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“Retail is constant reageren en bijsturen. Als finance loop je bijna automatisch achterop.”In deze aflevering van de CFO Podcast, spreken we met Sam Van Roosbroeck, CFO bij Claes Retail Group. De overkoepelende groep boven JBC, Mayerline en CKS.Sam kwam na een carrière bij Melexis en TriFinance bij JBC binnen als Group Controller. Via Intelligence Officer bij dit merk, groeide hij door tot CFO van de hele groep.Deze onderwerpen passeren onder meer de revue:• De faciliterende CFO versus de CFO die tegengas geeft• Prioriteiten bepalen in een omnichannel approach• De founding family als directe collega's• De KPI's die er voor Sam echt toedoen• De meetbaarheid van ROPOGeniet van het interessante gesprek met Sam!
"Wir haben das Kingdompreneurship Assessment entwickelt, damit "Himmel auf Erden durch Business" nicht nur ein netter Spruch bleibt, sondern immer mehr Realität wird, weil Unternehmer ein Werkzeug bekommen, das ihnen hilft Gottes Königreich in ihrem Kontext zu verstehen und umzusetzen." Jonathan DubowyGründer von CKS "Miss es oder vergiss es!"So lautet eine alte Management-Weisheit.Wie kann man aber Himmel auf Erden durch Business messen?Das ist eine Frage, die Jonathan Dubowy, den Gründer von CKS lange beschäftigt. Denn wenn diese Frage nicht beantwortet wird, bleibt es bei motivierenden Ideen und Konzepten, die aber nachhaltig nichts verändern. Und Jesu zentrale Lehre vom Königreich wird auf ein nett klingendes Buzzword ("Kingdom XYZ") reduziert, mit dem immer mehr Gruppierungen jonglieren, anstatt wirklich Gottes ultimative Dimension zu erleben.Seit 25 Jahren brennt das Herz von Jonathan Dubowy, dem Gründer von CKS, für Befähigung, die Hirn, Herz und Hand aktiviert. Deswegen hat er in den letzten beiden Jahre das Kingdompreneurship Assessment entwickelt. Ein Onlinefragebogen, der Kingdompreneuren hilft zu verstehen wie ihr Unternehmen zu mehr Himmel auf Erden beitragen kann und wo sie dabei aktuell stehen. Das Resultat ist ein Assessment, das auf fünf "Früchten des Königreichs" basiert, die im Unternehmenskontext als fünf Kapitalformen operationalisiert werden: Gerechtigkeit (Missional Capital), Herrlichkeit (Spiritual Capital), Liebe (Social Capital), Lebendigkeit (Human Capital) und Frieden (Financial Capital). Mit insgesamt 60 Fragen zu 20 verschiedenen Aspekten des Unternehmertums bietet das Tool konkrete Ansatzpunkte für Kingdom-orientierte Transformation.Jonathan ist davon überzeugt, dass sich durch diese Neuausrichtung fast alle unternehmerischen Probleme, wie Mitarbeitermangel, Überarbeitung, zu wenig Umsatz ... lösen lassen. "Denn Gott möchte, dass seine Kingdompreneure erfolgreich sind." Aber anders, als die meisten Ansätze und Modelle adressiert das Kingdompreneurship Assessment nicht die Symptome, sondern die Wurzeln.Und das Beste, du kannst hier das Assessment direkt selber und kostenlos nutzen, für mehr Himmel in und durch dein Business: test.kingdompreneurship.deZentrale Themen der Episode:
There's lots to like about where this team is headed, and in the same breath much that could keep you up at night. One thing is for certain is we are on the brink of a sure to be exhilarating 10th season under CKS. Georgia Mens Basketball took an L to open the tournament but we are optimistic about where the program is headed and hope to see many more tournament appearances. We are 2 weeks out from G-Day. We will be here throughout. Thanks for listening.Go DAWGS !
Next week we'll kick off Season Five of Formosa Files! A huge thank you to the Frank C. Chen Foundation for its continued support of the program; without it, this podcast would not exist.In S4 we talked a lot about the 1624-2024 anniversary of the arrival of the Dutch, the new historical novel “A Tale of Three Tribes in Dutch Formosa,” and other Dutch-in-Taiwan-related things, and today we're staying on the topic with a short, informal chat about Koxinga's father.We'll cover his incredible story in future episodes, but this is his basic bio, a simple telling of his epic win at the Battle of Liaoluo Bay, and a few hints about his unhappy end.THANK YOU FOR LISTENING! And thanks for following us on social media, for the wonderful reviews and emails filled with high praise… all very much appreciated.In Season Five we're going to turn it up with big names like CKS (maybe Mao as well!), plus historic milestones such as the 2000 Presidential Election (and maybe the 2004 Chen Shui-bian shooting as well!).Catch you next week!
No próximo episódio do LowOpsCast, temos a prazer de receber Matheus Ulisses (https://www.linkedin.com/in/matheus-ulisses/), Gerente de Engenharia de Software e Qualidade, especialista em .NET, Kubernetes e Backstage. Com mais de 13 anos de experiência na liderança de projetos complexos e inovadores, Matheus se destaca como um verdadeiro Kubestronaut (CKA, CKAD, CKS, KCNA e KCSA) e Certified Backstage Associate. Ele é apaixonado por resolver problemas desafiadores e construir soluções escaláveis que geram alto impacto.
No próximo episódio do LowOpsCast, temos a prazer de receber Matheus Ulisses (https://www.linkedin.com/in/matheus-ulisses/), Gerente de Engenharia de Software e Qualidade, especialista em .NET, Kubernetes e Backstage. Com mais de 13 anos de experiência na liderança de projetos complexos e inovadores, Matheus se destaca como um verdadeiro Kubestronaut (CKA, CKAD, CKS, KCNA e KCSA) e Certified Backstage Associate. Ele é apaixonado por resolver problemas desafiadores e construir soluções escaláveis que geram alto impacto.
