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3 episodes with placebo effects
2 episodes with placebo effects
2 episodes with placebo effects
2 episodes with placebo effects
2 episodes with placebo effects
Send us a textAbout the guest: Joshua Siegel, MD, PhD is a psychiatrist & systems neuroscience at New York University. He uses functional imaging to study the effects of psychedelics and other drugs on the human brain.Episode summary: Nick and Dr. Siegel discuss: fMRI and how it works; relationship between neural activity and blood flow; functional connectivity & the default mode network of the human brain; the functional effects of psilocybin on the brain; the role that subjective & expectancy effects in psychedelics medicine; and more.Related episodes:M&M #173: Psychedelics, Consciousness, Psychiatry, Psychology, Mental Health & the Entropic Brain HypothesisM&M #163: Anesthesia, Placebo Effects, Consciousness, Subjectivity, MDMA, Ketamine, Opioids, Psychedelics*This content is never meant to serve as medical adviceSupport the showAll episodes (audio & video), show notes, transcripts, and more at the M&M Substack Affiliates: MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils, artificial ingredients, etc. Use code MIND for 20% off. SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount. Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL Learn all the ways you can support my efforts
This is a fascinating and complicated dive into the history behind the first placebos and observations of their effects. We'll do our best not to lose our own minds trying to sort out the complexities of the placebo effect as we understood it simply in the past, and try to contrast that with all of the newer science on the topic. This gets weird.Sources:Wikipedia: Placebo https://en.wikipedia.org/wiki/PlaceboThe Neuroscience of Placebo Effects, Nature Reviews (paywall), Wager and Atlas https://www.nature.com/articles/nrn3976The Early History of the Placebo, Jutte (paywall) https://www.sciencedirect.com/science/article/pii/S0965229912000866Attempts to Revive Antient Medical Doctrines, by Alex Sutherland (Google Books), https://www.google.com/books/edition/Attempts_to_Revive_Antient_Medical_Doctr/AntbAAAAQAAJ?hl=en&gbpv=1&pg=PP26&printsec=frontcoverPlacebo etymology, https://www.etymonline.com/word/placeboPodcast: Skeptics with a K -Episode #386 ----- Patreon Page (support the show) -----Submit a Question for Non-Medical Opinions Segment (website form with instructions)-----Podcast Linktree (social media links / reviews / ratings)-----
How do placebo effects work? Guest: Dr. Jeremy Howick, Epidemiologist and Author of “The Power of Placebos” Learn more about your ad choices. Visit megaphone.fm/adchoices
Send us a textAbout the guest: Gregory Scherrer, PharmD, PhD is a neuroscientist whose lab at teh University of North Carolina studies the neural basis of pain, including its sensory, emotional, and cognitive components. Episode summary: Nick and Dr. Scherrer discuss: the neural basis of pain sensation & pain perception; opioids & the opioid system; cognitive modulation of painful experiences; neural basis of placebo effects; endogenous opioid system; and more.Related episodes:M&M #52: Pain Drugs, NSAIDs, Opioids, Oxycodone, Heroin, Fentanyl & the Neuroscience of Pain | David RobersonM&M #159: Neuroscience of Social Behavior, Pain, Empathy, Emotion, Brain Mechanisms of MDMA | Monique Smith*This content is never meant to serve as medical advice.Support the showAll episodes (audio & video), show notes, transcripts, and more at the M&M Substack Affiliates: MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils, artificial ingredients, etc. Use code MIND for 20% off. SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount. Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. Learn all the ways you can support my efforts
Send us a Text Message.About the guest: Robin Carhart-Harris, PhD is a neuroscientist & psychopharmacologist. His lab at the University of California-San Francisco studies the effects of psychedelics and other drugs on the human brain, using neuroimaging and other approaches.Episode summary: Nick and Dr. Carhart-Harris discuss: psychedelics & the human brain; functional connectivity & entropy in brain patterns; the “entropic brain” hypothesis of psychedelic drug action; psychiatry & depression; psychology, Carl Jung & Sigmund Freud; the FDA's rejection of MDMA-assisted psychotherapy for PTSD; latest research on psychedelics; and more.Related episodes:Anesthesia, Placebo Effects, Consciousness, Subjectivity, MDMA, Ketamine, Opioids, Psychedelics | Boris Heifets | #163DMT, Serotonin, Inflammation, Psychedelics, and Past, Present & Future of Psychedelic Medicine | David & Charles Nichols | #137*This content is never meant to serve as medical advice.Support the Show.All episodes (audio & video), show notes, transcripts, and more at the M&M Substack Try Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.Try SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount.Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.Learn all the ways you can support my efforts
About the guest: Boris Heifets, MD, PhD is an anesthesiologist and researcher at Stanford University. His lab studies non-ordinary states of consciousness and psychoactive drugs like MDMA, ketamine, and psychedelics.Episode summary: Nick and Dr. Heifets discuss: anesthesia and how anesthetics work; placebo effects & expectations in clinical research; ketamine as an antidepressant, anesthetic, and recreational drug; the subjective effects of psychedelics and other drugs; MDMA and Lykos Therapeutics' attempts to gain FDA approval for MDMA-assisted psychotherapy; opioids & placebo effects; and more.Related episodes:How Does Ketamine Work & Is It Addictive? | Christian Lüscher | #90Consciousness, Anesthesia, Coma, Vegetative States, Sleep Pills (Ambien), Ketamine, AI & ChatGPT | Alex Proekt | #101*This content is never meant to serve as medical advice.Support the Show.All episodes (audio & video), show notes, transcripts, and more at the M&M Substack Try Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.Try SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount.Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for $50 off.Learn all the ways you can support my efforts
#302 In this episode, Guy welcomed back Niraj Naik. Niraj discussed the importance of taking action when manifesting results through the Law of Attraction. He emphasized that success comes from those who take the right actions, not just those who visualize without taking any steps. Niraj reflected on the growth of Soma Breath over the past four and a half years, from the early days of instructor training to now having over two and a half thousand instructors. He highlighted the need to integrate work and lifestyle, emphasizing the importance of enjoying and loving what you do to avoid it feeling like work. About Niraj: Niraj Naik is a professional musician and pharmacist turned holistic health and breathwork expert. He started his path in healing others, as a community pharmacist, yet after several years he found himself a patient with stress-related depression and ulcerative colitis. This was a wake-up call that made him embark on a journey of profound self-healing and education. He created a global community of heart-centred changemakers by founding SOMA Breath - the global breathwork and wellness movement with over 2000 certified instructors, and hundreds of thousands of students around the globe. Known internationally as the Renegade Pharmacist, Niraj is dedicated to educating others on topics of holistic health, breathwork, meditation, and more. Niraj's breathwork is advocated by some top names in wellness such as Ben Greenfield, Marisa Peer, Vishen Lakhiani, and Josh Trent of Wellness Force Radio and his techniques are currently being studied by leading neuroscientists at Cambridge University. In addition to the global breathwork and wellness movement, Niraj has created many other brands related to health and healing and was featured in articles from multiple news outlets across the world as well as hundreds of podcasts. Key Points Discussed: (00:00) - The SECRET Ingredient to Manifesting That No One Talks About. (04:47) - The importance of breath work. (09:33) - The Power of Placebo Effects. (14:21) - Practicing for Success. (19:30) - Power of rhythmic breathing. (24:39) - Amplifying feelings with color. (25:23) - Healing childhood traumas through reframing. (31:46) - Crazy transformative healing results. (33:21) - Transformative Mindvalley quest journey. (39:18) - Slow exercises with reduced breathing. (43:14) - Fitness and Psoas Muscle Discovery. (47:34) - Epic transformational live events. (50:08) - Building broadcast list tips. How to Contact Niraj Naik:www.somabreath.com About me:My Instagram: www.instagram.com/guyhlawrence/?hl=en Guy's websites:www.guylawrence.com.au www.liveinflow.co''
In this episode, I discuss placebo and belief and mindset effects — all of which exert a powerful and real influence on our biology and psychology. I discuss how your beliefs and expectation that a certain outcome will occur after taking a substance (or any intervention cause genuine changes in brain and bodily function. I discuss how placebos can change neurotransmitter and hormone release, pain levels, whether the stress response is beneficial or detrimental and more. I also explain how placebo effects can work with traditional drug or behavioral treatments to help improve health outcomes and why some people are more susceptible to placebo effects. By the end of the episode, listeners will understand the placebo effect, how it works, and how beliefs and mindsets can be leveraged toward mental health, physical health, and performance goals. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://www.eightsleep.com/huberman AeroPress: https://aeropress.com/huberman Levels: https://levels.link/huberman InsideTracker: https://insidetracker.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) Placebo Effects (00:02:40) Sponsors: Eight Sleep, AeroPress & Levels (00:07:24) Placebo, Nocebo vs. Belief Effect, Prefrontal Cortex (00:14:03) Dopamine, Placebo & Parkinson's Disease; Placebo Controls (00:21:36) Hormone Release & Placebo Effect, Paired Associations (00:28:52) Conditioning Effect & Insulin; Pavlovian Response (00:32:50) Sponsor: AG1 (00:34:17) Context & Expectations; Placebo Effect & Brain (00:40:51) Cancer, Mind-Body Practices; Placebo Effects & Limits (00:44:54) Asthma, Specificity & Placebo Effects (00:48:01) Sponsor: InsideTracker (00:49:03) Nicotine & Dose-Dependent Placebo Effects (00:55:31) Placebo Effects vs. Belief Effects, Food & Mindset (01:01:02) Exercise & Belief Effects (01:04:08) Placebo Effect, Brain & Stress Response (01:11:18) Individual Variation, Genetics & Placebo Effect (01:16:11) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer
