Podcasts about Corpus callosum

Episode: 3301 Gustav Fechner and the origins of psychophysics.  Today, Gustav Fechner and the mathematics of the senses.

PART 1 of a compilation of one of Karl Pilkington's most beloved features, MONKEY NEWS; and the utterly pointless spin-off feature, CHEAP AS CHIMPS, as well as a smattering of other random monkey bits. Monkeys are near and dear to Karl's simian heart. He spent much of his time during the XFM years sitting at home, looking up spurious monkey facts on the Internet. He would then share this unreliable monkey-related drivel with his two best friends, Ricky Gervais and Stephen Merchant, who, over time, became increasingly irate at Karl's evermore outlandish monkey musings. **TO BE CONTINUED** Hairless Chimp Tries It On With Zookeeper's Wife (0:00) Chimp Does Time For Smoking (4:49) First Monkey To Have His Name Tattooed On His Head (7:18) Infinite Monkey Shakespeare Conundrum (15:58) Hackney Chimp Nickin' DVDs (26:49) Corpus Callosum (30:56) Bonobos (33:40) Monkey In India Trips a Fella (39:07) Oliver the Humanzee (40:05) Invention of CHEAP AS CHIMPS (48:37) Monkeys Havin' a Chat (49:51) CHEAP AS CHIMPS - How Many Bananas? (52:50) Koko the Gorilla (55:48) CHEAP AS CHIMPS - How much does a chimp cost? (59:53) Monkey Wedding (1:02:47) Monkey Bank Robber (1:06:37)

Meet warrior, Alex. Alex is transgender identifying as trans-masculine and non-binary. From a young age, Alex endured many chronic illnesses and disabilities. He/They was later diagnosed with Agenesis of the Corpus Callosum, a rare brain disorder where there is a partial or complete absence of an area of the brain that connects the two cerebral hemispheres. Alex also manages Dandy-Walker Syndrome, a congenital brain malformation involving the cerebellum and the fluid-filled spaces around it that coordinates movement, and additionally lives with blindness in the right eye, arthritis, chronic pain, non-verbal learning disorder, depression, anxiety, PTSD, OCD, autism, and more. Alex works hard to support the disabled community as a full-time Disability Resource Specialist, as well as strives to care for his/their own health. Alex not only faces tremendous obstacles living with multiple, rare conditions, but he/they faces another huge hurdle; Alex must navigate a healthcare system that doesn't truly accommodate or comprehend his/their needs as a transgender person. Listen as Alex shares his/their story, the challenges of being transgender and chronically ill, and how he/they supports his/their health and well-being.   

My guest today is Tanya English. She is a chiropractor from Iowa who has found healing through not only chiropractic care, as you normally think about it, but she also incorporates other techniques into her practice to support healing without "cracking" the bones. In this episode, she decreases some pain in my back. We also talk about the reticular activating system.The reticular activating system (RAS) is a collection of nerve fibers that filter the sensory information to our brain. Without this system working efficiently, we would be mentally interrupted by every sensation around us. For example, have you ever had a tag on your clothes that just won't stop bugging you? Your RAS has not filtered the tactile sensation efficiently, so that you can ignore it.Listen in to allow Tanya to calm your day.Dr. Tanya Englishhttps://healingwiththeblues.com/https://www.linkedin.com/in/drtanyaenglish/drtanya@healingwiththeblues.comCheri Dottererhttps://www.cheridotterer.com/https://thewritingglitch.com/cheri@cheridotterer.com ★ Support this podcast ★

Split-Brain is the title given to the research into whether each hemisphere of the brain can learn independently from the other. A neurologic highway mending the two hemispheres called the Corpus Callosum was long believed to be a communication pathway that ultimately links the two sides together, making a cognitive individual known as, You. Many experiments were trialed in order to essentially temporarily shut down (or put to sleep) one hemisphere of a brain, while directly studying responses to different stimuli in the other hemisphere. Long story short, this propelled Michael Gazzaniga and his mentor Dr. Roger Sperry into many different experiments that eventually led to surgically separating the hemispheres of living human subjects leading to a massive explosion of incredible knowledge about our consciousness. Or, BOTH of our consciousnesses. You heard me right travelers, essentially, there are two of you. One in the left hemisphere of your brain, that we are all aware of. This is essentially, YOU. This is the side that is responsible for conversation and other tasks that we rely on every day. And one in the Right hemisphere of your brain that is and has been muted, blocked, and hidden away for their entire life. Don't believe me? Good. Let me help change your mind. Welcome Back to Infinite Rabbit Hole! -Jeremy

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.05.04.539362v1?rss=1 Authors: Martins-Costa, C., Pham, V. A., Wiegers, A., Sidhaye, J., Doleschall, B., Novatchkova, M., Lendl, T., Piber, M., Peer, A., Moeseneder, P., Stuempflen, M., Chow, S. Y. A., Seidl, R., Prayer, D., Hoeftberger, R., Kasprian, G., Ikeuchi, Y., Corsini, N., Knoblich, J. A. Abstract: Mutations in ARID1B, a member of the mSWI/SNF complex, cause severe neurodevelopmental phenotypes with elusive mechanisms in humans. The most common structural abnormality in the brain of ARID1B patients is agenesis of the corpus callosum (ACC). This condition is characterized by a partial or complete absence of the corpus callosum (CC), an interhemispheric white matter tract that connects distant cortical regions. Using human neural organoids, we identify a vulnerability of callosal projection neurons (CPNs) to ARID1B haploinsufficiency, resulting in abnormal maturation trajectories and dysregulation of transcriptional programs of CC development. Through a novel in vitro model of the CC tract, we demonstrate that ARID1B mutations reduce the proportion of CPNs capable of forming long-range projections, leading to structural underconnectivity phenotypes. Our study uncovers new functions of the mSWI/SNF during human corticogenesis, identifying cell-autonomous defects in axonogenesis as a cause of ACC in ARID1B patients. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

The Corpus Callosum, Latin for “tough body”, is a bundle of nerves that serve to send signals from both hemispheres to the other and to allow for hemisphere-hemisphere communication of sensory, motor, and cognitive information. It's the largest white matter structure in the brain and has approximately 300 million nerve fibers, on average. In this fast-facts episode, Edward reviews the Corpus Callosum's form and function, as well as the key features that make us who we are.To create this episode, I used information provided by the Queensland Brain Institute, which can be found here: https://qbi.uq.edu.au/brain/brain-anatomy/corpus-callosumNo statement, phrase, or episode of this series—or any episode in this podcast—are intended to treat, diagnose, cure, prevent, or otherwise change your mind or body in any form or manner. This podcast—and this series especially—is meant purely for education purposes for the common person. Please do not rely on any of the information I share in this podcast in any way for your medical or psychological treatment. If you feel that you may have a condition mentioned or not mentioned in this podcast, do not come to me. Instead, immediately go to a trusted psychiatrist, psychologist, therapist, counselor, or other reliable source of information and help for further guidance. Never disregard professional, psychological, or medical advice—nor delay in the seeking of this advice—because of something that you have heard or read from this podcast, this podcast's episode descriptions, this podcast's promotional materials, or any other information explicitly or implicitly generated from this podcast.-----If you love this podcast, show your support by rating, subscribing, and downloading!  The best way to support me is by sharing this podcast with others—the more people can learn, the better we can understand the crazy world we live in :DI realize that this episode is coming back after a very long hiatus--I have had a few issues with my podcast server, but the rest of the episodes of this season will be published in the next few days :) Sorry for the delays and thank you for your patience!