Send us a textVandaag aan de microfoons: Bart en Anaïs Claes van Claes Retail Group (JBC, CKS, Mayerline,…) naar aanleiding van hun overwinning van de Mercuriusprijs 2024 met het innovatieve JBC Op-Nieuw project! In deze aflevering duiken we diep in hun duurzame missie, met dit project als voorbeeld. Ze delen hoe de Claes Retail Groep duurzaamheid op maat integreert binnen hun merken. Ontdek hoe familiebedrijven, met langetermijnvisie en toewijding, een blijvend verschil maken in retail. Een inspirerend gesprek over het vieren van elke stap, groot of klein, richting een duurzame toekomst.In deze podcast gaan we in gesprek met eigenzinnige retailerondernemers die zich met hun unieke visie weten onderscheiden in hun branche. Dat doen we om onze brede community van retailers en retailondernemers, #teamretail, te inspireren positief naar de toekomst te kijken. De podcast wordt gehost door Tim Gielen, oprichter van design studio Wave of Engagement die de winkel, showroom & hospitalityconcepten van morgen bedenken en ontwerpen.Heb je plannen, ideeën die je wil uitwerken contacteer ons dan op tim@waveofengagement.com Sponsor: https://solutions.dobit.com/
Kingdompreneurship-Podcast Episode #22 on Air "Was ist der Zustand der Welt, wenn es uns nicht mehr braucht (Vision) und was ist unser Beitrag dazu (Mission). Wann nimmt man sich Zeit in der Familie darüber zu reden?" Daniel Terner Start-Up-Mentor & Founder OKR für Paare 11. September 2002 nicht nur das World Trade Center stürzt ein, sondern auch das bisherige Leben von Daniel Terner. Erst verliert er seinen Job in der Werbeagentur, deren Nachfolger er werden sollte, weil sein Chef ihn für unbrauchbar hält ("Terner du bist für nichts mehr zu gebrauchen") und dann verliert er sein zuhause, weil seine Ex-Frau ihn mit ihrem Chef betrogen hatte. Doch in Mitten all diesen Zerbruchs gab es auch einen Neuanfang, denn zum ersten Mal hat Daniel in der Band seiner Gemeinde Musik gemacht. In dieser Podcast-Episode wird es wieder sehr persönlich, weil Daniel uns hineinnimmt in seine persönliche Geschichte. Einerseits geht es um seine beruflichen Stationen vom Geschichtsstudium, über seinen Aufstieg in und mit einem Softwareunternehmen bis in die Selbstständigkeit. Andererseits geht es auch um seine persönliche Reise, vom jungen Vater von 2 Kindern, zum wiederverheirateten Patchworkvater von 4 Kindern und welche Rolle der Glaube in all dem immer wieder gespielt hat. Um die Komplexität dieser Situation zu meistern, hat er gemeinsam mit seiner Frau Christiane, das angewendet, was ihm auch im beruflichen Alltag geholfen hat Projekte und Chaos zu meistern, die OKR-Methode (Objectives & Key Results). Ursprünglich von Intel entwickelt, hat Google mit seinem Erfolg, diese Methode so bekannt gemacht, dass sie heute in den Standardkoffer agiler Unternehmen gehört. Aber Terners waren wohl die Ersten, die Vision, Mission, Strategische Felder, Quartalsziele, Weeklys und Co zum proaktiven Gestalten des Familienalltags verwendet haben. Klingt ein bisschen zu verrückt? Ja das hören sie oft. Trotzdem haben sich schon 70 Paare auf den Prozess von OKR für Paare eingelassen und sind dankbar dafür. Wir bei CKS finden den Ansatz so spannend, dass wir Daniel eingeladen haben einen Crashkurs am 08.11. im Rahmen des Kingdompreneurship Summits für alle durchzuführen, die Bock haben auf weniger zu viel und mehr zu zweit. Hier geht es zur Anmeldung CKS-summit.com Weil Daniel, aber nicht nur OKR-Experte ist, sondern auch für Transformation und Start-Ups, die zu einer besseren Welt beitragen, enthält diese Episode viele weitere wertvolle Nuggets. Zentrale Themen der Episode: Tipps für "weniger Reden und mehr Machen "Die OKR-Methode im Familienalltag Königreich im Businessalltag leben Warum "Nicht jetzt" besser ist als "Nein" Wie Gott führt Die Relevanz der guten Botschaft im Jahr 2024 Tipps zum Start in die Selbstständigkeit uvm. Wenn dir diese Episode gefällt gib uns 5 Sterne, kommentiere und teile sie. Gute Unterhaltung wünscht dir deine CKS-CREW #Kingdompreneurship #Inspiration #OKRs #WorkLifeIntegration #wenigerzuvielmehrzusammen #Family #PersonalGrowth
Did you know that when the United Nations voted to admit “Red China” in 1971, then-California Governor Ronald Reagan called up President Richard Nixon and suggested that the United States quit the UN and become an “observer” in protest? To some, Reagan was and is controversial, but when it comes to support for the Republic of China (Taiwan), there is no debate: Reagan thought Nixon and – especially Carter – were wrong to “throw a loyal friend overboard.” Reagan came to Taiwan twice. The first time, in 1971, he was here as a reluctant envoy of Nixon on a mission to try and calm the fears of CKS over Nixon's upcoming meeting with Mao in Beijing. During the second visit, as a private citizen in 1978, Reagan met with leader-in-waiting Chiang Ching-kuo and went back to the US full of praise for a modernizing Taiwan. When President Carter switched diplomatic relations from Taipei to Beijing, Reagan stated that the US didn't get enough out of it. He pointed out that China was the “supplicant,” and therefore in a position of weakness, and Reagan said that the precedent of betraying a friend would not be forgotten by other friends of the US. Maybe he had a point. Visit formosafiles.com for links to videos, pics, info and more. And check out our other podcast about books: Bookish Asia.
In this episode of the Dutch Kubernetes Podcast, hosts Ronald Kers and Jan Stomphorst sit down with two special guests from the Cloud Native Computing Foundation (CNCF), Audra Montenegro and Katie Greenley, to discuss the growth of Kubernetes and the role of the CNCF in supporting the global Kubernetes community.Audra is a core program manager at CNCF, overseeing the Kubernetes Community Days (KCD) and Cloud Native Community Groups (CNCG) programs. Katie, on the other hand, has been with CNCF for nine years and manages community and marketing, focusing on ambassador programs, event marketing strategies, and supporting CNCF projects.The conversation begins with introductions and an exploration of each guest's role at CNCF. They dive into topics such as Kubernetes certifications, including the CKA, CKAD, and CKS, which validate expertise in Kubernetes administration, application development, and security. Audra and Katie emphasize the importance of these certifications and the commitment required to achieve them.The episode also touches on the planning of large-scale events like KubeCon, how these events continue to evolve, and the CNCF's growing global influence. Both guests share insights into the CNCF's Ambassador Program, explaining how community members can contribute and gain recognition by organizing events, writing content, or leading meetups.A strong focus is placed on diversity and inclusion in the community, with both Audra and Katie highlighting CNCF's initiatives to foster a more diverse and inclusive environment. The conversation wraps up by discussing the future of Kubernetes, the rise of platform engineering, AI, and the increasing importance of sustainability in tech eventStuur ons een bericht.ACC ICT Specialist in IT-CONTINUÏTEIT Bedrijfskritische applicaties én data veilig beschikbaar, onafhankelijk van derden, altijd en overalDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.
