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We're back from our short summer break with some classic comedies! Join us as we discuss the costumes in Monty Python and the Holy Grail and Spaceballs. A fun time is had by all, including the guys redoing Jojo's gutters who really wanted to make sure their hammering was heard (sorry about that).Follow along with the visual analysis via these links!Monty Python: Instagram, Pinterest Spaceballs: Instagram, Pinterest Questions? Comments? Suggestions for future episodes? Email thecostumeplot@gmail.com. Follow us: Jojo Siu on IG @jojosiucostumes Sarah Timm on IG @breathcue The Costume Plot on Youtube, Instagram
We're counting down the Top 10 Parody Movies of All Time — from the classics that redefined comedy to the underrated gems that still have us laughing today. Whether you're a fan of slapstick, sharp satire, or clever genre spoofs, this list has something for every movie lover.Join Brody, Charlie, and 2-Dong Dylan from Talk Talk Punch as we rank the funniest parody films ever made, share behind-the-scenes trivia, and debate which spoofs nailed their genre the best. Expect laughs, surprises, and maybe a little controversy over what really counts as a parody.If you love comedy movies, cult classics, and long-form movie podcast discussions, you won't want to miss this one. We cover legendary titles like Airplane, The Naked Gun, This Is Spinal Tap, Spaceballs, Young Frankenstein, Monty Python and the Holy Grail, and more.What's your favorite parody film? Drop it in the comments and let's keep the conversation going!
We're counting down the Top 10 Parody Movies of All Time — from the classics that redefined comedy to the underrated gems that still have us laughing today. Whether you're a fan of slapstick, sharp satire, or clever genre spoofs, this list has something for every movie lover.Join Brody, Charlie, and 2-Dong Dylan from Talk Talk Punch as we rank the funniest parody films ever made, share behind-the-scenes trivia, and debate which spoofs nailed their genre the best. Expect laughs, surprises, and maybe a little controversy over what really counts as a parody.If you love comedy movies, cult classics, and long-form movie podcast discussions, you won't want to miss this one. We cover legendary titles like Airplane, The Naked Gun, This Is Spinal Tap, Spaceballs, Young Frankenstein, Monty Python and the Holy Grail, and more.What's your favorite parody film? Drop it in the comments and let's keep the conversation going!
This week we discuss the film EXCALIBUR! The magical sword of Excalibur starts off in the hands of British lord Uther Pendragon (Gabriel Byrne) and then, years later, finds its way to his bastard son, Arthur (Nigel Terry), the knave destined to become king. Aided by the sorcerer Merlin (Nicol Williamson), Arthur fulfills his fate by bringing together the Knights of the Round Table at Camelot and unifying the country. However, this flawed monarch faces greater tests ahead in pursuit of love, the Holy Grail and his nation's survival. Hear our take on the film and on the review of SISKEL and EBERT.SUBSCRIBE TODAY!Visit thecultworthy.comVisit https://www.themoviewire.comVideo: https://www.youtube.com/@back2thebalcony
Are you over-stuffing your online course with content, thinking it's more valuable? This is the #1 mistake that leads to student overwhelm and lower sales! This episode reveals a simple framework for creating a "Goldilocks Course" that's perfectly potent and focused, so you can stop fearing 'not enough' and start delivering exactly what your students need to get results.Learn how to:Identify the expert's fatal flaw: Over-stuffing a course and how it leads to student overwhelm and burnout.Define your course's "Holy Grail" outcome: The single guiding star that dictates every piece of content you include.Apply the "Direct Impact" Filter: A simple, three-step framework for cutting out "nice-to-have" content and focusing only on what gets students results.Weekly Action Item:Define Your Holy Grail Outcome: Get crystal clear on the one specific, tangible result your students will achieve by the end of your course. Write it down and keep it visible.Apply the "Direct Impact" Filter: Take one module or lesson from your course (or outline) and, for each piece of content, ask: "Does this directly help my student achieve the Holy Grail outcome?"Create a "Parking Lot": Start a separate document or list for all the "nice-to-have" ideas you decide to remove from your core course.Show Resources: Check out all podcast episodes and full transcripts (www.digitalcoursecreatorguide.com/podcast)Follow me on Facebook (facebook.com/digitalcoursecreatorguide) and on Instagram (instagram.com/digitalcoursecreatorguide) for daily tips and ideasWork With Dr. Moira:Make sure that your content is accessible with The Accessibility Mini Course for Online Creators. (https://digitalcourse.pro/accessibility)
In the forty-seventh episode of Season 11: The Son of Cult Flicks, Kyle is joined by screenwriter August Gummere and editor Kristi Shimek to break down the deconstructionist comedy about Arthurian legend, extreme class division, and the false notion of god granted nobility in the exquisitely crafted and thoroughly surrealist masterpiece from the Beatles of comedy in Monty Python and the Holy Grail (1975).
This is the holy grail of altcoin setups. Finding a project that just launched yesterday, has a tiny market cap, real technology, and has no VCs or pre-sale hype? This is very rare and does not come along very often. The tailwinds behind Ethereum altcoin season could propel this utility project to extreme heights, and we are all early to it.
Personally, if someone showed me what I'm about to show you, I would not believe them. I would immediately say, “No way! What's the catch???”. As much as it would disappoint me for you not to consider what I talk about in this week's episode of the podcast, I'd truly understand. If you are looking for a way to create some crazy return on investments (“ROI's”) in your monetary world, then you need to do what I'm doing! None of this is a Holy Grail or “get rich quick”. None of this is easy. But the math is the math and when you see how all the numbers fit together, I think the strategy is something worth seriously considering. If you are a day trader who wants to keep your risk to a minimum while truly opening up the world of upside potential, then this is a discussion you won't want to miss! Let's get to it!
Bill reads a book report called “Bloodline of the Holy Grail” by Laurence Gardner. Originally broadcast May 18, 1998.Copyright Disclaimer: - Under section 107 of the Copyright Act 1976, allowance is made for FAIR USE for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statutes that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of FAIR USE.
Welcome to the BCJ Podcast, presented by BearcatJournal.com! Join Chad Brendel and David Simone this week as they give a camp update before diving in to what it takes to bring a European student over the pond to play basketball. Be sure to stop by the Holy Grail for a Cincy Light, with 50 cents per order supporting UC athletics! #Bearcats #Big12 Like and subscribe for more Bearcats updates and visit bearcatjournal.com! Time Stamps are brought to you by Turtle's Brew! Enjoy zero-sugar, zero-carb, gluten-free bourbon-infused sweet tea with 6% ABV in flavors like cherry lime, raspberry peach, orange vanilla, lemonade tea, and strawberry mint. Available at over 50 locations in Greater Cincinnati and 100+ across Ohio. Find your nearest spot at turtlesbrew.com! Time Stamps: 0:00 - 1:11:00 Camp Update 1:11:00 - 1:23:12 Adding Another International Player
Constellations, a New Space and Satellite Innovation Podcast
The promise of seamlessly roaming across satellite networks in different bands and different orbits is that much closer to reality. A new breakthrough in multi-band antenna technology holds the potential to make communications as seamless and automated as the cellular networks used today. Listen to Ryan Stevenson, Chief Scientist at Kymeta talks about the capabilities of the new multi-band antenna technology and discuss the potential it offers to re-define satcom connectivity for a range of applications from military to aero.
THE LEAGUE OF IRELAND POD | "The Holy Grail for Irish clubs!" | Can Drogheda push for Europe? | Off The Ball On this week's League of Ireland Pod, Stevo is joined by Gareth McGlynn and Vinny Perth to look ahead to a busy week for Irish clubs, including some exciting European fixtures, and some more relegation scraps. Can Drogheda push on for European Football? Will Galway United be safe? The League of Ireland on off The Ball with Rockshore 0.0
In this third episode of the Holy Grail of Investing Podcast, Tony Robbins and Christopher Zook sit down with Jason Ballard, founder and CEO of ICON. ICON is one of the most disruptive technology companies of the past decade as they redefine our understanding or home construction using 3D printing, robotics, software and advanced materials. Jason's vision stretches from solving the world's housing crises to partnering with NASA to build structures on the Moon! Jason's personal story is one of fearless faith, personal trials and perfecting the art of “joyful grit.”
