Podcasts about researchers

Researchers are documenting more and longer-lasting wildfires in northern Alaska and Canada. In fact, the increase of wildfires is a trend across the Arctic, as far as Norway and Siberia, driven by higher temperatures and dryer conditions. The trend has immediate threats to people's homes and health. Some tribes in Alaska and Canada also worry about the possibility of a long-term cataclysmic cycle of fires burning through vast stores of peat, producing uncountable amounts of carbon into the atmosphere. We'll get a look at the latest research and learn what concerned Alaska Native tribes and other Indigenous stakeholders are doing to prepare. GUESTS Edward Alexander (Gwich'in), co-chair for Gwich'in Council International and senior Arctic Lead Woodwell Climate Research Center Dr. Amy Cardinal Christianson (Métis), senior fire advisor for the Indigenous Leadership Initiative and board member of the International Association of Wildland Fire Malinda Chase (Deg Hit'an), tribal liaison for the Alaska Climate Adaptation Science Center under the International Arctic Research Center at the University of Alaska Fairbanks and the land manager for her village Anvik

Marian Montanha, narrates her blog written for the Dementia Researcher website. In this blog, Marian argues that research should be a standard part of every dementia diagnosis. Drawing on her experience across the care pathway, she highlights how many people miss out on opportunities to take part in research because it is not routinely discussed or offered. She calls for a shift in how healthcare professionals frame the dementia journey, ensuring research is seen not as an afterthought but as an essential option that provides hope, purpose, and the chance to contribute to progress for future generations. Find the original text, and narration here on our website. https://www.dementiaresearcher.nihr.ac.uk/blog-including-research-in-every-dementia-diagnosis/ --   Marian Montanha is a Clinical Studies Office in the NHS – Neuroprogressive and Dementia Network in Scotland. With a background in Psychology and a keen interest in Neuropsychology, Marian plays a vital role in clinical research, coordinating and managing clinical trials, ensuring smooth operations, and maintaining accurate records, while also promoting research and collaborating with clinical teams. Passionate about patient care, she is driven to help people maintain dignity, independence, and quality of life. Marian's top tip for ECRs? “You don't know what you don't know”. Find Marian on LinkedIn -- Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk This podcast is brought to you in association with Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support. -- Follow us on Social Media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Join our community: https://onelink.to/dementiaresearcher

Listen to today's podcast... Sometimes when we try to multi-task, we may actually freeze up, lock up, or quit performing at our peak. There is so much pressure to get things done in a day, that we try to split our focus and work on several things at once.  Researchers have studied human multi-tasking for the past 25 years or so and have found that the brain cannot fully focus when multi-tasking. We take longer to complete tasks, often double or more the time, and are predisposed to error.   Take One Action Today To Build Your #Resiliency!      Here Are My Tips For Building Resilience and Celebrating ZeroTasking Day: Today is the day to take it easy, give up multitasking, and try doing nothing. Not for the whole day. But try for an hour. And if that is too long, try 20 minutes. See how you feel and if being anxious was the only thing that you could focus on, know that being able to be still for a moment and quiet your mind and body takes practise. If you weren't successful, try again next weekend. Finally, let go of the idea that the more we tackle at any given time, the more productive we will be. Maintain your productivity by setting your priorities for a focused period of time and don't let distractions take you off course.  If you like today's wellness tips, let me know. You can leave me a review on amazon or through your #alexa app. Don't forget that you can find more tips for coping with mental health issues, by checking out my Live Smart blog at worksmartlivesmart.com #mentalhealth #hr

Taurid Resonance Swarm Alert: A new study highlights the potential threat posed by the Taurid Resonance Swarm, a dense cluster of celestial bodies within an annual meteor shower. Researchers emphasize the need for enhanced monitoring and planetary defense strategies, particularly during key years in 2032 and 2036 for targeted observations.China's Tiangong Space Station Milestone: China successfully launched its 10th crew to the Tiangong Space Station with the Shenzhou 21 mission. This mission features the youngest astronaut sent to space by China and includes 27 scientific experiments, including vital biological research on rodent mammals in microgravity.Blue Origin's New Glenn Rocket Test: Blue Origin completed a significant static fire test of its New Glenn rocket, preparing for its inaugural flight carrying NASA's Escapade mission to Mars. The mission aims to study Mars' magnetosphere and features a humorously named booster, "Never tell me the odds."Radical Mundanity and the Fermi Paradox: A new theory proposes the Radical Mundanity principle as a potential answer to the Fermi paradox. It suggests that technological civilizations may not progress to super-advanced states, leading to quieter, less detectable technosignatures than previously assumed.ESA's Space Safety Initiative: The European Space Agency is expanding its space safety program to address natural and man-made hazards. Key missions include Vigil for solar storm warnings, HERA for asteroid impact studies, and a focus on active debris cleanup with a zero debris approach for future satellites.For more cosmic updates, visit our website at astronomydaily.io. Join our community on social media by searching for #AstroDailyPod on Facebook, X, YouTubeMusic, TikTok, and our new Instagram account! Don't forget to subscribe to the podcast on Apple Podcasts, Spotify, iHeartRadio, or wherever you get your podcasts.Thank you for tuning in. This is Anna and Avery signing off. Until next time, keep looking up and exploring the wonders of our universe.✍️ Episode ReferencesTaurid Resonance Swarm Study[NASA](https://www.nasa.gov/)China's Tiangong Space Station Mission[China National Space Administration](http://www.cnsa.gov.cn/)Blue Origin's New Glenn Rocket Test[Blue Origin](https://www.blueorigin.com/)Radical Mundanity Theory[Nature Astronomy](https://www.nature.com/natastronomy/)ESA's Space Safety Program[European Space Agency](https://www.esa.int/)Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click Here

Welcome to Ozempic Weightloss Unlocked, where we break down the most up-to-date stories in the world of Ozempic, from healthcare breakthroughs to the cultural waves reshaping how we think about weight loss. I am glad you are here.Let us dig into one of the biggest developments making headlines: a national Gallup survey just revealed that the United States is seeing a real decrease in adult obesity rates for the first time in years. This is not just a blip. Experts are linking the trend to the rapid rise in use of GLP-1 medications like Ozempic. According to Healthline and CBS News, the number of Americans using these injectables for weight loss has more than doubled in just the past year, with about twelve percent now reporting current use. Women are leading the charge in use and have seen slightly bigger drops in obesity rates compared to men.The story does not stop with adults. Think Global Health points out that Ozempic and similar drugs are being prescribed more frequently to adolescents, with use in children and teens increasing by nearly six hundred percent over the last five years. This surge follows Food and Drug Administration approval for ages twelve and up, but experts caution that pediatric guidelines and global access remain uneven.Back to the grown-ups: age seems to be a key factor. According to Gallup's analysis, adults between forty and sixty-four years old are using these medications most and have had the greatest reductions in obesity rates. Meanwhile, older Americans show higher rates of using these drugs but do not see as big an impact on their obesity numbers.Now, what is happening in the body when someone takes Ozempic? These medications work by mimicking hormones in the gut that help control appetite. They make you feel full longer, reduce hunger, and even curb cravings for fatty foods. The result is, as Medical News Today explains, many people lose meaningful weight — and maintain improvements in blood sugar, blood pressure, and cholesterol levels.But here is something that might surprise you. According to a large international study led by University College London and shared in Science Daily, Ozempic does not just help with weight. It reduces the risk of heart attack and stroke by about twenty percent, even for people who do not lose a lot of weight while on the drug. Researchers saw these heart benefits for people across a range of body types. The study found that a reduction in waist size did explain some of the improvement in heart health, but a full two-thirds of the benefits seemed unrelated to weight loss alone, which suggests Ozempic may support heart health through other mechanisms.Let us talk long-term results, because listeners want to know what happens after the initial weight loss. New research shared in the Cochrane Database of Systematic Reviews and reported by major health outlets compared Ozempic to other leading medications. Drugs like Mounjaro helped patients lose up to sixteen percent of their body weight over twelve to eighteen months and keep it off for as long as three and a half years. For Ozempic, the sustained weight loss averaged eleven percent over sixteen months, with benefits lasting for around two years. All of these drugs outperformed older medications in long-term trials.However, experts say it is important to be aware of the whole picture. Like all medications, Ozempic and similar drugs come with side effects. The most common are digestive issues like nausea, constipation, or diarrhea, along with headaches and abdominal pain. Fatigue can occur too. And doctors stress that weight management with these drugs is not quick or effortless. It is a long-term process that requires commitment to healthy habits in diet and movement for the results to last.One final thought: as usage spreads, voices like the Pew Research Center note that most Americans now see these medications as a good option for people with true weight-related health issues. Still, a sizeable stigma remains about using them for non-medical reasons.Thank you for tuning in to Ozempic Weightloss Unlocked, where the science and stories making headlines come straight to your headphones. Do not forget to subscribe for all the latest news on Ozempic and its impact on health, lifestyles, and beyond.This has been a quiet please production, for more check out quiet please dot ai. Some great Deals https://amzn.to/49SJ3QsFor more check out http://www.quietplease.aiThis content was created in partnership and with the help of Artificial Intelligence AI