„Ich hab das Geld meiner Familie in das Business investiert und deswegen wusste ich, dass ich erfolgreich werden muss, sonst hätte es sich wie Diebstahl an meiner Familie angefühlt."Dani Goeppert (37) Founder Risen Events - Österreich Willkommen zu einer inspirierenden Reise durch Glaube und Unternehmertum! In dieser fesselnden Episode des Kingdompreneurship Podcasts spricht unser Gast Dani Göppert über ihre einzigartige Reise als sechsfache Mutter und erfolgreiche Online-Unternehmerin. "Business ist eine der besten Jüngerschaftsschulen", sagt Dani und teilt ihre wertvollen Einsichten über die Integration von Familie, Business und Glauben.Dani Göppert, ist eine dynamische Unternehmerin aus Kanada.In Israel, Deutschland und der Urkaine war sie als Missionarin unterwegs und weiß wie es ist als Familie mit 200€ im Monat über die Runden zu kommen. Mit Business wollte die gelernte Opernsängerin nichts zu tun haben.Auf einem der ersten Start-Up-Weekends von CKS hatte sie dann allerdings einen "Erleuchtungsmoment" - Jüngerschaft kann auch durch Business passieren. Glaube und Unternehmertum müssen keine getrennten Bereiche sein, sondern gehören zusammen.Diese Erkenntnis, hat Dani motiviert ein Business aufzubauen, das 3 Ziele verfolgt. Arbeit von zu hause, um für die Familie da zu sein Himmel auf die Erde bringen Die Familie finanziell stärken All das ist ihr gelungen mit der Gründung von "Risen Events", ein Unternehmen, das sich auf Online-Events und Marketing für Coaches, Trainer, Speaker und alle die durch ihre Expertise Geld verdienen wollen spezialisiert hat. Inzwischen hat sie ein international verteiltes Team aufgebaut mit dem sie Events mit bis zu 10.000 Teilnehmern organisiert.Besonders inspirierend ist, dass Dani sich entschlossen hat herausfordernde Lebensumstände umzudeuten in Begründungen, warum sie erfolgreich wird.Keine Zeit, keine Idee, kein Geld, kein Erfolg ... ist für Dani kein Grund nicht zu starten und nicht erfolgreich zu werden und als Mutter von 6 Kindern, weiß sie wovon sie spricht.Zentrale Themen der Episode: Von Mission zu Business: Wie Dani Göppert ihre Berufung fand und ein erfolgreiches Unternehmen aufbaute. Work-Faith-Family Integration: Praktische Tipps zur Vereinbarung von Familie und Business, einschließlich Zeitmanagement und der Bedeutung von Pausen. Glaube als Leitfaden: Dani spricht über die Rolle ihres Glaubens in schwierigen Zeiten und wie sie Gottes Führung in ihren unternehmerischen Entscheidungen erlebt hat. Herausforderungen als Chancen: Eine ermutigende Perspektive auf Hindernisse und wie sie als Sprungbrett für Wachstum genutzt werden können. Lass dich von Dani Göpperts Geschichte inspirieren und finde heraus, wie du deine beruflichen und persönlichen Ziele mit deinem Glauben in Einklang bringen kannst. Wir freuen uns über dein Feedback und ermutigen dich, diese Episode mit Freunden und Kollegen zu teilen, die von einer solch inspirierenden Botschaft profitieren könnten. Gute Unterhaltung wünscht dir dein CKS-Team#Kingdompreneurship #Work-Faith-Family-Integration #Online-Business #Unternehmertum #Familienmanagement #NoExcuses
„Wir haben in 2 Jahren und 7 Monaten aus 76.000 Dollar Schulden ein 110 Millionen Dollar Unternehmen aufgebaut. Heute hat die Unternehmensgruppe einen Wert von über 3 Milliarden € (...) Mein Auftrag ist es aus Australien die erste "Schafs-Nation" der Neuzeit zu erschaffen." Dave Hodgson (68) Founder & CEO Paladin Corporation - Australien David Hodgson ist ein Kämpfer durch und durch. Im Unabhängigkeitskrieg von Simbabwe hat er 10 Jahre lang für die britische Eliteeinheit SAS und die noch härteren Selous Scouts hinter feindlichen Linien gefährlichste Einsätze ausgeführt. Vor der japanischen Küste, hat er als Tiefseetaucher den Angriff einer Riesenkrake überstanden. Heute sieht er diese und andere Herausforderungen als sein "Life's Training", die ihn vorbereitet haben, eine göttliche Spezialmission auszuführen: Aus Australien die erste "Sheep-Nation" zu erschaffen. Damit bezieht er sich auf die Passage aus Matthäus 25,31ff in der Jesus beschreibt, dass es Nationen bei seiner Rückkehr geben wird, die seinen Willen getan haben, in dem sie sich um Hungernde, Kranke, Gefangene usw. gekümmert haben. Und diese Nationen wird er als Schafe zu seiner Rechten sammeln, um ihnen sein Reich als ewiges Erbe zu geben, während die Nationen, die diesen Willen nicht umgesetzt haben als Böcke eine ewige Strafe erhalten werden. Dave's Strategie das zu erreichen ist es zu demonstrieren, das wirtschaften auf Gottes Art und Weise ("Caring & Sharing") für alle Stakeholder (Eigentümer, Kunden, Lieferanten, Mitarbeiter, Wettbewerber usw.) zu besseren Ergebnissen führt, als alle anderen Wirtschaftssysteme, die auf Gier & Selbstzentriertheit aufbauen. Australien soll dann als Blaupause für andere Nationen dienen, die dem Beispiel folgen wollen. Himmel auf Erden durch Business. Läuft. Für alle. würden wir bei CKS dazu sagen ;-) Das besondere an Dave`s Ansatz ist, dass er ein Mann der Praxis ist und seine Überlegungen und Erkenntnisse in die Tat umgesetzt hat, wodurch er die Paladin Unternehmensgruppe erschaffen hat. Ein Verbund von über 30 Unternehmen im Wert von über 3 Milliarden Dollar, die er gegründet oder aufgekauft hat. Für Dave ist klar: Bevor Jesus wiederkommt, wird die gute Botschaft von Gottes Königreich der ganzen Welt demonstriert werden und zwar nicht durch Worte allein. Am besten gibt die Passion Translation diesen Gedanken aus Matthäus 24,14 wieder: “Yet through it all, the good news of heaven's kingdom will be proclaimed all over the world, providing every nation with a demonstration of the reality of God. And after that, the end of this age will arrive.” Highlights & Key-Learnings dieser Episode: Jesus ökonomische Strategie, die du noch nie gehört hast Wie du deinen Lebensauftrag erkennst Warum die Bibel keine Rente kennt und was einen lange leben lässt Wie Deutschland zum Besseren verändert werden kann Warum es besser ist seinen Wettbewerber nicht zu besiegen Wieso Initimität mit Jesus das alles Entscheidende ist Wer mehr über Dave und seine inspirierenden und praktischen Teachings erfahren will, dem empfehen wir eine Mitgliedschaft in seiner Community Kingdom Initiatives #KingdompreneurPodcast #Vision #Lebensauftrag #Transformation #Cocreation #MissionImpossible #ChangeaNation P.S. Wie immer freuen wir uns über Feedback zu dieser Episode. Wenn du möchtest, dass wir Dave über ein Webinar oder für ein Live-Event nach Deutschalnd holen dann schreib uns an podcast@creative-kingdom-solutions.com P.P.S. Ein zentrales Thema bei Dave ist zu verstehen, welchen spezifischen Aufrtrag Gott einem gibt, um ihn zu erledigen. Er nennt es "Assignment". Wir finden dieses Thema so wichtig, dass wir ihm unser erstes SNACKS2GROW Video gewidmet haben. Du findest es hier auf unserer Webseite: https://creative-kingdom-solutions.com/snacks2grow-1 und am Ende der Seite kannst du dir auch ein hilfreiches Arbeitsblatt dazu runterladen.
