Podcasts about methodological

Cold OpenI just heard the duly-elected President of these United States... Donald J. Trump... brag about dropping the atom bomb. On Hiroshima.My god.Steven Colbert? Jon Stewart...?Once, these guys were subversive... were daring. But...But with troops still in the California streets and missiles in Mid-Eastern air...Haven't comedians become nauseatingly... tone dead?When the Comedy stops being funny…We're in deep shit. Especially anybody different. Like, say… autistics..[music theme]IntroYou're listening to Trigger Warnings, episode 2 … a new project of AutisticAF Out Loud podcast.I'm Johnny Profane. Your fiercely divergent guide to what's actually happening in the news.Gimme 10 minutes? I'll give you my neurodivergent world.Today: “Not Everything's Funny: Colbert, Trump .. & Hiroshima.” Military deployments in two cities, Constitutional challenges mounting, and one burning question: Are we witnessing democratic norms under assault in real time? And trying to just laugh it off?For an ever deeper dive, I've included footnotes and readings in the subStack.Content Note: civil unrest, military deployment, law enforcement actions, concerns about democratic institutions + experiences & opinions of one autistic voice... in my 70s.[music theme]ShowAct 1: The Unprecedented BreakI just heard the duly-elected President of these United States... Donald J. Trump... brag about dropping the atom bomb. On Hiroshima.[1]At a NATO summit.In front of the world.My god.Let me tell you what just happened. Because the News? They aren't "reporting" just how fucked up this really is.[music freedom, 8 bars]No President Has Ever Done ThisSince the guy who dropped those bombs in 1945…Harry Truman…stopped defending his decision…cuz he stopped being president in 1952.No American president since… has dared… brag about Hiroshima. Or Nagasaki.[2]Not one.You know why? Because even the worst of them understood something. Those bombs killed 200,000 people.[3] Mostly civilians. Women. Children. Grandparents.Even Eisenhower… the guy American history class sayswon World War II… Even he said the bombing "never ceased troubling me." He called it completely unnecessary.[4]Obama visited Hiroshima in 2016.[5] He didn't apologize. But he didn't brag either.Reagan talked about nuclear weapons. But he said "a nuclear war can never be won."[6]Every president since Truman understood this was serious shit. Sacred ground. You don't joke around about vaporizing cities.Not Trump.He's bragging. Comparing his conventional strikes to atomic bombs. Like it's a video game."We have the best nuclear technology," he said. "The best equipment in the world."Like… nuclear weapons were toys.[music]Trump Just Shattered “Normal”Yesterday at the NATO summit in The Hague, Trump compared his strikes on Iran to Hiroshima.His exact words: "I don't want to use an example of Hiroshima. I don't want to use the example of Nagasaki, that was essentially the same thing. That ended that war, this ended this war."[7]He was bragging. Bragging about nuclear destruction. Like a fucking business deal."That hit ended the war," he said. Chest puffed out. Proud as hell.This is what we've come to. The President casually referencing the incineration of 200,000 humans… as a model for current policy.At an international summit.On camera.With full makeup.[music 8 bars, freedom]You know social media… if you take a sec to hit subscribe, like, share? A lot more people will check it out. Just one click… and you do a lotta good.[music, freedom]The Comedy ProblemHow are we supposed to respond? Where's the outrage?In other words, where are the comedians? Most Gen Z-ers and younger get their news from late night comedy shows.[8]Colbert will try out a "new" joke tonight. Stewart will do his smirk. They'll treat this like another Trump gaffe they can mine for laughs.[9]But it's not funny anymore.Once, these guys were subversive... were daring. But...Haven't they become nauseatingly... tone dead?You can't satirize someone who's already become a parody of human decency. Someone the scriptures of all major religions would label simply… evil?Bragging about mass murder... what the fuck is left to mock?Comedy works when there's a shared understanding of normal. When people have shame. When some lines… you just don't cross.But Trump crossed the biggest. With a smile. Not one objection from a room full of reporters. Just brief sneers from a TV full of comedians.So, Canary-in-the-coal-mine time….When the Comedy stops being funny…We're in deep shit. Especially anyone different. Like, say… autistics…[music]Why This MattersThis isn't about politics. Left or right.This is about what kind of country we are.For 80 years, American presidents understood that Hiroshima was different. Special. Unspeakable.[10]They might defend it…quickly, quietly. Say, “It saved lives.” Then quickly, move on.They understood Power comes with burdens… responsibility, accountability, humanity. That killing 200,000 people isn't something you do a victory spike over.Trump doesn't understand that weight.Or worse... he doesn't care.Ya, know, worse yet? Maybe he does care. About the bullying power that his brutish remarks burn into the world's memory.[music]Act 2: When Institutions FailWith troops still in the California streets, missiles in Mid-Eastern skies… and a Bully-in-Chief in the pulpit…Comedy… and art… fall silent.Corporate News? Well it talks… too much. But it just isn't saying anything. They don't cover reality anymore. They've been cowed into repeating Administration lies… through shell-shocked faces.When the President of the United States casually references nuclear genocide... and we fear he might just use them sometime …within the next two weeks…like all of his jokes…that become threats…that become promises kept to his base…Our cultural tools break down.We don't have frameworks for this.We have jokes for corrupt politicians. For liars. For cheaters. That subversive humor can shed a light into Democratic or Republican darkness. Through a shared giggle.But jokes about dropping nukes?They're just distractions. Like… witty comebacks, really killer memes, and the occasional truly thoughtful opinion piece in the New York Times.[music]What We're Really FacingThis is what authoritarianism starts like.[11] Not jackboots and death squads.Just a man who thinks mass murder… is something to celebrate. A man who doesn't understand why some folks might find that disturbing.The scariest part? He said this at NATO. To our allies.Heard round the world. By any country that remembers World War II. What nuclear weapons actually do.Like say, Japan.[music]Are the Democrats' the Alternative?The political opposition? They're not exactly rising to the moment. What the fuck are Democrats doing?[12]Running the same playbook they've used since Hillary lost."We're the adults in the room.""At least we're not Trump. Vote for us because we're not insane.""You just wait for the midterms… oh, boy. We really got him now."We need more than just "At least, we're not that guy."You need to explain why this is fucking terrifying.Wait… Forget all that.Say as little as absolutely necessary.Just fucking act already.[music]Where We Are NowSo here we are. And we're all supposed to pretend this is normal.It's not normal.It's not funny.And it's not sustainable. Maybe not survivable.[music]The TruthTrump just told the world that he thinks nuclear destruction is a deal-making path… worth aspiring to. :Proudly.That's not politics. That's not even partisanship.That's a fundamental break with human decency.And if we can't say that out loud... if we can't admit how fucked up this is...We're already lost.[music AutisticAF Out Loud theme]OutroThis has been Trigger Warnings: Fiercely Divergent News. Reminding you we navigate a world that wasn't built for us Neurodivergents… and it may be time… to build our own.Another warning sign that, ya know… human decency? All bets are off.Which doesn't bode well for anybody who is different.Next week? 10 more minutes of my neurodivergent world. Until then, take care of your beautiful pattern-seeking, divergent brain.And… stay safe? Stay fierce.#AutisticAF Out Loud Newsletter is a reader-supported publication. Click o receive new posts… free. To support my work, consider becoming a paid subscriber.Binge on the most authentic autistic voice in podcasting.7 decades of raw truth, real insights, zero yadayada.Footnotes[1] https://www.aljazeera.com/video/newsfeed/2025/6/25/trump-compares-iran-strikes-to-hiroshima-and-nagasakihttps://www.huffpost.com/entry/trump-hiroshima-nagasaki-iran_n_685bf52ee4b024434f988a73https://www.middleeasteye.net/news/hit-ended-war-trump-likens-iran-strikes-hiroshima-bombinghttps://cbs4local.com/news/nation-world/president-donald-trump-compares-iran-strikes-to-hiroshima-bombing-nagasaki-claims-successful-end-to-conflict-nato-summit-netherlands-secretary-general-mark-rutte-operation-midnight-hammer[2]: While President Truman initially called the atomic bomb "the greatest thing in history" aboard his ship returning from Potsdam, his public statements were more measured, describing it as "a harnessing of the basic power of the universe".https://millercenter.org/the-presidency/presidential-speeches/august-6-1945-statement-president-announcing-use-bombTruman defended the decision but stopped discussing it publicly after leaving office. No subsequent president has publicly celebrated or bragged about the atomic bombings until Trump's 2025 remarks.https://www.nps.gov/articles/trumanatomicbomb.htm[3]: Death toll estimates for the atomic bombings vary significantly. The Manhattan Engineer District initially estimated 105,000 total deaths (66,000 in Hiroshima, 39,000 in Nagasaki) by end of 1945. The International Campaign to Abolish Nuclear Weapons estimates 140,000 in Hiroshima and 74,000 in Nagasaki by end of 1945. Methodological challenges include destroyed records, uncertain pre-bombing populations, and radiation-related deaths over time.https://www.atomicarchive.com/resources/documents/med/med_chp10.html[4]: Eisenhower expressed his "grave misgivings" about the atomic bombing in his memoir, stating he believed "Japan was already defeated and that dropping the bomb was completely unnecessary." He also noted his concern that the U.S. "should avoid shocking world opinion by the use of a weapon whose employment was, I thought, no longer mandatory as a measure to save American lives."https://www.aei.org/op-eds/japan-was-already-defeated-the-case-against-the-nuclear-bomb-and-for-basic-morality/Critics note this was a post-war reflection written nearly two decades later, not a contemporaneous military assessment.[5]: Obama visited Hiroshima in May 2016, becoming the first sitting U.S. president to do so. He spoke of the "silent cry" of victims and called for nuclear disarmament while carefully avoiding any apology, stating: "We stand here in the middle of this city and force ourselves to imagine the moment the bomb fell... we listen to a silent cry".https://abc3340.com/news/nation-world/obama-at-hiroshima-death-fell-from-the-sky-05-27-2016-103848173[6]: Reagan's famous statement "A nuclear war cannot be won and must never be fought" was delivered in his 1984 State of the Union address, reflecting his commitment to nuclear deterrence while pursuing arms reduction with the Soviet Union.[7]: Trump's exact words at the NATO summit on June 25, 2025: "I don't want to use an example of Hiroshima. I don't want to use an example of Nagasaki, but that was essentially the same thing that ended that war, this ended this war"[4].https://www.middleeasteye.net/news/hit-ended-war-trump-likens-iran-strikes-hiroshima-bombinghttps://cbs4local.com/news/nation-world/president-donald-trump-compares-iran-strikes-to-hiroshima-bombing-nagasaki-claims-successful-end-to-conflict-nato-summit-netherlands-secretary-general-mark-rutte-operation-midnight-hammerThis represents the first time a U.S. president has compared current military actions to the atomic bombings in a celebratory manner.[8]: Research indicates late-night political comedy shows serve as significant news sources, particularly for younger demographics. "The Late Show with Stephen Colbert" averaged 8.7% viewership share in 2024, reaching approximately 281,000 viewers in the 18-49 demographic nightly[15][16].https://screenrant.com/stephen-colbert-ratings-late-show-2024-explained/https://screenrant.com/stephen-colbert-ratings-late-show-2024-explained/ Studies suggest these programs have the most impact on politically inattentive audiences who learn about politics inadvertently through satirical content.[9]: Following Trump's Iran strikes, Colbert addressed the actions through his typical comedic framework, with segments like "Trump's Weird Iran War Speech" and jokes about intelligence reports contradicting Trump's claims of "obliteration." Colbert quipped "Oops-a-nuke-y" regarding reports that Iran's nuclear capabilities remained largely intact.https://www.tvinsider.com/1199026/stephen-colbert-trump-f-bomb-rant-monologue-video/[10]: The concept of a "nuclear taboo"—an international norm against the use of nuclear weapons—has been maintained since 1945. Political scientist Nina Tannenwald defines this as "a de facto prohibition against the first use of nuclear weapons" that creates a shared understanding of the illegitimacy and immorality of nuclear weapons use[18].https://en.wikipedia.org/wiki/Nuclear_tabooTrump's comparison breaks this longstanding presidential restraint.[11]: Harvard political scientists Steven Levitsky and Daniel Ziblatt identify four markers of authoritarian risk: rejecting democratic rules, denying opponent legitimacy, tolerating violence, and curtailing civil liberties. They argue Trump is the first U.S. politician since the Civil War to meet all four criteria19.https://www.newsweek.com/harvard-political-science-professor-donald-trump-authoritarian-how-democracy-778425Constitutional scholar Elaine Scarry argues nuclear weapons create "thermonuclear monarchy" by concentrating unprecedented destructive power in executive hands, fundamentally undermining democratic governance.https://www.barnesandnoble.com/w/thermonuclear-monarchy-elaine-scarry/1111087819https://futureoflife.org/wp-content/uploads/2016/04/Elaine_Scarry_MIT_April2.pdf[12]: Democratic responses to Trump's Iran strikes showed internal divisions. House No. 2 Democrat Katherine Clark called the strikes "unauthorized & unconstitutional," while Senator Chris van Hollen argued they violated congressional war powers. However, critics note Democratic presidents have similarly bypassed Congress for military actions, weakening their constitutional arguments[22][23].https://www.msnbc.com/opinion/msnbc-opinion/us-bombs-iran-attacks-trump-constitution-rcna214580https://www.cnn.com/2025/06/23/politics/trump-iran-legal-constitutional-article-1-article-2 This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit johnnyprofaneknapp.substack.com/subscribe