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Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.14.516402v1?rss=1 Authors: Raaf, N., Westerhausen, R. Abstract: Originating from a series of morphometric studies conducted in the 1980s, it appears a widely held belief in cognitive neuroscience that the corpus callosum is larger in non-right handers than in right handers (RH). However, a recent meta-analysis challenges this belief by not finding significant differences in corpus callosum size between handedness groups. Yet, relying on the available published data, the meta-analysis was not able to account for a series of factors potential influencing its outcome, such as confounding effects of brain size differences and a restricted spatial resolution of previous callosal segmentation strategies. To address these remaining questions, we here analysed the midsagittal corpus callosum of N = 1057 participants from the Human Connectome Project (HCP 1200 Young Adults) to compare handedness groups based on consistency (e.g., consistent RH vs. mixed handers, MH) and direction of hand preference (e.g., RH vs. left handers). A possible relevance of brain-size differences was addressed by analysing callosal variability by both using forebrain volume (FBV) as covariate and utilising relative area (callosal area/thickness divided by FBV) as dependent variable. Callosal thickness was analysed at 100 measuring points along the structure to achieve high spatial resolution to detect subregional effects. However, neither of the conducted analyses was able to find significant handedness-related differences in callosal and the respective effect-sizes estimates were small. For example, comparing MH and consistent RH, the effect sizes for difference in callosal area were below a Cohen's d = 0.1 (irrespective of how FBV was included), and narrow confidence intervals allowed to exclude effects above |d| = 0.2. Analysing thickness, effect sizes were below d = 0.2 with confidence intervals not extending above |d| = 0.3. In this, the possible range of population effect sizes of hand preference on callosal morphology appears well below the effects commonly reported for factors like age, sex, or brain size. Effects on cognition or behaviour accordingly can be considered small, questioning the common practice to attribute performance differences between handedness groups to differences in callosal architecture. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Hello! I return!Today we will be talking about the neuroscience of seizures and epilepsy. Brought about an imbalance of the accelerators (excitatory circuits) and brakes (inhibitory circuits) of the brain, seizures are pretty terrifying events. They're marked by temporary confusion, a staring spell, uncontrollable jerking of the arms and legs (like what you see when someone depicts a seizure on gray's anatomy), loss of consciousness, or even some cognitive and emotional symptoms. Curious to find out what the heck the brain is up to during seizures? Come and listen to find out more!Please rate, review, and subscribe and if you have any questions, comments, concerns, queries, or complaints, please email me at neuroscienceamateurhour@gmail.com or DM me at NeuroscienceAmateurHour on Instagram.Also if you have the means/desire to financially support this podcast - please go to https://www.buymeacoffee.com/neuroscienceI really appreciate it!!!Citations and relevant papers are below! Types of Seizures. www.hopkinsmedicine.org. https://www.hopkinsmedicine.org/health/conditions-and-diseases/epilepsy/types-of-seizures#:~:text=Focal%20onset%20seizures%20start%20inRs F, Jh C, Ja F, et al. Operational Classification of Seizure Types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia. Published April 1, 2017. https://pubmed.ncbi.nlm.nih.gov/28276060/Types of Seizures. Epilepsy Foundation. https://www.epilepsy.com/what-is-epilepsy/seizure-typesArticles. Cedars-Sinai. https://www.cedars-sinai.org/health-library/diseases-and-conditions/m/myoclonic-epilepsy.htmlBromfield EB, Cavazos JE, Sirven JI. Basic Mechanisms Underlying Seizures and Epilepsy. Nih.gov. Published 2015. https://www.ncbi.nlm.nih.gov/books/NBK2510/Peng SJ, Hsin YL. Functional Connectivity of the Corpus Callosum in Epilepsy Patients with Secondarily Generalized Seizures. Frontiers in Neurology. 2017;8. doi:10.3389/fneur.2017.00446Kim T, Nguyen P, Pham N, et al. Epileptic Seizure Detection and Experimental Treatment: A Review. Frontiers in Neurology. 2020;11. doi:10.3389/fneur.2020.00701Ammothumkandy A, Ravina K, Wolseley V, et al. Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. Nature Neuroscience. 2022;25(4):493-503. doi:10.1038/s41593-022-01044-2CDKL5 cyclin dependent kinase like 5 [Homo sapiens (human)] - Gene - NCBI. www.ncbi.nlm.nih.gov. Accessed August 3, 2022. https://www.ncbi.nlm.nih.gov/gene/6792‌CDKL5 Deficiency Disorder. Epilepsy Foundation. Accessed August 3, 2022. https://www.epilepsy.com/causes/genetic/cdkl5-disorderSørensen AT, Kokaia M. Novel approaches to epilepsy treatment. Epilepsia. 2012;54(1):1-10. doi:10.1111/epi.12000Rogawski MA, Löscher W. The neurobiology of antiepileptic drugs. Nature Reviews Neuroscience. 2004;5(7):553-564. doi:10.1038/nrn1430Support the show

TrypSitter Binaural Beats combines two heart chakra frequencies to create the ultimate sound bath of healing and deliberate meditation. Two different frequencies play out of Left Stereo and Right Stereo. Creating a new frequency in the hearer's brain by way of the Corpus Callosum. Best used with Headphones! Disclaimer: do not use while operating machinery or driving. Binaural Beats Landing Page- https://www.trypsitter.live/binauralb... Podcast on Spotify - https://open.spotify.com/show/03V3dST... Psychedelic Shop on TrypSitter featuring Shaman Products, Tapestries, Energy Toys, Roller Skates and more! - https://www.trypsitter.live/shop Learn more about psychedelic molecules here- https://www.trypsitter.live/education Background music: Peaceful and harmonious, relaxing composition with an inspirational, calm atmosphere featuring floating, smooth pads and dreamy sounds. Perfect score for meditation, yoga tutorials, nature documentaries and landscape shots. Audio source: MusicRevolution © TrypSitter Inc. 2022 All Rights Reserved.