"Wir brauchen keine Evangelisationseinsätze, um Menschen zu erreichen, sondern einen Lifestyle, der die Welt in das eigene Leben integriert und genau das habe ich im Unternehmertum gefunden." Dennis Penner 5-fach Vater & Gründer der Recruitingagentur HELLO AD! Schon als Kind hatte Dennis Penner den Traum Unternehmer zu werden, aber bis es soweit war, mussten erst noch einige Hürden genommen werden. Schwierige Kindheit, Hauptschule, Missionar in Südafrika, abgebrochenes Gemeindepraktikum, abgebrochenes Bibelschule, abgebrochenes Bauingenieursstudium, Medizintechniker, Hochzeitsfotograf, berufsbegleitendes Studium, Kündigung, eigene Marketingagentur. Und zwischendrin ist die Familie auf 7 Köpfe angewachsen. Wie das genau passiert ist, was Dennis in der Zeit mit Gott erlebt hat, wie durch seine Recruitingagentur HELLO AD! mehr Himmel auf die Erde kommt, aber vor allem, wie es ihm gelingt die Beziehung zu seinen 5 Kindern zu priorisieren, während sein "Business-Baby" besonders laut schreit, erfährst du in dieser Episode des Kingdompreneurship-Podcasts. Übrigens ist Dennis Geschichte so spannend, dass der Business Insider ein Interview mit ihm geführt hat: "Business Insider_Ich bin CEO und Vater von fünf Kindern" den ganzen Artikel kannst du dir hier herunterladen Highlights & Key-Learnings dieser Episode: Tipps, wie Familie und Business zusammen gelingt 3 Wege wie Himmel auf Erden durch Business kommt Die Gefahren von "Bubbles" und die Grenzen von Missionseinsätzen Warum Väter die besseren Unternehmer sind Was in Momenten von Zerbruch tragen kann #KingdompreneurPodcast #Familiy #Missions #Glaube #Gründung #Marketing #Success Übrigens ist uns bei CKS "Work-Faith-Family-Integration" so wichtig, dass wir unser diesjähirges Hauptevent, den Kingdompreneurship Summit diesem Thema widmen. Deswegen trag dir jetzt schon mal den 8. und 9. November in Karlsruhe dick und fett im Kalender ein, damit du dieses Event auf keinen Fall verpasst.
Two games for this episode, featuring a Virat Kohli masterclass v Punjab Kings. The RCB batter was imperious as he blasted 92 runs at almost 2 a ball, a statement of intent by Virat Kohli before he heads to the World Cup with India. Punjab Kings have now been eliminated, and Dan Weston joins us to talk about their season and where it went wrong. Later in the show we talk CSK v Gujarat Titans. This was a huge game for CKS, but Shubman Gill and Sai Sudharsan both hit tons, putting their IPL play-off qualification at risk. Head to Serious Cricket to find your cricket gear for 2024: www.serioussport.co.uk/cricket?af=the-cricket-podcast Use the code: CRICKETPOD for 20% off + free shipping at Manscaped.com Links to podcast audio: https://linktr.ee/thecricketpod Our website: thecricketpod.com Support the podcast: patreon.com/thecricketpod Buy merchandise: https://seriouscricket.co.uk/teamwear/stores/the-cricket-podcast/ Facebook: https://www.facebook.com/thecricketpod Buy coffee: https://cricketcoffeeco.com/products/the-cricket-podcast-coffee Twitter and Instagram: @thecricketpod Want to create live streams like this? Check out StreamYard: https://streamyard.com/pal/d/6313687373840384 Learn more about your ad choices. Visit podcastchoices.com/adchoices
В данном выпуске у нас "на кухне" в гостях Виктор Николаев, развивающий платформу-тренажер для подготовки к Kubernetes сертификации. В выпуске мы обсудим саму платформу, как и чем она живет и много всего интересного. ССЫЛКИ
Gyalo Thondup རྒྱལ་ལོ་དོན་འགྲུབ has had a very interesting life. Born in 1927, he's the second-eldest brother of the current (and 14th) Dalai Lama. Brother Thondup has long been an unofficial envoy for the Tibetan leader-in-exile, and in May 1950, Gyalo Thondup became the first “officially acknowledged” Tibetan to visit Taiwan since 1949. What was he doing here? Why Taiwan? What were then-president CKS's feelings about Tibet? Find out in this week's Formosa Files episode. See pics and more at formosafiles.com
Boom! We break our own record for outscoring the hell out of a P5 opponent! That's what a committed culture vs. not committed looks like. CKS called it in his post game presser. It was sublime for the fans at the stadium and at home! Go Dawgs!! CLICK HERE FOR A HAT IN OUR STORE!!