On this episode of Sports Science Dudes, Dr. Chen shares how Radicle Science is using AI to transform clinical trials. This method not only garners authentic data but also reflects a true picture of how wellness products perform in the chaos of daily life.Timeline:2:00 The process of how Radicle Science works4:45 How do research subjects respond if an investigator is not present?10:19 Adherence in these studies11:39 The placebo effect12:33 If you tell someone they are getting a placebo, they'll still improve if you tell them it will help them15:44 What's the latest on CBD? Need a 100 mg dose or higher20:30 Crowdsourcing as part of running a study23:46 Who is the PI using the Radicle Science model? The data is owned by the client26:40 What are the main endpoints that can be done by Radicle Science? Cost is 100k for a trial with a sample of 50030:12 Radicle Science may serve as a good model for very active adults or elite athletes (e.g., sleep quality)33:35 Longevity – Dr Chen's philosophy40:16 Evolutionary reasons – humans didn't have many glucose spikes41:26 Dr Chen's way of making rice! Dr. Jeff Chen, MD, MBA is an impact entrepreneur, executive, physician, and scientist on a mission to transform the health of our bodies and minds using non-pharmaceutical products. He is co-founder/CEO of Radicle Science, an AI-driven healthtech B-Corp providing history's first Proof-as-a-Service solution for wellness products to easily prove their true effects at unprecedented affordability, speed, and scale. Radicle Science was named by KPMG as one of the Top Ten US “Tech Innovators” of 2022 and by Fast Company as a “World Changing Idea”. Dr. Jeff gave a MainStage Talk on Radicle Science at TED 2023. Previously he was the founder and Executive Director of a UCLA research center where he led clinical trials on natural products. Dr. Jeff has been interviewed by outlets including CNN, Forbes, Wall Street Journal, TIME, NPR, Entrepreneur, Rolling Stone, NBC News, Financial Times, WebMD, Politico, Business Insider, SF Gate, VICE, Vogue and more for his expertise. Following a BS at Cornell, Dr. Jeff earned his MD and MBA concurrently at UCLA.About the ShowWe cover all things related to sports science, nutrition, and performance. The Sports Science Dudes represent the opinions of the hosts and guests and are not the official opinions of the International Society of Sports Nutrition (ISSN), the Society for Sports Neuroscience, or Nova Southeastern University. The advice provided on this show should not be construed as medical advice and is purely an educational forum.Hosted by Jose Antonio, PhDDr. Antonio is the co-founder and CEO of the International Society of Sports Nutrition and the co-founder of the Society for Sports Neuroscience, www.issn.net. Dr. Antonio has over 120 peer-reviewed publications and 16 books. He is a Professor at Nova Southeastern University, Davie, Florida in the Department of Health and Human Performance.Twitter: @JoseAntonioPhDInstagram: the_issn and supphdCo-host Anthony Ricci EdDDr Ricci is an expert on Fight Sports and is currently an Assistant Professor at Nova Southeastern University in Davie Florida in the Department of Health and Human Performance.Instagram: sportpsy_sci_doc and fightshape_ricci
Millions experience unwanted side effects from mental health medications. But what if a placebo could offer similar benefits, without the risks? Join us as we explore the role of the placebo effect and what it means when referenced in clinical studies compared to SSRI's. With genuine informed consent many clients might choose a different path. We'll unveil practical strategies to harness the placebo response for improved mental well-being, beyond the realm of traditional therapy. Implementing these techniques in therapy and outpatient settings could lead to profound positive changes and even save lives.Substack: The Power of the Placebo Response in Mental Health@DrMcFillin X Post: Dec 27, 2023 Informed Consent Note: This podcast episode is designed solely for informational and educational purposes, without endorsing or promoting any specific medical treatments. We strongly advise consulting with a qualified healthcare professional before making any medical decisions or taking any actions.*If you are in crisis or believe you have an emergency, please contact your doctor or dial 911. If you are contemplating suicide, call 1-800-273-TALK to speak with a trained and skilled counselor.RADICALLY GENUINE PODCASTDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / X (Twitter)Substack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically Genuine—-----------FREE DOWNLOAD! DISTRESS TOLERANCE SKILLS—----------ADDITIONAL RESOURCES9:00 - A Model of Placebo Response in Antidepressant Clinical Trials - PMC14:00 - Antidepressants Nearly Ruined my Marriage23:00 - Placebo Effects in Oncology | JNCI: Journal of the National Cancer Institute | Oxford Academic24:00 - A fascinating landmark study of placebo surgery for knee osteoarthritis32:00 - The nocebo effect and its relevance for clinical practice - PMC37:00 - Change your mindset, change the game | Dr. Alia Crum | TEDxTraverseCity41:00 - Cognitive-Behavior Therapy, Sertraline, and Their Combination for Children and Adolescents With Obsessive-Compulsive Disorder: The Pediatric OCD Treatment Study (POTS) Randomized Controlled Trial
Nella rubrica Contemporaneamente, Mariantonietta Firmani intervista il neuroscienziato Fabrizio Benedetti esperto mondiale di effetto placebo, e la filosofa Franca D'Agostini esperta di logica. L'intervista è in Contemporaneamente di Mariantonietta Firmani, il podcast divulgato da Artribune.com e Parallelo42.it In Contemporaneamente podcast trovate incontri tematici con autorevoli interpreti del contemporaneo tra arte e scienza, letteratura, storia, filosofia, architettura, cinema e molto altro. Per approfondire questioni auliche ma anche cogenti e futuribili. Dialoghi straniati per accedere a nuove letture e possibili consapevolezze dei meccanismi correnti: tra locale e globale, tra individuo e società, tra pensiero maschile e pensiero femminile, per costruire una visione ampia, profonda ed oggettiva della realtà. Fabrizio Benedetti e Franca D'Agostini ci raccontano di neuroscienze e filosofia, malattia del corpo e deviazioni del pensiero collettivo. Ci parlano di effetto placebo, del potere della fiducia tra fattori psicosociali e rituale della cura; e della verità come funzione concettuale. Nell'era dell'iper-tecnologia il giocatore d'azzardo soffre di deficit di dopamina, e l'essere umano ha perso la capacità di escludere, e molto altro. GUARDA IL VIDEO!! https://youtu.be/NKpWqpvN6DE BREVI NOTE BIOGRAFICHE DEGLI AUTORI Fabrizio Benedetti neuroscienziato, Ordinario di Neurofisiologia all'Università di Torino, Senior Advisor alla Harvard University, Cambridge, USA; dirige la Hypoxia Medicine di Plateau Rosà Zermatt, Svizzera. Membro di molti autorevoli enti internazionali tra cui: Academy of Europe; European Working Group on Pain and Impaired Cognition; European Dana Alliance for the Brain.Autore di numerosi articoli su riviste scientifiche, dal 2009 è nella redazione di: “Pain” e “Current Neuropharmacology”; relatore in autorevoli convegni in tutto il mondo. Inoltre è autore di diverse pubblicazioni, tra le ultime edite da Oxford University Press, tradotti in italiano: “Placebo Effects”, 3rd Edition 2020; “The Patient's Brain”2010. È anche autore di libri divulgativi: “La Speranza è un Farmaco” 2018 e “Il Cacciatore di Ricordi” 2021. Infine, tra i numerosi premi riceve: 1985 Silbert International Award at the University of California Los Angeles; 1997 Novartis Prize of the Italian Society for Neuroscience. Ed anche: 2010 Medical Book Award della British Medical Association; 2015 William S Kroger Award of the American Society of Clinical Hypnosis, e molto altro. Franca D'Agostini filosofa, laurea e PhD in filosofia all'Università di Torino, insegna Logic and Critical Thinking all'Università Statale di Milano. Si occupa di logica filosofica, metafisica, filosofia del Novecento, uso pubblico della filosofia.Autrice di 15 pubblicazioni tematiche, e un centinaio di articoli su riviste scientifiche internazionali; collabora con: La Stampa, Lettura del Corriere della Sera, il Manifesto. Tra i molti temi affrontati, ha lavorato sui rapporti tra filosofia anglo-americana e filosofia europea in “Analitici e continentali” 1997. Inoltre è autrice di: “Paradossi” 2009; “Disavventure della verità” 2002; “Verità avvelenata” 2010; “Introduzione alla verità” 2011, “Logica del nichilismo” 2000, ed altri. Poi, con Maurizio Ferrera, ha pubblicato “La verità al potere. Sei diritti aletici” 2019. Tra gli altri i suoi libri in italiano: “Breve storia della filosofia nel Novecento” 1999; “Menzogna” 2012; “Realismo? Una questione non controversa” 2013; e altro.
Dr. Jeremy Howick has spent his career studying evidence-based medicine as well as placebo effects. In part, this started from when he was a competitive rower, developed an allergy to a cat, and was prescribed ginger tea as a treatment. Dr. Jeremy Howick, PhD is the Director of the Stoneygate Centre for Excellence in Empathic Healthcare and a Senior Researcher at Oxford University. He is the author of Doctor You and The Philosophy of Evidence-Based Medicine as well as a book released November 14, 2023, The Power of Placebos: How the Science of Placebos and Nocebos Can Improve Health Care. He obtained his PhD from the London School of Economics.