Today, hosts Robert J. Marks and Angus Menuge welcome Dr. Robert Larmer to discuss methodological naturalism, the topic of his chapter in Minding the Brain, a recent anthology exploring the mind-body debate. Methodological naturalism is the view that science should only appeal to natural causes and never to supernatural or non-physical causes, even if they exist. Dr. Larmer argues that methodological Read More › Source

Support us on Patreon!Thanks to Skratch Labs for sponsoring the podcast! Get a free sample pack on us!This week on Your Diet Sucks, we're digging into one of the most misunderstood—and over-marketed—topics in endurance sports: nutrition for female athletes.You've probably heard the myths: women should eat for their body type, avoid carbs during their cycle, or that we're not just small men when it comes to fueling. But most of that advice isn't based on solid science; it's based on outdated research, rigid stereotypes, and a whole lot of pseudoscience.In this episode, Kylee and Zoë unpack:​Why most sports science has ignored female athletes for decades​How hormonal fluctuations, birth control, and life stage transitions affect fueling​What's actually different about female endurance physiology​The truth about somatotypes (ectomorph, mesomorph, endomorph) and why they're BS​Evidence-backed nutrition strategies for training, recovery, and long-term health​Why research gaps are still being filled by grifters, and how to stay skepticalWhether you're menstruating, on birth control, pregnant, postpartum, or in perimenopause—or you coach or care about someone who is—this episode is your myth-busting guide to what women really need to fuel their performance.Thanks to Janji for supporting the podcast! Use code YDS for 10% off your purchase. REFERENCESCowley, E. S., Olenick, A. A., McNulty, K. L., & Ross, E. Z. (2021).“Invisible sportswomen”: The sex data gap in sport and exercise science research. Women in Sport and Physical Activity Journal, 29(2), 146–151. https://doi.org/10.1123/wspaj.2020-0051Elliott-Sale, K. J., Minahan, C. L., de Jonge, X. A. K. J., Ackerman, K. E., Sipilä, S., Constantini, N. W., Lebrun, C. M., Hackney, A. C., & Nindl, B. C. (2021).Methodological considerations for studies in sport and exercise science with women as participants: A working guide for standards of practice for research on women. Sports Medicine, 51(5), 843–861. https://doi.org/10.1007/s40279-021-01435-2International Society of Sports Nutrition (Sims, S. T., Kerksick, C. M., Smith-Ryan, A. E., de Jonge, X. A. K. J., Hirsch, K. R., Arent, S. M., & Antonio, J.). (2023).International Society of Sports Nutrition Position Stand: Nutritional concerns of the female athlete. Journal of the International Society of Sports Nutrition, 20(1), 15. https://doi.org/10.1186/s12970-023-00541-wMountjoy, M., Sundgot-Borgen, J., Burke, L., Ackerman, K. E., Blauwet, C., Constantini, N., Lebrun, C., Lundy, B., Melin, A., Meyer, N., Sherman, R., Tenforde, A., Torstveit, M. K., & Budgett, R. (2018).IOC consensus statement: Relative Energy Deficiency in Sport (RED-S). British Journal of Sports Medicine, 52(11), 687–697. https://doi.org/10.1136/bjsports-2018-099193Sims, S. T. (2016).ROAR: How to match your food and fitness to your unique female physiology for optimum performance, great health, and a strong, lean body for life. Rodale Books.

Identifying and Evaluating Young Children with Developmental Central Hypotonia: An Overview of Systematic Reviews and ToolsChildren with developmental central hypotonia have reduced muscle tone secondary to non-progressive damage to the brain or brainstem. Children may have transient delays, mild or global functional impairments, and the lack of a clear understanding of this diagnosis makes evaluating appropriate interventions challenging. This overview aimed to systematically describe the best available evidence for tools to identify and evaluate children with developmental central hypotonia aged 2 months to 6 years. A systematic review of systematic reviews or syntheses was conducted with electronic searches in PubMed, Medline, CINAHL, Scopus, Cochrane Database of Systematic Reviews, Google Scholar, and PEDro and supplemented with hand-searching. Methodological quality and risk-of-bias were evaluated, and included reviews and tools were compared and contrasted. Three systematic reviews, an evidence-based clinical assessment algorithm, three measurement protocols, and two additional measurement tools were identified. For children aged 2 months to 2 years, the Hammersmith Infant Neurological Examination has the strongest measurement properties and contains a subset of items that may be useful for quantifying the severity of hypotonia. For children aged 2-6 years, a clinical algorithm and individual tools provide guidance. Further research is required to develop and validate all evaluative tools for children with developmental central hypotonia.

Pinterest vs. Google: The Visual Search Revolution This episode, sponsored by the A&M Consumer and Retail Group, Simbe, Mirakl, Ocampo Capital, Infios, and ClearDemand, explores how Pinterest is disrupting traditional search engines and transforming product discovery through visual search. Our retail experts analyze surprising data and debate what it means for brands' marketing strategies. Key Moments: 0:03 - Breaking news: Adobe research reveals Pinterest emerging as a search engine competitor 0:14 - Surprising statistic: 39% of US consumers have used Pinterest as a search engine 0:23 - Gen Z leading the trend at 47%, with decreasing adoption across older generations 0:36 - Eye-opening claim: 36% of respondents start searches on Pinterest instead of Google 0:48 - Perception advantage: 60% say Pinterest results feel more tailored than Google results 1:10 - Anne Mezzenga discusses how this trend connects to Meta's recent search announcements with ChatGPT 1:34 - Critical insight: Image-based search is driving this shift, especially among younger demographics 1:47 - Industry validation: Google's own data shows 20% of image searches are commerce-related 2:02 - Real-world confirmation: Designers and stylists exclusively using Pinterest for professional searches 2:25 - Historical context: How search is evolving from text-based to visual discovery 3:19 - Ben Millers confirms search fragmentation is a major retail trend affecting marketing investments 4:05 - Research critique: Ben challenges Adobe's methodology and questions the "36%" headline claim 4:46 - Methodological issues: Survey of just 800 people on a single day with unclear geographic representation 5:14 - Distinction between general search and commerce intent: "I'm not going to Pinterest to find out who was president in 1962" 6:28 - The commerce challenge: Getting searches to convert to purchases remains a critical hurdle 7:37 - Anne clarifies: Pinterest's value is specifically for purchase intent and product discovery 8:03 - Integration point: Pinterest results appearing in ChatGPT, Perplexity, and Gemini searches 8:47 - Market reality check: Google still dominates overall search, but commerce search is fragmenting 9:35 - Future marketing challenge: How to influence search when traditional paid placements aren't available 10:19 - Opportunity assessment: Commerce search is currently "fair game" for platforms to redefine The episode highlights how visual search is fundamentally changing product discovery and creating new opportunities for retailers who understand these emerging consumer behaviors. Catch the full episode here: https://youtu.be/BrQ0kfPY4LA #pinterest #visualsearch #ai #google #retailtech #retailnews #retailstrategy ##retailtrends

Defenders: Excursus on Creation of Life and Biological Diversity (Part 29): Methodological Naturalism

Are you unknowingly missing key nutrients in your diet? Dr Carlene Starck joins us to break down her Priority Nutrients research, revealing the vitamins and minerals Australians and New Zealanders are lacking. From energy to immune health, these hidden micronutrient inadequacies could be holding you back. Tune in to find out what your diet might be missing—and how to fix it!We cover: 3:00 Why this research was undertaken 6.00 Common nutrient inadequacies in Aus/NZ 8.00 Protein intake target - should it be higher? 9:45 Are the Nutrient Reference Values (NRVs) outdated? 11:45 Nutrients that have Suggested Dietary Targets (SDTs) 13:15 Methodological approach of the research 29:10 Key findings from the research31:30 Vitamin D deficiency in Aus/NZ32:30 Calcium targets, absorption and what do we know to be true about calcium and bone health and calcium and fractures. 39:20 Calcium bioavailability - how is this researched? 41:00 How to get vitamin D from food?45:00 How and when to get your vitamin D status assessed 47:30 Omega-3 intake 50:00 Interesting omega-3 findings 51:30 Adult men - the forgotten group? 53:10 Teenagers - 15 inadequate nutrients! 54:00 Findings in females 19-45 years 56:20 How to know if you are not getting enough of certain vitamins and minerals?60:00 How does exercise impact vitamin and mineral needs?62:45 How can someone maintain healthy eating habits while still enjoying what they eat? 65:45 How can your research findings be used in the real world? One-liners you don't want to miss:“We know that calcium intake is low, what we didn't know was just how low and how severe that inadequacy was.” “It looks like higher intakes of vitamin C are really beneficial of 150-200mg/day. It doesn't sound very much when you can go and buy vitamin C tablets which are 1000mg/day but the key with that is our body can't absorb all of that at one time.”“People are only over-consuming in nutrients of concern.”“How we live, where we live, our lifestyles, our overall diet composition, how much exercise we are doing; all of these things really effect magnesium intake.” “Your body is not going to run out of calcium in terms of your blood levels. But what happens is when you don't have enough calcium in your blood it will start to leach out of your bones.” “Vitamin D intake will help to decrease fracture risk. We need sufficient vitamin D to make sure we can adequately absorb calcium.” “Iron, vitamin D, calcium and the omega-3s, if you are exercising and very active. If you are concerned about priority nutrients those are the four. The other one that is also highlighted is selenium, that's because it has antioxidant function. Selenium and vitamin E also work together, so getting both of these in.”ReferenceStarck CS, Cassettari T, Beckett E, Marshall S, Fayet-Moore F. Priority nutrients to address malnutrition and diet-related diseases in Australia and New Zealand. Front Nutr. 2024 Mar 13;11:1370550. doi: 10.3389/fnut.2024.1370550. PMID: 38544756; PMCID: PMC10966131.Support the show

