Podcasts about blood vessels

Our main feature is Evil Dead Burn. We're also reviewing Deep Water, Destroy All Monsters, Blood Vessel, Ushers by Joe Hill, Conspiracies by F. Paul Wilson, and more. Deep Water ► https://amzn.to/4phgu72 Destroy All Monsters ► https://amzn.to/4vZUcJB Blood Vessel ► https://amzn.to/4wIFgzp Ushers by Joe Hill ► https://amzn.to/4pj6gTM Conspiracies by F. Paul Wilson ► https://amzn.to/4gEgvzM

If you'd like to skip ahead to the short story, it starts at 16:30. ^_^

This episode outlines my PhD thesis, as well as explaining how the following nine "Blood Vessel" stories serve as an example of Goodnight, Witch Academy's structure. 

Ronald White, guest author, recounts how, in June 1864, Chamberlain led a perilous frontal assault at Petersburg, where he was struck by a minié ball that traveled through his hips, shattering internal blood vessels and his bladder. Surgeons gave him only a 10% chance of survival, and he wrote a heart-wrenching final farewell to Fanny from his hospital bed. Defying medical expectations, he survived the infection-riddled environment and returned to the field to command a brigade during the final pursuit of Lee's army. At Appomattox, General Grant chose him to preside over the formal surrender ceremony of the Confederate infantry. During this event, Chamberlain sparked decades of controversy by ordering a "marching salute" to the defeated Southern soldiers to honor their courage. This act of reconciliation underscored his belief that the war's end required bringing both sides back together as one nation despite the deep scars of conflict. On Great Fields: The Life and Unlikely Heroism of Joshua Lawrence Chamberlain (4)1864

Why is Europe experiencing a heatwave? What happens if a being from a different dimension enters our dimension? Why are wombats able to produce square-shaped faeces? Can we live without sodium? Is there a scientific explanation for xenophobia? Why did the Lincoln Memorial Reflecting Pool turn into a green swamp? What causes early morning phlegm, even without a cold? Dr Chris Smith and Clarence Ford have the answers... Like this podcast? Please help us by supporting the Naked Scientists

Why is Europe experiencing a heatwave? What happens if a being from a different dimension enters our dimension? Why are wombats able to produce square-shaped faeces? Can we live without sodium? Is there a scientific explanation for xenophobia? Why did the Lincoln Memorial Reflecting Pool turn into a green swamp? What causes early morning phlegm, even without a cold? Dr Chris Smith and Clarence Ford have the answers... Like this podcast? Please help us by supporting the Naked Scientists

What if the blood vessels in your brain aren't just collateral damage in Alzheimer's disease, but part of the cause?Dr. Rachel Bennett, associate professor at Massachusetts General Hospital and Harvard Medical School, is challenging one of the field's longest-held assumptions. In this episode, she joins host Deborah Westfall to break down her groundbreaking research on the relationship between tau pathology and vascular dysfunction, and why the future of Alzheimer's science may look nothing like what we expect today.What You'll Learn in This EpisodeWhy vascular changes in Alzheimer's disease were historically treated as secondary damage, and why that thinking is shiftingHow Dr. Bennett's lab discovered that tau pathology alone can drive abnormal changes in blood vessel structureThe thick-tissue imaging technique that revealed something thin slides had been missing for decadesWhat 47 meters of blood vessels in a single brain fold tells us about the scale of this problemWhy the field may be drastically underestimating the number of distinct Alzheimer's disease subtypesHow AI and spatial transcriptomics are accelerating discoveries that would have taken years under traditional funding timelinesThe critical role of philanthropic funding for early-career researchers, and why smaller, faster grants can outperform traditional NIH timelinesAbout Dr. Rachel BennettDr. Rachel Bennett is an associate professor at Massachusetts General Hospital and Harvard Medical School, and a 2024 and 2025 Toffler Scholar. She runs the Bennett Alz Lab, which focuses on vascular contributions to Alzheimer's disease using cutting-edge imaging techniques including light sheet microscopy, in vivo two-photon microscopy, and spatial transcriptomics. She completed her PhD at Washington University in St. Louis studying traumatic brain injury and microglia, and her postdoctoral training in the lab of Dr. Bradley Hyman at MGH.Resources and LinksBennett Alz Lab: bennettallzlab.comConnect with Dr. Bennett on LinkedInKaren Toffler Charitable Trust: karrentoffler.orgMassachusetts Alzheimer's Disease Research Center (Massachusetts ADRC)Research referenced: Acta Neuropathologica (tau and vascular accumulation study)If this episode opened your eyes to a new side of Alzheimer's research, please leave a review on Apple Podcasts or Spotify. Share it with someone who cares about brain health, and subscribe so you never miss an episode of Research Renaissance.To learn more about the breakthroughs discussed in this episode and to support ongoing research, visit our website at tofflertrust.org. Technical Podcast Support by Jon Keur at Wayfare Recording Co.

What if the real driver of aging isn't your mitochondria or your telomeres but the tiny capillaries you never think about? Double board-certified emergency and internal medicine physician Kenneth Ro returns to the show to make a compelling case that microvascular decline is the overlooked upstream force behind nearly every disease of aging. In this episode, based on his KevinMD article "How the microvasculature drives the human aging process," he explains why your body shuts down capillaries you stop using through a process called capillary rarefaction, and how that quietly starves tissues of oxygen long before symptoms appear. You will hear how microvascular disease connects diabetic complications, heart failure with preserved ejection fraction, and even sepsis under one unifying framework. He also shares why exercise works at a level deeper than most clinicians discuss, what GLP-1 agonists may be doing to your pericytes, and why VO2 max and heart rate variability are your best windows into microvascular health. This episode will change how you think about what it truly means to age well. Tune into our episode "2026 Cholesterol Guidelines: LDL goals, lipoprotein(a), and coronary calcium scoring," brought to you by Novartis Pharmaceuticals Corporation. For the first time in eight years, LDL cholesterol goals have changed, and preventive cardiologist Seth Baum says the new guidelines are a long-overdue course correction. He breaks down the new LDL targets for your highest-risk patients, why the LDL hypothesis should be retired in favor of the LDL fact, why lipoprotein(a) screening finally belongs in every patient's workup, what a coronary calcium score over 300 really means for how aggressively you treat, and how to talk to statin-skeptical patients without losing their trust. Listen now at KevinMD.com/cholesterol. VISIT SPONSOR → https://kevinmd.com/cholesterol Partner with me on the KevinMD platform. With over three million monthly readers and half a million social media followers, I give you direct access to the doctors and patients who matter most. Whether you need a sponsored article, email campaign, video interview, or a spot right here on the podcast, I offer the trusted space your brand deserves to be heard. Let's work together to tell your story. PARTNER WITH KEVINMD → https://kevinmd.com/influencer SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended

EECP Therapy and Stroke Recovery: Can a Cardiac Treatment Help Grow New Blood Vessels? When I first heard about EECP therapy in the context of stroke recovery, I was skeptical. It’s a cardiac device approved in Australia for stable angina and congestive heart failure. Stroke is not on the label. So why are we talking about it on a stroke recovery podcast? Because the mechanism is fascinating. And the research, while still emerging, is pointing somewhere worth paying attention to. In this episode, I sat down with Jack Clifford, a heart disease patient who discovered EECP therapy and began exploring its potential beyond its approved indications. What started as a cardiac conversation quickly became one of the most scientifically interesting discussions I’ve had on the show. What Is EECP Therapy? EECP stands for Enhanced External Counterpulsation. The treatment involves a set of pneumatic cuffs fitted around the calves, thighs, and buttocks. These cuffs inflate and deflate in precise synchrony with the heartbeat, inflating during the heart’s resting phase (diastole) to push blood back toward the heart, and deflating just before the heart contracts. The result is an increase in blood flow and a specific type of fluid shear stress on blood vessel walls. It’s that shear stress that makes things interesting. The Biology: Arteriogenesis and Angiogenesis To understand why EECP therapy might be relevant to stroke survivors, you need to understand two terms: angiogenesis and arteriogenesis. Angiogenesis is the sprouting of entirely new capillary vessels — the body builds small blood channels where none existed before. Arteriogenesis is different: it’s the remodelling of pre-existing, dormant collateral vessels into functional bypass channels. Think of it like upgrading a dirt track into a highway. The track was always there; the body just wasn’t using it. When blood flow is obstructed, whether by a blocked coronary artery or a stroke, the body can, under the right conditions, activate these collateral pathways. The shear stress produced by EECP therapy appears to be one of the triggers that stimulate arteriogenesis. By generating repeated waves of increased blood flow, the treatment creates the mechanical signal that tells blood vessel walls to grow and remodel. This is why cardiac researchers originally developed EECP for heart patients. But it raises a legitimate scientific question: could the same mechanism support blood flow recovery in the brain after stroke? What Does the Research Say? A 2026 meta-analysis published in the QJM: An International Journal of Medicine examined 15 randomized controlled trials involving 506 participants, looking specifically at EECP’s effects on functional outcomes in stroke patients. The results showed statistically significant improvements, with EECP outperforming control conditions on standard functional recovery measures. This is preliminary evidence, not a settled clinical consensus. The studies are relatively small, the methodology varies across trials, and EECP remains off-label for stroke in Australia. But for a therapy with a well-understood safety profile and an existing approval framework, 15 studies and 506 participants is not nothing. It’s enough to warrant serious discussion. What I Discussed with Jack Clifford Jack came to EECP as a patient, not a researcher. His experience with heart disease led him to explore the therapy, and he’s spent considerable time understanding the evidence base and connecting with practitioners. He’s not a clinician, and neither am I, but what we can do together is examine what the research actually says, what the mechanism actually is, and what questions remain unanswered. In our conversation, we discussed: How Jack first encountered EECP therapy and what led him to investigate it further The difference between approved and off-label use, and why that distinction matters What the shear stress mechanism actually looks like in practice The existing network of EECP practitioners and how stroke survivors might access the therapy The questions both of us still have about where the research needs to go Important Disclaimers   EECP therapy is approved in Australia by the TGA for stable angina pectoris and congestive heart failure (ARTG Entry 376470). Stroke is NOT an approved indication. This article and podcast episode are not medical advice. Speak with your treating physician before pursuing any treatment. This episode is not medical advice. It is a conversation about an area of emerging research that I find scientifically credible and worth understanding. The goal is to help you ask better questions, not to tell you what treatment to pursue. Where to Learn More ecplocator.com a directory of EECP therapy providers eecpbook.com is a dedicated resource on the treatment and its evidence base recoveryafterstroke.com for stroke survivors looking for a broader community Research cited: Zhao et al. (2026). Enhanced external counterpulsation for ischaemic stroke: a systematic review and meta-analysis. QJM: An International Journal of Medicine. DOI: 10.1093/qjmed/hcag010. Therapy and Stroke Recovery: Can a Cardiac Treatment Help Grow New Blood Vessels? Bill Gasiamis sits down with Jack Clifford to explore EECP therapy, a TGA-approved cardiac treatment that may stimulate the growth of new blood vessels. Together, they examine the emerging research on angiogenesis, arteriogenesis, and whether this off-label approach holds promise for stroke survivors seeking to improve blood flow to the brain. Highlights: 00:00 Introduction – EECP Therapy06:06 Recognizing Health Issues and Seeking Help09:50 Hospital Experience and Heart Health12:12 Decisions Against Medical Advice16:28 Exploring Alternative Treatments18:06 Understanding Enhanced External Counter Pulsation (EECP)21:58 The Mechanism of EECP27:03 Personal Transformation Through EECP30:29 Lifestyle Changes and Holistic Health34:35 The Impact of Stress on Health38:30 The Journey of Writing a Book43:29 The Role of EECP in Heart Health48:21 Raising Awareness for EECP Therapy56:05 Exploring the Future of EECP Therapy Transcript: Introduction – EECP Therapy Jack Clifford (00:00)Mine was really severe. 100 % blocked in my widow maker, the left anterior descending. I’m 95 in my left coronary artery and in my right main, I am 80%. And I’m still that way today, but I can run a sub seven mile. Bill Gasiamis (00:16)Welcome to the Recovery After Stroke podcast. I am your host, Bill Gassiamus. Before we get into today’s interview, I need to share something important. The topic we’re exploring today involves a medical device called an EACP, Enhanced External Counterpulsation Machine. In Australia, EACP is registered with the Therapeutic Goods Administration for the treatment of stable angina and congestive heart failure. It is not approved for stroke. What we are discussing today is emerging off-label research, not a treatment recommendation. Everything in this episode is for informational purposes only. This is not medical advice. Please speak with your treating physician before pursuing any treatment, therapy or intervention discussed here. With that said, let’s talk about something that genuinely fascinated me when I started reading the research. Your body has the capacity to grow new blood vessels, not just small capillaries, but to remodel dormant pre-existing channels into functional bypass routes. Scientists call this arteriogenesis. There’s also angiogenesis, the sprouting of entirely new Both processes matter deeply for stroke because stroke is fundamentally a blood flow problem. Now here’s where it gets interesting. A cardiac therapy developed for heart patients, not stroke patients, trigger exactly this kind of vascular remodeling. And in 2026, a meta-analysis published in the QJM across 15 randomized controlled trials and 506 participants found that EECP produced statistically significant improvements in functional outcomes for ischemic stroke patients. Now, that’s not proof. That’s not a green light to go and get an EECP, but it is worth a serious conversation. My guest today is Jack Clifford. Jack is a heart disease patient who discovered EECP therapy while managing his own cardiac condition and who has since spent considerable time investigating its potential. beyond cardiac care. I should tell you, I was skeptical going into this conversation, but I’ve learned that skepticism without curiosity isn’t really skepticism. It’s just closed mindedness. So I read the research and then I sat down with Jack. So if you find this episode valuable, I’d love for you to grab a copy of my book, The unexpected way that a stroke became the best thing that happened at recoveryafterstroke.com/book. And if you want to support the show, you can join Patreon at patreon.com/recoveryafterstroke. And I want to thank everyone who is supporting me on Patreon, especially the people that have been around for a long time and the people who have just recently signed up. I very much appreciate it. And now here’s my conversation with Jack Clifford. Bill Gasiamis (03:19)Welcome to the podcast. Jack Clifford (03:22)Thanks, Bill. Great to be here. Bill Gasiamis (03:24)Let’s give the listeners a bit of a background understanding of why you’re on the podcast. You’re not a stroke survivor, but we have something in common as ⁓ somebody who has been unwell before myself and you in the past. Tell me a little bit about your journey to the podcast So we just kind of give people an understanding as to how it is that somebody who’s not a stroke survivor. Jack Clifford (03:34)We do. Bill Gasiamis (03:51)how we ended up chatting together? Jack Clifford (03:54)Yeah, absolutely. So the quick version here is ⁓ I was on the brink five years ago of having ⁓ unsentable emergency triple bypass surgery. And ⁓ I chose a different path, which we’ll get to. ⁓ But you you have some level of placking if you have a stroke, typically, depends on the stroke, but that’s typically the case. And in my case, I had placking in my coronary arteries. So it resulted in heart disease. Mine was really severe. 100 % blocked in my widow maker, the left anterior descending. ⁓ I’m 95 in my ⁓ left coronary artery and in my right main, I am 80%. And I’m still that way today, but I can run a sub seven mile. I can do some things that a guy that’s as blocked up as that should not theoretically be able to do. ⁓ Bill Gasiamis (04:49)All right. Tell me about life before the injury. What kind of work did you do? How did you go about life? What was generally a day like for you? Jack Clifford (04:59)Yeah. So I’m retired military guy. Um, so, you know, been in the military most of my life, um, retired about 10 years ago, a little over that. And, um, so I’ve always been a pretty fit guy. It wasn’t, you know, it wasn’t a fitness issue per se. Um, and, uh, I, I, I had kind of lost some of my self care because my wife had been going through some real significant medical issues that really required my full attention for quite a while. And because of that, really stopped taking care of myself in the ways I had in the past for about 10 years. And when we had just moved to Florida, I started trying to take care of myself again. And that’s when I discovered all these problems. Bill Gasiamis (05:44)So what does not taking care of yourself look like though? Jack Clifford (05:47)Gotta be in a couch potato and being on my computer way too much research and for ⁓ trying to help my wife get better and hold down a job at the same time and raise a family and all these other things that took the priority off of me in that sense that one should be taking care of themselves, meaning exercising, meaning eating the right foods, so on and Recognizing Health Issues and Seeking Help Bill Gasiamis (06:09)You know, caregivers tend to die before the person they’re caring for much more often. And it’s cause of that reason, right? Because time is really taken up by especially full-time caregiving with somebody’s in the house and they need caregiving. need care. The caregiver tends to neglect themselves in every way, shape and form and tends to ⁓ make it about the other person. And then the other person. Jack Clifford (06:14)I’ve seen that and heard about it. Yeah. Mm-hmm. Bill Gasiamis (06:39)seems to be doing okay, but the caregiver is struggling and doesn’t ask for help and doesn’t go and doesn’t go and get looked after. And then things tend to catch up with them and they become the ⁓ sickest person in that relationship. Jack Clifford (06:55)It’s like that whole put your oxygen mask on first on the airplane type thing, right? Like, you know, we can’t we can’t give what we don’t have to give Bill Gasiamis (07:01)Uh-huh. Yeah. So you, did you notice, did you notice the steady decline in your health? Did you kind of go, I’m not feeling right. I’m a feel a bit sluggish like 10 years down the track, or did it just creep up on you? then you got to this point. Jack Clifford (07:15)It really crept, it really crept. I, you know, like I had initially exercise induced angina, but it wasn’t much exercise that induced the angina. And then it very quickly progressed to trying to walk and getting out of breath and, know, at very basic walking speeds, just moderately paced, you know, anything anybody would do out in your neighborhood. ⁓ Bill Gasiamis (07:39)Did you know that you had an angina? Jack Clifford (07:41)I did, yeah. I didn’t have a big heart attack episode like some people have. I’m 100 % blocked. There’s no heart attack to happen, right? Because the stuff is, I’m so blocked that it’s just a pure blood flow issue. A lot of people don’t understand that that 50 % blockage is a huge risk for a heart attack because you’re gonna burst a plaque and then go from 50 % to 100 % like that. But you know about collaterals. And if you have collaterals in place, the blood’s not getting flowing this way, you’re gonna recruit some lead oval collaterals to be able to just get by with your activities of day living. But if you don’t push yourself, you don’t know that you don’t have enough blood flow to do these other things. Bill Gasiamis (08:22)Okay, so you got to the point where you were so unwell as far as the blood vessels around your heart were so unwell, they were so blocked that angina led to another escalation or something happened that got you to the point where you realized, okay, things are not good. Now, tell me what angina is exactly and what it’s like to have it. How do you experience it? Jack Clifford (08:39)Yeah. yeah, yeah. I’d love to talk about that. Bill. at its most basic, it’s a supply demand mismatch. So, you know, the blood flow that’s supplying your heart ⁓ is adequate for X, Y, or Z activities of daily living. You know, walking around the house, doing the dishes, you might have enough blood flow for that, but you don’t have enough blood flow to go run a mile or even walk potentially, you know, or Hospital Experience and Heart Health but it’s all about supply demand mismatch. And that’s about just the size of the pipes, you know, if they’re clogged up, how clogged up are they? And, know, ⁓ that’s, really it. So, and what it feels like is it’s scary because it feels like a heart attack. all like, what does a heart attack feel like? Well, there’s a thousand different sort of, ⁓ descriptions of it. ⁓ you know, radiating down your arm or nausea or something in your back, but. you know, if it’s right over your heart, it’s unmistakable. And that’s at least my presentation of angina. And I think it was a pretty typical one is, you know, I have this weird kind of deep pain. initially, when I, when I started, you know, run, trying to run and got it, I thought, ⁓ you know, I just pulled a chest muscle weirdly over my heart. You know, I’ll stop and let’s see if it goes away. I come back, you know, no, same thing. Okay. Still not better. Let’s do it again. Another couple of days later, so on and so forth. I was just kidding myself, but I didn’t know anything about the horror at that point. hadn’t had to research all this stuff and do all the deep dive. Bill Gasiamis (10:16)That’s the same crazy logic that stroke survivors put to, I’m feeling weird. I’m dizzy. I’m going to go and lie down. I’m going to rest. It’ll be better later. ⁓ I’m too busy. I’ve got to go to work. ⁓ I’ve even had stroke survivors where somebody’s telling them you maybe you’re having a stroke, you know, just tongue in cheek and they’re like, yeah, no, probably not. ⁓ it’s the same crazy logic that we say about things that are unfamiliar to us that we cannot potentially. Jack Clifford (10:25)Mm-hmm. Mm-hmm. Yeah. Yeah. Bill Gasiamis (10:46)link to something so serious because we have no knowledge, we’re ignorant, right? Jack Clifford (10:47)Yeah. Well, yeah, I think that’s really part of the key there is like most times with something as sudden as what you’re talking about or what I’m talking about in my instance, because it was pretty, pretty sudden, you know, weeks and months. ⁓ We went from being these, you know, healthy people that felt like we were on top of the world to all of a sudden not. you you didn’t have a frame for what not looked like. ⁓ Bill Gasiamis (11:14)Exactly. Yeah. That’s such an important comment. We don’t have the frame for what not healthy looks like and therefore you don’t know what you don’t know. So you don’t take any action. You just brush it off. Okay. I hear you. All right. We got to the bottom of the stupidity behind a lot of my decisions as well to avoid going to hospital for a week, et cetera, the first time. ⁓ So you end up Jack Clifford (11:24)Exactly. That’s it. Bill Gasiamis (11:43)being really unwell on this particular date. Kind of what is that day like? Explain us. Jack Clifford (11:46)Yeah. Yeah. Decisions Against Medical Advice So I got tight. I, I, I’ve been a biohacker for a while. So that’s probably the only reason I’m here talking to you because I went off the beaten path really far off the beaten path to get to the place where I know what I know and I have to share what I have to share. ⁓ because I’ve been trying to help my wife get better for some significant issues, including a really bad traumatic brain injury. And some other things and doctors didn’t have the answers for those so we had to we had to kind of biohack our way out of some things I was comfortable back. I’m saying that to say my wife got me a Chili pad for my bed because you know been trying to biohack sleep for a while and the colder environments to sleep are you know better to some degree at least in theory ⁓ and so Yeah, correct Bill Gasiamis (12:32)Chili meaning cold, not spicy. Jack Clifford (12:37)Yeah, correct. A chili pad as in the cold. So it’s a device that just, you know, cools your bed off. And so I crank that down to 55. She got it for me for Christmas. So Christmas day Eve, I’m like hopping into bed, like I’m going to sleep really well tonight, you know, and I woke up at four AM like, Oh, you know, I thought that was the big one because it felt that way. I a dead sleep woke me up with, with intense chest pain. And I knew something was going on, you but I was kidding myself. I hadn’t talked to family about it. You know, I hadn’t shared anything about what was going on with anybody. So at this point I’m like, oh my goodness, you know, and I could be dying and have not had, you know, just been an idiot the whole time. So I rushed to the hospital and I didn’t have a heart attack. I just made it so cold that I made my heart work and that supply demand mismatch was happening all night long in my sleep. Bill Gasiamis (13:15)Mm-hmm. Jack Clifford (13:31)And so it got to this, you know, a giant, creeps up, you know, it’s like, can feel it. And then if you push it, you’re like, can really feel it. Well, you know, I woke up out of a dead sleep going from not feeling it when I went to sleep to, to feeling it to the extreme when I woke up. Um, but that’s when they gave me the, uh, the, uh, nuclear stress test with a treadmill test, right in the hospital. And it was, it was really bad. They can’t quantify your blockages with that, but they can tell you that, you know, you’re You’re kind of screwed. And I was like really screwed. Like it was 47, but they said I was one of the worst I’d ever seen. ⁓ yeah. So I had all weekend to think about it, you know, cause I was a Friday, fortunately, and they could, they weren’t going to do the heart catheterization until Monday and the doc, you know, I was signing consent forms for them to do bypass surgery and it was pretty clear that the odds of it getting stented was not really good, but that’s what you hope for. Right. And most people are like, we’ll just get a step. once then in you’re fine. And ⁓ in my case, it wasn’t looking likely. And my mother had had bypass surgery five years before that. And I watched her cognition after the bypass surgery just declined to the point where she’s in memory care now. And she had gone from being this vibrant book author of multiple books and you know, she was a hypnotherapist and she’s helped a lot of people in her life, done a lot of amazing things, but ⁓ she never. she never really came out of the bypass surgery as her whole self and pretty quickly was just completely not herself at all. ⁓ So I wasn’t ready to come back. Now she’s 76. Bill Gasiamis (15:03)How old? How old’s your mom? Yeah. I know with people that are older, ⁓ heart surgery can lead to cognitive decline and there is a link there. There is a number of it’s well researched. It’s a risk. ⁓ not one that you’re probably aware of and that they talk about much, but it definitely is a thing. so, okay. You’re, you’re you go to the hospital. They realize, ⁓ the Jack Clifford (15:15)Mm-hmm. Bill Gasiamis (15:37)charts are not looking good. ⁓ They do the tests. They suggest that what they can offer you is bypass surgery. your, and you’ve got a weekend, think about it and you, and you go home, do they go, do you go home with medication and joining the medications to keep the blood flowing with anything? What do they do? Jack Clifford (15:51)Mm-hmm. Where’d you go? Yeah, such a blessing. No, no, because I was leaving against medical advice so they weren’t going to help me, right? And I actually said to the doc, said, you hey, I’m new here because I just moved a couple of months ago to Florida. And I said, can I come see you? And I didn’t have a cardiologist. I didn’t need one before this. And he says, if you live that long, just walks out. So I was on my own at that point. There was no resources of institutional medicine. I had to go find resources myself. Exploring Alternative Treatments Bill Gasiamis (16:28)Wow. Things are pretty wild in Florida. If you live that long and he walked out. Jack Clifford (16:30)Yeah. Yep. That’s exactly what we said. It’s a very sobering moment for me. Yeah. Bill Gasiamis (16:35)And you walked out. Yeah, and you walked out. Far out, man. So what’s the thinking behind walking out of that? Because I understand ⁓ that there are very few things that, like my situation was different, right? But I’ll give you kind of my thinking behind the, I’m gonna walk out routine. It’s like, there is a part of me that sort of says, I don’t need to subscribe to all that medical stuff, all the nonsense. I wanna try and avoid the medications. I wanna do all of that. Jack Clifford (16:41)Yeah. Yeah. Bill Gasiamis (17:07)That means I’ve got to do some work to get to that point, right? I’ve got to make sure that I’m eating well. I’m sleeping well. ⁓ I’m exercising. ⁓ I’m not overweight. I’m not smoking. I’m not drinking. Like there’s a responsibility that goes with, don’t want to take that medication. Right. And one of the other things is that, ⁓ if it wasn’t for the medical industry, I would not be here recording this, ⁓ podcast. Yeah. So there’s this big thing, which is. Jack Clifford (17:31)Yeah. Double-head sword, right? Yeah. Yeah. Bill Gasiamis (17:37)They’re not fixed. My brain is not getting fixed unless they go in and take out the faulty blood vessel and potentially risk all the complications that, that I got the ones I got, but also the ones I didn’t get, which many people get, which is far worse deficits than what I visible on me. So, ⁓ I’m, you know, I’ve never met anyone in my time who hasn’t Understanding Enhanced External Counter Pulsation (EECP) who has been through the medical ⁓ system, who hasn’t benefited from it in a way that’s sort of sustained their life, supported their life, lengthened their life. Like everyone that I’ve interviewed has always gone through the medical system and has saved them, supported them, helped them, right? And you’re going to, the first place to get help you’re going to is a hospital, right? You ring up and you go, I’ve got to go. Jack Clifford (18:22)Yeah. Bill Gasiamis (18:31)to the hospital because I’m feeling like I’m having heart attack. You get there, they confirm it, and then the place that you go to for help is the place you walk out of. What’s the thinking? Yeah, yeah. You have the angina, the blockages. Yeah, you got all of that. Jack Clifford (18:41)Well, I didn’t have a heart attack. That’s a really important nuance point. you know, I’m sitting in the hospital all weekend. there was nothing at risk in an emergent moment for me. My heart wasn’t, you know, I wasn’t going to lose heart muscle if they didn’t do something. Like my mother’s instance was different. She had a heart attack. She probably needed the bypass surgery. It was really hard on her, obviously, like we talked about, but in my case, I had time, but they didn’t treat it like I had time, right? Bill Gasiamis (18:54)Okay. Okay. Jack Clifford (19:10)They treated it like, we’re gonna go in and take care of this thing for you rather than you have time to explore other options when I knew in fact I did. So it might be that getting bypass surgery is the right move for some folks, but it also might be the right move for you and me. We’ve already discussed that you take care of yourself so you never get in that situation. And yeah. Bill Gasiamis (19:32)Yeah. And this is not a interview about do as I say, this is not that interview, right? What this interview is like one person’s experience and what they did. That’s it. We’re not giving medical advice here. We’re not telling you what decisions to make. We’re not telling you any of that stuff. This has got nothing to do with advising anyone to do anything, but what it has got to do with is what either you discovered Jack Clifford (19:45)Yeah. Right. Bill Gasiamis (19:58)or you knew before and put into action or what you discovered after you left the hospital that weekend. So take us through the next sort of phase of I’m taking responsibility for this and I’m going to take advantage of something that is documented scientifically and proven. Jack Clifford (20:03)Yeah. Okay. Yeah. Mm hmm. Yeah. Yep. Yeah. And you know, like, so I’ll go into that phase, but, but I just want to share this thing because, know, you, you pretty much already told me when you first heard EECP, you like EECP what? Right. And most doctors are EECP what? Basically every patient is EECP what? And it’s, it’s just, it’s really not going to lie. really bothers me because this, this, this therapy is, is so well-documented. It’s, it’s, it’s FDA approved. It’s not controversial. Bill Gasiamis (20:25)Mm-hmm. Jack Clifford (20:43)⁓ it just anyways, okay. So, so, so yeah, so I leave the hospital and the only reason I knew about a EECP was because when my mom had her heart attack, I listened to a podcast by Ben Greenfield. He’s a pretty, you know, pretty high-level guy, right? And that had been, that was like 2015. And I just heard mention of it. was like, it was maybe like two minutes of the, of a 60-minute podcast at most, but I was like noted. So I looked into it from my mom. The closest provider was two hours away and you got to go 35 times and my mom isn’t going to drive. 