Karin Wilkinson, the talented author behind the “Stolen Seed, Evil Harvest” is an extraordinary individual. Her personal experiences as an alien abductee and survivor have shaped her unique perspective, infusing her writing with a profound sense of authenticity. Karin's groundbreaking research into the phenomenon of alien abductions has allowed her to shed light on a subject often stigmatized or dismissed by mainstream society. With a relentless dedication to uncovering the truth and offering solace to other abductees, Karin Wilkinson has carved a prominent place for herself in the world of literature and paranormal research. Her novels serve as both gripping works of fiction and a source of hope and understanding for those who have encountered similar inexplicable encounters.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-x-zone-radio-tv-show--1078348/support.Please note that all XZBN radio and/or television shows are Copyright © REL-MAR McConnell Meda Company, Niagara, Ontario, Canada – www.rel-mar.com. For more Episodes of this show and all shows produced, broadcasted and syndicated from REL-MAR McConell Media Company and The 'X' Zone Broadcast Network and the 'X' Zone TV Channell, visit www.xzbn.net. For programming, distribution, and syndication inquiries, email programming@xzbn.net.We are proud to announce the we have launched TWATNews.com, launched in August 2025.TWATNews.com is an independent online news platform dedicated to uncovering the truth about Donald Trump and his ongoing influence in politics, business, and society. Unlike mainstream outlets that often sanitize, soften, or ignore stories that challenge Trump and his allies, TWATNews digs deeper to deliver hard-hitting articles, investigative features, and sharp commentary that mainstream media won't touch.These are stories and articles that you will not read anywhere else.Our mission is simple: to expose corruption, lies, and authoritarian tendencies while giving voice to the perspectives and evidence that are often marginalized or buried by corporate-controlled media

In this fascinating episode of Sasquatch Odyssey,  Brian welcomes Justin from Tennessee — Bigfoot researcher, conference speaker, and author of The Epic of Esau: The Birthright and Seed War — for an in-depth discussion on the connections between biblical history, ancient mythology, and modern Bigfoot encounters.Justin shares how his interest in Sasquatch began not in the woods, but in the Bible, where a passage referencing “hairy men” and “wild men of the wilderness” sparked his curiosity.That single verse led him on a journey through scripture, history, and legend, uncovering surprising links between the biblical Nephilim, Amalekites, and the mysterious beings we know today as Bigfoot. The conversation delves deep into Justin's research — from his experiences at the Smoky Mountain Bigfoot Conference to his comparative studies of ancient texts, apocryphal writings, and cross-cultural myths that describe giant or hairy beings with supernatural qualities. Together, Brian and Justin discuss the scientific challenges of studying Bigfoot, the academic resistance to cryptid research, and the divide within the Bigfoot community between those who see Sasquatch as purely physical versus those who believe it may also have spiritual or interdimensional aspects.Justin also discusses his book, The Epic of Esau, which combines biblical interpretation, mythological analysis, and anthropological theory to present a unique framework for understanding Bigfoot's origins — one that could bridge faith, science, and folklore.This episode is a must-listen for anyone intrigued by the possibility that ancient texts and sacred stories may hold forgotten truths about the Sasquatch phenomenon. Whether you lean toward science, spirituality, or both, this thought-provoking discussion will challenge what you thought you knew about Bigfoot — and human history itself. Get Justin's BookGet Our FREE NewsletterGet Brian's Books Leave Us A VoicemailVisit Our WebsiteSupport Our SponsorsBecome a supporter of this podcast: https://www.spreaker.com/podcast/sasquatch-odyssey--4839697/support.

In this episode of SpaceTime, we delve into groundbreaking discoveries that could reshape our understanding of life on Mars and the cosmos beyond.Martian Ice: A Potential Reservoir for LifeA recent study suggests that Martian ice may be the most promising location to search for signs of ancient microbial life. Researchers found that biomolecules from dormant microbes degrade significantly slower in pure water ice compared to Martian soil mixtures. This discovery, published in the journal Astrobiology, raises hopes that future missions to Mars could uncover preserved organic materials in its icy regions, potentially revealing the planet's biological history.A Mysterious Dark Object in the UniverseAstronomers have identified the lowest mass dark object ever detected, with a mass about a million times that of our Sun. This enigmatic object, reported in Nature Astronomy, may offer insights into the nature of dark matter, which constitutes a significant portion of the universe's mass. The object was detected through gravitational lensing, and its small size challenges existing theories about dark matter's composition and distribution.NASA's Call for Lunar Mission BidsNASA is seeking new bids for its Artemis Moon program, aiming to foster competition among American companies to return humans to the lunar surface. With ongoing delays from SpaceX, NASA Administrator Sean Duffy emphasizes the urgency of the mission as the U.S. races against China to achieve lunar exploration milestones. The upcoming Artemis missions promise to be pivotal in establishing a sustainable human presence on the Moon.November Skywatch with Jonathan Nallywww.spacetimewithstuartgary.com✍️ Episode ReferencesAstrobiology Journalhttps://www.liebertpub.com/journals/astrobiology/1Nature Astronomyhttps://www.nature.com/natureastronomy/Become a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.Martian Ice: A Potential Reservoir for LifeA Mysterious Dark Object in the UniverseNASA's Call for Lunar Mission Bids

Dr. John Neustadt is a Doctor, Author, Researcher, and integrative medical expert. He's an expert on Bone Strength, fracture prevention, and reversing osteoporosis. Many of us could benefit from the books he has written about bone strength, including "Fracture Proof Your Bones: A comprehensive Guide to Osteoporosis" Available HERE: https://amzn.to/433J422RESOURCES:Buy the book "Fracture Proof Your Bones: A comprehensive Guide to Osteoporosis"https://amzn.to/433J422This Episode's Blog Page:https://drhaley.com/reversing-osteoporosis/Dr. Neustadt's Website Supplement Website:https://www.nbihealth.com/Dr. Neustadt on Social Media:X: https://twitter.com/JohnNeustadt/LinkedIn: https://www.linkedin.com/in/john-neustadt-nd-1553576/Facebook: https://www.facebook.com/nbihealth/YouTube: @NBIHealth Dr. Neustadt's Podcast on iTunes:https://podcasts.apple.com/us/podcast/delivering-health/id1504980399This episode on YouTube:https://www.youtube.com/watch?v=h2rNlHaa9zQTIMESTAMPS:00:00 Intro Snip00:59 Introduce Dr. John Neustadt from NBI Health02:04 The story of Mary who broke her hip and died a few days later05:35 How long do women live after breaking a hip and how often does someone break a bone because of osteoporosis?06:47 What is the bone density test and what is lacking fracture risk prediction?08:40 What other tests can screen for bone strength?10:31 when people get to the point of vertebrae collapsing, can they turn it around and restrengthen those bones?11:50 What is the most common timing of bone loss and osteoporosis?13:00 What are the medications that contribute to osteoporosis?15:55 What is the difference between how medicine treats osteoporosis vs. how naturally we treat osteoporosis?21:25 What are the natural things to do to reverse osteoporosis?25:50 what four nutrients have been shown in clinical trials to prevent fractures?27:46 What is the safe levels of daily calcium intake?32:50 What is the difference between Vitamin MK7 and MK4?36:00 Why did you create your brand of supplements?38:00 What form of vitamin K is in the foods and what will I find in the health food stores?40:10 What are the best food sources of protein and the k vitamins, and nutrients that prevent fractures?44:12 Where do we find your supplements and which are your most popular? NBIHealth.com48:07 What are your favorite exercises to prevent fractures?