In Episode 19, Hands of Z hits its defining moment. After months of searching, speculating, and digging through dusty archives, Shawn and Keith strike gold — twice. Thanks to the WWE Vault Network, the long-lost Omni bout between Ronnie Garvin and Larry Zbyszko for the National Television Title has finally surfaced. But that's not all. Shawn uncovers an additional match from his personal collection — giving us two high-stakes Garvin vs. Zbyszko encounters, back-to-back. Match #1: Ronnie Garvin (c) vs. Larry Zbyszko 1983 – National TV Title Match Garvin defends the National Television Championship in a rarely seen gem that captures both men at their gritty best. Match #2: Ronnie Garvin vs. Larry Zbyszko 1984 – Tournament Bout An open-round tournament match with a shot at Ric Flair on the line. High intensity, raised stakes, and two veterans fighting for a date with destiny in Baltimore! This is the moment the series has been building toward. Two matches, real stakes, pure storytelling — and the clearest look yet at the physical, psychological chess match between Garvin and Zbyszko. This isn't just another episode — it's the Hands of Z holy grail.
Part 3 of my conversation with guest Phil Stacey about concerts we'd like to go back in time to see. Show notes: Jay: Bowie on the Ziggy Stardust tour in 1973 Never saw Bowie Phil: Grateful Dead's famous Cornell show 5/8/77 The Holy Grail for Deadheads Jay: Canadian art rock weirdos Max Webster in southern Ontario 8/9/79 Band split up in 1981 as singer-guitarist Kim Mitchell went solo Opened for Rush in the U.S. in the mid- to late '70s Phil: The Stones at the Boston Garden, 1972 Jagger and Richards were arrested in Providence and Boston mayor bailed them out in time for the Garden show Mick Taylor era was notable Jay: Van Halen at Oakland Arena in June 1981 A few songs were captured on video; VH fans have hoped for more Phil: Zeppelin at Berkeley, Calif., September 1971 Touring before their fourth album was released Playing some of their acoustic songs Jay: SST legends Husker Du at the Channel in Boston 9/30/84 In the middle of a killer stretch of albums; this one was for Zen Arcade Two classic albums were released the next year Phil: Allman Brothers at the Fillmore East in 1971 Original lineup including Duane Allman Jay and Phil: The Who live at University of Leeds on Valentine's Day 1970 Played a show at Hull the following night We're going to see the Who at Fenway later this month Band was at the literal peak of their powers First release of Live at Leeds was only six songs Longer versions have come out; full set was 33 songs No video of this show unfortunately Completely Conspicuous is available through Apple Podcasts. Subscribe and write a review! The opening and closing theme of Completely Conspicuous is "Theme to Big F'in Pants" by Jay Breitling. Voiceover work is courtesy of James Gralian.
Writing is hard, but as with any hard thing worth doing, that hardness comes in degrees. What is the hardest part of the creative process? 12 authors reveal their picks.Featuring, from 47North:Shannon Fay, author of Innate MagicFrom Engen Books Ltd.:Chelsea Bee, author of London CallingSarah Thompson, author of The Love of SummerJennifer Shelby, author of Plague of the DreamlessFrom Marvel and IDW comics:Heather Antos, editor on Star Wars and GwenpoolFrom Anstruther Press:Daze Jefferies, author of Water/WeptFrom Breakwater Books Ltd.:Olivia Robinson, author of The Blue Moth MotelGemma Hickey, author of Almost FeralClaire Wilkshire, author of The Love OlympicsAnd from self-publishers and writing-related fields: Alisha Morrissey, Heather Reilly, author of Knight's Surrender, and Dianna Brown!Originally broadcast on August 18, 2025 on CHMR 93.5 FM in St. John's, and on other great stations across the country. Check out As Loved Our Fathers, the latest book from Write Project host Matthew LeDrew: https://amzn.to/3HB7BABIt's a hunt for the Holy Grail taken on by an American Anthropologist and a Newfoundland History professor that unveils hidden secrets within Newfoundland history! Support the showProduced and recorded at CHMR 93.5 FM in St. John's, Newfoundland. Listen on CHMR online at http://www.chmr.ca/This program is sponsored by:Engen Books: Checkout Engen titles at http://www.engenbooks.com/Or sign up for their newsletters at: The Write Project signup for FREE book: http://eepurl.com/c8W9OTEngen Horror Society Signup for FREE book: http://eepurl.com/c8YemrFantasy Files signup for FREE book: http://eepurl.com/c8X4zLEngen's Science-Fiction Newsletter for FREE book: http://eepurl.com/ir5JmgThis recording copyright © 2024 Matthew LeDrew
Ped, Burk and Timmy welcome on Burk's classmate, Grace, to open the show, to discuss their recent 20-year reunion, or lack thereof. Grace also answers the hard hitting 90s girl questions before she leaves us. The boys then discuss drive thru etiquette, Adam wanting to grow his beard out just so he can have the full barbershop experience, Adam has found the holy grail of pizza, and Burk's perfect song. For the Meat, Mm!, the guys give their Mt Rushmore of "All-Time Wrestling Moments" in honor of Hulk Hogan. Take a walk with us to the 90s boys bedroom to close the show. Love y'all. Hut Hut.
The epitome of 21st century takes on 20th century _ from space movies, this James Gunn classic references Henelotter, Tremors, The Thing, Big Trouble in Little China, The Toxic Avenger, Goosebumps, Alien, Predator, Society, Shivers, and possibly even Monty Python and the Holy Grail. The make-up and practical effects pair perfectly with 2006's digital effects and the over-the-ham acting of Nathan Fillion, Elizabeth Banks, Michael Rooker, and Gregg Henry. This one will fill you up to bursting but still leave you hungry for more!
This week EPA administrator Lee Zeldin began the process of negating the 2009 “Endangerment Finding” that was, as President Obama called it, the ‘Holy Grail of Climate Change Regulation.' This was where the idea that the very byproduct of Human existence, Carbon Dioxide, could be regulated as a pollutant. So, here in Viginia we have the Virginia Clean Economy Act that was passed in 2020 by the Democrat-majority General Assembly and signed into law by Governor Ralph Northam. If you have heard about “California-ing Virginia,” this is the act that did that. Connecting Virginia's environmental regulations to California's including getting to “net zero” carbon emissions by 2030. This law also put a stop to new electric generating facilities being built to replace retiring ones despite the demand skyrocketing. What does the EPA's action mean for this law? Can it be repealed? Overturned in court? We sit down with analyst for the Thomas Jefferson Institute Steve Haner to find out. Learn more about your ad choices. Visit megaphone.fm/adchoices
The deconstruction of the Deep State Matrix begins as Trump finally gets his hands on the Holy Grail of evidence. Tulsi says the CIA's Project Mockingbird is still up and running? Why were child sex offenders flocking to America under Biden? (Please subscribe & share.) Sources: https://www.breitbart.com/politics/2025/07/29/poll-majority-oppose-local-authorities-in-sanctuary-cities-blocking-criminal-deportations/ https://nypost.com/2025/07/27/opinion/the-great-northeast-exodus-how-high-taxes-are-driving-away-billions/ https://www.wsj.com/business/ford-coors-gay-rights-index-dei-04c4ff94?reflink=desktopwebshare_permalink https://thehill.com/policy/international/5423711-trump-eu-trade-deal-tariffs-france/ https://nypost.com/2025/07/31/us-news/eric-adams-vetoes-city-councils-bid-to-decriminalize-illegal-vending-in-nyc/ https://www.foxnews.com/us/ice-arrests-over-200-illegal-alien-child-sex-offenders-houston-area-past-6-months?intcmp=tw_fnc&taid=6887a59e58ae3600011d3403&utm_campaign=trueanthem&utm_medium=social&utm_source=twitter https://newsbusters.org/blogs/nb/jorge-bonilla/2025/07/30/predictable-legacy-newscasts-omitted-fbi-russia-hoax-burn-bag https://newsbusters.org/blogs/nb/curtis-houck/2025/07/29/buried-nets-give-1000-times-more-coverage-russia-probe-gabbard https://libertywingspan.com/52879/uncategorized/operation-mockingbird/ https://redstate.com/smoosieq/2025/07/31/new-the-durham-annex-is-out-and-its-a-doozy-n2192305
Tonight... On the North American Friends Movie Club.A brave King. A dangerous quest. And some very wet squib work.We watched the 1975 British comedy film - Monty Python and the Holy Grail.So sharpen the spikes on your movie-watching mace.And bravely charge towards your couch.Because we're the kings of podcasts and your ears are our land. Hosted on Acast. See acast.com/privacy for more information.
