Join Dr Sanjeev Goel, as we explore the cutting edges of medical knowledge to "BE PEAK NOW"
In this episode of Peak Human Labs, Dr. Sanjeev Goel reconnects with Dr. Steph Venn-Watson, co-founder of Fatty15, to unpack the groundbreaking research behind C15:0—an odd-chain saturated fatty acid once overlooked, now emerging as a powerful longevity nutrient. What began as an accidental discovery while caring for aging Navy dolphins has grown into a movement to reimagine nutritional health and aging. From reversing cellular fragility and metabolic dysfunction to improving cognitive health and potentially slowing the progression of age-related diseases like Alzheimer's, this episode dives deep into what makes C15 so essential—and why most of us aren't getting enough. Ready to learn how a molecule you've never heard of could redefine your health span? Tune in now! Fatty15 and C15 Supplementation www.fatty15.com/drsanjeevgoel (Use code DRSANJEEVGOEL) Key Takeaways Discovery of C15 (pentadecanoic acid) through dolphin health research Role of C15 in reversing cellular fragility and ferroptosis Association between low C15 and conditions like anemia, fatty liver, and iron overload Differences between even-chain (e.g., C16) and odd-chain saturated fats How C15 improves red blood cell health and reduces aging biomarkers like RDW Sardinia's high C15 levels linked to longevity and heart health C15's presence in grass-fed dairy, especially pecorino cheese The supplement Fatty15 as a vegan-friendly, concentrated source of C15 Emerging research into C15's role in gut health, Alzheimer's, and cognitive protection Future applications in food fortification, pediatric nutrition, and global health policy In This Episode: [00:00:00] Why getting C15 into cells takes time [00:01:10] Introduction to guest Dr. Steph Venn-Watson and Fatty15 [00:02:31] Origins of the C15 discovery in Navy dolphin care [00:03:50] Metabolic disease and accelerated aging in dolphins [00:06:42] C15 identified as top predictor of healthy aging [00:09:27] C15's effectiveness confirmed in feeding studies [00:11:31] Corroborating human data on C15 and disease risk [00:14:14] Understanding ferroptosis and cellular fragility [00:17:35] How C15 lowers ferritin and liver iron overload [00:19:14] C15 blood levels and how much you need [00:20:49] Sardinia's lifestyle and natural C15 optimization [00:23:36] Supplementation potential vs. lifestyle changes [00:25:12] Navy-backed development of pure C15 supplement [00:27:09] C15's impact on aging biomarkers and RDW [00:28:45] Dog studies, gut health, and C15 in Alzheimer's research [00:31:52] Is Alzheimer's a disease of aging or longevity? [00:34:15] Why C15 may be the most promising geroprotector [00:37:52] Dosage, absorption timeline, and blood level targets [00:41:23] Future of C15 in nutrition policy and public health [00:43:46] The C15 content in eggs and Australian meats Our Guest Dr. Steph Venn-Watson is a veterinary epidemiologist, former Navy researcher, and co-founder of Fatty15. While studying aging dolphins, she accidentally uncovered the powerful health effects of C15:0, a molecule now recognized as a potential longevity nutrient. Her work bridges veterinary science, human medicine, and public health, with implications ranging from metabolic disease prevention to cognitive health and cellular stability. Her new book, The Longevity Nutrient, lays out the science, stories, and strategies to integrate this once-overlooked nutrient into modern life. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Steph Venn-Watson https://www.linkedin.com/in/stephanievennwatson/ https://fatty15.com/
In this episode of Peak Human Labs, Dr. Sanjeev Goel speaks with Chris Burres, scientist, entrepreneur, and co-founder of MyVitalC, to explore a breakthrough molecule known as ESS60. Originally used in industrial applications, ESS60 has now caught the attention of the longevity and wellness community after a study revealed that it could extend the lifespan of rats by up to 90%. Chris discusses the science behind ESS60, how it works at the mitochondrial level, and why it could be the most powerful antioxidant ever discovered. He also introduces the "BOSS" theory Buffering Oxidative Stress System which helps explain the molecule's wide-ranging benefits, including better sleep, reduced inflammation, and enhanced focus. Ready to learn about the molecule that could redefine aging and wellness? Tune in now! "Go to MyVitalC.com/PeakHuman and use Peak15 for 15% off" Key Takeaways Introduction to ESS60: its discovery and background Transformation from industrial to health applications How ESS60 works as a mitochondrial antioxidant Overview of the rat longevity study The BOSS Theory: how ESS60 buffers oxidative stress User testimonials: sleep, energy, inflammation, recovery The product's antioxidant capacity (125x–172x more than Vitamin C) Safety considerations, dosage, and use cases How ESS60 is excreted from the body Upcoming clinical research and real-world testing Ethical product manufacturing and quality control Chris's journey from nanomaterials to biohacking Growing awareness and future plans for MyVitalC In This Episode: [00:00:00] ESS60 as a stress buffer [00:01:06] Introduction to Chris Burres [00:02:19] Chris's background and transition into wellness [00:04:15] What is ESS60 and how it was discovered [00:06:06] The 2012 longevity rat study [00:08:22] How ESS60 works: Quantum behavior, atomic structure [00:11:17] Physiological effects and antioxidant mechanisms [00:14:55] Challenges in the supplement industry [00:17:09] ESS60 vs. Vitamin C as antioxidant [00:19:00] Hs-CRP reduction and inflammation studies [00:21:01] How ESS60 is processed and excreted [00:22:16] Recommended dosage and usage [00:23:27] The BOSS Theory explained [00:26:00] Anthony Kunkel's athletic performance testimonial [00:30:06] Role of melatonin and glutathione [00:33:15] Use in children and athletic youth [00:34:48] Head-to-toe health testimonials [00:35:17] Chris's goals for expanding awareness [00:36:34] Upcoming events and conferences [00:37:27] Purchasing and product details [00:39:45] Book, charity efforts, and final thoughts Our Guest Chris Burres is the co-founder of MyVitalC and a seasoned scientist in the field of carbon nanomaterials. With a background in mechanical engineering, Chris helped commercialize ESS60 and pivot it from industrial use to a consumer health product after groundbreaking longevity results. He is also the author of Live Longer and Better and is actively involved in health optimization and biohacking communities across North America. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Chris Burres SES Research: https://www.sesres.com/author/chrisburres/?srsltid=AfmBOorRIXvdAnQpedwd0M8Kgo2lAt6iU1UvQZPdlEMSXYRKjsBqdWLL LinkedIn: https://www.linkedin.com/in/chrisburres Instagram: https://www.instagram.com/chrisburres/ MyVitalC: https://www.myvitalc.com/product/live-longer-and-better/?srsltid=AfmBOookjQ2WKt16yMAOnHfkf5ZGx8XWJX9XK-YipOmZ94f0RNF75yJn
In this episode of Peak Human Labs, Dr. Sanjeev Goel sits down with Dr. Charles Nduka, a pioneering plastic surgeon and founder of Emteq Labs, to explore a breakthrough in wearable health tech—emotion-sensing eyewear. These cutting-edge glasses do more than just track facial expressions; they provide real-time insights into how emotions and dietary habits influence overall well-being. With potential applications for conditions like Alzheimer's and Parkinson's, this technology is set to revolutionize personalized healthcare by promoting mindful eating and uncovering the hidden connections between our emotions and food choices. Ready to discover how this innovation could transform the future of health and wellness? Tune in now! Key Takeaways Introduction of emotion-sensing eyewear technology Monitoring of facial expressions and dietary behaviors Real-time feedback on eating habits and emotional triggers Importance of diet and exercise in health and wellness Non-invasive technology for measuring facial muscle movements Applications for mental health and cognitive disorders Research collaborations for monitoring neurodegenerative conditions Personalized healthcare and proactive patient care Integration with existing health monitoring devices Future developments and community engagement in health technology In This Episode: [00:00:00] Introduction to emotion-sensing eyewear [00:01:10] Introduction of Dr. Charles Nduka [00:03:11] Technology behind emotion-sensing eyewear [00:04:03] Non-contact sensing technology [00:05:03] Functionality of the eyewear [00:05:59] Design of the glasses [00:06:41] Dietary behavior monitoring [00:08:58] Haptic feedback mechanism [00:10:15] Importance of chewing and digestion [00:11:06] Configurable feedback options [00:11:38] Self-management of eating habits [00:12:39] Image capturing while eating [00:13:51] Support for binge eating disorders [00:14:51] Gaze tracking vs. head movement tracking [00:16:04] Posture and emotion tracking [00:16:35] Research on depression detection [00:17:27] Application for neurocognitive illness [00:18:23] Measuring Parkinson's symptoms [00:19:00] Future of wearable technology [00:19:12] Launching developer desk [00:19:33] Diet-specific applications [00:20:43] Healthcare shift to home [00:20:49] Future of glasses design [00:21:29] Form factor necessity [00:22:20] Predictive functionality of glasses [00:22:44] Consumer launch timeline [00:23:18] Diet and blood glucose insights [00:24:07] AI food detection technology [00:25:00] Integration with existing health apps [00:26:00] Foundational role of diet [00:26:37] Team and company development [00:28:34] Community involvement call Our Guest Dr. Charles Nduka is the founder of Emteq Labs and a pioneering plastic surgeon specializing in facial paralysis treatments. With a deep understanding of facial expressions and their impact on well-being, Dr. Nduka has led the development of the world's first emotion-sensing eyewear—a groundbreaking innovation that captures the link between diet, emotional responses, and brain function. This cutting-edge technology is designed to provide insights into mental health conditions, Alzheimer's, and Parkinson's disease, revolutionizing how we monitor neurological and emotional well-being in real-time. Through Emteq Labs, Dr. Nduka is redefining the future of wearable health technology, empowering individuals with actionable data to enhance their daily lives. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Charles Nduka https://www.emteqlabs.com/ https://charlesnduka.co.uk https://www.instagram.com/charles.nduka/ https://www.linkedin.com/in/charles-nduka-53055218/