IntroToday we continue considering “the world inside of our head” as quite narrow versus “the world of your body”, pulling heavily from Matthew Crawford, but also Iris Murdoch and Iain McGilchrist.We are going to look a bit at the mind/body split that became the “my self is the voices in my head” problem. And hopefully cast some doubt on the intellect as a lone arbiter for decisions, and reintegrate the right brain and body. This is difficult because at our most foundational (linguistic) attitudes we consider the self as the intellect: Alan Watts says we often say “I have a body” when we ought to say “I am a body.”We tend to think the “I”, or “me”, is somehow located in the head: a “little man or woman or homunculus or demon” is watching out of our eyes and giving orders. The body is an extension that reports to and enacts the brain's commands at will: a type of machine that is controlled from on high. Yet, today, we can contradict this saying that ‘somehow' the body constitutes the self, and in many ways is more reliable than the little man/woman/demon between our ears who pretends to be in control.Matthew Crawford has shown us that living out of our heads, the ole Descartes dictum “I think therefore I am,” privileges the little man between our ears, who produces mental constructs that we start to identify with. This creates personal identities but is layered on top of deep subliminal cultural ideologies as well. Crawford shows us that our concepts, our mental models, morph easily and allow us to be manipulated. Especially through cultural indoctrination and advertising. (Step 53, Step 54)The problem is “inside of our heads” is the same place we go to do logic-y and math-y things, so going there for answers feels like rationality… it feels like we are making or finding the truth.A caveat: we need more rationality in a lot of areas, and overall it is fantastic (I am pro-rationality), but being truly rational is also realizing we are not always rational. We tend to cloak our non-rationality as rational (and over-indexing on logic), which leads to its own brutally reductive and efficient characteristics that (in many ways) are detrimental to humans. When I talk about “rationality or logic,” I am mostly referring to the cultural tendency to champion what Allan Watts calls the Cartesian net. This is a way of thinking where we throw a net or grid over the world, dividing it up so we can quantify, measure, and abstract the messy reality we encounter. And we do this internally to ourselves to borrow the gravitas, solidity, and cache of seemingly infallible objective truthiness of logic and math and science.“Truth was never high on the agenda for humans.”Yuval Noah HarariStep 56: Embodied PerceptionPart 1: How we got hereThe strength of humans may be our ability to communicate and share knowledge, and the biggest illness we may have is getting locked inside our own thought processes. “I think therefore I am” leaves us alone, thinking, which is how we end up with crazy people. Yet, somewhere along the way objective rationality won and we split the human into parts, categorically speaking, not literally.One split was the rational self and the will (or moral drive).Here's how it worked: you observed facts (a banana peel on the street), bring the data into yourself, make a determination (if I step on it I will slip), and then act (avoid the banana peel or pick it up so no one else slips on it). The action, observable to all, was your morality on display. (what kind of person are you, you selfish peel dodger?)Notice, nothing of the body in here, except to be observed enacting your virtues? The body is, if anything, not rational and historically maybe even evil, or at least lustful. (And who wouldn't be with all those banana peels laying around?)But more importantly for today: Notice how this determination of “who you are” parallels a type of scientific method: first, we collect data, then develop a theory, and finally test it with observable reaction.“Philosophy in the past has played the game of science partly because it thought it was science.”Iris MurdochShe said this back in the 60's and pointed out that philosophy and psychoanalysis are not science, they are broader and about human nature, but they tend to borrow from science some of the security of logic. But, Murdoch says philosophy and psychoanalysis cannot preclude the “inner self” or morality: We are born humans long before we become logical scientists.Step 56: Embodied Perception Part 2: Problem 1In Step 54 we discussed that through fMRI scans scientists can tell that when we “pause to deliberate” before making a decision our brain is only producing electrical chatter: not actual thought. This points to the notion that the decision is made either before we even began deliberation or made in some way not related to the brain. This is either scary or free-ing, but the implications are profound.Fascinatingly enough, in the philosophies of existentialism and surrealism, both acknowledge that when we're making difficult decisions there seems to be a “void” at the moment of choice, an “emptiness” when it is time to make the decision. Existentialists claim that “emptiness” is a sign of freedom to make a choice, while surrealists say that emptiness means there are no reasons, it is all chance.Iris Murdochsays when we have to make a difficult decision mostly we are enacting the behavior of thinking. We have learned to pause, stroke our beards, squint our eyes, and perhaps look upward with an out-of-focus gaze. We adopt the posture of deliberation, learned by watching others pretend to think.Murdoch says the “deciding” was already done previously: day by day in a piecemeal fashion we assemble who we are and how we will react through little habits and interactions.She says you are “free” – you have freedom- in the small seemingly inconsequential actions of your daily life. But when the big moral choice comes and you enter this strange state of “emptiness”… it seems like your “will” moves of its own accord.Problem 1 is that under stress, big decisions made at the moment, do not really look to rationality: It just happens. The right brain is nowhere to be found. Part 2: Problem 2Iain McGilchrist wrote an amazingly thick book that I purchased and have not yet read called “The Master and the Emissary“. But, I did listen to some podcasts where he talked about the left-brain right-brain split.But, as a caveat, Robert Sapolsky, who wrote the book “Behave,” says the left/right thing is overplayed.The Right-brain is the “master” who let his “emissary,” the Left-brain, do the talking. Now the ‘rational' LEFT brain begins to think it is in charge. so it talks all the time, and won't listen to the Right brain. Imagine a pompous King Author shooing off Merlin because he's in the middle of a real knee-slapper.“not now Merlin… and that's when he stepped on teh banana peel! haha”Now, the Left side of the brain (which controls the right side of the body) handles math, facts, sequence, logic, and articulates language, even though the right also understands language. The Right side of the brain handles feelings, intuition, and holistic thinking, often seen as creative.How do we know this? There have been experiments, conducted around 1960 by Roger Sperry with humans who had their corpus callosum cut to prevent epileptic seizures. (The Corpus Callosum is the bundle of nerves that connect the Left and Right hemispheres.)For instance, if the Left hand (which is controlled by the Right-brain with feelings and imagination and holistic thinking) is put into a box and the person is told to grab an object. Let's say the left hand (controlled by the right brain) grabs a hammer… when asked what the Left Hand is holding, the person will say something, like “a banana”… this is the Left side of the brain talking. It controls the speech centers. The left brain pretends to know, to be in control… so it lies.To make this even stranger, the Left hand, with the “hammer” will reach over and start trying to help, to show the other side (show the Left side of the brain) it is holding a banana. But the Left side of the brain will deny its help and continue lying, proclaiming it has been deceived.“Merlin tricked me again!”Problem 2: The left side of your brain lies. This is the logic side, which coincidentally is also the self-deception and confabulation part of the brain.Culturally, through science and philosophy, we have given control to a liar, who is great with focus, logic, and math, but maybe we should restrict his “authority” a little and put some checks and balances in place.Step 56: Embodied Perception Part 3: Embodied PerceptionEmbodied knowledge: the body has its own knowledge that is quicker, and more embedded than rationality.Embodied perception: the body collecting sensory data from your environment by engaging with it, moving through it.Have you ever moved before you knew something was wrong? Did you act without thought? Perhaps you just “felt” something that later turned out to be wise, but at the time you weren't thinking at all? This can be considered embodied perception. Your body's autonomic systems, your automatic nervous systems, pick up on cues before your rational mind can process them, and you react without the intervention or judgment of your brain.How far does this perception extend?Matthew Crawford discusses how our brain ceases to differentiate between a tool and our hand, the tool merely becomes an extension of our perception, an extension of our hand. Overtime, through familiarity, our perceptual range can extend, and our environmental range expands to new sensitivities. A primary point Crawford makes is that:“Perceiving is a way of acting. Perception is not something that happens to us, or in us. It is something we do. “Matthew CrawfordThis counters the assumption that the mind interprets perception: the body does it through action and movement, which means we perceive THROUGH the body, and it is filtering knowledge.About a year ago I listened to The Philosopher's Zone podcast on “Neurophenomenology and Sensemaking”. We aren't going to cover all of that, but in our techno-rationalized world, we tend to look for the one bolt that caused the problem: it is a reductive and isolationist way of thinking that fails to account for systemic variables and multiple cascading failures and reactions.But your body is built for holistic environmental sensemaking and holds knowledge that often supersedes what your logical brain can tell you. Speaking of Neurophenomenology, Brad Roberts quotes a guy named Claxton, who talks of“the human body as a massive, seething streaming collection of interconnected communicating systems, that binds the muscles, the stomach, the heart, the sensors in the brain so tightly together that no part especially the brain, can be seen as functionally separate from or senior to any other part.”ClaxtonOne of the examples given by Roberts, who has written his PhD thesis on sense making, is the Piper Alpha Oil Rig explosion where 167 people died, and 62 survived. Those who survived reacted to the felt heat and flames and jumped in the ocean, those who perished were insulated from the heat and waited for rescue. Those who perished had an impoverished perception of the environment: their physical sense of direct data was limited.Another example is Cpt Sully Sullenberger, the pilot who saved all those people by crash landing in the Hudson River, was reacting at the moment to an emerging situation, but after years of flying and practicing belly landings he knew the correct glide path: he had already mastered the technical proficiency which allowed him to react instinctually.This is interesting because it “sounds” like rational thinking in hindsight: I have the skills and knowledge, I recognize the situation, make a judgment, and react. YET… Crawford saysat High speeds judgment is not the right word because reaction is too fast, cognitive activity is costly and takes time ~ you literally feel the situation to process the data.To examine how the body computes versus intellectual computation Crawford discusses robot design.A robot has to interact with its environment. The old-fashioned way to do this was to compute all the variables before and during and after movement… it is grossly inefficient, all that computation. And as we know from behavioral economics and evolutionary science, thinking takes a lot of energy and we were designed to run in passive mode as much as possible. Robot Designers are now following an evolutionary (morphological) model. They find that the right design imparts feedback more efficiently than computation.for instance, With a bit of gravity on a downhill slope, a human can walk with virtually zero energy. Each step imparts more information through the movement: it tracks incline through increased or decreased gait, terrain through resistance, etc… Apply this evolutionary design to a robot and the mechanics impart information at low energy and reduced computation.To further underline the importance of locomotion as a means of cogitating or perceiving, Crawford says sight and movement are connected. He has cited some developmental examples with kittens on a merry-go-round. The brunt of it is: We perceive three-dimensionally through movement. Our awareness and cognition are through mapping the environment, gauging what the environment provides, and from there we are afforded possibilities.“When we perceive, we perceive in an idiom of possibilities for movement.”Alva NoeSo, when your motorcycle slips on that ever-present banana peel, you are gyroscopically correcting: it is almost as if the bike is your body. As you move through your environment, perceiving possibilities, you realize you can't correct the left without hitting oncoming traffic, and your body accounts for this through environmental awareness, without spending time rationally considering it. All of this is to save the ole noggin, which was dumb enough to get onto a motorcycle.Or, on a larger scale, taking into account the possibilities our environment affords, such as knowing the Hudson river is up ahead and being familiar enough with the plane to do a belly landing, allows Cpt Sully Sullenberger to save 155 people.Step 56: Embodied Perception Part 4: RecapWe are casting into doubt the over-reliance on internal logic. Because it is quite messy the way emotions and instinctual behaviors interact with your brain: it's not purely rational.Once again, we are a seething communication system. So tightly bound, the body and brain are really inseparable. Yet, of course, we keep trying to separate them to make sense of them. Sure, your “I” or identity, your “you”, might be influenced by reason. But at that vital moment, your logical rationality may either choose to take a backseat (disappear and shut up), or when it's really confused and scared, it might just start lying.We know that philosophy is often pretended to be logical and scientific, and it attempts to ascribe these features to us. And of course, we also like to appeal to rationality as a guide so we are not contradictory or culturally estranged. But maybe we aren't actually being rational when we attempt rationality.Our societal championing of logic has led us into these cul de sacs of harm. We're often plagued with bureaucratic inefficiency, the reduction of people into functions, or tools that are abused. Our behavioral economic knowledge is often used for propaganda and manipulation. And of course, if we're left alone in our heads, constructing stories, we become fragile, and racked with insecurity.We can say that the fault stems from “logic” tainted with capitalism or human urges: we just need more logic to fix it. Thankfully, that is slowly happening, but it is an uphill battle because we have made a society based on efficiency and utility. And there's very little incentive to study things that cannot be measured and monetized and made useful. Things like movement without action, deliberation without decision, morality and virtue that isn't for sale.Fortunately, science has progressed and with more sensitive instruments, scientists and neuro-physicists are now investigating these discarded phenomena, such as “the instinct that saves lives” or the “moment of choice.” This draws them back from this edge, this kind of superstitious hocus-pocus area into more valid concepts.However, the research shows that there really isn't anything that looks like thought on fMRI machines whenever we're deliberating a big decision, which leads us to reconsider what's happening at the “moment of choice.”Some options:1. You can declare your will acted of its own accord. This implies that the real you is your unthinking “will” -your inner urges- and it's enacting your morality or values. But it's definitely not beholden to reason, because your reason just disappeared during the moment of choice. So this means the real you is irrational.2. Through embodied cognition, your body made the decision. And we can call this an instinct. Once again, this is kind of irrational from a classical understanding of reason, or logic.3. You might take this left brain, right brain discussion, and consider a different conclusion: That a more holistic nonlanguage, part of you is weighing in. The Master might actually be taking over from the Emissary.It's not that this part cannot be fooled or be wrong. It is, after all, evolutionarily adapted to maybe a savannah and not really a dense urban population where there's a lot of driving while on cell phones. And of course, they didn't have a whole lot of banana peels on sidewalks back then.But perhaps we have let the little demon between our ears maybe he's been doing too much driving. Perhaps we have not actually set ourselves up for mastery and flow, which is bodily and right brain. Let's consider integrating some other forms of knowledge: use your embodied perception, use your whole self. Sure, keep your reason but supplement it with the rest of your being, expand your cognition through your body, and get to know the right brain version of yourself.This may actually end up expanding who you are and how you relate to the world. And at the same time, it might ground you in a richer reality than your illusory mental models can ever devise.(This is part four of several episodes on “The World Beyond Your Head”) 