35 times, you four hours round trip. It wasn’t gonna happen, so we moved on, but I just sort of knew about it. And when I say knew about it, I didn’t know, Bill, like what it actually did or how it worked. I didn’t look into it at that level. just, you know, like assessed the situation. I was like, okay, there’s something out there. That’s it. Okay, yeah. It stands for enhanced external counter pulsation. And you want me to go into a little bit about how it works? Yeah, okay, so. Bill Gasiamis (21:27)Hmm. And what is a ⁓ CP stamp? What does it stand for? Yeah, yeah, let’s do that, yeah. Jack Clifford (21:42)So EECP involves lying on a bed. From the patient experience, you’re lying on a bed. You have ⁓ cuffs wrapped around your calves, your thighs, and your hips. And inside those cuffs, there are little air bladders. Bill Gasiamis (21:55)those cuffs, are they like blood pressure cuffs? The Mechanism of EECP Jack Clifford (21:58)Yeah, like big giant Velcro blood pressure cuffs. Yes. Bill Gasiamis (22:02)Okay, so like they’re much bigger than a regular cuff, which is just over the bicep. Okay. All right. Jack Clifford (22:04)Yes. Yes. Correct. yeah, just that’s the right way to think about it. you you cinch them up, you’re getting really snug in this thing, but it looks like a giant pantsuit, you know? ⁓ And you lie on the bed and then you get a three lead EKG on you. It’s here, here, in here. And then in between heartbeats, the machine… inflates compressed air into those bladders at 1.3 psi to start with, which feels like kind of a gentle massage. And then the pressure can be increased in increments of 0.1 psi all the way up to six, which feels like the exact opposite of a gentle massage. However, if you go slowly, your body accommodates to that pressure and that pressure feels different, both over one session and over multiple sessions, meaning you might not get to six your first session, that’s unlikely, but as you do repeated sessions, you’ll increasingly get closer to six earlier in the treatment and be cumulatively more hours at those higher pressures. And what’s happening is all the blood, not all the blood, a significant amount of blood from your lower body is being pushed up in between heartbeats and it’s causing this phenomenon called sheer stress in your vascular systemically. And wherever there’s pressure differentials in the body, it’s giving a stimulus to grow. It’s saying the pipes are not big enough, you gotta grow. We’re trying to put through more than is gonna fit. The body’s like, wait a second, it’s not big enough. But growing things in the body takes time. And so you need those repeated sessions. Like I mentioned, T.R., before we started recording, it works just like cardiovascular exercise, but at levels humans can’t do on their own. ⁓ And so, yeah. Bill Gasiamis (23:52)That’s important to talk about. so just for a moment, we’ll talk about that. Like it works like cardiovascular exercise. So the idea with cardiovascular exercise is that what, does cardiovascular exercise do that’s similar to EECP? Jack Clifford (24:04)Sure. If you’re out running, when you hit that stride on your feet, you’re doing that same thing, right? You’re ⁓ sending blood up, right? And then your circulation, your heart’s beating twice as fast maybe than it normally is, or substantially more than you’re just sitting here heartbeat is. And that’s because the heart is responding to the environment around it and saying, I gotta get… a lot more blood, a lot more places. So I gotta work a lot harder. you know, is maintenance. So collateral blood flow. have alternate routes that we can use that lie dormant throughout our body. And those collaterals, if they never get used, they honestly, they get weaker and they close off, but they also can be reopened, you know? And then you can grow more of them. And… Bill Gasiamis (24:38)And what’s the result of that? Uh-huh. Okay, so there’s blood vessels that get less ⁓ blood flow because people are sedentary or people aren’t doing the type of exercise that would activate those blood vessels, for example. And then what in theory, not in theory, and then what happens in cardiovascular exercise, the body goes, we need more blood flow, let’s open up. Jack Clifford (25:12)Exactly. Bill Gasiamis (25:26)other areas where normally blood flow wouldn’t be required or doesn’t go. And EECP kind of mimics that mechanism. Jack Clifford (25:27)Yeah. Exactly. Yeah, but not kind of, it’s really important just to note, cause I don’t want, I don’t want any of your listeners thinking, well I’m just going to go run more. Right? I mean, by all means do that safely. You know, the dose always makes the poison with everything, but, but don’t think that you can, you can just go do this. You can do it to a limited degree with exercise, but you’re not going to grow, you know. that I didn’t have that before. And I like it because it shows you like the world of the possibly or it might be a little unsightly, but it’s feeding my brain. EECP has changed my cognition in addition to my heart, you know, my pelvis and my kidneys and my liver. you know, like it’s, it’s optimized blood flow systemically. Um, yeah. Yeah. Bill Gasiamis (26:19)Okay, so let’s go back to the cuff, the cuff that we put on and then what happens. Jack Clifford (26:24)Yeah. Yeah. So, so you just lie on the machine. Typically you do 35 hours on a machine for a course of treatment and one hour a day is a typical, you know, five days a week. That’s just typically you’re going to the doctor. There’s lots of other variations of that, but that’s the typical course. And that’s the most well-researched course. And, ⁓ you know, over time, usually about halfway through those 35 sessions, if you had angina, you’re going to notice a difference, but Personal Transformation Through EECP you know, they use this to treat dementia. It’s a well studied in dementia. There’s a recent study in the US that was profound, a year-long study, a hundred demented patients, roughly a hundred non-demented or a hundred treated patients. Everybody had dementia and a hundred CHAM patients, placebo. The demented patients that got an EECP, they all got better when we know dementia, people get worse in a year, right? They all got better, all of them. And yeah, so that’s like, you know, similar phenomenon erectile dysfunction, similar phenomenon kidney disease, similar phenomenon stroke recovery. So, you know, these are studies. I’m not making it up. It’s just literally like really well documented. It’s not. Bill Gasiamis (27:33)studies that we can get a hold of and put in the show notes, link to the show notes. Jack Clifford (27:36)Yeah, go to to EECPLocator.com and all these studies are there. ⁓ Yeah. So what I did is in the U.S., I, you know, it’s really hard to find. so I couldn’t find it. I had to, I had to call around and like, I could find a few doctors, none of them near me, but a few of them that would had machines, but they would only use them after everyone had failed stints and failed bypass and they had nothing else to offer them, which makes no sense. But that’s how the insurance reimbursements work. Bill Gasiamis (27:41)Okay. Jack Clifford (28:04)That’s the only time they’ll actually pay for it. So that’s what they say it’s good for, but that’s not what it’s good for. That’s just what they can get money for, I guess. but, so I had to drive three hours and take a chance on a doctor and stay in a hotel to get my treatments. And it was really difficult. I mean, I ended up buying one of these machines and got it at my house and I’ve just been using it for the last five years. So, you know, 35 hours was great, but I was pretty bad off. Now I got about 700 hours and, uh, you know, more hours is just greater stimulus to the body to grow vasculature, right? And I mean, I… Bill Gasiamis (28:38)how do you know that you’ve grown? I know there’s this ⁓ feeling or this change that happens in the person. ⁓ Like you said, dementia, ⁓ people who experienced dementia have a better outcome later or a change in the way that they’re brain working, et cetera. can you see the, is there a way to see the difference between the blood vessels and Jack Clifford (29:02)You can’t, you can’t image, could image on a, on a cardiac pet would be like the only imaging or I guess, you know, if I went back and did a stress test again, you would, you would be able to see, cause it’s not quantifying specific arteries. It’s, quantifying the total volume, but I tried that they were, actually wouldn’t let me, they said it’s not safe because you have it at a stent or a bypass. So I went back to the same place that I got it, you know, and I was like, literally they put me through the imaging machine. gave me the dye and then they got Lifestyle Changes and Holistic Health I went to go on the stress test and the same doctor was there and he refused to tell me to go. So I like, wanted to say, hey doc, let’s go for a run. Cause like, you’re not going to keep up with me, but you know, so I, I didn’t bother with that, but I’ve got my own, you know, I did my own little stress, stress test with a treadmill, right? I started, I was getting chest pain. I found out where I can induce angina and I try and say just below it, you know, so I know where it is, right? I was 2.2 miles an hour. That’s not a fast walk. And then after the first 19 sessions where I was staying in the hotel, I got up to 2.7. That’s a really big difference even if it doesn’t sound like a lot. And then I got my machine and I kept going. And then within a couple of months, I was starting to do a running stride. And I could keep that up, no angina. I know where angina would come in. I had time calculations and everything. And then eventually, now I can run. comfortably 6.5 mile an hour pace for quite a while, know, push it up to 14 miles an hour for 30 second sprints and you know, like all kinds of stuff. So, ⁓ Bill Gasiamis (30:38)How long before you break the two hour barrier for the marathon? Like was recently done. Maybe, maybe the more blood vessels, the more blood flow. Maybe you can get there. Jack Clifford (30:42)⁓ I got zero interest in that. Yeah. I think so though, I think those Kenyans should be ⁓ hopping on these EECP machines and they’re I mean, they’re already amazing but. Bill Gasiamis (30:58)Well, you want the Kenyans to just completely own marathon running for the rest of eternity. It’s unbelievable what they did. Right. Like I imagine that there is something else going on there, but I imagine blood flow, oxygenation, more blood vessels. Like it’s got to potentially be a thing. reckon if you do a check between the last guy, me, who’s going to like 50 hours before you get to the other side and those dudes, there would Jack Clifford (31:03)Yeah, yeah, it’ll just be a Kenyan Yeah. ⁓ Bill Gasiamis (31:27)definitely be a difference because they’re exercising all the time, right? Jack Clifford (31:31)Sure, yeah, they’re pushing the collaterals as wide open as, know, whatever, whatever a human can do on their own, they’re doing it to the max to, know, the same phenomenon that EECP is doing for folks lying down. You know, they’re doing it to whatever the max you can without the machine, I would say. Bill Gasiamis (31:48)So this is a bog standard human body task. Like it just does that all the time. I have heard the blood vessels can reroute in the brain when somebody experiences a blockage and then, and it’s not useful at the time of the blockage, obviously, and it causes potential cell death when somebody has a stroke. But then later on. Jack Clifford (32:11)If there’s too much blood, the revascularization, yeah. Bill Gasiamis (32:14)Yeah, so EECP can kind of occur naturally and then it can support as much of the surrounding tissue as possible so that it doesn’t all die off. ⁓ So what you’re talking about is just encouraging EECP ⁓ to happen more than it would normally happen by ⁓ inducing it through this device where people ⁓ get sort of strapped in and then Jack Clifford (32:23)Yeah. Bill Gasiamis (32:43)the machine runs, what does it run like a program? Explain how that works. Jack Clifford (32:47)Literally, it’s just air pressure. got different pumps to pump the calves, the thighs and the hips up. And then it’s really just about the timing, right? It’s got to hit it at the right interval of your heartbeat. So it’s at the right place in diastole where your heart is at rest. that timing is very, crucial. And that’s really… Yeah, it’s not, it’s very old technology. The machine I have was built in 2009. You know, they have new machines that are portable now that I’m working with some of the manufacturers to actually, you know, make these available in the U S because there aren’t any in the U S but they do have portable machines that don’t require a bed. You could get treated on your couch. You could get treated, you know, on your own bed, uh, lying on the floor, I suppose. Um, so, you know, we’ve, we’ve really like technology hasn’t Bill Gasiamis (33:19)Wow. Jack Clifford (33:42)slowed down. just China’s like taking this thing and you know, have a basically every Chinese hospital has several of these machines and they treat patients in the, in the room with us. It’s, part of their standard of care for all kinds of different, different diseases that they’re treating. You know, and it’s adjunctive to just about everything. There’s nothing that you couldn’t do EECP with, right? ⁓ yeah. Bill Gasiamis (34:03)Okay, okay, so. How do you experience your body differently now? And actually, let’s go back actually, how long has it been since you came across this, decided to get the first treatment, implemented yourself ⁓ at home and then how do you feel different now? Jack Clifford (34:08)Oof. Yeah, it’s been five years and four months now. And every since like, this is this is a little hard part to quantify, because there’s been a lot of brain changes to from this, right? So so I don’t even like feel like my 47 year old self who was in the hospital, that feels really like somebody else to me. You know, it’s a version of me, I suppose, but I can’t really relate to that person. Because I like a small example. The Impact of Stress on Health I used to sleep eight to nine hours a night. That was my normal, my whole life. I was generally like the guy that would come in the latest. You could come to work. was the guy that came in the latest. You And now I get up at two 30 most mornings and I’m like, like rare to go with energy. I’m, you know, I’m working out doing resistance training. I’m reading, you know, I wrote a book, I’m writing another book. I’m writing a book on rectal dysfunction as it relates to this phenomenon, because that’s a whole other, you know, case study. and I work a full-time job and I just have an incredible amount of energy basically all the time. My mood is way better. My sense of touch is really different now. I give a lot more hugs because it feels really good. ⁓ My sense of smell and taste and… You know, hearing, you know, I used to like have to go to the bathroom at night sometimes, you know, wake me up to go to the bathroom. Long gone. Bill Gasiamis (35:47)So at the same time though, it sounds like also you might have changed other things as well though, right? So what else have you changed in the meantime? Jack Clifford (35:55)sure. Yeah. Yeah. Yeah. It hasn’t just been EECP. Absolutely. you know, really good supplement routine. ⁓ Pretty extensive, but, you know, managing my lipids, for example, I take a thousand milligrams of niacin twice a day. I’ve been able to bring my triglyceride to HDL ratio to kind of an optimal one-to-one, using fish oil and some other things. ⁓ And, you know, I… I really stay away from carbs for the most part. I like to eat keto, but I like it to be what I call clean keto. So I’m not like pounding keto ice cream or all these things that are, you know, they taste good and yeah, they’re keto, but they got all kinds of oils in them that aren’t really good for your body. ⁓ And, ⁓ you know, I’m big into moving and being active and, you know, having an engaged social life as much as possible as well. I mean, I think that’s a very underrated thing. That’s actually an area I struggle in because I’m working so much, but you even this helps just, you know, getting to know people even online. But, ⁓ Bill Gasiamis (37:04)It sounds like you haven’t re it doesn’t sound like you’ve reinvented the wheel. Like everything that you say is things that people take for granted that if they implemented would improve their life before EECP. We’re talking about EECP today, right? But just those things alone would make a massive difference to somebody’s experience. And that’s kind of the message that I’m trying to kind of get into the Jack Clifford (37:17)Totally agree. I thought it a good Sure. Bill Gasiamis (37:30)⁓ minds and hearts of the stroke survivors who I interview and who listened to the podcast. My book, I’m going to, we’re going to talk about your book in a sec, but I’m going to talk about my book. My book, when I wrote it, I thought I discovered all these things that people, should know about that no one knows about, but it’s not true in here is mindset. ⁓ there’s a chapter about emotional intelligence. There’s a chapter about nutrition. There’s a chapter about sleep. There’s a chapter about community. Jack Clifford (37:32)Yeah. Yeah. No, please. Bill Gasiamis (38:00)⁓ that’s just the five that I can just rattle off the top of my head right now. And you’ve already mentioned that in the last few minutes, that’s exactly the things that you mentioned. And people take it for granted how much that improves your overall health. Right. The Journey of Writing a Book Jack Clifford (38:13)That’s so true. And also what’s wrapped up in the wrapper of all of those things that are threaded together is stress, right? ⁓ If you do all of those things, right, you’re lowering stress. How did I get heart disease at 47 when it happened to my grandfather in his late 60s and my mom in her mid 60s and it happened to me at 47? And we know it didn’t happen at 47. It was years earlier and I realized it at 47. Stress, you know? Like I was the guy that took on a lot. Bill Gasiamis (38:38)Hiding earlier. Jack Clifford (38:44)and had some traumatic things happen in my life and whatever, and I don’t need to go into that. But I always felt like it was all rolling off my back. Like, you know, I’m fine. know, like I didn’t, and there are reasons why I felt that way. ⁓ However, at the end of the day, I know that I wasn’t processing. There was so much I did not process. And I didn’t learn how to like have really good boundaries and that, you know, begot more stress because of those lack of boundaries and, but stress, right? You know, like, but if you have good good social life and healthy people in your lives, that takes stress off. Eating the right food takes oxidative stress off your body. You could go on and on, but I think stress is gonna kill you before anything else. Bill Gasiamis (39:17)you Yeah. I love that you said that. I love what I love that. That was the answer that you gave when I said, what else did you do? Because it’s not just, you know, it’s like, I’m going to eat well, but smoke, you know, I’m going to eat well, but drink excessive amounts of alcohol. Like, no, it doesn’t work. You know, you can’t do that. Yeah. can’t do. Yeah. Small. Jack Clifford (39:42)No, you gotta do it all in concert. It’s the layers, right? Yeah. Bill Gasiamis (39:49)numbers, know, the percentages they add up, you know, 1 % here, 1 % there all adds up and you get a result at the end of it. Okay. So, so you’re you’ve gone, I’m going to see if I can grow new blood vessels to support my heart. And what you’re found between the time that you went to hospital around five years ago to now is that the angina has Jack Clifford (39:55)Yeah. Mm-hmm. Bill Gasiamis (40:17)⁓ improved, they’ve gone away. The heart has improved, I beg your pardon, the blood flow. And have you had a medical examination since then to do other comparison? Jack Clifford (40:28)Yeah, I have. Yeah, I’ve got a cardiologist. I haven’t seen him and I’ve talked to him the other day because I talked about the book, but I haven’t gone to see him because he’s a plane flight away. But I’ve been worked up for the crowded intermediate thickness. You might be familiar with that as it relates to stroke. okay, well, they just measure your crowded arteries and look at the placking in your crowded arteries as a proxy for your systemic plaque burden. And flow mediated deletation, is they totally occlude the… the arm with a blood pressure cuff and then see how quickly you can refill it after, you know, like, it’s like five minutes of this, your hand is completely numb. And those all, you know, workups were good and that was after a couple of years of treatment. You know, I tried to have that stress test, like I mentioned, but you know, now I just see my primary care, you know, he’s a good guy and he runs on my lipid panels and, ⁓ you know, so I’m definitely monitored, but. What I haven’t done is gotten re-imaged because I don’t want to put extra dye in my system. Sure, somebody wants the images because they don’t believe me, but I’m not trying to sell anybody anything here. I’m just trying to spread the word on something. If somebody doubts my honesty, they can, it’s fine. Bill Gasiamis (41:38)I know what you mean, Jack. I know what you mean. I and I asked you because yeah, I would love to see that before and after. would love to see the blood flow. What’s happening, watch change. would be amazing. story to tell, but I also went out of my way if I could to avoid having more dyes and all that kind of stuff injected into my body. I totally get it. It’s okay. Yeah. ⁓ Jack Clifford (41:49)Yeah. Yeah. Yeah. Bill Gasiamis (42:01)Okay. So you wrote a book about it. Like, what was the idea behind the book? What were you thinking? Show us the one that you got there with the old book cover. And then I’ll include the new book cover in this image as we chat. Jack Clifford (42:06)yeah. Yeah. Yeah. Yeah. Thanks. Yeah. So I started writing this book, in, know, ⁓ November timeframe, ⁓ after I mentioned to you, so my, my friend came down, ⁓ and stayed with me for 13 days and he had had some stroke damage five years before that was, you know, his whole right side, he just had like numbness and then pain. And then, you know, it this weird cascade of symptoms so bad, you know, sometimes he couldn’t sleep from it. And so All the time he took off work he could he came and he used the machine three times a day and then he left pain free and like nothing else had worked and then this worked and I didn’t per se expect that I but I was like, you I know it does stuff. It’s helpful. But anyways, when I saw that, you know, I really started digging even more because before that I was like, well, Jesus is amazing. But maybe it’s just me, you know, and and anyways, so, ⁓ so then I, you know, I just started writing the book one day and The Role of EECP in Heart Health You know, my mom was a book author and I always wanted to write a book. didn’t really have anything particular to write about and all of sudden I do. So I’m like, you know, let’s see what happens. And, uh, and you dig into the research more and more, and you’re just like, increasingly frustrated by how everyone has known about this. And yet, you know, they don’t promote it. They don’t talk about it because it’s inconvenient. You know, and I’m going to get a little, try not to get like soapboxy here, but Bill Gasiamis (43:36)Do it, do it, go for it man. Jack Clifford (43:37)Okay, okay, because, you know, cardiologists will say it, some of them, the ones that are honest, they’ll be like, like mine. He says, I was making obscene amounts of money, giving people bypass surgeries instance. And then I was given the same people bypass surgeries instance, a couple years later. And, you know, and then he stumbled upon some answers and EECP is one of them that helps his patients stay well. And, you know, he makes a lot less money. because of it, because he doesn’t go in and do these interventional approaches. And, you know, EECP, the most you could pay somebody is like $100 an hour, and you’re going to tie up a patient room for 35 hours with a tech, it doesn’t make any sense. I go pop a stint and you make 10 grand in two hours and never see you again. You know, like it just, I get it from, you know, I want to own a portion of Ferrari and have a lake house and a winter house, but You know, like, I don’t know how you live with yourself. You said go for it, man. I’m going to go for it. you know, and my son’s about to graduate. Okay. Yeah. Okay. Fair enough. I’m good with it. Yeah. Yeah. Bill Gasiamis (44:38)But come on, come on, Jack. Yeah, you go for it. I’m going to push back. I’m going to push back as well. You go for it. I’ll push back. There’s yeah. Which is cool. Right? That’s what I want. I want to have a conversation and I don’t want to control the narrative, but the guy that goes in needs a stint today has a blockage. Like that’s life saving. That does work. What I am afraid of that happens sometimes when people go in and they’ve got a blockage and then they get ⁓ even even a stroke blockage. Right. in carotid or a vertebral artery. What happens is sometimes people go in and they get told you need a stent. Fair enough. You’re about to have a heart attack. You’re about to have a major stroke. If we don’t put one in, you’ll have a, that’s necessary. The challenge is, that that person sometimes doesn’t learn the lesson of what got them into the situation where they need a stent. Jack Clifford (45:22)Good. Exactly. sure. Yeah, by all means. Like emergency medicine is great. And we’ll put that in the emergency medicine category of cardiology, right? Why aren’t they offering you, why aren’t they saying, Hey, you’re at risk for a whole lot of other things just by this happening. Why don’t you come 35 times to this EECP machine and you know, like, or why don’t we have centers Bill Gasiamis (45:36)Yeah. Yes, and then later… Jack Clifford (45:55)all over. I found exactly one place in Australia so far that I’m not focusing on Australia right now. I do plan to take EECP Locator International, but right now the access points in the US are abysmal. 70, 80 % of the people in the United States could not get to a center. There’s no access point that’s at all realistic for them to get to. And yet these machines are not that expensive. They’re the price of a Decent not that great car. ⁓ Bill Gasiamis (46:24)we’re starting to see them in, I don’t know, health spas or something like that, where people will go, they’ll get yoga, they’ll get this, they’ll get that, they’ll get infusions perhaps and all sorts of other things. And there’ll be a machine or there’ll be a suit that people can put on and they can go through one hour. Jack Clifford (46:29)Yeah, that’s good. That’s great. Yeah, although I do want to say that the Normatech, like the compression boots that they have and some of those things, when they don’t use the pressures that EECP uses up to 6 PSI and they’re not sinking it in between heartbeats, it’s helpful, but we’re not talking about things that can do the same thing in the body. It’s on the right path and I’m not digging it as being worthless because it’s not, but it’s just not the right thing. Bill Gasiamis (46:47)Yes. Yeah. Yeah. Yeah, that’s kind of what we’re seeing. And to go back to your point is because the medical profession does medical profession stuff. this is not, it’s not that it’s not medically kind of aligned. It definitely is. But when you’re told that the way you solve a problem is through putting a stent in and then never talking to that patient again, to tell them how to avoid to get a stent in that’s Jack Clifford (47:31)Yeah, that’s your job. Bill Gasiamis (47:34)what they do, like they’ve been trained to do that forever. And that’s what they do. And that works and it saves the life. But what it doesn’t do, which I also have a challenge with this, it doesn’t teach the lesson. What it reinforces is that if I have something wrong with me and I go to a doctor, they’ll fix it. So next time it goes wrong, I’ll just go to the doctor and they’ll fix it again. And I didn’t have to change my life. Like this even bloody advertisements that do that. They Jack Clifford (47:51)just I’ll go and he’ll fix it. Yeah. Yes. Yes. Bill Gasiamis (48:03)They hijack that part of the person’s brain and they say, you know, have you got reflux, heartburn, that kind of stuff? Don’t let reflux and heartburn get in the way of eating the foods that you love. Just take a tablet. You know, that’s the same kind of thing, right? And that’s why the medical profession doesn’t do that because they’re not trained to do anything other than sell their thing. And their thing is what they went to work, to school for. Raising Awareness for EECP Therapy Jack Clifford (48:17)Yes. Bill Gasiamis (48:30)20 years to be able to administer. But every so often you come across an amazing doctor, surgeon, et cetera, who says, I can’t do anything more for you, but maybe somebody else can. Those guys are better than the doctor who says, we can’t do anything else for you and then send you off their way. That next sentence, but maybe somebody else can, I don’t know who they are. That is. Jack Clifford (48:43)Mm-hmm. Bill Gasiamis (48:57)I think a great thing to say this is where I think EACP kind of fits in that now that I’m here and things are not good. Jack Clifford (49:05)I totally agree. I totally agree. And yeah. And you, so you, you mentioned like the wellness spas and whatnot. And here’s the thing in 2015. So, you know, somewhat recently the FDA approved EECP for a brand new indication, general circulation, right? In healthy people. Like it’s right on the FDA indication. And also in one case in increase in VO2 max, but rough, that’s roughly saying the same thing. ⁓ yeah. Bill Gasiamis (49:32)for healthy people, was that part of it? Jack Clifford (49:35)Yeah, it said unhealthy patients and healthy people didn’t call patients. So, so, ⁓ but, but, know, the litmus test for that is, is your doctor say you’re healthy enough to undergo circulation enhancement? If the answer is yes, you know, it doesn’t matter if you got all that other stuff or not, you know, we’re just not treating you for it. We’re not saying ECPs is fix for this, your erectile dysfunction. It might help it. You know, what’s not saying it’s, it’s the fix for your stroke, but it might really help your stroke, recovery, but. Bill Gasiamis (49:47)which Jack Clifford (50:03)Anyhow, so like you can, you know, I don’t know about in Australia, but in the United States, you could get an EECP machine and create a viable business model off of helping people as soon as people actually know about it and what it does, right? I’m trying to solve the access issue in the United States by aggregating demand, right, as one of the solutions. So I have a website, eecplocator.com. And if people… ⁓ tell me that they like EECP to be available in their area, when I get like five to 10 patients in one area, we’re gonna find a way to get it to them. ⁓ The how is, you there’s a bunch of different possible ways we can get EECP to them, but at the end of the day, you know, like people need this treatment. They really, really do. Bill Gasiamis (50:50)Yeah. We’re not talking about anything ⁓ out there. Like this is not an out there thing. This is definitely common. Now I, I don’t know how I haven’t come across it. I’ve all these years after all these years now I’ve just because of our conversation right now, I just did a Google search and I typed in EECP machine Australia. And the first thing that came up was an Australian government department of health, disability and aging. Jack Clifford (50:57)No, it’s that. Bill Gasiamis (51:20)document from the Therapeutic Goods Administration, which talks about a mid-trade Australia EECP system model, external counter pulsation system stationary. So it seems like they have a… Jack Clifford (51:36)Like they’ve approved it, sounds like they have some approved devices. Yeah. Bill Gasiamis (51:38)Something like they’re at least looking at it. Let me see what that says. The inclusion of the kind of device in the AI community is subject to compliance with conditions placed in post. Yeah, it sounds like it’s been through some regulated body in 2021. Jack Clifford (51:52)Yeah. Mm-hmm. Yep. There you go. Bill Gasiamis (51:57)This device is intended to provide external counter pulsation therapy and is indicated for use in the treatment of stable angina. Jack Clifford (52:06)Mm-hmm. Bill Gasiamis (52:08)pectoris and congestive heart failure. There you go, my friend. Jack Clifford (52:10)Yeah, it works great for people with art failure. It really does. Bill Gasiamis (52:14)Dude, father-in-law had heart failure. He passed away from heart failure just a few, about a year and a half ago. ⁓ Now, I don’t know, I’m not saying anything, but we’ve never heard of this before. Today’s my first time where I’m really going to deep dive about this thing with you. ⁓ So what are the challenges that you face? what are the, what is it? ⁓ The barriers that you face? Jack Clifford (52:20)Yeah. Bill Gasiamis (52:44)when you’re speaking to people about this or how people finding out about it, how do you help people like Jack Clifford (52:50)It’s just an awareness piece. It’s an EECP what? And then, you you get in with some physicians and then you got to duke it out a little bit. Not with all of them. There’s plenty of physicians, you know, I’ve talked to the physicians that have machines and are doing the right thing for society and still making plenty of money. ⁓ They’ll just tell you, you know, I’ve talked to some cardiologists and just they kno