Dr. Arun Sharma Monday 10-27-25 Space ShowQuick Summary:Our program focused on the establishment and operations of Cedars-Sinai's new Space Medicine Research Center, including its research programs, educational components, and institutional support. Arun discussed their stem cell research initiatives, particularly the creation of 3D heart tissue organoids grown in microgravity on the ISS, and explained their approach to training astronauts and conducting space-based medical research. The conversation covered the potential of AI and telemedicine in space missions, regulatory challenges in stem cell research, and the future opportunities presented by commercial space stations for conducting biomedical research. David and Arun were joined by participant Dr. Sherry Bell.Detailed Summary:David and Dr. Sherry Bell discussed the establishment of the Center for Space Medicine Research at Cedars-Sinai, led by Arun. Arun confirmed the center's functionality and its institutional support, emphasizing its research and educational components. After Arun was welcomed back to The Space Show to discuss Cedars-Sinai Medical Center's new Space Medicine Research Center. Arun explained that the center, established about a year ago, builds on their 10 years of work in stem cell and biomanufacturing research, including 8 missions to the ISS. He noted that the center has both research and educational components, offering courses in space medicine and biosciences as part of their master's and PhD programs. Arun emphasized their institutional support and goal to become an academic partner for the growing private space industry in Los Angeles.Arun discussed Cedars' expansion beyond cardiovascular focus to broader biomanufacturing and space research, with plans to establish a clinical arm leveraging their hospital's expertise. He mentioned ongoing conversations with local space industry players in LA, though details are not yet public. Arun also outlined their vision for a comprehensive space medicine program, including pre-flight workups, in-flight diagnostics, and post-flight checkups, while acknowledging the need for space medical training for their network of providers.Arun further discussed his research on 3D heart tissue, or cardiac organoids, created from induced pluripotent stem cells (iPSCs). He explained that these tissues are grown in microgravity on the ISS, as microgravity may improve their growth compared to simulated microgravity on Earth. Arun clarified that the iPSCs and necessary chemicals were launched on SpaceX 33 in August and are now orbiting Earth. David inquired about astronaut training, and Arun explained that they work with engineers and partners like BioServe Space Technologies to train astronauts, as most are not life scientists. Arun expressed a desire for more direct communication with astronauts in the future.The discussion then focused on stem cell research and space medicine training. Arun explained that stem cells are sourced from de-identified donor samples at Cedars-Sinai, with consent for medical research use. The long-term goal is to create patient-specific bioengineered organs, starting with heart tissues, though this remains an area of ongoing research. Arun clarified that the initial training program will focus on biosciences for research scientists, with plans to expand to clinical training in the future.Arun did talk about the potential of AI and telemedicine in supporting deep space missions, emphasizing the value of human-focused research over animal studies. He clarified that his lab uses patient-specific stem cell models, focusing on human biology, and does not work with embryonic stem cells. Arun also addressed the cost and funding challenges of conducting research in space, mentioning partnerships with government agencies and the need to explore alternative funding sources for future collaborations. David inquired about simulating microgravity studies, to which Arun explained that while some ground-based simulations exist, they do not perfectly replicate the conditions of true space microgravity.Arun explained that the stem cell research at Cedars Space Lab involves creating three-dimensional organoids to study human biology and potentially identify new drugs, but emphasized that these cells cannot be transplanted back into people due to ethical and regulatory constraints. He clarified that the research is outcome-oriented, focusing on whether stem cells can be improved in space, with the goal of creating better models for understanding heart development and drug efficacy. David raised concerns about potential regulatory differences between countries, particularly regarding stem cell research, and Arun acknowledged that while the US has strict guidelines, some international research may go unpublished, making it difficult to track all ongoing work in this field.Arun discussed his work as a stem cell biologist and highlighted the potential of space biology research, mentioning a recent publication by UC San Diego on growing cancer cells in space. He expressed concerns about the transition from the ISS to commercial space stations, acknowledging the ISS's valuable contributions to research but seeing an opportunity for the commercial industry to fill the gap. Arun also considered the possibility of conducting research on a commercial space station, emphasizing the potential for more biomedical researchers in space and the possibility of accelerated training in a private space capacity. He expressed interest in the idea of conducting his own research on a private space station, such as SpaceX's Starship, and noted the importance of access and opportunities for further research.Arun discussed the differences between microgravity and partial gravity environments in space, highlighting the potential for developing unique therapeutic options that may only be applicable in space. He explained that while some treatments could be brought back to Earth, others might require patients to travel to space for treatment. Arun also touched on the current state of stem cell research, including clinical trials for various applications, and expressed optimism about future advancements in bioprinting and organoid manufacturing in space. He emphasized the importance of personalized medicine using patient-specific stem cells and encouraged continued interest in both stem cell and space biology research.Be sure to see the video of this program at doctorspace.substack.com.Special thanks to our sponsors:Northrup Grumman, American Institute of Aeronautics and Astronautics, Helix Space in Luxembourg, Celestis Memorial Spaceflights, Astrox Corporation, Dr. Haym Benaroya of Rutgers University, The Space Settlement Progress Blog by John Jossy, The Atlantis Project, and Artless EntertainmentOur Toll Free Line for Live Broadcasts: 1-866-687-7223 (Not in service at this time)For real time program participation, email Dr. Space at: drspace@thespaceshow.com for instructions and access.The Space Show is a non-profit 501C3 through its parent, One Giant Leap Foundation, Inc. To donate via Pay Pal, use:To donate with Zelle, use the email address: david@onegiantleapfoundation.org.If you prefer donating with a check, please make the check payable to One Giant Leap Foundation and mail to:One Giant Leap Foundation, 11035 Lavender Hill Drive Ste. 160-306 Las Vegas, NV 89135Upcoming Programs:Broadcast 4455 ZOOM: Arkisys CEO David Barnhart | Sunday 02 Nov 2025 1200PM PTGuests:ZOOM, Dave Barnhart, CEO of Arkisys updates us with interesting news and developments Get full access to The Space Show-One Giant Leap Foundation at doctorspace.substack.com/subscribe

Episode 329 America's health data system is in crisis. The US government has been bleeding public health experts – many of whom run crucial public health surveys and databases which help identify, monitor and respond to health threats across the country. From drug use to food security and birth data, discover the 5 surveys most critically hit by the axing of over 20,000 jobs. If nothing is done to address this, vital health information will be missed and the results could be catastrophic. Do you find it difficult to concentrate after a bad night's sleep? This might be really common, but scientists are still trying to figure out why it happens. A new finding suggests it might have something to do with the brain's “rinse cycle” – a process where your brain washes away metabolic waste and toxic proteins. Although this usually happens while you sleep, researchers have discovered it may continue in the day if you're sleep deprived. Life might exist on Mars right now, thanks to a network of liquid water on the Red Planet. Researchers examining Mars' soil say there's a good chance tiny veins of liquid water are hiding under the Martian permafrost and that they could support microbial life. This finding has scientists excited, with one suggesting “it's not impossible that life could exist in the Martian near surface.” Chapters: (00:00) Intro (01:00) The collapse of America's health data system (08:00) How sleep affects your focus (16:40) Best place to search for life on Mars Hosted by Penny Sarchet and Timothy Revell, with guests Grace Wade, Carissa Wong and Leah Crane. To read more about these stories, visit https://www.newscientist.com/ Check out Carissa's story on the lymphatic system here: https://www.newscientist.com/article/2499831-the-extraordinary-influence-of-the-lymphatic-system-on-our-health/  Find Wellcome's podcast here: https://wellcome.org/insights/podcast  Learn more about your ad choices. Visit megaphone.fm/adchoices

Grandma Hobbies to Try This Winter:CrochetingCompleting a coloring bookKnittingPuzzlingBakingScrapbookingPlaying a board gameJewelry makingNeedlepointingEmbroideringMost Americans Spend a Third of Their Paycheck within 12 hours: Feel like your paycheck is gone as soon as you get it? Researchers find that's pretty much true for a lot of us. According to new research, the average American spends more than a third of their paycheck within the first 12 hours of receiving it.  What's Trending: Bay Area restaurants are coming together to support families affected by the SNAP benefit suspension, offering free or discounted meals to help ensure no one goes hungry, starting November 1st.  San Francisco:The Rusty LadleAl Pastor PapiOakland:Monster PhoUnderstoryPuerto Rican Street CuisineSan Jose:Toni and Alba's PizzaShrimp'n Ain't Easy(Food Truck)Santa Clara:Gamers HeavenConcord/Antioch:OG TacosSecond Date Update: Josh thought his tapas date with Tamara was a hit—great food, flirty banter, and zero awkward silences. They agreed: team books, not screens. He left confident. She left… and never texted back  The Most Successful Marriage Proposals Happen at Home: What were the other somewhat successful places?Outdoors (18.4%)Beach (12.4%)Restaurant (5.6%)Mountains (3.9%)Good News: Meet Poppy, 10, from Holborough Lakes. Diagnosed with dyslexia, she calls it her ‘superpower'—and with an IQ of 136, she just joined Mensa! Poppy hopes her story will show that thinking differently is a gift, not a limitation.

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Using High-Tech To Find Homes Adi Pinhas is using facial recognition technology in his new iPhone app. You'll upload a picture of the pet you want, and it'll tell you all the adoptable animals that look like the original picture. The Verge Magazine uploaded a picture of Lady Gaga and got back an adoptable hamster. Listen Now Pets In The Classroom New research says kids learn better when their classroom has a pet. Even truancy is down. We all remember the class pet. And if you were lucky, the teacher let you take the guinea pigs home for the summer. Brent Weinmann of the Pet Care Trust is making sure all kids get an opportunity to have pets in their classroom. Listen Now Cure For Parvo? Researchers may have literally stumbled on a way to treat the usually fatal Parvo virus. It happened when a pharmaceutical was looking for a way to save flocks of geese that were mysteriously dying. They discovered an antibody that's harvested from the yokes of goose eggs that can stop the Parvo virus in as little as two days. Listen Now Calf Gets Prosthetic Back Legs Kitty Martin loves her calf so much that she's put more than $40,000 into rescuing the steer after its back legs were amputated because of frostbite. She's the Hero Person this week with a great story to tell about the human-bovine connection. Listen Now Sharing Your Bed With Your Pet Leads to Bad Sleep Quality If you have a cat or dog, chances are they sleep with you in bed. But new research says that sharing your bed with your pet can lead to bad sleep quality. Recently, at the annual meeting of the Associated Professional Sleep Societies, data was presented that showed at least 30% of pet owners say their pets wake them up at least once per night. Listen Now Read more about this week's show.

