Podcasts about predictors

Why Men Lie to Look Good (And Women Lie to Protect) | FT: Brian ReevsCONNECT WITH CHARLENEOn Instagram @mscharlenebyars([https://www.instagram.com/mscharlenebyars]On YouTube @chosentraining(https://www.youtube.com/@lovestorieswithcharlenebyars))Work with me HERE([https://charlenebyars.com/](https://charlenebyars.com/))CONNECT WITH BRIANOn Instagram:Relationship coach Brian Reeves explains why men change only when they risk losing their partner, and the real work behind lasting love.Timestamps:00:00 — Intro: Meet Brian Reeves, Former Air Force Captain & Relationship Coach03:02 — Married to Therapist Sylvia Kugazian: 11 Years Together06:59 — Why It Took Seven Years to "Get Good" at Being With Each Other08:00 — The Men's Retreat Story: Seeing Brian Struggle Was the Turning Point11:00 — Why Men and Women Lie for Different Reasons16:05 — Embracing Messiness Without Excusing Impact18:28 — The Defensive Trap: "You Shouldn't Feel That Way"23:37 — What Brian Had to Confront Before Real Intimacy Was Possible27:00 — The Two Core Male Wounds: "I'm a Screwup" and "You Don't See My Heart"30:46 — Terry Real's Concept: Disconnection as the Original Wound32:39 — Brian's Military Background and Early Relational Disasters36:00 — Why Women's Anger at Men Is Necessary for Change38:43 — The Boundary That Actually Changes a Man43:40 — Charlene's Story: Making a Stand, Not a Threat49:03 — What Emotional Maturity Actually Looks Like52:00 — Why Emotions Travel in Pairs (Joy and Grief, Anger and Enthusiasm)54:30 — How Suppressing "Unwanted" Emotions Backfires Into Addiction56:00 — Safety Differences: Why Women Experience Fear Differently58:45 — Advice for Someone Stuck in an Unhealthy Pattern1:00:00 — The Predictor of Relationship Success: Willingness to Lean In1:03:00 — What to Do If Your Partner Won't Get Support1:04:00 — Where to Find Brian Reeves + His Elevate Coaching Program1:05:00 — Closing Thoughts: Doing the Work Creates the GapThe conversation closes with encouragement for anyone doing this work solo: growth creates a gap your partner will eventually have to choose to close, or not.

Psychological distress has been associated with inferior outcomes after major joint arthroplasty, but its impact on outcomes after total ankle arthroplasty (TAA) remains unclear. The main aim of this study was to investigate whether patients reporting anxiety or depression before TAA surgery had inferior outcomes 1 year after surgery. In conclusion, Preoperative self-reported anxiety or depression was common among patients undergoing TAA and was associated with worse symptoms before surgery. However, the reporting of such symptoms did not appear to limit postoperative improvement in patient-reported outcomes at 12 months. Among patients reporting anxiety/depression preoperatively, approximately two-thirds no longer reported anxiety/depression at 12 months. Click here to read the article

Send us Fan MailDr Daneshvar is an associate professor at Harvard Medical School, Chair of physical medicine and Rehabilitation at Spaulding Rehabilitation, and Co-Director of Sports Concussion at Mass General Brigham, whilst also a long-time collaborator with the Boston University CTE Centre. Lastly, Dr Daneshvar earned the National Neurotrauma Society's 2024 Rising Star Award, whilst publishing more than 100 papers and being cited over 18,000 times by his academic peers. One of those articles is “Prevalence of chronic traumatic encephalopathy at death in National Football League players: retrospective population-based cohort study, 2008-21” The topic of today's conversation. 01:15 - Journey into Neurosciences and Brain Injury 02:50 – What is and Difference Between Concussion and CTE05:16 -  “Prevalence of Chronic Traumatic Encephalopathy at Death in National Football League Players: Retrospective Population-Based Cohort Study, 2008-21” What are the major findings? How was it conducted…. Etc09:10 – Extrapolation of CTE in Populations & Correlation Against Death Certificates12:13 – Stage's of CTE15:10 - Accelerometer Data as a Predictor of CTE vs Career Length 18:10 - Significant Challenges in Conducting Studies Around CTE23:10 – Risk Reduction 27:40 - How Can we Help Support Dr Daneshvar Research Dr Daniel DaneshvarGoogle Scholar: https://scholar.google.com/citations?user=YF2omqkAAAAJ&hl=en Prevalence of chronic traumatic encephalopathy at death in National Football League players: retrospective population-based cohort study, 2008-21 : https://www.bmj.com/content/394/bmj-2026-100418

This is the Weight and Healthcare newsletter! If you like what you are reading, please consider subscribing and/or sharing!In Part 1 we discussed the basics of hernia repair for higher-weight people. In part 3 we'll discuss the options for fighting BMI-based denials for hernia care. While I take the stance that people of all sizes deserve equitable care, in Part 2, I want to talk about the issues with these weight loss recommendations (this is a piece I've been meaning to write for a while so I'm incuding it in this series, but know that this isn't just about hernia repair but about anytime weight loss is recommended or required for a patient to be “optimized” for surgery.) Today we're going to look at it from the perspective of someone who agrees with these recommendations (which I d not) and/or of somene who is so desperate for care that they are willing to try to pay the weight loss ransom (which is a valid choice, but one that patients should never be coerced into making by a healthcare system that holds their care hostage.) Even in these circumstances, there are multiple issues with these weight loss recommendations including feasibility, side effects, and long-term prognosis.Feasibility and Side EffectsThe first question to ask is the feasibility of the requirement. “Optimization” for surgery doesn't happen in a vacuum and it doesn't matter if something would make the patient's surgery easier or improve their outcomes if it is not possible and/or if it harms the patient more than it helps them. Despite this, the feasibility/likelihood of the patient experiencing the required weight loss is, in my experience, far too often not discussed or even considered.I have met with patients who were told they needed to lose 40% of their body weight whose surgeon told them to eat less and exercise more. This is an “intervention” for which about a century of research has found the likelihood of losing even 5% of body weight is quite low and the likelihood of maintaining it is incredibly small (though we'll get to that.) The doctor might as well have told the patient to grow 6 inches to change their BMI sufficiently.Enter GLP-1s. Here again we're seeing patients being prescribed these drugs not based on the drugs' actual capacity to create (at least short term) the required weight loss but based on the sincerely held personal belief of the provider that any amount of weight can be lost with these drugs.In the recent research article that Angela Meadows, Louise Adams, and I published on GLP-1s for weight loss, we included tables in the supplemental materials that include information for all of the phase 3, placebo-controlled trials of GLP1-s for weight loss. One of the reasons I am glad these tables are out in the world is so they can be used in these discussions.As the tables show, about half of people don't ever reach average weight loss in these trials with around 5-15% failing to lose even 5%. For semaglutide, the STEP 1 trial only looked at weight loss up to 15%, and 49.5% of the subjects failed to lose even 15% of body weight over 68 weeks and in the STEP 3 trial, even when combined with a restrictive diet, 64.3% of subjects failed to lose even 20% of their body weight over 68 weeks. For tirzepatid, the SURMOUNT 1 trial included weight loss up to 25% and 63.8% of the people on the maximum dose (15mg) failed to lose even 25% of their body weight over 72 weeks. In the 2-year weight loss analysis of the SELECT trial ( Ryan et al., 2024) 95.1% of patients failed to lose 20% of their body weight, average weight loss was down to 10%, and at four years the study had lost 89.5% of participants! Other studies showed significant loss of muscle mass as part of the weight loss.You can find the tables here in the supplemental materials. If you are being told to use GLP-1s to qualify for healthcare I also have a case study here that offers more information and some specific scripting that you can use.Then there is the recommendation for weight loss surgery. This is a surgery in which a healthy, correctly functioning digestive system is surgically manipulated into what would otherwise be considered a disease state in order to force restriction and produce weight loss. It is a very serious surgery with the potential for very serious side effects that can have significant negative impact on long-term quality of life and even be fatal. I wrote about the basics of these surgeries here. I also have a series about weight loss surgery and long-term quality of life in which researchers admit sparse and low-quality evidence, and that in multiple studies health-related quality of life was the same between those who had surgery and those who didn't.At the bare minimum, giving the patient correct information about the likelihood of these surguries of actually leading to the weight loss that is being demanded in order for the patient to get the surgery they actually need is incredibly important when the patient is being refused a surgery that they need but recommended to undergo a surgery that alters an entire body system in a way that is, by and large, irreversible with potentially life-altering and even fatal side effects. A 2022 study called “Predictors for weight loss after Roux-en-Y gastric bypass: the trend and associated factors for weight loss” by Eghbali explains that while most people expect to lose more than 70% of the “excess weight” in reality the mean total weight loss is about 32% at 1-2 years. So, even if the patient is willing to have this surgery (and risk the significant side effects) and even if they could reach the mean total weight loss, that would still not necessarily be enough weight loss for the patient to qualify for the surgery they actually need/want.Medical interventions must be evidence-based and wishin' and hopin' and thinkin' and prayin' that all higher-weight patients will be outliers and experience more weight loss than the research suggests is likely (even in the short term) so that they can be seen as worthy of surgery is not ethical, evidence-based medicine.Long-Term OutcomesWe know that the vast majority of weight loss attempts end in weight regain and that regain with GLP-1s has been shown to be even faster than with lifestyle interventions. Guidelines around weight loss for hernia repair typically brush this off with simple admonitions that amount to “don't do that.” Given that intentional weight loss changes the body physiologically to induce weight regain, using the equivalent of “doctor, it hurts when I do this….well don't do that” here again falls seriously short of ethical, evidence-based medicine.Even if someone believes that people could lose any amount of weight and maintain that weight loss, medicine must be practiced in the context of reality. That means understanding the risks of delaying the surgery while the patient attempts weight loss that research shows is unlikely to unlikely to ever happen, and considering the risks of weight regain on the surgical repair, which research shows is highly likely to happen. This is especially important given the existence of research for other procedures that finds that weight loss prior to surgery, including through weight loss surgery, does not improve outcomes.The sad reality, which is all too common, is that there isn't enough research about hernia repair when it comes to higher-weight people. And as long as the healthcare system is comfortable allowing higher-weight patients to suffer and die unless or until they can comply with a directive to lose weight, those with power, privilege, and leverage to make change will need to do whatever can be done to fund and conduct the research that is needed so that people of all sizes can have equitable care.In part 3 we'll discuss the options for patients who are dealing with BMI-Based Denials for hernia care.This month's online workshop is Weight-Inclusive Sleep Apnea Management with special guest Dr. Lisa Erlanger! There is a pay-what-you-can option so money isn't a barrier and all registrants will receive a video. Details and registration are here! If you appreciate the work I do here, you can support my ability to do it by becoming a free or paid subscriber!Liked the piece? Share the piece!More researchThe Research PostMore resourcesThe Resource Post*Note on language: I use “fat” as a neutral descriptor as used by the fat activist community, I use “ob*se” and “overw*ight” to acknowledge that these are terms that were created to medicalize and pathologize fat bodies, with roots in racism and specifically anti-Blackness. Please read Sabrina Strings' Fearing the Black Body – the Racial Origins of Fat Phobia and Da'Shaun Harrison's Belly of the Beast: The Politics of Anti-Fatness as Anti-Blackness for more on this. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