As part of the US HUPO sponsored "All the Parts", Ben and Ben sat down to talk with Dr. Sasha Singh, Harvard Medical School, and Dr. Sarah Parker, Cedars-Sinai (also featured in Ep 15).keywords: hEDS; POTS; valves; foamy macrophages; atherosclerosis; aneurysm

Daily Dad Jokes (04 Mar 2026) Christmas Joke Button - 101 eye rolling dad jokes for the festive season! Amazon. The perfect gift for Kris Kringle, Secret Santa and of course for dad! Click here here to view! The official Daily Dad Jokes Podcast electronic button now available on Amazon. The perfect gift for dad! Click here here to view! Email Newsletter: Looking for more dad joke humor to share? Then subscribe to our new weekly email newsletter. It's our weekly round-up of the best dad jokes, memes, and humor for you to enjoy. Spread the laughs, and groans, and sign up today! Click here to subscribe! Listen to the Daily Dad Jokes podcast here: https://dailydadjokespodcast.com/ or search "Daily Dad Jokes" in your podcast app. Jokes sourced and curated from reddit.com/r/dadjokes. Joke credits: No-Sea-7094, IStillListenToRadio, west_head_, Slowloris81, AndrewMacSydney, Necrotat2, AnimatorNr1, Necrotat2, Corvin53005, _tony_lewis, santillinight, berkleysquare, berkleysquare, , Legal-Statistician2, rzarou, Legal-Statistician2, bobismymother, Legal-Statistician2, StewPidpizzachit, Healthy_Ladder_6198 Subscribe to this podcast via: iHeartMedia Spotify iTunes Google Podcasts YouTube Channel Social media: Instagram Facebook Twitter TikTok Discord Interested in advertising or sponsoring our show? Contact us at mediasales@klassicstudios.com Produced by Klassic Studios using AutoGen Podcast technology (http://klassicstudios.com/autogen-podcasts/) Learn more about your ad choices. Visit megaphone.fm/adchoices