If task-switching under stress wrecks your day, you're not alone. Researchers have spent 20+ years studying executive functioning in ADHD, and honestly? Their findings are a bit of a mess.In this episode, we break down a new critical review of the research (and trust me, the we have some thoughts). We're talking hot executive functioning, emotional overload, and why decision-making goes out the window under stress.What you'll learn:Why your brain freezes in high-pressure situations (and what science says you can do about it)The real reason ADHD professionals struggle with task transitions and emotional reactivityWhat this research tells us about why we cry over emails (yes, really)Practical, science-backed tools to reset your brain after an emotional overloadThere's a reason ADHD professionals burn out faster—and it has everything to do with how we process stress. Let's break it down.References:A critical review of hot executive functioning in youth attention-deficit/hyperactivity disorder: Methodological limitations, conceptual considerations, and future directionsP.S. Skye here! Whenever you're ready to grow your business without ADHD overwhelm, here's how I can help: Get ADHD-friendly business strategies in your inbox No boring productivity hacks—just simple, research-backed tips to help you stay on track, stop overthinking, and get things done. All in quick, easy-to-read emails. Click here to join the community. Find out what's holding you back. Stuck in procrastination, burnout, or endless to-do lists? My 48-hour Business Audit will pinpoint what's slowing you down and give you a simple plan to fix it. Click here to grab one before they go. Join my Focused Balanced Growth Program Tired of systems that don't work for your brain? Get ADHD-friendly tools to stay focused, consistent, and grow your business without burnout. DM me on Instagram with “UNLOCK” to learn more. Work with me One-on-One Running a 6-7 figure business but struggling with focus, decisions, or scaling? Let's create a plan that works for your brain. Limited spots available— DM me on Instagra...

Summary In this post, we explore different ways of understanding and measuring malevolence and explain why individuals with concerning levels of malevolence are common enough, and likely enough to become and remain powerful, that we expect them to influence the trajectory of the long-term future, including by increasing both x-risks and s-risks. For the purposes of this piece, we define malevolence as a tendency to disvalue (or to fail to value) others' well-being (more). Such a tendency is concerning, especially when exhibited by powerful actors, because of its correlation with malevolent behaviors (i.e., behaviors that harm or fail to protect others' well-being). But reducing the long-term societal risks posed by individuals with high levels of malevolence is not straightforward. Individuals with high levels of malevolent traits can be difficult to recognize. Some people do not take into account the fact that malevolence exists on a continuum, or do not [...] ---Outline:(00:07) Summary(04:17) Malevolent actors will make the long-term future worse if they significantly influence TAI development(05:32) Important caveats when thinking about malevolence(05:37) Dark traits exist on a continuum(07:31) Dark traits are often hard to identify(08:54) People with high levels of dark traits may not recognize them or may try to conceal them(12:17) Dark traits are compatible with genuine moral convictions(13:22) Malevolence and effective altruism(15:22) Demonizing people with elevated malevolent traits is counterproductive(20:16) Defining malevolence(21:03) Defining and measuring specific malevolent traits(21:34) The dark tetrad(25:03) Other forms of malevolence(25:07) Retributivism, vengefulness, and other suffering-conducive tendencies(26:56) Spitefulness(28:15) The Dark Factor (D)(29:29) Methodological problems associated with measuring dark traits(30:39) Social desirability and self-deception(31:14) How common are malevolent humans (in positions of power)?(33:02) Things may be very different outside of (Western) democracies(33:31) Prevalence data for psychopathy and narcissistic personality disorder(34:20) Psychopathy prevalence(36:25) Narcissistic personality disorder prevalence(40:38) The distribution of the dark factor + selected findings from thousands of responses to malevolence-related survey items(42:13) Sadistic preferences: over 16% of people agree or strongly agree that they “would like to make some people suffer even if it meant that I would go to hell with them”(43:42) Agreement with statements that reflect callousness: Over 10% of people disagree or strongly disagree that hurting others would make them very uncomfortable(44:45) Endorsement of Machiavellian tactics: Almost 15% of people report a Machiavellian approach to using information against people(45:20) Agreement with spiteful statements: Over 20% of people agree or strongly agree that they would take a punch to ensure someone they don't like receives two punches(45:57) A substantial minority report that they “take revenge” in response to a “serious wrong”(46:44) The distribution of Dark Factor scores among 2M+ people(49:17) Reasons to think that malevolence could correlate with attaining and retaining positions of power(49:47) The role of environmental factors(52:33) Motivation to attain power(54:14) Ability to attain power(59:39) Retention of power(01:01:02) Potential research questions and how to help(01:17:48) Other relevant research agendas(01:18:33) Author contributions(01:19:26) Acknowledgments

I denne episoden snakker vi med Marcus Småvik Dasa, fysioterapeut og ansatt ved Olympiatoppen Vest. Marcus leverte nylig sin doktorgrad på tematikken "lav energitilgjengelighet" i idrett (REDs). Hva handler dette begrepet om og hvem gjelder det? Kontaktinfo X Researchgate Referanser Energetics, energy availability and Relative Energy Deficiency in Sport (REDs) in female football players - Methodological perspectives and research implications

Lecture summary: The United Nations Charter order (UNCO) and the co-evolved liberal international order (LIO) are contested with a heretofore unknown force. The steep rise in contestations in the realm of public politics rather than the courtroom demonstrates a shift from normal contestation as a source of legitimacy and ordering towards deep contestation as a political challenge of foundational elements of liberal order. Today, not only in the Global South but also across Europe and North America, sceptics of globalization on the political left and nationalist-populists on the political right are challenging the fundamental pillars of the LIO (i.e., democracy, economic openness, and multilateralism). The process is paired by growing contestations of international law that is codified in the UN Charter including contestation of core norms of the UNCO (i.e., non-intervention, human rights, and sovereignty). While the effect of deep contestation is unknowable, we do know however that normal contestation is the essence of everyday politics. The clash of interests, norms, and ideas is entirely normal. Yet, contestation can also be degenerative, moving political outcomes away from desired ends through ad hoc and perhaps inconsistent compromises. As core norms of the LIO and UNCO have become deeply contested, we require a better understanding about the expected effects. Access to contestation as the right to speak and participate in political decisions is a necessary condition for normative legitimacy and mutual recognition of the norms that govern us. Achieving this condition involves struggles about norm(ative) meaning-in-use which take place on distinct sites of global order. This raises a question about time, substance, and norm(ative) change in global order more generally and, more specifically, which elements of international order ought to be retained. The lecture posits that the observed qualitative shift from constitutive everyday contestations towards potentially degenerative political contestation calls for a methodological stocktake of how contestations work with regard to global re/ordering, i.e. whose practices count and whose norms ought to count in that process? Professor Antje Wiener FAcSS, MAE, holds the Chair of Political Science, especially Global Governance at the University of Hamburg where she is a member of the Faculty of Business and Social Sciences as well as the Law Faculty. She is an elected By-Fellow of Hughes Hall University of Cambridge, a Fellow of the UK’s Academy of Social Sciences, and a Member of the Academia Europea. Her research and teaching centres on International Relations theory, especially norms research and contestation theory. Previously she held Chairs in International Studies at Queen’s University Belfast and the University of Bath and taught at the Universities of Stanford, Carleton, Sussex and Hannover. Current research projects include ‘Contested Climate Justice in Sensitive Regions’ at the Cluster of Excellence Climate, Climatic Change and Society (CLICCS) as well as ‘Doing Theory – From Where and What For? A Backpackers’ Guide to Knowledge Production’ at the Centre for Sustainable Society Research (CSS) among others. With James Tully, she is co-founding editor of Global Constitutionalism (CUP, since 2012 ). And she also edits the Norm Research in International Relations Series (Springer). She serves on several Committees of the Academy of Social Sciences . In 2021, she concluded her second three-year term as elected member of the Executive Committee of the German Political Science Association (DVPW). Her book ‘Contestation and Constitution of Norms in Global International Relations’ (CUP 2018) was awarded the International Law Section’s Book Prize in 2020. And her most recent book ‘Contesting the World: Norm Research in Theory and Practice’ co-edited with Phil Orchard was published with CUP in 2024.

Lecture summary: The United Nations Charter order (UNCO) and the co-evolved liberal international order (LIO) are contested with a heretofore unknown force. The steep rise in contestations in the realm of public politics rather than the courtroom demonstrates a shift from normal contestation as a source of legitimacy and ordering towards deep contestation as a political challenge of foundational elements of liberal order. Today, not only in the Global South but also across Europe and North America, sceptics of globalization on the political left and nationalist-populists on the political right are challenging the fundamental pillars of the LIO (i.e., democracy, economic openness, and multilateralism). The process is paired by growing contestations of international law that is codified in the UN Charter including contestation of core norms of the UNCO (i.e., non-intervention, human rights, and sovereignty). While the effect of deep contestation is unknowable, we do know however that normal contestation is the essence of everyday politics. The clash of interests, norms, and ideas is entirely normal. Yet, contestation can also be degenerative, moving political outcomes away from desired ends through ad hoc and perhaps inconsistent compromises. As core norms of the LIO and UNCO have become deeply contested, we require a better understanding about the expected effects. Access to contestation as the right to speak and participate in political decisions is a necessary condition for normative legitimacy and mutual recognition of the norms that govern us. Achieving this condition involves struggles about norm(ative) meaning-in-use which take place on distinct sites of global order. This raises a question about time, substance, and norm(ative) change in global order more generally and, more specifically, which elements of international order ought to be retained. The lecture posits that the observed qualitative shift from constitutive everyday contestations towards potentially degenerative political contestation calls for a methodological stocktake of how contestations work with regard to global re/ordering, i.e. whose practices count and whose norms ought to count in that process?Professor Antje Wiener FAcSS, MAE, holds the Chair of Political Science, especially Global Governance at the University of Hamburg where she is a member of the Faculty of Business and Social Sciences as well as the Law Faculty. She is an elected By-Fellow of Hughes Hall University of Cambridge, a Fellow of the UK's Academy of Social Sciences, and a Member of the Academia Europea. Her research and teaching centres on International Relations theory, especially norms research and contestation theory. Previously she held Chairs in International Studies at Queen's University Belfast and the University of Bath and taught at the Universities of Stanford, Carleton, Sussex and Hannover. Current research projects include ‘Contested Climate Justice in Sensitive Regions' at the Cluster of Excellence Climate, Climatic Change and Society (CLICCS) as well as ‘Doing Theory – From Where and What For? A Backpackers' Guide to Knowledge Production' at the Centre for Sustainable Society Research (CSS) among others. With James Tully, she is co-founding editor of Global Constitutionalism (CUP, since 2012 ). And she also edits the Norm Research in International Relations Series (Springer). She serves on several Committees of the Academy of Social Sciences . In 2021, she concluded her second three-year term as elected member of the Executive Committee of the German Political Science Association (DVPW). Her book ‘Contestation and Constitution of Norms in Global International Relations' (CUP 2018) was awarded the International Law Section's Book Prize in 2020. And her most recent book ‘Contesting the World: Norm Research in Theory and Practice' co-edited with Phil Orchard was published with CUP in 2024.