The TalkDoc & Co. explore what happens to your brain during a conflict. Those “flooding,” moments in conflict are challenging…the prefrontal cortex goes offline and the sympathetic nervous system triggers fight, flight, or freeze, leading to freezing, blanking out, or saying things you don't mean. The hosts share examples of shutting down during confrontations, becoming cold after stressful bedtime routines, reacting sharply after triggering family interactions, and going silent after receiving serious news. They discuss research linking flooding to heart-rate spikes, rising cortisol, increased emotional reactivity, and patterns shaped by attachment, plus mirror neurons and emotional contagion that make partners absorb each other's tension. Drawing on Vygotsky, they contrast calm-brain full sentences with fight-brain fragments and overestimating what others understand. Tools include noticing flooding, naming it, taking a research-backed 20-minute pause to cool down, using agreed-upon language or code words, returning for repair, elaborating speech, and discussing these strategies outside heated moments. Music by epidemic sound. SHOW NOTES: Experts :  Gottman and Vygotsky Sources :   Arnsten, A. F. T., et al. Stress and Inflammation Target Dorsolateral Prefrontal Cortex Function: Neural Mechanisms Underlying Weakened Cognitive Control. Biological Psychiatry, 97(4), 359–371 (2024/2025). García del Castillo-López, Á., et al. (2024). Emotional Flooding in Couple Relationships: Psychosocial Aspects and Regulatory Strategies. IntechOpen. Gottman, J. M., & Gottman, J. S. (2024). The New Marriage Clinic: A Scientifically Based Marital Therapy, Updated (2nd ed.). Routledge. Hutin, M., & Tomas, F. (2025). The effect of cognitive load on linguistic fluency, lexical production, and emotional polarity: An exploratory study on self-directed French. Yearbook of the German Cognitive Linguistics Association, 13(1), 165–192. Lin, D., Zhu, T., & Wang, Y. (2024). Emotion contagion and physiological synchrony: The more intimate relationships, the more contagion of positive emotions. Physiology & Behavior, 275, 114434. Morgan, S. D., et al. (2025). Perceptions of Conflict at the Transition to Parenthood: Exploring Adult Attachment Pairings as Predictors of Emotional Flooding. Family Process, 64(3), e70057. Vygotsky, L. S. (1934/1986). Thought and Language [also translated as Thinking and Speech]. MIT Press.

Here are 3 ways to build sexual satisfaction for yourself and your relationship.    Connect with Dr. Tara https://www.luvbites.co/ Get her Book: How Do You Like It?: A Guide for Getting What You Want  

We go through some of the teams that surprise us so far in ESPN's Playoff Predictor!

Commentary by Dr. Jian'an Wang.

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning spoke with Taj Mohammed Fiyaz Chowdhry, a consultant thoracic surgeon at Burjeel Specialty Hospital, Sharjah, UAE, about uniportal robotics in the UAE. Chapters  00:00 Intro  01:02 TAVR Heart Team Decision Webinar  02:00 Oral Board AI Simulator  02:22 JANS 1, CABG MIST Randomized Trial  04:26 JANS 2, Tumor Mutational Burden Predictor  06:01 JANS 3, Dapagliflozin & Acute Kidney Injury  07:44 JANS 4, ECMO vs Mech Vent Lung Transplant  09:20 JANS 5, Right Pleuro-Pericardial Window  11:19 Video 1, MV De-Repair  12:41 Video 2, Upper Mini Pulm Art Banding  14:00 Dr. Chowdhry, UAE Uniportal Robotics  22:48 Upcoming Events  They discussed the advantages of uniportal approaches and uniportal robotics, advice for surgeons transitioning to uniportal robotics, and the differences in surgical practice between the UK and the UAE, such as insurance approval protocols. They also explored Dr. Chowdry's experience introducing a new procedure to the UAE. Joel also highlights recent JANS articles on multivessel coronary artery bypass grafting via small thoracotomy versus sternotomy, a brief report on tumor mutational burden as a predictor of immune-related adverse events in patients with advanced non-small cell lung cancer receiving immune checkpoint inhibitors, a randomized clinical trial on dapagliflozin and acute kidney injury following cardiac surgery, extracorporeal membrane oxygenation versus mechanical ventilation as bridge to lung transplant, and right pleuro-pericardial window during cardiac surgery. In addition, Joel explores mitral valve de-repair, upper ministernotomy for pulmonary artery banding, and endoscopic septal tumor resection with biatrial reconstruction. Before closing, Joel highlights upcoming events in CT surgery. JANS Items Mentioned Multivessel Coronary Artery Bypass Grafting via Small Thoracotomy Versus Sternotomy (MIST): An Investigator-Initiated, International, Open-Label, Randomised Controlled Trial Tumor Mutational Burden as a Predictor of Immune-Related Adverse Events in Patients With Advanced Non-Small Cell Lung Cancer Receiving Immune Checkpoint Inhibitors: A Brief Report Dapagliflozin and Acute Kidney Injury Following, Cardiac Surgery: A Randomized Clinical Trial Building Bridges: Extracorporeal Membrane Oxygenation Versus Mechanical Ventilation as Bridge to Lung Transplant—A Nationwide Analysis Right Pleuro-Pericardial Window During Cardiac Surgery: A Safe and Simple Technique That Decreases Postoperative Atrial Fibrillation CTSNet Content Mentioned Thinking Outside the Box: Mitral Valve De-Repair Upper Ministernotomy for Pulmonary Artery Banding: Facilitating Future Reentry Endoscopic Septal Tumor Resection With Biatrial Reconstruction Other Items Mentioned The TAVR Heart Team in 2026: Navigating the CMS Decision | CTSNet Webinar Oral Board AI Simulator CTSNet Innovation Video Competition Career Center CTSNet Events   Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

Book Alan's Business Breakthrough Session. Your first 30-minute coaching call is FREE. Learn how to prioritize success and let your quality of life become the byproduct. - https://calendly.com/alanlazaros/30-minute-breakthrough-sessionFitness is forever, it's a lifestyle. Get jacked and join the Next Level Fitness Accountability Group. This group is invite-only. Reach out to Kevin or Alan on Instagram:Kevin: https://www.instagram.com/neverquitkid/Alan: https://www.instagram.com/alazaros88/_______________________Your daily choices matter more when you see where they lead. In this episode, Kevin and Alan illuminate why time perspective is one of the strongest predictors of long-term success in health, wealth, love, and personal development. They break down the difference between living for immediate comfort and building a life your future self can respect. Kevin reflects on learning that surface-level goals alone do not create fulfillment, while Alan shares how years of disciplined habit change and coaching have reinforced a simple truth. Every repeated choice compounds.You will hear how to identify the distractions draining your time, money, and focus, calculate the real cost of small habits, and build greater self-awareness without trying to overhaul your entire life overnight. This is not about becoming perfect or removing every pleasure. It is about developing the ability to think further ahead before today's impulse sends tomorrow the bill. Your future is keeping receipts. Give it fewer bad ones._______________________Digital Asset: The Top 10 Distractions Holding You Back - https://drive.google.com/file/d/1FDUSnbitxR4E2G4hlgkpm0T-BZxLVto6/view_______________________NLU is more than a podcast. From the Next Level Dreamliner to Group Coaching, we provide tools and communities to help you grow with more clarity, consistency, and accountability.Visit our website and socials through the links below.