Welcome to the BCJ Podcast, presented by BearcatJournal.com! This week Chad and David dive into what's been going on through three days at Camp Higher Ground. They follow that up with a discussion around what parity actually means for the Big 12 Conference, both good and bad. They wrap things up with a discussion around the dilemma of what and when to report around the mental health of student athletes. Visit the Holy Grail for a Cincy Light, with 50 cents per order supporting UC athletics! Turtle's Brew Time Stamps: 0:00 Camp Coverage on Day 3 1:04:00 How Good is Parity for the Big 12? 1:22:00 A Delicate Dance
Beer memorabilia collector Ken Hartoonian joins Herlinda Heras and Harry Duke in for Steve Jaxon on Brew Ha Ha today. At the Grange in Santa Rosa, Saturday Aug. 9, 9am-2pm, the Breweriana and Antique Advertising Show. It is a collection of brewery advertising apart from just cans but also lots of different kinds of promotional items. Grace Brothers brewers was a famous local brewery that was in operation from before Prohibition until 1962. Some of their cans are featured in the show. Ken has one of the most impressive collections of historic beer memorabilia and artefacts. He started when he was 12 years old, he loves sticker so he wrote to companies to ask for them. Then in 1975 the beer can collecting craze took hold. Before he knew it he had more than 100 cans. The closet grew into a storage unit and now he has a large metal barn. Here is a 30-second radio commercial from Grace Bros., with a swing band that was popular in those years. http://brewhaharadio.com/wp-content/uploads/2024/04/Grace_Bros_Beer_30_sec.mp3 Harry asks what is the Holy Grail of the items, or what is most significant to him? The Holy Grail would be a 7-11 beer can but the most significant was one that he traded for at about age 16. It was called Pride of Newark, or PON. Visit our sponsor Pizzaleah in Windsor for the finest pizza menu and the most authentic flavors around!
It can seem in 2025 like everyone in the ad ecosystem is chasing after the same Holy Grail: fast, rapidly delivered, personalized content at whatever scale they fancy. With the help of (yes) AI, it seems that dream is closer than ever. But is the business ready for it? Hosted on Acast. See acast.com/privacy for more information.
Willie talks with Jim Moering from the Holy Grail about the restaurant owners response to the violence downtown. Also Governor Mike DeWine weighs in. Finally Re Adam Bird explains why things need to change starting at the ballot box.
AlabamaSen. Britt says Dems spreading misinformation about GOP Medicaid changes2 state lawmakers pre file bill to offer death penalty in cases of child rapeState lawmaker files bill to prevent vaccine mandates by businesses in ALFarmPAC endorses Young Boozer in his re-election bid for state treasurerAn illegal alien on immigration hold, along with drug and stabbing charges9 dogs have been euthanized in Chilton county for attack that killed boyNationalNYC office shooting has 5 people dead including gunman, Shane TamuraUS AG Bondi files judicial conduct complain against Judge James BoasbergICE agents arrest Jamaican man working as police officer in state of MaineHouston ICE agents arrest over 200 illegal aliens who are child sex offendersUCLA agrees to $6.13M settlement for allowing antisemitic encampmentsEPA Director to end the "Holy Grail" of climate change: emissions regulationsHHS secretary makes big point on the increase in autism rates in USDouglass Mackey, "The Meme Guy" taking steps to countersue US government
From a gritty warlord in a chaotic Britain to a shining king in a legendary castle, the story of King Arthur has captivated the world for over 1,000 years. But how much of it is true? In this episode of English Plus, we pull the sword from the stone to separate the man from the myth. We're on a quest to answer the big questions: Who was the real historical figure that might have inspired the legend? How did French romance add Lancelot and the famous love triangle to the story? What is the true meaning of the Round Table, the Holy Grail, and the enigmatic wizard Merlin? Why does the dream of Camelot still hold such power over us today? This episode is also your key to more sophisticated English. We break down 10 essential words and phrases like "archetype," "chivalry," "anachronism," and "utopian" to elevate your vocabulary. Plus, a special speaking lesson on using narrative structure will help you tell more compelling stories in your own life. Join us for a journey into the heart of history, myth, and legend. To unlock full access to all our episodes, consider becoming a premium subscriber on Apple Podcasts or Patreon. And don't forget to visit englishpluspodcast.com for even more content, including articles, in-depth studies, and our brand-new audio series and courses now available in our Patreon Shop!
Willie talks with Jim Moering from the Holy Grail about the restaurant owners response to the violence downtown. Also Governor Mike DeWine weighs in. Finally Re Adam Bird explains why things need to change starting at the ballot box.
Willie talks with Jim Moering from the Holy Grail about the restaurant owners response to the violence downtown. Also Governor Mike DeWine weighs in. Finally Re Adam Bird explains why things need to change starting at the ballot box.