In this episode of Peak Human Labs, Dr. Sanjeev Goel sits down with Dr. Ryan Rossner, a former NFL player turned PhD researcher, now working at MiniCircle—a pioneering company developing the world's first reversible human genetic enhancement platform. Using highly expressive DNA plasmids, MiniCircle's innovative approach allows genes to be added to the body without altering the existing genome. Dr. Rossner delves into groundbreaking health optimization strategies, particularly gene therapy involving the follistatin gene, which enhances muscle growth, reduces inflammation, and supports rejuvenation. The conversation expands to other gene therapies, the role of sleep and exercise in longevity, and the importance of a holistic approach to health. They also explore cutting-edge longevity science, including hibernation's impact on metabolism, metabolic flexibility, and seasonal metabolic shifts. Dr. Rossner introduces the concept of metabolic elasticity—how an adaptable metabolism can extend lifespan. He breaks down key longevity mechanisms such as fasting, insulin regulation, and AMPK activation while highlighting promising research areas like ICAR and plasmapheresis. Throughout the discussion, he shares insights from his work at MiniCircle, offering a glimpse into the future of health and longevity interventions. Ready to dive deeper into the latest breakthroughs in longevity and health optimization? Subscribe now, share this episode with a friend, and stay tuned for more expert insights on Peak Human Labs! Key Takeaways Longevity and health optimization Gene therapy and its mechanisms Follistatin gene therapy for body composition and rejuvenation Accessibility and cost of gene therapy treatments Benefits of increased follistatin levels, including muscle growth and reduced inflammation Lifestyle factors contributing to longevity, such as sleep, exercise, and relationships Importance of self-monitoring and health-tracking tools Role of sleep in overall health and longevity In This Episode: [00:00:00] Introduction to the podcast [00:01:17] Guest introduction – Dr. Ryan Rossner [00:03:00] Mini Circle overview [00:03:37] Follistatin gene benefits [00:04:05] Gene therapy mechanism [00:04:57] Transfection process [00:05:22] DNA integration clarification [00:05:58] Follistatin level variation [00:06:44] Therapy duration [00:07:06] Accessibility of treatment [00:07:42] Future gene therapies [00:08:09] Clotho gene benefits [00:08:47] Patient treatment outcomes [00:09:30] Biological age measurement [00:09:43] Age reduction results [00:10:19] Personal experience in longevity [00:11:46] Pyramid of longevity [00:12:02] Individual variation in treatment response [00:12:18] Importance of sleep [00:13:10] Sleep and detoxification [00:13:44] Orexin receptor antagonists [00:14:20] Impact of aging on sleep [00:16:28] Weekly exercise routine [00:17:07] Recovery practices [00:20:59] Brain health insights [00:21:33] Supplements for brain health [00:21:52] Sauna and brain health [00:22:31] Hypoxia chamber experience [00:23:31] Research on hypoxia and longevity [00:24:47] Comparing oxygen levels [00:25:13] Creatine for brain benefits [00:26:01] Vitamin D and health [00:26:57] Rapamycin in longevity [00:27:48] Episodic use of rapamycin [00:30:17] Metabolic depression and triggers [00:31:64] Metabolic elasticity [00:34:03] Seasonal metabolism [00:35:06] Underappreciated longevity mechanisms [00:35:21] Genetic pathways and longevity [00:37:03] Interest in plasmapheresis [00:38:04] Future work at Mini Circle [00:38:38] Resources for learning Our Guest Ryan Rossner is a Ph.D. student in Molecular Medicine at the University of Washington, researching flavin-containing monooxygenase proteins in aging. Dr. Matt Kaeberlein, studies mechanisms of longevity and is a trainee in the Biological Mechanisms of Healthy Aging Program. As Director of Longevity Research at MiniCircle, he develops gene therapy platforms for health optimization. An active biohacker, he experiments with tools like altitude generators and ice baths. Rossner shares insights on aging and longevity through social media, contributing to the broader conversation on extending human potential. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Ryan Rossner https://minicircle.io https://www.instagram.com/rjrphd/
In this episode of Peak Human Labs, Dr. Sanjeev Goel, an expert in longevity and biohacking, converses with Dr. Mike Van Thielen, a PhD in holistic nutrition specializing in molecular hydrogen. They delve into the science and health benefits of molecular hydrogen, highlighting its role as a selective antioxidant that combats oxidative stress and inflammation. Dr. Van Thelen explains various methods of administration, including inhalation and hydrogen-rich water, and emphasizes the importance of using high-quality devices. The episode underscores the potential of molecular hydrogen in promoting wellness and encourages informed exploration of its applications. "Go to hydroheal.com and use coupon SG5 for a 10% discount on a hydrogen inhalation device" Key Takeaways Overview of molecular hydrogen (H2) and its unique properties. Mechanisms of action as a selective antioxidant. Health benefits associated with molecular hydrogen, include anti-inflammatory effects and immune system support. Promotion of autophagy and induction of apoptosis in damaged cells. Importance of mitochondrial health and energy production. Discussion on alkaline water and its relationship to hydrogen production. Evaluation of hydrogen generation devices and their quality considerations. Therapeutic applications of inhaled hydrogen for health benefits. Safety and efficacy concerns regarding hydrogen treatments. Resources for further learning about molecular hydrogen and its applications. In This Episode: [00:00:00] Introduction to molecular hydrogen [00:01:19] Focus on molecular hydrogen [00:03:35] Molecular hydrogen research [00:05:01] Understanding hydrogen [00:07:51] Hydrogen production in the body [00:08:28] Hydrogen deficiency [00:09:27] Hydrogen's antioxidant role [00:10:36] Hydrogen and free radicals [00:11:52] Hydrogen inhalation vs. water [00:12:29] Safety of hydrogen inhalation [00:13:01] Composition of inhaled hydrogen [00:14:15] Benefits beyond antioxidants [00:16:20] Autophagy and apoptosis [00:18:27] Neuroprotective effects [00:18:35] Personal experience with hydrogen [00:22:43] Conclusion on health benefits [00:22:44] The benefits of alkaline water and hydrogen [00:23:03] Hydrogen production methods [00:24:08] Electrolysis and device quality [00:24:49] Potential pitfalls of hydrogen equipment [00:25:09] Key features of quality hydrogen devices [00:26:27] Hydrogen for ear and skin conditions [00:27:06] Hydrogen in beauty products [00:27:58] Dr. Van Thelen's latest project [00:28:54] Future podcast on PMF Our Guest Dr. Mike Van Thielen is a Ph.D. in Holistic Nutrition, licensed Physical Therapist, Acupuncture Physician, and Doctor of Oriental Medicine with over 30 years of expertise in health optimization and biohacking. A former Olympic team coach and world-record-holding swimmer, he has earned 31 U.S. national titles. As an entrepreneur, Dr. Van Thielen founded anti-aging clinics and certified over 1,000 healthcare professionals in wellness programs. He is the author of Health 4 Life and Stem Cells 1-on-1 and has been featured on Fox, ABC, and NBC. A sought-after speaker, he has shared stages with Les Brown and Brian Tracy. Currently, he serves as Chief Medical Officer at ClariGenZ Health, helping individuals achieve peak performance through regenerative medicine and biohacking strategies. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Mike Van Thielen https://www.linkedin.com/in/mikevanthielenphd/ https://www.instagram.com/drmike_health4life/?hl=en https://www.amazon.com/stores/Mike-Van-Thielen-PhD/author/B09P8RH9KS?ref=ap_rdr&isDramIntegrated=true&shoppingPortalEnabled=true https://www.facebook.com/drmikeinspires/ http://hydroheal.com/