About a quarter of Delaware youth identify as LGBTQ+, according to the Delaware School Survey.And a new study from the University of Delaware finds LGBTQ+ adolescents experience higher rates of anxiety, depression and substance use.They're also more likely to report all three at younger ages than their cisgender, heterosexual counterparts.Delaware Public Media's Abigail Lee recently sat down with UD assistant professor of Human Development and Family Sciences Eric Layland to talk about his study's findings and what they mean for the First State.

Here are 3 big things you need to know—   One — The government shutdown is entering entered its 30th day with no end in sight.  A 13th effort to end the shutdown impasse failed in the Senate and there are no plans to vote on the measure today.  The Trump administration says that the military will be paid, but thousands of air traffic controllers have missed their first full paycheck.    Two ---  The Federal Reserve is cutting interest rates for a second straight meeting.  The Fed lowered interest rates by a quarter percentage point today.  The benchmark rate is now in a range of three-point-75-percent to four-percent.   And number three ---    A new study is suggesting women may need less exercise than men to have a healthy heart.  Researchers in the UK found women who got around four hours of moderate exercise each week lowered their risk of heart disease by about 30 percent.  It found men, however, needed about eight hours of exercise per week to achieve the same level of heart health. 

Flying mammals of the night have been under threat of white-nose syndrome in the U.S. for years. Oklahoma researchers are tracking their populations and finding positive results.Mentioned in this episode:Social Media tags

In this episode, I connect with Peter Bird, a resident of Heidelberg, Germany, and a doctoral researcher at the Technical University (TU) Eindhoven in the Netherlands, to continue my discussions* about the Cycling Cities Initiative. He is studying and documenting the historical context of Minneapolis as an impressive North American example of a Cycling City. *ICYMI: Refer to Episode 311 feat. Prof. Ruth OldenzielHelpful Links (note that some may include affiliate links to help me support the channel):

VortexNet uses actual whirlpools to build neural networks. Seriously. By borrowing equations from fluid dynamics, this new architecture might solve deep learning's toughest problems—from vanishing gradients to long-range dependencies. Today we explain how vortex shedding, the Strouhal number, and turbulent flows might change everything in AI.   Sponsors This episode is brought to you by Statistical Horizons  At Statistical Horizons, you can stay ahead with expert-led livestream seminars that make data analytics and AI methods practical and accessible. Join thousands of researchers and professionals who've advanced their careers with Statistical Horizons. Get $200 off any seminar with code DATA25 at https://statisticalhorizons.com     References https://samim.io/p/2025-01-18-vortextnet/  

Today's headlines include: The NSW Government is seeking urgent action to stop thousands of prison guards across the state from walking off the job. U.S. President Donald Trump and Chinese President Xi Jinping have struck a deal to reduce tariffs, after meeting for the first time since 2019. A drug raid in the Brazilian city of Rio de Janeiro has left at least 132 people dead, marking the deadliest police operation in the country’s history. And today’s good news: Researchers have discovered an antibiotic that’s 100 times stronger than existing ones, and is effective against deadly superbugs. Hosts: Emma Gillespie and Lucy TassellProducer: Emma Gillespie Want to support The Daily Aus? That's so kind! The best way to do that is to click ‘follow’ on Spotify or Apple and to leave us a five-star review. We would be so grateful. The Daily Aus is a media company focused on delivering accessible and digestible news to young people. We are completely independent. Want more from TDA?Subscribe to The Daily Aus newsletterSubscribe to The Daily Aus’ YouTube Channel Have feedback for us?We’re always looking for new ways to improve what we do. If you’ve got feedback, we’re all ears. Tell us here.See omnystudio.com/listener for privacy information.

There is a lot of discussion about the validity of science right now.Researchers talk endlessly about how to make results “more valid,” how to fix problems, and how to improve the system.But here is what I actually think.It is not about “bad apples.”It is almost never about that.The real issue is culture.And culture often comes down to one or two people inside a community who stress performance above all else. Those one or two people create tension. They make others feel lesser than. They make you feel like you are the problem. And then everything starts to bend around that pressure.This is true everywhere.Every organization. Every department. Every field.You can feel it when the conversation becomes only about outcomes:number of citations, number of papers, number of grants.All lagging indicators. All terrible predictors.My field in strategy does this constantly.It is completely wrong.And it has been wrong for a long time.A lot of this came from the old Jack-Welch-style management thinking of the 1980s. That mindset seeped everywhere. It made people believe outcomes were all that mattered. Just hit the number. Hit the target. Hit the metric.But if you look at the research coming out of the systems-dynamics world at MIT — the Sterman group especially — the story is always the same:When you focus on outcomes, everything erodes.Eventually it all falls apart.Because outcomes are not the thing that matters.What matters is whether people feel safe.What matters is whether people feel supported.What matters is whether there is unconditional kindness in the room instead of fear.You fix culture, you fix science.And none of that starts with performance.

Researchers figure livestock herds contribute between 12% and 20% of the world's greenhouse gas emissions. That's mostly methane from the digestive process. But a study from UC Davis finds that, when fed seaweed early on, cattle's microbiome can be altered, reducing the amount of methane emissions. But first, the Federal Reserve is expected to cut interest rates by a quarter of a percentage point — though they have limited data to go off of.

Researchers figure livestock herds contribute between 12% and 20% of the world's greenhouse gas emissions. That's mostly methane from the digestive process. But a study from UC Davis finds that, when fed seaweed early on, cattle's microbiome can be altered, reducing the amount of methane emissions. But first, the Federal Reserve is expected to cut interest rates by a quarter of a percentage point — though they have limited data to go off of.

A poll from the journal Nature found that 75% of researchers in the U.S. are considering leaving the country. That includes a man who’s been dubbed the "Mozart of Math." Stephanie Sy examines what’s behind a potential scientific brain drain. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

(00:00:00) Lunar Relics and Interstellar Insights: Discoveries from the Moon and Comet 3I ATLAS (00:00:46) Relics of the outer solar system discovered on the Moon (00:03:30) Insights from interstellar comet 3I ATLAS (00:07:31) SpaceX's Starship Mega rocket test flight (00:23:54) The Science report (00:31:46) Episode Wrap In this episode of SpaceTime, we explore remarkable discoveries that provide new insights into our solar system and beyond.Relics of the Outer Solar System Found on the MoonA groundbreaking study reveals that meteorites found on the Moon originated from the outer solar system. Researchers from the Chinese Academy of Sciences have identified olivine-bearing clasts from lunar regolith collected by the Chang'e 6 mission. These relics, believed to be carbonaceous chondrites, offer critical information about the formation and evolution of planets. The findings suggest that the Moon serves as a pristine archive for meteorites, with implications for understanding the origins of lunar water and organic materials.Interstellar Comet 3I ATLAS: Insights into Alien Solar SystemsThe interstellar comet 3I ATLAS is revealing fascinating details about the composition of other solar systems. New observations indicate that 3I ATLAS has been active longer than expected, releasing various molecules as it travels through our solar system. This segment discusses how the comet's behavior challenges existing assumptions about comet activity and provides clues about the materials present in distant star systems.SpaceX's Starship Mega Rocket Test FlightSpaceX has successfully completed its 11th test flight of the Starship Mega rocket, demonstrating significant advancements in its design and capabilities. The mission involved various maneuvers, including hot staging and payload deployment, as well as tests of the spacecraft's reentry and landing procedures. This episode highlights the importance of these tests for future missions to the Moon and Mars, as SpaceX continues to refine the Starship for interplanetary travel.www.spacetimewithstuartgary.com✍️ Episode ReferencesProceedings of the National Academy of Scienceshttps://www.pnas.org/Astrophysical Journal Lettershttps://iopscience.iop.org/journal/2041-8205Become a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.Relics of the Outer Solar System Found on the MoonInterstellar Comet 3I ATLAS: Insights into Alien Solar SystemsSpaceX's Starship Mega Rocket Test Flight

Iain Thomas is a poet, author, and the Chief Innovation Officer at Sounds Fun—an advertising and creative agency that he co-founded with the belief that human creativity could be enhanced, rather than diminished, with the help of AI. It's a realization that actually began to dawn on Iain a few years prior, after his mother died. He wasn't sure how to explain death to his children, so he turned to an early version of ChatGPT for help—and was so impressed by the poetry of its responses that he came away convinced of AI's immense potential as a thought partner for his creative work. On this episode, Iain talks about using AI to make more space for the creative parts of your work, and why, in a world where everyone has access to the same tools, it's never been more important to lean into the skills, context, and experiences that make each of us most unique—and most human.Learn more about Sounds Fun soundsfun.co~ ~ ~Working Smarter is brought to you by Dropbox Dash—the AI universal search and knowledge management tool from Dropbox. Learn more at workingsmarter.ai/dashYou can listen to more episodes of Working Smarter on Apple Podcasts, Spotify, YouTube Music, Amazon Music, or wherever you get your podcasts. To read more stories and past interviews, visit workingsmarter.aiThis show would not be possible without the talented team at Cosmic Standard: producer Dominic Girard, sound engineer Aja Simpson, technical director Jacob Winik, and executive producer Eliza Smith. Special thanks to our illustrators Justin Tran and Fanny Luor, marketing consultant Meggan Ellingboe, and editorial support from Catie Keck. Our theme song was composed by Doug Stuart. Working Smarter is hosted by Matthew Braga. Thanks for listening!