Lecture summary: The United Nations Charter order (UNCO) and the co-evolved liberal international order (LIO) are contested with a heretofore unknown force. The steep rise in contestations in the realm of public politics rather than the courtroom demonstrates a shift from normal contestation as a source of legitimacy and ordering towards deep contestation as a political challenge of foundational elements of liberal order. Today, not only in the Global South but also across Europe and North America, sceptics of globalization on the political left and nationalist-populists on the political right are challenging the fundamental pillars of the LIO (i.e., democracy, economic openness, and multilateralism). The process is paired by growing contestations of international law that is codified in the UN Charter including contestation of core norms of the UNCO (i.e., non-intervention, human rights, and sovereignty). While the effect of deep contestation is unknowable, we do know however that normal contestation is the essence of everyday politics. The clash of interests, norms, and ideas is entirely normal. Yet, contestation can also be degenerative, moving political outcomes away from desired ends through ad hoc and perhaps inconsistent compromises. As core norms of the LIO and UNCO have become deeply contested, we require a better understanding about the expected effects. Access to contestation as the right to speak and participate in political decisions is a necessary condition for normative legitimacy and mutual recognition of the norms that govern us. Achieving this condition involves struggles about norm(ative) meaning-in-use which take place on distinct sites of global order. This raises a question about time, substance, and norm(ative) change in global order more generally and, more specifically, which elements of international order ought to be retained. The lecture posits that the observed qualitative shift from constitutive everyday contestations towards potentially degenerative political contestation calls for a methodological stocktake of how contestations work with regard to global re/ordering, i.e. whose practices count and whose norms ought to count in that process?Professor Antje Wiener FAcSS, MAE, holds the Chair of Political Science, especially Global Governance at the University of Hamburg where she is a member of the Faculty of Business and Social Sciences as well as the Law Faculty. She is an elected By-Fellow of Hughes Hall University of Cambridge, a Fellow of the UK's Academy of Social Sciences, and a Member of the Academia Europea. Her research and teaching centres on International Relations theory, especially norms research and contestation theory. Previously she held Chairs in International Studies at Queen's University Belfast and the University of Bath and taught at the Universities of Stanford, Carleton, Sussex and Hannover. Current research projects include ‘Contested Climate Justice in Sensitive Regions' at the Cluster of Excellence Climate, Climatic Change and Society (CLICCS) as well as ‘Doing Theory – From Where and What For? A Backpackers' Guide to Knowledge Production' at the Centre for Sustainable Society Research (CSS) among others. With James Tully, she is co-founding editor of Global Constitutionalism (CUP, since 2012 ). And she also edits the Norm Research in International Relations Series (Springer). She serves on several Committees of the Academy of Social Sciences . In 2021, she concluded her second three-year term as elected member of the Executive Committee of the German Political Science Association (DVPW). Her book ‘Contestation and Constitution of Norms in Global International Relations' (CUP 2018) was awarded the International Law Section's Book Prize in 2020. And her most recent book ‘Contesting the World: Norm Research in Theory and Practice' co-edited with Phil Orchard was published with CUP in 2024.

Lecture summary: The United Nations Charter order (UNCO) and the co-evolved liberal international order (LIO) are contested with a heretofore unknown force. The steep rise in contestations in the realm of public politics rather than the courtroom demonstrates a shift from normal contestation as a source of legitimacy and ordering towards deep contestation as a political challenge of foundational elements of liberal order. Today, not only in the Global South but also across Europe and North America, sceptics of globalization on the political left and nationalist-populists on the political right are challenging the fundamental pillars of the LIO (i.e., democracy, economic openness, and multilateralism). The process is paired by growing contestations of international law that is codified in the UN Charter including contestation of core norms of the UNCO (i.e., non-intervention, human rights, and sovereignty). While the effect of deep contestation is unknowable, we do know however that normal contestation is the essence of everyday politics. The clash of interests, norms, and ideas is entirely normal. Yet, contestation can also be degenerative, moving political outcomes away from desired ends through ad hoc and perhaps inconsistent compromises. As core norms of the LIO and UNCO have become deeply contested, we require a better understanding about the expected effects. Access to contestation as the right to speak and participate in political decisions is a necessary condition for normative legitimacy and mutual recognition of the norms that govern us. Achieving this condition involves struggles about norm(ative) meaning-in-use which take place on distinct sites of global order. This raises a question about time, substance, and norm(ative) change in global order more generally and, more specifically, which elements of international order ought to be retained. The lecture posits that the observed qualitative shift from constitutive everyday contestations towards potentially degenerative political contestation calls for a methodological stocktake of how contestations work with regard to global re/ordering, i.e. whose practices count and whose norms ought to count in that process?Professor Antje Wiener FAcSS, MAE, holds the Chair of Political Science, especially Global Governance at the University of Hamburg where she is a member of the Faculty of Business and Social Sciences as well as the Law Faculty. She is an elected By-Fellow of Hughes Hall University of Cambridge, a Fellow of the UK's Academy of Social Sciences, and a Member of the Academia Europea. Her research and teaching centres on International Relations theory, especially norms research and contestation theory. Previously she held Chairs in International Studies at Queen's University Belfast and the University of Bath and taught at the Universities of Stanford, Carleton, Sussex and Hannover. Current research projects include ‘Contested Climate Justice in Sensitive Regions' at the Cluster of Excellence Climate, Climatic Change and Society (CLICCS) as well as ‘Doing Theory – From Where and What For? A Backpackers' Guide to Knowledge Production' at the Centre for Sustainable Society Research (CSS) among others. With James Tully, she is co-founding editor of Global Constitutionalism (CUP, since 2012 ). And she also edits the Norm Research in International Relations Series (Springer). She serves on several Committees of the Academy of Social Sciences . In 2021, she concluded her second three-year term as elected member of the Executive Committee of the German Political Science Association (DVPW). Her book ‘Contestation and Constitution of Norms in Global International Relations' (CUP 2018) was awarded the International Law Section's Book Prize in 2020. And her most recent book ‘Contesting the World: Norm Research in Theory and Practice' co-edited with Phil Orchard was published with CUP in 2024.

Here's the original video from where this audio came. Here's a list of links to John reading every chapter (released so far) in his 2021 book Contending Perspectives. I have edited both the video and audio to eliminate mistakes, coughs, interruptions, and etc. Sections in this chapter 1:58 - Methodological individualism, praxeology, and subjectivism 9:46 - Market process 12:24 - Austrian business cycle theory 16:27 - Method 17:28 - Views of human nature and justice 18:35 - Standards 20:46 - Contemporary activities 21:48 - Criticisms 23:51 - Final rejoinder 25:15 - Further reading

Here's the from where this audio came. Here's a list of links to (released so far) in his 2021 book Contending Perspectives. I have edited both the video and audio to eliminate mistakes, coughs, interruptions, and etc. Sections in this chapter 1:58 - Methodological individualism, praxeology, and subjectivism 9:46 - Market process 12:24 - Austrian business cycle theory 16:27 - Method 17:28 - Views of human nature and justice 18:35 - Standards 20:46 - Contemporary activities 21:48 - Criticisms 23:51 - Final rejoinder 25:15 - Further reading

Dawn Jones' and team's research unexpectedly unveiled the use of scrapbooks as a new methodological approach to action research within practice as well as research studies. Dawn proposes that scrapbooks could provide a rich collection of documented evidence to support both the inspection framework and the EYFS outcomes.   Read Dawn's article here: https://thevoiceofearlychildhood.com/scrapbooks-as-a-methodological-and-practice-based-tool/   Listen to more: If you enjoyed this episode, you might also like to take a listen to and read Dawn's previous episodes and articles:   What do children have to say about their environment? -      https://thevoiceofearlychildhood.com/what-do-children-have-to-say-about-their-environment/   Problematising behaviour management systems -      https://thevoiceofearlychildhood.com/problematising-behaviour-management-systems/   Episode break down: 00:00 – Research context 09:00 – Scrapbooks as a listening tool 11:00 – Slowing down as a researcher and educator 14:00 – A collaborative tool for practice 21:00 – Empowering students to make an impact 25:00 – Scrapbooks as an analytical tool 30:00 – Scrapbooks for aiding inspection processes 32:30 – Collaborative tool and aiding joint observations 35:00 – Developmentally appropriate documentation 40:00 – Not having complete control as educator 44:00 – Slowing down, pondering and wallowing 46:30 – Accessibility of research   For more episodes and articles visit The Voice of Early Childhood website: https://www.thevoiceofearlychildhood.com

In this episode of RAPM Focus, Editor-in-Chief Brian Sites, MD, is delighted to be joined by Ryan D'Souza, MD, and Nasir Hussain, MD, following the February 2024 publication of their review, “Methodological and Statistical Characteristics of Meta-Analyses on Spinal Cord Stimulation for Chronic Pain: A Systematic Review.” Both of these anesthesiologists are prolific in their research and contributions to the regional anesthesia and pain medicine community. Best practice advisories and policies tend to stem from the results of systematic reviews and metanalysis, thus the stakes are very high for a journal to ensure that the results are meaningful and valid. The mathematical principles and assumptions of systematic reviews and meta-analyses are quite complex, which often exceeds the capacity of many journals to truly adjudicate. To further complicate matters, there are emerging techniques that include network meta-analyses that take even more expertise to review. Therefore, better understanding content areas where there are strengths and weaknesses around systematic reviews is critical to best informing clinical practice. Dr. D'Souza is a pain medicine physician and anesthesiologist at the Mayo Clinic. He is an associate professor, director of neuromodulation, and director of the in-patient pain service. He is an associate editor and social media editor for RAPM. Dr. Hussain is a pain medicine physician and anesthesiologist at the Ohio State University Wexner Medical Center. He is an assistant professor, associate program director for anesthesiology residency, and assistant program director of the chronic pain fellowship. *The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice, and it is not intended to function as a substitute for a healthcare practitioner's judgement, patient care, or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others. Podcast and music produced by Dan Langa. Find us on X @RAPMOnline, Facebook @Regional Anesthesia & Pain Medicine, and Instagram @RAPM_Online.