According to Dr. John Gottman's research, rolling your eyes at your spouse is one of the most accurate predictors of divorce because it reveals deep-seated contempt – the #1 predictor of divorce. Before the eye rolls come the negative thoughts, so guard your mind, choose honour, and bring your struggles before God to protect your marriage. _______________ We want your marriage to thrive! Learn more at http://xomarriage.com Dave and Ashley Willis spent thirteen years in full-time church ministry before devoting their work entirely toward the global mission of building stronger, Christ-centered marriages. Their marriage-related books, blogs, podcast, speaking events and media resources have reached millions of couples around the world making Dave and Ashley one of the most recognized and trusted couples in marriage ministry. Dave and Ashley partnered with XO Marriage in 2018. XO Marriage is the nation's largest marriage-focused ministry. The Willis family includes four sons and a rescue dog named "Chi Chi." When Dave and Ashley aren't writing and speaking, they love hanging out with their family, watching movies and going on long walks which is also where they develop many of their marriage ministry content ideas. Learn more about Dave & Ashley at daveandashley.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Every legal dispute comes down to a judgment call made with incomplete information — and wherever there's judgment, there are mental shortcuts quietly shaping the outcome. Host Dr. Laura Scherck Wittcoff sits down with Tricia Schafer, a full-time neutral who mediates and arbitrates cases nationwide, ahead of her TechTainment panel on implicit bias in tech-driven mediation. Together they unpack what implicit bias actually is (a normal function of the human brain, not a character flaw), why it matters most in entertainment and intellectual property disputes where there's rarely one objectively correct answer, and the practical, sometimes surprising strategies practitioners can use to design bias out of a process instead of pretending it isn't there. Tricia Schafer, Tricia Schafer Dispute Resolution PLLC: A full-time neutral and former litigator with 31 years of experience across all aspects of commercial controversies, Tricia is known for connecting people and concepts to outcomes that transcend the sum of their parts. She mediates and arbitrates cases nationwide, both privately and through the American Arbitration Association, handling commercial, real estate, health care, and consumer matters, and was recently approved as a mediator for the United States Postal Service. Based in Arizona, she also volunteers with the state court system in civil and probate matters and offers reduced-rate work to select Arizona nonprofits. She first attended TechTainment in 2024 at a friend's suggestion — arriving knowing exactly one person and leaving with roughly two dozen new friends — and has been a loyal follower since. At this year's conference, she co-presents on implicit bias with longtime friend and colleague Maria Crimi Speth, a partner at Jaburg Wilk in Phoenix and a career intellectual property litigator. What is TechTainment? TechTainment is an annual, one-day conference produced by LAIPLA, now held in partnership with the Sandra Day O'Connor College of Law at Arizona State University (ASU) at ASU's California Center in downtown Los Angeles. The conference brings together leaders in technology, entertainment, business, academia, and law to discuss the issues reshaping every industry, long before those issues become mainstream news. This year's conference: Friday, October 16, 2026, at ASU's California Center in downtown Los Angeles Tricia's panel: "Implicit Bias in Dispute Resolution and Mediation", co-presented with Maria Crimi Speth of Jaburg Wilk What implicit bias actually is: Implicit bias is not prejudice or intentional discrimination. It's a mental shortcut the brain uses to make decisions under incomplete information, limited time, or uncertainty — a normal part of being human, not a character flaw. Tricia's example makes it concrete: a Mercedes pulls into your driveway versus a beat-up pickup truck, and you've formed a judgment about the driver before you've seen them. It doesn't matter until you have to help that person resolve something that matters in their life. Why "neutral" is a noun: Tricia explains that "Neutral" is the catch-all for someone who serves as both mediator and arbitrator — a private-pay, secure way to resolve disputes outside of court. She also walks through the tradeoffs of arbitration: it's faster, it's private, it never becomes public record, and critically, you get to choose your decision-maker. File in court and you may draw a judge who spent 20 years in family law and just moved to the civil bench. Through the American Arbitration Association or another provider, you can ask for an environmental lawyer, an engineer, or a water lawyer. The cost: you pay your neutral's hourly rate, and there is almost no right to appeal. Positions versus interests, and the last orange in the house: Tricia walks through the foundational mediation exercise: two kids fighting over the last orange, and a parent's instinct to cut it in half. The better move is to ask each child why they want it — one is hungry, the other needs it for a science project — and suddenly there's a solution that makes both of them happy. As she puts it, a position is what you say you want and an interest is why you want it. Do you really want the money, or do you want the security of knowing you can keep the house? The related insight: "No" is never permanent. "No simply means I'm not going to change my position based upon the available information that I have right now." Designing bias out of the process: Tricia describes wanting software that would strip law firm letterhead off position statements before she reads them, and assign parties fake names, so she isn't forming judgments about counsel or making assumptions from the ethnicity of a surname — the same logic behind employers removing photos from resumes. She also shares a technique she uses now: she dumbs the fact pattern down, renames everyone, and spends half an hour working through the dynamic with an AI assistant. Mr. Jones and Mr. Smith fighting over a commercial building becomes Bob and Larry fighting over a pickup truck. The AI has no idea who anyone is, which is exactly the point. Where implicit bias shows up in entertainment and IP: Assumptions about how long creative work should take a human, and whether AI could do it faster. Assumptions about what a market wants and will pay for, made without consulting anyone who lives and works in that market. Confirmation bias in data used to argue for one direction over another. And the structural disadvantage facing independent creators, who often lack the resources to register, protect, or aggressively enforce their intellectual property — so their disputes get read as less significant. Tricia names the persistent disconnect between the rooms where decisions get made and the people actually watching and streaming the content. Dispute resolution is dispute prevention: One of the episode's most quotable lines, and the practical center of Tricia's advice. It's not if a dispute arises, it's when. Mediation clauses are now common in contracts — and, Tricia notes, most people don't realize those clauses are negotiable in any contract involving personal services or securing talent. "We'll mediate before we arbitrate before we litigate" means very little on its own. For how many days? What kind of mediator — an entertainment lawyer at $1,000 an hour, or a court-appointed one? In person or on Zoom? In good faith, and what does good faith mean? She points listeners to the sample clause language published by the major providers, including the AAA's ClauseBuilder tool, and notes you can even name the specific mediators you'd accept. Strategies for creators and practitioners without deep pockets: For anyone younger, newer, or under-resourced walking into a negotiation: go in without defensiveness, but look in the mirror first and ask what the other side is likely to assume about you — then stay ahead of it. On the other side of the table, for the corporations and the streamers: you know statistically what your audience does, but you don't know what's in their heads or why they're watching what they're watching. Follow the data, and also build a team of decision-makers with genuinely different perspectives. Normalizing bias instead of denying it: Tricia's hope for what people take away from her session: bias is not bad. Bias is not negative. She'd like to see the same shift the culture has already made around therapy and health tracking — from something you'd never mention to something you say out loud. Her image of what that looks like in practice: a mediator who can say "I feel like I'm getting a little biased from this room, I need to take a five-minute break." Laura's response: when you pretend it doesn't exist, it creeps in anyway. How to Get Involved Register and learn more: LAIPLA.net/techtainment Pricing: Multiple tiers are available, including discounted rates for in-house attorneys, law students, LAIPLA members, and ASU alumni Attend: The conference includes breakfast, lunch, and extensive networking opportunities Connect with Tricia: TriciaSchafer.com Connect with Small & Gutsy Website: SmallandGutsy.org Email: Laura@SmallandGutsy.org Do you know a nonprofit or social enterprise doing incredible work? Send them our way!

Torque training has become almost synonymous with low-cadence riding. But simply dropping to 60 RPM doesn't guarantee you're producing more force or creating the adaptation you're after.Coach Adam Pulford breaks down the relationship between torque, cadence, power, and force production; explains why the gym may be the best place to raise your strength ceiling; and shows where low-cadence work actually belongs in a cyclist's training year.HOSTAdam Pulford has been a CTS Coach for nearly two decades and holds a B.S. in Exercise Physiology. He's participated in and coached hundreds of athletes for endurance events all around the world.​​Free Cycling Training Assessment: https://trainright.com/cycling-training-assessment-welcome/Interested in working with a coach? Schedule a free consult: https://trainright.com/coaching/cycling/Self-coached athlete? Check out our TrainRight Membership: https://trainright.com/membership/Find more free resources here: https://trainright.com/blog/Resources:Strength Exercise F-v and P-v Profiles as Predictors of Elite Sprint-Cycling Performance - PubMedPower-time, force-time, and velocity-time curve analysis during the jump squat: impact of load - PubMed 58. HIGH INTENSITY TORQUE TRAINING CAN INCREASE CYCLING PERFORMANCEEffects of Cycling Training at Imposed Low Cadences: A Systematic Review - PubMedEffect of Cycling Cadence on Neuromuscular Function: A Systematic Review of Acute and Chronic Alterations - PMC Pro Workouts: Torque Efforts with Noemi Rueegg | EF Pro Cycling https://trainright.com/camps/

Has your journey to find pain relief hit a dead end? You've faithfully done all the scans, the exercises, the pills and procedures. But pain is still taking up your precious time and energy, and money...In this episode of The Somatic Strength Collective, Mandy Ryle uncovers a game-changing truth: fear-avoidance is the single strongest predictor of whether pain becomes chronic and disabling—far outweighing what your MRI shows or how much pain you're in.Discover why resting tight joints often backfires, how somatic movement deconditions your brain's threat alarm, and a real-life case study of overcoming fear-induced bracing. Plus, take a 5-question self-inquiry audit to see if fear-avoidance is quietly shrinking your life.⏱️ Timestamps00:07 – The Detective Trap: Why we still hurt after following the rules02:51 – The Research: Why fear-avoidance trumps MRIs & tissue damage06:59 – Confronting pain vs. the avoidance spiral11:27 – The Biopsychosocial Model: Why pain is more than physical tissue13:29 – Why hasn't your doctor or PT addressed fear-avoidance?17:31 – Client Story: Overcoming lifelong bracing & scar tissue23:25 – Subtle Avoidance: Hidden rules about bending and lifting25:35 – 5-Question Self-Inquiry: Are you trapped in fear-avoidance?29:56 – Next Steps: Download the Fear-Avoidance Audit PDF

In episode 385 of The Physical Performance Show, host Brad Beer sits down with fellow physiotherapist Lewis Craig for a lateral ankle sprain masterclass. Drawing on material the pair recently presented at a Gold Coast orthopedic evening, Brad and Lewis cover the burden and prevalence of lateral ankle sprains, the three-part clinical assessment process, key differential diagnoses, rehabilitation phases, and preventative strategies including bracing and taping. The episode explores why lateral ankle sprains — despite their reputation as a minor injury — carry a significant risk of chronic ankle instability, and why a thorough, structured assessment is essential to a smooth recovery. Brad and Lewis unpack the different ligament and tendon structures that can be involved, the red flags practitioners need to rule out, the impairment categories drawn from Jay Hertel's model of chronic ankle instability, and how rehabilitation should progress from protection through to return to sport and long-term prevention. Show Sponsor: Pogo Physio also offers online Telehealth Consultations for endurance athletes managing bone, tendon, or joint issues — book online at https://www.pogophysio.com.au. And... PILLAR Performance is leading a new frontier in the sports nutrition industry through micronutrition innovation. Their Performance Health range is designed to support the crucial hours outside of training and racing, helping athletes return to the start line in peak condition. One of their newest releases is Collagen Repair, developed in collaboration with Gelita Laboratories and featuring the clinically trialled collagen peptide TENDOFORT. For 15% off your first purchase, head to pillarperformance.shop or, for North American listeners, thefeed.com and use the code PHYSICALPERFORMANCE at checkout. Pillar Performance continues to lead the way in sports nutrition through micro-nutrition innovation, now expanding into the Performance Health range. One of their newest releases, Collagen Repair, was developed with Gelita Laboratories (Germany) using a clinically trialled collagen peptide (Tendofort) to support tendon and ligament health in conditions like hamstring tendinopathy, Achilles tendonitis, shin splints, and patellofemoral pain. Head to Pogo Physio also offers online Telehealth Consultations for endurance athletes managing bone, tendon, or joint issues — book online at https://www.pillarperformance.shop (or https://www.thefeed.com for North American listeners) and use code PHYSICALPERFORMANCE for 15% off your first purchase.   Partners / links mentioned: Ortho Tools (Cumberland Ankle Instability Tool / CAIT): mentioned in-episode as the online questionnaire resource Contact: Lewis Craig — l.craig@pogophysio.com.au In this episode, you'll hear: Episode context: Lewis Craig's return to the show after being last on around episode 109, and his progress toward finishing his Sports Masters through the University of Queensland The burden of lateral ankle sprains: why they're the most common musculoskeletal injury in sport across field and court sports, contact and non-contact alike Recurrence risk: why roughly 40% of people who sprain their ankle go on to develop chronic instability, and why the one-year mark is a key risk-reduction milestone Early predictors of chronic ankle instability: the Doherty 2016 study on single-leg landing and drop-jump testing at two weeks post-injury The three priorities of assessment: ruling out red flags and fractures, forming an accurate diagnosis, and identifying impairments Screening for fractures: mechanism of injury, the Ottawa ankle rules, weight-bearing ability, and key bony landmarks to palpate Differential diagnosis: ATFL and CFL sprains (70–80% of ankle sprains), peroneal tendon injuries, bifurcate ligament sprains, deltoid ligament tears, syndesmosis injuries, and talar dome injuries Why getting a clear mechanism of injury from the athlete is critical to an accurate diagnosis Identifying impairments: the ROAST consensus and Jay Hertel's updated model of chronic ankle instability — pathomechanical, sensory-perceptual and motor-behavioural impairments Clinical and objective testing: balance progressions, calf raise endurance and strength benchmarks, and power tests including triple hop, crossover hop and timed lateral hop The role of patient-reported outcome tools: the Cumberland Ankle Instability Tool (CAIT) and FAAM, and why they're useful for tracking progress and motivation Rehabilitation framework: protection and appropriate early loading, followed by strength, stability and mobility phases Managing specific injury types: use of moon boots, orthotics, low-dye taping and ASO ankle braces depending on the structures involved Addressing dorsiflexion loss: why regaining ankle range of motion is often one of the hardest parts of rehab, and the Torillin infographic on identifying the source of restriction Late-stage rehab and return-to-sport: hopping, change of direction, and integrating exercises into an athlete's normal training week for ongoing prevention Bracing and taping as secondary/tertiary prevention strategies to reduce recurrence Long-term consequences of poorly managed ankle sprains, including links to post-traumatic osteoarthritis and eventual ankle surgery The biggest mistake athletes make: assuming rehab is "done" once they can run, despite still having deficits in power, change of direction and stability Lewis's top tip: get every ankle sprain properly assessed, no matter how minor Quotes / takeaways: "It's just a simple lateral ankle sprain... and then someone who goes missing for months at a time." "Four out of ten people who have an ankle sprain go on to develop a chronic instability." "The better quality of the assessment, the more likely there's an accurate diagnosis." "It's really hard to sprain your ankle when it's really well strapped or with an appropriate brace." "Once someone gets running... you can run in a straight line really well and have really considerable deficits still." "Get it assessed. Understand what you've done and understand what impairments you might have." Time Stamps: 00:17 – Episode introduction and breakthrough experience 00:23 – Episode 385 introduction: lateral ankle sprain masterclass with Lewis Craig 00:50 – Sponsor: PILLAR Performance and Performance Health 01:15 – Collagen Repair: formulation, TENDOFORT and collagen health 01:44 – 15% PILLAR Performance discount with code PHYSICALPERFORMANCE 02:19 – Welcoming Lewis Craig back to the show 02:48 – Lewis's tenure at Pogo Physio and progress on his Sports Masters at UQ 03:45 – Introducing today's topic: lateral ankle sprains 04:37 – How common and burdensome are lateral ankle sprains? 05:36 – The "she'll be right" attitude and why it's changing 07:02 – Lewis's personal history with recurrent ankle sprains 08:02 – Impact on Lewis's own running and trail running 08:28 – The one-year mark and recurrence risk statistics 09:26 – Predictors of chronic ankle instability: single-leg landing and drop jump 09:53 – The Doherty 2016 study explained 10:51 – The three priorities of assessment 11:21 – Ruling out red flags and fractures 12:45 – Why assessment quality drives rehab outcomes 13:14 – Screening for fractures: mechanism, Ottawa ankle rules, bony landmarks 14:39 – Deciding on imaging: x-ray or MRI 15:06 – Differential diagnosis: the many subcategories of ankle sprain 15:35 – ATFL and CFL: the most common ligament sprains 16:35 – Peroneal tendon injuries 17:04 – Bifurcate ligament sprains 18:04 – Deltoid ligament tears with lateral ankle sprains 18:33 – Syndesmosis injuries and mechanism differences 19:31 – Clinical tests for syndesmosis 20:01 – Talar dome injuries and other easily missed diagnoses 20:30 – Why getting a clear mechanism from the athlete matters 21:29 – Identifying impairments: what it means and why it's important 22:51 – Jay Hertel's model of chronic ankle instability 23:48 – Balancing patient education without causing fear 24:17 – Motor outcomes: strength, power and kinetic chain 24:43 – Assessment time and thoroughness at Pogo Physio 25:08 – Objective testing: dynamometers, balance and calf tests 25:38 – Balance test progressions as return-to-sport criteria 26:37 – Strength testing: inversion, eversion and calf raise endurance 27:07 – Power testing: triple hop, crossover hop and lateral hop tests 27:33 – Using objective markers to guide return-to-sport decisions 28:01 – Patient questionnaires: Cumberland Ankle Instability Tool (CAIT) and FAAM 28:57 – Coping vs non-coping athletes and objective scoring 29:25 – Moving into rehabilitation: individualised management 29:54 – Protection and appropriate early loading 30:20 – Moon boots and protecting specific structures 31:16 – ASO ankle braces for lower-grade sprains 31:45 – The strength, stability, mobility rehab framework 32:14 – Early loading phase: range of motion, balance and strength 32:43 – Addressing dorsiflexion loss 33:13 – The Torillin infographic on restriction sources 33:40 – Progressing balance and strength exercises 34:10 – Preventative efforts and integrating rehab into training 34:40 – Late-stage rehab and return-to-play criteria 35:39 – Bracing and taping to prevent recurrence 36:08 – Long-term consequences: osteoarthritis and ankle surgery risk 37:34 – Lewis's own experience with taping and bracing 38:02 – The biggest mistake athletes make in managing ankle sprains 39:29 – Lewis's top tip: get every ankle sprain assessed 40:27 – Where to reach Lewis Craig for questions 40:52 – Episode close and sponsor reminder 41:20 – Pogo Physio Telehealth Consultations and closing details THE TEAM: Join the The Physical Performance Show LEARNINGS membership through weekly podcasts here: https://www.patreon.com/TPPShow Our goal is to get you back to your Physical Best. Find out more about Telehealth Consultations and book online. Your Hosts:

Last week we named the problem: contempt is addictive, corrosive, and the #1 predictor of divorce. This week we take up the harder question—how do we actually walk away from it?We open with an honest look at whether it's possible to keep a largely contempt-free marriage while still participating in a culture that runs on contempt. The short answer: not in any deep or sustainable way. Contempt is a habit of mind, and habits don't stay neatly contained. What we practice outside the home eventually shapes the atmosphere inside it.From there we get practical. Drawing from Arthur Brooks' Love Your Enemies, John Gottman's research, and real marriage experience, we walk through six concrete steps for starving the contempt habit and practicing warm-heartedness—especially at home.In this episode we discuss:Why you can't fully separate “contempt out there” from “contempt at home”The quiet fears that grow in a spouse when contempt is part of the atmosphereTreating your marriage as the laboratory for changeThe 5-to-1 rule and why it mattersMaking a personal rule that contempt is never justifiedReal moral courage: standing up for people who believe differently than youStaying curious instead of assuming the worstReducing exposure to outrage cultureUsing moments of contempt as practice opportunitiesThis episode is about direction, not perfection. The goal is to begin walking away from contempt—on purpose, over time—starting with the person who knows you best.Book mentioned:Love Your Enemies by Arthur BrooksRelated episode:The Addiction of ContemptGet in TouchWebsite: MasterYourMarriage.usInstagram: https://www.instagram.com/masteryourmarriage

What if your migraine pattern is becoming more frequent before you even realize it?In this episode of Migraine Heroes Podcast, host Diane Ducarme explores eight subtle signs that episodic migraine may be moving toward a more chronic pattern—from mild headache days and longer recovery periods to increasing sensitivity and more frequent medication use.You'll discover:

Today's Sports Daily covers great numbers in the NFL on predicting game-by-game success, how one score win teams do the following season, and a crazy story about a cheating golfer getting kicked out of his own club.      Music written by Bill Conti & Allee Willis (Casablanca Records/Universal Music Group)  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Was, wenn der eigentliche Motor Deiner Bewegung nicht in Deinen Beinen sitzt, sondern in Deinem Rücken? In dieser Best-of-Folge nimmst Du das wenig bekannte Modell der Spinal Engine unter die Lupe, das die Wirbelsäule in den Mittelpunkt von Gehen, Laufen und fast jeder kraftvollen Bewegung stellt.Du erfährst, warum Rotation im Rumpf über Deine Effizienz entscheidet, wie ein Mensch ohne Beine in einem fast normalen Gangmuster laufen kann und was das ganz praktisch für Deinen Rücken, Deine Beweglichkeit und Dein Training bedeutet.Mark ordnet das Modell ehrlich ein, zeigt seine Stärken und seine Grenzen und gibt Dir ein paar einfache Übungen an die Hand, mit denen Du Deine Körpermitte geschmeidiger und stärker machst.Eine Folge, die Deinen Blick auf Bewegung verändert und Dir zeigt, wie Du Dich mit wenigen Impulsen spürbar jünger bewegst.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________

Send us Fan MailThere's one small habit — noticed decades ago by researchers watching married couples through a one-way mirror — that predicts, with startling accuracy, whether a relationship lasts or falls apart. It's not about how often you fight. It's not about compatibility. It's about a handful of tiny, easy-to-miss moments every single day — and whether you show up for them. This week, we're breaking down the research behind it, what it looks like in real life, and one simple habit you can start today.Quote of the week:"Good relationships keep us happier, healthier, and help us live longer." — Dr. Robert Waldinger, director of the Harvard Study of Adult DevelopmentCitations:·       Gottman, J. (research from The Love Lab, University of Washington); Gottman, J. & DeClaire, J., The Relationship Cure; Gottman, J., The Love Prescription·       Waldinger, R., The Good Life: Lessons from the World's Longest Scientific Study of Happiness; Harvard Study of Adult Development (adultdevelopmentstudy.org)Let's go, let's get it done.Get more information at: http://projectweightloss.org

What if you could see church growth coming before it actually arrives? In this episode of the Church Revitalization Podcast, Scott Ball and A.J. Mathieu walk through three leading indicators that can predict future church health and growth, rather than simply reviewing what has already happened. They explain the difference between lag measures (like attendance) and lead measures, and show how tracking the right numbers gives church leaders real leverage to make smarter decisions. Scott Ball and A.J. Mathieu are the co-hosts of the Church Revitalization Podcast, produced by the Malphurs Group, a church consulting and coaching organization. Scott serves as a Vice President at the Malphurs Group and works closely with churches navigating revitalization, while A.J. brings a background in church health strategy and practical leadership coaching. Together they make complex ministry concepts accessible and actionable for pastors and church leaders at every stage. [5:11] Lead vs. Lag Measures: The Odometer vs. Speedometer Analogy [7:55] Introduction to the Three Leading Indicators [9:08] Indicator 1: Connection Cards and First-Time Guest Engagement [15:16] Indicator 2: Moving People from Large Gatherings to Small Groups [17:46] Indicator 3: Volunteer Engagement as a Predictor of Church Health Free 7-Day Trial of the Healthy Churches Toolkit: https://healthychurchestoolkit.com Episode Article: https://malphursgroup.com/351 Facebook: https://facebook.com/malphursgroup Instagram: https://instagram.com/malphursgroup YouTube: https://youtube.com/themalphursgroup X: https://x.com/malphursgroup

Have you ever wondered how a child's ability to manage their emotions and impulses might shape their later mental health? And, what if one of the most important predictors isn't about how clever they are, but how well regulated they are on the inside? This episode of the Mind the Kids podcast features Lilja Jónsdóttir, a PhD student at the Department of Psychology at Uppsala University, Sweden, who will shortly take up a postdoctoral research position in child and adolescent psychiatry at Uppsala's Department of Medical Sciences. Hosted by Mark Tebbs, the conversation explores her paper, Examining Early Inhibitory Control and Emotional Regulation as Predictors of Childhood Internalizing and Externalizing Problems: A Longitudinal Study, co-authored with her supervisor Professor Karen Brocki, co-supervisors Dr. Matilda Frick and Dr. Andreas Frick of Stockholm University, and fellow PhD researcher Emma Heemann.The discussion unpacks the hierarchical development of self-regulation, examining how simpler skills such as inhibitory control — the ability to override an automatic impulse, illustrated through the classic marshmallow test — feed into more complex abilities like emotion regulation. Drawing on data from the long-running Effect Project, a longitudinal study following 94 typically developing children in Uppsala from infancy, Lilja explains how inhibitory control was measured at age four using the day-night Stroop task, emotion regulation was assessed at age six via validated parent-report measures, and internalizing and externalizing problems were captured at nine to ten years using the Strengths and Difficulties Questionnaire.Contrary to prior research and theoretical expectations, the study found no link between early inhibitory control and later emotion regulation or behavioural outcomes. Instead, emotion regulation at age six emerged as a robust, transdiagnostic predictor of both internalizing problems (such as worry and withdrawal) and externalizing problems (such as impulsivity and defiance) three to four years later — a finding that held even within a relatively advantaged community sample, strengthening the case for universal, early support.This conversation is essential listening for clinicians, educators, and parents interested in child development, self-regulation, and early intervention. Lilja discusses the importance of co-regulation between caregivers and children, promising directions for emotion-regulation-focused support, and why publishing null results — such as the absence of an inhibitory control effect here — matters for advancing the field.Read the JCPP Advances paper 'Examining early inhibitory control and emotion regulation as predictors of childhood internalizing and externalizing problems: A longitudinal study'Lilja K. Jónsdóttir, Matilda A. Frick, Andreas Frick, Emma J. Heeman, Karin C. BrockiFirst published: 07 January 2026 https://doi.org/10.1002/jcv2.70093Get a free CPD/CME certificate for listening to this podcast by registering for a FREE ACAMH Learn account at https://bit.ly/4fF4BBWVisit https://www.acamh.orgFacebook and LinkedIn search / ACAMHInstagram https://www.instagram.com/assoc.camhBluesky https://bsky.app/profile/acamh.bsky.socialX https://x.com/acamh