This episode is a masterclass in what it takes to be a great student, communicator, leader and marketer.  My guest on the show today is Dr Matt Hill. Matt has been working with Tony Ebel for the past 6 years and Tony told me leading up to this interview that on many days Matt is his favourite person in the world. In this episode we talk about what it takes to form strong and lasting relationships between a principle and an associate. We talk about the importance of listening in communication and Matt shares the marketing strategy that's helping them to reach more families right now. Links: Website: www.thepediatricexperience.com                https://pxdocs.com Instagram: https://www.instagram.com/drmatt_px Bio: Dr Matt and his wife Crystal just celebrated 14 years of marriage and with 4 boys between the ages of 3 and 12 life is busy, loud and fun! Originally from the great state of Arizona, Dr Matt found his calling into Chiropractic after his son, Micah, was born with Agenesis of the Corpus Callosum. After 6 months of struggle and going to specialist after specialist, Matt and Crystal found a pediatric chiropractor who changed their life and Micah's long term health trajectory!  3 years later Dr Matt made a bold decision and left a position in the corporate world to attend Chiropractic school at Palmer in Davenport, Iowa. Getting into Chiropractic for the pediatric and special needs population specifically, made Dr Matt's decision on where and how to practice simple. He has practiced for the last 5+ year in Crystal Lake, IL at PWC Chiropractic with a team specifically focused on helping the toughest pediatric cases not only locally, but helping families that travel to for care from across the US.  In 2020, Dr Matt joined Dr Tony Ebel, who he practices alongside, as a lead clinical guide for The Pediatric Experience. A training community with the sole purpose of training and equipping 1000's of certain, skilled and wildly impactful Pediatric, Prenatal and Family Chiropractors and teams.  See omnystudio.com/listener for privacy information.

The Corpus Callosum. Surviving WW3 lesson 1: For the Urbanite [mapsoc.org for complete notes]. Mailbag featuring Duke of Alba and Two Cycle. With apologies to the MPC Forum. (01:13:00) Interview with Ron Dart about C.S. Lewis and the Christian Ashram movement.LINKS: Fixing Your FeetSmokestack's ShoesSmokestack's SocksRon DartMAPSOC.ORGSumo's SubstackThe Saint Nicholas ProjectFollow us on Twitter: Sumo / Smokestack

A tantrum is an emotional outburst, usually associated with those in emotional distress, that is typically characterized by stubbornness, crying, screaming. What happens when

Dr. Sonika Agarwal of Children's Hospital of Philadelphia talks about Agenesis of the Corpus Callosum.

In this Bingecast episode, Dr. Robert J. Marks and Dr. Michael Egnor explore the human brain and its relationship to the mind. Is the mind an emergent property of the brain? Is there neurological evidence for the soul? What have brain experiments taught us about free will and the human person? Can you still think in a coma? Show Notes… Source

In this Bingecast episode, Dr. Robert J. Marks and Dr. Michael Egnor explore the human brain and its relationship to the mind. Is the mind an emergent property of the brain? Is there neurological evidence for the soul? What have brain experiments taught us about free will and the human person? Can you still think in a coma? Show Notes… Source

Healing Through Encounter April 9, 2021 This is part three of the training that Shanna and Susan taught. In this session we discuss basic brain science. Podcast Highlights: - What is Brain Science? - Right Hemisphere - processes surroundings and draws conclusions - Left Hemisphere - Runs at the speed of words, a verbal processor - Your right brain is where your memories are stored and the left side is where arguments are made - Reticular Activating System: A bundle of nerves at our brain stem that filters out unnecessary information so the important information gets through - Our belief systems are created through our individual experiences - Corpus Callosum: acts as a bridge joining the two sides of the brain together - Psalm 139 - The Control Center holds the Big 6 Emotions you are born with: Anger, Fear, Sadness, Disgust, Shame, and Hopeless Despair - Joy is built up through relationships - You can only process the amount of trauma you have at the level you have JOY in your life - Isaiah 61 Get signed up for the next event HERE Join in the conversation through Facebook The Undivided Heart   

Imagine your hand having a mind of it's own, doing whatever it wants whenever it wants. This is real life for some people suffering from Alien Hand Syndrome. Today we look at the first reported case of Alien Hand Syndrome and how changes to your brain create this alien visitor.If you have a question you want us to research, send an email to Factschology@gmail.comAnd if you like the show, give us a rating, leave a review, or subscribe!Sourceshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059570https://www.healthline.com/health/alien-hand-syndromehttps://n.neurology.org/content/91/11/527https://onlinelibrary.wiley.com/doi/full/10.1002/ccr3.3166https://www.medlink.com/article/alien_hand_syndromehttps://www.neurologylive.com/view/alien-hand-syndromehttps://www.neuroscientificallychallenged.com/blog/know-your-brain-corpus-callosumhttps://youthneuro.org/journal/article/99/Support the show (https://www.patreon.com/Factschology)

The first She Words Podcast reflects on creating a "Bucket List or Live List." As a mother of three children and one exceptional needs, confusion and uncertainty regarding our son's future pulled me into understanding the importance of living for today. Our son was born with Agenesis of the Corpus Callosum in 2001, and we were told he may not live long or if he did it would be with many limitations and possible deformities. We were scared, confused, hurt, and saddened. Today he is 19 years old and we are excited, happy, driven, and peaceful. How? Because as a family we decided to LIVE!Are you living life to the best of your ability? Do you wake up excited and ready to embrace each new day? In this podcast, I discuss what happens when one organizes your dreams, goals, and wishes into creating a "Bucket List or Live List" for you and your family. Our son Jeremiah opened my eyes to understanding how to enjoy the journey of life. Each small accomplishment is a step in the right direction. I know how to make a glass of lemonade out of lemons, how to see my glass as half full and not half empty, and how to lay down in peace at night knowing I did not waste a moment of this precious life given to me. Take a moment to listen and learn, the importance of creating a LIVE LIST. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The corpus callosum links one side of our brain to the other. It’s not essential for survival, but in some people it’s missing or malformed, causing quite mild to extreme disabilities. The good news is that research is now revealing that it holds intriguing secrets about brain plasticity. This program was first broadcast in May 2016.