Сергей Маланов, доктор психологических наук. С 1991 года сотрудник Марийского государственного педагогического института им. Н.К. Крупской, с 2000 года сотрудник Марийского государственного университета, с 2017 года сотрудник Московского института психоанализа. С 1998 года под руководством А.А. Леонтьева принимал участие в научной разработке образовательной системы «Школа 2100». Научные интересы: методологические и теоретические основания психологии, психологические механизмы речевых и умственных действий человека; эволюционные и онтогенетические аспекты развития психических функций. Автор более 160 научных публикаций и книг. Среди них: Психологические механизмы мышления человека: мышление в науке и учебной деятельности. Развитие умений и способностей у детей дошкольного возраста: теоретические и методические материалы. Методологические и теоретические основы психологии. Психолингвистика: психологическая теория речевых действий. Sergey Malanov, Doctor of Psychological Sciences. Since 1991, he has been an employee of the Mari State Pedagogical Institute named after N.K. Krupskaya, since 2000 an employee of Mari State University, and since 2017 an employee of the Moscow Institute of Psychoanalysis. Since 1998, under the guidance of A.A. Leontiev, he has participated in the scientific development of the educational system "School 2100". His research interests include the methodological and theoretical foundations of psychology, psychological mechanisms of human speech and mental actions, and the evolutionary and ontogenetic aspects of the development of mental functions. He is the author of more than 160 scientific publications and books. Among them are: "Psychological Mechanisms of Human Thinking: Thinking in Science and Educational Activities," "Development of Skills and Abilities in Preschool Children: Theoretical and Methodological Materials," "Methodological and Theoretical Foundations of Psychology," and "Psycholinguistics: The Psychological Theory of Speech Actions." FIND SERGEY ON SOCIAL MEDIA VKontakte ================================SUPPORT & CONNECT:Support on Patreon: ⁠https://www.patreon.com/denofrich⁠Twitter: ⁠https://twitter.com/denofrich⁠Facebook: ⁠https://www.facebook.com/mark.develman/⁠YouTube: ⁠https://www.youtube.com/denofrich⁠Instagram: ⁠https://www.instagram.com/den_of_rich/⁠Hashtag: #denofrich© Copyright 2024 Den of Rich. All rights reserved.

In this episode of the Epigenetics Podcast, we talked with Sven Heinz from the University of California in San Diego about his work on the impact of sequence variation on transcription factor binding affinities and genetic diversity. Sven Heinz talks about a landmark study published in Nature that examined the impact of sequence variation on transcription factor binding affinities and downstream effects on gene expression. Modifying genetic sequences to understand the influence of different motifs provided valuable insights into how genetic variation shapes cellular responses and gene expression patterns, underscoring the importance of genetic diversity. Methodological approaches using inducible systems to observe changes in transcription factor binding patterns highlight the critical role of motif variation and redundancy in transcription factor families. These studies provide essential insights into the complex network of transcriptional regulation and chromatin dynamics, revealing the nuanced mechanisms that control gene expression and chromatin organization. In addition, he is investigating how small nucleotide changes can significantly affect transcription factor binding in macrophages from different mouse strains, shedding light on the intricate effects of genetic variation on transcription factor binding. Sven's career path from project scientist to assistant professor at UC San Diego and the Salk Institute reflects a journey marked by serendipitous opportunities and a collaborative, innovative research environment. The podcast delves into the effects of influenza virus infection on chromosomal territories, gene transcription, and chromatin structure, unraveling the sophisticated interplay between viral infection and host cell transcriptional regulation.   References Heinz, S., Benner, C., Spann, N., Bertolino, E., Lin, Y. C., Laslo, P., Cheng, J. X., Murre, C., Singh, H., & Glass, C. K. (2010). Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Molecular cell, 38(4), 576–589. https://doi.org/10.1016/j.molcel.2010.05.004 Heinz, S., Romanoski, C. E., Benner, C., Allison, K. A., Kaikkonen, M. U., Orozco, L. D., & Glass, C. K. (2013). Effect of natural genetic variation on enhancer selection and function. Nature, 503(7477), 487–492. https://doi.org/10.1038/nature12615 Texari, L., Spann, N. J., Troutman, T. D., Sakai, M., Seidman, J. S., & Heinz, S. (2021). An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells. STAR protocols, 2(1), 100358. https://doi.org/10.1016/j.xpro.2021.100358   Related Episodes Pioneer Transcription Factors and Their Influence on Chromatin Structure (Ken Zaret) Multiple Challenges in ChIP (Adam Blattler) The Role of Pioneer Factors Zelda and Grainyhead at the Maternal-to-Zygotic Transition (Melissa Harrison)   Contact Epigenetics Podcast on X Epigenetics Podcast on Instagram Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Epigenetics Podcast on Threads Active Motif on X Active Motif on LinkedIn Email: podcast@activemotif.com

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Three Reasons Early Detection Interventions Are Not Obviously Cost-Effective, published by Conrad K. on April 24, 2024 on The Effective Altruism Forum. Summary For pandemics that aren't 'stealth' pandemics (particularly globally catastrophic pandemics): Reason 1: Not All 'Detections' Are Made Equal: there can be significant variation in the level of information and certainty provided by different detection modalities (e.g. wastewater surveillance vs. syndromic surveillance), and the efficacy of early detection is heavily dependent on the ability to quickly trigger an epidemiological response. Thus, the nature of the detection signal is probably an important factor affecting the time required to confirm an outbreak and take action. There should probably be a greater prioritisation of plans for public health response to different types and levels of detection signals. Reason 2: 'Early' Might Not Be 'Early' (or Cheap) Enough: for highly transmissible pathogens, early detection systems may only provide a lead time on the order of days to weeks compared to "naive detection" from symptomatic spread, and the costs to achieve high confidence of detection can be prohibitively expensive (on the order of billions). Improving cost-effectiveness likely requires carefully targeting surveillance to high-risk populations and locations. Methodological uncertainties make it difficult to have high levels of confidence about how valuable early detection interventions are for a range of pathogen characteristics, particularly for GCBR-level threats. Reason 3: Response Strategies Matter, A Lot: the cost-effectiveness of early detection is highly dependent on the feasibility and efficacy of post-detection containment measures. Factors like public compliance, strength of the detection signal, degree of pathogen spread, and contingencies around misinformation can significantly impact the success of interventions. The response strategy must be robust to uncertainty around the pathogen characteristics in the early stages of a pandemic. More work is needed to ensure readiness plans can effectively leverage early detections. Background I want to start this post by making two points. Firstly, I think it is worth flagging a few wins and progress in pathogen-agnostic early detection since I began thinking about this topic roughly nine months ago: The publication of 'Threat Net: A Metagenomic Surveillance Network for Biothreat Detection and Early Warning' by Sharma et al., 2024. The publication of 'Towards ubiquitous metagenomic sequencing: a technology roadmap' by Whiteford et al., 2024. The publication of 'A New Paradigm for Threat Agnostic Biodetection: Biological Intelligence (BIOINT)' by Knight and Sureka, 2024. The publication of the preprint, 'Quantitatively assessing early detection strategies for mitigating COVID-19 and future pandemics' by Liu et al., 2023. The Nucleic Acid Observatory continued its work, publishing several notebooks, resources, white papers, reports, and preprints and even creating a tool for simulating approaches to early detection using metagenomics. The UK government published its biological security strategy in June 2023, which included goals such as the establishment of a National Biosurveillance Network and the expansion of wastewater surveillance. The U.S. Department of Health and Human Services (HHS) announced actions the department will take following National Security Memorandum 15, signed by President Biden, including accelerating advanced detection technologies. The Armed Forces Health Surveillance Division's Global Emerging Infections Surveillance branch hosted its first Next-Generation Sequencing Summit. Various funding opportunities for improving diagnostic technology were announced, including: The National Institute of Biomedical Imaging and Bioengineering'...

The sermon in this review was preached by Josh Blevins of Grace Calvary Chapel and was uploaded to Grace Calvary Chapel's YouTube page on April 14, 2023. All rights belong to Josh Blevins of Grace Calvary Chapel. This video is for teaching and review purposes only and is protected under fair use. Fair use is a doctrine in the United States copyright law that allows limited use of copyrighted material without requiring permission from the rights holders, such as commentary, criticism, news reporting, research, teaching, or scholarship. Original Sermon: https://www.youtube.com/live/QACgLkVjj4g?si=_-5HIXe4peI_x15y --- Send in a voice message: https://podcasters.spotify.com/pod/show/the-honest-yp/message

The Study of Photography in Latin America: Critical Insights and Methodological Approaches (University of New Mexico Press, 2023) provides an insider's perspective to the study of photography. Nathanial Gardner provides readers with a carefully structured introduction that lays out his unique methodology for this book, which features over eighty photographs and the insights from sixteen prominent Latin American photography scholars and historians, including Boris Kossoy, John Marz, and Ana Mauad. The work reflects the advances of the study of photography throughout Latin America with certain emphasis on Brazil and Mexico. The author further underlines the role of important institutions and builds context by discussing influential theories and key texts that currently guide the discipline. The Study of Photography in Latin America is critical to all who want to expand their current knowledge of the subject and engage with its experts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

The Study of Photography in Latin America: Critical Insights and Methodological Approaches (University of New Mexico Press, 2023) provides an insider's perspective to the study of photography. Nathanial Gardner provides readers with a carefully structured introduction that lays out his unique methodology for this book, which features over eighty photographs and the insights from sixteen prominent Latin American photography scholars and historians, including Boris Kossoy, John Marz, and Ana Mauad. The work reflects the advances of the study of photography throughout Latin America with certain emphasis on Brazil and Mexico. The author further underlines the role of important institutions and builds context by discussing influential theories and key texts that currently guide the discipline. The Study of Photography in Latin America is critical to all who want to expand their current knowledge of the subject and engage with its experts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/latin-american-studies

The Study of Photography in Latin America: Critical Insights and Methodological Approaches (University of New Mexico Press, 2023) provides an insider's perspective to the study of photography. Nathanial Gardner provides readers with a carefully structured introduction that lays out his unique methodology for this book, which features over eighty photographs and the insights from sixteen prominent Latin American photography scholars and historians, including Boris Kossoy, John Marz, and Ana Mauad. The work reflects the advances of the study of photography throughout Latin America with certain emphasis on Brazil and Mexico. The author further underlines the role of important institutions and builds context by discussing influential theories and key texts that currently guide the discipline. The Study of Photography in Latin America is critical to all who want to expand their current knowledge of the subject and engage with its experts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/art

The Study of Photography in Latin America: Critical Insights and Methodological Approaches (University of New Mexico Press, 2023) provides an insider's perspective to the study of photography. Nathanial Gardner provides readers with a carefully structured introduction that lays out his unique methodology for this book, which features over eighty photographs and the insights from sixteen prominent Latin American photography scholars and historians, including Boris Kossoy, John Marz, and Ana Mauad. The work reflects the advances of the study of photography throughout Latin America with certain emphasis on Brazil and Mexico. The author further underlines the role of important institutions and builds context by discussing influential theories and key texts that currently guide the discipline. The Study of Photography in Latin America is critical to all who want to expand their current knowledge of the subject and engage with its experts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/photography

In this episode, hosts Angus Menuge and Robert J. Marks conclude their three-part discussion with Dr. Robert Larmer about his chapter on methodological naturalism in the recent volume Minding the Brain. The trio argue that methodological naturalism is not the only viable approach in scientific inquiry and that it can be an obstruction to discovering the truth. They suggest that explanations Read More › Source

Mohammad Ghandehari is a scholar of Islamic studies. He holds a Ph.D. (on Kitāb Sulaym) from the University of Tehran, Department of Qurʾanic and Hadith Studies and is now a research fellow at the University of Religions and Denominations. His primary research interests are Early Hadith, Methodological approaches to the study of Hadith and the conversation of the Qurʾan with the Bible. His publications include “Facing Mirrors: The intertwined golden calf story” (2018). Among the courses he has taught are “The Qurʾan and the Bible” and “Early Shiʿi Hadith.”