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Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.14.527858v1?rss=1 Authors: Khalid, I., Rodrigues, B., Dreyfus, H., Frileux, S., Meissner, K., Fossati, P., Hare, T. A., Schmidt, L. Abstract: Expectancies, which are higher order prognostic beliefs, can have powerful effects on experiences, behavior and brain. However, it is unknown where, how, and when, in the brain, prognostic beliefs influence appetitive interoceptive experiences and related economic behavior. This study combined a placebo intervention on hunger with computational modelling and functional magnetic resonance imaging of value-based decision-making. The results show that prognostic beliefs about hunger shape hunger experiences, how much participants value food and food-value encoding in the prefrontal cortex. Computational modelling further revealed that these placebo effects were underpinned by how much and when during the decision process taste and health information are integrated into the accumulation of evidence toward a food choice. The drift weights of both sources of information further moderated ventromedial and dorsolateral prefrontal cortex interactions during choice formation. These findings provide novel insights into the neurocognitive mechanisms that translate higher order prognostic beliefs into non-aversive interoceptive sensitivity and shape decision-making. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Huberman Lab Podcast Notes Key Takeaways “Behavioral tools form the foundational layer of all tools for mental health, physical health, and performance. Second to that, the next layer is nutrition. No amount of supplementation or non-prescription or prescription compounds can ever compensate for poor nutrition.” – Dr. Andrew HubermanNutrition is fundamentally important for obtaining basic nutrients, micro-, and macronutrients – supplements should be used to augment or support behavioral tools and nutritionGeneral approach to vitamin & mineral supplements: (1) is the cost within the range you can afford and want to pay; (2) are you able to cover needs just from food (you want most food to come from minimally or non-processed foods)Three questions to ask yourself before starting supplementation: (1) how's your sleep? (2) how's your nutrition? (3) what's your budget?Unless you are supplementing for foundational support (vitamins, minerals, foundational compounds, adaptogens, probiotics, prebiotics), focus on single-ingredient formulated supplements for the most power and control overdoseDon't try everything at once when trying to address a specific problem! Instead, try one supplement for one week (without varying anything else) than the other to see which works best for you – then see how well the combination worksImportant note for women seeking fertility and hormone support: depending on the phase of your menstrual cycle, supplements will impact you differently since hormones are naturally fluctuating – it's critical (for everyone, not just women) to take single-ingredient supplements so you can dose accordinglyIf the budget is around $100 per month: don't focus on trying to improve one specific area or category; instead, focus on buffering and enhancing foundational nutrition, adaptogens, probiotics, prebiotics, and digestive enzymes – check out Athletic greensRead the full notes @ podcastnotes.orgIn this episode, I explain how to design a supplementation protocol to support maximum mental and physical health and performance depending on your specific needs, nutrition, lifestyle and finances. When most people hear about “supplements,” they think they are vitamin supplements, but there are many compounds that are powerful and sold over-the-counter that can enhance our health in performance and that can't be obtained from foods. First, I discuss “foundational” supplements to support overall health, including water and fat-soluble vitamins, minerals, digestive enzymes, adaptogens, and prebiotics/probiotics. Then I explain how to use single-ingredient supplements to enhance specific aspects of your physiology, such as aiding sleep, cognitive enhancement, and focus supporting healthy hormone levels (e.g., testosterone, estrogen and growth hormone, thyroid). Finally, I explain when it makes sense to add supplements to your lifestyle and discuss how best to use supplements, including how to determine dosage, sourcing, continuous schedules and cycling, and how to layer different supplements most effectively. This episode will explain how to design the safest, most biologically effective, cost-effective supplementation protocol to meet your particular goals and support your overall health, including vitality and longevity. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Supplements (00:03:38) Hierarchy of Tools/Interventions, Developing a Supplementation Protocol (00:11:51) Momentous, LMNT, Helix Sleep (00:15:38) Role of Supplements, Foundational Supplements, Water/Fat-Soluble Vitamins (00:21:07) Supplement Considerations: Cost, Nutrition & Schedule (00:25:25) Foundational Supplements, Digestive Enzymes, Adaptogens (00:28:04) Gut Microbiome, Probiotics/Prebiotics & Nutrition (00:33:06) Supplements for Gut Microbiome, Brain Fog (00:35:59) InsideTracker (00:36:44) Adaptogens & Broad-Spectrum Foundational Supplements (00:38:35) Core Supplement Questions & Meeting Foundational Needs (00:43:45) Supplements to Support Sleep: Myo-Inositol, Theanine (00:50:52) Supplements for Falling Asleep: Magnesium Threonate/Bisglycinate, Apigenin (00:55:55) Melatonin Caution (00:58:11) Supplement Dependency?, Placebo Effects (01:02:45) AG1 (Athletic Greens) (01:03:53) Nutrition & Behavior for Hormone Health (01:08:59) Hormone Health: Shilajit, Ashwagandha, L-Carnitine, Maca Root (01:12:48) Growth Hormone: Behaviors, Arginine, Prescriptions (01:16:04) Testosterone/Estrogen: Fadogia Agrestis; Bloodwork (01:23:06) Testosterone Supplement: Tongkat Ali, Libido (01:27:24) Menstrual Cycle, Birth Control & Fertility (01:30:54) Cognitive Enhancement & Focus, Sleep, Stimulants: Caffeine (01:36:57) Adrenaline & Stimulants: Yohimbine, Rauwolscine (01:38:55) Adjusting Neurotransmitters: Alpha-GPC, L-Tyrosine; Layering Supplements (01:43:58) Cognitive, Mood & Metabolic Support: Omega-3 Fatty Acids (01:47:25) Food-Mimic Supplements, Protein (01:50:09) Kids, Aging & Supplements (01:55:25) A Rational Supplementation Protocol (01:58:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Title Card Photo Credit: Mike Blabac
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I explain how to design a supplementation protocol to support maximum mental and physical health and performance depending on your specific needs, nutrition, lifestyle and finances. When most people hear about “supplements,” they think they are vitamin supplements, but there are many compounds that are powerful and sold over-the-counter that can enhance our health in performance and that can't be obtained from foods. First, I discuss “foundational” supplements to support overall health, including water and fat-soluble vitamins, minerals, digestive enzymes, adaptogens, and prebiotics/probiotics. Then I explain how to use single-ingredient supplements to enhance specific aspects of your physiology, such as aiding sleep, cognitive enhancement, and focus supporting healthy hormone levels (e.g., testosterone, estrogen and growth hormone, thyroid). Finally, I explain when it makes sense to add supplements to your lifestyle and discuss how best to use supplements, including how to determine dosage, sourcing, continuous schedules and cycling, and how to layer different supplements most effectively. This episode will explain how to design the safest, most biologically effective, cost-effective supplementation protocol to meet your particular goals and support your overall health, including vitality and longevity. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Supplements (00:03:38) Hierarchy of Tools/Interventions, Developing a Supplementation Protocol (00:11:51) Momentous, LMNT, Helix Sleep (00:15:38) Role of Supplements, Foundational Supplements, Water/Fat-Soluble Vitamins (00:21:07) Supplement Considerations: Cost, Nutrition & Schedule (00:25:25) Foundational Supplements, Digestive Enzymes, Adaptogens (00:28:04) Gut Microbiome, Probiotics/Prebiotics & Nutrition (00:33:06) Supplements for Gut Microbiome, Brain Fog (00:35:59) InsideTracker (00:36:44) Adaptogens & Broad-Spectrum Foundational Supplements (00:38:35) Core Supplement Questions & Meeting Foundational Needs (00:43:45) Supplements to Support Sleep: Myo-Inositol, Theanine (00:50:52) Supplements for Falling Asleep: Magnesium Threonate/Bisglycinate, Apigenin (00:55:55) Melatonin Caution (00:58:11) Supplement Dependency?, Placebo Effects (01:02:45) AG1 (Athletic Greens) (01:03:53) Nutrition & Behavior for Hormone Health (01:08:59) Hormone Health: Shilajit, Ashwagandha, L-Carnitine, Maca Root (01:12:48) Growth Hormone: Behaviors, Arginine, Prescriptions (01:16:04) Testosterone/Estrogen: Fadogia Agrestis; Bloodwork (01:23:06) Testosterone Supplement: Tongkat Ali, Libido (01:27:24) Menstrual Cycle, Birth Control & Fertility (01:30:54) Cognitive Enhancement & Focus, Sleep, Stimulants: Caffeine (01:36:57) Adrenaline & Stimulants: Yohimbine, Rauwolscine (01:38:55) Adjusting Neurotransmitters: Alpha-GPC, L-Tyrosine; Layering Supplements (01:43:58) Cognitive, Mood & Metabolic Support: Omega-3 Fatty Acids (01:47:25) Food-Mimic Supplements, Protein (01:50:09) Kids, Aging & Supplements (01:55:25) A Rational Supplementation Protocol (01:58:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Title Card Photo Credit: Mike Blabac