Researcher and trainer Hardy Merriman: After ‘No Kings Day' Protests, New Strategies & Tactics Needed to Resist Trump's Authoritarian AgendaYale School of Public Health associate professor Gregg Gonsalves: Defend Public Health Organizes Opposition to Trump-RFK Jr.'s Destruction of US Public HealthTask Force on the Americas' member David Paul: Trump Deploys U.S. Aircraft Carrier Strike Group to Caribbean in Preparation for Possible Venezuela AttackBob Nixon's Under-reported News Summary• Sudanese army fails as rebel paramilitary RSF captures western city of el-Fasher• Kurdish cousins' political party rivalry erupting into Iraqi Kurdistan civil war• Human rights organization's Fair Food Program fights to provide ethically-sourced cropsVisit our website at BTLonline.org for more information, in-depth interviews, related links, transcripts and subscribe to our BTL Weekly Summary and/or podcasts. New episodes every Wednesday at 12 noon ET, website updated Wednesdays after 4 p.m. ETProduced by Squeaky Wheel Productions: Scott Harris, Melinda Tuhus, Bob Nixon, Anna Manzo, Susan Bramhall, Jeff Yates and Mary Hunt. Theme music by Richard Hill and Mikata.

Researcher and trainer Hardy Merriman: After ‘No Kings Day' Protests, New Strategies & Tactics Needed to Resist Trump's Authoritarian AgendaYale School of Public Health associate professor Gregg Gonsalves: Defend Public Health Organizes Opposition to Trump-RFK Jr.'s Destruction of US Public HealthTask Force on the Americas' member David Paul: Trump Deploys U.S. Aircraft Carrier Strike Group to Caribbean in Preparation for Possible Venezuela AttackBob Nixon's Under-reported News Summary• Sudanese army fails as rebel paramilitary RSF captures western city of el-Fasher• Kurdish cousins' political party rivalry erupting into Iraqi Kurdistan civil war• Human rights organization's Fair Food Program fights to provide ethically-sourced cropsVisit our website at BTLonline.org for more information, in-depth interviews, related links, transcripts and subscribe to our BTL Weekly Summary and/or podcasts. New episodes every Wednesday at 12 noon ET, website updated Wednesdays after 4 p.m. ETProduced by Squeaky Wheel Productions: Scott Harris, Melinda Tuhus, Bob Nixon, Anna Manzo, Susan Bramhall, Jeff Yates and Mary Hunt. Theme music by Richard Hill and Mikata.

Are you your harshest critic? Dr. Kristin Neff shows how self-compassion is the key to resilience, growth, and high performance. Discover research-backed techniques—mindful awareness, compassionate self-talk, and supportive touch—that help you reduce stress, prevent burnout, and turn setbacks into opportunities. By treating yourself with the same kindness you give others, you can boost focus, emotional strength, and long-term success.Read her book “Mindful Self-Compassion for Burnout” to discover science-backed strategies for resilience, emotional balance, and sustainable success that will help you reduce stress, prevent burnout, and thrive even under pressure.

A poll from the journal Nature found that 75% of researchers in the U.S. are considering leaving the country. That includes a man who’s been dubbed the "Mozart of Math." Stephanie Sy examines what’s behind a potential scientific brain drain. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

This episode is sponsored by Airia. Get started today at ⁠⁠⁠⁠⁠⁠⁠⁠⁠airia.com⁠⁠⁠⁠⁠⁠⁠⁠⁠. On this episode, Jeff and I break down OpenAI's restructuring for profit, look at Qualcomm's new AI200 chips, discuss why Amazon's office job reductions might not be entirely about AI, and share Adobe's latest generative Firefly 5 updates from Adobe Max 2025. Note: Time codes subject to change depending on dynamic ad insertion by the distributor. CHAPTERS: 00:00 Podcast begins 07:24 - OpenAI completes its for-profit recapitalization 16:03 - Amazon to Cut 14,000 Jobs as Jassy Looks to Ease Bureaucracy 18:01 - Nate B Jones on why they really laid off staff 23:38 - Nate B Jones on why they really laid off staff 25:33 - Adobe Now Lets You Generate Soundtracks and Speech in Firefly 33:17 - Researchers exploit OpenAI's Atlas by disguising prompts as URLs 40:15 - Amazon unveils AI smart glasses for its delivery drivers 42:03 - Introducing Blue Jay and Project Eluna, Amazon's latest robotics and AI technology for its operations 45:36 - Elon Musk launches a Wikipedia rival that extols his own ‘vision' 49:25 - Leo's entry says he's semi-retired; news to him, I'll bet 51:58 - Qualcomm Launches AI Chips to Challenge Nvidia's Dominance 52:40 - Nvidia becomes world's first $5tn company 57:28 - Sora update to bring AI videos of your pets, new social features, and soon, an Android version 01:00:48 - Google and Anthropic announce cloud deal worth tens of billions of dollars 01:02:20: Find out what's new in the Gemini app in October's Gemini Drop. Learn more about your ad choices. Visit megaphone.fm/adchoices

Light Samus! Dark Samus! Luminoth sympathizer Max Roberts and Ing supporter Logan Moore split a planet in half just to see if Metroid Prime 2: Echoes could follow-up Retro Studios smash hit. Are two worlds better than one or were ambitions squashed like a bug? Metroid Prime 2: Echoes Developer – Retro Studios Platform – Nintendo GameCube and Wii Release Date – November 15, 2004 Metroid Prime Trilogy - August 24, 2009 Game Director – Mark Pacini Producers – Bryan Walker, Kenji Miki, and Kensuke Tanabe Composer – Kenji Yamamoto Metacritic – 92/100 Links Metroid Prime 2: Echoes Wikipedia PrimeHack Ikaruga Losing to the Boost Guardian a Whole Bunch Dark Samus Kingdom Hearts 2 Final Mix Secret Ending Metroid Prime 2: Echoes 100% Ending Soundtrack YouTube This episode was originally recorded on October 25, 2024. Logan Moore - Comicbook.com Max Frequency - Max's home online The Max Frequency Podcast - Join Max Roberts and guests to talk about video games, creativity, and life. This is podcasting at Max's frequency. Researcher, Editor, and Producer – Max Roberts Hosted by Logan Moore & Max Roberts Art designed by Max Roberts

Joshua Lisbon–a researcher/educator/storyteller at the center of a new PBS/Nature documentary, “Willow: Diary of a Mountain Lion”—describes his background and experience (and academic training) before working on the 10-year study that formed the core content of this doc.Tongue partly in cheek, Lisbon tried to dismiss his education-heavy history as “wrong” for this project. But given […] The post Joshua Lisbon, researcher/educator/storyteller central to “Willow: Diary of a Mountain Lion” first appeared on Talking Animals.