In this episode, host Angus Menuge continues a discussion with Dr. Robert Larmer about his chapter on methodological naturalism in the recent volume Minding the Brain. In this segment of the conversation, Menuge and Larmer examine the justifications for methodological naturalism and critique some of the common arguments. They discuss the claim that non-natural causes are unknowable by scientific inquiry and Read More › Source

In this episode, hosts Robert J. Marks and Angus Menuge interview Dr. Robert Larmer about his chapter on methodological naturalism in the recently published volume Minding the Brain. Larmer explains that methodological naturalism is the assumption that when pursuing knowledge, one must always posit a physical cause and never appeal to a non-physical cause. Larmer argues that methodological naturalism is not Read More › Source

Nathalie Sinclair from Simon Fraser University in Canada discusses her article, "Knowing as remembering: Methodological experiments in embodied experiences of number," published in Digital Experiences in Mathematics Education.  Article URL https://link.springer.com/article/10.1007/s40751-023-00132-7 Nathalie's professional webpage https://www.sfu.ca/education/faculty-profiles/nsinclair.html  List of episodes

In this episode we meet Francesca Balestra and Laura Fruggeri, two of the authors of the book Psychotherapeutic competencies: Techniques, relationships, and epistemology in systemic practice (2002).  We have the opportunity to hear about the importance and value of competencies through the exploration of technical, relational, epsitimolgical and social aspects of competencies.  The episode covers:- the Methodological principles of competencies -the 4 levels of systemic competencies (technical, relational, epistemological & social) - case examples for each competency - how to develop relational skills to develop trusting relationships so change can take place - Ethics of competencies- Irreverence- Relationship between competency, context & clinical skillsBio of guests:Laura Fruggeri is a psychologist and psychotherapist and a former professor of psychology of family relationship at the University of Parma. Currently, she is the director of the Bologna Centre of Family Therapy and has been extensively teaching in the UK, Europe, and North and South America for more than 3 decades. She is the author of more than 100 publications in Italian, English, French, Spanish, Danish, and German.Francesca Balestra, PhD, is a psychologist and psychotherapist. She is a family therapist, a researcher, and a trainer at the Bologna Centre of Family Therapy. Her research interests are focused on communicative and interactive processes between therapist and client in psychotherapeutic sessions.Reference:Fruggeri, L., Balestra, F., & Venturelli, E. (2022). Psychotherapeutic competencies: Techniques, relationships, and epistemology in systemic practice. Taylor & Francis.Description of book:This book provides a clear and concise description of the multifaceted notion of psychotherapeutic competencies, building on years of research and training and informed by a systemic approach. Psychotherapeutic Competencies clearly describes methodological principles to guide both trainees and experienced therapists through the definition of four levels of systemic competencies and illustrates each principle with compelling clinical case material. The book emphasises the need for therapists to develop relational skills, which allow for the consolidation of a trusting relationship in which change can take place, as well as acquiring a set of methods and techniques. Psychotherapeutic Competencies encourages therapists of all levels of experience and therapeutic backgrounds to develop epistemological competency and to deepen their awareness of the extended contexts in which they operate and of the possible effects of their practice at a social and cultural level. This book will be essential reading for psychotherapists of all therapeutic backgrounds, in practice and in training, who wish to enhance their understanding of competency, context, and clinical skill. It will also be a key text for systemic and relational psychotherapists, trainers, trainees, clinical supervisors, and researchers.

As we send off 2023, we're releasing a series of some of our favorite episodes of the year—including some newly unlocked episodes that have previously only been available to patrons. This episode was originally released for Death Panel patrons on October 9th, 2023, and is being unlocked today for the first time. To support the show and help make episodes like this one possible, become a patron at www.patreon.com/deathpanelpod. Original description: Bea, Artie, and Abby pick apart a recent paper by Vinay Prasad, Tracy Beth Høeg, and Shamez Ladhani claiming that "methodological pitfalls" have led to the prevalence of long covid being “overestimated,” and that the problem with acknowledging high rates of long covid is that it will lead to “increased social anxiety and healthcare spending.” Find our book Health Communism here: www.versobooks.com/books/4081-health-communism Pre-order Jules' new book here: https://www.penguinrandomhouse.com/books/733966/a-short-history-of-trans-misogyny-by-jules-gill-peterson/ Death Panel merch here (patrons get a discount code): www.deathpanel.net/merch As always, support Death Panel at www.patreon.com/deathpanelpod

Subscribe on Patreon and hear this week's full patron-exclusive episode here: https://www.patreon.com/posts/90648358/ Bea, Artie, and Abby pick apart a recent paper by Vinay Prasad, Tracy Beth Høeg, and Shamez Ladhani claiming that "methodological pitfalls" have led to the prevalence of long covid being “overestimated,” and that the problem with acknowledging high rates of long covid is that it will lead to “increased social anxiety and healthcare spending.” Get Health Communism here: www.versobooks.com/books/4081-health-communism Runtime 1:44:41, 9 October 2023

In this interview, Dr. Robert Larmer joins me to discuss methodological naturalism. The discussion is based on his paper, The Prohibitive Costs of Methodological Naturalism. His Website: https://robertlarmer.com/ The Paper: https://philpapers.org/rec/LARTPC-3 You Can Contact Dr. Larmer Here: rlarmer@unb.ca -------------------------------- GIVING -------------------------------- Please consider becoming a Patron! Patreon (Thanks!): https://www.patreon.com/AdherentApologetics YouTube Membership: https://www.youtube.com/channel/UCO8jj_CQwrRRwwwXBndo6nQ/join

“Rejoice in hope, be patient in suffering, persevere in prayer” (Rom. 12). Exodus 3:1-15 Psalm 105:1-6, 23-26, 45c Romans 12:9-21 Matthew 16:21-28 1. Where is God to be found? About a hundred years ago the Austrian poet Rainer Maria Rilke (1875-1926) wrote these words, “I find you, Lord, in all Things and in all / my fellow creatures, pulsing with your life; as a tiny seed you sleep in what is small / and in the vast you vastly yield yourself. // The wondrous game that power plays with Things / is to move in such submission through the world: / groping in roots and growing thick in trunks / and in treeptops like a rising from the dead.” [1]   Yesterday I came across an old journal from October 2000 when our son was one year old. I wrote, “Micah is drinking bathwater now. He downs it like a pot-belly'd Monday night football fan at the local tavern, stands up and then coughs.” I go on to describe finding him under the microwave eating through a plastic bag of russet potatoes (and one eighth of a potato). A page later he had learned to climb by pushing his chair against the couch and walking along the back of it tightrope style. [2]   It was a pleasure to have these moments brought back to me. God seemed so present in those days of discovery, for me as a new parent, and for Micah as a new human being. James Finley offers a vision for what he calls a “contemplative way of life,” a form of existence that recognizes God as our true center. Contemplation means really looking and paying close attention. Perhaps I had more of a chance to do this when I took care of small children. [3]   Most of what we experience we notice only in passing as we are on our way to something else. But every so often we find a reason to pause. Something catches our eye. Then suddenly we find ourselves immersed in a deeper reality. We really encounter what is in front of us: a field of spring Presidio wildflowers, the billions of worlds in the summer night sky, the seemingly infinite calm dark September waters off Point Bonita, the unexpected sound of a cricket in our city or the joy of children playing.   Although these are absolutely ordinary phenomena, in each case something has broken us out of the web of worries and judgments that usually dominate our inner lives. These moments of openness almost seem to come before thought. Suddenly we become conscious, in Finley's words that, “we are the cosmic dance of God.” The fullness of being completely in God surprises us.   We might find ourselves wondering, what do I do now? Often nothing. Our cell phone summons us or a new version of an old worry occurs to us. But when we look back on times like these, we know that they felt like a kind of homecoming, like we belong there. Finley says that, “[W]hen you start understanding your life in light of these moments, you realize this feeling that you're skimming over the surface of the depths of your own life. It's all the more unfortunate because God's unexplainable oneness with us is hidden in the depths over which we are skimming.” [4]   In our disappointment, “[W]e say to ourselves, “I don't like living this way.”” [5] I don't want to be separated from the place where I most experience God's love. I want to abide with God always.   2. Moses lived in an untenable political situation. The Pharaoh had ordered his people to murder all male children of the Hebrews. Moses' parents abandoned him in a basket of reeds. The royal princess found him and raised him as her child. When Moses saw his people being brutalized he murdered a man and had to escape as a refugee. While tending his father-in-law's sheep, a sight caught Moses' attention.   An angel of the Lord appeared to him in a bush that was blazing and yet not consumed (Ex. 3). Moses said to himself, ”I must turn aside and look at this great sight” (Ex. 3). God describes a plan of liberation for the Israelites. Moses comically comes up with five excuses for why he thinks God has chosen the wrong person.   God reassures him, “I will be with you.” You will have what you need when you go to Pharoah. This is not enough for Moses. Finally Moses says, what if the Israelites ask your name. And God replies, tell them “I AM has sent me to you” (Ex. 3). Some interpreters suggest this is some kind of humor or a clever way that God avoids the question.   But for me this refers to that experience I described earlier, when our ego drops away and we feel united to our creator. It is the gratitude we feel for just being alive and to the one who brought us forth out of nothing. Where is God to be found? In the “I,” the “I AM,” beyond thought, deep within both our self and the world.   3. I spent the first part of the summer, basically in heaven, carefully reading Volume One of Katherine Sonderegger's Systematic Theology. The experience of Moses on Mount Horeb lies at the heart of her understanding of God. She begins with the idea that God is one, God is absolutely unique. Nothing is like God. We cannot think something that is absolutely unique. She writes, “God is concrete, superabundantly particular.” [6]   Sonderegger also points out that for this reason, the reality of God, especially for us in modern times, is hidden. She uses the word “omnipresence” to describe God. It does not just mean that God is everywhere but that, most often, we fail to perceive God. She says that nature in a sense hides God. And that in our time atheists help us to more deeply appreciate God's hiddenness, that “even in indifference and defiance” they in a sense glorify God. [7]   It is not just that modern universities fail to teach about God, their methods have become fully secularized. She calls this “Methodological atheism” and defines it as, “the conviction that God cannot be a reality or dimension in the principled means of knowledge in the modern intellectual world.” [8] Indeed, I would not want my rheumatologist or a Federal Reserve Bank economist appealing to God in their academic papers.   Mostly this is because, “God is not an object of our thought the way that an apple is… “God does not “stand open” and static in that way to our faculties… Yet… God will stand open to our knowledge of him as Truth.” [9]   How does this happen you might ask? At this point Sonderegger compares our experience of God with our relationships to each other. Unlike inanimate objects human beings disclose themselves to us. We know that the people we meet have an inner life. They show it to us in their words and actions. Sonderegger writes, ”We must speak or give ourselves away, in gesture or act of kindness or savage cruelty or deep intimacy.” [10]   Sonderegger writes God is lord of our knowledge of him, that in humility and like human beings, God chooses to share himself with us. One of her favorite ideas is that God is compatible with the world and us. This is part of the importance of Moses' Burning Bush for Sonderegger. God is with us.   We do not experience all of God. But God gives us a hint of transcendence in the way that the bush is burned but not consumed. God draws near and his creatures are not destroyed. God is invisible and mysterious, utterly “other” than us and yet in our midst. We know God in our inner experience.   3. In all our time together I have never shared a poem that I wrote myself. This is about a walk Micah and I took when he was a one year old. It's called “Swamp Maples.”   “In the sorrowing rain / Together we walk / Through wet autumn grass / From New England meadows / Into silent woods / And the brooding dark. // With each spongy step / I feel your weight / Shift further over / In the backpack / Until I know / You sleep.//  I worry that / The damp mist / Will make you cold. / In the corner of my eye / I see your soft angel / Face under the  navy hood. / Your tiny hand touches / My back just beneath the shoulder. / I listen for your breath / And want to wake you / From all death.”   “The fog brings / Everything closer in. / The yellowed ferns and / Ancient bark. / A million / Diamond drops / On the hemlock needles. / Until we leave the grasping roots / Of Pine Hill / For the burning colors of the lowlands. // We step through the swamp / On a thin crimson carpet / Of maple leaves / The gold leaf / ceiling above our heads / Burns with perfect brightness / Through the gray day. / The light illuminating / These trees / Seems to come from inside. // I stop to pray / My boots sinking / In black mud. / Thank you God / For all you have given / Us that we / Never could see before.” [11]   There is only one reason I am speaking to you today. There is only one thing I need to remind you. Seek God. Do not just skim over the surface of the depths of your own life. “Turn aside and look at this great sight.” “I Am” has sent you. So step away from the web of worries and judgments into a deeper reality, into the cosmic dance of God.   Help us find you Lord, “in all things and in all [our] fellow creatures pulsing with your life.”