In this episode, I explain how to design a supplementation protocol to support maximum mental and physical health and performance depending on your specific needs, nutrition, lifestyle and finances. When most people hear about “supplements,” they think they are vitamin supplements, but there are many compounds that are powerful and sold over-the-counter that can enhance our health in performance and that can't be obtained from foods. First, I discuss “foundational” supplements to support overall health, including water and fat-soluble vitamins, minerals, digestive enzymes, adaptogens, and prebiotics/probiotics. Then I explain how to use single-ingredient supplements to enhance specific aspects of your physiology, such as aiding sleep, cognitive enhancement, and focus supporting healthy hormone levels (e.g., testosterone, estrogen and growth hormone, thyroid). Finally, I explain when it makes sense to add supplements to your lifestyle and discuss how best to use supplements, including how to determine dosage, sourcing, continuous schedules and cycling, and how to layer different supplements most effectively. This episode will explain how to design the safest, most biologically effective, cost-effective supplementation protocol to meet your particular goals and support your overall health, including vitality and longevity. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Supplements (00:03:38) Hierarchy of Tools/Interventions, Developing a Supplementation Protocol (00:11:51) Momentous, LMNT, Helix Sleep (00:15:38) Role of Supplements, Foundational Supplements, Water/Fat-Soluble Vitamins (00:21:07) Supplement Considerations: Cost, Nutrition & Schedule (00:25:25) Foundational Supplements, Digestive Enzymes, Adaptogens (00:28:04) Gut Microbiome, Probiotics/Prebiotics & Nutrition (00:33:06) Supplements for Gut Microbiome, Brain Fog (00:35:59) InsideTracker (00:36:44) Adaptogens & Broad-Spectrum Foundational Supplements (00:38:35) Core Supplement Questions & Meeting Foundational Needs (00:43:45) Supplements to Support Sleep: Myo-Inositol, Theanine (00:50:52) Supplements for Falling Asleep: Magnesium Threonate/Bisglycinate, Apigenin (00:55:55) Melatonin Caution (00:58:11) Supplement Dependency?, Placebo Effects (01:02:45) AG1 (Athletic Greens) (01:03:53) Nutrition & Behavior for Hormone Health (01:08:59) Hormone Health: Shilajit, Ashwagandha, L-Carnitine, Maca Root (01:12:48) Growth Hormone: Behaviors, Arginine, Prescriptions (01:16:04) Testosterone/Estrogen: Fadogia Agrestis; Bloodwork (01:23:06) Testosterone Supplement: Tongkat Ali, Libido (01:27:24) Menstrual Cycle, Birth Control & Fertility (01:30:54) Cognitive Enhancement & Focus, Sleep, Stimulants: Caffeine (01:36:57) Adrenaline & Stimulants: Yohimbine, Rauwolscine (01:38:55) Adjusting Neurotransmitters: Alpha-GPC, L-Tyrosine; Layering Supplements (01:43:58) Cognitive, Mood & Metabolic Support: Omega-3 Fatty Acids (01:47:25) Food-Mimic Supplements, Protein (01:50:09) Kids, Aging & Supplements (01:55:25) A Rational Supplementation Protocol (01:58:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Title Card Photo Credit: Mike Blabac
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.01.518177v1?rss=1 Authors: Schelski, D. S., Scheele, D., Schmidt, L., Hurlemann, R., Weber, B., Plassmann, H. Abstract: Expectations about the quality of a medical treatment influence how much an inert treatment helps to improve patient well-being. Similarly, expectations about the quality of products influence how identical goods and services are evaluated differently after their consumption. One driver for such "placebo effects" in medical treatments is social cognition in the form of trust, which may be influenced by the hormone oxytocin. An open question is whether trust and oxytocin play similar roles in marketing placebo effects. To answer this question, we combined oxytocin administration (24 IU) and trust questionnaires in a pre-registered double-blind randomized between-subjects study design (N food tasting task = 223; N cognitive performance task = 202). We could not find evidence that oxytocin and trust play a role in placebo effects of marketing actions. Together with other recent null findings from oxytocin administration studies, these findings question the role trust might play in different types of placebo effects. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Huberman Lab Podcast Notes Key Takeaways Food has to be broken down and systematically put into forms the body can use for energyExercise is the hack – “Exercise is the only thing you can do to actually improve your biomarkers of health without even losing weight.” – Dr. Layne NortonCreating a new identity: people don't just eat because they're hungry – there are major social and psychological elements to eating that need to be addressed when becoming healthier; in extremes, you may need a new communityThe best diet is the one you can stick to forever – pick the form of restriction that feels least restrictive to you – this could be time-restricted or calorie restrictedWhat we know about gut health: (1) more diversity is better; (2) soluble fiber is positive and acts as a prebiotic; (3) prebiotics work better than probiotics; (4) some evidence that saturated fat is not good for microbiota (this theory is in its infancy); (5) exerciseProtein is the biggest lever you can pull for lean body mass – try making small changes to increase protein to existing meals and reach your daily goal (~1.6g-2.6g/kg body weight)Don't fall into the trap of looking at an acute response to something and assuming that is what the long-term outcome will be – anything is bad for you in the wrong doseIt's possible to hit protein targets using plant protein sources but most are packaged in carbohydrates and/or fat so may be difficult to maintain calories and macrosIt's no mystery – the obesity epidemic is a result of increased caloric intake and reduced physical activityFocus less on sugar and more on fiber: sugar doesn't have any positive health benefits but if you're controlling calories and maintaining fiber intake you will likely achieve balance – don't go wild on sugar but don't focus on restriction because you'll likely end up bingingThe more adipose tissue you have, the more aggressively you can diet without consequences to lean mass or health because the body doesn't need to metabolize lean tissue“If you do what's easy in the short term, your life will be hard; if you do what's hard in the short term, your life will get easier.” – Dr. Layne NortonBottom line on seed oils: you're better off monitoring oil intake from a caloric standpoint but there doesn't seem to be enough evidence to demonize seed oilTip: keep saturated fats within 7-10% of daily caloric intakeThere's no hack for doing hard things! You can't out-supplement hard training and eating well – enjoy the processRead the full notes @ podcastnotes.orgMy guest is Layne Norton, Ph.D. — one of the world's foremost experts in nutrition, protein metabolism, muscle gain and fat loss. We discuss the science of energy utilization and balance, the efficacy of different diets (e.g., ketogenic, vegan, vegetarian, carnivore, omnivore), and how best to build lean muscle mass and lose fat. We also discuss optimal protein and fiber intake, the best sources of protein, the correlation between appetite, satiety signals and exercise, along with male and female-specific needs. Dr. Norton also explains how to support a healthy gut microbiome and offers insight into sugar and artificial sweeteners, processed, cooked, and raw foods, supplements, seed oils, and the relationship of LDL/HDL levels to cardiovascular health. This episode serves as a master class in nutrition, metabolism and exercise and is sure to benefit people of all ages and with different health and fitness goals. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://www.drinklmnt.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Layne Norton, Nutrition & Fitness (00:02:53) LMNT, ROKA, InsideTracker, Momentous (00:06:50) Calories & Cellular Energy Production (00:12:35) Energy Balance, Food Labels, Fiber (00:15:19) Resting Metabolic Rate, Thermic Effect of Food (00:19:04) Exercise & Non-Exercise Activity Thermogenesis (NEAT) (00:25:49) Losing Weight, Tracking Calories, Daily Weighing (00:29:24) Post-Exercise Metabolic Rate, Appetite (00:35:04) AG1 (Athletic Greens) (00:36:19) Exercise & Appetite, Calorie Trackers, Placebo Effects & Beliefs (00:43:46) Exercise & Satiety Signals, Maintain Weight Loss & Identity (00:56:32) Weight Loss & Maintenance, Diet Adherence (01:03:33) Restrictive Diets & Transition Periods (01:08:03) Gut Health & Appetite (01:16:23) Tool: Supporting Gut Health, Fiber & Longevity (01:23:59) LDL, HDL & Cardiovascular Disease (01:30:31) Leucine, mTOR & Protein Synthesis (01:37:31) Tool: Daily Protein Intake & Muscle Mass (01:44:24) Protein & Fasting, Lean Body Mass (01:55:38) Plant-Based Proteins: Whey, Soy, Leucine, Corn, Pea (02:04:28) Processed Foods (02:11:54) Obesity Epidemic, Calorie Intake & Energy Output (02:17:33) Obesity, Sugar & Fiber, Restriction & Craving (02:25:57) Artificial Sweeteners & Blood Sugar (02:38:55) Artificial Sweeteners & Gut Microbiome, Sucralose, Blood Sugar (02:50:19) Rapid Weight Loss, Satiety & Beliefs (02:58:13) Seed Oils & Obesity, Saturated Fat, Overall Energy Toxicity (03:08:15) Females, Diet, Exercise & Menstrual Cycles (03:14:05) Raw vs. Cooked Foods (03:16:32) Berberine & Glucose Scavenging (03:19:12) Fiber & Gastric Emptying Time (03:21:00) Supplements, Creatine Monohydrate, Rhodiola Rosea (03:30:33) Hard Training; Challenge & Mental Resilience (03:36:12) Carbon App (03:47:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Disclaimer: https://hubermanlab.com/disclaimer Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Huberman Lab Podcast Notes Key Takeaways Food has to be broken down and systematically put into forms the body can use for energyExercise is the hack – “Exercise is the only thing you can do to actually improve your biomarkers of health without even losing weight.” – Dr. Layne NortonCreating a new identity: people don't just eat because they're hungry – there are major social and psychological elements to eating that need to be addressed when becoming healthier; in extremes, you may need a new communityThe best diet is the one you can stick to forever – pick the form of restriction that feels least restrictive to you – this could be time-restricted or calorie restrictedWhat we know about gut health: (1) more diversity is better; (2) soluble fiber is positive and acts as a prebiotic; (3) prebiotics work better than probiotics; (4) some evidence that saturated fat is not good for microbiota (this theory is in its infancy); (5) exerciseProtein is the biggest lever you can pull for lean body mass – try making small changes to increase protein to existing meals and reach your daily goal (~1.6g-2.6g/kg body weight)Don't fall into the trap of looking at an acute response to something and assuming that is what the long-term outcome will be – anything is bad for you in the wrong doseIt's possible to hit protein targets using plant protein sources but most are packaged in carbohydrates and/or fat so may be difficult to maintain calories and macrosIt's no mystery – the obesity epidemic is a result of increased caloric intake and reduced physical activityFocus less on sugar and more on fiber: sugar doesn't have any positive health benefits but if you're controlling calories and maintaining fiber intake you will likely achieve balance – don't go wild on sugar but don't focus on restriction because you'll likely end up bingingThe more adipose tissue you have, the more aggressively you can diet without consequences to lean mass or health because the body doesn't need to metabolize lean tissue“If you do what's easy in the short term, your life will be hard; if you do what's hard in the short term, your life will get easier.” – Dr. Layne NortonBottom line on seed oils: you're better off monitoring oil intake from a caloric standpoint but there doesn't seem to be enough evidence to demonize seed oilTip: keep saturated fats within 7-10% of daily caloric intakeThere's no hack for doing hard things! You can't out-supplement hard training and eating well – enjoy the processRead the full notes @ podcastnotes.orgMy guest is Layne Norton, Ph.D. — one of the world's foremost experts in nutrition, protein metabolism, muscle gain and fat loss. We discuss the science of energy utilization and balance, the efficacy of different diets (e.g., ketogenic, vegan, vegetarian, carnivore, omnivore), and how best to build lean muscle mass and lose fat. We also discuss optimal protein and fiber intake, the best sources of protein, the correlation between appetite, satiety signals and exercise, along with male and female-specific needs. Dr. Norton also explains how to support a healthy gut microbiome and offers insight into sugar and artificial sweeteners, processed, cooked, and raw foods, supplements, seed oils, and the relationship of LDL/HDL levels to cardiovascular health. This episode serves as a master class in nutrition, metabolism and exercise and is sure to benefit people of all ages and with different health and fitness goals. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://www.drinklmnt.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Layne Norton, Nutrition & Fitness (00:02:53) LMNT, ROKA, InsideTracker, Momentous (00:06:50) Calories & Cellular Energy Production (00:12:35) Energy Balance, Food Labels, Fiber (00:15:19) Resting Metabolic Rate, Thermic Effect of Food (00:19:04) Exercise & Non-Exercise Activity Thermogenesis (NEAT) (00:25:49) Losing Weight, Tracking Calories, Daily Weighing (00:29:24) Post-Exercise Metabolic Rate, Appetite (00:35:04) AG1 (Athletic Greens) (00:36:19) Exercise & Appetite, Calorie Trackers, Placebo Effects & Beliefs (00:43:46) Exercise & Satiety Signals, Maintain Weight Loss & Identity (00:56:32) Weight Loss & Maintenance, Diet Adherence (01:03:33) Restrictive Diets & Transition Periods (01:08:03) Gut Health & Appetite (01:16:23) Tool: Supporting Gut Health, Fiber & Longevity (01:23:59) LDL, HDL & Cardiovascular Disease (01:30:31) Leucine, mTOR & Protein Synthesis (01:37:31) Tool: Daily Protein Intake & Muscle Mass (01:44:24) Protein & Fasting, Lean Body Mass (01:55:38) Plant-Based Proteins: Whey, Soy, Leucine, Corn, Pea (02:04:28) Processed Foods (02:11:54) Obesity Epidemic, Calorie Intake & Energy Output (02:17:33) Obesity, Sugar & Fiber, Restriction & Craving (02:25:57) Artificial Sweeteners & Blood Sugar (02:38:55) Artificial Sweeteners & Gut Microbiome, Sucralose, Blood Sugar (02:50:19) Rapid Weight Loss, Satiety & Beliefs (02:58:13) Seed Oils & Obesity, Saturated Fat, Overall Energy Toxicity (03:08:15) Females, Diet, Exercise & Menstrual Cycles (03:14:05) Raw vs. Cooked Foods (03:16:32) Berberine & Glucose Scavenging (03:19:12) Fiber & Gastric Emptying Time (03:21:00) Supplements, Creatine Monohydrate, Rhodiola Rosea (03:30:33) Hard Training; Challenge & Mental Resilience (03:36:12) Carbon App (03:47:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Disclaimer: https://hubermanlab.com/disclaimer Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Huberman Lab Podcast Notes Food has to be broken down and systematically put into forms the body can use for energyExercise is the hack – “Exercise is the only thing you can do to actually improve your biomarkers of health without even losing weight.” – Dr. Layne NortonCreating a new identity: people don't just eat because they're hungry – there are major social and psychological elements to eating that need to be addressed when becoming healthier; in extremes, you may need a new communityThe best diet is the one you can stick to forever – pick the form of restriction that feels least restrictive to you – this could be time-restricted or calorie restrictedWhat we know about gut health: (1) more diversity is better; (2) soluble fiber is positive and acts as a prebiotic; (3) prebiotics work better than probiotics; (4) some evidence that saturated fat is not good for microbiota (this theory is in its infancy); (5) exerciseProtein is the biggest lever you can pull for lean body mass – try making small changes to increase protein to existing meals and reach your daily goal (~1.6g-2.6g/kg body weight)Read the full notes @ podcastnotes.orgMy guest is Layne Norton, Ph.D. — one of the world's foremost experts in nutrition, protein metabolism, muscle gain and fat loss. We discuss the science of energy utilization and balance, the efficacy of different diets (e.g., ketogenic, vegan, vegetarian, carnivore, omnivore), and how best to build lean muscle mass and lose fat. We also discuss optimal protein and fiber intake, the best sources of protein, the correlation between appetite, satiety signals and exercise, along with male and female-specific needs. Dr. Norton also explains how to support a healthy gut microbiome and offers insight into sugar and artificial sweeteners, processed, cooked, and raw foods, supplements, seed oils, and the relationship of LDL/HDL levels to cardiovascular health. This episode serves as a master class in nutrition, metabolism and exercise and is sure to benefit people of all ages and with different health and fitness goals. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://www.drinklmnt.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Layne Norton, Nutrition & Fitness (00:02:53) LMNT, ROKA, InsideTracker, Momentous (00:06:50) Calories & Cellular Energy Production (00:12:35) Energy Balance, Food Labels, Fiber (00:15:19) Resting Metabolic Rate, Thermic Effect of Food (00:19:04) Exercise & Non-Exercise Activity Thermogenesis (NEAT) (00:25:49) Losing Weight, Tracking Calories, Daily Weighing (00:29:24) Post-Exercise Metabolic Rate, Appetite (00:35:04) AG1 (Athletic Greens) (00:36:19) Exercise & Appetite, Calorie Trackers, Placebo Effects & Beliefs (00:43:46) Exercise & Satiety Signals, Maintain Weight Loss & Identity (00:56:32) Weight Loss & Maintenance, Diet Adherence (01:03:33) Restrictive Diets & Transition Periods (01:08:03) Gut Health & Appetite (01:16:23) Tool: Supporting Gut Health, Fiber & Longevity (01:23:59) LDL, HDL & Cardiovascular Disease (01:30:31) Leucine, mTOR & Protein Synthesis (01:37:31) Tool: Daily Protein Intake & Muscle Mass (01:44:24) Protein & Fasting, Lean Body Mass (01:55:38) Plant-Based Proteins: Whey, Soy, Leucine, Corn, Pea (02:04:28) Processed Foods (02:11:54) Obesity Epidemic, Calorie Intake & Energy Output (02:17:33) Obesity, Sugar & Fiber, Restriction & Craving (02:25:57) Artificial Sweeteners & Blood Sugar (02:38:55) Artificial Sweeteners & Gut Microbiome, Sucralose, Blood Sugar (02:50:19) Rapid Weight Loss, Satiety & Beliefs (02:58:13) Seed Oils & Obesity, Saturated Fat, Overall Energy Toxicity (03:08:15) Females, Diet, Exercise & Menstrual Cycles (03:14:05) Raw vs. Cooked Foods (03:16:32) Berberine & Glucose Scavenging (03:19:12) Fiber & Gastric Emptying Time (03:21:00) Supplements, Creatine Monohydrate, Rhodiola Rosea (03:30:33) Hard Training; Challenge & Mental Resilience (03:36:12) Carbon App (03:47:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Disclaimer: https://hubermanlab.com/disclaimer Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
My guest is Layne Norton, Ph.D. — one of the world's foremost experts in nutrition, protein metabolism, muscle gain and fat loss. We discuss the science of energy utilization and balance, the efficacy of different diets (e.g., ketogenic, vegan, vegetarian, carnivore, omnivore), and how best to build lean muscle mass and lose fat. We also discuss optimal protein and fiber intake, the best sources of protein, the correlation between appetite, satiety signals and exercise, along with male and female-specific needs. Dr. Norton also explains how to support a healthy gut microbiome and offers insight into sugar and artificial sweeteners, processed, cooked, and raw foods, supplements, seed oils, and the relationship of LDL/HDL levels to cardiovascular health. This episode serves as a master class in nutrition, metabolism and exercise and is sure to benefit people of all ages and with different health and fitness goals. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://www.drinklmnt.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Layne Norton, Nutrition & Fitness (00:02:53) LMNT, ROKA, InsideTracker, Momentous (00:06:50) Calories & Cellular Energy Production (00:12:35) Energy Balance, Food Labels, Fiber (00:15:19) Resting Metabolic Rate, Thermic Effect of Food (00:19:04) Exercise & Non-Exercise Activity Thermogenesis (NEAT) (00:25:49) Losing Weight, Tracking Calories, Daily Weighing (00:29:24) Post-Exercise Metabolic Rate, Appetite (00:35:04) AG1 (Athletic Greens) (00:36:19) Exercise & Appetite, Calorie Trackers, Placebo Effects & Beliefs (00:43:46) Exercise & Satiety Signals, Maintain Weight Loss & Identity (00:56:32) Weight Loss & Maintenance, Diet Adherence (01:03:33) Restrictive Diets & Transition Periods (01:08:03) Gut Health & Appetite (01:16:23) Tool: Supporting Gut Health, Fiber & Longevity (01:23:59) LDL, HDL & Cardiovascular Disease (01:30:31) Leucine, mTOR & Protein Synthesis (01:37:31) Tool: Daily Protein Intake & Muscle Mass (01:44:24) Protein & Fasting, Lean Body Mass (01:55:38) Plant-Based Proteins: Whey, Soy, Leucine, Corn, Pea (02:04:28) Processed Foods (02:11:54) Obesity Epidemic, Calorie Intake & Energy Output (02:17:33) Obesity, Sugar & Fiber, Restriction & Craving (02:25:57) Artificial Sweeteners & Blood Sugar (02:38:55) Artificial Sweeteners & Gut Microbiome, Sucralose, Blood Sugar (02:50:19) Rapid Weight Loss, Satiety & Beliefs (02:58:13) Seed Oils & Obesity, Saturated Fat, Overall Energy Toxicity (03:08:15) Females, Diet, Exercise & Menstrual Cycles (03:14:05) Raw vs. Cooked Foods (03:16:32) Berberine & Glucose Scavenging (03:19:12) Fiber & Gastric Emptying Time (03:21:00) Supplements, Creatine Monohydrate, Rhodiola Rosea (03:30:33) Hard Training; Challenge & Mental Resilience (03:36:12) Carbon App (03:47:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Disclaimer: https://hubermanlab.com/disclaimer Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
With Twittering Machines' Michael Lavorgna. PATREON: https://www.patreon.com/johndarko Show notes: https://darko.audio/2021/10/podcast-27-working-hours-placebo-effects-cheap-streaming/ Producer: Nick McCorriston Music: Ben Pit -- https://soundcloud.com/beniospit/hybrid-rhythms
In this episode we discuss the placebo effect, and some famous examples of this phenomenon. In research, placebos are used to determine if what is being studied has a significant affect above and beyond what we believe will happen. As essentially, a placebo can be extremely effective if we believe if will have an affect. So in essence, our mind can determine how effective something is. This can be witnessed in multiple different areas, especially when it comes to supplementation, diets and training programmes.