The 3M Open was a birdie fire sale as everyone went low, low, low. The ISPS Handa Senior Open was another major victory for Padraig Harrington, who is making a case for Player of the Year. The ISPS Handa Women's Scottish Open featured a win for the newly turned pro Lottia Woad, who is also now the favorite for this week's Open Championship. Past guest Mia Hammond, known for dropping out of school at 16 to go pro, got her first win this week on the Epson Tour. Alex got to play one of the Holy Grails of golf last week, Payne's Valley at Big Cedar Lodge. He shares what made it so great, and where it ranks in his list of amazing courses. In Tuned In, Michael and Alex share their reviews of Happy Gilmore 2, and Michael was not a fan. This week's guest is Megan Johnston, returning to the podcast as Alex chats with her from Big Cedar Lodge. The golf instructor, named as one of the country's best by Golf Digest and the LPGA, shares what drew her to Big Cedar Lodge and what makes the Ozarks such an amazing part of the country. The NFL Preseason is now upon us, as football games start up on Thursday. So Alex is, as always, overwhelmed with excitement. As the guys #AlwaysEndWithFood, Alex shares his excitement for all the pizza he'll be eating in the Chicago area this next week, and Michael shares a glowing review of Eden Supper Club in Savannah. Learn more about your ad choices. Visit megaphone.fm/adchoices
Join Chad Brendel and David Simone for the BCJ Podcast, presented by Holy Grail live from the Cincy Light Studios! This week they bring on BCJ's own Keegan Nickoson and start the show off discussing a full camp preview as the team prepares to invade Camp Higher Ground next week. The follow that up with a long discussion of preseason spotlights, focusing on players that may not necessarily be on your radar yet. Stop by Holy Grail for great food, drinks, and ice-cold Cincy Light—50 cents from every purchase supports UC athletes! Join the conversation live every Wednesday night at 8pm on the Bearcat Journal Twitch and YouTube channels, and don't forget to like and subscribe while you're there! Turtle's Brew Time Stamps 0:00 - 58:00 Camp Preview 58:00 - 1:52:02 Preseason Spotlights
The Jesus bloodline refers to the proposition that a lineal sequence of the historical Jesus has persisted, possibly to the present time. Although absent from the Gospels or historical records, the concept of Jesus having descendants has gained a presence in the public imagination, as seen with Holy Blood, Holy Grail a book by Michael Baigent, Richard Leigh, and Henry Lincoln and Dan Brown's 2003 best-selling novel The Da Vinci Code. These claimed Jesus's bloodlines are distinct from the biblical genealogy of Jesus, which concerns the ancestors of Jesus, and from the alleged Brothers of Jesus and other kin of Jesus, known as the Desposyni. In the final chapter of Joel's intricate look at the supposed bloodlines of Jesus, Joel explores the Lost Tomb of Jesus and if there is any validity to the claims of the documentary. He shines a light on Simcha Jacovici's claims that the ossuaries found in the Talpiot Tomb are of Jesus and His family. He also looks at the idea that Jesus is of an alien race which are the creators of the Rh-Negative bloodline. Lastly, Joel speculates on where the Rex Deus genealogies actually come from and what it means for our possible future. The Meadow Project Film Tickets: https://www.moment.co/themeadowproject Free The Rabbits Merch: https://freetherabbits.myshopify.com Buy Me A Coffee: Donate Website: https://linktr.ee/joelthomasmedia Follow: Instagram | X | Facebook Watch: YouTube | Rumble Music: YouTube | Spotify | Apple Music Films: merkelfilms.com Email: freetherabbitspodcast@gmail.com Distributed by: merkel.media Produced by: @jack_theproducer INTRO MUSIC Joel Thomas - Free The Rabbits YouTube | Apple Music | Spotify OUTRO MUSIC Joel Thomas - Imposter YouTube | Apple Music | Spotify
1989 was what some might call a good year for movies. The top-grossing films could easily be mistaken for anyone's favorite 80s movies list: Batman, Lethal Weapon 2, Rain Man, Ghostbusters II. You might even consider including Tango & Cash. But only one 1989 release brought back the iconic bullwhip and fedora.Indiana Jones returned to the big screen in a blockbuster adventure full of humor, heart, and incredible stunts. Set in 1938, our hero embarks on a mission to rescue his father, a medievalist who has disappeared while searching for the Holy Grail. Following clues in Henry Sr.'s cherished notebook, Indy travels to Europe, reuniting with old allies while battling new Nazi enemies.So, dust off your fedora, crack the bullwhip, and take a leap of faith with Tim Williams and guest co-hosts, Gerry D, Nicholas Pepin, and Chad Sheppard as they discuss “Indiana Jones and the Last Crusade” on this episode of the 80s Flick Flashback Podcast!Here are some additional behind-the-scenes trivia we were unable to cover in this episode:When Henry expresses surprise that Indy can fly a plane, Indiana responds with "Fly, yes. Land, no." This references his crashing a plane in "Indiana Jones and the Temple of Doom" (1984).Henry Sr. and Jr. point out that in Latin, Jehovah starts with an I, not a J. This is accurate, especially considering that the knight who recovered the Grail did so during the First Crusade. The First Crusade ended in 1099. During the Roman Empire, J was just a variation of an I, which is why their lowercase forms, i and j, look similar. The original pronunciation was very much like an I or Y. Its use as a soft 'g' sound did not appear before the 15th century.Sources:Wikipedia, IMDB, BoxOfficeMojohttps://www.shortlist.com/news/15-things-you-probably-didnt-know-about-indiana-jones-and-the-last-crusadeSome sections were composed by ChatGPTWe'd love to hear your thoughts on our podcast! You can share your feedback with us via email or social media.Website - https://www.80sflickflashback.com/TeePublic Store - https://www.teepublic.com/user/eighties-flick-flashbackBuy Me A Coffee - https://buymeacoffee.com/80sflickfbFacebook - https://www.facebook.com/80sflickflashbackpodcastInstagram - https://www.instagram.com/80sflickflashback/TikTok - https://www.tiktok.com/@80sflickflashbackEmail - Info@80sFlickFlashback.com
Chad Brendel and David Simone discuss the week that was Cincinnati Bearcats live from the Cincy Light Studios. They kick the show off with special guest Offensive Line Coach Nic Cardwell, before moving to football notes and loose ends. They wrap up the show with a discussion on the men's basketball media availability today, and a rant by David about Home Run Hitter Mardy Gilyard. Join the conversation live every Wednesday night at 8pm on the Bearcat Journal Twitch and YouTube channels, and don't forget to like and subscribe while you're there! Turtle's Brew Time Stamps 0:00 - 49:00 Offensive Line Coach Nic Cardwell 49:00 - 1:15:00 Football Notes and Loose Ends 1:15:00 - 1:37:16 Men's Basketball Media Availability
Meinen Fachleute eine bedeutende Beobachtung gemacht zu haben, sprechen sie manchmal vom "Heiligen Gral", den sie aufgespürt hätten. Ob Schwefelverbindungen, kosmische Hintergrundstrahlung oder vermisster Asteroid: der Heilige Gral ist sehr vielfältig! Lorenzen, Dirk www.deutschlandfunk.de, Sternzeit
Send us a textMike Munger explores how Monty Python brilliantly illustrated transaction cost economics through their legendary comedy sketches. The British comedy troupe's most famous routines provide perfect, hilarious examples of the frictions that make economic interactions costly and complicated in the real world.• Three definitions of transaction costs from Ronald Coase, Douglas North, and Oliver Williamson• The Dead Parrot sketch as an illustration of ex-post recontracting problems and contract enforcement• Ministry of Silly Walks demonstrating how inefficient institutions persist due to high reform costs• The Argument Clinic depicting problems with contract scope and definition• Monty Python and the Holy Grail showing barriers to entry and communication costs• Spanish Inquisition sketch revealing coordination failuresThe five MP sketches mentioned here:Dead Parrot Sketch: https://youtu.be/4vuW6tQ0218?si=hHfu07sgQeCgxUxx Ministry of Silly Walks: https://youtu.be/iV2ViNJFZC8?si=U5QxzDeYXeT3UhIq Argument Clinic: https://youtu.be/uLlv_aZjHXc?si=aU14dFjwnJeDvRf7 Holy Grail—Anarcho-Syndicalist Peasant: https://youtu.be/_EMZ1u__LUc?si=C9z8e4NAQDRkU8q7 Spanish Inquisition: https://www.youtube.com/watch?v=D5Df191WJ3o Letter: Swiss Air's efficient window-seat-first boarding policyBook'o'da'week: To Overthrow the World: The Rise and Fall and Rise of Communism, by Sean McMeekinNext episode releases July 22nd, beginning the co-produced series on Adam Smith's "Wealth of Nations" with an overview of the Scottish Enlightenment.If you have questions or comments, or want to suggest a future topic, email the show at taitc.email@gmail.com ! You can follow Mike Munger on Twitter at @mungowitz
The Jesus bloodline refers to the proposition that a lineal sequence of the historical Jesus has persisted, possibly to the present time. Although absent from the Gospels or historical records, the concept of Jesus having descendants has gained a presence in the public imagination, as seen with Holy Blood, Holy Grail a book by Michael Baigent, Richard Leigh, and Henry Lincoln and Dan Brown's 2003 best-selling novel The Da Vinci Code. These claimed Jesus's bloodlines are distinct from the biblical genealogy of Jesus, which concerns the ancestors of Jesus, and from the alleged Brothers of Jesus and other kin of Jesus, known as the Desposyni. Joel dives even deeper into the supposed hidden bloodlines of Jesus with a look at who Joseph of Arimathea was historically. He sets his focus on the gnostic Essene version of Joseph and the idea he was actually James the Just, brother of Jesus. He then looks at the Tribe of Scota and how it spawned from ancient Egypt into Ireland and Scottland from Israeli descent and possibly intermingling with the Tuatha De Danann. Lastly, Joel walks through the Fisher Kings, the Merovingians, whose rise to the top was swift and seemingly out of nowhere, but how it makes sense considering the represented the most secretive bloodline in the history of the earth. The Meadow Project Film Tickets: https://www.moment.co/themeadowproject Free The Rabbits Merch: https://freetherabbits.myshopify.com Buy Me A Coffee: Donate Website: https://linktr.ee/joelthomasmedia Follow: Instagram | X | Facebook Watch: YouTube | Rumble Music: YouTube | Spotify | Apple Music Films: merkelfilms.com Email: freetherabbitspodcast@gmail.com Distributed by: merkel.media Produced by: @jack_theproducer INTRO MUSIC Joel Thomas - Free The Rabbits YouTube | Apple Music | Spotify OUTRO MUSIC Joel Thomas - Imposter YouTube | Apple Music | Spotify
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Steve is joined again by Pastors Eric and Justin from Sound the Shofar Messianic Ministries. In the first hour, we discuss the myths and legends surrounding the Holy Grail. Find Sound the Shofar Messianic Ministries online: https://www.facebook.com/groups/123168699032724Become a supporter of this podcast: https://www.spreaker.com/podcast/missing-persons-mysteries--5624803/support.