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Jesusnachfolger, gründen, übernehmen und führen in COCREATION mit dem 3-einigen Gott gesunde & wachsende Unternehmen, die ein Stück Zerbrochenheit heilen und durch all das Himmel auf Erden demonstrieren." Jonathan Dubowy Founder CKS Highlights & Key-Learnings dieser Episode: 1. Warum entscheidend ist, wer die beste Story erzählt 2. Warum opportunistisch ein guter Startpunkt, aber ein schlechter Endpunkt ist 3. 3 Beispiele von Kingdompreneurship in der Praxis 4. Die 4 Leitfragen, um von Zerbrochenheit zu Erlösung zu kommen 5. Wie die Geschichte der verlorenen Söhne weitergeht Helping Kingdompreneurs win! Das ist unsere Mission bei CKS. Deswegen haben wir Anfang diesen Jahres den Kingdompreneurship-Podcast gestartet, um die echten, himmlischen und hilfreichen Stories derer zu erzählen, die aus unserer Sicht als Kingdompreneure unterwegs sind (selbst wenn sie sich selbst gar nicht so beschreiben würden). Das tun wir, weil wir davon überzeugt sind, dass wir die Geschichten von denjenigen erzählen und diejenigen feiern müssen, die bereits tun, was wir noch häufiger sehen wollen. Und so durften wir dieses Jahr schon 9 spannende Stories erzählen. Aber wer genau ist eigentlich ein Kingdompreneur? Unsere Kurzantwort darauf lautet: ein Kingdompreneur ist jemand, der möchte, dass in und durch sein Unternehmen etwas vom Himmel auf Erden erlebbar wird. Es ist jedenfalls nicht einfach ein Christ, der ein Unternehmen hat. Ehrlicherweise bleibt die Kurzversion, aber noch etwas vage und an der Oberfläche. Tatsächlich geht unser Verständnis noch etwas tiefer und es umfasst 2 Dimensionen: 1. Das Unternehmen und seine Grundausrichtung: warum, wie und was das Business tut. 2. Der Unternehmer und seine Identität: Sein Credo und Sein WHO, also seine Sicht auf Gott, sich selbst und die Welt. In der aktuellen Podcast Folge leitet Jonathan unser Verständnis von Kingdompreneurship her und illustriert die Theorie mit praktischen Beispielen. Dabei sind unsere Modelle und Konzepte, offen gesprochen, immer nur Momentaufnahmen und nicht der Weisheit letzter Schluss. Deswegen heißt es in unserem Mission Statement auch: "Wir alle sind eine Bewegung von Menschen, die Jesus im Herzen und Business im Kopf haben und mit dem Heiligen Geist Schritte gehen." Es geht uns um die Bewegung nach vorne und dass wir uns gegenseitig inspirieren, voneinander lernen und uns gemeinsam für mehr Himmel auf Erden durch Business einsetzen. Und aus diesem Grund ist es uns wichtig zu betonen, dass die Kingdompreneur-Journey nicht erst da beginnt, wo ein erfolgreiches Unternehmen bereits zu sehen ist, sondern, an dem Moment, wo das Interesse beginnt, mehr über die Integration von Glauben und Unternehmertum zu lernen dem C1-Level. Es ist unser Commitment Kingdompreneure auf dem Weg von C1 bis zu C5 zu begleiten, damit sie persönlich, praktisch und geistlich erfolgreich sind. Das meinen wir, wenn wir sagen. Helping Kingdompreneurs win. Wie freuen uns von dir zu hören und deine Meinung und dein Verständnis von Kingdompreneurship kennen zu lernen. Wo kannst du uns zustimmen, was fordert dich heraus und wo bist du der Meinung liegen wir noch nicht ganz richtig? Wir haben den Kingdompreneurship Podcast gestartet, weil wir glauben, dass Kingdompreneure, egal wo sie auf ihrer Reise stehen, Inspiration und Ermutigung brauchen - nicht weil die Welt einen weiteren Podcast braucht. Deswegen wollen wir die echten Stories & Learnings von Kingdompreneuren erzählen, die auf ihre Art und Weise und in ihrem Kontext in COCREATION mit Gott ein Stück mehr Himmel auf die Erde bringen, denn das heißt es ein Kingdompreneur zu sein. Jetzt interessiert uns vor allem Dein Feedback. Was lernst Du, wie inspiriert Dich der Podcast und wovon wünschst Du Dir noch mehr? Schreib uns einfach an: podcast@creative-kingdom-solutions.com Und wenn es Dir schon richtig gut gefällt, erzähl es weiter, like und share unseren Podcast. Wir wünschen Dir eine richtig gute Zeit, dein CKS-Team
В этом видео мы подробно рассмотрим последний релиз Terraform 1.5 и то, что он предлагает профессионалам в области DevOps. Также мы обсудим значительное изменение в лицензионной модели HashiCorp, поскольку они переходят к лицензии Business Source License (BSL). Подробнее о смене лицензии можно прочитать здесь. Кроме того, мы изучим различные сертификации Kubernetes, включая CKS, CKA и CKAD, и расскажем, какая из них подойдет именно вам. Основные моменты: Terraform 1.5: Что нового? Переход HashiCorp к BSL: Что это значит для сообщества открытого исходного кода? Сертификации Kubernetes: CKS, CKA, CKAD - Какую выбрать? Новости вкратце: Будьте в курсе последних новостей в мире IT. Новая рубрика!!! 00:00:00 - Start 00:01:22 - Мы шоу или не шоу? 00:02:04 - Хорош ли интернет в Германии? 00:04:27 - HashiCorp поменяли лицензию - Terraform все? 00:28:35 - Terrafom 1.5 00:30:01 - Terrform 1.5 - Import 00:39:14 - Terrform 1.5 - Check 00:42:51 - Terraform 1.6 alpha 00:45:27 - Интеграционное тестирование в Terraform 00:57:48 - Terraform AWS prodivder 5.0 01:01:44 - AWS новый регион - Tel Aviv 01:04:39 - Чем отличаются сертификации в K8S (CKA,CKAD,CKS) 01:07:21 - Ссылка на CKA эпизод - про сдачу 01:10:10 - Вопрос от слушателей 01:17:04 - Новая рубрика! 01:22:52 - K8SGPT
Kingdompreneure machen Unmögliches möglich, weil sie einen Gott an ihrer Seite haben, der aus nichts alles erschaffen hat. Die Story von Shift ist genauso eine "unmögliche". Denn im Jahr 2014 in Deutschland ohne externes Geld von Banken oder professionellen Investoren ein Unternehmen zu gründen, um das fairstmögliche Smartphone auf den Markt zu bringen ist schon ziemlich crazy. Aber es hat geklappt und die Story von https://www.shift.eco/ geht weiter. Was den Gründer Carsten Waldeck dabei antreibt, was er dabei gelernt hat und was er anderen unternehmerischen Weltveränderern und solchen die es werden wollen empfiehlt, erfahrt ihr in dieser Folge unseres Kingdompreneurship Podcasts by CKS - lass dich inspirieren. Verpasse keine Neuigkeiten, folge uns auf unseren Kanälen: LinkedIn: https://www.linkedin.com/company/creative-kingdom-solutions/ Instagram: https://www.instagram.com/creativekingdomsolutions/ Newsletter: https://creative-kingdom-solutions.com/#newsletter
Die Mission von CKS also Creative Kingdom Solutions ist es Kingdompreneur zu helfen erfolgreich zu sein, damit mehr Himmel durch Business auf die Erde kommt. Klingt ein bisschen crazy und das ist es auch, weiß in jedem Fall derjenige, der das Ganze in 2017 gestartet hat: Jonathan Dubowy. Wie es dazu kam, welche Rolle ein Frühstücksriegel, den es nie gab, spielt und welche Basics zu Kingdompreneurship jeder christliche Unternehmer einmal gehört haben sollte, erfährst du in dieser unserer ersten Folge.