Aging after 50 doesn't have to be an uphill battle. Discover the single greatest marker of aging and longevity, how to work with your body to age gracefully, evidence-based longevity tips, and the critical role of mitochondrial health.0:00 Aging gracefully after 500:38 VO2 max and longevity1:26 Metabolic health explained2:45 Aging biomarkers after 503:41 The truth about cholesterol and longevity6:18 Genetics and aging6:59 No energy for exercise 7:35 The top anti-aging supplements8:28 Longevity tips Download Dr. Berg's Free Daily Health Routine: https://drbrg.co/4tO9nV9 

Dr. Eric explains how grip strength is a marker not only of longevity but also overall health and performance. Listen up!www.drericprimex.com

ArticlesComparison of Functional Outcomes and Safety of Acute Carotid Stent Placement versus Thrombectomy Alone in the Treatment of Patients with Tandem Occlusions in Acute Ischemic Stroke (Read)Portal Vein Stent Placement in a Pancreatic Cancer Cohort: Outcomes and Predictors of Portal Stent Occlusion (Read)Stereotactic Percutaneous Thermal Ablation of Primary and Metastatic LiverTumors: A Prospective Registry-Based Study (Read)HostMarie Hamel, the Warren Alpert Medical School of Brown UniversityAudio editorAndrew Sasser, University of Miami Leonard M. Miller School of MedicineAbstract readersDonald Chow, Saint Louis University School of MedicineEvan Massa, Philadelphia College of Osteopathic MedicineSara Sadok, University of Illinois College of Medicine - ChicagoSupport the show

In this episode of Durable Value, Joe and Ryan discuss how most institutional investors skip secondary and tertiary real estate markets; but what if the "perceived risk" is actually lower than primary markets? Here we break down the data behind secondary market investing: why volatility is lower, why liquidity is stronger than you'd expect, and why institutional capital clustering in gateway cities may be the real risk. We also share a real-world example of selling an office building in 2026, and generating a 16% gross IRR, to prove the thesis.0:00 – Introduction: Secondary Markets & The Risk Mispricing Thesis1:28 – The 20-Year Data Study (GFC, COVID, Rate Hikes)4:36 – Institutional Capital as a Predictor of Oversupply5:07 – Why Capital Clusters in Primary Markets (Career Risk & Benchmarks)7:01 – The Liquidity Myth: Where Transactions Actually Happen8:04 – Are Secondary Markets Becoming Institutionalized?11:34 – How to Execute: Macro Trends + Local Boots on the Ground

This week, James Weaver and Alex Vigderman dive under the hood of our College Football Playoff Predictor Model. James explains what drives its predictions from a modeling perspective and the nuances of trying to predict what humans are thinking when placing teams into the playoffs. The duo also discusses future enhancements and how the model will be utilized moving forward.Off The Charts features a blend of statistical insights, tactical analysis, and personal opinions, aimed at providing listeners with a comprehensive understanding of the week's key matchups and the intricacies of the sport. You can follow our content on Twitter at @Football_SIS, on Bluesky at @sportsinfosis.bsky.social and at sportsinfosolutions.com.

The boys are all back in the hotseat to look back on our 2-1 win over Queen's Park on Saturday before turning our attention to our visit to Palmerston Park on Wednesday evening and we bring you our patented 2026-27 Season Predictor!   Become a paid subscriber over at abzfootballpodcast.com   Follow us on our social media channels:-   Twitter - @AbzPodcast Facebook - @ABZFootballPodcast Instagram - @abzfootballpodcast

Featuring a slide presentation and related discussion from Prof Dr Sibylle Loibl, including the following topics: ·      Overview of the changing landscape of treatment for patients with HER2-positive metastatic breast cancer (mBC) (0:00) ·      Results from the CLEOPATRA, PATINA and HER2CLIMB-05 trials of first-line treatment and maintenance approaches for HER2-positive mBC (5:26) ·      Efficacy and safety findings from the Phase III DESTINY-Breast09 trial comparing trastuzumab deruxtecan with or without pertuzumab to taxane/trastuzumab/pertuzumab as first-line therapy for HER2-positive mBC (14:56) ·      Predictors of long-term benefit from first-line treatment with HER2-targeted agents; contribution of pertuzumab to the efficacy of first-line HER2-targeted combination regimens (22:57) ·      Control of brain metastases and CNS disease with first-line HER2-targeted regimens (26:31) CME information and select publications

On Episode 66 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the July 2026 issue of Stroke: "Liraglutide and Recurrent Stroke by Baseline Insulin Resistance: A Post Hoc Analysis of the LAMP Trial" and "Predictors of Hematoma Expansion and Response to Andexanet in Patients With Intracerebral Hemorrhage: Secondary Analyses of the ANNEXA-I Randomized Clinical Trial." She also interviews Dr. Diana Aguiar de Sousa about the EXCOA-CVT trial, presented recently at the European Stroke Organisation Conference. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260715.563317

What happens when frustration quietly turns into contempt—and what does that mean for the future of your relationship? In this conversation, we sit down with relationship therapist and author Zach Brittle to unpack one of the most destructive dynamics couples experience and why it's often misunderstood.Together, we explore where contempt comes from, how unrealistic expectations and unspoken needs fuel disconnection, and what it really takes to rebuild trust and intimacy. If you've ever wondered whether your relationship is stuck in a painful cycle—or how to shift it—this episode is full of practical insights that will challenge the way you think about connection.Episode Highlights[0:03] – Welcoming Zach Brittle and introducing why contempt is one of the biggest threats to healthy relationships.[1:20] – The Gottman Method, the Four Horsemen, and why contempt stands apart from the rest.[5:25] – How contempt develops over time and why it's far more than simply feeling annoyed with your partner.[7:50] – Expectations, comparison, and the hidden ways resentment begins to grow.[10:37] – Solvable versus perpetual relationship problems—and why acceptance matters.[13:19] – Losing positive sentiment and how couples begin viewing everything through a negative lens.[15:50] – Recognizing the warning signs before contempt becomes the default dynamic.[18:40] – The importance of asking clearly for what you need instead of expecting your partner to read your mind.[20:41] – When your needs aren't being met: accepting reality, setting boundaries, and making difficult relationship decisions.[22:08] – Why trying to "win" or change your partner often creates even more distance and frustration.[24:27] – A memorable analogy using sexual communication to explain why direct feedback strengthens connection.[26:13] – What being a responsive partner really looks like and why assumptions get couples into trouble.[28:36] – The "pasta and mailbox" examples: how neutral everyday actions can be interpreted through either appreciation or resentment.[30:02] – Negative sentiment override, confirmation bias, and why we often assume the worst of the people we love.[32:00] – Challenging the stories we tell ourselves and taking responsibility for how we show up in conflict.[35:28] – Practical ways to intentionally cultivate appreciation and prevent resentment from becoming contempt.[36:52] – Zach shares his latest book, his Substack, final relationship wisdom, and where listeners can connect with him.Links & ResourcesMarriage Therapy Radio Podcast: https://podcasts.apple.com/us/podcast/marriage-therapy-radio/id1295458667Zach Brittle's Books: https://zachbrittle.com/writing/Instagram: https://www.instagram.com/marriagetherapyradio/Facebook: https://www.facebook.com/marriagetherapyradio/TikTok: https://www.tiktok.com/@marriagetherapyradioIf today's discussion resonated with you or sparked curiosity, please rate, follow, and share "Insights from the Couch" with others. Your support helps us reach more people and continue providing valuable insights. Here's to finding our purposes and living a life full of meaning and joy. Stay tuned for more!Ever stayed quiet to keep the peace and felt yourself disappear? The Cost of Quiet is for anyone who avoids conflict and pays the price. Reclaim your voice, strengthen your relationships, and experience real peace. Order your copy and join the movement: https://www.colettejanefehr.com/new-book

What if the sounds everyone else ignores, the dishwasher, traffic, voices, music, or even someone chewing, feel painfully loud to your migraine brain?In this episode of Migraine Heroes Podcast, host Diane Ducarme explores why sound sensitivity is not being dramatic, fragile, or difficult. It may be a sign that your nervous system is already overwhelmed, sensitized, or moving toward a migraine attack.We look at sound sensitivity through both Western neuroscience and Eastern medicine, helping you understand why everyday noise can feel like too much — and what your body may be trying to tell you.You'll discover:

Helping a young person choose a career starts with asking better questions, not having every answer.In this solo episode, Lisa Marker-Robbins challenges the common ways families approach career planning and introduces a fresh perspective that expands possibilities for teens, college students, and young adults.Rather than focusing on majors, prestige, or job market predictions, Lisa explains why looking at the type of work a person is wired to enjoy creates stronger long-term career confidence. She also shares practical ways parents can shift from feeling responsible for finding the right answer to becoming a trusted thinking partner as their child explores future opportunities.In this episode, you'll discover:A broader way to think about career planning that goes beyond majors and job titlesWhy preparing for life after graduation requires a different mindset than preparing for graduationHow self-awareness can uncover career paths that fit a person's natural strengthsThe role parents can play in encouraging exploration instead of rushing decisionsKey Takeaways: Parents and high schools often focus on passions, academic strengths, job outlook, or prestige, but those factors alone create an incomplete picture when helping a young person choose a career.Organizing career exploration around the U.S. Department of Labor's job family framework helps students identify the type of work that fits their natural wiring instead of committing too early to a specific major or profession.Career clusters can help students choose classes and educational pathways, while job families encourage a longer-term view of career fit and adaptability as occupations continue to evolve.Parents can reduce pressure by asking thoughtful questions, encouraging exploration before commitment, and helping their child recognize recurring patterns in their interests and strengths instead of trying to provide all the answers. “Families often think that what they really want is a major... What you really want is a confident path to the future.” – Lisa Marker-RobbinsEpisode References:#221 The #1 Predictor of Your Child's Career Success (It's Not What You Think) https://flourishcoachingco.com/221Job Families Sample with Birkman Report: https://flourishcoachingco.com/jobsLearn more about Launch Career Clarity at FlourishCoachingCo.com/courseGet Lisa's Free on-demand video: THE CAREER IDENTIFICATION COMPASS: How To Be Certain Your 15 To 25 Year Old is On The Right Path to Launch With Confidence–Not Confusion: flourishcoachingco.com/video Connect with Lisa:Website: https://www.flourishcoachingco.com/YouTube: https://www.youtube.com/@flourishcoachingcoFacebook: https://www.facebook.com/flourishcoachingco/ Instagram: https://www.instagram.com/flourishcoachingco/LinkedIn: https://www.linkedin.com/company/flourish-coaching-co