In this episode of Peak Human Labs, Dr. Sanjeev Goel is joined by Dr. Alex Ni, CEO of Divergence Neuro, for an insightful discussion on neurofeedback and brainwaves. They explore how neurofeedback utilizes brainwave data to enhance self-regulation and mental wellness, and how mobile EEG systems make neurofeedback accessible from home. Alex shares his journey from software development to neurofeedback, driven by personal necessity during the COVID-19 pandemic, and highlights the potential of this technology to improve mental health and cognitive function. Want to explore the benefits of neurofeedback? Visit Divergence Neuro to learn more today! Key Takeaways Neurofeedback as a mental health and wellness training modality. The significance of brain waves in self-regulation and cognitive function. Different types of brain waves: Delta, Theta, Alpha, Beta, and Gamma. The science and history of neurofeedback and its development. Measurement of brain waves using electroencephalography (EEG). Applications of neurofeedback in stress management and emotional regulation. The role of operant conditioning in neurofeedback training. The relationship between brain wave patterns and mental health issues like anxiety and addiction. Insights from animal studies on brain wave training and its implications for humans. In This Episode: [00:00:00] Introduction to neurofeedback and brain waves [00:00:52] Welcome to Peak Human Labs [00:01:36] Introduction to Dr. Alex Ni [00:02:03] Dr. Alex Ni's background and journey [00:03:16] Concept and importance of neurofeedback [00:05:18] Overview of brainwaves [00:07:25] Different brainwave states and their functions [00:09:39] Measurement of brainwaves using EEG [00:13:08] History of neurofeedback [00:17:19] Sensory motor rhythm (SMR) and its applications [00:20:10] Implications of SMR training on human conditions [00:21:42] Introduction to SMR and addiction [00:22:00] Understanding EEG signal [00:22:26] Training the brain with high-rate SMR [00:29:00] Applying operant conditioning for good [00:31:06] Building awareness of brain states [00:34:02] Generalizing learned skills [00:37:00] Benefits of neurofeedback training [00:39:00] The need for scalable mental health solutions [00:41:13] Introduction to divergence neuro-digital platform [00:41:38] Effectiveness and sustainability of neurofeedback [00:42:31] Overview of platform functionality [00:43:15] Growth in remote patient use [00:44:07] Advances in neurofeedback device design [00:45:09] New EEG device and its application [00:47:05] Effectiveness of neurofeedback training [00:49:41] Case study introduction [00:52:53] Brainwave markers and initial assessment [00:54:03] Continuous training results [00:56:00] Contact and referral information [00:57:33] Future developments in platform Our Guest Dr. Alex Ni is a startup founder, CEO, full-stack developer, and neurotech engineer with over 18 years of experience in software solutions and applied technical research. He is the CEO of Divergence, a company focused on improving mental health care with data-driven, neuro-integrated tools. Dr. Ni's mission is to make cognitive performance and mental health enhancements accessible through technology, offering portable, user-friendly neuro solutions that connect therapists and patients, while collaborating on data-driven research to validate treatments. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Alex Ni https://www.divergenceneuro.com/ https://www.linkedin.com/in/alexni/ https://x.com/alexdni?lang=en
Have you ever stopped to think about how the health of your skin might be the first indicator of your overall well-being? Could the antioxidants you're consuming be the key to preventing cellular damage and inflammation? In this episode of the Peak Human Labs Podcast, Dr. Goel sits down with Dr. Cory Goldberg, a leading plastic surgeon and longevity expert, to discuss the powerful connection between skin health and overall wellness. They dive into how antioxidants can help maintain youthful skin, the benefits of exosomes, and why skin health is such a clear indicator of your body's overall well-being. Dr. Goldberg also shares insights on "Beauty Span"—a holistic approach to beauty that goes beyond the surface. Plus, he offers expert advice on skincare, sun protection, and the surprising benefits of supplements like glycine and superoxide dismutase (SOD). Tune in to discover how you can improve both your skin and overall health. Don't forget to subscribe for more cutting-edge insights on health, longevity, and holistic well-being! Key Takeaways The relationship between antioxidants and overall health. The role of oxidative stress in aging and inflammation. The significance of skin health as an indicator of overall bodily wellness. The functions and potential applications of stem cells and exosomes in health. The impact of UV radiation on skin health and cellular damage. The effectiveness and limitations of topical antioxidants, particularly vitamin C. The importance of dietary sources of antioxidants and their practical limitations. The role of the enzyme superoxide dismutase (SOD) in combating oxidative stress. The concept of "beauty span" is a holistic approach to maintaining beauty through health. The connection between skincare practices and overall well-being. In This Episode: [00:00:00] Introduction to oxidative stress [00:00:33] Host introduction [00:01:17] Guest introduction [00:01:45] Dr. Goldberg's background [00:04:14] Stem cell functionality [00:05:51] Stem cell injection methods [00:09:54] Stem cells in joint treatment [00:10:50] Exosomes discussion [00:12:32] Risks of exosome use [00:13:30] Plant-derived exosomes [00:14:54] Senescent cells and skin health [00:16:10] Sun exposure and senescent cells [00:16:27] Reversibility of senescent cells [00:17:50] Bidirectional health and beauty [00:18:00] Importance of skincare [00:24:37] Dietary sources of antioxidants [00:25:55] Superoxide dismutase (SOD) Importance [00:27:45] Efficacy of antioxidants in studies [00:31:11] Genetic variability in SOD production [00:31:51] Glycerin supplement availability [00:32:38] Patient outcomes with glycerin [00:33:38] Research and studies on glycerin [00:35:39] Plans in longevity [00:37:14] Beauty span concept [00:37:41] Resources and contact information [00:38:33] Key takeaways from the episode Our Guest Dr. Cory S. Goldberg is a highly skilled plastic surgeon based in Toronto, specializing in a range of aesthetic procedures. With a background in Biomedical Engineering and Craniofacial Surgery, he offers cutting-edge treatments in breast augmentation, facelifts, rhinoplasty, and body contouring. Dr. Goldberg is renowned for his personalized approach to patient care and his use of advanced technologies, such as Vectra 3D Imaging, to ensure optimal results. His expertise is complemented by a strong commitment to enhancing both beauty and wellness, making him a sought-after choice for those looking to improve their appearance with precision and care. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Cory Goldberg https://www.corygoldbergmd.com/ https://www.youtube.com/c/drcorygoldberg https://www.instagram.com/drcorygoldbergmd/ https://www.linkedin.com/in/corygoldbergmd/?originalSubdomain=ca www.Beautyspan.com www.healthspan.digital www.GliSODin.org Products: ASCE Rose Cell Exosomes GliSODin
What if there was a powerhouse inside your body working tirelessly to fight off toxins, repair cellular damage, and keep you feeling your best? Enter glutathione—your body's master antioxidant, a vital player in detoxification and protection against oxidative stress. It's often referred to as the body's "silent warrior," but here's the catch: maintaining healthy glutathione levels isn't as simple as it sounds. In this episode of the Peak Human Labs Podcast, Dr. Goel sits down with Dr. Nayan Patel, a leading pharmacist and glutathione expert, to explore this incredible molecule's impact on human health. Dr. Patel dives into how glutathione functions as the ultimate detoxifier, its role in protecting against aging, and the challenges we face in boosting its levels. He shares his journey developing groundbreaking delivery systems, including a unique topical formulation that's changing the game. Plus, you'll hear firsthand patient success stories and insights into how regular glutathione supplementation can elevate your health. Ready to learn more about the key to longevity and vitality? Tune in now and discover how you can harness the power of glutathione in your life today! Coupon Code: PeakHuman10 for 10% off your order at Oral Wellness. Key Takeaways The importance of glutathione as a master antioxidant and detoxifier. The role of glutathione in human physiology and health. Challenges in increasing glutathione levels in the body. Dr. Patel's journey and research in glutathione delivery systems. Mechanisms of detoxification facilitated by glutathione. Various methods of glutathione supplementation (oral, intravenous, topical). Scientific evidence linking glutathione levels to health outcomes. The significance of cysteine in glutathione production. The impact of oxidative stress on health and chronic diseases. Future developments and product availability related to glutathione supplementation. Our Guest Dr. Nayan Patel, PharmD, is a renowned clinical pharmacist, researcher, and thought leader in glutathione and its role in health and longevity. He serves as an adjunct faculty member at the University of Southern California's School of Pharmacy and has authored The Glutathione Revolution, a book exploring the antioxidant's potential in cellular regeneration and health optimization. Dr. Patel has contributed to groundbreaking research on glutathione's impact on neurodegenerative diseases and brain health. He is a sought-after speaker at global medical conferences, blending scientific rigor with practical applications to promote well-being Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Nayan Pate https://www.linkedin.com/in/nayan-patel-pharmd/ https://www.amazon.com/Glutathione-Revolution-Disease-Increase-Antioxidant/dp/0306873974
In this episode of the PATH Podcast, I sat down with Dr. Sanjeev Goel, founder of Peak Human, to explore how you can reverse aging and reach your peak health. Dr. G shares his incredible journey from being a general practitioner to pioneering regenerative medicine and biohacking in Canada, combining cutting-edge science with mindfulness practices. We dive deep into the latest advancements in health optimization, from peptides and stem cells to testosterone replacement therapy (TRT) and growth hormone. Learn how these progressive technologies can help you extend your healthspan, not just your lifespan, and maintain vitality as you age. Topics Covered: Dr. Sanjeev Goel's Transition from Traditional Medicine to Regenerative Health The Difference Between Lifespan and Healthspan The Role of Peptides, Growth Hormone, and TRT in Longevity Reversing Biological Age and Optimizing Your DNA The Importance of Mindset and Mindfulness in Achieving Optimal Health Discover how Dr. G's holistic approach has helped countless people reclaim their health and learn how you can implement these transformative practices in your life.