The corpus callosum links one side of our brain to the other. It’s not essential for survival, but in some people it’s missing or malformed, causing quite mild to extreme disabilities. The good news is that research is now revealing that it holds intriguing secrets about brain plasticity. This program was first broadcast in May 2016.

Have you ever lost a loved one who was still a part of your life in some way? Did it leave you feeling confused or frozen about how to continue with life? Claudia Hammond examines the distressing phenomenon known as ambiguous loss – the enormous challenge of dealing with a loss when you aren’t sure what’s happened, leaving you searching for answers, unable to move on. The All in the Mind 2021 mental health awards have just been launched, where you can nominate the person or group who has a made a difference to your mental health. Claudia catches up with some of the finalists from the past to see what’s happened to them since, and what the awards have meant for them. What has the pandemic done to our memories? Anecdotally many report they keep forgetting things they’re sure they would have remembered before. Claudia’s studio guest, Professor Catherine Loveday of the University of Westminster examines the new emerging evidence behind this phenomenon. Our brains are in two halves and they are linked by a structure known as the corpus callosum. But some babies are born without a corpus callosum linking the brain's two sides. A quarter of these babies grow up with serious developmental difficulties, while others have no difficulties at all, suggesting that somehow the brain is compensating. A researcher at the University of Geneva. Dr Vanessa See-freddi, has scanned the brains of children aged between 8 and 17 and has found that for some children the two halves of their brains succeed in communicating. Producer Adrian Washbourne

Nic’s doctor warns him that his brain is changing in strange ways, but it doesn’t stop him from heading back up to Northern British Columbia with a renewed sense of purpose. We finally hear from Rose Hempel herself, which makes Nic even more determined to find out what really happened to her inside the area of the woods known as The Garrison Anomaly.  

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.15.252205v1?rss=1 Authors: Westerhausen, R., Fjell, A. M., Kompus, K., Steven, S. J., Sherwood, C., Walhovd, K. B., Hopkins, W. D. Abstract: The human corpus callosum exhibits substantial atrophy in old age, which is stronger than what would be predicted from parallel changes in overall brain anatomy. To date, however, it has not been conclusively established whether this accentuated decline represents a common feature of brain aging across species, or whether it is a specific characteristic of the aging human brain. In the present cross-sectional study, we address this question by comparing age-related difference in corpus callosum morphology of chimpanzees and humans. For this purpose, we measured total midsagittal area and regional thickness of the corpus callosum from T1-weighted MRI data from 213 chimpanzees, aged between 9 and 54 years. The results were compared with data drawn from a large-scale human samples which was age-range matched using two strategies: (a) matching by chronological age (human sample size: n = 562), or (b) matching by accounting for differences in longevity and various maturational events between the species (i.e., adjusted human age range: 13.6 to 80.9 years; n = 664). Using generalized additive modelling to fit and compare aging trajectories, we found significant differences between the two species. The chimpanzee aging trajectory compared to the human trajectory was characterized by a slower increase from adolescence to middle adulthood, and by a lack of substantial decline from middle to old adulthood, which, however, was present in humans. Thus, the accentuated decline of the corpus callosum found in aging humans, is not an universal characteristic of the aging brain, and appears to be human-specific. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.03.233593v1?rss=1 Authors: Morcom, L., Gobius, I., Marsh, A. P. L., Suarez, R., Bridges, C., Ye, Y., Fenlon, L., Zagar, Y., Douglas, A. M., Donahoo, A.-L., Fothergill, T., Shaikh, S., Kozulin, P., Edwards, T. J., Cooper, H. M., ,, Sherr, E. H., Chedotal, A., Leventer, R., Lockhart, P., Richards, L. J. Abstract: The forebrain hemispheres are predominantly separated during embryogenesis by the interhemispheric fissure (IHF). Radial astroglia remodel the IHF to form a continuous substrate between the hemispheres for midline crossing of the corpus callosum (CC) and hippocampal commissure (HC). DCC and NTN1 are molecules that have an evolutionarily conserved function in commissural axon guidance. The CC and HC are absent in Dcc and Ntn1 knockout mice, while other commissures are only partially affected, suggesting an additional aetiology in forebrain commissure formation. Here, we find that these molecules play a critical role in regulating astroglial development and IHF remodelling during CC and HC formation. Human subjects with DCC mutations display disrupted IHF remodelling associated with CC and HC malformations. Thus, axon guidance molecules such as DCC and NTN1 first regulate the formation of a midline substrate for dorsal commissures prior to their role in regulating axonal growth and guidance across it. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.29.227827v1?rss=1 Authors: Morcom, L., Edwards, T. J., Rider, E., Jones-Davis, D., Lim, J. W., Chen, K.-S., Dean, R., Bunt, J., Ye, Y., Gobius, I., Suarez, R., Mandelstam, S., Sherr, E. H., Richards, L. J. Abstract: Corpus callosum dysgenesis (CCD) is a congenital disorder that incorporates either partial or complete absence of the largest cerebral commissure. Remodelling of the interhemispheric fissure (IHF) provides a substrate for callosal axons to cross between hemispheres, and its failure is the main cause of complete CCD. However, it is unclear whether defects in this process could give rise to the heterogeneity of expressivity and phenotypes seen in human cases of CCD. We identify incomplete IHF remodelling as the key structural correlate for the range of callosal abnormalities in inbred and outcrossed BTBR mouse strains, as well as in humans with partial CCD. We identify an eight base pair deletion in Draxin and misregulated astroglial and leptomeningeal proliferation as genetic and cellular factors for variable IHF remodelling and CCD in BTBR acallosal strains. These findings support a model where genetic events determine corpus callosum structure by influencing leptomeningeal-astroglial interactions at the IHF. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.12.148569v1?rss=1 Authors: Lee, H. I., Cho, M., Na, Y., Hwang, Y. M., Pyun, S.-B. Abstract: Background The corpus callosum (CC) serves as the bridge that relays information between the two cerebral hemispheres, and is one of the most commonly injured areas after traumatic brain injury (TBI). This study was designed to investigate the association between the CC integrity and language function after TBI. Methods We retrospectively enrolled 30 patients with TBI who underwent diffusion tensor imaging and language function evaluation using the Western Aphasia Battery. The CC was divided into five segments (C1-C5) according to its projecting fibers using Hofers method, and fractional anisotropy (FA) values were measured using DSI studio software. The FA values of the left arcuate fasciculus and cingulum for language function and executive function, respectively, were also evaluated. Twelve healthy controls were also enrolled to compare the FA values of these tracts. Results The FA values of the cingulum and left arcuate fasciculus were significantly correlated with all language scores. The FA values of the entire CC were significantly correlated with the fluency, repetition, and aphasia quotient scores. The FA values of the anterior CC segment (C1 and C2) significantly correlated with the aphasia quotient score; C1 with the fluency score; and C2 with the fluency, comprehension, and repetition scores. However, the FA values of the posterior CC (C3-C5) were not significantly correlated with any of the language subset scores. Conclusion The language function in patients with TBI is correlated with the integrity of the white matter tracts important for language and attention processes. Moreover, disruption of the CC is common after TBI, and the anterior CC segment plays an important role in language impairment after TBI. Therefore, analyzing CC integrity using diffusion tensor imaging can help predict language impairment in patients with TBI. Copy rights belong to original authors. Visit the link for more info

In der letzten Folge hatten wir uns mit Splitbrain beschäftigt und uns am Ende die Frage gestellt: Was ist, wenn die Verbindung zwischen den Gehirnhälften, das Corpus Callosum oder der "Balken", nicht operativ durchtrennt wird, sondern von Geburt an nicht vorhanden ist? In dieser Folge gehen wir der Frage nach und schauen, wie sich das Gehirn an einen angeborenen Balkenmangel gewöhnen und ihn kompensieren kann. Als Quellen dienten uns: 1) ein Lehrbuch: Ocklenburg, S., & Gunturkun, O. (2017). The lateralized brain: The neuroscience and evolution of hemispheric asymmetries. Academic Press., 2) der Finder des Probst-Bündels: https://de.wikipedia.org/wiki/Probst-B%C3%BCndel; 3) Definitionen: Spektrum Verlag – Lexikon der Neurowissenschaft: „Balkenagenesie“ https://www.spektrum.de/lexikon/neurowissenschaft/balkenagenesie/1246 und „Plastizität“ https://www.spektrum.de/lexikon/neurowissenschaft/plastizitaet-im-nervensystem/9979; 4) das Forschungsprogramm: Corpus Callosum Disorders Research Program der Caltech: http://emotion.caltech.edu/research/agcc/; 5) der Übersichtsartikel: Brown, Warren S. and Paul, Lynn K. (2019) The Neuropsychological Syndrome of Agenesis of the Corpus Callosum. Journal of the International Neuropsychological Society, 25 (3). pp. 324-330. ISSN 1355-6177. https://resolver.caltech.edu/CaltechAUTHORS:20190311-142733872