Daily Dad Jokes (04 Mar 2026) Christmas Joke Button - 101 eye rolling dad jokes for the festive season! Amazon. The perfect gift for Kris Kringle, Secret Santa and of course for dad! Click here here to view! The official Daily Dad Jokes Podcast electronic button now available on Amazon. The perfect gift for dad! Click here here to view! Email Newsletter: Looking for more dad joke humor to share? Then subscribe to our new weekly email newsletter. It's our weekly round-up of the best dad jokes, memes, and humor for you to enjoy. Spread the laughs, and groans, and sign up today! Click here to subscribe! Listen to the Daily Dad Jokes podcast here: https://dailydadjokespodcast.com/ or search "Daily Dad Jokes" in your podcast app. Jokes sourced and curated from reddit.com/r/dadjokes. Joke credits: No-Sea-7094, IStillListenToRadio, west_head_, Slowloris81, AndrewMacSydney, Necrotat2, AnimatorNr1, Necrotat2, Corvin53005, _tony_lewis, santillinight, berkleysquare, berkleysquare, , Legal-Statistician2, rzarou, Legal-Statistician2, bobismymother, Legal-Statistician2, StewPidpizzachit, Healthy_Ladder_6198 Subscribe to this podcast via: iHeartMedia Spotify iTunes Google Podcasts YouTube Channel Social media: Instagram Facebook Twitter TikTok Discord Interested in advertising or sponsoring our show? Contact us at mediasales@klassicstudios.com Produced by Klassic Studios using AutoGen Podcast technology (http://klassicstudios.com/autogen-podcasts/) Learn more about your ad choices. Visit megaphone.fm/adchoices

You may imagine your vasculature as a vast and silent network of tubes, dutifully carrying blood, oxygen, and nutrients to every organ and tissue. These vessels seem purely mechanical, like plumbing hidden behind walls, doing their job quietly and invisibly. Yet modern biology has revealed a far richer and more surprising reality. Blood vessels are lined with living, sensing, responding cells called endothelial cells, and these cells are anything but passive. They listen to chemical signals, respond to stress, regulate traffic, and communicate constantly with the immune system.

Episode 343 The task of growing human brains in a lab has taken a step forward. Scientists have been creating brain organoids since 2013, but have now grown blood vessels in them for the first time. These mini brains resemble the developing cortex - the area of the brain that thinks, feels and stores memories. These advancements will help us learn more about the brain and conditions like dementia. But what if we go too far and they become conscious? Geoengineering is being talked about more and more as countries fail to hit emissions targets. Without reductions we are on course to hit 4.5°C of warming by 2100, so new solutions are needed. But will artificially cooling the climate really help, or do even more damage? One popular method is solar radiation management - but that would require at least 100 aircraft working for hundreds of years. And new research shows that while it could work, the moment we stop doing temperatures would rebound rapidly. So is it worth even trying? An incredible trove of ancient fossils have been discovered in a quarry in China, dating from 512 million years ago, just after Earth's first mass extinction event. More than 8000 fossils have been analysed and nearly 60 per cent of the species are new to science. This group of arthropods, molluscs and brachiopods contain some very weird and wonderful creatures - including one which looks remarkably like a penis with long branching tentacles growing out of the end. Hosted by Rowan Hooper and Penny Sarchet, with guests Carissa Wong, Alec Luhn and Sam Wong. To read more about these stories, visit https://www.newscientist.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Guests:Dr Mihai Lomora, Scientist with CÚRAM, the Research Ireland Centre for Medical Devices based at the University of GalwayDr Jessamyn Fairfield from the School of Natural Sciences at the University of GalwayDr Fergus McAuliffe, Head of Research Engagement and Impact at Trinity College Dublin

Surprising council flows from the Great Spirit of the Blood Vessel in this episode of Gaia Translate. Want access to the transcript and show notes for future episodes? Visit our website at www.gaiatranslate.com Please rate, review and share the Gaia Translate podcast with your friends and colleagues so that more of us are able to receive this timely communication from the greater family of life we are all a part of.

More evidence that unfossilized tissue in dinosaur fossils is indeed dinosaur protein.  Using a new laser technique, hemoglobin has been identified in dinosaur soft tissue.

Chronic inflammation quietly damages nerves, joints, and blood vessels, leading to long-term pain and illness, but natural anti-inflammatory drinks can provide gentle relief without harsh drug side effects Tart cherry juice, rich in anthocyanins and melatonin, has been clinically shown to reduce nerve pain, lower inflammation, and improve sleep, offering a safe, research-backed alternative Green and white teas are antioxidant powerhouses with catechins that protect nerve cells, calm inflammation, support circulation, and even provide antimicrobial benefits for long-term nerve and immune health Ginger tea and golden milk harness ancient healing compounds like gingerol, shogaol, and curcumin to ease inflammation, improve circulation, reduce oxidative stress, and promote tissue healing Fresh juices from carrots and celery hydrate the body, deliver antioxidants, and support nerve protection

BUFFALO, NY — October 14, 2025 — A new #research paper was #published in Volume 17, Issue 9 of Aging-US on August 30, 2025, titled, “Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity.” In this study, led by Daniel R. Machin from the University of New Mexico School of Medicine and the University of Utah, researchers found that protecting a fragile layer lining blood vessels, known as the glycocalyx, can prevent muscle deterioration and help maintain physical performance during aging. They also discovered that a supplement containing high-molecular-weight hyaluronan (HMW-HA), a key component of the glycocalyx, enabled older mice to preserve muscle mass and exercise capacity. These findings suggest that targeting the glycocalyx may offer a new approach to reduce frailty and support mobility in older adults. As this layer degrades with age, it contributes to cardiovascular and muscular decline by impairing blood flow and vascular health. The study examined how preserving the glycocalyx using a therapy called Endocalyx™ affects physical function in aging mice. Researchers first studied genetically modified mice lacking Has2, the enzyme responsible for producing HMW-HA. These mice had a thinner glycocalyx, reduced exercise performance, and lower mitochondrial function in their muscles, even though muscle size remained normal. This indicated that glycocalyx damage alone can directly impair physical performance. The team then gave older mice a diet containing Endocalyx™ for 10 weeks. Compared to untreated controls, these mice maintained muscle mass and performed better on treadmill tests. Notably, the treated mice did not show the typical age-related decline in muscle strength and endurance. While the supplement did not fully restore youthful performance, it significantly slowed physical deterioration, suggesting a protective benefit. In contrast, untreated older mice lost both body mass and muscle volume during the same period. “Taken together, these findings provide direct evidence of a role for HMW-HA in the modulation of exercise capacity.” This research builds on prior evidence that the glycocalyx is essential for healthy blood vessel function. Since muscle health depends on proper blood flow and oxygen delivery, restoring the glycocalyx may help maintain strength and mobility with age. While more research is needed to confirm these results in humans, the findings point to a potential therapeutic approach to promote healthier aging. DOI - https://doi.org/10.18632/aging.206313 Corresponding author - Daniel R. Machin — dmachin@salud.unm.edu Abstract video - https://www.youtube.com/watch?v=S7HjCeXT8fU Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206313 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, glycocalyx, hyaluronan To learn more about the journal, please visit our website at https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Nutritionist Leyla Muedin discusses the critical health impacts of visceral fat, which is the hidden fat around the organs, and its role in accelerating heart aging. Drawing from recent research conducted by the Medical Research Council and published in the European Heart Journal, she explains how visceral fat differs from subcutaneous fat and its association with inflammation, heart diseases, and premature aging. The episode also highlights the importance of exercise, diet, particularly low-carb intake, and hormone replacement therapy in managing visceral fat and reducing health risks. Leyla also shares practical dietary advice and underscores the significance of focusing on fat distribution over total body weight for better health outcomes.

[13x1] We begin Season XIII with the BBC-Netflix three-part miniseries of Dracula, from the creators of Sherlock, which finds the Count (Claes Bang) being pursued across Europe in a post-modern twist on Bram Stoker's novel and the gothic Hammer traditions... And making his return to the show is author and podcaster Tony Black... Hosts: Hugh McStay & Dan Owen Guest: Tony Black Editor: Hugh McStay "I'm undead not unreasonable." -- Dracula Jump ahead to a particular episode: (00:01:55) "The Rules of the Beast" (00:34:02) "Blood Vessel" (00:57:13) "The Dark Compass" Enjoying what you hear? Please subscribe, leave a rating, or write a review to help us keep bringing you great content! You can also show your support by leaving a donation at ⁠Ko-fi ⁠⁠. Stay connected and follow our social media ⁠⁠here⁠⁠. A proud part of the ⁠Film Stories⁠⁠ podcast network. Theme music by ⁠Nela Ruiz⁠ • Episode art by ⁠Dan Owen⁠. Podcast art by ⁠Keshav⁠. Learn more about your ad choices. Visit megaphone.fm/adchoices

Vidcast:  https://www.instagram.com/p/DN038nZ3AWE/Even a mild case of CoVid will age your vital arteries 5 years.  This from a study by French cardiologists recently published in the European Heart Journal. The cardiovascular researchers studied data from 2090 individuals in 16 countries from late 2020 through early 2022.  Arterial aging was estimated by measuring the degree of vessel stiffness using pulse wave propagation measurements.  The negative effects of a CoVid infection were more significant in women and in those reporting lingering, long CoVid symptoms.On the positive side, those vaccinated against CoVid suffered less arterial stiffening following a CoVid infection.  Add this to the other benefits of vaccination including a less severe infection with a significantly lower risk of death.It's important to note that vascular aging, when “natural” or prodded along by CoVid, can be reduced by exercise, blood pressure control, healthy eating, and cholesterol-lowering medications.  Just to repeat, If unchecked, this blood vessel aging will increase your risks of a heart attack and stroke.https://medicalxpress.com/news/2025-08-covid-infection-ages-blood-vessels.htmlhttps://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehaf430/8236450?login=false#CoVid #coronary #vessel #stiffening #heartattack #stroke

pWotD Episode 3033: Brent Hinds Welcome to popular Wiki of the Day, spotlighting Wikipedia's most visited pages, giving you a peek into what the world is curious about today.With 213,277 views on Thursday, 21 August 2025 our article of the day is Brent Hinds.William Brent Hinds (January 16, 1974 – August 20, 2025) was an American musician best known as the lead guitarist of the Atlanta heavy metal band Mastodon, in which he shared guitar duties with Bill Kelliher and vocal duties with Troy Sanders and Brann Dailor.Hinds was also lead guitarist/singer for the surfabilly band Fiend Without a Face, and was involved in other projects, including classic rock bands The Blood Vessels, West End Motel, Four Hour Fogger, The Last of the Blue Eyed Devils, Giraffe Tongue Orchestra, and Legend of the Seagullmen.This recording reflects the Wikipedia text as of 01:25 UTC on Friday, 22 August 2025.For the full current version of the article, see Brent Hinds on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Mastodon at @wikioftheday@masto.ai.Also check out Curmudgeon's Corner, a current events podcast.Until next time, I'm standard Aditi.