What if you could optimize your health by understanding three critical factors influencing your body—testosterone, environmental toxins, and growth hormones? In this special AMA session, Dr. Sanjeev Goel dives deep into these topics, offering practical insights into their roles in vitality, longevity, and overall health. Whether it's demystifying the controversies around testosterone, tackling the hidden dangers of microplastics, or exploring the potential of growth hormone, this episode is packed with actionable advice for anyone looking to level up their health. Ready to take charge of your well-being? Tune in to uncover groundbreaking strategies for hormonal balance, detoxification, and smart aging today! Key Takeaways The role of testosterone in men and women, including benefits and risks. The hidden health impacts of microplastics and how to reduce exposure. Growth hormone: its effects on aging, body composition, and metabolism. Genetic factors influencing hormonal responses and how testing can help. Actionable tips for better hormonal health and detox strategies. In This Episode: [00:10] Introduction to the first-ever AMA [01:06] Testosterone: How it works and its importance [01:38] Debunking myths about testosterone and health risks [05:11] How testosterone affects energy, mood, and libido [07:29] Monitoring testosterone levels: total vs. free testosterone [12:07] Microplastics and their impact on weight and metabolism [17:26] Avoiding plastics: practical steps to minimize exposure [24:44] Growth hormone and its influence on longevity [29:18] The TRIM trial: Can growth hormone reverse biological aging? [33:11] Balancing growth hormone use for optimal health outcomes [35:42] Final thoughts: Practical advice on hormone health Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca
Could the answer to anxiety and sleep issues be found in a mushroom? Amanita muscaria, a unique and legal psychedelic, might be the breakthrough the mental health world has been waiting for. But what makes this mushroom so special? In this episode of the Peak Human Labs Podcast, Dr. Goel sits down with serial entrepreneur Alex Wolfe to explore the promising mental health benefits of Amanita muscaria, a legal psychoactive mushroom known for its calming and mood-enhancing properties. Alex, founder of Eons, shares how his company is at the forefront of microdosing technology, using muscimol—a unique compound that interacts with the brain's GABA receptors to promote relaxation and mental clarity. EON's innovative products, including a sleep aid and the new "Social Dose" (a safe, legal alternative to alcohol), are crafted to support mental wellness naturally and effectively. The conversation also highlights Eon's dedication to rigorous research, with an upcoming study involving veterans to deepen understanding of Amanita's therapeutic effects. Alex and Dr. Goel inspire listeners to consider natural options for mental wellness rooted in tradition and science. Try It Yourself: Ready to explore the benefits of Amanita muscaria? Head over to the Eons http://www.eons.com/ and use our special discount code: “peakhuman”. Key Takeaways Introduction to Amanita muscaria and its psychoactive properties. The importance of responsible psychedelic use for mental health. The innovative product was developed by Eons for legal psychedelic microdosing. The active ingredient muscimol and its effects on the brain. Comparison of muscimol's calming effects to traditional medications targeting GABA receptors. User experience and benefits of Amanita muscaria microdosing, including improved clarity and anxiety relief. Safety measures and recommended dosage for the product. Innovative delivery method using patented bioavailability technology for rapid absorption. Cultural significance and historical context of Amanita muscaria in various societies. Future product developments and the potential impact on mental health solutions. In This Episode: [00:37]Introduction to Alex Wolfe [01:05] Product reveal [01:34] Alex's background [01:54] Psychedelics and mental health [03:11] Types of mushrooms [04:45] Introduction to muscimol [05:15] Psychedelic effects explained [06:59] User experience with Muscimol [08:18] Research on micro-dosing [09:38] Amanita muscaria overview [10:03] Safety of amanita muscaria [12:57] Dosage discussion [14:05] Delivery method explained [16:21] Recommended usage [17:42] Long-term effects of use [18:45] Cultural significance of amanita muscaria [21:09] Product availability and pricing [21:57] Introduction to mental health solutions [22:16] Sleep product development [22:25] Addressing anxiety [22:49] Upcoming product: Social Dose [23:29] Feedback and experiences [24:01] Veteran study launch [24:26] Dr. Goel's experience with sleep product [25:10] Lifestyle supplement discussion [25:29] Discount code announcement [25:51] Conclusion and summary Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Alex Wolfe https://eons.com/ https://www.instagram.com/mr.alexwolfe/ Mentioned Book Microdosing with Amanita Muscaria
Hyperbaric Oxygen Therapy (HBOT) has increasingly gained recognition for its myriad health benefits. Many think of HBOT as a specialized medical treatment that involves breathing pure oxygen in a pressurized environment. This therapy, often performed in a hyperbaric chamber, significantly raises the oxygen levels in blood and tissues, offering a range of therapeutic benefits. In this episode of the Peak Human Labs Podcast, Dr. Sanjeev Goel sits down with Dr. Joseph Dituri, a retired Navy diver and expert in hyperbaric oxygen therapy. Dr. Dituri shares insights from his groundbreaking 100-day underwater experiment, which demonstrated remarkable health benefits, including reversing his biological age by 10 years. This conversation dives deep into the fascinating world of hyperbaric oxygen therapy, its impact on longevity, and how it can enhance physical and mental well-being. Dr. Dituri discusses the profound effects of hyperbaric oxygen on increasing telomere length, reducing inflammation, and boosting stem cell proliferation. He also reflects on his time underwater and its impact on his sleep, energy levels, and overall health. Whether you're interested in cutting-edge longevity research or just curious about the future of medical science, this episode has something for everyone. Key Takeaways How hyperbaric oxygen therapy works The potential for reversing aging Impact of hyperbaric therapy on telomeres, inflammation, and stem cells The connection between deep sleep and brain health Longevity practices and healing from within In This Episode: 00:00:00: Misconceptions about hyperbaric oxygen therapy 00:01:24: Introduction of Dr. Joseph Daturi 00:01:58: Overview of hyperbaric oxygen therapy and undersea stay 00:03:01: Dr. Daturi's background and involvement in hyperbaric research 00:04:28: Discovery of a potential Alzheimer's treatment 00:05:00: Reasons behind the 100-day undersea stay 00:06:39: Telomere lengthening through hyperbaric therapy 00:08:57: Impact of hyperbaric therapy on inflammation 00:09:43: Improved sleep and other biological effects during the undersea stay 00:14:33: Blood parameters and cortisol changes 00:16:00: Post-stay health changes and lasting effects 00:17:22: Implications and future of hyperbaric oxygen therapy 00:17:57: Overview of the problem with current medical treatments 00:18:32: Discussion on diseases related to inflammation 00:19:29: Feasibility of living in the ocean 00:20:07: Shift from traditional medical care to holistic approaches 00:21:21: Known benefits of hyperbaric therapy 00:22:02: Personal use of hyperbaric chambers 00:23:00: Oxygen therapy's mechanisms and health benefits 00:24:03: Plans and research on muscle size increase in zero gravity 00:25:23: Benefits of traveling in a hyperbaric state for space missions 00:26:28: Application to NASA and potential impact on space travel 00:27:02: Episode conclusion and summary with Dr. Joseph Daturi Our Guest As president of the Undersea Oxygen Clinic, Dr. Dituri has applied his Ph.D. in Biomedical Engineering to the development of a breakthrough treatment for healing Traumatic Brain Injury (TBI), Chronic Traumatic Encephalopathy (CTE), and the related symptoms of PTSD, depression, and long-term mental and physical impairments. Joseph Dituri is an American biomedical researcher and former Naval Commander. Also known as Dr. Deep Sea his research includes life support equipment design, high carbon dioxide environments, hyperbaric medicine, hyperbaric medicine, and traumatic brain injury. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Joseph Dituri https://drdeepsea.com/ https://www.instagram.com/drdeepsea/?hl=en https://x.com/drdeepsea?lang=en https://www.linkedin.com/in/joseph-dituri-ph-d-5099789/
There is stress that heals and sustains high performance, and there is stress that breaks you down. Discover the key pathways of stress to live your best life! Get the book by visiting https://www.mattsoule.com/book Stress can feel like an uninvited guest that overstays its welcome, impacting our health and performance in ways we often overlook. But what if you could transform that stress into a powerful tool for personal growth? In this episode of the Peak Human Labs Podcast Dr. Goel sits down with Matt Soule, a U.S.-based author and expert in the Wim Hof Method, which focuses on managing stress. Matt opens up about his journey of overcoming childhood trauma through martial arts and how it led him to embrace the Wim Hof Method. This powerful approach combines breathing exercises, cold exposure, and a strong mindset to enhance well-being and tackle stress head-on. Matt breaks down the method's key components, including energizing breaths that boost adrenaline, calming breaths for relaxation, and the importance of balanced breathing. He even shares a simple step-by-step breathing protocol that can help listeners experience benefits like improved oxygenation and mental clarity. Additionaly, he emphasizes the perks of cold exposure, which releases feel-good chemicals and builds resilience. Matt highlights the science behind the method, showcasing its ability to regulate stress hormones and reduce inflammation. He encourages everyone to dedicate just a few minutes daily to these practices. By embracing the Wim Hof Method, you can manage stress effectively and improve your overall well-being. For those interested, Matt offers resources like workshops and a free membership to help you master stress! Let's dive in! Key Takeaways Stress management techniques The Wim Hof Method Breathing exercises and their impact on stress Personal journey of overcoming childhood trauma Role of martial arts in stress relief Physiological benefits of cold exposure Importance of selecting beneficial stressors Anecdotes illustrating the effectiveness of the Wim Hof Method The relationship between health and high performance Resources for further learning and practice in stress management techniques In This Episode: [00:48] Matt Soule's background [02:29] Martial arts as stress relief [03:25] Transition to owning a martial arts school [05:07] Injury and discovery of the Wim Hof method [07:22] The importance of breath in healing [08:39] Overview of the Wim Hof method [10:02] Demonstration of breathing techniques [12:09] The three parts of the breathing protocol [13:09] Breath hold technique [16:00] Completing a breathing round [16:54] Daily practice recommendations [17:29] Understanding the 30-40 breaths [19:05] Chronic stress and breathing patterns [20:58] Comparison with other breathing traditions [21:07] Breathing techniques in the Wim Hof method [23:19] Breath control and adaptability [24:18] Scientific studies on Wim Hof method [27:17] Rapid benefits of Wim Hof method [30:35] Starting cold exposure practice [34:15] Risks of cold exposure [37:23] Contrast therapy with sauna and cold [40:20] Adaptation to cold over time [41:21] The benefits of cold exposure [42:07] Introduction to Matt's books [42:13] Stronger through stress [43:12] Personal success story [44:10] The stress paradox [44:53] Choosing the right stress [45:06] The necessity of stress [45:41] Resources for learning Our Guest Matt Soule is a U.S.-based author, speaker, and professional instructor dedicated to helping individuals leverage stress for peak performance. His journey began with childhood exposure to domestic violence, motivating him to combat stress through martial arts and the Wim Hof Method, where he became one of the first certified instructors in the U.S. Over 15 years, Matt has taught over 10,000 people and trained more than 600 instructors globally. He's the author of a book on mastering stress and is currently collaborating with Bradley Corporation on The Stress Paradox. Passionate about wellness, Matt leads workshops worldwide, impacting lives through innovative stress management strategies. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Matt Soule https://www.linkedin.com/in/mattsoule/ https://www.mattsoule.com/ https://www.mattsoule.com/wim-hof-method Mentioned Books Stronger Through Stress The Stress Paradox Unstressed