Could high blood pressure be quietly adding pressure to your migraine brain?In this episode of Migraine Heroes Podcast, host Diane Ducarme explores how blood pressure, circulation, and nervous system stress may play a hidden role in migraine attacks. You'll learn why migraines may not be just a “head problem,” but a signal that your whole body needs deeper support.You'll discover:

El factor que mejor predice la felicidad es la calidad de nuestras relaciones. En este episodio, profundizamos en los miedos que nos mantienen aislados y aprendemos formas de construir relaciones desde el desapego. Aprenderás:-qué son el aislamiento social y la soledad-los peligros del aislamiento social-sobre nuestra necesidad fundamental de pertenencia-a construir conexiones basadas en la autenticidadescucha el episodio aquí: https://youtu.be/Qvz0m1HOtFove el episodio de la comunicación asertiva aquí: https://youtu.be/cutv14-O2ZQ?si=twgHHSEs2vm1ds8b

Content Warning: Graphic descriptions of Child Sexual Abuse Material (CSAM) file names.In this episode of 'One in Ten,' host Teresa Huizar interviews Dr. Ted Cross of the University of Illinois Urbana-Champaign about how child sexual abuse material (CSAM) reflects and perpetuates ongoing abuse. Cross explains why CSAM replaces “child pornography,” emphasizing that its creation requires contact abuse and its dissemination retraumatizes victims for years. To study CSAM without viewing traumatic content or violating privacy, his team partnered with the Child Rescue Coalition and analyzed nearly 3,000 highly descriptive filenames as a proxy for content. Findings included a predominance of videos, victims across all ages (including infants), a large share depicting ages 5–12, and common incest/familial cases (over 40%) that tended to involve more severe abuse. Filenames referencing children of color were more likely to include penetration. Cross urges CACs and MDTs to investigate possible online abuse in contact cases, secure devices, and strengthen partnerships with state ICAC task forces.  Time Stamps Time Topic 00:00 Episode Introduction 01:26 Meet Dr Ted Cross 02:48 What CSAM Means 04:10 Who Produces CSAM 05:30 Ethical Study Design 06:50 Filenames As Proxy Data 10:08 Victim Demographics 11:50 Incest And Severity 12:52 Penetration And Harm 14:27 Practice Implications 16:19 Trauma And Disclosure 18:25 Policy And Prevention 19:34 Future Research Directions 22:25 Final Takeaways 23:52 Closing And Resources  ResourcesChild Rescue CoalitionCharacteristics of Child Sexual Abuse Material in Peer-to-Peer Networks and Predictors of its Severity: Insights From Filenames - Theodore P. Cross, Elizabeth M. Cross, Camille Cooper, Daphne Pellegrino, Glen Pounder, Stefan Turkheimer, Simon Bailey, 2025Support the showDid you like this episode? Please leave us a review on Apple Podcasts.

The guys discuss the ESPN's ranking of the Vikings roster. Marney gives her take on Lebron to the Wolves. Predictors Part II makes its Power Trip debutSee omnystudio.com/listener for privacy information.

The guys discuss the ESPN's ranking of the Vikings roster. Marney gives her take on Lebron to the Wolves. Predictors Part II makes its Power Trip debut

Time has a way of speeding up, especially when major decisions about school, careers, and independence are on the horizon.In this solo episode, Lisa Marker-Robbins encourages parents to pause for a mid-year career clarity check, helping families assess where teens, college students, and young adults stand before the next milestone arrives.She walks through four key stages families face when preparing to launch their young person into adult independence while explaining why direction requires intention rather than waiting for time to solve uncertainty. Along the way, Lisa shares practical questions and conversation strategies to help families build confidence, foster greater ownership, and prepare for the second half of the year.In this episode, you'll discover:How career clarity changes across the different stages of a young person's developmentThe common patterns that leave families feeling behind as major milestones approachWhy intentional planning matters more than waiting for maturity or time to create directionWays parents can encourage greater ownership while preparing students for increasing independenceKey Takeaways: (04:14) Milestone #1: High School Years — Students need more than a plan after graduation. They need to understand why they're choosing a particular path and ensure their decisions align with long-term career goals.(09:00) Milestone #2: Around Age 20 — By this stage, families should look for evidence of intentional progress rather than assuming maturity alone will create direction or career momentum.(13:52) Milestone #3: The First Career Search — Landing a career requires more than credentials. Young adults need the self-awareness and communication skills to explain the value they bring to an employer.(19:09) Milestone #4: The Launch Line — Parents can best support independence by leading conversations with empathy and curiosity while encouraging greater ownership instead of stepping in to solve every problem. “Lead the discussion with questions and curiosity, not with directives or orders.” – Lisa Marker-RobbinsEpisode References:Learn more about Launch Career Clarity at FlourishCoachingCo.com/course#169 The Hidden Impact of College Major Selection on Admissions with Rick Clark: https://flourishcoachingco.com/169#212 How to Choose a College That Delivers Career ROI, with Jeff Selingo: https://flourishcoachingco.com/212#221 The #1 Predictor of Your Child's Career Success (It's Not What You Think): https://flourishcoachingco.com/221Get Lisa's Free on-demand video: THE CAREER IDENTIFICATION COMPASS: How To Be Certain Your 15 To 25 Year Old is On The Right Path to Launch With Confidence–Not Confusion: flourishcoachingco.com/video Connect with Lisa:Website: https://www.flourishcoachingco.com/YouTube: https://www.youtube.com/@flourishcoachingcoFacebook: https://www.facebook.com/flourishcoachingco/ Instagram: https://www.instagram.com/flourishcoachingco/LinkedIn: https://www.linkedin.com/company/flourish-coaching-co

Jann, Caitlin & Sarah catch up about Caitlin's search for a new home, summer activities in Iceland, and the excitement surrounding the World Cup. Caitlin fills us in about the ranch dressing craze among European soccer fans, and the commercialization of the fan detested hydration breaks.  Jann also invites app developer Travis Weniger to discuss his app, Memento Mori. It predicts life expectancy based on various health metrics while blending the philosophies of stoicism and longevity. The conversation delves into the importance of recognizing life's finiteness. Travis shares insights on how discussions about death can lead to a more fulfilling life, and the importance of balancing enjoyment with health-conscious choices. The conversation explores mortality, and the importance of living meaningfully. More About Travis Weninger: Travis Weninger is an independent product designer, developer, and writer based in Toronto. His work explores the intersection of technology, philosophy, and intentional living. After spending nearly a decade working in the tech industry, he left the corporate world to pursue his own path and founded socialdotgood, an independent software company focused on building thoughtful consumer products. Through socialdotgood, Travis has launched six apps, with Memento Mori being his most ambitious project to date. Inspired by Stoic philosophy and the ancient practice of reflecting on mortality, the app is a meditation on one's mortality paired with contemporary research on longevity. Resources & Links: YearsLeft.io – Travis Weniger's mortality prediction app https://www.blogto.com/tech/2026/02/toronto-app-raising-eyebrows/ https://www.blogto.com/tech/2026/04/toronto-app-predict-when-die/ #ASKJANN - want some life advice from Jann? Send in a story with a DM or on our website. Leave us a voicenote! ⁠www.jannardenpod.com/voicemail/⁠⁠ Get access to bonus content and more on Patreon: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.patreon.com/JannArdenPod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Connect with us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.jannardenpod.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.instagram.com/jannardenpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.facebook.com/jannardenpod Chapters: (00:00) Introduction and Catch-Up (03:04) Moving Challenges and Life Updates (06:00) Summer in Iceland and Family Activities (08:51) World Cup Excitement and Cultural Discoveries (12:02) Hydration Breaks and Commercialization in Sports (14:58) Social Dynamics During the World Cup (17:49) Legacy and the Concept of Time (22:02) Introducing Travis and the Memento Mori App (25:50) The Intimacy Tracking App (28:15) Philosophical Insights on Life and Death (32:03) Mitigating factors that impact longevity (36:17) Death app demo in Patreon Learn more about your ad choices. Visit megaphone.fm/adchoices

Relapsing is such a common experience for people early in recovery. This episode is going to be really important for those who are exploring all the nuances of how people find recovery and the predictors of long-term recovery.  Before we jump in, if you haven't yet, please consider supporting the podcast by joining the YouTube members only content for just $1.99 per month. It's ad free content and by showing your support, I can keep creating free content for you. The podcast costs about $500 per month so every little bit helps. Thank you so much! Today I sit down with Dr. Ross Ellenhorn, a sociologist and founder of Ellenhorn, one of the most robust community integration programs in the United States. For over 20 years, Dr. Ellenhorn has been running what he calls a "hospital without walls" - a program that meets people where they are, literally going to school with clients, accompanying them to jobs, and helping them rebuild their lives inside their communities rather than removing them from those communities to treat them.  In this episode, you'll learn: • What "fear of hope" is and how it quietly blocks people from moving forward • Why denial and resistance are more about your environment than your psychology • How self-efficacy and pride are the real building blocks of lasting recovery and • The difference between hope and faith - and why both matter for recovery So without further delay, please enjoy this episode with Dr Ellenhorn.   Guest Website: https://ellenhorn.com 