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: New Princeton course on longtermism, published by Calvin Baker on September 2, 2023 on The Effective Altruism Forum. This semester (Fall 2023), Prof Adam Elga and I will be co-instructing Longtermism, Existential Risk, and the Future of Humanity, an upper div undergraduate philosophy seminar at Princeton. (Yes, I did shamelessly steal half of our title from The Precipice.) We are grateful for support from an Open Phil course development grant and share the reading list here for all who may be interested. Part 1: Setting the stage Week 1: Introduction to longtermism and existential risk Core Ord, Toby. 2020. The Precipice: Existential Risk and the Future of Humanity. London: Bloomsbury. Read introduction, chapter 1, and chapter 2 (pp. 49-56 optional); chapters 4-5 optional but highly recommended. Optional Roser (2022) "The Future is Vast: Longtermism's perspective on humanity's past, present, and future" Our World in Data Karnofsky (2021) 'This can't go on' Cold Takes (blog) Kurzgesagt (2022) "The Last Human - A Glimpse into the Far Future" Week 2: Introduction to decision theory Core Weisberg, J. (2021). Odds & Ends. Read chapters 8, 11, and 14. Ord, T., Hillerbrand, R., & Sandberg, A. (2010). "Probing the improbable: Methodological challenges for risks with low probabilities and high stakes." Journal of Risk Research, 13(2), 191-205. Read sections 1-2. Optional Weisberg, J. (2021). Odds & Ends chapters 5-7 (these may be helpful background for understanding chapter 8, if you don't have much background in probability). Titelbaum, M. G. (2020) Fundamentals of Bayesian Epistemology chapters 3-4 Week 3: Introduction to population ethics Core Parfit, Derek. 1984. Reasons and Persons. Oxford: Oxford University Press. Read sections 4.16.120-23, 125, and 127 (pp. 355-64; 366-71, and 377-79). Parfit, Derek. 1986. "Overpopulation and the Quality of Life." In Applied Ethics, ed. P. Singer, 145-164. Oxford: Oxford University Press. Read sections 1-3. Optional Remainders of Part IV of Reasons and Persons and "Overpopulation and the Quality of Life" Greaves (2017) "Population Axiology" Philosophy Compass McMahan (2022) "Creating People and Saving People" section 1, first page of section 4, and section 8 Temkin (2012) Rethinking the Good 12.2 pp. 416-17 and section 12.3 (esp. pp. 422-27) Harman (2004) "Can We Harm and Benefit in Creating?" Roberts (2019) "The Nonidentity Problem" SEP Frick (2022) "Context-Dependent Betterness and the Mere Addition Paradox" Mogensen (2019) "Staking our future: deontic long-termism and the non-identity problem" sections 4-5 Week 4: Longtermism: for and against Core Greaves, Hilary and William MacAskill. 2021. "The Case for Strong Longtermism." Global Priorities Institute Working Paper No.5-2021. Read sections 1-6 and 9. Curran, Emma J. 2023. "Longtermism and the Complaints of Future People". Forthcoming in Essays on Longtermism, ed. H. Greaves, J. Barrett, and D. Thorstad. Oxford: OUP. Read section 1. Optional Thorstad (2023) "High risk, low reward: A challenge to the astronomical value of existential risk mitigation." Focus on sections 1-3. Curran, E. J. (2022). "Longtermism, Aggregation, and Catastrophic Risk" (GPI Working Paper 18-2022). Global Priorities Institute. Beckstead (2013) "On the Overwhelming Importance of Shaping the Far Future" Chapter 3 "Toby Ord on why the long-term future of humanity matters more than anything else, and what we should do about it" 80,000 Hours podcast Frick (2015) "Contractualism and Social Risk" sections 7-8 Part 2: Philosophical problems Week 5: Fanaticism Core Bostrom, N. (2009). "Pascal's mugging." Analysis, 69 (3): 443-445. Russell, J. S. "On two arguments for fanaticism." Noûs, forthcoming. Read sections 1, 2.1, and 2.2. Temkin, L. S. (2022). "How Expected Utility Theory Can Drive Us Off the Rails." In L. S. ...

Well Kyle got his knickers in a bunch over an article's title so we decided to talk about it for an hour or so. Within, Johnny, Ben, Zac, and Kyle talk about how they go about screening BFR papers to decide if they deserve a closer read. The paper that got this conversation going: * Grossl, F. S., Da-Sila-Grigoletto, M. E., Ferretti, F., Copatti, S. L., Corralo, V. da S., & De-Sá, C. A. (2023). The use of a single resistance exercise with or without blood flow restriction in the treatment of pain in knee osteoarthritis: a randomized clinical trial. BrJP, ahead. https://doi.org/10.5935/2595-0118.20230023-en The first BFR paper…20 years ago…calling for individualization of pressure: * Fahs, C. A., Loenneke, J. P., & Rossow, L. M. (2012). Methodological considerations for blood flow restricted resistance exercise. Journal of. https://www.jstage.jst.go.jp/article/trainology/1/1/1_14/_article/-char/ja/ Reference for weekly volume: * Schoenfeld, B. J., Ogborn, D., & Krieger, J. W. (2017). Dose-response relationship between weekly resistance training volume and increases in muscle mass: A systematic review and meta-analysis. Journal of Sports Sciences, 35(11), 1073–1082. References for Research Procedures: * Büttner F, Toomey E, McClean S, et al Are questionable research practices facilitating new discoveries in sport and exercise medicine? The proportion of supported hypotheses is implausibly high British Journal of Sports Medicine 2020;54:1365-1371. * McCambridge, A. B., Nasser, A. M., Mehta, P., Stubbs, P. W., & Verhagen, A. P. (2021). The Journal of Orthopaedic and Sports Physical Therapy, 51(10), 503–509. * TIDieR: Hoffmann, T. C., Glasziou, P. P., Boutron, I., Milne, R., Perera, R., Moher, D., Altman, D. G., Barbour, V., Macdonald, H., Johnston, M., Lamb, S. E., Dixon-Woods, M., McCulloch, P., Wyatt, J. C., Chan, A.-W., & Michie, S. (2014). Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide. BMJ , 348, g1687. * CERT: Slade, S. C., Dionne, C. E., Underwood, M., & Buchbinder, R. (2016). Consensus on Exercise Reporting Template (CERT): Explanation and Elaboration Statement. British Journal of Sports Medicine, 50(23), 1428–1437.

Barbara M. Sattler's book The Concept of Motion in Ancient Greek Thought: Foundations in Logic, Method, and Mathematics (Cambridge UP, 2020) examines the birth of the scientific understanding of motion. It investigates which logical tools and methodological principles had to be in place to give a consistent account of motion, and which mathematical notions were introduced to gain control over conceptual problems of motion. It shows how the idea of motion raised two fundamental problems in the 5th and 4th century BCE: bringing together being and non-being, and bringing together time and space. The first problem leads to the exclusion of motion from the realm of rational investigation in Parmenides, the second to Zeno's paradoxes of motion. Methodological and logical developments reacting to these puzzles are shown to be present implicitly in the atomists, and explicitly in Plato who also employs mathematical structures to make motion intelligible. With Aristotle we finally see the first outline of the fundamental framework with which we conceptualise motion today. Professor Barbara Sattler is Chair in Ancient and Medieval Philosophy at the Ruhr University Bochum. The main area of her research is metaphysics and natural philosophy in the ancient Greek world. Morteza Hajizadeh is a Ph.D. graduate in English from the University of Auckland in New Zealand. His research interests are Cultural Studies; Critical Theory; Environmental History; Medieval (Intellectual) History; Gothic Studies; 18th and 19th Century British Literature. YouTube channel. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Barbara M. Sattler's book The Concept of Motion in Ancient Greek Thought: Foundations in Logic, Method, and Mathematics (Cambridge UP, 2020) examines the birth of the scientific understanding of motion. It investigates which logical tools and methodological principles had to be in place to give a consistent account of motion, and which mathematical notions were introduced to gain control over conceptual problems of motion. It shows how the idea of motion raised two fundamental problems in the 5th and 4th century BCE: bringing together being and non-being, and bringing together time and space. The first problem leads to the exclusion of motion from the realm of rational investigation in Parmenides, the second to Zeno's paradoxes of motion. Methodological and logical developments reacting to these puzzles are shown to be present implicitly in the atomists, and explicitly in Plato who also employs mathematical structures to make motion intelligible. With Aristotle we finally see the first outline of the fundamental framework with which we conceptualise motion today. Professor Barbara Sattler is Chair in Ancient and Medieval Philosophy at the Ruhr University Bochum. The main area of her research is metaphysics and natural philosophy in the ancient Greek world. Morteza Hajizadeh is a Ph.D. graduate in English from the University of Auckland in New Zealand. His research interests are Cultural Studies; Critical Theory; Environmental History; Medieval (Intellectual) History; Gothic Studies; 18th and 19th Century British Literature. YouTube channel. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/mathematics