Chad Brendel and David Simone discuss the week that was Cincinnati Bearcats live from the Cincy Light Studios. They begin the show discussing the chatter from some little birdies that had information from hoops practice. They finish the show with a check in from Keegan Nickoson as he attends Big 12 Media Days. Join the conversation live every Wednesday night at 8pm on the Bearcat Journal Twitch and YouTube channels, and don't forget to like and subscribe while you're there! Turtle's Brew Time Stamps 0:00 - 1:00:00 Warblers Are A-Warblin' 1:00:00 - 1:38:05 Big 12 Media Days
Dr. Paul Hanona and Dr. Arturo Loaiza-Bonilla discuss how to safely and smartly integrate AI into the clinical workflow and tap its potential to improve patient-centered care, drug development, and access to clinical trials. TRANSCRIPT Dr. Paul Hanona: Hello, I'm Dr. Paul Hanona, your guest host of the ASCO Daily News Podcast today. I am a medical oncologist as well as a content creator @DoctorDiscover, and I'm delighted to be joined today by Dr. Arturo Loaiza-Bonilla, the chief of hematology and oncology at St. Luke's University Health Network. Dr. Bonilla is also the co-founder and chief medical officer at Massive Bio, an AI-driven platform that matches patients with clinical trials and novel therapies. Dr. Loaiza-Bonilla will share his unique perspective on the potential of artificial intelligence to advance precision oncology, especially through clinical trials and research, and other key advancements in AI that are transforming the oncology field. Our full disclosures are available in the transcript of the episode. Dr. Bonilla, it's great to be speaking with you today. Thanks for being here. Dr. Arturo Loaiza-Bonilla: Oh, thank you so much, Dr. Hanona. Paul, it's always great to have a conversation. Looking forward to a great one today. Dr. Paul Hanona: Absolutely. Let's just jump right into it. Let's talk about the way that we see AI being embedded in our clinical workflow as oncologists. What are some practical ways to use AI? Dr. Arturo Loaiza-Bonilla: To me, responsible AI integration in oncology is one of those that's focused on one principle to me, which is clinical purpose is first, instead of the algorithm or whatever technology we're going to be using. If we look at the best models in the world, they're really irrelevant unless we really solve a real day-to-day challenge, either when we're talking to patients in the clinic or in the infusion chair or making decision support. Currently, what I'm doing the most is focusing on solutions that are saving us time to be more productive and spend more time with our patients. So, for example, we're using ambient AI for appropriate documentation in real time with our patients. We're leveraging certain tools to assess for potential admission or readmission of patients who have certain conditions as well. And it's all about combining the listening of physicians like ourselves who are end users, those who create those algorithms, data scientists, and patient advocates, and even regulators, before they even write any single line of code. I felt that on my own, you know, entrepreneurial aspects, but I think it's an ethos that we should all follow. And I think that AI shouldn't be just bolted on later. We always have to look at workflows and try to look, for example, at clinical trial matching, which is something I'm very passionate about. We need to make sure that first, it's easier to access for patients, that oncologists like myself can go into the interface and be able to pull the data in real time when you really need it, and you don't get all this fatigue alerts. To me, that's the responsible way of doing so. Those are like the opportunities, right? So, the challenge is how we can make this happen in a meaningful way – we're just not reacting to like a black box suggestion or something that we have no idea why it came up to be. So, in terms of success – and I can tell you probably two stories of things that we know we're seeing successful – we all work closely with radiation oncologists, right? So, there are now these tools, for example, of automated contouring in radiation oncology, and some of these solutions were brought up in different meetings, including the last ASCO meeting. But overall, we know that transformer-based segmentation tools; transformer is just the specific architecture of the machine learning algorithm that has been able to dramatically reduce the time for colleagues to spend allotting targets for radiation oncology. So, comparing the target versus the normal tissue, which sometimes it takes many hours, now we can optimize things over 60%, sometimes even in minutes. So, this is not just responsible, but it's also an efficiency win, it's a precision win, and we're using it to adapt even mid-course in response to tumor shrinkage. Another success that I think is relevant is, for example, on the clinical trial matching side. We've been working on that and, you know, I don't want to preach to the choir here, but having the ability for us to structure data in real time using these tools, being able to extract information on biomarkers, and then show that multi-agentic AI is superior to what we call zero-shot or just throwing it into ChatGPT or any other algorithm, but using the same tools but just fine-tuned to the point that we can be very efficient and actually reliable to the level of almost like a research coordinator, is not just theory. Now, it can change lives because we can get patients enrolled in clinical trials and be activated in different places wherever the patient may be. I know it's like a long answer on that, but, you know, as we talk about responsible AI, that's important. And in terms of what keeps me up at night on this: data drift and biases, right? So, imaging protocols, all these things change, the lab switch between different vendors, or a patient has issues with new emerging data points. And health systems serve vastly different populations. So, if our models are trained in one context and deployed in another, then the output can be really inaccurate. So, the idea is to become a collaborative approach where we can use federated learning and patient-centricity so we can be much more efficient in developing those models that account for all the populations, and any retraining that is used based on data can be diverse enough that it represents all of us and we can be treated in a very good, appropriate way. So, if a clinician doesn't understand why a recommendation is made, as you probably know, you probably don't trust it, and we shouldn't expect them to. So, I think this is the next wave of the future. We need to make sure that we account for all those things. Dr. Paul Hanona: Absolutely. And even the part about the clinical trials, I want to dive a little bit more into in a few questions. I just kind of wanted to make a quick comment. Like you said, some of the prevalent things that I see are the ambient scribes. It seems like that's really taken off in the last year, and it seems like it's improving at a pretty dramatic speed as well. I wonder how quickly that'll get adopted by the majority of physicians or practitioners in general throughout the country. And you also mentioned things with AI tools regarding helping regulators move things quicker, even the radiation oncologist, helping them in their workflow with contouring and what else they might have to do. And again, the clinical trials thing will be quite interesting to get into. The first question I had subsequent to that is just more so when you have large datasets. And this pertains to two things: the paper that you published recently regarding different ways to use AI in the space of oncology referred to drug development, the way that we look at how we design drugs, specifically anticancer drugs, is pretty cumbersome. The steps that you have to take to design something, to make sure that one chemical will fit into the right chemical or the structure of the molecule, that takes a lot of time to tinker with. What are your thoughts on AI tools to help accelerate drug development? Dr. Arturo Loaiza-Bonilla: Yes, that's the Holy Grail and something that I feel we should dedicate as much time and effort as possible because it relies on multimodality. It cannot be solved by just looking at patient histories. It cannot be solved by just looking at the tissue alone. It's combining all these different datasets and being able to understand the microenvironment, the patient condition and prior treatments, and how dynamic changes that we do through interventions and also exposome – the things that happen outside of the patient's own control – can be leveraged to determine like what's the best next step in terms of drugs. So, the ones that we heard the news the most is, for example, the Nobel Prize-winning [for Chemistry awarded to Demis Hassabis and John Jumper for] AlphaFold, an AI system that predicts protein structures right? So, we solved this very interesting concept of protein folding where, in the past, it would take the history of the known universe, basically – what's called the Levinthal's paradox – to be able to just predict on amino acid structure alone or the sequence alone, the way that three-dimensionally the proteins will fold. So, with that problem being solved and the Nobel Prize being won, the next step is, “Okay, now we know how this protein is there and just by sequence, how can we really understand any new drug that can be used as a candidate and leverage all the data that has been done for many years of testing against a specific protein or a specific gene or knockouts and what not?” So, this is the future of oncology and where we're probably seeing a lot of investments on that. The key challenge here is mostly working on the side of not just looking at pathology, but leveraging this digital pathology with whole slide imaging and identifying the microenvironment of that specific