Jerit Leo Mitchell is a Physics PhD Candidate at the University of Regina. Learn more about your ad choices. Visit megaphone.fm/adchoices

The Daily Quiz - Science and Nature Today's Questions: Question 1: In medical terms, what is the name of a condition in which a blood vessel gets blocked by an air bubble moving through the bloodstream? Question 2: An animal is a fish if it has what? Question 3: What is Allergology the study of? Question 4: In computer networking, what does DNS stand for? Question 5: Which of these medical terms comes from an Ancient Greek word meaning "without sensation"? Question 6: What name is given to animals which only eat plants? Question 7: Excluding humans, what is the longest living land mammal? Question 8: A male chicken is known as what? This podcast is produced by Klassic Studios Learn more about your ad choices. Visit megaphone.fm/adchoices

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Will: Dr. Cabral, I am trying to get information on a healthy all natural substitute for alcohol. I have stopped drinking since I've been actively using your products and enjoying my new lifestyle. Still sometimes I have the need/urge to relax in the evenings or while out with friends and family. What can you tell me about this product? https://www.calmingco.com/?srsltid=AfmBOor6Jl5JF5dSf0ia1k1GSuWSMLPznoChs_nnnV8LQr88V4C7yR6u                              Christin: Can you speak to some ways to support a child (11 yrs) with type 1 diabetes? My daughter was diagnosed 3 years ago with autoimmune T1D. I've looked into stem cell therapy as one option to restore pancreatic function and several of the protocols include an IV detox prior to the therapy. Some of them can be done with children and others cannot. I would love to help her body every way possible, but it seems options are often limited for children. What can I do to help her body function optimally?                                                                                                                                                     Patrick: Hey dr I just listened to your podcast on kidney stones. I believe you mentioned before that you could do a shot of olive oil and lemon but you didnt mention it this time is it still something you recommend. Thanks                                    Andy: Hi dr c, we love all you do. Post jab in 2021, and almost immediately, I developed burning all over my body which has now culminated in a diagnosis of small fiber neuropathy and pots. Perhaps the worst symptom has been my intolerance to exercise in the form of rapid heart rate and headaches post exercise. I have had done all types of functional medical tests including stool tests, organic acid tests, mould tests and listened to all your pots podcasts. Nothing major ever shows up. I did you mould protocol which helped some underlying gut issues. I have qualified for IVIG treatment. Do you suggest running the big 5 or proceeding with the IVIG and do you have any views on long term effects of IVIG. I am 33, healthy and was a long distance runner before all this. Love from down under.          Kim: Hi Dr. Cabral, My 13 year old son has HSP which is inflammation of the blood vessels. That's what I gather anyway. We found out he had it after coming down with a virus and/or food poisoning. He had red dots all over the lower legs which turns out was due to the capillaries breaking. He has high amounts of protein in his urine. We are going to meet with a specialist for it but I was wondering if you could help me figure out what supplements to have him take? They're probably going to want to put him on a small dose of blood pressure medication to relieve some stress on his blood vessels but he doesn't have high blood pressure. I know there are things I can do to help his body but I just don't know what that is. Any advice you have for me to help my child, I would really appreciate it!                  Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3438 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Most cardiologists wait until you're having a heart attack to intervene. Dr. Michael Twyman, a board-certified cardiologist and founder of Apollo Cardiology, is flipping that script entirely. In this groundbreaking episode, Dr. Twyman reveals why conventional cardiology is missing the real root causes of heart disease and how quantum biology, mitochondrial health, and circadian rhythms are the future of cardiovascular medicine. Dr. G and Dr. Twyman dive deep into: – Why nitric oxide is your heart's most critical molecule (and how to optimize it naturally) – The glycocalyx: your blood vessel's protective coating that most doctors ignore – How your oral microbiome directly impacts your cardiovascular health – Why grounding and sunlight are essential for heart health – The cutting-edge labs your cardiologist probably isn't ordering – How to spot early signs of heart disease decades before symptoms appear. This isn't about cholesterol and cardio. This is about understanding your heart as an electrical, quantum system that thrives on light, movement, and proper fuel. Dr. Twyman shares practical protocols for optimizing mitochondrial function, supporting endothelial health, and preventing cardiovascular disease at the cellular level. If you want to live longer and stronger, this episode will completely reframe how you think about heart health. #hearthealth #cardiology #mitochondria Dr. Michael Twyman Website: drtwyman.com Instagram: @dr.twyman Timestamps:  00:00 - Heart Health Beyond Cholesterol & Cardio 02:06 - Proactive vs Reactive Cardiology 05:15 - Lipoproteins: The Real Heart Disease Markers 12:17 - Nitric Oxide: Your Heart's Master Molecule 21:04 - Mitochondrial Health & Heart Function 25:25 - Glycocalyx: Your Blood Vessel's Protective Coating 29:14 - Sleep, Stress & Cardiovascular Health 36:27 - Travel Protocols for Heart Health 39:16 - Best Foods for Heart & Blood Vessels 43:33 - Carnivore Diet & Heart Health Risks 47:24 - Final Heart Health Recommendations Hosted by Doctor Christian Gonzalez N.D. Follow Doctor G on Instagram @doctor.gonzalez https://www.instagram.com/doctor.gonzalez/ Sign up for our newsletter! https://drchristiangonzalez.com/newsletter/

We'd love to hear from you! Please send us a Text Message!So much of life I take for grantedI wake each day to face the same routineThe colors often runIn shades of monotone and greyAnd the days melt togetherIn a frivolous clichéBut occasionally, now and thenOnce or twice when the moon is blueI'll be walking across a roomAnd a thought will comeFrom out of nowhereSo stunningAs to make meStop in my tracksTo consider the infiniteThe mysteries of lifeTheater of the Imagination is brought to you by Watchfire Music Updated Watchfire Music Commercial To access all of the episodes in our podcast, please subscribe to Watchfire Music's Theater Of The Imagination Subscription Series. Unlock all of the episodes and experience so much more! Learn More here: https://bit.ly/theater-of-the-imagination-info Or, if you're ready to subscribe, subscribe here: https://bit.ly/subscribe-to-theater-of-the-imagination We'd love to hear from you! Please send us a Text Message!

In this episode of the Binge-Watchers Podcast, Johnny Spoiler reflects on a heartfelt Instagram post about chasing creative dreams while juggling the grind, and it gets personal. From Clueless revivals to space tourism as an expensive meme, we dish on the latest Home Video Headlines, including wild rumors like Rotta the Hutt as a gladiator in Star Wars.Dive deep into the WWII vampire horror flick Blood Vessel with behind-the-scenes trivia, killer vampire designs, and why the soldiers' struggles keep you hooked. Plus, themed movie-watching tips, unexpected burrito fan encounters, and some spicy Staff Picks to elevate your Thursday night lineup.

Tuesday, March 18 -  Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics affecting our health. First up, Doug and Dr. Ken discusses new research in which Dr. Ken has been cited with Enhanced External Counterpulsation  (EECP), a noninvasive way to put new blood vessels into the heart — a procedure Doug, himself, has received. Other news includes the day of the week for which you don't want to schedule your surgery and why it's Friday, a warning for anyone thinking of getting tattoos, breaking down the details on Gene Hackman's autopsy, and the importance of sleep in the first weeks after a concussion and how it helps recovery. Next up, how a correlation between sleep and blood pressure in teens, and  why strength training can help insomnia sufferers. Doug is also joined by Elizabeth Miller to discuss the favorite weight loss capsules, Calotren, and why taking the capsules before you go to bed can have a positive impact on sleep. It's not just for healthy and sustainable weight loss. The best part, listeners of Doug Stephan's Good Day Networks radio programs and podcasts are privy to a special deal: visit TopLoss.com where you can build your own package, and use the code “DOUG” at checkout for extra savings.Website: GoodDayHealthShow.com Social Media: @GoodDayNetworks

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/

February is American Heart Month, and in light of that, we're bringing back an episode about a group here at Stanford Engineering that's developing 3D printing methods for human tissues and organs, a process known as bioprinting. Motivated in part by the critical need for heart transplants, Mark Skylar-Scott and his team are specifically working to bioprint tissues of the human heart. It may sound like science fiction, but it's actually just another example of the groundbreaking research we do here. We hope you'll take another listen and be inspired by the possibilities.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Mark A. Skylar-ScottMark's Lab: The Skylar-Scott Lab | Stanford MedicineConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest, Mark Skylar-Scott, a professor of bioengineering at Stanford University.(00:02:06) What is Bioprinting?The role of cells and biopolymers in printing functional biological structures.(00:03:31) Bioprinting a HeartThe potential of printing organs on demand, especially heart tissue.(00:04:38) Obtaining Cells for BioprintingUsing stem cells derived from the patient's own cells to create heart tissue.(00:06:29) Creating Multiple Cell Types for the HeartThe challenge of printing eleven different heart cell types with precision.(00:08:50) The Scaffold for 3D PrintingThe support material used in 3D printing and how it's later removed.(00:10:10) Cell Migration and Organ FormationHow cells organize themselves to form functional heart tissue.(00:12:08) Growing a Full-Sized HeartWhether they're printing full-sized hearts or starting with smaller organs.(00:13:34) Avoiding Overgrowth RisksThe role of bioreactors in shaping the early stages of the organ.(00:14:57) Scaling Up Cell ProductionThe need to generate massive numbers of cells for experimentation.(00:18:32) The Challenge of VascularizationCreating a blood vessel network to supply oxygen and nutrients.(00:22:35) Ethical Considerations in BioprintingConsent, stem cell sourcing, and the broader ethical landscape.(00:26:04) The Timeline for Bioprinted OrgansThe long timeline for bioprinted organs to reach clinical use.(00:27:24) The State of the Field & CollaborationThe collaborative, competitive biofabrication field and its rapid progress.(00:28:20) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Doctors fleeing Medicare—leaving patients stranded; CEO murder heightens scrutiny of United Healthcare's Medicare Advantage coding shenanigans; Can blood pressure spikes cause strokes? Does a calcium score of 20 call for a statin Rx? Treatments for postural orthostatic tachycardia syndrome (POTS); New “improved” tea bags release millions of plastic microparticles; The surprising trigger of a bout of hives. 

Nutrition Nugget! Bite-size bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about Giving. As we enter the season of generosity, it's important to remember that even small acts of giving can make a big impact by signaling to our brain that we are safe, which can help replenish our willpower. Not only that, studies show that giving can lower stress, support balanced blood pressure, and even boost our immune system, making it a powerful tool for improving our physical and mental well-being. When you give, however, don't forget yourself, because you deserve it too. Tune in as Jenn explains the health benefits of generosity. Like what you're hearing? Be sure to check out the full-length episodes of new releases every Wednesday.  Have an idea for a nutrition nugget?  Submit it here: https://asaladwithasideoffries.com/index.php/contact/       RESOURCES:Become A Member of Salad with a Side of FriesJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramWillpower Won't PowerThe Longevity EquationBlue Zones: A Blueprint for Physical and Mental Health

Your liver and arteries work together to keep you healthy, but exposure to different stressors can affect both—potentially leading to serious health concerns. Top stressors to the liver and arteries: • Smoking • Alcohol • Drugs • Toxins • Viruses • Bacteria • Junk food • Sugar • Seed oils • Refined carbohydrates The two most powerful foods for liver and blood vessel health are garlic and onions. They are packed with antioxidants and may help with issues like oxidation, inflammation, fibrosis, and calcification. Garlic and onions are also liver-cleansing foods. They're both high in sulfur, which is involved in the body's detoxification processes. This is crucial to help deal with exposure to different stressors. More onion and garlic benefits: • Antimicrobial properties • Natural blood thinning effects • Improves insulin sensitivity • Optimizes lipids • Increases bile • Prevents bile sludge • Promote healthy blood pressure You can easily include these powerful ingredients in your diet in various ways, from stews to salad dressings and even keto pizza. Be sure to use fresh garlic and onion for the most potent effects.

Dr. Rachel Bennett is an Assistant Professor in Neurology at Massachusetts General Hospital and Harvard Medical School. Research in Rachel's lab focuses on understanding how blood vessels in the brain change in disease and how this might contribute to the loss of neurons in Alzheimer's disease. Rachel grew up on the West Coast of the U.S. and loved exploring the nearby mountains. This is something she has missed since moving to Boston, MA, so she recently started hiking some of the 48 peaks over 4,000 feet in New Hampshire in her free time. She also enjoys visiting the beautiful beaches nearby. Getting outside is a good reset button for her to recover from the stresses of work in the lab. She received her B.S. in Molecular Biology from Arizona State University and her Ph.D. in Neuroscience from Washington University in St. Louis. Afterwards, she conducted postdoctoral research at Harvard Medical School and Massachusetts General Hospital before joining the faculty there. Rachel has been named an Outstanding Emerging Scientist by the BrightFocus Foundation, and she received the New Investigator Award from the Charleston Conferences on Alzheimer's Disease (CCAD). In this interview, she shares more about her life and science.