Part 1: Zach, Michael and Andrew discuss movies they saw this week, including: Emma., Dark Waters, Portrait of a Lady on Fire and The Mosquito Coast.Part 2 (35:33): The group continues their Intro to Avant-Garde series with a selection of feature films from director Michael Snow –– 1967's Wavelength and 2002's *Corpus Callosum.See movies discussed in this episode here.Film list for the Intro to Avant-Garde series.Also follow us on: Facebook Twitter Letterboxd Spotify Stitcher Radio Radio Public ★ Support this podcast on Patreon ★

If you lose all four of your limbs, are you still you? Most people would say yes. What if your brain were cut into two pieces? Would you still be you? Robert J. Marks and Dr. Michael Egnor discuss splitting the brain and the research of Roger Sperry. Show Notes 00:30 | Introducing Dr. Michael Egnor, Professor of Neurosurgery and… Source

If you lose all four of your limbs, are you still you? Most people would say yes. What if your brain were cut into two pieces? Would you still be you? Robert J. Marks and Dr. Michael Egnor discuss splitting the brain and the research of Roger Sperry. Show Notes 00:30 | Introducing Dr. Michael Egnor, Professor of Neurosurgery and Read More › Source

This week on the Method Section, Tom explains the process of writing a scientific paper. Something that he has much experience with at an academic level he now invites you to join him on the beginning of his journey of his MSc. thesis in the neuroscience of marine mammals. In the latter half of the show Tom reviews his favourite part of the brain so far, the Corpus Callosum, and why it is so. Music by: Joakim Karud - https://soundcloud.com/joakimkarud.

A victim of the incredibly rare ‘Agenesis of the Corpus Callosum,’ Derek was once able to do most normal, everyday activities. Until he wasn’t. As a then 14-year-old, complaints of a headache soon meant Derek would never speak, eat, or perform standard daily functions again. Derek’s mother joins us, detailing the regression of her son’s condition, and how she, as his dedicated caretaker, has managed to get through each new day rebuilding her beloved son. Tune in today to watch this special episode on YouTube, and learn all about the Lyons’ story.   For The Hayters YouTube Channel Check out our website and share your story! forthehayters.com Follow us on Instagram, Twitter and Facebook! @forthehayters Buy some merch! forthehayters.com/the-shop

Link : I would love for you to join the Corpus Callosum community. https://www.facebook.com/groups/260853604466712/ *** BE CREATIVE. BE INSPIRED. BE YOU.

How can you use yellow filters to add something different to your shots? *** Link : I would love for you to join the Corpus Callosum community. https://www.facebook.com/groups/260853604466712/ *** BE CREATIVE. BE INSPIRED. BE YOU.

Complementary Metal Oxide Semiconductor. But what is it. I explain exactly this in this episode. *** Link : I would love for you to join the Corpus Callosum community. https://www.facebook.com/groups/260853604466712/ *** BE CREATIVE. BE INSPIRED. BE YOU.

Explaining how this photoshop editing technique can be used to create a realistic blend. *** Link : I would love for you to join the Corpus Callosum community. https://www.facebook.com/groups/260853604466712/ *** BE CREATIVE. BE INSPIRED. BE YOU.

Like a parent neglecting his over-achieving daughter and his obviously at-risk son, Bill is once more stuck at work, leaving Jay and Jessica to once again keep the podcast flame burning without him.  This week, helping them do so is the vivacious TV personality, Anna Lacy  The discussion runs the gamut from male/female brain structure, to the Find My Friends App on the iPhone, to Anna's participation in the TV Show that Bill and Jay are producing through their new company!  You won't want to miss it! Special thanks to our Sponsors: Vinnie Brand, owner of the Stress Factory Comedy Club Steve Kalafer, owner of Flemington Car & Truck and the Somerset Patriots. Rob Dekanski from Re/Max 1st Advantage.  Call Rob at 855-350-1015! Peter Greco from the CSI Group.  Call 1-800-TAX-LAWS! Tito's Handmade Vodka Remember to subscribe, rate, and review us in iTunes!

Request access; https://m.facebook.com/groups/260853604466712 This closed Facebook group has been created in order to bring creators together, for us to share ideas, showcase our work, collaborate, ask questions and learn from one another, discuss concepts and ideas and to refer work between us as a community. Whilst the group is open to all creatives, it is a closed group and therefore access is by invitation and request only. Feel free to invite creators who you know, but examples of their work will be required prior to acceptance. I know this may sound harsh, but the concept behind the group is to be different from the other groups on Facebook. What this group is not, is a place where negativity will be tolerated. Constructive criticism is always welcome, but this is a space that promotes positivity. We’re in this together, and I'd love for you and all creators to join the community. Request access; https://m.facebook.com/groups/260853604466712

Wer sich positionieren will, benötigt, heute mehr denn je zuvor, eine glaubwürdige Identität. Glaubwürdigkeit bedeutet: Nachvollziehbarkeit, Zuverlässigkeit, Wahrhaftigkeit, Ehrlichkeit – und viele Tugenden mehr. Doch Obacht! Glaubwürdigkeit ist ein zweischneidiges Schwert. Und wer es nur als Tugendbündel interpretiert, richtet das Schwert vor allem gegen sich selbst, auch weil zu viel Altruismus zur Selbstausbeutung führt.   Damit ist schon skizziert, dass es sich bei der Glaubwürdigkeit keineswegs um eine bedenkenlose Zurschaustellung von Tugenden handelt. Wer sich nur selbstlos und altruistisch gibt, hat zwar Chancen, zum Heiligen erklärt zu werden, macht aber eher einen naiven und dämlichen Eindruck. Und das ist äußerst kontraproduktiv vor allem dann, wenn man sich im schwierigen Wettbewerb um die besten Jobs befindet. Die brauchen Leute, die auch mal kräftig zubeißen können. Keine Firma wird freiwillig einen immer lächelnden Depp einstellen.   Spaß beiseite: Wer zu selbstlos ist, kann schon bald sein Selbst los sein. Wer selbst zur Marke werden will, muss deshalb lernen, zu sich selbst zu stehen. Zu sich selbst zu stehen heißt: Ganz zu sein. Sich selbst gegenüber hundertprozentig ehrlich zu sein. Und nach außen hin auf eine intelligente Art diplomatisch. Für die heute so entscheidende glaubwürdige Kommunikation gilt deshalb die Devise: Wahrhaftigkeit bin ich vor allem mir selbst schuldig. Nach außen hin gilt es, eindeutig unzweideutig und beständig zu sein, aber Unhöflichkeiten zu meiden. Also aller Wahrhaftigkeit zum Trotz den guten Ton zu wahren. Das ist manchmal gar nicht so einfach.   Notwendig ist ein gutes Selbst- und Identitätsmanagement, das beide Auflagen erfüllt: Dem eigenen Ego zu dienen und einen guten Umgangston zu pflegen. Und trotzdem authentisch zu sein. Nicht nur, dass das funktioniert – es ist sogar die einzige Möglichkeit. Es ist nämlich vollkommen normal und gesund, an sich zu denken, wenn es um die Karriere geht. Dazu gehört aber, ebenfalls aus Egoismus, ein gutes Benehmen.   Beides zusammen ergibt das „Königsmerkmal“ eines guten Kommunikators. Authentizität steht in der Rangliste der gekonnten Kommunikation an erster Stelle, und es ist, wie die bisherigen Ausführungen belegen, eine Kunst.   Authentizität ist das „Missing Link“ zwischen dem Selbst einer Person und dessen Identität. Sie ist, so könnte man auch sagen, das „Corpus Callosum“ zwischen Identität und Selbst. Das Corpus Callosum ist derjenige Teil des Gehirns, der die linke mit der rechten Hälfte verbindet und für die Koordination von Emotion und Kognition zuständig ist.   Authentisch kommunizieren heißt aktiv gestalten.   Ist die nach außen getragene Identität aufgrund gesellschaftlicher und kultureller Einflussgrößen wie Sitten, Traditionen Gepflogenheiten und als kommunikativer, diplomatischer Teil der Persona in großen Teilen gestaltbar, so weist das Selbst als Produkt angeborener Prädispositionen und unbewusst von außen übernommener Prägungen eine viel größere Zähigkeit auf. Zum Selbst gehören nämlich auch die Instinktsphäre und der Selbsterhaltungstrieb.   Kernstück der authentischen Identität als auch nonverbal kommunizierender Teil der Persönlichkeitsorganisation ist jene möglichst weitgehende „Passgenauigkeit“ bzw. Kongruenz von Selbst und Identität. Es geht eben um beides: Innen und außen. Dafür besitzen wir ein bewusstes Ich.   Und es geht um ein Gleichgewicht von „maximaler“ und „optimaler“ Authentizität. Sich selbst gegenüber sollte man schon das Maximum anstreben. Anderen Menschen gegenüber ist jedoch ein situationsgerechtes Vorgehen zu empfehlen … aber das versteht sich ja eigentlich von selbst.   Die Kunst, authentisch zu sein (und nicht nur authentisch zu wirken) geht also zwingendSupport the show (https://www.paypal.com/cgi-bin/webscr?cmd=_s-xclick&hosted_button_id=2PU5W9H752VZJ&source=url)