Humility is one of the most quietly powerful practices for positive psychology and mental health. It's also one of the most misunderstood. Here's the heart of it: humility is not a weakness. It's not about making yourself small or performing modesty for social approval. It's an accurate, grounded sense of self, what Dr. Daryl Van Tongeren calls "right-sizing." You own your strengths and weaknesses. And you hold your worth steady through all of it. We explored four types of humility this month: relational, intellectual, cultural, and existential. And we worked through three core ingredients to build humility up: Know Yourself. This is where self-compassion becomes essential. Self-knowledge without self-compassion tends to slide into rumination — that harsh, looping self-focus that keeps us stuck. Dr. Kristin Neff's research reminds us that genuine self-reflection requires feeling safe enough to look clearly, without bracing for an attack. When self-compassion is in place, honest self-awareness becomes possible. So does recognizing things like the better-than-average effect, which is our tendency to unconsciously and inaccurately position ourselves as a little more right, and others a little more wrong. Humility gently corrects that drift. Check Yourself. This is ego territory. When we feel threatened, the ego rises up. We deflect, deny, shut down, intellectualize. It's a very human, very normal response. But it doesn't have to run the show. One of the most practical tools from this series: when you feel defensive, pause. Breathe. Then ask yourself, "What would I think if I weren't feeling defensive?" That question can create some space for the ego to stand down and lets emotional regulation take over instead of reactivity. Go Beyond Yourself. This is where the magic of humility really shows itself as we build a genuine curiosity about other people and life's bigger questions. The self-forgetfulness that C.S. Lewis describes as essential to humility puts it all into action. When we're not so consumed by ourselves, the world opens up. And that's where connection, meaning, and joy actually show up in more noticeable, lasting ways. If you've worked through this series and feel less certain than when you started, that's not a problem. That's the practice of humility in action. Sitting with uncertainty, tolerating what's unresolved, resisting the cultural pressure toward easy answers and performed confidence is peak courage. It's often uncomfortable and it's always worth it. If this work has stirred something that feels bigger than you want to carry alone, please reach out to a therapist, a trusted friend, or a support community. Seeking support isn't weakness. It's an act of humility and one of the most courageous things you can do. And for Joy Lab Program members: your Episode Experiment includes a guided meditation and journal prompts to help you harvest and integrate the work you've done this month.  We close with Rilke (we know, we close with Rilke a lot!): "Be patient toward all that is unsolved in your heart and try to love the questions themselves." Keep tending to your humility. It grows good things.   About: The Joy Lab Podcast is an Ambie-nominated podcast that blends science and soul to help you cope better with stress, anxiety, and depression. It's hosted by integrative psychiatrist Dr. Henry Emmons and holistic mental health researcher Dr. Aimee Prasek. The podcast is best paired with the Joy Lab Program (get your 7-day free trial!). Bonus: spread some joy and keep this podcast ad-free by donating (Joy Lab is powered by the nonprofit Pathways North and your donations are tax-deductible).       Sources and Notes for our Element of Humility: Joy Lab Program: Take the next leap in your wellbeing journey with step-by-step practices to help you build and maintain the elements of joy in your life. Start your 7-day free trial now. Episodes in this Humility series: Humility Can Be Stressful... But Worth it for Mental Health [ep. 268] Know Yourself: The Humility Practice That Quiets Rumination and Builds Emotional Resilience [ep. 269] Check Yourself: Ego Threat, Stress Relief, & Needing to Prove Yourself [270] Book: Humble by Daryl Van Tongeren, PhD Tara Brach's website Find more about Neff's work on Self-compassion at Self-Compassion.org More on C.S. Lewis from the C.S. Lewis Foundation.  Hagá & Olson. 'If I only had a little humility, I would be perfect': Children's and adults' perceptions of intellectually arrogant, humble, and diffident people. Access here. Nielsen & Marrone. Humility: Our current understanding of the construct and its role in organizations. Access here. Porter et al. Predictors and consequences of intellectual humility. Access here. Van Tongeren et al. Humility. Access here.  Weidman et al. The psychological structure of humility. Access here. Wright et al. The psychological significance of humility. Access here. Wendell Berry's book Standing by Words   Common Questions: Q: How do I stop being so hard on myself without losing self-awareness? A: Self-compassion and self-knowledge are partners. As researcher Dr. Kristin Neff puts it, "You can look clearly at yourself when you're not afraid of what you'll find." Self-compassion creates the psychological safety for honest, accurate self-appraisal, replacing harsh rumination with compassionate self-reflection. Humility is the result: an accurate, grounded sense of self that's neither inflated nor deflated. Q: Why does being humble feel so uncomfortable and countercultural? A: Because in many ways, it is. We live in a world that often rewards certainty, self-promotion, and being right, even when those things don't actually nourish us. Building humility means opening up to uncertainty and the unknown, which takes real courage. The good news is that discomfort is also building something called uncertainty-tolerance, a form of emotional resilience that reaches across every area of your life in really nourishing ways.   Key moments: [00:00] Welcome & orientation — Aimee frames the three-part humility arc (Know Yourself → Check Yourself → Go Beyond Yourself) [01:30] Henry's realization: humility, like every Joy Lab Element, is ultimately about learning to love well and connect more deeply [03:00] Why humility is the antidote to loneliness — the difference between being surrounded by people and being genuinely seen; how isolation is really a form of alienation [05:00] What it feels like to be with a truly humble person — and why humility makes us safer, more trustworthy, and more magnetic in relationships and communities [06:30] The traffic circle of defensiveness — Aimee on why the risk of being burned by someone is still better than a lifetime of self-protective looping [07:30] Epistemic humility explained — the idea that your understanding of reality is always partial, always filtered, always a vantage point. And so is everyone else's. (Plus: a pronunciation debate.) [08:45] Why disagreement doesn't mean someone is wrong, and how truth is larger than any one person's grasp of it [10:30] William James on the deepest craving in human nature: to be appreciated and seen [11:00] Two practical strategies for going beyond yourself: (1) deep, active listening as a humility practice — not formulating your response, but truly receiving another person; (2) seeing the innocence of others [12:30] Thich Nhat Hanh: "Listen until they empty their hearts." Henry shares this as a guide for showing up and listening [13:30] Seeing the innocence in others — Henry's 30+ years of clinical wisdom distilled: most people are doing the best they can with what they have, right now. How holding that awareness softens judgment without eliminating boundaries [15:30] Aimee reflects: "That's the wisdom I'd want somebody to hold when they see me messing up." [16:00] Experiment preview for Joy Lab Program members + closing Rumi quote: "You are not a drop in the ocean, you are the entire ocean in a drop."    Like and follow Joy Lab on Socials:  Instagram Linkedin Facebook YouTube   Please remember that this content is for informational and educational purposes only. It is not intended to provide medical advice and is not a replacement for advice and treatment from a medical professional. Please consult your doctor or other qualified health professional before beginning any diet change, supplement, or lifestyle program. Please see our terms for more information. If you or someone you know is struggling or in crisis, help is available. Call the NAMI HelpLine: 1-800-950-6264 available Monday through Friday, 10 a.m. – 10 p.m., ET. OR text "HelpLine" to 62640 or email NAMI at helpline@nami.org. Visit NAMI for more. You can also call or text SAMHSA at 988 or chat 988lifeline.org.

In this episode of PICU Doc on Call, hosts Dr. Monica Gray and Dr. Pradip Kamat explore procedural sedation in the pediatric ICU. They cover sedation levels, pre-screening, risk stratification using ASA classifications, and medication selection tailored to each patient's hemodynamic and respiratory status. Through real-world case discussions involving respiratory failure, septic shock, and acute neurological decline, they highlight the importance of end-tidal CO2 monitoring and early adverse event recognition. Key takeaways include avoiding the term "conscious sedation," preparing rescue plans, and prioritizing patient safety through careful assessment and monitoring.Show Highlights:Definitions and levels of sedation (minimal, moderate, deep sedation, and general anesthesia)Importance of terminology in procedural sedationMonitoring sedation levels using scales like the Richmond Agitation-Sedation Scale (RASS)Pre-screening and risk stratification considerations for pediatric patientsASA physical status classification system for assessing patient riskUnique challenges of procedural sedation in critically ill childrenAdverse events associated with pediatric procedural sedation, particularly respiratory complicationsManagement strategies for specific cases requiring sedation (e.g., respiratory failure, septic shock)Importance of end-tidal CO2 monitoring during sedationKey takeaways for safe sedation practices in the pediatric ICU settingReferences: Nir Atlas; Rahul C. Damania; Pradip P. Kamat In Fuhrman & Zimmerman - Textbook of Pediatric Critical Care Chapter 135, 1624-1628Statement on Continuum of Depth of Sedation: Definition of General Anesthesia and Levels of Sedation/Analgesia by Committee on Quality Management and Departmental Administration. Last Amended: October 23, 2024.Coté CJ, Wilson S; AMERICAN ACADEMY OF PEDIATRICS; AMERICAN ACADEMY OF PEDIATRIC DENTISTRY. Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures. Pediatrics. 2019 Jun;143(6):e20191000. doi: 10.1542/peds.2019-1000. PMID: 31138666.xKrauss B, Green SM. Procedural sedation and analgesia in children. Lancet. 2006 Mar 4;367(9512):766-80. doi: 10.1016/S0140-6736(06)68230-5. PMID: 16517277.Sharif S, Kang J, Sadeghirad B, Rizvi F, Forestell B, Greer A, Hewitt M, Fernando SM, Mehta S, Eltorki M, Siemieniuk R, Duffett M, Bhatt M, Burry L, Perry JJ, Petrosoniak A, Pandharipande P, Welsford M, Rochwerg B. Pharmacological agents for procedural sedation and analgesia in the emergency department and intensive care unit: a systematic review and network meta-analysis of randomised trials. Br J Anaesth. 2024 Mar;132(3):491-506. doi: 10.1016/j.bja.2023.11.050. Epub 2024 Jan 6. PMID: 38185564.Smith, Heidi A. B. MD, MSCI (Chair)1,2; Besunder, James B. DO, FCCM3,4; Betters, Kristina A. MD1; Johnson, Peter N. PharmD, BCPS, BCPPS, FCCM, FPPA, FASHP5,6; Srinivasan, Vijay MBBS, MD, FCCM7,8; Stormorken, Anne MD9,10; Farrington, Elizabeth PharmD, FCCM11; Golianu, Brenda MD12,13; Godshall, Aaron J. MD14; Acinelli, Larkin CPNP-AC, ACHPN15; Almgren, Christina CPNP16; Bailey, Christine H. MD17; Boyd, Jenny M. MD18,19; Cisco, Michael J. MD20; Damian, Mihaela MD, MPH21,22; deAlmeida, Mary L. MD23,24; Fehr, James MD13,25; Fenton, Kimberly E. MD, FCCM14; Gilliland, Frances DNP, CPNP-AC/PC26,27; Grant, Mary Jo C. CPNP-AC, PhD, FAAN28; Howell, Joy MD29; Ruggles, Cassandra A. PharmD, BCCCP, BCPPS30; Simone, Shari DNP31,32; Su, Felice MD21,22; Sullivan, Janice E. MD33,34; Tegtmeyer, Ken MD, FAAP, FCCM35,36; Traube, Chani MD, FCCM29; Williams, Stacey CPNP-AC37; Berkenbosch, John W. MD, FAAP, FCCM (Chair)33,34. 2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility. Pediatric Critical Care Medicine 23(2):p e74-e110, February 2022. | DOI: 10.1097/PCC.0000000000002873Benzoni T, Agarwal A, Cascella M. Procedural Sedation. [Updated 2025 Mar 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK551685/Kerson AG, DeMaria R, Mauer E, Joyce C, Gerber LM, Greenwald BM, Silver G, Traube C. Validity of the Richmond Agitation-Sedation Scale (RASS) in critically ill children. J Intensive Care. 2016 Oct 26;4:65. doi: 10.1186/s40560-016-0189-5. PMID: 27800163; PMCID: PMC5080705.Tel-Dan SF, Shavit D, Nates R, Samuel N, Shavit I. Emergency Physician-Administered Sedation for Thoracostomy in Children With Pleuropneumonia. Pediatr Emerg Care. 2021 Dec 1;37(12):e1209-e1212. doi: 10.1097/PEC.0000000000001975. PMID: 31929389.Cosgrove P, Krauss BS, Cravero JP, Fleegler EW. Predictors of Laryngospasm During 276,832 Episodes of Pediatric Procedural Sedation. Ann Emerg Med. 2022 Dec;80(6):485-496. doi: 10.1016/j.annemergmed.2022.05.002. Epub 2022 Jun 23. PMID: 35752522.Cravero JP, Blike GT, Beach M, Gallagher SM, Hertzog JH, Havidich JE, Gelman B; Pediatric Sedation Research Consortium. Incidence and nature of adverse events during pediatric sedation/anesthesia for procedures outside the operating room: report from the Pediatric Sedation Research Consortium. Pediatrics. 2006 Sep;118(3):1087-96. doi: 10.1542/peds.2006-0313. PMID: 16951002.

