd like to reach out personally, you can contact me through the contact link on this page or hit me up on Twitter @wardcameron. You can also visit our Facebook page at Facebook.com/wardcameronenterprises. If you'd like to check out the shown notes at www.mountainnature.com/ep048, you can find additional links as well as videos that help illustrate the concept of mining gravel-bed rivers. And with that said, I'm off to Churchill to guide polar bear viewing trips for the next few weeks. I'll be really busy with the bears between the 23rd of October and November 10th so please bear with me if you don't see an episode for a few weeks. This podcast is here to stay so I'll post as my time permits but be back full-time upon my return in November. And with that said, it's an awesome day today so I'm off to go hiking.

On this date in 1899, Bayer registered the name “Aspirin” as a trademark. Here are some things you might not have known about aspirin. Aspirin is also known as acetylsalicylic acid. People have been using willow and myrtle trees, both rich in salicylate for thousands of years to treat pain and fever. Aspirin is a non-steroidal anti-inflammatory drug, in the same class as ibuprofen and naproxen. It’s a pain reliever, fever reducer and it fights inflammation. It works by suppressing the production of prostaglandins and thromboxanes. Prostaglandins are involved in the transmission of pain information, modulation of the thermostat in the brain and inflammation. Thromboxanes are responsible for the gathering of platelets that cause blood clots, which can lead to heart attacks. It proved difficult and wasteful to extract salicylic acid from plants, but in 1860 Hermann Kolbe figured out how to synthisize it. The synthesized drug had many of the positive effects of aspirin, but had negatives including weakening of the heart, gastric irritation and an intense bitter taste. In 1897, Bayer chemist Felix Hoffmann began working on how to make salicylic acid less irritating. It’s thought he began his research because his father had suffered from the side effects of sodium salicylate used to treat rheumatism. Using existing research, he discovered a better method for creating acetylsalicylic acid. Bayer would credit Hoffman as the inventor of aspirin, when in reality he refined the process of making it. Testing of what would become known as aspirin was delayed by company bureaucracy. It would have to wait even longer because Bayer’s testing department was busy testing diacetylmorphine, which would be become better known as heroin. The name heroin is a reference to the quote “heroic” feelings it gave the testers. Eventually aspirin was tested and was found to have few of the side effects of its predecessors. When it came time to name the drug, there were two final options: aspirin and euspirin. Aspirin was derived from its chemical name in German: Acetylspirsäure. Euspirin had a similar origin, but included the prefix eu- meaning good, as in euphemism. Aspirin was originally sold in powder form. However, this made it difficult to prevent competitors from making confusingly similar products. So Bayer began pressing aspirin into standardized tablets. During World War I, Bayer had its American assets seized, including its name and logo. It was purchased by Sterling Products, Inc. After World War II, aspirin lost market share to new drugs like acetaminophen and ibuprofen. In the 1980s when both new drugs were available over the counter, aspirin had a small portion of the pain reliever market. It was hurt even further by the link of aspirin consumption by children to Reye’s Syndrome, a potentially fatal disease. Soon after, aspirin’s effectiveness at reducing heart attacks was brought to light and the drug regained its place as the top-selling pain reliever in the U.S. In 1994, Bayer purchased Sterling Products and regained use of its name, logo and products in the United States. Our question: What year was heroin made illegal in the United States? Today is Independence Day in Ghana. It’s unofficially Dentist’s Day, National Oreo Cookie Day, and National Frozen Food Day. It’s the birthday of illustrator Will Eisner, who was born in 1917; author Gabriel Garcia Marquez, who was born in 1927; and basketball player Shaquille O’Neal, who turns 45. Because our topic happened before 1960, we’ll spin the wheel to pick a year at random. This week in 1979, the top song in the U.S. was “I Will Survive” by Gloria Gaynor. The No. 1 movie was “The Deer Hunter,” while the novel “Chesapeake” by our man James Michener topped the New York Times Bestsellers list.  Weekly question: For which book, later turned into a movie, did James Michener win the 1948 Pulitzer Prize for fiction? Submit your answer at triviapeople.com/test and we’ll add the name of the person with the first correct answer to our winner’s wall … at triviapeople.com. We'll have the correct answer on Friday’s episode. Links Follow us on Twitter, Facebook or our website. Also, if you’re enjoying the show, please consider supporting it through Patreon.com Please rate the show on iTunes by clicking here. Subscribe on iOS: http://apple.co/1H2paH9  Subscribe on Android: http://bit.ly/2bQnk3m  Sources https://en.wikipedia.org/wiki/Aspirin https://en.wikipedia.org/wiki/History_of_aspirin https://en.wikipedia.org/wiki/Bayer https://en.wikipedia.org/wiki/Pulmonary_aspiration https://en.wikipedia.org/wiki/Paracetamol https://en.wikipedia.org/wiki/Nonsteroidal_anti-inflammatory_drug https://en.wikipedia.org/wiki/COX-2_inhibitor https://en.wikipedia.org/wiki/Antipyretic http://www.narconon.org/drug-information/heroin-timeline.html https://en.wikipedia.org/wiki/Anti-Heroin_Act_of_1924 https://en.wikipedia.org/wiki/March_6 https://www.checkiday.com/3/6/2017 http://www.biography.com/people/groups/born-on-march-06 http://www.bobborst.com/popculture/numberonesongs/?chart=us&m=3&d=6&y=1979&o= https://en.wikipedia.org/wiki/List_of_1979_box_office_number-one_films_in_the_United_States