Bạn sẽ nghĩ thế nào khi nghe được việc não bộ có thể giúp chúng ta giảm đi triệu chứng của các căn bệnh mà không cần sự hỗ trợ của bất kỳ loại thuốc nào ngoài một dòng suy nghĩ ? Đã có cả một mảng nghiên cứu chuyên sâu về hiện tượng kỳ lạ này và họ gọi nó là Placebo Effects hay Hiệu Ứng Giả Dược –––––––––––– Mục Lục –––––––––––– (00:00) Mở Đầu (00:49) Khởi Đầu Của Tên Gọi (02:42) Nguồn Gốc Của Placebo (04:59) Ảnh Hưởng Của Hiệu Ứng –––––––––––– Ủng Hộ ––––––––––––– Ủng hộ E/N qua Patreon http://www.patreon.com/ExplainNation Qua MoMo http://bit.ly/ENMoMo Trở thành thành viên của Channel https://www.youtube.com/ExplainNation/join ––––––––––––––––––––––––––––––– ♫ Music by Epidemic Sound https://bit.ly/ENEpideSound ––––––––––––––––––––––––––––––– © Explain Nation https://www.youtube.com/ExplainNation
Our guests today are Mike Guadango and Alex Brooker. Mike and Alex (“Brooker”) met when Alex interned for Mike at DeFranco’s gym a decade ago, and they now have a podcast together, “The Mike and Brooker Show”, in addition to their coaching careers. Alex is the owner and operator of Pathfinder, a private training service focused on performance psychology and physical preparation for professional athletes. In addition to traditional schooling, Alex is now pursuing his PhD in Self-Hypnosis at the University of Bern. Mike is currently a Coach, Writer & Owner at Freak Strength. He has been mentored by coaching greats such as Buddy Morris and James Smith, and started his career working at DeFranco’s gym. Mike has coached levels of athletes from many different professional sports to Olympic medalists to pre-pubescent athletes, as well as consulting for high caliber athletes and coaches worldwide. As an ever-optimistic individual, it’s important for me to have conversations with those who have a different way of looking at what actually works in the world of sports performance. In the coaching world, it is extremely easy to have worked with an athlete who has achieved a high result, and then rationalize the factors that led to their success. It is very easy for us all as coaches to think of our own training as highly optimal, but a question to ask is how often and effectively we truly challenge our reasoning? In looking at training closely, it is helpful to fully understand the power of belief, as well as placebo effects in not only training, but also pain science and rehabilitation. Understanding human adaptation to training and rehab stimulus requires, not only an understanding of the body, but also of the mind. In today’s podcast, Mike and Alex “Brooker” talk about how they have evolved themselves as coaches, moving into the realms of hypnosis/mental training, acupuncture and rehabilitation. We spend a lot of time chatting about the power of belief and the ability of the mind to supercede a “poor” training program, and how the fundamentals of adaptation style can be seen in rudimentary rehab. Finally, Mike, Brooker and I spend some time discussing some training points such as play, competition in training, and training transfer. This was a fun show with speakers of 3 clearly diverse viewpoints, which always makes for great discussion. Today’s episode is brought to you by SimpliFaster and Lost Empire Herbs. View more podcast episodes at the podcast homepage. Head to www.lostempireherbs.com/justfly for 15% off of your purchase! Timestamps and Main Points 6:15 Mike and Brooker’s moves into more alternative forms of human performance, and a philosophy of when to move on from hair splitting in strength training methods 15:00 Thoughts on a system that prioritizes play and autonomy as a substantial shift in a positive direction towards the sports performance industry 32:30 Thoughts on whether or not gym training should carry mental, emotional and physical elements of what is required of a person in their sport 46:25 How and why our interventions in strength, performance or pain reduction actually work, and how much we really know about these mechanisms 55:55 How Mike and Brooker diverted from the traditional routes of strength, performance and data in athlete performance training 1:05:30 More on Mike and Brooker’s “skill stacking” in their human performance pursuits 1:13:10 Mike and Brooker’s use of high-transference exercises to athletic performance 1:15:30 In 10-15 years, where do Mike and Brooker picture themselves “Even if there is a difference between the two (exercises), and transferability, how much of a difference is it really?” “15% of who you are as an athlete, you actually have some type of control over” “The more high talented people you work with, the room to improve them in the gym gets smaller,
Hi everyone! In this episode we delve a little deeper into the placebo effect and it's lessor known evil twin, a weird case of Covid antibodies and a secret cat. Enjoy!
Can your doctors' beliefs about the efficacy of a treatment affect how you experience pain? In episode 65, we’re joined by Luke Chang from the Department of Psychological & Brain Sciences at Dartmouth College. He talks with us about his research into socially transmitted placebo effects, through which patients can pick up on subtle facial cues that reveal their doctor's beliefs about how effective a treatment will be.
Remember friends and relatives here and not here while working in the kitchen. Jeanne Marie Beaumont holds an MFA in Writing from Columbia University and is the author of four books of poetry. Her first, Placebo Effects, was selected by William Matthews as a winner in the National Poetry Series and published by W.W. Norton in 1997. Her poems have been included in more than three dozen anthologies and textbooks. She won the 2009 Dana Award for Poetry, and also The Greensboro Review literary award for poetry in 2003 and was a finalist for the Writers’ League of Texas Book Award, 2011. From 1992 to 2000, she was co-editor of the literary magazine American Letters & Commentary. She currently teaches at The Unterberg Poetry Center of the 92nd Street Y in Manhattan. “When I Am in the Kitchen” first appeared in Burning of the Three Fires BOA Editions.
♡ SUPPORT THIS PODCAST ♡ In today's episode, Gina draws from the work of Dr. Joe Dispenza to discuss the power of the placebo effect and how it can help with anxiety. There has been much scientific study elucidating the placebo effect and Gina reviews key studies and how you can empower yourself with this knowledge today. Start listening with a 30-day Audible trial and your first audiobook plus two Audible Originals are free. Visit audible.com/coachgina or text coachgina to 500500. Brian Johnson episode https://www.theanxietycoachespodcast.com/episodes/195-philosophers-notes-brian-johnson-shres-his-wisdom-on-anxiety To learn more go to: http://www.theanxietycoachespodcast.com Join our Group Coaching Full or Mini Membership Program Learn more about our One-on-One Coaching What is anxiety? Quote: The greatest force in the human body is the natural drive of the body to heal itself - but that force in not independent of the belief system. Everything begins with belief. What we believe is the most powerful option of all. -Norman Cousins
♡ SUPPORT THIS PODCAST ♡ In today's episode, Gina draws from the work of Dr. Joe Dispenza to discuss the power of the placebo effect and how it can help with anxiety. There has been much scientific study elucidating the placebo effect and Gina reviews key studies and how you can empower yourself with this knowledge today. Start listening with a 30-day Audible trial and your first audiobook plus two Audible Originals are free. Visit audible.com/coachgina or text coachgina to 500500. Brian Johnson episode https://www.theanxietycoachespodcast.com/episodes/195-philosophers-notes-brian-johnson-shres-his-wisdom-on-anxiety To learn more go to: http://www.theanxietycoachespodcast.com Join our Group Coaching Full or Mini Membership Program Learn more about our One-on-One Coaching What is anxiety? Quote: The greatest force in the human body is the natural drive of the body to heal itself - but that force in not independent of the belief system. Everything begins with belief. What we believe is the most powerful option of all. -Norman Cousins
In this podcast, Cody Gough and Ashley Hamer discuss the following stories to help you get smarter and learn something new in just a few minutes: Your DNA Could Determine How Easily You're Fooled By Placebos What's the Emergency Fund Plan for You? For more budgeting guidance, check out "The Total Money Makeover: Classic Edition: A Proven Plan for Financial Fitness" by Dave Ramsey. Our Favorite Ongoing Science Debates Follow Curiosity Daily on your favorite podcast app to learn something new every day withCody Gough andAshley Hamer. Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers. See omnystudio.com/listener for privacy information.