Click here for Nitric Oxide products https://n1o1.com/ and use “Peakhuman” as a coupon code for 10% off! Did you know that a tiny molecule could have a monumental impact on your health and well-being? Nitric oxide (NO) might be the unsung hero in your body, influencing everything from blood flow and exercise performance to disease prevention and recovery.But what makes this molecule so powerful? In this episode of the Peak Human Labs Podcast, Dr. Sanjeev Goel speaks with Dr. Nathan Bryan, a leading expert in nitric oxide physiology. They explore NO's crucial role in human health, including its impact on blood flow, circulation, and oxygen delivery. Dr. Bryan explains the two primary pathways of NO production: enzymatic synthesis from L-arginine and dietary nitrates converted by oral bacteria. They also discuss how diet, oral health, and medications like proton pump inhibitors influence NO levels. Additionally, Dr. Bryan introduces innovative NO supplementation strategies, highlighting their potential benefits for cardiovascular health and disease prevention. Tune in to discover how this remarkable molecule could be the key to enhancing your health. Key Takeaways Importance of nitric oxide (NO) in human health Mechanisms of nitric oxide production in the body Pathways of nitric oxide synthesis, including the role of nitric oxide synthase (NOS) enzymes Impact of diet and oral bacteria on nitric oxide levels Implications of nitric oxide deficiency on various health conditions Effects of dietary choices, particularly nitrates from vegetables, on nitric oxide production Relationship between endothelial function and nitric oxide Nitric oxide supplementation strategies and their effectiveness Pharmacokinetics of nitric oxide delivery methods Potential therapeutic applications of nitric oxide in treating diseases like ischemic heart disease and Alzheimer's disease In This Episode: [01:25] Dr. Bryan's background [03:13] Significance of nitric oxide [03:30] Misconceptions about nitric oxide [06:29] Mechanisms of nitric oxide production [08:20] Dietary influence on nitric oxide [09:34] Impact of oral bacteria [18:26] Antacids and nitric oxide deficiency [21:40] Young people and nitric oxide deficiency [22:55] Endothelial function and glycocalyx [24:17] Nitric oxide supplements [26:13] Introduction to nitric oxide [26:51] Mechanism of action [28:00] Restoring oral microbiome [29:01] Saliva and nitric oxide production [29:30] Dosage and frequency recommendations [31:25] Timing for optimal effects [32:22] Synergistic effects with medications [33:40] Tolerance and nitric oxide depletion [34:18] Details about Dr. Bryan's nitric oxide products and their benefits. [40:09] Conclusion and resources to learn more about nitric oxide. Our Guest Dr. Nathan Bryan earned his B.S. in Biochemistry from the University of Texas at Austin and his M.D. from Louisiana State University School of Medicine, where he received the Dean's Award for Excellence in Research. He completed post-doctoral training as a Kirschstein Fellow at Boston University's Whitaker Cardiovascular Institute. Recruited by Nobel Laureate Ferid Murad to the University of Texas Health Science Center at Houston, Dr. Bryan has pioneered nitric oxide research for 20 years, resulting in numerous patents and significant advancements in patient care. He is the Founder and CEO of Bryan Therapeutics, Inc., leading in nitric oxide-based therapies for various conditions. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr. Nathan Bryan https://drnathansbryan.com/ https://www.linkedin.com/in/nathan-bryan-27586b7/ https://www.youtube.com/results?search_query=dr+nathan+s+bryan https://web.facebook.com/humann/?_rdc=1&_rdr
In this inspiring episode, Dr. Goel sits down with Gaurav, who has achieved a remarkable weight loss of 150 pounds through his dedicated journey with Peak Human. Gaurav opens up about his transformative experience, the challenges he faced, and the incredible milestones he's reached along the way. His story is a powerful testament to the impact of personalized health strategies and determination. Whether you're looking for motivation or practical tips on your own health journey, this episode is a must-watch! Listen to the full podcast now and be inspired by Gaurav's incredible journey. You won't want to miss his valuable insights and tips for success!
They say aging is just a part of life, but have you ever wondered if it really has to be? What if getting older isn't just something we accept but something we could actually treat? In this riveting episode of Peak Human Labs Podcast, Dr. Sanjeev Goel, sits down with Dr. Aubrey de Grey, a trailblazing biomedical gerontologist and Chief Science Officer of the SENS Research Foundation. They dive deep into the revolutionary idea of treating aging as a medical condition. They explore how damage accumulates in our bodies over time and discuss the groundbreaking medical advancements that could extend our healthy lifespans. Dr. de Grey sheds light on the crucial need for investing in underfunded research and shares insights into the future of longevity science. Tune in and envision a future where health and longevity are not just aspirations but achievable realities! Click HERE to sign in for Dublin Longevity Declaration. Key Takeaways Aging as a medical condition versus a natural process Mechanisms of damage accumulation in the body Concept of "longevity escape velocity" Role of epigenetic changes in aging Importance of comprehensive interventions targeting different types of damage Current state of therapies for extending human lifespan Economic implications of aging therapies and preventative medicine Research on retroviruses and chronic infections in relation to aging Innovative therapies such as hyperbaric oxygen therapy and therapeutic blood exchange The significance of personalized health approaches and the microbiome's impact on longevity In This Episode: [00:00:00] Introduction to longevity research [00:00:51] Guest introduction [00:01:17] Personal connection [00:02:04] Dr. de Grey's background [00:03:14] Early research stages [00:04:05] Understanding aging as a machine [00:05:22] Accumulated damage mechanism [00:06:15] Comprehensive medical control [00:07:13] Categories of damage [00:07:55] Wear and tear concept [00:09:20] Epigenetic changes discussion [00:11:31] Partial reprogramming concept [00:13:30] Addressing multiple mechanisms [00:14:31] Longevity escape velocity [00:15:43] Initial pushback on longevity ideas [00:17:51] Positive outlook on aging research [00:19:51] The future of longevity research [00:20:54] Funding disparities in research [00:21:10] Business models in longevity research [00:21:58] Combining existing therapies [00:23:47] Current longevity therapies [00:24:56] Caloric restriction vs. drugs [00:25:36] Dublin Longevity Declaration [00:26:39] Community building through conferences [00:28:09] Anticipating longevity breakthroughs [00:29:12] Access to longevity therapies [00:30:58] Epigenetic clocks and age reversal [00:32:24] Retroviruses and aging [00:34:56] Persistent viral infections [00:37:24] Hyperbaric oxygen therapy [00:37:49] Therapeutic blood exchange [00:39:37] Discussion on active ingredients [00:40:41] Bone marrow transplant experimentation [00:42:09] Health benefits of bone marrow transplants [00:43:05] Personal health practices [00:43:55] Advice for maximizing healthy lifespan [00:45:01] Microbiome and longevity Notable Quotes [00:03:14] "The idea that anyone could ever think that aging was just something we should accept has never made any sense to me at all." — Dr. Aubrey de Grey [00:14:31] "I believe we need to get to about 20 years of postponement of the health problems of late life, which I think we might be able to achieve in the next 12 to 15 years." — Dr. Aubrey de Grey [00:25:36] "Not only are they my favorite parts of the year, but also they are absolutely the fulcrum, the centerpiece of all of my community building effort." — Dr. Aubrey de Grey [00:43:36] "I can eat exactly what I like and nothing ever happens, and I don't even need to do any exercise and I still stay fit, so you know, don't do as I do, do as I say." — Dr. Aubrey de Grey [00:43:55] "Everybody's metabolism has its own strengths and weaknesses, and so honestly, the only generic advice that I feel that one can give in terms of maximizing one's healthy lifespan is to pay close attention to your body." — Dr. Aubrey de Grey [00:44:28] "I honestly can see a strong argument for just recommending to absolutely everybody that they should eat gluten-free food for like a fortnight, just to see whether they feel different." — Dr. Aubrey de Grey Our Guest Dr. Aubrey de Grey is a biomedical gerontologist and founder of the LEV Foundation, focused on repairing aging-related cellular damage. Based in Silicon Valley, he earned his BA in computer science and Ph.D. in biology from the University of Cambridge. His research targets the characterization and repair of aging damage. A Fellow of the Gerontological Society of America and the American Aging Association, he advises numerous journals and organizations and is a sought-after speaker at scientific and public events. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724 Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca Dr Aubrey de Grey https://www.levf.org/ https://www.linkedin.com/in/aubrey-de-grey-24260b/ https://web.facebook.com/aubrey.degrey/?_rdc=1&_rdr
Dr Goel interviews Dr Steph about this remarkable C:15 fatty acid called Fatty 15 To get your 20% discount on Fatty15 click here In this fascinating conversation with Dr. Steph, we delve into the discovery of an essential fatty acid, C15:0 pentadecanoic acid, and its profound impact on health and aging! Dr. Steph shares about her journey in creating Fatty15, and how her research in the navy dolphin's health led to the revelation that dolphins with higher levels of C15:0 experienced healthier aging, similar to humans. This odd-chain saturated fat, once overlooked due to a bias against all saturated fats, has shown to be crucial in preventing chronic inflammation, fatty liver disease, and potentially Alzheimer's disease. While the primary source of C15:0 for humans is whole dairy fat, the conversation also touches on the implications for vegans and the need for supplementation. Furthermore, C15:0's role in cellular integrity and its potential to combat various diseases, including cancer, is discussed. The interview also explores the upcoming availability of at-home C15:0 tests and the importance of maintaining adequate levels for overall health. Dr. Steph highlights the ongoing research into C15:0's benefits for brain health and its potential applications in canine longevity. The discussion concludes with an emphasis on the importance of this fatty acid, not just for humans but for our mammalian counterparts as well. You can discover more about C15:0 and the Fatty15 supplement at an DiscoverC15.com and Fatty15.com
Join Dr. Sanjeev Goel and seasoned biohacker Sol-Pal John Bejarano in a deep dive into the world of biohacking. Sol-Pal shares his inspiring journey of age reversal, motivated by his father's stroke. Discover the crucial role of education, diet, supplements, and stress management in aging gracefully. Sol-Pal's approach tackles the 12 Hallmarks of Aging through a personalized regimen, offering practical tips for stress management and health optimization. Learn about Sol-Pal's meticulous tracking methods and how they enhance health without sacrificing productivity. Dive into the world of biohacking with this insightful discussion! TIMESTAMPS: 00:00 - Intro 00:40 - Background and motivation 05:24 - Starting the biohacking journey 06:17 - Addressing genomic instability 08:01 - Managing chronic stress 11:46 - Tracking routines and staying productive 13:39 - Addressing telomere attrition 15:05 - Intro to magnesium 17:30 - Types of magnesium and dosage 20:26 - Tracking biomarkers and biological age 23:30 - Balancing diet for longevity 26:04 - Success stories in biohacking 30:01 - Functional medicine doctor recommendation 30:19 - Future of biohacking movement 32:28 - Biohacking worldwide 34:43 - Importance of coaching 35:36 - Starting your biohacking journey 37:17 - Basic supplements 41:58 - Precision supplements 42:40 - Closing remarks Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Link to Study https://jamanetwork.com/journals/jama...