Netflix viewers will be able to vote while watching live content to directly influence the outcome of what they're watching on their TV or mobile device. Also, OpenAI says its deep learning systems are rapidly advancing, with models increasingly able to solve complex tasks faster. So fast, in fact, that internally, OpenAI is tracking towards achieving an intern-level research assistant by September 2026, and a fully automated “legitimate AI researcher” by 2028, CEO Sam Altman said during a livestream Tuesday. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Dr. Andrew Lee, Vice President, Clinical Research at Uniquity Bio, about Thymic Stromal Lymphopoietin (TSLP) and eosinophilic esophagitis (EOE). Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:49] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:13] Holly introduces today's topic, Thymic Stromal Lymphopoietin (TSLP) and eosinophilic esophagitis (EOE), and today's guest, Dr. Andrew Lee, Vice President, Clinical Research at Uniquity Bio.   [1:36] Dr. Lee has nearly 20 years of experience in the clinical development of new vaccines, biologics, and drugs. Holly welcomes Dr. Lee.   [1:52] Dr. Lee trained in internal medicine and infectious diseases.   [1:58] Dr. Lee has been fascinated by the immune system and how it can protect people against infections, what happens when immunity is damaged, as in HIV and AIDS, and how to apply that knowledge to boost immunity with vaccines to prevent infections.   [2:16] Dr. Lee led the clinical development for a pediatric combination vaccine for infants and toddlers. It is approved in the U.S. and the EU.   [2:29] Dr. Lee led the Phase 3 Program for a monoclonal antibody to prevent RSV, a serious infection in infants. That antibody was approved in June 2025 for use in the U.S.   [2:44] In his current company, Dr. Lee leads research into approaches to counteract an overactive immune system. They're looking at anti-inflammatory approaches to diseases like asthma, EoE, and COPD.   [2:58] Dr. Lee directs the ongoing Phase 2 studies that they are running in those areas.   [3:28] Dr. Lee sees drug development as a chance to apply cutting-edge research to benefit people. He trained at Bellevue Hospital in New York City in the 1990s.   [3:40] When Dr. Lee started as an intern, there were dedicated ICU wards for AIDS patients because many of the sickest patients were dying of AIDS and its complications.    [3:52] Before the end of Dr. Lee's residency, they shut down those wards because the patients were on anti-retroviral medications and were doing so well that they were treated as outpatients. They didn't need dedicated ICUs for AIDS patients anymore.   [4:09] For Dr. Lee, that was a powerful example of how pharmaceutical research and drug regimen can impact patients' lives for the better by following the science. That's what drove Dr. Lee to go in the direction of research.   [4:48] Dr. Lee explains Thymic Stromal Lymphopoietin (TSLP). TSLP serves as an alarm signal for Type 2 or TH2 inflammation, a branch of the immune responses responsible for allergic responses and also immunity against parasites.   [5:17] When the cells that line the GI tract and the cells that line the airways in our lungs receive an insult or an injury, they get a danger signal, then they make TSLP.   [5:28] This signal activates other immune cells, like eosinophils and dendritic cells, which make other inflammatory signals or cytokines like IL-4, IL-13, and IL-5.   [5:47] That cascade leads to inflammation, which is designed to protect the body in response to the danger signal, but in some diseases, when there's continued exposure to allergens or irritants, that inflammation goes from being protective to being harmful.   [6:15] That continued inflammation, over the years, can lead to things like the thickened esophagus with EoE, or lungs that are less pliant and less able to expand, in respiratory diseases.   [6:48] Dr. Lee says he thinks of TSLP as being a master switch for this branch of immune responses. If you turn on TSLP, that turns on a lot of steps that lead to generating an allergic type of response.   [7:06] It's also the same type of immune response that can fight off parasite infections. It's the first step in a cascade of other steps generating that type of immune response.   [7:30] Dr. Lee says people have natural genetic variation in the genes that incur TSLP.   [7:38] Observational studies have found that some people with genetic variations that lead to higher levels of TSLP in their bodies had an increased risk for allergic inflammatory diseases like EoE, atopic dermatitis, and asthma.   [8:13] Studies like the one just mentioned point to TSLP being important for increased risk of developing atopic types of diseases like EoE and others. There's been some work done in the laboratory that shows that TSLP is important for activating eosinophils.    [8:38] There's accumulating evidence that TSLP activation leads to eosinophil activation, other immune cells, or white blood cells getting activated.   [9:07] Like a cascade, those cells turn on T-cells and B-cells, which are like vector cells. They lead to direct responses to fight off infections, in case that's the signal that leads to the turning on TSLP.   [9:48] Ryan refers to a paper published in the American Journal of Gastroenterology exploring the role of TSLP in an experimental mouse model of eosinophilic esophagitis. Ryan asks what the researchers were aiming to find.   [10:00] Dr. Lee says the researchers were looking at the genetic studies we talked about, the observational studies that are beginning to link more TSLP with more risk for EoE and those types of diseases.   [10:12] The other type of evidence that's accumulating is from in vitro (in glass) experiments or test tube experiments, where you take a couple of cells that you think are relevant to what's going on.   [10:28] For example, you could get some esophageal cells and a couple of immune cells, and put TSLP into the mix, and you see that TSLP leads to activation of those immune cells and that leads to some effects on the esophageal cells.   [10:42] Those are nice studies, but they're very simplified compared to what you can do in the body. These researchers were interested in extending those initial observations from other studies, but working in the more realistic situation of a mouse model.   [11:00] You have the whole body of the mouse being involved. You can explore what TSLP is doing and model a disease that closely mimics what's happening with EoE in humans.   [12:23] They recreated the situation of what seems to be happening in EoE in people. We haven't identified it specifically, but there's some sort of food allergen in patients with EoE that the immune system is set off by.   [12:55] What researchers are observing in this paper is that in these mice that were treated with oxazolone, there is inflammation in the esophagus, an increase in TSLP levels, and eosinophils going into the esophageal tissues.   [13:15] Dr. Lee says, that's one of the main ways we diagnose EoE; we take a biopsy of the esophagus and count how many eosinophils there are. Researchers saw similar findings. The eosinophil count in the esophageal tissues went way up in these mice.    [13:34] Researchers also saw other findings in these mice that are very similar to EoE in humans, such as the esophageal cells lining the esophagus proliferating. They even saw that new blood vessels were being created in that tissue that's getting inflamed.   [14:00] Dr. Lee thinks it's a very nice paper because it shows that correlation: Increase TSLP and you see these eosinophils going to the esophagus, and these changes that are very reminiscent of what we see in people with EoE.   [14:51] In this paper, the mice made the TSLP, and researchers were able to measure the TSLP in the esophageal tissue. The researchers didn't introduce TSLP into the mice. The mice made the TSLP in response to being repeatedly exposed to oxazolone.   [15:20] That's key to the importance of the laboratory work. The fact that the TSLP is made by the mice is important. It makes it a very realistic model for what we're seeing in people.   [15:41] In science, we like to see correlation. The researchers showed a nice correlation.   [15:46] When TSLP went up in these mice, and the mice were making more TSLP on their own, at the same time, they saw all these changes in the esophagus that look a lot like what EoE looks like in people.    [16:01] They saw the eosinophils coming into the esophagus. They saw the inflammation go up in the esophagus. What Dr. Lee liked about this paper is that they continued the story.   [16:15] The researchers took something that decreases TSLP levels, an antibody that binds to and blocks TSLP, and when they did that, they saw the TSLP levels come down to half the peak level.   [16:35] Then they saw improvement in the inflammation in the esophagus. They saw that the amount of eosinophils decreased, and the multiplication of the esophageal cells went down. The number of new blood vessels went down after the TSLP was reduced.   [16:53] Dr. Lee says, you see correlation. The second part is evidence for causation. When you take TSLP away, things get better. That gives us a lot of confidence that this is a real finding. It's not just observational. There is causation evidence here.   [18:26] Ryan asks if cutting TSLP also help reduce other immune response cells. Dr. Lee says TSLP is the master regulator for this Type 2 inflammation. It definitely touches and influences other cells besides eosinophils.   [18:44] TSLP affects dendritic cells, which are an important type of immune cell, like a coordinating cell that instructs other cells within the immune system what to do. In this paper, they looked at a lot of other effects of TSLP on the tissues of the body.   [19:10] Dr. Lee says, There's a lot of research on TSLP, and one of the reasons we're excited about the promise of TSLP is that it's so far upstream; so much of the beginning, that it's affecting other cells.   [19:29] Its effects could be quite broad. If we're able to successfully block TSLP, we could block a lot of different effects.   [19:40] One treatment for EoE is dupilumab, which blocks IL-4 and IL-13 specifically, and that works well, but TSLP has the potential to have an even greater effect than blocking IL-4 and IL-13, since it is one step before turning on IL-4 and IL-13.    [20:14] That's one of the reasons researchers are excited about the promise of blocking TSLP. There are studies ongoing of TSLP blockers in people with EoE.   [20:34] Ryan asks if there are negative repercussions from blocking TSLP. Dr. Lee says in this study and in people, we are not completely blocking TSLP by any means. There will still be residual TSLP activated, even with very potent drugs.   [21:01] In the study, they block TSLP about 50%‒60%. TSLP is involved in immunity against parasites. In studies with people, they make sure not to include anybody who has an active parasitic infection. A person under treatment should not be in a study.   [21:27] Dr. Lee says we haven't seen any problems with parasitic infections becoming more severe, but that is a theoretical possibility, so for that reason, in studies with TSLP blockers, we generally exclude patients with known parasitic infections.   [22:17] What excited Dr. Lee in this paper was that they showed that when you block TSLP in the mice, then you get real effects in their tissues. Eosinophils went away. The thickening of the basal layers in the esophagus got much better.   [22:38] That kind of real effect reflected in the tissue is super exciting to see. That gives us more confidence that this could work in people, since we're seeing it in a realistic whole-body model in the mice.   [23:12] Dr. Lee says there are ongoing clinical studies on TSLP blockers for EoE. His company is studying an antibody that blocks TSLP in eczema, COPD, and EoE. One of the exciting things about immunology is that it affects many different parts of the body.   [23:42] EoE is associated with other immune-type disorders. There's a high percentage of patients with EoE who have other diseases. EoE coexists with asthma, atopic dermatitis, and chronic rhinitis.   [24:09] It's exciting that if you figure out something that's promising for one disease that TSLP affects, it could have very broad-ranging implications for a variety of diseases.   [24:22] Ryan shares his experience of his doctor talking to him about a TSLP blocker, tezepelumab, as a potential option when it's out of clinical trials. It would target something a little higher up the chain and help with some of his remaining symptoms.   [24:59] Ryan is excited to hear that this research is so encouraging and how it could potentially help treat EoE, asthma, and other conditions, all at once.   [25:16] Dr. Lee says that being in these later-stage studies is super exciting. If these late-stage trials are successful, the next step is to apply for regulatory approval with the various agencies around the world.   [26:40] Dr. Lee shares one takeaway for listeners to remember. Think of TSLP as an alarm that turns on inflammation. He compares TSLP to turning on an alarm during a robbery. There are multiple steps designed to protect the bank and the money.   [27:20] To extend that analogy, with TSLP, once you turn it on, all these other steps are going to happen. Inflammation is designed to protect the body. It's a protective response. If there's an infection, it can clear the infection.   [27:38] If the infection persists, as in HIV, the immune response, which is protective and beneficial, eventually becomes damaging. It becomes dysfunctional. In EoE, if you continually eat the allergic food, the inflammation becomes damaging to the esophagus.   [28:27] Long-term inflammation leads to replacing the normal esophageal tissue with fibrotic tissue, and that's why the esophagus eventually gets hardened and less able to let the food go through.   [28:40] In respiratory diseases, the soft tissue of the lung gets replaced with thicker tissue, and the lung is not able to expand.   [28:54] Dr. Lee says he people to think about TSLP as this master alarm switch. We hope that if you could turn off that TSLP, you could then avoid a lot of the complications that we see with chronic inflammation in these conditions.   [29:14] We're hopeful that you could even take away the symptoms that you see in these diseases, make patients feel better, and with extended treatment, you could begin to reverse some of the damage resulting from inflammation.   [29:32] Ryan likes that analogy and how Dr. Lee has concisely explained these complicated concepts.   [29:51] Dr. Lee thanks Holly and Ryan and adds one more plea to listeners. Please consider getting involved with research. Clinical trials cannot be done without patients. We need patients to advance new treatments.   [30:27] Researchers like Dr. Lee spend a lot of time thinking about how to make the studies not only informative but also fair to patients who decide to become involved. It's a lot of work and a fair amount of time commitment.   [30:44] If you don't want to be in a study, you can help by being on a patient feedback panel and reviewing protocols and informed consents. Follow your interests. Think about getting involved with research, however you can.   [31:06] Ryan and Holly are very grateful for the community, with so many wonderful clinicians and researchers, and so many patients who are willing to volunteer their time and their data to help researchers find better solutions going forward.   [31:26] Ryan thanks Dr. Lee for coming on and putting out that call to action. It's a great reminder for listeners and the patients in the community to look for those opportunities. Chat with your physician. Go to APFED's website. There's a link to active clinical trials.   [31:47] For our listeners who want to learn more about eosinophilic disorders, we encourage you to visit apfed.org and check out the links in the show notes below.   [31:53] For those looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder at apfed.org/specialist.   [32:01] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections.   [32:11] Ryan thanks Dr. Andrew Lee for joining us today. We learned a lot. Holly also thanks APFED's Education Partners Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Andrew Lee, M.D., VP Clinical Research, Uniquity Bio   "A Mouse Model for Eosinophilic Esophagitis (EoE)" Current Protocols, Wiley Online Library   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda.   Tweetables:   "I see drug development as a chance to apply cutting-edge research to benefit people." — Andrew Lee, M.D.   "When the cells that line the GI tract and the cells that line the airways in our lungs receive an insult or an injury, they get a danger signal, then they make TSLP." — Andrew Lee, M.D.   "Observational studies have found that some people with genetic variations that lead to higher levels of TSLP in their bodies had an increased risk for allergic inflammatory diseases like EoE, atopic dermatitis, and asthma." — Andrew Lee, M.D.   "There's a lot of research on TSLP, and one of the reasons we're excited about the promise of TSLP is that it's so far upstream; so much of the beginning, that it's affecting other cells." — Andrew Lee, M.D.   "Please consider getting involved with research. We can't do these clinical trials without patients. We need patients to advance new treatments for patients." — Andrew Lee, M.D.