Christmas came early for the Georgia Bulldogs as Kirby and Company have put together another AMAZING defense-focused recruiting class for 2023 on day 1, highlighted 5-star EDGE Damon Wilson and followed that up with 4-star DT Jordan "Big Baby" Hall and Transfer WR Ra Ra (ah-ah-ah) Thomas from Mississippi State (RIP Mike Leach) on day 2. UGA currently sits @ #2 in recruiting rankings, but as of now only 2 players, Bill Norton and Arik Gilbert, have entered the transfer portal showing why CKS is the gift that keeps on giving. Wishing a Merry Christmas to all in DawgNation who celebrate and can't wait to close out 2022 with a big win. Go Dawgs!
What are the best websites to use for UK General Practice? Click more for the links in the time stamps below.
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Conor is the founder of CKS - an advisory firm focused on fundraising and M&A. Since 2020 alone, CKS has advised on over half a billion dollars in trade sales, and helped raise over $125m for their clients. Conor is also an active angel investor. He took the time to share some of his insights with us in this episode!
Joey Alvarado is a world renowned fitness/mma and bjj coach. Sensei Joey is a 30 year veteran of martial arts training. Joey aka "Kettlejitsu" fused traditional kettlebell exercises with movements from mma and Brazilian Jiu Jitsu and came out with the ground breaking dvd, Combat Kettlebell Systems. The CKS dvd sold in over 30 countries world wide. This made Joey an innovator in the world of kettlebell training ___Time Stamp 00:00 Joey's Kettle-Jitsu Story 12:50 The Relation Between Jiu Jitsu & Kettlebells 30:00 Joey's Kettle-Jitsu Story Part II 57:00 Building Superpower 1:10:00 Does Pavel Tsatsouline Even Lift? 1:32:00 Martial Arts & Kettlebells --- Send in a voice message: https://anchor.fm/lebe-stark/message
Gavin Pitcher is Head of Corporate Finance and Technology Advisory for CKS Finance. In this episode, Gavin speaks about all things CKS and how they are on a track to become the premier Corporate Finance advisory in Ireland.
Patreon... because you want to support our goofy asses www.patreon.com/accidentaldads So thank you to a beautiful and wonderful listener, we decided to do an addendum to our top police stings and follow it up with the top most dangerous mobs/gangs of all time. La Cosa Nostra One of the biggest threats to American civilization from organized crime is the Cosa Nostra, sometimes referred to as the "Mob" or the "Mafia," which sprang from the Sicilian Mafia. The term "La Cosa Nostra," used by the US government, and "Cosa Nostra" by its members literally translates to "this thing of ours" or "our thing." This international organization of criminals, made up of many "families," is committed to combating crime and defending its members. These organized and major racketeering activities are being carried out by these crime families or groups, which are connected by kinship or by conspiracy. A wide range of illicit activities, including as murder, extortion, drug trafficking, government corruption, gambling, infiltrating lawful enterprises, labor racketeering, loan sharking, prostitution, pornography, tax fraud schemes, and stock manipulation are also engaged in by them. The Cosa Nostra is most prevalent in the urban areas of New York City, New England, and portions of New Jersey, Philadelphia, Detroit, and Chicago. The Bonanno, Colombo, Gambino, Genovese, and Lucchese families are among the prominent ones in the New York City region. Sometimes, members and associates of one La Cosa Nostra family collaborate with members of other La Cosa Nostra families to carry out joint criminal activities. Within these families, members collaborate on "crews" that are commanded by a "capo" or "captain," who is in charge of overseeing his crew's illicit actions and offering them assistance and safety. The crews are made up of trusted outsiders known as "associates" and "made" members known as "soldiers." An associate must be of Italian heritage, have proven their capacity to make money for the Family, and have shown a willingness to use violence in order to become a "made member" of the Family. The three highest-ranking members who manage the Family are the Boss or Acting Boss, the Underboss, and the Consigliere, or advisor. Cosa Nostra has its origins in Italian organized crime, although it has existed as a distinct organization for a long time. It still collaborates with many criminal organizations with Italian headquarters today in a variety of illicit operations. Labor racketeering, in which it attempts to dominate, manage, and control a labor movement in order to have an impact on associated businesses and industries, is one of its main sources of income, power, and influence. Organized criminal organizations may profit greatly from labor unions, particularly their pension, welfare, and health funds. The mafia tries to regulate these schemes by giving businesses "sweetheart" contracts, cordial worker relations, and weak work regulations, or by manipulating union elections. Large cities like New York, Buffalo, Chicago, Cleveland, Detroit, and Philadelphia that have robust industrial bases and labor unions tend to be the epicenters of labor law infractions. Additionally, there are several organized criminal characters in these cities. Labor racketeering costs the American public millions of dollars annually through increased labor expenses that are ultimately passed on to consumers, according to many FBI investigations. In order to investigate potential violations of labor law, the FBI collaborates closely with other governmental organizations and uses methods such as electronic surveillance, covert operations, use of secret sources, and victim interviews. The passing of the Racketeer Influenced and Corrupt Organizations Act (RICO) in 1970 was the one event that helped more than anything else to deter organized crime. The agencies were able to work more effectively as a result of this action because they could target the entire corrupt organization rather than incarcerating individuals who might simply be replaced by other members or affiliates of organized crime. The first known Sicilian Mafia member to immigrate to the United States was Giuseppe Esposito. After assassinating 11 rich landowners, the chancellor and vice chancellor of a Sicilian province, and six other Sicilians, he escaped to New York. In 1881, he was detained in New Orleans, Louisiana, and then sent back to Italy. The nation's first significant Mafia event occurred in New Orleans. Police Superintendent David Hennessey of New Orleans was executed on October 15, 1890. Numerous Sicilians were detained, and 19 were ultimately charged with the crime. An acquittal spread allegations of widespread corruption and scared witnesses away. On March 14, 1891, a group of angry New Orleans residents formed a lynch mob and murdered 11 out of the 19 defendants. Eight managed to flee, nine were shot, and two were hanged. As different gangs gained and lost power throughout the years, the American Mafia changed. The Black Hand gangs in the early 1900s, the Five Points Gang in New York City in the 1910s and 1920s, and Al Capone's Syndicate in Chicago in the 1920s were a few of the earliest. The Italian Mafia factions started fighting during Prohibition for exclusive control of lucrative bootlegging networks. They struggled for dominance of bootlegging alongside Jewish and Irish ethnic gangs. By the conclusion of the decade, two Italian organizations were competing for dominance of the nation's criminal underworld. Joe Masseria, the head of the Genovese criminal family, oversaw one gang, while Salvatore Maranzano, who oversaw the Bonanno crime family, oversaw