Barbara M. Sattler's book The Concept of Motion in Ancient Greek Thought: Foundations in Logic, Method, and Mathematics (Cambridge UP, 2020) examines the birth of the scientific understanding of motion. It investigates which logical tools and methodological principles had to be in place to give a consistent account of motion, and which mathematical notions were introduced to gain control over conceptual problems of motion. It shows how the idea of motion raised two fundamental problems in the 5th and 4th century BCE: bringing together being and non-being, and bringing together time and space. The first problem leads to the exclusion of motion from the realm of rational investigation in Parmenides, the second to Zeno's paradoxes of motion. Methodological and logical developments reacting to these puzzles are shown to be present implicitly in the atomists, and explicitly in Plato who also employs mathematical structures to make motion intelligible. With Aristotle we finally see the first outline of the fundamental framework with which we conceptualise motion today. Professor Barbara Sattler is Chair in Ancient and Medieval Philosophy at the Ruhr University Bochum. The main area of her research is metaphysics and natural philosophy in the ancient Greek world. Morteza Hajizadeh is a Ph.D. graduate in English from the University of Auckland in New Zealand. His research interests are Cultural Studies; Critical Theory; Environmental History; Medieval (Intellectual) History; Gothic Studies; 18th and 19th Century British Literature. YouTube channel. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/intellectual-history

Barbara M. Sattler's book The Concept of Motion in Ancient Greek Thought: Foundations in Logic, Method, and Mathematics (Cambridge UP, 2020) examines the birth of the scientific understanding of motion. It investigates which logical tools and methodological principles had to be in place to give a consistent account of motion, and which mathematical notions were introduced to gain control over conceptual problems of motion. It shows how the idea of motion raised two fundamental problems in the 5th and 4th century BCE: bringing together being and non-being, and bringing together time and space. The first problem leads to the exclusion of motion from the realm of rational investigation in Parmenides, the second to Zeno's paradoxes of motion. Methodological and logical developments reacting to these puzzles are shown to be present implicitly in the atomists, and explicitly in Plato who also employs mathematical structures to make motion intelligible. With Aristotle we finally see the first outline of the fundamental framework with which we conceptualise motion today. Professor Barbara Sattler is Chair in Ancient and Medieval Philosophy at the Ruhr University Bochum. The main area of her research is metaphysics and natural philosophy in the ancient Greek world. Morteza Hajizadeh is a Ph.D. graduate in English from the University of Auckland in New Zealand. His research interests are Cultural Studies; Critical Theory; Environmental History; Medieval (Intellectual) History; Gothic Studies; 18th and 19th Century British Literature. YouTube channel. Learn more about your ad choices. Visit megaphone.fm/adchoices

Navigating Your Investment Portfolio Review: From High-Level Goals to Methodological DetailsWelcome to "Your Investment Partners" with Paul and Garrett! In this episode, we delve into the crucial aspects to consider during your investment portfolio review. It's easy to get lost in the details, but we believe starting from a high-level perspective, and focusing on your goals, leads to greater clarity and alignment. Whether you're preparing for an investment review meeting or examining your statement, this episode will provide valuable insights to guide your decision-making process.Key Points:The importance of approaching investment portfolio reviews from a holistic perspectiveStarting with big-picture goals and objectives for a clearer investment strategyUnderstanding time horizons and their impact on investment decisionsBalancing risk tolerance with long-term financial planningAvoiding knee-jerk reactions to short-term performance issuesThe current market landscape and its effect on conservative stocksSeeking value and attractive valuations as a long-term investment approachJoin us as we discuss the considerations you should have in mind during your investment portfolio review. We provide expert advice, share practical tips, and offer insights to help you make informed decisions that align with your financial goals.Have questions or thoughts to share? We encourage you to reach out to us and be part of the conversation. Don't miss out on this episode, packed with valuable information to enhance your investment portfolio management.Tune in now to gain clarity, align your investment goals, and make informed decisions for a secure financial future.

Imagine building a cathedral with just a hammer and nails. How might theologians today continue to build the grand cathedral where human knowledge meets divine revelation by implementing the tools of psychological science? Experimental psychologist Justin Barrett joins theologian Miroslav Volf for a conversation on how psychology can contribute to theology. This episode is made possible by Blueprint1543.IntroductionTo a man with a hammer, everything looks like a nail. Yep, we've heard that before. But imagine trying to make that work. Imagine, for instance, the visionary builder of a medieval cathedral… building it only with a hammer and nails.And you know there's an analogy coming here. Suppose the cathedral you're trying to build is nothing less than the human inquiry into the nature of the cosmos and the nature of the God who created them—from the dark matter at the edges of the expanding universe, to the recycled space dust that's found its way into the pristine fingernails of a newborn baby.Artfully articulating the nature of reality with nuance and care—saying something true and meaningful about God, people, and thriving in the world we share—the task of theology could be just like that extravagant building project.But imagine if the theologian only had one tool.Experimental psychologist Justin Barrett tells a story like this to make a suggestion to theologians to consider how they might incorporate the tools of science—and psychological science in particular—into the building of their theological cathedral.Justin is long-time researcher in cognitive science of religion. He's author of a number of books, including Why Would Anyone Believe in God? and Born Believers: The Science of Childhood Religion. He just edited the Oxford Handbook of the Cognitive Science of Religion.And in 2019 he co-founded Blueprint1543, an organization that's bringing theologians and scientists together to accelerate better contributions to life's biggest questions.And today we're launching a series of episodes on For the Life of the World that will explore the tools of psychological sciences that might contribute to a deeper and greater theological understanding of the world. By bringing a science-engaged theology to bear on the most pressing matters for how to live lives worthy of our humanity.Throughout the series, we're featuring conversations with psychologists who can offer insightful tools for crafting the cathedral where human knowledge meets divine revelation.About Justin BarrettJustin L. Barrett is an honorary Professor of Theology and the Sciences at St Andrews University School of Divinity. An experimental psychologist by training, he is concerned with the scientific study of religion and its philosophical as well as theological implications. He is the author of a number of books including Why Would Anyone Believe in God?, Born Believers: The Science of Childhood Religion, and Religious Cognition in China: Homo Religiosus and the Dragon.Show NotesBlueprint1543.orgDownload your copy of Justin Barrett's A Psychological Science Primer for Theologians (2022)TheoPsych AcademyNormative vision the good lifePsychology as among the most secular of academic disciplinesPsychology's historical (but non-necessary) anti-religious tendenciesThere are plenty of Christian psychologists who are deliberate in thinking about the integration of Christianity and psychologyComparing instrumental, explanatory psychology and purposes, meaning, and teleology in theologyHow the purposes of our lives—normative visions—how do they then shape psychological inquiryAre questions of the good life matters for science to determine, or are religious and theological perspectives essential to thinking about the purpose and meaning of human life?When can theologians and philosophers be helped by psychological science?Theologians often make use of psychological claims fairly uncritically—how human minds work, how emotions work, how social relationships workMiroslav's book The End of MemoryIs the theologian making descriptive psychological claims?Are you the theologian making normative claims supported by descriptive psychological claims?Are you making claims about what affects texts and rituals and practices have on people?Are you constructing an argument that uses intuition as premises?Experimental philosophy: Are philosophers' intuitions universal?Can there be an “experimental theology”?Being careful about descriptive psychological claims—especially for practical theological questions or lived theologyPsychology needs to do its own inspecting“The science of psychology has a great self-awareness of how we can't trust ourselves. … The entire method is built around, to put it in theological terms, a conviction about total depravity.”Methodological rigor in sciences—checking findings with the communityCultural situatednessE.g., “How well do we know ourselves?”Ludwig Wittgenstein: “The world of a happy man is not the same as the world of a sad man.”“Affective states shape how we perceive the world.”Mary Magdalene's breaking a precious jar or oil on Jesus's feet—the smell is refracted through how Judas and Jesus see the world. Judas finds the smell a terrible waste, and Jesus finds the smell beautiful.“What we perceive in the world around us is set by our expectations.”“Every Christian is a theologian because theology accompanies the life and situatedness of each individual in the world.”Production NotesThis podcast featured cognitive scientist Justin Barrett and theologian Miroslav VolfEdited and Produced by Evan RosaHosted by Evan RosaA Production of the Yale Center for Faith & Culture at Yale Divinity School https://faith.yale.edu/aboutSupport For the Life of the World podcast by giving to the Yale Center for Faith & Culture: https://faith.yale.edu/giveAcknowledgementsThis episode was made possible in part by the generous support of Blueprint 1543. For more information, visit Blueprint1543.org.

Bradyarrhythmia during AF screening, thrombolysis in stroke, NP vs MD care, and the most biased paper this year — on LAAO — are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Screening with ILR - Ade Adamson Tweet https://twitter.com/AdeAdamson/status/1625878856820482048?s=20 - The Rapid Rise in Cutaneous Melanoma Diagnoses https://www.nejm.org/doi/full/10.1056/NEJMsb2019760 - Loop Trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01698-6/fulltext - Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care https://jamanetwork.com/journals/jamacardiology/fullarticle/2801362 II. Thrombolysis in Mild Stroke Thrombolysis Not Necessary in Mild Nondisabling Stroke: ARAMIS https://www.medscape.com/viewarticle/988381 - PRISMS Trial https://jamanetwork.com/journals/jama/fullarticle/2687354 - Risk of selection bias assessment in the NINDS rt-PA stroke study https://pubmed.ncbi.nlm.nih.gov/35705913/ - Tissue Plasminogen Activator for Acute Ischemic Stroke https://www.nejm.org/doi/full/10.1056/NEJM199512143332401 - Effects of alteplase for acute stroke; Hacke et al meta-analysis https://journals.sagepub.com/doi/10.1177/1747493017744464 - Methodological survey of missing outcome data in an alteplase for ischemic stroke meta-analysis https://onlinelibrary.wiley.com/doi/full/10.1111/ane.13656 - ECASS; Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke https://www.nejm.org/doi/full/10.1056/nejmoa0804656 - Thrombolysis with alteplase 3-4.5 hours after acute ischaemic stroke: trial reanalysis adjusted for baseline imbalances https://pubmed.ncbi.nlm.nih.gov/32430395/ III. NP vs MD Care This Doc Still Supports NP/PA Led Care ... With Caveats https://www.medscape.com/viewarticle/967073 - The Productivity of Professions: Evidence from the Emergency Department https://www.nber.org/papers/w30608 - Independent Nurse Practitioners and Physician Assistants: A Doc's View https://www.medscape.com/viewarticle/924047 IV. LAAO vs OAC - Comparative Effectiveness of Left Atrial Appendage Occlusio Versus Oral Anticoagulation by Sex https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062765 You may also like: Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

John Haar from Swan Private joins me on the show to chat about his journey working inside the TradFi machine and coming to see Bitcoin as the answer: Being a goldbug Reading and learning at mises.org Methodological differences with mainstream economics Full Reserve and Fractional Reserve thoughts Will we see Bitcoin decorrelation? Inflation Links: Article: How Legacy Finance Perceives Bitcoin Twitter: @john_at_swan Prior episodes: SLP402 Pierre Rochard – Bitcoin Obsoletes Fractional Reserve Banking Prior episodes: SLP266 Croesus_BTC – Bitcoin: Stake Your Claim Before Everyone Else Prior episode: SLP416 Per Bylund – How To Think About Economics Sponsors: Swan Bitcoin Mempool.space Braiins.com Unchained Capital (code LIVERA) CoinKite.com(code LIVERA) Stephan Livera links: Follow me on Twitter @stephanlivera Subscribe to the podcast Patreon @stephanlivera