Dan Nation is a professor of gerontology and medicine at USC. His research focuses on vascular factors in the brain and how they affect memory decline and dementia in older adults. He joined us to talk about studying blood vessels in the brain to identify early signs of dementia and potential therapies to treat it. Transcript Speaker 1 (00:01): The variability in your blood pressure day to day, month to month, year to year, and sometimes even beat to beat–the variability in your blood pressure is predictive of dementia risk. So higher levels of blood pressure variability are bad, even if you have very well controlled blood pressure levels. And this is important because currently we only treat average blood pressure. There is no treatment for variability in blood pressure. So it's a new area that we should try to look into controlling to see if we can prevent dementia in people who have high variation, even if they're already treated for hypertension. Speaker 2 (00:45): From the USC Leonard Davis School of Gerontology, this is Lessons in Lifespan Health, a podcast about the science and scientists improving how we live and age. I'm Orli Belman, Chief Communications Officer. On today's episode: how Professor Dan Nation is studying blood vessels in the brain to identify early signs of dementia and potential therapies to treat it. Dan Nation is a professor of gerontology and medicine at USC. His research focuses on vascular factors in the brain and how they affect memory decline and dementia in older adults. Welcome to our podcast Dan, and thank you for being here today. Speaker 1 (01:26): Thanks for having me. Speaker 2 (01:28): I wanna start by asking you about blood vessels in our brain. Is there anything unique about the brain's vasculature system, and how did it become the focus of your research? Speaker 1 (01:39): Yeah, it's a great question. So there's actually several things that are unique about the brain vasculature. For one thing, just the number of blood vessels. So you might think about the larger vessels that you can see with the naked eye, but most of the vessels are microscopic. And we have so many blood vessels in the brain that there's actually one blood vessel for every neuron. So every brain cell basically has its own microscopic blood vessel. So it's billions and billions of blood vessels, and this is likely the case because the brain has an incredible need for blood flow to support its very high metabolic rate. And the brain cannot store energy unlike other tissues in the body, and so any energy that the neurons need, they have to get on the fly from blood. So there's a torrential amount of blood flow that's disproportionate to the size of the brain. Speaker 1 (02:34): In addition to that, blood is actually toxic to brain tissue. And so the neurons need a special environment to operate, and so that milieu has to be well controlled. So the blood contains proteins, cells, infectious agents, metals, ions–all of which, if it were to get into the actual brain compartment, would be very toxic and would cause degeneration of the brain cells, cell death. And so their brain has a special structure that divides the blood off from the brain. This doesn't exist in other parts of our body; it's called the blood brain barrier. So that has to have integrity in order for the brain to survive and function properly. In addition, because of that, the way waste products of regular cellular metabolism and so forth, any other toxins that are in the brain, the way that gets moved out of the brain is different than other parts of the body because the lymphatic system in the brain is really different because we have to have this blood-brain barrier. So for a number of different reasons, the vessels are special. A lot of it has to do with the blood-brain barrier because the separation of the blood from the brain means that all of the nutrients have to be pumped actively into the brain. And all of these, again, waste products have to be pumped actively out somehow. And so any dysfunction there could lead to the buildup of toxins in the brain, which would cause degeneration. Speaker 2 (04:11): So your PhD is in psychology, correct? Speaker 1 (04:14): Yeah, neuropsychology. Speaker 2 (04:15): Neuropsychology. So how did you get interested in the vascular system? Speaker 1 (04:19): Yeah, I actually have always studied the vascular system because I was in a neuroscience lab that was focused on relationship between behavior and cardiovascular disease and basically neurovascular function and in particular as a clinical neuropsychologist we're involved in treating patients with neurocognitive disorders of aging, like dementia of Alzheimer's disease. And so I became interested in how these neurovascular factors may contribute to those diseases and to cognitive decline from those experiences. Speaker 2 (04:54): This sounds like a very complex system. What happens to it as we age? Speaker 1 (04:58): So as we get older, most people will develop a number of different vascular changes or will be at risk for different age-related vascular diseases. The most common is hypertension or high blood pressure. As we get older, the odds of developing high blood pressure just go up and up, and ultimately if you live long enough, most people will develop hypertension at some point. The majority of people over the age 65 have high blood pressure. And so that has to do with changes in your overall vascular system that can lead to a hardening or stiffening of the arteries and development of specific changes in the way the blood vessels of the brain work, which can damage the blood-brain barrier, lead to leakage of blood into the brain, decreased blood flow to the brain. And also what we've found is that older adults, their micro blood vessels don't dilate as well, and so they need to be able to dilate in order to provide more blood flow as needed to support brain health. Speaker 2 (06:11): It sounds like you know a lot about what's happening and the inner workings of our brain. Have updated imaging technologies improved our understanding of the role of these small blood vessels, and what can you tell us about your research in this area? Speaker 1 (06:24): Yes, so brain MRI has been very useful because it's usually relatively non-invasive, and we can use MRI to actually study the functioning of these microscopic blood vessels that would be otherwise very difficult to study. And we can actually visualize some microscopic changes such as small bleeds in the brain because they have this blooming artifact on brain MR. So we can see things that are microscopic, and we can study how the blood vessels can dilate or constrict using brain MRI. And we can study whether anything is leaking from the blood into the brain using brain MRI. So there's a lot more that is happening in MRI science that we're constantly monitoring and trying to incorporate into our studies. So I think there will be further advances, and we'll be able to study brain blood vessels even better in the future. Speaker 2 (07:19): And when you look at brain blood vessels, are you looking , particularly, at these microscopic ones? Speaker 1 (07:24): Yeah, we study the blood flow through these microscopic vessels and also whether or not they're leaking the leakiness of these vessels. Speaker 2 (07:32): I listened to a talk you gave, and you mentioned something called a neurovascular unit. What role does that play in brain health or brain dysfunction? Speaker 1 (07:41): It's a relatively newer concept that sort of springs off of the fact that again, there's a blood vessel for every neuron in your brain. It becomes clear when you understand how dense the micro vasculature is in the brain, that really it can't be totally separated from the functioning of the neurons themselves. When an area of your brain becomes active and neurons increase their activity, they need more blood flow, more nutrients, more clearance of waste, more oxygenation. And so they actually send a signal to other cells that control how much blood flow is happening, how much blood flow is coming to the vessels. So the blood vessels and the neurons are connected and communicating with each other. And so it's become clear that there's really this micro organ that we call the neurovascular unit, which is comprised of the blood vessel cells themselves, the neurons and other support cells, astrocytes, pericytes. And so all these different cells work together as a unit to make sure that blood flow meets the neurons' metabolic demand. Speaker 2 (08:50): And when this isn't working correctly, why is early detection of dysfunction in this area so important? Speaker 1 (08:56): Yeah, it's extremely important because if you think about it, when you have a problem with the blood vessel that could predate the actual injury to the brain, you can have dysfunctional blood vessels, but that doesn't mean you have any brain damage yet. You just have vascular disease. The blood vessels have a disease happening within them, but that can ultimately lead to death of the brain tissue. And in the brain, once tissue is dead, those neurons died. They're not replaced, and the brain can kind of rewire itself, but it can't really regrow that brain tissue. So the idea is if you cannot detect the blood vessel problem before the brain injury has happened, then you could intervene and prevent irreversible brain damage. Speaker 2 (09:47): That sounds important. How would somebody know? How do you test for blood vessel function? Speaker 1 (09:52): So, as I mentioned, we're using brain MRI technology. We're also working on blood tests. There's different markers people are interested in. It's still, you know, at the research phase, but we have the ability to quantify how well your blood vessels are responding to stimuli, how much blood flow you have into sensitive areas of your brain that are very important for memory and other mental functions and whether those vessels are leaking, which could lead to, again, irreversible brain damage. Speaker 2 (10:27): What can we do to improve our vascular health? Speaker 1 (10:30): So the number one thing is, well first of all to monitor your vascular health through going to see your physician so that you can catch cardiovascular risk factors early. If your blood pressure is elevated, if you have a problem with your cholesterol levels, if you're pre-diabetic or diabetic, it's extremely important that those cardiovascular risk factors are caught early and are well controlled and treated right away. If they are, they're not likely to lead to brain damage, but if they're left untreated, then you have a very high risk of this ultimately damaging your brain. The other thing is basic stuff that you would do for heart health is also good for brain health. So things like a good healthy diet, exercise. Physical activity doesn't have to be running marathons. Moderate levels of physical activity are helpful for the blood vessels in your brain. Speaker 2 (11:31): That's certainly a message we've heard on this podcast before: what's good for the heart is good for the brain. I think most people are familiar with the idea of high or low blood pressure, but you're looking at something called blood pressure variability. What is that, and what do we know about its connection to dementia risk? Speaker 1 (11:48): Yeah, so as I mentioned, many people over the age of 65 are going to have high blood pressure, and those rates just go up and up. But the research has shown that once you're over 65, if you have high blood pressure, develop high blood pressure, and as long as it's being treated, your actual blood pressure level doesn't really correlate with dementia risk very much. I mean, it needs to be treated; that's important. We know that. But beyond that, where you're at with your blood pressure as an older adult hasn't been very predictive of things like brain degeneration, dementia. But what we've observed is that, even if you are treated and even if you are treated pretty aggressively, have have very low blood pressure with treatment, the variability in your blood pressure day to day, month to month, year to year, and sometimes even beat to beat the variability in your blood pressure is predictive of dementia risk. So higher levels of blood pressure variability are bad, even if you have very well controlled blood pressure levels. And this is important because currently we only treat average blood pressure. There is no treatment for variability in blood pressure. So it's a new area that we should try to look into controlling to see if we can prevent dementia in people who have high variation, even if they're already treated for hypertension. Speaker 2 (13:18): And are the traditional treatments effective? Has your research revealed anything about blood pressure medications and whether they can affect variability? Speaker 1 (13:27): Yeah, we're just now starting to do this work. It's complicated because there's many different things that affect blood pressure variability, and we need to do a lot more research. But it's already known that medications that are longer lasting, drugs that have a longer half-life or have longer term effects, for example, those tend to be better at keeping variability low in addition to keeping your blood pressure levels low. And that makes sense, right? If the drug is wearing off, you know, after a short period of time or by the end of the day, then you would expect to have more variation between doses. And so we plan to do more research on the different types of blood pressure medicines, the classes, specific agents, and we'll call their pharmacokinetic properties, how long they last in your blood, the half-life and so forth. But also adherence to blood pressure medication if people skip a dose or they're taking it at the wrong time of day–that kind of thing can also affect blood pressure variability. Speaker 2 (14:28): And is this research that's still in the lab stage, or is this informing clinical practice yet? Speaker 1 (14:36): Well it's clinical research,  so we're studying human beings, older adults from the community who are taking blood pressure medications and that kind of thing. So it should, you know, our findings will be of value to clinicians, I think. And they're very interested in anything as it relates to blood pressure medicines because they're dispensing these drugs all the time in such a common condition. Speaker 2 (14:58): We have talked to Mara Mather about heart rate variability in this podcast, and I know that's a big area of research for her. Is there a connection between heart rate variability and blood pressure variability? Speaker 1 (15:11): Yeah, they're different things, but they are connected in the sense that your body tries to maintain steady blood pressure. It's not necessarily a good thing to have your blood pressure fluctuating all the time. And one of the ways that that happens, just homeostatically with normal functioning of your physiology, is changes in heart rate can help to modulate blood pressure. So they are related in terms of your cardiovascular system, but they're distinct. High heart rate variability is probably a good thing in relation to better health, whereas high blood pressure variability is a bad thing. Speaker 2 (15:48): This is a little bit of a subject change, but can damage blood vessels repair or regenerate themselves? And what might this mean for cognitive decline? Speaker 1 (15:58): Yeah, so anytime you receive any kind of injury, including a brain injury, the blood vessels and the tissue goes through a regeneration, healing restoration process. And in this case, usually it's the branching of additional vessels off of the existing vasculature. This is a process called angiogenesis, generating new branch points off of the blood vessel. So, if somebody has a stroke for example, you're gonna have a large piece of brain tissue that has been destroyed by not getting any blood flow. There's going to be a healing process that's gonna happen there, and there's gonna be some regrowth of branches of neurons as the brain kind of rewires itself and people healing from a stroke. And that has to be supported by branching off of blood vessels. So I said the neurons are very dependent on blood flow. So they work together during wound healing. And so yes, we certainly have an interest in this process since it's likely ongoing if you have some kind of microvascular damage happening, and we wanna understand more about whether it could be of benefit or it could go wrong and potentially cause harm and so forth. So we're studying this angiogenesis process in people with cognitive impairment. Speaker 2 (17:18): And can you tell me a little bit about how you're studying it? Speaker 1 (17:21): Yes. So we have lots of different projects happening. We are studying these cells that are in your blood circulation and come from different parts of your body, and they're very important in this angiogenesis process. They can actually form new blood vessels to replace damaged or dysfunctional ones. And so we can take blood from, again, older adults in the community who may or may not have different levels of vascular damage in their brains. And we can grow these cells in a dish and try to better understand whether they're functioning well, whether they're able to form blood vessels the way they're supposed to or if there's something wrong with that process. Speaker 2 (18:06): Is this what you're talking about when you say growing a brain in the lab? Speaker 1 (18:09): Yeah, so I've partnered with a bioengineering team that grows these micro brains, little brains in a dish. And what we can do now, and this is our new initiative we just started, is we can take blood from our participants and actually grow their brain vasculature in a dish. So these brain micro vessels that we're studying with brain MRI, we can actually grow them in the dish from these blood samples because we can grow these specialized cells that I'm referring to. They'll grow blood vessels in a dish, and we can see how they function. Are they forming blood vessels that are leaking? Are they forming blood vessels that are not branching properly or have other kinds of dysfunctional properties that don't support blood flow and so forth? And then we can tie that back to what's happening with that person's brain MRI. Do they have leaky blood vessels in their brains? Do they have proper blood flow on brain MRI or not? And so by doing this process, we can actually, the goal is to develop this sort of personalized medicine approach to try and better diagnose and treat brain blood vessel problems. Speaker 2 (19:19): So everybody's brain grows differently in a dish depending on what you're putting in? Speaker 1 (19:25): Yeah, this is what we're testing. So just let me give you a concrete example. If somebody has cognitive impairment and we do a brain MRI and we see that, sure enough, they have leaky blood vessels, might it be the case that this regeneration process isn't working in that person? So we could take their blood and grow a little mini brain that has their brain blood vessels in it and see whether they're leaking or not. If they are leaking, then it suggests that perhaps there's something wrong with this regeneration process, and we can actually try out different drugs in the dish and treat that person's micro brain with different potential therapies and see if any of them work. And then that might give us a clue as to how to fix the problem. Speaker 2 (20:07): Wow, that's really exciting. Is there anything you wanna add or any of your other research studies that you wanna give us an overview of?  Speaker 1 (20:14): Yeah, I think the only other thing I would wanna highlight, something that I'm really excited about that we've made a number of discoveries on and are continuing to, and we actually have some papers just now coming out, is this connection between memory decline and dementia and the functioning of these tiny blood vessels, these micro vessels. We've continued to find that the memory centers in the brain, which are the same areas that are affected by Alzheimer's disease and that degenerate in neurodegenerative disease that causes a really bad memory problem and dementia in older adults, the microvessels in those areas are dysfunctional in people who are at genetic risk for Alzheimer's. And in people who have memory problems, we found that they're leaking. We found that they don't dilate properly when we give them a stimulus that's supposed to dilate the blood vessels. And in some cases they have decreased blood flow. And so it's important because it demonstrates that there is this connection between the micro vessel function and neuro degeneration, which has, I think, eluded the research committee for a long time. We've known that there's a connection between vascular disease and neurodegeneration, but that's something I'm very interested in unpacking. Speaker 2 (21:33): Just to follow up on that, I know we hear a lot about the plaques and the tangles that are associated with Alzheimer's disease. Where does the vascular system come into play with this? Is there a connection? Speaker 1 (21:44): Yeah, so the way we normally think about Alzheimer's disease is that it has, as you mentioned, these two proteins that build up. You could form the plaques and the tangles, but also ever since Alois Alzheimer first described the disease, he noticed that there were problems with the blood vessels, a condition called cerebral amyloid angiopathy, where there's also a buildup of toxic proteins in the blood vessels. And it's been noticed again over the decades that a lot of cardiovascular risk factors are also risk factors for Alzheimer's, but no one was able to quite figure out how the blood vessel changes relate to Alzheimer's disease. And I think it's only just now that we're able to study these micro vessels with newer technology, that we're understanding that the micro vasculature is probably where this link is occurring. And what we've found is that there's a connection to the tangles, the tangles that are happening inside the neurons that lead to degeneration of those neurons. When you have microvascular dysfunction, you tend to see that kind of degeneration happening. Speaker 2 (22:52): Wow. This is a really interesting window into a whole new research direction that we haven't learned about before. So thank you very much for joining us today and explaining it all to us. Speaker 1 (23:01): Thank you. Speaker 2 (23:03): That wraps up this Lesson in Lifespan Health. Thanks to Professor Dan Nation for his time and expertise and to all of you for choosing to listen. Join us next time for another Lesson in Lifespan Health, and please subscribe to our podcast at lifespan health.usc.edu. Lessons in Lifespan Health is supported by the Nay Center for Healthspan Science.