Join Dr. Sanjeev Goel and Dr. Anil Maheshwari in a deep dive into cardiovascular health, discussing key risk factors, advanced lipid tests, and the importance of individualized care. Learn about cholesterol markers, genetic influences, and lifestyle modifications that can lower cardiovascular risk. Gain insights into the complexity of heart health and the latest advancements in cardiovascular care. TIMESTAMPS: 00:00 - Intro 01:21 - Advocating for Your Health 03:45 - Ethnicity and Cardiovascular Risk 05:05 - Family History and Cardiovascular Risk 07:05 - LDL (Low-Density Lipoprotein) 10:32 - LDL Guidelines 12:51 - Oxidized LDL 14:03 - HDL (High-Density Lipoprotein) 16:33 - Total Cholesterol to HDL Ratio 19:54 - Triglycerides and Non-HDL Cholesterol 21:49 - Apolipoprotein B (APO B) and Lipoprotein A (Lp(a)) 24:21 - Lipoprotein A (continued), Genetic Risk, and Medication Considerations 30:13 - High Sensitivity CRP (hs-CRP) and Inflammation 33:15 - Additional Tests and Medication Options 36:02 - Conclusion Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs * Link to Study https://jamanetwork.com/journals/jama...
Join Dr. Sanjeev Goel in discovering the transformative power of heart rate variability (HRV) with Dr. Torkil Færø as he delves into his book, "The Pulse Cure." Learn how personalized approaches and Garmin's tracking technology can optimize your HRV. Dr. Færø shares insights on improving sleep, diet, and exercise for better health. Hear success stories and explore the future of preventive medicine through HRV customization. Tune in to this episode for actionable tips on enhancing your well-being and longevity. TIMESTAMPS: 00:00 - Intro 01:36 - Intro of Dr. Torkil Færø 03:24 - Background of Dr. Færø 05:51 - Importance of Heart Rhythm 08:35 - Tracking HRV 09:55 - New Wearable Technologies 10:51 - Aging and HRV 12:57 - Impact of Alcohol on HRV 14:48 - Success Stories 16:54 - Future Research 18:04 - Understanding Stress and Recovery 21:51 - Utilizing Technology for Health Monitoring 29:25 - Importance of Rest and Recovery 34:33 - Conclusion Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs * Link to Study https://jamanetwork.com/journals/jama...
In this video, Dr. Sanjeev Goel and Vyom Goel delve into the topic of mental health, focusing on the importance of mindfulness. They discuss how mindfulness isn't about stopping thoughts but rather being aware of them without judgment. They guide viewers through a simple mindfulness exercise, highlighting the benefits of taking a moment for oneself. Whether you're new to mindfulness or looking to deepen your practice, this episode offers practical tips and techniques to help you on your journey to greater mental well-being. TIMESTAMPS: 00:00 - Intro 00:15 - Importance of Mindfulness 01:52 - Challenges in Practicing Mindfulness 04:19 - Mindfulness Exercise Demonstration 06:26 - Conclusion Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs * Link to Study https://jamanetwork.com/journals/jama...
Join Dr. Sanjeev Goel from Peak Human Labs as he explores the potential of liquid biopsies for early cancer detection. Learn how these blood tests could revolutionize cancer screening by identifying cancerous signs before tumors develop. Discover the benefits, limitations, and future possibilities of this cutting-edge technology. TIMESTAMPS: 00:00 - Introduction 00:15 - Multi-Cancer Detection Test 01:45 - Potential Benefits and Drawbacks 02:25 - Accuracy and False Positives 03:38 - Prostate Specific Antigen Test 04:45 - Future of Cancer Screening 05:42 - Availability and Cost 06:14 - Conclusion Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs ******************** Link to Study https://jamanetwork.com/journals/jama...
Join Dr. Sanjeev Goel and Dr. Sanjiv Chopra, a renowned hepatologist and Harvard Medical School professor, as he delves into the realms of leadership and purpose. Dr. Chopra shares profound insights from his own journey, stressing the significance of aligning actions with personal purpose. Discover the four pillars of happiness he advocates for meaningful relationships, forgiveness, altruism, and gratitude. Dr. Chopra's discussion offers practical wisdom for those seeking fulfillment and clarity in their lives. He also touches on his forthcoming book, "Letters to a Young Doctor," which explores alternative career paths for physicians. Dive into this engaging conversation filled with valuable life lessons and professional guidance. TIMESTAMPS: 00:00 - Intro 01:20 - Dr. Sanjiv Chopra's background 03:54 - Dr. Chopra's journey into leadership 07:03 - Discovering purpose in life 13:02 - Importance of defining personal purpose 16:19 - Example of defining purpose (Elena Sotoor) 17:53 - Advice for finding purpose 18:05 - Importance of gratitude 19:00 - Purpose in life 21:30 - Story of Papa Jaime 26:44 - Breakthroughs in Medicine 34:01 - Gut microbiome 38:03 - Safe amount of alcohol 38:10 - Letters to a Young Doctor (Book) 39:12 - Abraham Verghese and "The Covenant of Water" 40:02 - Inspiring stories of Physicians turned Authors 40:49 - Advice to young doctors 42:54 - Lifelong learning 47:08 - Future of Medicine 52:34 - Hope and Aging 57:21 - Conclusion Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE ON YOUTUBE: https://bit.ly/PeakHumanLabs Link to Study https://jamanetwork.com/journals/jama...
Join Dr. Sanjeev Goel in an interview with Dr. Raghav Sehgal, a PhD student at Yale and expert in epigenetic clocks. Discover how Dr. Sehgal's research sheds light on aging, from predicting chronological age to understanding the pace of aging and mortality risk. Learn about the concept of "systems age" and how different organs age at varying rates, impacting disease prevalence. Explore the potential for personalized treatments based on these findings. Dr. Sehgal also discusses the impact of lifestyle factors like diet and exercise on reversing epigenetic aging, offering practical insights for a healthier, more youthful life. TIMESTAMPS: 00:00 - Introduction 01:05 - Background and Entry into Epigenetic Clocks 09:03 - History of Epigenetic Clocks 17:00 - Systems Age: Measuring Aging in 11 Organs 19:02 - Importance and Significance of Systems Age 20:04 Aging Clusters 22:26 Cardiovascular Disease Clusters 24:56 Impact of Alcohol on Aging 27:52 Reversibility of Epigenetic Clocks 30:11 Impact of Diet on Aging 35:43 Personalized Recommendations 38:51 Exercise and Longevity 39:31 Availability of Systems Clock 40:05 Future Projects Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ Subscribe on Youtube: https://bit.ly/PeakHumanLabs Link to Study https://jamanetwork.com/journals/jama...
Join Dr. Sanjeev Goel and Carmelia Ray as they delve into the world of popular diets. From intermittent fasting to the South Beach Diet, Atkins, and the Raw Food Diet, they provide insights, tips, and considerations for each approach. Discover the pros and cons, the science behind them, and practical strategies for incorporating healthier eating habits into your lifestyle. Whether you're curious about weight loss, metabolic health, or simply optimizing your well-being, this podcast episode offers valuable information to help you make informed choices about your diet. ******************** TIMESTAMPS: 00:00 - Intro 00:28 - Discussion on different diets 03:13 - Intermittent Fasting 10:38 - South Beach Diet 12:13 - Atkins Diet 16:22 - Raw Food Diet 20:50 - Closing Remarks Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs ******************** Link to Study https://jamanetwork.com/journals/jama...