tissue. There's a number of efforts currently being done. One isn't just H&E, like hematoxylin and eosin, slides alone, but with whole imaging, now we can use expression profiles, spatial transcriptomics, and gene whole exome sequencing in the same space and use this transformer technology in a multimodality approach that we know already the slide or the pathology, but can we use that to understand, like, if I knock out this gene, how is the microenvironment going to change to see if an immunotherapy may work better, right? If we can make a microenvironment more reactive towards a cytotoxic T cell profile, for example. So, that is the way where we're really seeing the field moving forward, using multimodality for drug discovery. So, the FDA now seems to be very eager to support those initiatives, so that's of course welcome. And now the key thing is the investment to do this in a meaningful way so we can see those candidates that we're seeing from different companies now being leveraged for rare disease, for things that are going to be almost impossible to collect enough data, and make it efficient by using these algorithms that sometimes, just with multiple masking – basically, what they do is they mask all the features and force the algorithm to find solutions based on the specific inputs or prompts we're doing. So, I'm very excited about that, and I think we're going to be seeing that in the future. Dr. Paul Hanona: So, essentially, in a nutshell, we're saying we have the cancer, which is maybe a dandelion in a field of grass, and we want to see the grass that's surrounding the dandelion, which is the pathology slides. The problem is, to the human eye, it's almost impossible to look at every single piece of grass that's surrounding the dandelion. And so, with tools like AI, we can greatly accelerate our study of the microenvironment or the grass that's surrounding the dandelion and better tailor therapy, come up with therapy. Otherwise, like you said, to truly generate a drug, this would take years and years. We just don't have the throughput to get to answers like that unless we have something like AI to help us. Dr. Arturo Loaiza-Bonilla: Correct. Dr. Paul Hanona: And then, clinical trials. Now, this is an interesting conversation because if you ever look up our national guidelines as oncologists, there's always a mention of, if treatment fails, consider clinical trials. Or in the really aggressive cancers, sometimes you might just start out with clinical trials. You don't even give the standard first-line therapy because of how ineffective it is. There are a few issues with clinical trials that people might not be aware of, but the fact that the majority of patients who should be on clinical trials are never given the chance to be on clinical trials, whether that's because of proximity, right, they might live somewhere that's far from the institution, or for whatever reason, they don't qualify for the clinical trial, they don't meet the strict inclusion criteria. But a reason you mentioned early on is that it's simply impossible for someone to be aware of every single clinical trial that's out there. And then even if you are aware of those clinical trials, to actually find the sites and put in the time could take hours. And so, how is AI going to revolutionize that? Because in my mind, it's not that we're inventing a new tool. Clinical trials have always been available. We just can't access them. So, if we have a tool that helps with access, wouldn't that be huge? Dr. Arturo Loaiza-Bonilla: Correct. And that has been one of my passions. And for those who know me and follow me and we've spoke about it in different settings, that's something that I think we can solve. This other paradox, which is the clinical trial enrollment paradox, right? We have tens of thousands of clinical trials available with millions of patients eager to learn about trials, but we don't enroll enough and many trials close to accrual because of lack of enrollment. It is completely paradoxical and it's because of that misalignment because patients don't know where to go for trials and sites don't know what patients they can help because they haven't reached their doors yet. So, the solution has to be patient-centric, right? We have to put the patient at the center of the equation. And that was precisely what we had been discussing during the ASCO meeting. There was an ASCO Education Session where we talked about digital prescreening hubs, where we, in a patient-centric manner, the same way we look for Uber, Instacart, any solution that you may think of that you want something that can be leveraged in real time, we can use these real-world data streams from the patient directly, from hospitals, from pathology labs, from genomics companies, to continuously screen patients who can match to the inclusion/exclusion criteria of unique trials. So, when the patient walks into the clinic, the system already knows if there's a trial and alerts the site proactively. The patient can actually also do decentralization. So, there's a number of decentralized clinical trial solutions that are using what I call the “click and mortar” approach, which is basically the patient is checking digitally and then goes to the site to activate. We can also have the click and mortar in the bidirectional way where the patient is engaged in person and then you give the solution like the ones that are being offered on things that we're doing at Massive Bio and beyond, which is having the patient to access all that information and then they make decisions and enroll when the time is right. As I mentioned earlier, there is this concept drift where clinical trials open and close, the patient line of therapy changes, new approvals come in and out, and sites may not be available at a given time but may be later. So, having that real-time alerts using tools that are able already to extract data from summarization that we already have in different settings and doing this natural language ingestion, we can not only solve this issue with manual chart review, which is extremely cumbersome and takes forever and takes to a lot of one-time assessments with very high screen failures, to a real-time dynamic approach where the patient, as they get closer to that eligibility criteria, they get engaged. And those tools can be built to activate trials, audit trials, and make them better and accessible to patients. And something that we know is, for example, 91%-plus of Americans live close to either a pharmacy or an imaging center. So, imagine that we can potentially activate certain of those trials in those locations. So, there's a number of pharmacies, special pharmacies, Walgreens, and sometimes CVS trying to do some of those efforts. So, I think the sky's the limit in terms of us working together. And we've been talking with corporate groups, they're all interested in those efforts as well, to getting patients digitally enabled and then activate the same way we activate the NCTN network of the corporate groups, that are almost just-in-time. You can activate a trial the patient is eligible for and we get all these breakthroughs from the NIH and NCI, just activate it in my site within a week or so, as long as we have the understanding of the protocol. So, using clinical trial matching in a digitally enabled way and then activate in that same fashion, but not only for NCTN studies, but all the studies that we have available will be the key of the future through those prescreening hubs. So, I think now we're at this very important time where collaboration is the important part and having this silo-breaking approach with interoperability where we can leverage data from any data source and from any electronic medical records and whatnot is going to be essential for us to move forward because now we have the tools to do so with our phones, with our interests, and with the multiple clinical trials that are coming into the pipelines. Dr. Paul Hanona: I just want to point out that the way you described the process involves several variables that practitioners often don't think about. We don't realize the 15 steps that are happening in the background. But just as a clarifier, how much time is it taking now to get one patient enrolled on a clinical trial? Is it on the order of maybe 5 to 10 hours for one patient by the time the manual chart review happens, by the time the matching happens, the calls go out, the sign-up, all this? And how much time do you think a tool that could match those trials quicker and get you enrolled quicker could save? Would it be maybe an hour instead of 15 hours? What's your thought process on that? Dr. Arturo Loaiza-Bonilla: Yeah, exactly. So one is the matching, the other one is the enrollment, which, as you mentioned, is very important. So, it can take, from, as you said, probably between 4 days to sometimes 30 days. Sometimes that's how long it takes for all the things to be parsed out in terms of logistics and things that could be done now agentically. So, we can use agents to solve those different steps that may take multiple individuals. We can just do it as a supply chain approach where all those different steps can be done by a single agent in a simultaneous fashion and then we can get things much faster. With an AI-based solution using these frontier models and multi-agentic AI – and we presented some of this data in ASCO as well – you can do 5,000 patients in an hour, right? So, just enrolling is going to be between an hour and maximum enrollment, it could be 7 days for those 5,000 patients if it was done at scale in a multi-level approach where we have all the trials available. Dr. Paul Hanona: No, definitely a very exciting aspect of our future as oncologists. It's one thing to have really neat, novel mechanisms of treatment, but what good is it if we can't actually get it to people who need it? I'm very much looking for the future of that. One of the