Today we welcome on Fisheries Research Scientist at the Wisconsin Department of Natural Resources, Colin Dassow! We chat with Colin about three separate research projects he's been apart of recently, that take a critical look at the common characteristics of lakes with trophy bass potential, a shocking hook avoidance study, and the tendencies and co-mingling of pike and musky. Brought to you by: American Legacy Fishing & Outdoors www.americanlegacyfishing.com

Hey Lifers and happy Halloween!Britt really put in the effort this year but we can’t work out if she’s Gandalf or God.Do you celebrate Halloween now or did you as a kid? We share some stories from our childhood about Halloween.Britt has had a beauty mishap and Keeshia has gone wagatha mode to try and figure out which neighbour stole her bin.Is it just sex or is there emotion? When it comes to cheating, is physical or emotional worse? Lily Allen has dropped the break up album of all time that has us feeling like we are reading her diary. In it, she shares how her and her husband David Harbour (of Stranger Things fame) had an unconventional arrangement where he could have sex with other people, as long as it was ‘discreet’ and ‘paid for with strangers’. Lily later found out through snooping that David had been having an affair where they in fact, played tennis!Today we wanted to unpack one particular line in her new music “is it just sex or is there emotion” and speak about how men and women seem to view emotional vs physical cheating differently.Researchers asked what kind of betrayal, emotional or physical, would hurt more. They found that on average, men report feeling more distress over physical infidelity whereas women more often said that emotional betrayal, when a partner develops feelings or emotional closeness with someone else, was more painful. Lily described the tracks as being "inspired by" what happened in her marriage, she says they are "not gospel" and that it’s “a mixture of fact and fiction.” We share how we feel about the woman who has been ‘outed’ in this and whether you can share so much that exposes other people without being clear on what’s real and what has been made up. You can watch us on Youtube Find us on Instagram Join us on tiktok Or join the Facebook Discussion Group Hosted by Britt Hockley & Keeshia Pettit Produced by Keeshia Pettit Video Produced by Vanessa Beckford Recorded on Cammeraygal Land Tell your mum, tell your dad, tell your dog, tell your friend and share the love because WE LOVE LOVE! XxSee omnystudio.com/listener for privacy information.

What if music isn't just entertainment—but the very architecture of reality?In this paradigm-shifting episode we explore the radical proposition that vibration is not merely a metaphor. From ancient philosophy to modern neuroscience, near-death experiences to channeled symphonies, we trace a breathtaking arc across time and consciousness to uncover a unified theory: that sound, frequency, and resonance are the keys to understanding who we are, where we come from, and what reality truly is.We begin with the ancients. Pythagoras' “music of the spheres” and Kepler's celestial harmonics weren't poetic musings—they were mathematical assertions that the cosmos itself is structured like a divine instrument. From there, we zoom into the microcosm: the human being as vibrational receiver. Drawing on metaphysical sources like Andrew Jackson Davis, we explore the idea that every atom is a string in a divine orchestra, and that alignment—feeling “centered,” “in tune,” or “in one accord”—is not just metaphorical, but literal. Discord, then, becomes vibrational misalignment, a friction against the grain of existence.This sets the stage for one of the most compelling bodies of evidence: near-death experiences (NDEs). Across cultures and contexts, experiencers report hearing indescribably beautiful music—not as entertainment, but as truth made audible. Dr. Michael Newton's regression research reveals souls recognized by their unique vibrational signatures, suggesting that each consciousness is a distinct note in a cosmic symphony. Hospice workers echo this, documenting patients perceiving ethereal choral music moments before death. These accounts challenge materialist assumptions: if the brain is offline, what is doing the hearing?Next, we explore the human conduit: savants, creatives, and channelers who seem to access music not through learning, but reception. Cases like Leslie Lemke and Gloria with Williams syndrome suggest that profound musical ability may be latent in all of us, unlocked by unusual brain wiring or trauma. Dr. Alan Snyder's research proposes that inhibiting certain brain regions can temporarily reveal savant-like perception, implying that genius may be a matter of tuning in rather than building up.Then come the channeled currents. Rosemary Brown claimed to transcribe music dictated by deceased composers, while Stuart Sharp spent decades trying to capture the “Angeli Symphony” he heard after personal tragedy. Jacqueline Ott went further, channeling music from non-human intelligences—cosmic languages, liquid light, divine blueprints—suggesting a source beyond individual spirits, perhaps a universal vibrational database.This leads us to the primacy of consciousness. Drawing on quantum physics, Vedanta philosophy, and contact modality research, we explore the idea that consciousness is not produced by the brain, but fundamental to reality itself. Nobel laureates like Sir James Jeans and Erwin Schrödinger leaned toward this view, echoing ancient insights that the observer and the observed are one.If consciousness is primary, then phenomena like UFOs, NDEs, OBEs, and channeling may be different expressions of the same underlying truth: consciousness interacting with other layers of reality. Researchers like Dr. Kenneth Ring and the FREE group found that experiencers across modalities report similar transformations—less fear, more compassion, a shift toward love and service.And that's the final chord. Across all sources, the message is consistent: the purpose of consciousness is evolution. Not technological or biological, but vibrational. We are here to raise our frequency, reduce entropy, and harmonize with the larger consciousness system. The method? Unconditional love and selfless service.This episode invites you to reconsider everything—from the music you hear to the thoughts you think—as part of a cosmic composition. You are not just a listener. You are a note. A radiant tone in the divine chord.Are you in tune?