In this episode of "Discover Daily" by Perplexity, we explore groundbreaking advancements in space technology, astronaut missions, and defense innovation. SpaceX unveils its latest Raptor 3 engine, boasting increased thrust, reduced mass, and improved efficiency. We also discuss the unexpected extended stay of two NASA astronauts on the International Space Station due to issues with Boeing's Starliner spacecraft.The episode then delves into the world of defense technology, focusing on Anduril Industries' recent $1.5 billion funding round, valuing the company at $14 billion. Founded by Palmer Luckey, Anduril is revolutionizing American defense manufacturing with autonomous military systems and innovative software-defined platforms.Our big story of the day looks new research in 3D printing artificial blood vessels, bringing us closer to creating functional artificial organs. We discuss the new coaxial SWIFT method developed by Harvard researchers, which enables the creation of complex, multilayered vascular networks within living tissues. This advancement holds promise for addressing organ shortages and advancing regenerative medicine, potentially transforming the future of healthcare and organ transplantation.From Perplexity's Discover Feed:https://www.perplexity.ai/page/the-evolution-of-space-x-rapto-4wkSpIEERRy96C2EYwjGrghttps://www.perplexity.ai/page/stuck-astronauts-will-return-i-00a_0jYZRKGrA38tE5uaGAhttps://www.perplexity.ai/page/defence-tech-anduril-hits-14b-ZeHfS6seRCSRPwp4qitrbghttps://www.perplexity.ai/page/3d-printed-blood-vessels-iUJTfBrcRPS3vm6sCmhYqQPerplexity is the fastest and most powerful way to search the web. Perplexity crawls the web and curates the most relevant and up-to-date sources (from academic papers to Reddit threads) to create the perfect response to any question or topic you're interested in. Take the world's knowledge with you anywhere. Available on iOS and Android Join our growing Discord community for the latest updates and exclusive content. Follow us on: Instagram Threads X (Twitter) YouTube Linkedin

Today we're finding out how to improve blood vessel health with New York Times best selling author, Dr. William Li. Dr. Li has some simple steps we can take to not only slow down the deterioration of our blood vessels, but also to reduce any existing blockages that we may, or may not yet know about. Learn how your body responds to food with ZOE

Today, you'll learn about a newly discovered deep sea ghost shark, the best way to treat prolonged grief disorder, and how the blood vessels in our brain coordinate to improve brain functioning. Ghost Shark “‘Ghost shark' with enormous head and giant iridescent eyes discovered off Thailand.” by Elise Poore. 2024. “Chimaera.” Shark Trust. 2020. “Chimaera supapae (Holocephali: Chimaeriformes: Chimaeridae), a new species of chimaera from the Andaman Sea of Thailand.” by David A. Ebert, et al. 2024. Grief Treatment “Which therapy works best to treat prolonged grief disorder?” by Lachlan Gilbert. 2024. “Cognitive Behavior Therapy vs Mindfulness in Treatment of Prolonged Grief Disorder.” by Richard A. Bryant, et al. 2024. “Comparing the efficacy of mindfulness-based therapy and cognitive-behavioral therapy for depression in head-to-head randomized controlled trials: A systematic review and meta-analysis of equivalence.” by Kristine Tretto Sverre, et al. 2022. “Prolonged Grief Disorder.” Psychology Today. N.d. Blood Vessel Coordination “Coordinating Blood Vessel Activity Might be Associated with Better Brain Performance.” Tohoku University. 2024. “Plastic vasomotion entrainment.” by Daichi Sasaki, et al. 2024. Follow Curiosity Daily on your favorite podcast app to get smarter with Calli and Nate — for free! Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers. Hosted on Acast. See acast.com/privacy for more information.

Dr Ferdinand Hui is a rare gem of a surgeon- brilliant in his craft, able to communicate complicated concepts clearly, and caring and compassionate for the reality that disease can impart in the life of a person and their family. Here we get a chance to cruise around the blood vessels of the brain with a neurointerventional surgeon, who's focus is minimally invasive procedures to treat the blood vessels of the brain and spine. Although he thinks of himself as a plumber, rotor-rootering the pipes, these are live pipes and much of our discussion centers on the nature of the arteries and veins. We discuss leaks (hemorrhage) and clogs (ischemic clots) as a starting point, with the associated diseases of stroke, heart attack and aneurysms. Then we get deep with the 'gray zone' of reduced but not necessarily stopped oxygenation which can be a primary driver for brain fog. We discuss anatomical, functional and inflammatory interruptions to oxygenation and vessel flow, even down to the epithelial layer of the arterial vessel walls. Here is where we discuss COVID and the apparent epithelial shedding that the spike protein can instigate, which likely drove much of the cardiovascular events (heart attack, stroke) of the first COVID wave in 2019/ early 2020. About prevention, Dr Hui says, "The American medical system might really reward surgery but what humanity really needs is prevention. Prevention starts at birth." Resources: Society of Neurointerventional Surgery: https://www.snisonline.org/ More about Dr Hui: https://www.queens.org/providers/2225/ferdinand-k-hui/

Episode #319. Join me today as I sit down with a very special guest: my dad, Professor Michael Hill, PhD. Dad's journey as a scientist has inspired my own work and taken our family across the globe, and I'm honoured to host him as he shares his story from early career discoveries to current research. As well as getting an inside look at Dr Hill's academic career, you'll learn about microvasculature (very small blood vessels), including what they are and how they impact human health. Dad also shares his experience with a heart attack, offers advice on preventing atherosclerosis, and weighs in on the Ozempic and vaping conversations. Specifically, we discuss: Introduction (00:00) Childhood Memories and Early Interests (03:19) Pursuing a Career in Biochemistry (08:36) Microvasculature and Diabetes Research (12:12) Early Research on Investigating Blood Properties and Diabetes (17:44) Family Stories and Moving to the U.S. (28:47) Returning to Australia and Continued Research (36:39) Exploring Microvessel Behaviours: Research at RMIT (41:34) Dealing with Health Challenges and Maintaining Work-Life Balance (46:20) Understanding Microvascular Functions and Cardiac Health (50:32) Exploring Vessel Constriction and Small Blockages: A Closer Look (01:00:15) Understanding the Impact of Large Arterial Stiffness on Vascular Health (01:07:01) Identifying Risk Factors: A Comprehensive Approach to Vascular Well-being (01:11:01) Personal Views on the Evolution of Scientific Research Access (01:19:39) Returning to the USA: Advancing Research on Blood Vessel Mechanisms (01:21:58) COVID-19 and Metabolic Syndromes: Exploring the Early Research Connections (01:27:30) Current Research and Future Directions (01:29:29) Reflecting on a Career Dedicated to Science: Family, Achievements, and Future Directions (01:34:48) If you're interested in learning more about Dad's work and career, head to his profile here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. BON CHARGE Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

They giveth and they taketh away.

The audio for this podcast was extracted from a YouTube video that was recorded at an earlier time. While the information in the video is still valuable, some of the content might be date-specific. If you want to watch the video, please follow this link: ⁠The Blood Vessel Health Secrets Big Pharma Doesn't Want You to Know Don't know where to start on your journey to better health and living? Get a copy of my FREE book here: https://www.livingooddailybook.com Shop all Livingood Daily Products on Amazon here: https://www.amazon.com/stores/page/6FF3F801-3EFC-4A52-A87E-5E98139627C3 Follow and listen to Dr. Livingood on any of these platforms: YouTube: https://www.youtube.com/@DrLivingood Facebook - https://www.facebook.com/drlivingood Instagram - https://www.instagram.com/drlivingood/ TikTok - https://www.tiktok.com/@drlivingood Pinterest - https://www.pinterest.com/drlivingood... Blog - https://drlivingood.com/real-health/ http://Medium.com - https://medium.com/@drblakelivingood LinkedIn: https://www.linkedin.com/in/drlivingood/ Twitter: https://twitter.com/doctorlivingood DISCLAIMER: Dr. Blake Livingood is a licensed Chiropractor in North Carolina and Florida, he founded a clinic in North Carolina but no longer sees patients. He received his Doctor of Chiropractic degree from Life University in 2009. Dr. Livingood uses “doctor” or “Dr.” solely in relation to his degree. This video is for informational purposes only and should not be used as a reason to self-diagnose or as a substitute for diagnosis, medical exam, treatment, prescription, or cure. It also does not create a doctor-patient relationship between you and Dr. Livingood. You should not make any changes to your health regimen or diet before consulting a qualified health provider. Questions regarding your personal health conditions should be directed to your physician or other qualified health providers.

55 million people suffer dementia worldwide with numbers expected to double every 20 years. Understanding the link between our heart health and brain function is critical, illuminating the profound impact that heart health has on preventing dementia.Dr. William Li, an expert in cardiovascular and metabolic health. He reveals how caring for our heart is not just about longevity but maintaining sharp, effective brain function as we age. His groundbreaking work has impacted more than seventy diseases including diabetes, heart disease, and obesity. Dr. Li is also a New York Times best-selling author.In today's episode, Dr. Li explains how simple lifestyle choices in diet, exercise and sleep can drastically shape our brain's health and stave off dementia.If you want to uncover the right foods for your body, head to zoe.com/podcast, and get 10% off your membership.Follow ZOE on InstagramTimecodes00:00 Introduction01:23 Quickfire questions03:30 Understanding dementia and Alzheimer's disease04:50 Dementia versus ageing06:35 The role of blood vessels in brain health07:55 How circulation affects brain function09:23 What causes blood clots and strokes?11:06 The importance of maintaining healthy blood vessels12:15 The impact of lifestyle choices on brain health15:01 What happens in our brains when we sleep?19:35 What is the glymphatic system?22:40 Vascular dementia may be the most common form of dementia24:35 The role of glucose in brain function27:10 What causes dementia and why does it happen when we get older?29:00 Preventing dementia with lifestyle changes31:10 What are healthy blood vessels like?37:50 The surprising role of EPCs in brain repair41:30 Can you slow down or reverse dementia?52:08 The connection between gut health and brain health51:40 The importance of exercise for brain health56:30 How to avoid dementia01:01:16 The link between mental health and cardiovascular diseaseRelevant studies:A human brain vascular atlas reveals diverse mediators of Alzheimer's risk, published in NatureHeart-brain connections: Phenotypic and genetic insights from magnetic resonance images, published in ScienceCocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study—a randomized controlled trial, published in The American Journal of Clinical NutritionDr. William Li's books:Eat to Beat Your DietEat to Beat Disease Is there a nutrition topic you'd like us to explore? Email us at podcast@joinzoe.com, and we'll do our best to cover it. Episode transcripts are available here.

Originally Recorded on Saturday April 13th and Saturday April 20th, 2024 Hello there, fans! That Horror Show Podcast brings you a brand new episode for the beginning of the May season...but, just to be clear, this episode is not May-related. Anyways, those lovable dummies Timothy Kazda and Chris Koenig tackle another double-feature of fear and fright. And, wouldn't you know it, the two films take place during World War 2! Pop quiz, class: did you know the Allies were fighting against zombie supermen and Romanian blood-suckers on the side? If you didn't know that piece of ancient history, then you are in for a treat with this episode. Tune in to hear the hosts talk about "Overlord" (2018), a wild tale involving American G.I.'s battling against evil Nazi's (really, are there any other kind?) and the Third Reich's secret experimentation in the creation of superhuman soldiers from beyond the grave! And then, the hosts turn their sights towards the rather witty title "Blood Vessel" (2019) in which those wild and crazy Nazi's have unleashed an ancient Romanian blood-drinking creature on a ship that threatens some Allied survivors! Oh, and Nate of 'Kids Corner' just got his draft papers and he's about to tackle "Tucker & Dale vs. Evil" (2010). So grab your rifle and bayonet, make sure you have plenty of Lucky Strike's to smoke-up, and give this episode a listen, soldier!   #Overlord #BloodVessel #TuckerandDaleVsEvil #DeathShip #WWII #Zombies #Vampires #THSP 

If there was a natural way to get balanced, healthy blood pressure and support a healthy cardiovascular system, without pharmaceuticals, wouldn't you like to know? Well there is! Lifestyle and dietary factors are always first and foremost, but there are also some key supplements that not only promote healthy blood pressure levels but also a healthier cardiovascular system. As always, Jared is looking for better and healthier options without the need for pharmaceutical interventions. On this episode of Vitality Radio, Jared explains vascular aging and what you can do about it from a supplemental standpoint. You'll learn the current science behind this approach and what products you might want to consider to get your blood pressure back in check.Products:Redmond Real SaltRe-Lyte HydrationEndure electrolyte dropsVital 5 Magnesium BisglycinateN.O. Cardio BoostAged Garlic ExtractBerberineOPC Clinical 400mgAdditional Information:#395: How Aged Garlic Extract Benefits Every System In Your Body with Dr. Jim LaValle#278: The Incredible Benefits of Aged Garlic Extract#227: VR Vintage: There is an Herbal Supplement that Works for Diabetes, Blood Pressure and Cholesterol Better than Drugs! Berberine is that Powerful!#120 VR Vintage: Restoring Your Immune Ecosystem with Dr. Zach BushBe Healthy Utah discount code: vitality40Visit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Biden throws out more nonsense "facts" about new jobs, Dr. Drew doesn't trust the media and explains why, a "new" disease that is likely a coverup for the failed gene-therapy experiment and much more! Click here to ⁠⁠Join The SwoleFam 20% OFF ALL MERCH! PapaSwolio.com Watch the full episodes here: Subscribe on Rumble Submit A Question⁠ For The Show  Use Code "GTTFG" to get 10% OFF ALL MERCH! Get On Papa Swolio's Email List Download The 7 Pillars Ebook  Try A Swolega Class From Inside Swolenormous X  Get Your Free $10 In Bitcoin    Questions? Email Us: Support@Swolenormous.com

Dr. Axel Montagne, Ph.D., Chancellor's Fellow & UK DRI Group Leader at The University of Edinburgh, joins Jillian this week to explain everything we need to know about the causes of dementia and whether or not we can prevent it. From the degradation of our blood brain barrier, to small blood vessel disease, Alzheimer's and amyloid plaques, to what you need to know if you are genetically predisposed by having certain APOE genes. We also discuss the link between insulin resistance and cognitive decline and what you can do to treat dementia with exercise, sauna therapy, sleep, fish oil, and the newest drugs on the market. Guest Links:Website: https://montagnelab.comX (Twitter): @MontagneLab and @AxL_Montagne For 25% off The Fitness App by Jillian Michaels, go to www.thefitnessapp.com/podcastdealFollow us on Instagram @JillianMichaels and @MartiniCindyJillian Michaels Community: https://www.facebook.com/groups/1880466198675549Email your questions to JillianPodcast@gmail.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.