last questions I want to ask you is another prevalent way that people use AI is just simply looking up questions, right? So, traditionally, the workflow for oncologists is maybe going on national guidelines and looking up the stage of the cancer and seeing what treatments are available and then referencing the papers and looking at who was included, who wasn't included, the side effects to be aware of, and sort of coming up with a decision as to how to treat a cancer patient. But now, just in the last few years, we've had several tools become available that make getting questions easier, make getting answers easier, whether that's something like OpenAI's tools or Perplexity or Doximity or OpenEvidence or even ASCO has a Guidelines Assistant as well that is drawing from their own guidelines as to how to treat different cancers. Do you see these replacing traditional sources? Do you see them saving us a lot more time so that we can be more productive in clinic? What do you think is the role that they're going to play with patient care? Dr. Arturo Loaiza-Bonilla: Such a relevant question, particularly at this time, because these AI-enabled query tools, they're coming left and right and becoming increasingly common in our daily workflows and things that we're doing. So, traditionally, when we go and we look for national guidelines, we try to understand the context ourselves and then we make treatment decisions accordingly. But that is a lot of a process that now AI is helping us to solve. So, at face value, it seems like an efficiency win, but in many cases, I personally evaluate platforms as the chief of hem/onc at St. Luke's and also having led the digital engagement things through Massive Bio and trying to put things together, I can tell you this: not all tools are created equal. In cancer care, each data point can mean the difference between cure and progression, so we cannot really take a lot of shortcuts in this case or have unverified output. So, the tools are helpful, but it has to be grounded in truth, in trusted data sources, and they need to be continuously updated with, like, ASCO and NCCN and others. So, the reason why the ASCO Guidelines Assistant, for instance, works is because it builds on all these recommendations, is assessed by end users like ourselves. So, that kind of verification is critical, right? We're entering a phase where even the source material may be AI-generated. So, the role of human expert validation is really actually more important, not less important. You know, generalist LLMs, even when fine-tuned, they may not be enough. You can pull a few API calls from PubMed, etc., but what we need now is specialized, context-aware, agentic tools that can interpret multimodal and real-time clinical inputs. So, something that we are continuing to check on and very relevant to have entities and bodies like ASCO looking into this so they can help us to be really efficient and really help our patients. Dr. Paul Hanona: Dr. Bonilla, what do you want to leave the listener with in terms of the future direction of AI, things that we should be cautious about, and things that we should be optimistic about? Dr. Arturo Loaiza-Bonilla: Looking 5 years ahead, I think there's enormous promise. As you know, I'm an AI enthusiast, but always, there's a few priorities that I think – 3 of them, I think – we need to tackle head-on. First is algorithmic equity. So, most AI tools today are trained on data from academic medical centers but not necessarily from community practices or underrepresented populations, particularly when you're looking at radiology, pathology, and what not. So, those blind spots, they need to be filled, and we can eliminate a lot of disparities in cancer care. So, those frameworks to incentivize while keeping the data sharing using federated models and things that we can optimize is key. The second one is the governance on the lifecycle. So, you know, AI is not really static. So, unlike a drug that is approved and it just, you know, works always, AI changes. So, we need to make sure that we have tools that are able to retrain and recall when things degrade or models drift. So, we need to use up-to-date AI for clinical practice, so we are going to be in constant revalidation and make it really easy to do. And lastly, the human-AI interface. You know, clinicians don't need more noise or we don't need more black boxes. We need decision support that is clear, that we can interpret, and that is actionable. “Why are you using this? Why did we choose this drug? Why this dose? Why now?” So, all these things are going to help us and that allows us to trace evidence with a single click. So, I always call it back to the Moravec's paradox where we say, you know, evolution gave us so much energy to discern in the sensory-neural and dexterity. That's what we're going to be taking care of patients. We can use AI to really be a force to help us to be better clinicians and not to really replace us. So, if we get this right and we decide for transparency with trust, inclusion, etc., it will never replace any of our work, which is so important, as much as we want, we can actually take care of patients and be personalized, timely, and equitable. So, all those things are what get me excited every single day about these conversations on AI. Dr. Paul Hanona: All great thoughts, Dr. Bonilla. I'm very excited to see how this field evolves. I'm excited to see how oncologists really come to this field. I think with technology, there's always a bit of a lag in adopting it, but I think if we jump on board and grow with it, we can do amazing things for the field of oncology in general. Thank you for the advancements that you've made in your own career in the field of AI and oncology and just ultimately with the hopeful outcomes of improving patient care, especially cancer patients. Dr. Arturo Loaiza-Bonilla: Thank you so much, Dr. Hanona. Dr. Paul Hanona: Thanks to our listeners for your time today. If you value the insights that you hear on ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. More on today's speakers: Dr. Arturo Loaiza-Bonilla @DrBonillaOnc Dr. Paul Hanona @DoctorDiscover on YouTube Follow ASCO on social media: @ASCO on Twitter ASCO on Facebook ASCO on LinkedIn ASCO on BlueSky Disclosures: Paul Hanona: No relationships to disclose. Dr. Arturo-Loaiza-Bonilla: Leadership: Massive Bio Stock & Other Ownership Interests: Massive Bio Consulting or Advisory Role: Massive Bio, Bayer, PSI, BrightInsight, CardinalHealth, Pfizer, AstraZeneca, Medscape Speakers' Bureau: Guardant Health, Ipsen, AstraZeneca/Daiichi Sankyo, Natera
The Jesus bloodline refers to the proposition that a lineal sequence of the historical Jesus has persisted, possibly to the present time. Although absent from the Gospels or historical records, the concept of Jesus having descendants has gained a presence in the public imagination, as seen with Holy Blood, Holy Grail a book by Michael Baigent, Richard Leigh, and Henry Lincoln and Dan Brown's 2003 best-selling novel The Da Vinci Code. These claimed Jesus's bloodlines are distinct from the biblical genealogy of Jesus, which concerns the ancestors of Jesus, and from the alleged Brothers of Jesus and other kin of Jesus, known as the Desposyni. Joel continues to peel back the layers shrouding the mystery of the supposed Bloodlines of Jesus Christ. He looks at the origins of the Knights Templar and how their roots go back to not only the Priory of Sion but Rex Deus and the Essenes. He then takes a look at the hidden relationship between the Templars and the Islamic Assassins and how they both professed outwardly their devotion to Christianity and Islam but secretly practiced esoteric Gnosticism coupled with devotion to hiding hidden bloodlines. He also peers into Rosslyn Chapel, the secrets it holds, including Freemasonic treasures along with the Holy Grail. Finally, Joel lays out the Gnostic blueprint for hiding the genealogy of Jesus and Mary Magdalene and what became of their purported children. Buy Me A Coffee: Donate Website: https://linktr.ee/joelthomasmedia Follow: Instagram | X | Facebook Watch: YouTube | Rumble Music: YouTube | Spotify | Apple Music Films: merkelfilms.com Email: freetherabbitspodcast@gmail.com Distributed by: merkel.media Produced by: @jack_theproducer INTRO MUSIC Joel Thomas - Free The Rabbits YouTube | Apple Music | Spotify OUTRO MUSIC Joel Thomas - Imposter YouTube | Apple Music | Spotify
'Tis but a scratch! This week on Cocktails & Classics, we embark on a ridiculous quest with the legendary 1975 comedy, "Monty Python and the Holy Grail." Join us as we laugh our way through King Arthur's absurd journey, killer bunnies, and insulting Frenchmen. We'll dissect the film's unique comedic style, its quotable lines, and its enduring influence on pop culture. Feeling silly? Craft a classic cocktail while you listen! Don't miss this episode for a hilarious deep dive into a timeless comedic masterpiece, fueled by classic cocktails and gloriously silly discussions.Monty Python's Unique Humor: Analyze the distinct comedic style of the Monty Python troupe, including surrealism, silliness, satire, and breaking the fourth wall.Pop Culture Impact: From memorable characters and infinitely quotable lines, we take a look at how the film has permeated pop culture. Low-Budget Brilliance: We discuss how the film's constrained budget led to creative and iconic comedic choices (e.g., coconuts for horses & multiple roles for actors).Thematically, What is it About? Beyond the laughs, is there any underlying commentary or message? (e.g., quest for meaning, absurdity of life, class critique).What's your favorite "Monty Python and the Holy Grail" quote or absurdist moment? Share your thoughts and funniest film experiences on Instagram! #CocktailsAndClassics Don't forget to share this hilariously absurd episode with your friends and family! Subscribe and leave a rating wherever you listen.