Researchers Investigate the Associations of Dental Disease,Oral Hygiene Care, and Dementia RiskBy Today's RDH ResearchOriginal article published on Today's RDH: https://www.todaysrdh.com/researchers-investigate-the-associations-of-dental-disease-oral-hygiene-care-and-dementia-risk/Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/

This week we're re-airing our episode from this past August with Paco Underhill, renowned behavioral researcher, retail anthropologist, and best-selling author of Why We Buy.Paco has spent decades studying how and why we shop—and what our behavior reveals about the changing nature of retail. In this episode, he and Dave dig into:How physical stores are evolving in a digital-first worldThe surprising shopper trend reshaping the beauty categoryWhat AI can't replicate when it comes to in-store experiencesThe friction points modern brands must solve to win customer loyaltyWhether you're in eCommerce, store design, or brand strategy, this conversation is packed with timeless insights from one of retail's most influential thinkers.Connect with Paco on LinkedInFollow Beyond the Shelf on LinkedInLearn More about It'sRapidGet the It'sRapid Creative Automation PlaybookTake It'sRapid's Creative Workflow Automation with AI surveyEmail us at sales@itsrapid.io to find out how to get your free AI Image AuditTheme music: "Happy" by Mixaud - https://mixaund.bandcamp.comProducer: Jake Musiker

Researchers from Purdue University are delaying a planned trip to attempt to find Amelia Earhart's plane.

In this solo episode, I explore The Progress Principle, a concept discovered by two Harvard researchers who studied what really drives happiness and motivation. After analyzing thousands of daily journal entries, they found that the single biggest factor that keeps people inspired isn't recognition, money, or praise—it's the feeling of making progress.  In this episode, I share how the tiniest forward motion sends a signal to the brain that says, “This feels good, do it again.” This isn't just a nice mindset trick— it's a complete rewiring of your brain's reward system. Our brains are generally wired to miss our own progress. We adapt so quickly to improvements that yesterday's dream becomes today's baseline. We also have a negativity bias; our minds cling to what's not working instead of what is. The result? We feel stuck, unmotivated, or like we're not doing enough, even when we're growing in extraordinary ways. I share exactly how to override that mental wiring with simple, science-backed tools so you can stay consistent and actually achieve your goals.  What You'll Learn: Why dopamine isn't about reward-it's about momentum. The “Done List” method that helps you reflect on and record your daily micro wins. How celebration strengthens new habits by pairing progress with positive emotion. Why asking someone else to reflect on your growth can transform your self-perception. How to reframe the “arrival fallacy” so you find joy in the journey, not just the finish line. I'll also walk you through my own story! How a conversation with my therapist sister changed how I think about effort and self-worth, and how acknowledging my small wins made me feel more capable, calm, and genuinely proud of my progress for the first time in years. If you've ever felt like you're spinning your wheels, constantly setting goals and falling off track, or measuring yourself against an impossible version of success, this episode is for you.  ✨ Homework: Pause for a moment today and write down three small things you've accomplished…no matter how ordinary they seem. Maybe you sent an email you've been avoiding, made a healthy meal, or got out of bed on a hard morning. That's progress. That's growth. That's the chemistry of momentum in real time.

Beyond visible weight gain, hidden fat can build up in organs and muscles, quietly influencing long-term health A recent study published in the European Heart Journal found that where fat collects in your body is closely tied to how quickly your cardiovascular system ages The study showed that visceral fat, liver fat, and fat infiltrating muscles were strongly linked with premature cardiovascular aging Researchers also uncovered gender-specific patterns. Men tended to accumulate more visceral and abdominal fat, while women carried more subcutaneous and thigh fat To protect your heart, shift from focusing only on weight loss to improving metabolic health. Check your metabolic markers, eat the right carbs, cut seed oils, and build strength through daily movement

Yossi Matias is the head of Google Research. He joins Big Technology Podcast to discuss the company's research efforts in areas like cancer treatment and Quantum and to discuss the relationship between research and product. Tune in to hear how Google used LLMs to generate a cancer hypothesis validated in living cells, what a “13,000×” quantum result really means, and how the research product loop turns papers into products. We also cover whether AI can automate a researcher's job. This conversation was recorded in front of a live audience at Google's Mountain View headquarters. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here's 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

There's no doubt now: introducing a small amount of peanuts to your child as early as 4 months old, reduces their chance of developing a peanut allergy! Researchers believe by making that change in recommendations, 40,000 kids didn’t develop the peanut allergy they might have, and they believe if more parents follow guidelines, more lives can be saved and improved.See omnystudio.com/listener for privacy information.

There's no doubt now: introducing a small amount of peanuts to your child as early as 4 months old, reduces their chance of developing a peanut allergy! Researchers believe by making that change in recommendations, 40,000 kids didn’t develop the peanut allergy they might have, and they believe if more parents follow guidelines, more lives can be saved and improved.See omnystudio.com/listener for privacy information.

There's no doubt now: introducing a small amount of peanuts to your child as early as 4 months old, reduces their chance of developing a peanut allergy! Researchers believe by making that change in recommendations, 40,000 kids didn’t develop the peanut allergy they might have, and they believe if more parents follow guidelines, more lives can be saved and improved.See omnystudio.com/listener for privacy information.

A former defense contractor is charged with attempting to sell trade secrets to Russia. Researchers uncover critical vulnerabilities in TP-Link routers. Microsoft patches a critical Windows Server Update Service flaw. CISA issues eight new ICS advisories. “Shadow Escape” targets LLMs database connections. Halloween-themed scams spike. Our guest is Chris Inglis, first National Cyber Director, speaking on cybercrime and the upcoming documentary on cyber war, "Midnight in the War Room". WhatsApp's missing million-dollar exploit.  Remember to leave us a 5-star rating and review in your favorite podcast app. Miss an episode? Sign-up for our daily intelligence roundup, Daily Briefing, and you'll never miss a beat. And be sure to follow CyberWire Daily on LinkedIn. CyberWire Guest Today we are joined by Chris Inglis, first National Cyber Director, speaking on cybercrime and the upcoming documentary on cyber war, "Midnight in the War Room" presented by Semperis. Learn more and check out the trailer. Selected Reading Hacking Lab Boss Charged with Seeking to Sell Secrets (Bloomberg) Dark Covenant 3.0: Controlled Impunity and Russia's Cybercriminals (Recorded Future) New TP-Link Router Vulnerabilities: A Primer on Rooting Routers (Forescout) Windows Server emergency patches fix WSUS bug with PoC exploit (Bleeping Computer) CISA Releases Eight Industrial Control Systems Advisories (CISA) Cyberattack on Russia's food safety agency reportedly disrupts product shipments (The Record) Shadow Escape 0-Click Attack in AI Assistants Puts Trillions of Records at Risk (Hackread) Trick or Treat: Bitdefender Labs Uncovers Halloween Scams Flooding Inboxes and Feeds (Bitdefender) Pwn2Own WhatsApp Hacker Says Exploit Privately Disclosed to Meta (SecurityWeek) Share your feedback. What do you think about CyberWire Daily? Please take a few minutes to share your thoughts with us by completing our brief listener survey. Thank you for helping us continue to improve our show. Want to hear your company in the show? N2K CyberWire helps you reach the industry's most influential leaders and operators, while building visibility, authority, and connectivity across the cybersecurity community. Learn more at sponsor.thecyberwire.com. The CyberWire is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices

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TikTok and other social media sites are full of mental health content—often short, grabby, first-person videos detailing symptoms for conditions like ADHD and autism. But what does this mean for teens and young adults who spend hours a day scrolling?A new study published in PLOS One analyzes the 100 most viewed TikTok videos about ADHD to assess both how accurate they are and how young people respond to them. Researchers found that about half of the videos were inaccurate or missing key context, and that the more TikToks young adults watched, the less critical they were of the content.For some, watching social videos about mental health conditions led them to better understand themselves and eventually get a proper diagnosis and treatment. For others it made them consider if they have conditions they don't meet the diagnostic criteria for.Host Flora Lichtman talks with the lead author of the ADHD TikTok study, Vasileia Karasavva, a PhD Student in clinical psychology at the University of British Columbia; and Dr. Jennifer Katzenstein, director of psychology, neuropsychology, and social work at Johns Hopkins All Children's Hospital in St. Petersburg, Florida.Guests: Vasileia Karasavva is a PhD Student in Clinical Psychology at the University of British Columbia in Vancouver, Canada.Dr. Jennifer Katzenstein is Director of Psychology, Neuropsychology and Social work and Co-director of the Center for Behavioral Health at Johns Hopkins All Children's Hospital in St. Petersburg, Florida. Transcripts for each episode are available at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.