Com certeza você já ouviu falar do fenômeno Placebo, um termo comumente usado na área da saúde. É fascinante ver os pacientes melhorarem com esse fenômeno. Como que a ciência explica isso? Quais são seus mecanismos? E a questão ética que envolve esse fenômeno? Seria a Fisioterapia o melhor dos placebos? Segura ai! Esse podcast é parte do canal Fisio na Pauta. Nesse canal, assuntos relevantes serão discutidos usando a ciência e o ceticismo como pedras fundamentais. Minha intenção é oferecer informação sobre saúde, ciência, reabilitação e claro… Fisioterapia! O Fisio na Pauta Podcast é uma produção independente, elaborado por um fisioterapeuta disposto a disseminar conhecimento em prol da evolução da ciência da Fisioterapia. O conteúdo desse programa é meramente informativo e não deve ser utilizado como conselho médico, uma vez que o conteúdo científico está constantemente evoluindo. Em caso de sintomas e/ou dúvidas, recomendo procurar um profissional da área da saúde. As informações e opiniões expressas nesse programa são de inteira responsabilidade de seus autores, não correspondendo necessariamente ao ponto de vista dos colaboradores do canal. Você pode acompanhar o Fisio na Pauta Podcast das seguintes maneiras: website: www.fisionapauta.com.br email: contato@fisionapauta.com.br Twitter: @fisionapauta Facebook: @canalfisionapauta Instagram: fisionapauta Deixe seu comentário no iTunes! Quer colaborar e apoiar o canal Fisio na Pauta? Acesse: http://www.fisionapauta.com.br/apoie/ Ouça, divulgue, compartilhe! Músicas: DJ Cam Quartet – Rebirth of Coll – https://www.youtube.com/watch?v=oU0ZmbBY9QI John Butler – Ocean – https://www.youtube.com/watch?v=jdYJf_ybyVo NORAK – Placebo – https://www.youtube.com/watch?v=o-xhkVZ0MMM Mo’ Horizons - Yes Baby Yes - https://www.youtube.com/watch?v=6fNDzsi8j3o Cyndi Cresswell Cook - Placebo Effect - https://www.youtube.com/watch?v=EYiMVvYeJqg Referência bibliográficas: Beedie, C., Whyte, G., Lane, A. M., Cohen, E., Raglin, J., Hurst, P., ... & Foad, A. (2017). ‘Caution, this treatment is a placebo. It might work, but it might not’: why emerging mechanistic evidence for placebo effects does not legitimise complementary and alternative medicines in sport. Jensen, K. B., Kaptchuk, T. J., Chen, X., Kirsch, I., Ingvar, M., Gollub, R. L., & Kong, J. (2014). A neural mechanism for nonconscious activation of conditioned placebo and nocebo responses. Cerebral cortex, 25(10), 3903-3910. Benedetti, F., & Dogue, S. (2015). Different placebos, different mechanisms, different outcomes: lessons for clinical trials. PLoS One, 10(11), e0140967. Benedetti, F., Mayberg, H. S., Wager, T. D., Stohler, C. S., & Zubieta, J. K. (2005). Neurobiological mechanisms of the placebo effect. Journal of Neuroscience, 25(45), 10390-10402. Stack, E. (2006). Physiotherapy: the ultimate placebo. Physiotherapy research international, 11(3), 127-128. Bystad, M., Bystad, C., & Wynn, R. (2015). How can placebo effects best be applied in clinical practice? A narrative review. Psychology research and behavior management, 8, 41. McDonald, C. J., Mazzuca, S. A., & McCabe, G. P. (1983). How much of the placebo ‘effect’is really statistical regression?. Statistics in medicine, 2(4), 417-427. Manchikanti, L., Giordano, J., Fellows, B., & Hirsch, J. A. (2011). Placebo and nocebo in interventional pain management: A friend or a foe-or simply foes. Pain Physician, 14(2), E157-E175. Reicherts, P., Gerdes, A. B., Pauli, P., & Wieser, M. J. (2016). Psychological placebo and nocebo effects on pain rely on expectation and previous experience. The Journal of Pain, 17(2), 203-214. Miller, F. G., & Colloca, L. (2009). The legitimacy of placebo treatments in clinical practice: evidence and ethics. The American Journal of Bioethics, 9(12), 39-47. LORENTZ, Eric. (2015). The Placebo Effect: A Neurobiological Review. USURJ: University of Saskatchewan Undergraduate Research Journal, [S.l.], v. 2, n. 1. Campbell, G. (Brain Science Podcast). (2018, April 01). Neurobiology of Placebos: Interview with Dr. Fabrizio Benedetti, author of Placebo Effects: Understanding the Mechanisms in Health and Disease. FREE Audio mp3. Campbell, G. (Brain Science Podcast). (2018, April 01). Placebo Research Update with Fabrizio Benedetti: Interview with Dr. Fabrizio Benedetti, author of Placebo Effects and The Patient's Brain. FREE Audio mp3. Foto da vitrine: photography: https://visualmeditation.co/placebo-and-nocebo-effects-how-your-thoughts-influence-your-health/
Com certeza você já ouviu falar do fenômeno Placebo, um termo comumente usado na área da saúde. É fascinante ver os pacientes melhorarem com esse fenômeno. Como que a ciência explica isso? Quais são seus mecanismos? E a questão ética que envolve esse fenômeno? Seria a Fisioterapia o melhor dos placebos? Segura ai! Esse podcast é parte do canal Fisio na Pauta. Nesse canal, assuntos relevantes serão discutidos usando a ciência e o ceticismo como pedras fundamentais. Minha intenção é oferecer informação sobre saúde, ciência, reabilitação e claro… Fisioterapia! O Fisio na Pauta Podcast é uma produção independente, elaborado por um fisioterapeuta disposto a disseminar conhecimento em prol da evolução da ciência da Fisioterapia. O conteúdo desse programa é meramente informativo e não deve ser utilizado como conselho médico, uma vez que o conteúdo científico está constantemente evoluindo. Em caso de sintomas e/ou dúvidas, recomendo procurar um profissional da área da saúde. As informações e opiniões expressas nesse programa são de inteira responsabilidade de seus autores, não correspondendo necessariamente ao ponto de vista dos colaboradores do canal. Você pode acompanhar o Fisio na Pauta Podcast das seguintes maneiras: website: www.fisionapauta.com.br email: contato@fisionapauta.com.br Twitter: @fisionapauta Facebook: @canalfisionapauta Instagram: fisionapauta Deixe seu comentário no iTunes! Quer colaborar e apoiar o canal Fisio na Pauta? Acesse: http://www.fisionapauta.com.br/apoie/ Ouça, divulgue, compartilhe! Músicas: DJ Cam Quartet – Rebirth of Coll – https://www.youtube.com/watch?v=oU0ZmbBY9QI John Butler – Ocean – https://www.youtube.com/watch?v=jdYJf_ybyVo NORAK – Placebo – https://www.youtube.com/watch?v=o-xhkVZ0MMM Mo’ Horizons - Yes Baby Yes - https://www.youtube.com/watch?v=6fNDzsi8j3o Cyndi Cresswell Cook - Placebo Effect - https://www.youtube.com/watch?v=EYiMVvYeJqg Referência bibliográficas: Beedie, C., Whyte, G., Lane, A. M., Cohen, E., Raglin, J., Hurst, P., ... & Foad, A. (2017). ‘Caution, this treatment is a placebo. It might work, but it might not’: why emerging mechanistic evidence for placebo effects does not legitimise complementary and alternative medicines in sport. Jensen, K. B., Kaptchuk, T. J., Chen, X., Kirsch, I., Ingvar, M., Gollub, R. L., & Kong, J. (2014). A neural mechanism for nonconscious activation of conditioned placebo and nocebo responses. Cerebral cortex, 25(10), 3903-3910. Benedetti, F., & Dogue, S. (2015). Different placebos, different mechanisms, different outcomes: lessons for clinical trials. PLoS One, 10(11), e0140967. Benedetti, F., Mayberg, H. S., Wager, T. D., Stohler, C. S., & Zubieta, J. K. (2005). Neurobiological mechanisms of the placebo effect. Journal of Neuroscience, 25(45), 10390-10402. Stack, E. (2006). Physiotherapy: the ultimate placebo. Physiotherapy research international, 11(3), 127-128. Bystad, M., Bystad, C., & Wynn, R. (2015). How can placebo effects best be applied in clinical practice? A narrative review. Psychology research and behavior management, 8, 41. McDonald, C. J., Mazzuca, S. A., & McCabe, G. P. (1983). How much of the placebo ‘effect’is really statistical regression?. Statistics in medicine, 2(4), 417-427. Manchikanti, L., Giordano, J., Fellows, B., & Hirsch, J. A. (2011). Placebo and nocebo in interventional pain management: A friend or a foe-or simply foes. Pain Physician, 14(2), E157-E175. Reicherts, P., Gerdes, A. B., Pauli, P., & Wieser, M. J. (2016). Psychological placebo and nocebo effects on pain rely on expectation and previous experience. The Journal of Pain, 17(2), 203-214. Miller, F. G., & Colloca, L. (2009). The legitimacy of placebo treatments in clinical practice: evidence and ethics. The American Journal of Bioethics, 9(12), 39-47. LORENTZ, Eric. (2015). The Placebo Effect: A Neurobiological Review. USURJ: University of Saskatchewan Undergraduate Research Journal, [S.l.], v. 2, n. 1. Campbell, G. (Brain Science Podcast). (2018, April 01). Neurobiology of Placebos: Interview with Dr. Fabrizio Benedetti, author of Placebo Effects: Understanding the Mechanisms in Health and Disease. FREE Audio mp3. Campbell, G. (Brain Science Podcast). (2018, April 01). Placebo Research Update with Fabrizio Benedetti: Interview with Dr. Fabrizio Benedetti, author of Placebo Effects and The Patient's Brain. FREE Audio mp3. Foto da vitrine: photography: https://visualmeditation.co/placebo-and-nocebo-effects-how-your-thoughts-influence-your-health/