the other. The deadly Castellammarese War, which raged from February 1930 to April 15, 1931, was the result of the rivalry's escalation. When Charles "Lucky" Luciano, Masseria's senior soldier, and Salvatore Maranzano planned to have Masseria assassinated, the battle came to an end. Maranzano eventually rose to prominence as the nation's most powerful Mafia leader, referring to himself as "Boss of Bosses." Maranzano designed the organization's code of conduct, set the conflict resolution processes, and split New York City into five families. Charles "Lucky" Luciano was designated as the leader of the Genovese family, as it eventually came to be known. Maranzano's leadership position would, however, be transitory. Maranzano preferred to exclusively associate with Sicilians and upheld the traditions of the purported "Old World Mafia '' by refusing to cooperate with non-Italians. Younger Italian organized crime figures like Luciano believed that limiting their business dealings to Italians would restrict both the development of their individual careers and the possible expansion of their criminal empires. As long as there was money to be made, these men—known as the "Young Turks''—wanted to deal with Irish and Jewish gangsters. Marazano quickly saw Luciano as a threat and gave the order to kill him. On September 10, 1931, Marazano was murdered by a group of mobsters at his office in the New York Central Building when Luciano learned about the scheme. In order to prevent future Mafia battles, Lucky Luciano formed "The Commission," a coalition of five Mafia families of similar magnitude, with the aid of his lifelong buddy, Meyer Lansky. Vincent Mangano, Tommy Gagliano, Joseph Bonanno, and Joseph Profaci served as the commission's other leaders. After then, this panel made decisions about all organized criminal activity throughout the 1930s. The leaders of the Chicago Outfit and the Five Families of New York City reportedly still make up the Commission. The organized crime groups quickly diversified into new businesses after Prohibition ended in 1933 because they were unable to maintain the high profits they had made throughout the 1920s. These new businesses included labor racketeering through the control of labor unions, construction, loan sharking, extortion, protection rackets, sanitation, transportation, prostitution, and drug trafficking. In Las Vegas, Nevada's legal casinos by the 1950s, numerous Mafia leaders had made legitimate investments and were skimming money before it was recorded. It is assumed that the sum was in the hundreds of millions of dollars. For years, the Mafia operated in secrecy with little opposition from the law because local law enforcement authorities lacked the tools or expertise necessary to successfully confront organized crime perpetrated by a covert organization they were unaware even existed. It wasn't until 1951 that a U.S. Senate investigation concluded that this country was home to a "sinister criminal organization," subsequently known as La Cosa Nostra. Six years later, in the little upstate New York hamlet of Apalachin, The New York State Police discovered a gathering of important La Cosa Nostra officials from all across the nation. Numerous guests were taken into custody. The incident served as the impetus for altering how organized crime is combated by law enforcement. Joe Valachi, the first Mafia member to turn state's evidence in 1963, divulged extensive details about the organization's inner workings and trade secrets. After then, the National Crime Syndicate of the Mafia was aggressively attacked by the Federal Bureau of Investigation. Although the Mafia came under additional pressure as a result, its illegal operations were not significantly reduced. However, the Nevada State Legislature's passage of a measure in 1969 that made it simpler for companies to run casinos caused the Mafia's power in the Las Vegas economy to start to decline. A year later, the RICO Act was approved by the US Congress, giving law enforcement extra power to go after the mafia for its criminal operations. By the start of the 1980s, the FBI had achieved success when it was able to free Las Vegas casinos from Mafia rule and made a concerted effort to weaken the Mafia's grip on labor unions. 23 mafia bosses from all throughout the country were found guilty of violating the RICO statute between 1981 and 1992. By 1990, almost 1000 members of criminal families had been found guilty. While many Mafia organizations around the nation were severely damaged, the most powerful families continued to control crime in their regions. The Mafia has persisted in engaging in a wide range of illicit operations into the twenty-first century, including extortion, government corruption, gambling, infiltration into lawful firms, labor racketeering, loan sharking, and more. Today, Chicago and the Northeast still account for the majority of its operations. La Cosa Nostra's organizational structure has not altered since the 1930s, and Cosa Nostra has operated for more than a century in a variety of guises. Camorra Mafia Now We talked about the American Mob, and we hear about them a lot, so let's talk about the True Italian Mafia, The Camorra. Due to that gang's effect on American organized crime, the term "Mafia" has come to symbolize all forms of organized crime in popular culture. However, that phrase is really the name of the organized criminal gang rooted in Sicily, according to Mafia historian Umberto Santino's study of Mafia and Mafia-type groups in Italy. The 'Ndrangheta, from Calabria, the Sacra Corona Unita, from Apulia, and the Camorra, from Campania, the area that includes the city of Naples, are further "Mafia-type" groups. The history of the Camorra is "particularly discontinuous," according to Santino. Despite having origins that may go as far back as 15th-century Spain, sources like Britannica claim that the organization first rose to prominence in the 19th century. Santino, however, claims that the organization's current form dates back to the late 1950s, when local criminal organizations in Campania started using the term "camorra." In the 1960s, these organizations expanded and became increasingly effective at smuggling cigarettes. In this decade, they also forged advantageous relationships with a number of Neapolitan Mafia factions, which in the 1970s led to the development of profitable black market drug trafficking. However, there is one key distinction between the Cosa Nostra, sometimes known as the Mafia, and the Camorra. While the Mafia has a top-down, pyramidal structure of authority, the Camorra has a more dispersed system of small organizations, or "clans," that hold power. The Camorra has found success with its organizational structure, and as a result, is currently more powerful than the Sicilian Mafia. According to Santino, the Camorra has 7,000 members spread throughout its 145 clans. The Camorra is the most prosperous and feared criminal gang in Italy thanks to its domination over the trafficking in narcotics including cocaine and heroin. The Independent published a story in 2006 about an Italian author named Roberto Saviano who wrote a book that revealed a few more details about the Camorra than the gang would have wanted. He had excellent reason to worry for his life. "This sprawling network of criminal gangs, according to [Saviano]," wrote reporter Peter Popham, "now dwarfs both the original Mafia of Sicily, the 'Ndrangheta and southern Italy's other organized gangs, in numbers, in economic power and in ruthless violence." The New York Times reported that Saviano's book Gomorra was a "literary sensation" that sold more than 500,000 copies, but it also resulted in death threats and