Als Naturheilmittel war die Salicylsäure schon lange bekannt. Nur leider war sie schlecht verträglich. Dann hatte Felix Hoffmann die entscheidende Idee. Autorin: Christiane Neukirch

 In 2003, a leather basket filled with cannabis leaf fragments and seeds was found next to a 2,500- to 2,800-year-old mummified shaman in the northwesternXinjiang Uygur Autonomous Region of China.[136][137] Cannabis is also known to have been used by the ancient Hindus of India and Nepal thousands of years ago.    Contemporary uses of cannabis are as a recreational or medicinal drug, and as part of religious or spiritual rites; the earliest recorded uses date from the 3rd millennium BC.[10] In 2004, the United Nations estimated that global consumption of cannabis indicated that approximately 4% of the adult world population (162 million people) used cannabis annually, and that approximately 0.6% (22.5 million) of people used cannabis daily.[11] In the United States, cannabis is the most commonly used illicit drug (under federal law); 5.1% of Americans said they used marijuana in the past 30 days. In 1977, 38% of 12th graders reported using cannabis in the past month; in 2011, 23% of the same age group reported using cannabis in the same time span.           Opium   In June 1840 the British fleet of 16 warships and 27 transports carrying 4,000 men arrived in the Pearl River Delta, near Humen. Among them was the Nemesis, a new iron warship armed with a deadly weapon - the Congreve rocket launcher, able to fire exploding rockets up to a distance of two miles. The Chinese were prepared, but their antiquated defences were no match for the British. Their static canons and armada of war junks were destroyed in just five and a half hours. Over the next two years the British navy travelled up the coast towards Shanghai. Chinese troops, many of whom were addicted to opium, were overwhelmed at every stage. The British bombardments resulted in a considerable loss of life - between 20,000 and 25,000 Chinese were killed. Britain lost just 69 men.           Heroin Diacetylmorphine was first synthesized in 1874 by C. R. Alder Wright, an English chemist working at St. Mary's Hospital Medical School in London. He had been experimenting with combining morphine with various acids. He boiled anhydrous morphine alkaloid with acetic anhydride for several hours and produced a more potent, acetylated form of morphine, now called diacetylmorphine or morphine diacetate. The compound was sent to F. M. Pierce of Owens College in Manchester for analysis. Pierce told Wright: Wright's invention did not lead to any further developments, and diacetylmorphine became popular only after it was independently re-synthesized 23 years later by another chemist,Felix Hoffmann. Hoffmann, working at the Aktiengesellschaft Farbenfabriken (today theBayer pharmaceutical company) in Elberfeld, German   Later, as with Aspirin, Bayer lost some of its trademark rights to heroin under the 1919 Treaty of Versailles following the German defeat in World War I.[65]       The BBC reported that "Worldwide, the UN estimates that as of 2005, there are more than 50 million regular users of heroin, cocaine and synthetic drugs."[13] Global users of diacetylmorphine are estimated at between 15 and 21 million people aged 15–64.[1       LSD   Modern medicine knows about ergot, but has rarely seen it in the form of an epidemic disease.* It is a black fungus that grows on wet grain, contains chemicals that powerfully affect the blood vessels and the nervous system. Drugs that were legal pics tomorrowIn the Middle Ages, growing uncontrolled in wet summers, ergot was no such helpful friend. The disease was called "St. Anthony's Fire," and raged periodically through Europe. Monastic chroniclers wrote of agonizing burning sensations, of feet and hands blackened like charcoal, of vomiting, convulsions and death. Whole villages were driven mad.     The British Army thouht a brief moment that LSD might aid there forces A crew of British military men were each given LSD-25 (Acid) while on the field. Here is what happened:   2 min video http://www.youtube.com/watch?v=n-rWnQphPdQ   There's a part of the video missing, they mentioned that one of the men nearly succeeded in befelling a tree, using only a spade

Als Naturheilmittel gegen Schmerzen und Fieber war die Salicylsäure schon lange bekannt. Nur leider war sie schlecht verträglich. Am 10. August 1897 hatte Felix Hoffmann dann die entscheidende Idee - und erfand das Aspirin. Autorin: Christian Neukirch