Join Dr. Sanjeev Goel and Dr. Anil Maheshwari as they unpack the Netflix Documentary “you are what you eat” examining a study comparing vegan and omnivore diets. Discover surprising insights into LDL cholesterol levels, calorie intake, and muscle mass differences between the groups. Explore the study's design nuances, exercise protocols, and participant selection processes, raising critical questions about result reliability. Gain insights into potential anti-aging effects and reflections on dietary choices' impact on overall health. Tune in for a thought-provoking discussion that delves into deeper questions about well-being. TIMESTAMPS: 00:00 - Intro 01:11 - Study Design Overview 04:03 - Results Summary 10:02 - Discussion on Muscle Mass 12:56 - Exercise Protocol Variations 15:17 - Participant Demographics 16:14 - Vegan Group Findings 20:55 - Research Methodology 27:12 - Comparative Analysis of Diets and Results 31:54 - Closing Remarks Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE on Youtube: https://bit.ly/PeakHumanLabs ******************** Link to Study https://jamanetwork.com/journals/jama...
Discover the ancient art of fermentation with Dr. Sanjeev Goel in this journey through time and science. From the origins of fermentation to its profound health benefits, unlock the secrets behind this age-old process. Learn how fermentation preserves food, enhances nutrition, and boosts immunity, while exploring its delicious possibilities. Join us in embracing the power of nature's fermentation for a healthier lifestyle. TIMESTAMPS: 00:00 - Introduction 00:12 - History of Fermentation 01:00 - Science of Fermentation 02:00 - Benefits of Fermentation 03:01 - Improved Digestion 04:13 - Boosted Immunity 05:13 - Mental Health Benefits 06:15 - Diverse Gut Microbiome 07:06 - Conclusion Visit our website: https://peakhuman.ca Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs
Join Dr. Sanjeev and leading neuroscientist Dr. Nicole Avena as they uncover the hidden dangers of sugar consumption in this engaging discussion. Dr. Avena sheds light on the addictive nature of added sugars in processed foods, urging viewers to be mindful of their sugar intake and offering practical strategies to combat cravings. Gain insights into the impact of sugar on our brain's reward pathways and learn how to foster healthier dietary habits for yourself and your family. Don't miss out on this insightful conversation about sugar addiction and its effects on overall health. TIMESTAMPS: 00:00 - Introduction 01:41 - Evolution of Research Interests 03:03 - Understanding Sugars 04:11 - Effects of Sugar Consumption 06:37 - Fruit Sugar vs. Added Sugar 07:57 - Impact of Fruit Juicing 09:49 - Monitoring Sugar Intake 10:50 - Changes in Food Industry 11:54 - Effects of Sugar on Brain Reward Pathways 17:04 - Tolerance & Binging 18:09 - Sugar Addiction & Binge Eating 19:30 - Sugar & Mental Health 20:44 - Understanding Tolerance 22:09 - Sugar Withdrawal Symptoms 23:52 - Cravings & Hedonic Cravings 26:29 - Coping with Sugar Cravings 28:01 - Understanding Dopamine Release 29:06 - Impact of Sugar Substitutes 32:04 - Effects of Reducing Sugar Intake 35:03 - Parenting Approach to Sugar 37:29 - Starting the Journey to Reduce Sugar 40:57 - Closing Remarks
In this episode, Dr Goel discusses the availability of a new blood test to diagnose Alzheimer's disease called the p tau217 antibody test. Plus, explore advanced cognitive screening methods now available, offering insights into mild cognitive impairment years before Alzheimer's onset. Stay informed, engage with us in the comments, and together, let's pave the way for prevention and breakthroughs in Alzheimer's research. TIMESTAMPS: 00:00 - Introduction 00:32 - New Blood Test: The P Tau217 Antibody 01:57 - Expanded Testing Options: Cognitive Function Screening 03:57 - Understanding Mild Cognitive Impairment (MCI) 04:51 - Importance of Early Screening and Prevention 05:58 - Conclusion
Unlock the mysteries of alcohol's impact on health with Dr. Sanjeev Goel from Peak Human Labs. In this video, explore the history of alcohol and its metabolic pathways, unraveling its effects on vital organs like the liver, muscles, and brain. Dr. Sanjeev delves into the emotional impact, explaining how alcohol influences GABA and dopamine pathways. TIMESTAMP: 00:00 - Introduction 00:26 - Brief background on alcohol 02:05 - Metabolism of alcohol 03:47 - Impacts on the liver 05:29 - Effects on muscles and performance 07:28 - Fatty liver and fat storage 09:28 - Brain impacts and neurotransmitters 12:13 - How alcohol impairs judgment 13:37 - Chronic ingestion vs. acute ingestion 14:54 - Stimulating GABA and dopamine 16:00 - Effects of alcohol on brain cells 17:06 - The CAGE questionnaire 17:25 - Personal experience with alcohol-free lifestyle 18:13 - Closing remarks
In this video, Join Dr. Sanjeev Goel from Peak Human Labs and his special guest, Dr. Anil , as they dissect the Netflix documentary "You Are What You Eat." In this episode, they discuss the first two episodes of the series and provide insights on nutrition and its impact on health. Don't forget to like and subscribe to their channel to support their work. Main Takeaways: - The first two episodes are discussed in detail, focusing on the relationship between nutrition and health. - Viewers are encouraged to like and subscribe to the channel to support the creators and increase visibility. To gain valuable insights into nutrition and its impact on health, watch the dissecting of the "You Are What You Eat" documentary on the Peak Human Labs YouTube channel. Like and subscribe to stay updated with their latest content.
Dr. Goel from Peak Human Labs explores the science behind alcohol use and its impact on the brain and body. As many people participate in dry January, Dr. Goel discusses the traditional belief that moderate alcohol consumption is healthy and examines conflicting studies that suggest even small amounts of alcohol can be harmful. Join Dr. Goel as he delves into the data, revealing the true effects of alcohol on our health. Main Takeaways: - Traditional guidelines once stated that moderate alcohol consumption, such as one or two drinks a day, was healthy and associated with better health outcomes. - However, recent studies and a meta-analysis of 4.8 million people have shown no benefit to drinking less than two drinks a day. - Conflicting studies exist regarding the potential harms of even small amounts of alcohol, with some individuals being allergic and experiencing adverse effects. Discover the science behind alcohol use and its impact on your health. Join Dr. Guo as he separates fact from fiction. Stay informed and make educated choices about your alcohol consumption for a healthier lifestyle. Contact Information:
In this episode, Dr. Sanjeev Goel delves into the fascinating world of methylene blue, an age-old supplement with newfound potential. Discover its history, uses, and why it's making a comeback in the world of anti-aging and Alzheimer's treatment. Learn about its safe dosage, mechanisms, and where to get it. Take charge of your health and well-being with methylene blue! TIMESTAMPS: 00:00 - Introduction 00:13 - Historical Uses of Methylene Blue 01:15 - Benefits of Methylene Blue 02:30 - Dosage and Mechanism of Action 03:05 - Conclusion
In this episode, Dr. Sanjeev Goel shares his top three essential supplements for optimal health. Discover the importance of nitrate supplements for blood vessel dilation, the rejuvenating effects of TA65 on your immune system, and the benefits of phosphatidylcholine for brain and liver health. Don't miss his supplement recommendations for each!
Join Dr. Goel from Peak Human as he discusses the choice between Ozempic and Mounjaro for weight loss in response to a viewer's question. Learn about the differences in dosages, side effects, and mechanisms of action between these medications. Discover if switching to Mounjaro is the right decision for you. Don't miss out on valuable insights into managing your weight and health. Subscribe for more expert advice from Dr. Goel. TIMESTAMPS: 00:00 - Introduction 00:16 - Viewer's Question 01:11 - Ozempic vs. Mounjaro 02:07 - Dosage Comparison 03:12 - Mechanism of Action 04:04 - Conclusion
Learn about Testosterone Replacement Therapy (TRT) and Estrogen Blockers with Dr. Sanjeev Goel. If you're considering TRT, understanding how your body metabolizes testosterone is crucial. Dr. Sanjeev explains the pathways, enzyme variations, and factors like BMI that impact your hormone balance. Discover if an estrogen blocker is right for you. Subscribe for more valuable insights!