Co-hosts, Kendall Heath and Debbie Chisholm, interview Andy Silver today from our podcasting table that he nicknamed "The Corpus Callosum" for its job of giving everyone a place to communicated between both hemispheres of the brain. (We loved it!)  A constant comedian, Andy Silver, "Spiritual Mediator in the Field", has been working in the healing/spiritual community much longer than social media and podcasts have been around, and he's got a historical archive inside of him to proove it! Once a reluctant, young member of The Peoples Temple Agricultural Project, better known as "Jonestown", and one of 20 who did not travel on the Guyana trip that resulted in the deaths of more than 900 people in the Jonestown Massacre, Andy moved on to work in the fields of Neuro Linguistic Programming, Conflict Resolution & Divorce Meditation, Hypnosis, and ultimately Intuitive Medium work.  On today's show he talks about his spiritual and vocational journey that spans several decades, including extensive training in The Silva Method, mediation work for Fema after Hurricane Katrina, over 3700 psychic medium readings, and his passion for stand-up comedy. Andy also shares some of the tools he's gathered along the way for spiritual self-care and balance, and talks a little about "the old days" and some of the early key voices in the Charlotte spiritual community.  Dive into the treasure chest that is one of our spiritual community elders here in Charlotte/Lake Norman, Andy Silver. Learn more about Andy at www.ResolutionExperts.com and www.AndySilver.us Learn more about Spiritual Charlotte at www.lighthousespiritualcenter.com    

Co-hosts, Kendall Heath and Debbie Chisholm, interview Andy Silver today from our podcasting table that he nicknamed "The Corpus Callosum" for its job of giving everyone a place to communicated between both hemispheres of the brain. (We loved it!)  A constant comedian, Andy Silver, "Spiritual Mediator in the Field", has been working in the healing/spiritual community much longer than social media and podcasts have been around, and he's got a historical archive inside of him to proove it! Once a reluctant, young member of The Peoples Temple Agricultural Project, better known as "Jonestown", and one of 20 who did not travel on the Guyana trip that resulted in the deaths of more than 900 people in the Jonestown Massacre, Andy moved on to work in the fields of Neuro Linguistic Programming, Conflict Resolution & Divorce Meditation, Hypnosis, and ultimately Intuitive Medium work. On today's show he talks about his spiritual and vocational journey that spans several decades, including extensive training in The Silva Method, mediation work for Fema after Hurricane Katrina, over 3700 psychic medium readings, and his passion for stand-up comedy. Andy also shares some of the tools he's gathered along the way for spiritual self-care and balance, and talks a little about "the old days" and some of the early key voices in the Charlotte spiritual community. Dive into the treasure chest that is one of our spiritual community elders here in Charlotte/Lake Norman, Andy Silver. Learn more about Andy at www.ResolutionExperts.com and www.AndySilver.us Learn more about Spiritual Charlotte at www.lighthousespiritualcenter.com  

- Brain metabolism (sugar, lactate, and ketones) - Frontal lobe (Phineas Gage getting a rod through his head, motor cortex, dementia, and Broca's aphasia - inability to create words) - Parietal lobe (Sensory cortex, phantom limb, neuroplasticity, disowning your own body parts) - Temporal lobe (memory, learning, epilepsy and religious experiences, Wernicke's aphasia - word-salad) - Occpital lobe (interpreting vision, visual disorders) - Insula (food avoidance after food poisoning) - Corpus Callosum (Split brain experiment, separating consciousness, confabulation) - Cerebellum (proprioception, balance, cerebral ataxia, walking on all four limbs, getting drunk)

Ever have trouble deciding between your scientific side and your creative side? Corpus Callosum is the answer! This episode we sat down with Lili and Megan who are both heavily involved in Corpus Callosum (CoCa), an organization that combines engineering and art. They share with us some cool important projects they have done, the structure of their group, and the importance of embracing both sides of the brain!

Topics Discussed: Fires Around the Area, Happy Fourth Birthday WHGL!, Dub Takes in a Show in Missoula, One Bluegrass Song, Diet Check-In Lite, Retractions and Addendums, Revisiting the Corpus Callosum, a Misinterpreted Cupcake Joke, a Dog De-gloves a Man, Word of the Day, Dub Deals with a Traffic Accident, Balancing the Moral Dilemma of Eating Meat but Hating the Process, Vegans are Annoying, A Key Marketing Component in an Evil Industry, Man Locks Himself in the most Spacious Trunk Ever, Strangers Falling Asleep in your Unlocked Car, Utilizing the Element of Surprise, Seinfeld's an Unfunny but Successful Creep, Talking to Teens is the Worst, the Tragic Realization that Nobody Knows Anything, Pugs on Shelves, and the Diet Feels Good!  

Das Corpus Callosum stellt für motorische Entwicklung eine Schlüsselstruktur dar. In der klinischen Routine werden spiegelbildliche Mitbewegungen häufig als Indikator kindlicher motorischer Entwicklung herangezogen. Die zugrundeliegenden neuronalen Reifungsprozesse können mit einer komplementären Methodenkombination aus transcranieller Magnetstimulation (TMS) und Diffusionstensorbildgebung (MR-DTI) untersucht werden. Die TMS bildet dabei die inhibitorische Kompetenz des Cortex ab, wohingegen die MR-DTI die Darstellung und Quantifizierung der Mikrostruktur von neuronalen Verbindungen ermöglicht. Ziel dieser Arbeit war es, motorische Entwicklung klinisch, neurophysiologisch und strukturell zu untersuchen und einen potentiellen, objektiv-quantifizierbaren Surrogatmarker für motorische Entwicklung zu identifizieren. Wir untersuchten 31 gesunde Rechtshänder: 11 Kinder, 10 Jugendliche und 10 Erwachsene. Zur computergestützten Untersuchung spiegelbildlicher Mitbewegungen wurden isometrische Kräfte bei unimanuellen, repetitiven (langsamen und schnellen) Kraftwechseln aufgezeichnet und der Spiegelquotient (SQ) berechnet. Mit der neuronavigiert durchgeführten TMS wurden Dauer, Latenz und Fläche der ipsilateralen silent period (iSP) bestimmt. Mithilfe der MR-DTI wurde die fraktionierte Anisotropie (FA) in den Arealen I-V des Corpus Callosum quantifiziert. Der Spiegelquotient ist bei Kindern signifikant höher als bei Jugendlichen und Erwachsenen. In geringem Ausmaß weisen aber auch diese zwei Gruppen noch spiegelbildliche Mitbewegungen auf. Bei den TMS Parametern zeigt sich im Altersverlauf ein Anstieg von Dauer und Fläche der iSP. Jugendliche unterscheiden sich dabei allerdings nicht mehr signifikant von Erwachsenen. Die FA der Area III, in der die motorischen Fasern kreuzen, ist bei Kindern signifikant kleiner als bei Jugendlichen und Erwachsenen. Zusätzlich ergibt sich eine niedrigere FA bei Jugendlichen im Vergleich zu Erwachsenen. Es zeigt sich ein starker Zusammenhang über alle Gruppen hinweg zwischen FA in Area III und Handmotorik bzw. iSP. Weniger eindrücklich aber dennoch vorhanden ist die Korrelation zwischen iSP und Handmotorik. Das Ausmaß spiegelbildlicher Mitbewegungen ist konsistent mit der Mikrostruktur transcallosal verlaufender motorischer Bahnen und dem Grad der inhibitorischen Kompetenz. Dabei detektiert die MR-DTI als einzige der drei angewandten Methoden selbst kleinste Unterschiede motorischer Funktion zwischen Jugendlichen und Erwachsenen, die klinisch nicht mehr apparent sind. Die Anisotropie motorischer transcallosaler Bahnen der Area III könnte damit ein potentieller, objektiv quantifizierbarer Marker für motorische Entwicklung sein. Weitere Untersuchungen werden zeigen, ob sich mit der in dieser Arbeit etablierten Methodenkombination Norm von Pathologie differenzieren lassen.