Chad Brendel and David Simone discuss the week that was Cincinnati Bearcats live from the Cincy Light Studios. They kick off the show with the Chief Creative Officer of the University of Cincinnati, Dan Phillips, to discuss today's unveiling of the new jerseys for the Bearcats football team. They follow that up with a look around the Big 12 Conference with Brien Hanley of Big 12 Insiders. They cap things off putting a bow on the conference talk with a look ahead to Big 12 Media Days. Join the conversation live every Wednesday night at 8pm on the Bearcat Journal Twitch and YouTube channels, and don't forget to like and subscribe while you're there! Turtle's Brew Time Stamps 0:00 - 30:00 Chief Creative Officer Dan Phillips 30:00 - 1:15:00 Brien Hanley of Big 12 Insiders 1:15:00 - 1:35:29 Big 12 Media Days
Welcome to the second episode of The Holy Grail of Investing podcast! In this fascinating conversation, my co-hosts ChristopherZook and Mark Wade of CAZ Investments, sit down with Michael Rees, Co-President of Blue Owl Capital to unpack the asset class known as GP Stakes. This strategy has grown geometrically over the past decade and is rapidly becoming one of the more coveted strategies among the world's most sophisticated investors who want broad exposure to Private Equity. Watch this episode now on YouTube at @TonyRobbinsLive Learn more at www.TheHolyGrailofInvesting.com and www.CAZInvestments.com "The Holy Grail of Investing podcast is about more than just investing—it's about giving listeners a front-row seat to how some of the world's greatest investors think,” said Tony Robbins. “These conversations usually happen behind closed doors, and now we are making them available to a much broader audience—even those just starting to explore private market opportunities.” Hosted by Tony Robbins and investor Christopher Zook, this new podcast offers rare, behind-the-scenes conversations with legendary private market investors—exploring not just how they invest, but why they do what they do.
These lectures will explore two Arthurian romances, Chretien de Troyes' Knight of the Cart, and the Cistercian text we know as The Quest of the Holy Grail, through the lens of Catholic teaching on redemption, divine grace, and the pursuit of virtue.
The Jesus bloodline refers to the proposition that a lineal sequence of the historical Jesus has persisted, possibly to the present time. Although absent from the Gospels or historical records, the concept of Jesus having descendants has gained a presence in the public imagination, as seen with Holy Blood, Holy Grail a book by Michael Baigent, Richard Leigh, and Henry Lincoln and Dan Brown's 2003 best-selling novel The Da Vinci Code. These claimed Jesus's bloodlines are distinct from the biblical genealogy of Jesus, which concerns the ancestors of Jesus, and from the alleged Brothers of Jesus and other kin of Jesus, known as the Desposyni. Walk with Joel as he digs through a mountain of secret societies, gnostic sects and proposed genealogies to uncover the truth of these so-called "hidden" bloodlines of Jesus. He looks at the Desposyni vs. Rex Deus and if there is any correlation between the two. He then uncovers the Rennes-le-Château, Father Bérenger Saunière and the secrets they both were said to possess. Lastly, Joel looks at the mysterious Priory of Sion and the supposed hoaxer, Pierre Plantard, who was behind it and if the list of masters were indeed hiding Merivingian bloodlines. Buy Me A Coffee: Donate Website: https://linktr.ee/joelthomasmedia Follow: Instagram | X | Facebook Watch: YouTube | Rumble Music: YouTube | Spotify | Apple Music Films: merkelfilms.com Email: freetherabbitspodcast@gmail.com Distributed by: merkel.media Produced by: @jack_theproducer INTRO MUSIC Joel Thomas - Free The Rabbits YouTube | Apple Music | Spotify OUTRO MUSIC Joel Thomas - Imposter YouTube | Apple Music | Spotify
The simplicity of life back then is appealing today, as long as you don't mind Church hegemony, the occasional plague, trial by gossip — and the lack of ibuprofen. (Part two of a three-part series, “Cradle to Grave.”) SOURCES:Jordan Cavalier, performer at the New Jersey Renaissance Faire.Matt Schwarz, harpist at the New Jersey Renaissance Faire.Phillipp Schofield, professor of history at Aberystywth University.Neslihan Şenocak, professor of history at Columbia University. RESOURCES:A People's Church: Medieval Italy and Christianity, 1050–1300, co-edited by Agostino Paravicini Bagliani and Neslihan Şenocak (2023).The Routledge Handbook of Medieval Rural Life, edited by Miriam Müller with a contribution by Phillip Schofield (2021).Monty Python and the Holy Grail, film (1975). EXTRAS:"Are You Having a Midlife Crisis?" by No Stupid Questions (2022).
Talking points: myth, psychology, purposeI've loved myths and legends since I was a kid. As a man, that love has only grown because they can serve up powerful, meaningful guidance. So this week, we're digging into what Arthur, Excalibur, and the Holy Grail teach about the journey of the mature masculine.(00:00:00) - Intro(00:02:38) - Boyhood, coming of age, and crossing the thresholds of manhood(00:07:45) - The symbol and importance of Excalibur(00:16:04) - The sword in the stone CAN'T be pulled by might(00:18:33) - The meaning of pursuing the “holy grail”(00:22:36) - Purpose and ego don't usually mix
As our financial system is in the process of undergoing drastic changes, we may have to contend with something called the GENIUS Act. GENIUS is an acronym for Guiding and Establishing National Innovation for U.S. Stablecoin. It would be the digital and financial Holy Grail for the Surveillance State. However, President Trump is signaling a strong interest in gold; the idea of a gold-backed monetary shift is no longer just speculation—it may be part of the broader monetary realignment already in motion. It is a great alternative to stablecoin surveillance money. Tonight on Ground Zero with Clyde Lewis and financial analyst, Alan Johnson, starting at 7 pm, pacific time on groundzeroplus.com. Call in to the LIVE show: 503-225-0860 #groundzeroplus #ClydeLewis #gold #stablecoin