What if one of the most important health crises affecting men today wasn't being caused by aging, but by the environment we live in? In this eye-opening solo episode, Darin Olien investigates the alarming decline in testosterone levels, fertility, and reproductive health among men worldwide. Drawing on decades of research, epidemiological studies, environmental science, endocrinology, and public health data, Darin examines the growing evidence connecting endocrine-disrupting chemicals, microplastics, sleep deprivation, chronic stress, poor lifestyle habits, and environmental toxins to declining testosterone levels across generations. From BPA, phthalates, atrazine, PFAS, and microplastics to sleep quality, circadian rhythms, cholesterol metabolism, cortisol regulation, and natural testosterone-supporting strategies, this episode explores what may be one of the most underreported public health issues of our time—and what men can do to take control of their health today.     What You'll Learn Why testosterone levels have been declining for decades The startling research on global sperm count decline How endocrine-disrupting chemicals interfere with hormone production Why BPA and phthalates may disrupt testosterone synthesis The role of atrazine, PFAS, and environmental toxins How chronic stress diverts resources away from testosterone production Why sleep may be the most important testosterone intervention The connection between cholesterol and hormone production How microplastics are being found throughout the human body The surprising relationship between statins and testosterone levels Natural lifestyle strategies that support healthy hormone production Practical steps to reduce environmental exposure and improve health     Chapters 00:00:00 – Welcome to SuperLife 00:00:33 – Sponsor: Fatty15 and cellular health 00:04:17 – The testosterone collapse explained 00:04:51 – Testosterone levels have been declining for decades 00:06:03 – Global sperm count decline and accelerating trends 00:07:02 – Why treating symptoms misses the root cause 00:07:27 – The hidden public health crisis 00:08:03 – Why low testosterone isn't just about aging 00:09:12 – Why hormone health affects longevity 00:09:53 – Low testosterone and increased mortality risk 00:10:35 – Testosterone's role in metabolism and cardiovascular health 00:11:27 – Endocrine-disrupting chemicals and hormone disruption 00:12:44 – BPA and its effects on testosterone production 00:13:59 – Phthalates and their impact on hormone pathways 00:16:00 – Glyphosate, atrazine, and pesticide exposure 00:17:07 – PFAS and reproductive health concerns 00:17:55 – Environmental toxins and population-wide effects 00:18:11 – Sponsor: Shakeology 00:20:02 – Cholesterol and hormone production 00:20:53 – Chronic stress and cortisol dominance 00:21:45 – Actionable solutions begin 00:21:56 – Why sleep is essential for testosterone production 00:23:07 – How sleep deprivation rapidly lowers testosterone 00:23:21 – Light pollution and circadian disruption 00:23:41 – Foods and nutrients needed for hormone health 00:24:23 – Microplastics and testicular tissue 00:24:53 – Statins and unintended hormonal consequences 00:25:39 – A practical testosterone sovereignty protocol 00:25:48 – Water filtration and reducing toxic exposure 00:26:13 – Eliminating plastics and fragrance chemicals 00:26:35 – Why organic food matters 00:26:45 – Sunlight and vitamin D 00:27:05 – Magnesium, omega-3s, and iodine 00:27:26 – Pine pollen and natural androgen support 00:28:01 – Tongkat Ali and ashwagandha 00:28:48 – Strength training and lifestyle interventions 00:29:10 – Habits that naturally support testosterone 00:29:27 – Darin's approach to healthy aging 00:29:37 – Plants, herbs, and common sense 00:29:51 – Reclaiming your health and sovereignty 00:30:00 – Final thoughts and closing message     Thank You to Our Sponsors Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Shakeology: Get 15% off with code DARINO1BODI at Shakeology.com.     Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien     Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness     Key Takeaway "The testosterone crisis may be about far more than aging. It may be a reflection of the modern environment itself—one increasingly saturated with endocrine-disrupting chemicals, chronic stress, poor sleep, circadian disruption, and toxic exposures. While many of these forces feel outside our control, the encouraging reality is that many of the most powerful interventions remain accessible: improving sleep, reducing toxic load, eating whole foods, getting sunlight, managing stress, exercising regularly, and reclaiming responsibility for our health. The goal isn't fear. The goal is awareness—and action."     Bibliography/Sources: The Decline — Primary Research Levine, H., Jørgensen, N., Martino-Andrade, A., et al. (2022). Temporal trends in sperm count: A systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Human Reproduction Update, 29(2), 157–176. https://doi.org/10.1093/humupd/dmac035 Lokeshwar, S. D., Patel, P., Fantus, R. J., et al. (2021). Decline in testosterone levels in men aged 15–40: Results from the National Health and Nutrition Examination Survey (NHANES), 1999–2016. World Journal of Urology, 39(2), 447–452. https://doi.org/10.1007/s00345-020-03227-1 Spital Clinic. (2026, March). Declining testosterone levels by generation. https://www.spitalclinic.com Travison, T. G., Araujo, A. B., O'Donnell, A. B., Kupelian, V., & McKinlay, J. B. (2007). A population-level decline in serum testosterone levels in American men. The Journal of Clinical Endocrinology & Metabolism, 92(1), 196–202. https://doi.org/10.1210/jc.2006-1375 Low Testosterone — Mortality & Disease Risk Muraleedharan, V., Marsh, H., Kapoor, D., Channer, K. S., & Jones, T. H. (2013). Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes. European Journal of Endocrinology, 169(6), 725–733. https://doi.org/10.1530/EJE-13-0321 Shores, M. M., et al. (2006). Low testosterone associated with increased all-cause and cardiovascular mortality. Archives of Internal Medicine, 166(15), 1660–1665. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/410754 Yeap, B. B., Marriott, R. J., Dwivedi, G., et al. (2024). Associations of testosterone and related hormones with all-cause and cardiovascular mortality and incident cardiovascular disease in men. Annals of Internal Medicine. https://doi.org/10.7326/M23-2781 Endocrine Disrupting Chemicals Associations between endocrine-disrupting chemical exposure and fertility outcomes: A decade of human epidemiological evidence. (2024). PubMed Central (PMC12299029). https://pmc.ncbi.nlm.nih.gov/articles/PMC12299029/ Hayes, T. B., Haston, K., Tsui, M., et al. (2002). Herbicides: Feminization of male frogs in the wild. Nature, 419, 895–896. https://doi.org/10.1038/419895a Mechanisms of testicular disruption from exposure to BPA and phthalates. (2020). Journal of Clinical Medicine, 9(2), 471. https://pmc.ncbi.nlm.nih.gov/articles/PMC7074154/ Meeker, J. D., Calafat, A. M., & Hauser, R. (2014). Urinary phthalate metabolites and their biotransformation products: Predictors and temporal variability among men and women. Journal of Exposure Science & Environmental Epidemiology. https://www.sciencedaily.com/releases/2014/08/140814124330.htm Zhao, Q., et al. (2023). Male reproductive toxicity of microplastics: Head and tail of the sperm. Science of the Total Environment, 872, 162181. https://doi.org/10.1016/j.scitotenv.2023.162181 Zhong, B., et al. (2024). Mixed EDC exposure associated with reductions in testosterone and free androgen index. Scientific Reports. https://doi.org/10.1038/s41598-024-76972-z Cortisol, Stress & the HPG Axis Bielohuby, M., et al. (2012). Swiss military cadets prolonged stress study. Psychoneuroendocrinology. Preprints.org. (2025). Sleep deprivation: A modifiable cause. https://doi.org/10.20944/preprints202505.0580.v1 SiPhox Health. (n.d.). Summary of Journal of Clinical Endocrinology & Metabolism data. https://www.siphoxhealth.com Viau, V. (2002). Functional cross-talk between the hypothalamic-pituitary-gonadal and -adrenal axes. Journal of Neuroendocrinology, 14(6), 506–513. https://doi.org/10.1046/j.1365-2826.2002.00798.x Sleep & Testosterone Leproult, R., & Van Cauter, E. (2011). Effect of 1 week of sleep restriction on testosterone levels in young healthy men. JAMA, 305(21), 2173–2174. https://jamanetwork.com/journals/jama/fullarticle/1029127 Reiter, R. J., et al. (2021). Melatonin and male reproductive health: Relationship to oxidative stress, mitochondrial function, and Leydig cell protection. Endocrine. Tan, D. X., Hardeland, R., Manchester, L. C., et al. (2023). Melatonin as a pleiotropic antioxidant hormone. Journal of Pineal Research. Nutrition — Zinc, Vitamin D, Cholesterol Corona, G., et al. (2010). Statin therapy and testosterone levels in men: A systematic review. The Journal of Sexual Medicine. 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Welcome back to Truth, Lies & Work, the award-winning workplace podcast where behavioural science meets workplace culture, brought to you by the HubSpot Podcast Network. This week, hosts Al Elliott and Leanne Elliott unpack the sleep science taking over TikTok, a massive shift in how Google interviews tech talent, and the ethical dilemma of corporate accountability after a major cyberattack. Plus, we dive deep into the data to see if "years of experience" actually matters on a CV, and answer community questions from the experts at The Business Psycho.

Have you ever wondered why Capital One's approval decisions feel completely random - approval for some, denial for others, with almost no rhyme or reason?   Capital One has a well-earned reputation for being unpredictable with credit card approvals. When Katie from Katie's Travel Tricks saw the launch of the new Capital One Business Venture card, she decided to move beyond anecdotes and collect real data. She surveyed her audience about their approval and denial experiences, gathered nearly 150 responses, and analyzed the patterns using data to answer the questions everyone has been asking: what actually matters to Capital One?   Katie and I break down what her data revealed about the three strongest approval predictors, why the conventional wisdom about waiting six months between Capital One applications might not be accurate, which metrics matter (credit score, hard inquiries, pre-approval status) and which ones surprisingly don't, and how business structure (sole proprietor versus LLC) impacts your approval chances. We also discuss what role the Capital One Business Venture Card plays in your overall rewards strategy and how to think about it within the larger Capital One ecosystem.   Get full show notes and transcript: https://pointmetofirstclass.com/capital-one-approvals-data       Eager to learn the secrets of award travel so that you can turn your expenses into unforgettable experiences? Join the Points Made Easy course waitlist here: https://pointmetofirstclass.com/pointsmadeeasy