Thu, 12 Feb 2009 12:00:00 +0100 https://edoc.ub.uni-muenchen.de/9666/ https://edoc.ub.uni-muenchen.de/9666/1/Moeller_Tobias.pdf Möller, Tobias

Dr Mark Walterfang is a psychiatrist based at the Neuropsychiatry Centre, University of Melbourne. Together with some co-authors, Dr Walterfang has published a paper in the June issue of the British Journal of Psychiatry on morphology of the corpus callosum at different stages of schizophrenia: cross-sectional study in first-episode and chronic illness. He discusses his paper here with Raj Persaud.

Thu, 15 Nov 2007 12:00:00 +0100 https://edoc.ub.uni-muenchen.de/7687/ https://edoc.ub.uni-muenchen.de/7687/1/Hoehne_Christian.pdf Hoehne, Christian

Zahlreiche Befunde deuten auf eine Störung der interhemisphärischen Konnektivität bei Patienten mit Schizophrenie. Funktionell wurden beispielsweise Veränderungen der interhemisphärischen Kohärenz gefunden. Die Kohärenz gilt als ein Indikator für funktionelle Verbindungen zwischen den entsprechenden Hirnregionen und ist in ihrer interhemisphärischen Variante ein Maß für die Synchronisation des EEG zwischen den korrespondierenden bilateralen Regionen. Für die interhemisphärische Kohärenz und die interhemisphärische Konnektivität kommt dem Corpus Callosum (CC) als wichtigster kommissuraler Verbindung der Hemisphären eine entscheidende Bedeutung zu. Gleichzeitig ist bei CC-Pathologien einerseits die Prävalenz der Schizophrenie erhöht und es findet sich andererseits bei Patienten mit Schizophrenie ein erhöhtes Vorkommen von CC-Pathologien. Strukturelle MRT-Befunde deuten auf ein leicht verkleinertes CC bei Patienten mit Schizophrenie. Zusätzlich finden sich pathologische Veränderungen in der Lamina III des präfrontalen Kortex von Patienten mit Schizophrenie, dem Ursprungsort der kallosalen Projektionen. Auch Entwicklungshypothesen finden Bezug zu einer Pathologie des CC bei Patienten mit Schizophrenie: seine Entwicklung, bei der die Elimination von Axonen mit zunehmender Myelinisierung und Vergrößerung einhergeht, zieht sich bis in die dritte Lebensdekade hin und zeigt damit Parallelen zur späten klinischen Manifestation der Erkrankung. Aufgrund der Heterogenität der Befunde ist allerdings nicht klar, welcher Art die Störung der interhemisphärischen Konnektivität bei Patienten mit Schizophrenie ist. Eine Hypokonnektivität würde z.B. die Assoziation zwischen CC-Agenesien und Schizophrenie vermuten lassen, neuro- und psychophysiologische Experimente deuten eher in Richtung einer Hyperkonnektivität. Ziel der Arbeit war die explorative Untersuchung der Frage, ob eine Störung der interhemisphärischen Konnektivität bei Patienten mit Schizophrenie vorliegt und welcher Art diese interhemisphärische Konnektivitätsstörung sein könnte. Methode: Es wurden 27 männliche Patienten mit chronischer Schizophrenie und 25 gematchte Kontrollen untersucht. Anhand des Ruhe-EEGs wurden fünf interhemisphärische Kohärenzen bipolarer Verschaltungen berechnet. Mittels MRT wurde die CC-Größe durch Vermessung der midsagittalen Fläche des CC ermittelt und in fünf Unterabschnitte unterteilt. Neben der Analyse auf Unterschiede bezüglich der Kohärenzen und der CC-Größe, wurden die interhemisphärischen Kohärenzen mit der CC-Größe korreliert, um über die Verbindung von strukturellen und funktionellen Parametern Hinweise über die Integrität der interhemisphärischen Konnektivität zu erhalten. Zusätzlich wurde der Einfluss der neuroleptischen Medikation und die Abhängigkeit der Kohärenzen und der CC-Größe von klinischen Parametern anhand der PANSS-Skala untersucht. Ergebnisse: Die Mittelwerte frontozentraler interhemisphärischer Kohärenzen waren im Beta-Frequenzbereich signifikant bei den Patienten mit Schizophrenie gegenüber den Kontrollpersonen erhöht. Dabei zeigte sich eine negative Korrelation zwischen der Neuroleptika-Dosis und der Höhe der Kohärenzen. Für die CC-Größe zeigten sich keine signifikanten Unterschiede. Klinisch korrelierten frontale und frontotemporale Theta-Kohärenzen mit der Psychopathologischen Globalskala, aber nicht mit der Positiv- oder Negativsymptomatik. Die Pearson-Korrelationen der interhemisphärischen Kohärenzen mit der CC-Größe zeigten bei den Patienten für alle Frequenzbereiche signifikant positive Korrelationen zwischen den interhemisphärischen Kohärenzen besonders in mittleren Segmenten des CC. Nach Berücksichtigung des Neuroleptika-Einflusses waren diese Korrelationen noch deutlicher. Dagegen wiesen die Gesunden negative Korrelationen zwischen allen interhemisphärischen Kohärenzen im Delta- und Beta-Frequenzbereich ebenfalls besonders in mittleren CC-Segmenten auf. Diskussion: Damit bestehen Hinweise für eine interhemisphärische Hyperkonnektivität bei Patienten mit Schizophrenie. Während bei Gesunden mit steigender CC-Größe die interhemisphärische Konnektivität abnimmt, nimmt sie bei den Patienten mit Schizophrenie zu. Im Rahmen einer Entwicklungshypothese mit gestörter kallosaler Entwicklung könnte die in der Literatur gefundene Tendenz einer CC-Verkleinerung für eine vermehrte Anzahl an Axonen, mit verminderter Myelinisierung sprechen, da in der kallosalen Entwicklung die Größenzunahme und zunehmende Myelinisierung mit der massiven Elimination von Axonen einhergeht. Eine verminderte Elimination von Axonen könnte somit die Grundlage einer interhemisphärischen Hyperkonnektivität sein. Verkleinerungen von Pyramidenzellen in Lamina III des präfrontalen Kortex, den Ursprüngen der kallosalen Axone scheinen dies zu bestätigen. Auch psychophysiologische Experimente unterstützen eine interhemisphärische Hyperkonnektivitäts-Hypothese. Ähnlich wird sie durch das Modell einer verminderten Lateralisierung bei Patienten mit Schizophrenie unterstützt, welche mit einer Hyperkonnektivität einhergeht. Ein weiterer Aspekt der interhemisphärischen Hyperkonnektivität ist eine verminderte Inhibition auf kortikaler Ebene, welche durch eine Funktionsabschwächung inhibitorischer GABAerger Interneuronen in Lamina III des präfrontalen Kortex erklärt wird. Die GABAergen Interneuronen werden ihrerseits durch dopaminerge Afferenzen inhibiert, welche bei Patienten mit Schizophrenie pathologisch vermehrt sind. Es resultiert daher eine Disinhibition der Pyramidenzellen, den Ursprungsorten kortikaler Projektionen. Neuroleptika als Dopamin-Antagonisten würden damit diese Hyperkonnektivität reduzieren. Die signifikante Korrelation der Kohärenzen mit der globalen Psychopathologie, aber nicht mit den jeweiligen Positiv- oder Negativ-Skalen spricht eher für die Einheit dieser Symptomkonstellationen, unter dem Vollbild der Schizophrenie.