In this episode, Dr. Sanjeev Goel explores the significance of quality sleep as one of the top biohacks of 2023. He highlights the role of sleep in memory consolidation and its potential brain detoxification effects. Practical tips are shared, including avoiding bright lights, refraining from late-night exercise and caffeine, and steering clear of late meals. Wearable technology like the Oura Ring is discussed for sleep tracking, and the benefits of blue light-blocking glasses and relaxation techniques are touched upon. Grab Dr. Sanjeev's book, "The Top 10 Must-Do Peak Human Biohacks of 2023," for more insights. TIMESTAMPS: 00:00 - Introduction 00:15 - Importance of Sleep 01:20 - Sleep and Brain Function 02:00 - Glymphatic System 03:01 - Sleep Duration and Quality 03:43 - Factors Affecting Sleep 05:00 - Impact of Technology and Light 06:00 - Blue Light Blocking Glasses 07:01 - Avoid Vigorous Exercise at Night 08:00 - Avoid Caffeine and Alcohol 10:00 - Avoid Eating Late 12:22 - Music and Meditation for Sleep 13:00 - Conclusion
Discover the Science Behind Intermittent Fasting with Dr. Sanjeev Goel! Learn about the incredible health benefits, from improved insulin sensitivity to brain health. Find out why it's more than just a weight loss method. Get expert advice on starting with a 12-hour fasting window and optimizing your health. Explore the natural approach to eating that aligns with your body's rhythms and consider the right fasting window for you. Join us on a journey to better health! *** TIMESTAMPS*** 00:00 - Introduction 00:18 - Fasting Terminology 02:31 - Metabolic Benefits 05:09 - Insulin Sensitivity & Brain Health 07:58 - Cardiovascular Health 10:18 - Recommendations & Adaptation 15:01 - Insulin overshoot 18:03 - Who should avoid fasting 20:57 - Impact of eating times on sleep 21:10 - Effects on gut bacteria and metabolites 22:17 - Autophagy and its benefits 24:25 - Overall benefits of fasting 25:53 - Potential for increased longevity 26:36 - Conclusion
Join Dr. Sanjeev Goel and Dr. Momchilo Vuyisich, Chief Science Officer of Viome, as they explore Viome's groundbreaking approach to personalized health through microbiome and RNA expression. They discuss the importance of gene expression in understanding health and Viome's recent clinical achievements in managing pre-diabetes. Learn how microbiomes fit into the broader health spectrum and the potential role of fungi in chronic diseases. Learn more about Viome: https://viomehq.sjv.io/c/4997402/1885... ***TIMESTAMPS*** 00:00 - Introduction 01:01 - Dr. Momchilo (Momo) Vuyisich's background 10:43 - Development of technology 16:08 - Importance of saliva 17:57 - Mention of Alzheimer's, Parkinson's, and type 2 diabetes 19:01 - Collecting various samples for analysis. 20:10 - Analyzing gene expression. 22:04 - Explaining gene expression. 23:25 - The importance of gene expression in health. 24:50 - Gene expression in the gut microbiome. 27:11 - Stability of gut microbiome gene expression. 28:57 - Microbial community interactions. 30:16 - Gut microbiome, serotonin, and mental health. 31:42 - Measuring RNA expression. 33:38 - Fungal involvement in chronic diseases. 36:00 - Biofilms and health impacts 36:59 - Fungi's role in pancreatic cancer 37:26 - Presence of fungi in ALS patients 38:04 - Benefits of Saccharomyces boulardii probiotic 39:05 - Organic foods and pesticides 41:00 - Microbiome testing methods 42:15 - Role of RNA expression in analysis 45:05 - Application of RNA expression in ecosystems 47:17 - Viome's full body intelligence test 48:58 - Food sensitivity testing with EverlyWell 52:59 - Conclusion
Join Dr. Sanjeev Goel and Neeraj Jain as they explore critical red flags in long-term partnerships. Learn about evaluating family dynamics, maintaining friendships, health, and daily routines. Discover how owning cats can affect personality traits. Spot warning signs like excessive sleeping, financial instability, and more. Gain valuable insights for making informed decisions in your relationships.
In this episode, Dr. Sanjeev Goel and Dr. Varun Dwaraka, Head of Bioinformatics at TruDiagnostic, discuss biologic age testing, focusing on DNA methylation and epigenetics. They explore how epigenetic changes occur with aging, affecting gene expression. The conversation touches on the history of epigenetic clocks, aiming to predict biological age beyond chronological age. They introduce the DunedinPACE Clock, which shows promise in improving accuracy. TruDiagnostic's OM Clock integrates various data layers, providing a comprehensive aging assessment. It predicts health outcomes with higher sensitivity and specificity than existing clocks and undergoes ongoing research for response to interventions. For more details, visit www.trudiagnostic.com or connect with Dr. Varun Dwaraka on LinkedIn or Instagram. Varun Dwaraka PhD is the Head of Bioinformatics at TruDiagnostic, and an aging and longevity investigator specializing in epigenetics and bioinformatics. He has co-authored numerous publications relating to genetics, epigenetic clocks, DNA methylation, and tissue regeneration. In 2020, Dr. Dwaraka was elected as a full member to the Sigma Xi, The Scientific Research Honor Society, and currently serves as a 2023 Foresight Fellow in Biotechnology and Health Expansion, awarded by the Foresight Institute. He also serves on the Scientific Advisory Board for SRW Labs based in New Zealand, offering insight into the application and interpretation of epigenetic age biomarkers. Dr. Dwaraka is passionate about implementing machine learning methods to advance predictive medicine, identify novel biomarkers, and create algorithms to better understand the biology of aging.
In this episode, join Dr. Sanjeev Goel as he delves into the fascinating science behind amyloid beta deposition and its connection to Alzheimer's disease. Discover the historical origins of Alzheimer's research, the role of genetic mutations in amyloid buildup, and the intricate cascade of events that lead to neuroinflammation and cognitive decline.
Join Dr. Sanjeev Goel from Peak Human Labs and Neeraj Jain as they delve into the topic of testosterone replacement therapy. They discuss the signs of declining testosterone levels, the importance of consulting a doctor for a blood test, and the various methods of testosterone replacement, including injections and topical applications. Dr. Goel explains potential side effects and nuances to consider, emphasizing the importance of personalized medical advice. They also tease future discussions about natural ways to boost testosterone and the effectiveness of supplements like Tongkat Ali and Ashwagandha. If you found this episode helpful, don't forget to like, share, subscribe, and leave your comments. Stay tuned for more insightful content on hormone health! Continue to Be Peak!
Join Dr. Sanjeev Goel and Carmelia Ray as they discuss recent developments in Alzheimer's research and the aging process! Dr. Goel shares his PET scan results, revealing no amyloid deposits despite having the APOE4 allele, challenging the notion that it always leads to Alzheimer's. They also explore the dual effects of APOE4 on health, emphasizing the role of lifestyle factors in mitigating risks. This episode introduces the concept of senescence, where aging cells become dormant and contribute to inflammation and aging. They discuss potential therapies targeting senescent cells to combat aging. Be sure to like, comment, and share with a friend! Continue to Be Peak!
Join Dr. Sanjeev Goel and Carmelia Ray in this insightful discussion about Hormone Replacement Therapy (HRT). They talk about menopause, various ways of taking hormones, the benefits and much more. Please like, share and subscribe to our podcast!
Join Dr. Sanjeev Goel in an engaging conversation with Panos Papadiamantis from PNoE, a pioneer in advanced metabolic testing.
In this episode, join Dr. Sanjeev Goel and Carmelia Ray where they introduce "Peak Canine," a revolutionary initiative aiming to provide human-level care for dogs. The duo discusses the inspiration behind this project, emphasizing the shift from treating ailments to focusing on preventive care for dogs. They explore innovative tests such as metabolic and genetic assessments, as well as the concept of biological age for dogs. Peak canine aims to extend dogs' lifespans and overall well-being through insights and advancements in canine care. Stay tuned for the launch of Peak K9 and a new era of comprehensive dog wellness.
Fatty liver affects about one in four individuals worldwide, yet many remain unaware of its impact. In this video, we delve into the significance of addressing this issue. Fatty liver is closely linked to conditions such as diabetes, heart disease, and obesity. Dr. Sanjeev explains the process of fatty liver development, from fat accumulation to inflammation, fibrosis, and potentially cirrhosis. The liver plays a vital role in detoxifying the body and regulating glucose, making its health paramount. Learn about the risk factors, silent progression, and the importance of regular check-ups to monitor liver enzymes. Discover lifestyle changes, including weight loss, exercise, and potential interventions like medications and vitamin E supplements. While this content aims to educate, always consult a healthcare professional for personalized advice. Support our mission to provide valuable health insights by subscribing, liking, and sharing this episode! Your support fuels our passion to create impactful content. Together, we can tackle vital health topics and make informed decisions for a better future!
Join us as we explore what high blood pressure is, its significance, and why it's important to address. I'm taking the role of the patient this time, discussing my own experiences with high blood pressure. We cover various aspects, such as the two numbers in blood pressure readings, the factors that contribute to high blood pressure, the impacts of stress and lifestyle on blood pressure, and effective ways to manage it through diet, exercise, and even supplements like nitric oxide. We also touch on the different classes of blood pressure medications and why they might be necessary in certain cases. If you're concerned about high blood pressure or interested in optimizing your cardiovascular health, this episode is packed with valuable insights. Don't forget to like, share, and subscribe!
In this episode, discover the intriguing world of longevity and biohacking with Dr. Sanjeev Goel, an expert in anti-aging, to explore the potential of Metformin for extending lifespan. Should we embrace its potential benefits? We address this burning question and discuss Metformin's origin, popularity as a diabetes treatment, and its role in potentially extending lifespan. Discover how this medication, discovered in the 1920s, is now being explored beyond diabetes. We touch on the TAME trial led by Dr. Nir Barzilai, aimed at unraveling Metformin's impact on longevity. Before considering its use, remember that Metformin is a prescription medication, and expert consultation is advised. Join us at peakhuman.ca to stay updated on groundbreaking discoveries. Explore our rewards program for exclusive benefits. Tune in as we continue our quest for peak human well-being!
In this episode, join Dr. Sanjeev Goel in introducing Greg Mckettrick, a compounding pharmacist specializing in sexual dysfunction treatment. Greg delves into the role of nitric oxide in sexual health, its age-related decline, and potential heart issue indicators. Learn about nitric oxide production through L-Arginine and dietary nitrates, with insights on supplement reliability. Discover the importance of oral enzymes, good oral care, and the rapid benefits of nitric oxide supplements like Berkeley Life. Greg advises on intake adjustments, discusses side effects, and spotlights ongoing clinical trials for improved sexual health. Get answers to your questions and explore Greg's expertise with Revelation and Berkeley Life. Be sure to like, share and subscribe!