Do we really need to produce new content in L&D, or should we just teach people how to learn for themselves? How would we then measure success, or demonstrate our output to the board? Ben Betts of HT2 Labs joins Justin and Owen to discuss the role of curation in L&D on this week's show. If you want to join in the conversation, you'll find us all on Twitter: @owenferguson, @bbetts and @writerjustin. You can also tweet @GoodPractice or @GoodpracticeAus. If you'd like to find out more about our upcoming events, blogs and whitepapers, visit goodpractice.com. The articles Owen discusses are: The Placebo Effect is a Lie: https://medium.com/the-mission/the-placebo-effect-is-a-lie-61a26df35aae The Weird Power of the Placebo Effect, Explained: https://www.vox.com/science-and-health/2017/7/7/15792188/placebo-effect-explained Placebo Effects are Weak: Regression to the Mean is the Main Reason Ineffective Treatments Appear to Work: http://www.dcscience.net/2015/12/11/placebo-effects-are-weak-regression-to-the-mean-is-the-main-reason-ineffective-treatments-appear-to-work/
Placebo Effects work by certain RULES that we can LEARN and USE for our benefit
Lon Kilgore, from the Kilgore Academy, joins us today.Lon has a Ph.D. in Anatomy and Physiology and is an accomplished weightlifting and athletic coach. You can read his full CV, including his published research, here. He has competed in powerlifting, the first CrossFit Total event, wrestling, and rowing. In addition to this, he is the developer of the Basic Barbell Training and Exercise Science specialty seminars for CrossFit. He is a military veteran and currently runs the Kilgore Academy. Lon has authored many bestselling books including Starting Strength, Fit, Practical Programming for Strength Training, and Anatomy Without a Scalpel.Today’s episode is focused heavily on education for coaches. We spoke with Lon for two hours in this episode! We talk about where the best education in fitness can be found, how do you do it, and where do you learn. We also talk about certifications, the Kilgore Academy, and more!The second hour of the episode covers a discussion of Academic versus Commercial training for Fitness instructors. In this hour we discuss the pros and cons of both and Lon’s experience in each track.Timeline:11:06 Getting Started in Fitness19:20 Practical Programming28:07 Academia vs Practice32:49 Applied Fitness Research40:53 Publishing Fitness Papers45:53 Good Research vs Bad Research51:04 The Most Up to Date Science54:13 Fitness Advice Red Flags56:34 Placebo Effects of Training60:09 Experimenting on Clients63:37 Kilgore Academy Online Courses67:02 Academic vs. Commercial Training72:21 When to Pursue Academic Education74:24 Starting a Fitness Career84:08 Technology’s Role in Education89:01 More on the Kilgore Academy100:28 Replacing Academic Education103:00 Lon’s Creative Side110:49 Never Stop LearningContact:Lon Kilgore: lon@lonkilgore.com https://www.facebook.com/lon.kilgore Links: http://lonkilgore.com/ http://www.kilgoreacademy.com/ http://www.itcamefromasciencejournal.com/
Is astrology good or bad? Links Mentioned: Astrology on Wikipedia Placebo Effect realgoodbadshow on Twitter
Ted Kaptchuk is a professor of medicine at Harvard Medical School and director of the Program in Placebo Studies and the Therapeutic Encounter at Beth Israel Deaconess Medical Center. Stephen Morrissey, the interviewer, is the Managing Editor of the Journal. T.J. Kaptchuk and F.G. Miller. Placebo Effects in Medicine. N Engl J Med 2015;373:8-9.
Placebo EffectsHow would you feel if you knew you could take a single pill that could dramatically transform your happiness and levels of personal success?Belief Global Founder, Rich Smith, explains exactly how you can use the power of placebo's to achieve incredible results in your own life. With Phil Keeler, Belief Radio Presenter. FOLLOW US... @beliefglobal on Twitter, Facebook and YouTube REMEMBER... Listen to FREE inspirational podcasts at Belief Radio, our whole archive on iTunes and read motivational books and downloads by top performance coach Rich Smith. ACCELERATE IMPROVEMENT... Call us on +44 (0) 208 688 0968 and email to info@beliefglobal.com
We have a good understanding of placebo effects in adults, but how about children? The current literature suggests some significant differences in the way children respond to placebos, but more research is needed to understand these differences properly. In this podcast, Katja Weimer from University Hospital Tübingen explains why it's difficult to study placebo effects in children and how we might overcome these difficulties. See acast.com/privacy for privacy and opt-out information.
Background and Objective: A recent Cochrane review on placebo interventions for all kinds of conditions found that `physical placebos' (which included sham acupuncture) were associated with larger effects over no-treatment control groups than `pharmacological placebos'. We re-analyzed the data from this review to investigate whether effects associated with sham acupuncture differed from those of other `physical placebos'. Methods: All trials included in the Cochrane review as investigating `physical placebos' were classified as investigating either (sham) acupuncture or other physical placebos. The latter group was further subclassified into groups of similar interventions. Data from the Cochrane review were re-entered into the RevMan 5 software for meta-analysis. The primary analysis was a random-effects analysis of trials reporting continuous outcomes of trials that used either sham acupuncture or other physical placebos. Results: Out of a total of 61 trials which reported a continuous outcome measure, 19 compared sham acupuncture and 42 compared other physical placebos with a no-treatment control group. The trials re-analyzed were highly heterogeneous regarding patients, interventions and outcomes measured. The pooled standardized mean difference was -0.41 (95% confidence interval -0.56, -0.24) between sham acupuncture and no treatment and -0.26 (95% CI -0.37, -0.15) between other physical placebos and no treatment (p value for subgroup differences = 0.007). Significant differences were also observed between subgroups of other physical placebos. Conclusion: Due to the heterogeneity of the trials included and the indirect comparison our results must be interpreted with caution. Still, they suggest that sham acupuncture interventions might, on average, be associated with larger effects than pharmacological and other physical placebos.
"Worms worms worms" by Lachlan Whatmore "Science Trivia" hosted by Victoria Bond. Contributors are Lachlan Whatmore, Ian Woolf and Patrick Rubie "The number 30" by Patrick Rubie News by Victoria Bond and Ian Woolf -Evolutionary Leap -Hadron Collider -Placebo Effects -Global Melting Music: Tom Glazer - "What makes the weather" "It's a Scientific Fact" Presented by Lachlan Whatmore Panelled by Ian Woolf Produced by Patrick Rubie
Background: Recent reviews on placebo effects in clinical trials suggest that objective changes following placebo treatments may not exist or, at least, have been considerably overestimated. However, the possibility that yet unidentified subsets of parameters are responsive to placebo treatments has not been taken into account. Therefore, the aim of the present study is to examine the effects of placebo treatments on objectively measured outcome parameters by specifically focusing on peripheral disease processes. Methods: An initial dataset was collected from a MEDLINE search for placebo-controlled, randomized clinical trials. Trials with stable disease conditions were identified, and the effects of placebo treatments on peripheral outcome parameters were estimated by the changes from baseline in the placebo groups. An explorative data analysis was conducted in order to identify parameter classes with differential responsiveness to placebo treatments. A subgroup meta-analysis of a second dataset was performed to test whether the preliminary classification would also apply to placebo effects derived from the comparison of placebo groups with untreated control groups. Results: The explorative analysis of outcome parameters and strength of placebo effects yielded a classification into responsive "physical" versus non-responsive "biochemical" parameters. In total, 50% of trials measuring physical parameters showed significant placebo effects, compared with 6% of trials measuring biochemical parameters. A subgroup meta-analysis substantiated the differential response ( physical parameters: n = 14, Hedges' pooled effect size g = 0.34, 95% CI 0.22 to 0.46; biochemical parameters: n = 15, g = 0.03, 95% CI - 0.04 to 0.10). The subanalysis of the second dataset supported the classification and revealed a significant improvement for physical parameters ( n = 20, g = 0.22, 95% CI 0.07 to 0.36) and a deterioration for biochemical parameters ( n = 6, g = - 0.17, 95% CI - 0.31 to - 0.02). Conclusion: The results suggest that placebo interventions can improve physical disease processes of peripheral organs more easily and effectively than biochemical processes. This differential response offers a good starting point for theoretical considerations on possible mediating mechanisms, and for future investigations in this field.
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