compelled him to go into hiding because it depicted gang violence, drug trafficking, child soldiers, and other aspects of the Camorra's business that the gang would prefer to keep hidden from the outside world. Aspects like the rampant government corruption, which causes trash to pile up in the streets car-high, or the fact that the Camorra has killed much more people recently than the Sicilian Mafia and made Campania one of the most deadly regions in Europe. Sicily is where the Mafia that we know and admire today originated. They first appeared at some time in the late 19th century, and over the next 150 years or so, they expanded all over the world and became involved in just about everything. It has long been a mystery how this highly ordered system came to be, but new study from the University of Nottingham suggests that it all began with lemons. Sicily discovered they had the ideal mixture to develop a lucrative crop in the late 1800s. Despite having the greatest concentration of lemon trees in all of Italy, they also faced a particular set of issues. Lemon farmers eventually turned to hiring their own private protection firms to protect their investment and themselves because of factors such as a wealthy upper class that exploited the peasant class to the fullest, a glaring lack of public law enforcement, and a government that really wasn't keeping the peace. Add a few more elements now: Sicily's location on a key Mediterranean trade route, the rapidly expanding citrus industry, and the demand for private security forces to safeguard interests make it the ideal location for the Mafia to establish itself. Don Calo Vizzini was at the head of the Villalba Mafia during World War II, and he may have said it best. He was quoted by the University of Nottingham paper as saying, "In every society there has to be a category of people who straighten things out when situations get complicated. Usually they're functionaries of the state. Where the state is not present, or where it does not have sufficient force, this is done by private individuals." The roots of the Camorra have speculated that it originated from a secret 12th century organization of assassins. The Beati Paoli were a Sicilian group that originated in the 12th century; no one knows why they were given that name, although it's presumably religious in nature. The tale claims that they formed in response to the persecution of the aristocratic class, and the majority of what we know comes from Francesco Maria Emanuele, Marquis of Villabianca. They not only attracted each and everyone to their cause, but they also created a hierarchy akin to a royal court. From there, they set up security services, employed themselves as paid killers, and... well, secrets prevent us from knowing what else. Since they obviously had an underground hideout, we do know that it was accessible through the crypt of a Palermo church. There are even reports that the Camorra had a lot to do with helping the allies sabotage Mussollini in World War 2. Much information was originally written up as German control and sabotage during this time but many years after, with arrests of many members, documents were found that showed that the Camorra and other factions helped screw over Ol' Mussollini. Crips The Crips were only a social group, as one Original Gangster (OG) put it, and by most accounts, he is right (Kontos 99, 2003). While there are numerous uneven areas throughout the turbulent history of the Crips, there are also recurring themes. However, unlike the violent, frequently fatal incidents connected with the Crips, which are frequently portrayed with dramatic exaggeration, the genuine components of the narrative do not make for riveting television. Many OGs and gang members have voiced their shock and disappointment at how the Crips have been portrayed, while still admitting the group's flaws and its final transition from activism to gangsterism. Debra Addie Smith, a close friend of the founder of the Crips, once expressed that she “was wondering when someone was gonna finally tell the real story about the Crips”. The Black Panther movement was being dismantled by the police, who were making "mass arrests, incarcerations, and deaths of black teenagers by the police," which led to the formation of the Crips, a grassroots group mostly made up of African-Americans. The CRIPS (Community Resources for Independent People) emerged in South Central Los Angeles, California, in 1969 with a message of resistance and justice during a period of despair and pessimism within the black community, following the ultimate dissolution of the Black Panther movement. Raymond Washington, a "fearless and strong 5-foot-8 fireplug who liked to fight and detested guns," is credited with founding the gang. He finally distanced himself and was killed as the Crips started using guns and formed a feud with the Bloods. Stanley Tookie Williams met Raymond Lee Washington in 1969, and the two decided to unite their local gang members from the west and east sides of South Central Los Angeles in order to battle neighboring street gangs. Most of the members were 17 years old. Williams however appears to discount the sometimes-cited founding date of 1969 in his memoir, Blue Rage, Black Redemption. In his memoir, Williams also refuted claims that the group was a spin-off of the Black Panther Party or formed for a community agenda, writing that it "depicted a fighting alliance against street gangs—nothing more, nothing less." Washington, who attended Fremont High School, was the leader of the East Side Crips, and Williams, who attended Washington High School, led the West Side Crips. Williams recalled that a blue bandana was first worn by Crips founding member Buddha, as a part of his color-coordinated clothing of blue Levis, a blue shirt, and dark blue suspenders. A blue bandana was worn in tribute to Buddha after he was shot and killed on February 23, 1973. The color then became associated with Crips. By 1978, there were 45 Crip gangs, called sets, in Los Angeles. They were heavily involved in the production of PCP, marijuana and amphetamines. On March 11, 1979, Williams, a member of the Westside Crips, was arrested for four murders and on August 9, 1979, Washington was gunned down. Washington had been against Crip infighting and after his death several Crip sets started fighting against each other. The Crips' leadership was dismantled, prompting a deadly gang war between the Rollin' 60 Neighborhood Crips and Eight Tray Gangster Crips that led nearby Crip sets to choose sides and align themselves with either the Neighborhood Crips or the Gangster Crips, waging large-scale war in South Central and other cities. The East Coast Crips (from East Los Angeles) and the Hoover Crips directly severed their alliance after Washington's death. By 1980, the Crips were in turmoil, warring with the Bloods and against each other. The gang's growth and influence increased significantly in the early 1980s when crack cocaine hit the streets and Crip sets began distributing the drug. Large profits induced many Crips to establish new markets in other cities and states. As a result, Crips membership grew steadily and the street gang was one of the nation's largest by the late 1980s. In 1999, there were at least 600 Crip sets with more than 30,000 members transporting drugs in the United States. Funny side note: As of 2015, the Crips gang consists of between approximately 30,000 and 35,000 members and 800 sets, active in 221 cities and 41 U.S. states. The states with the highest estimated number of Crip sets are California, Texas, Oklahoma, and Missouri. Members typically consist of young African American men, but can be white, Hispanic, Asian, and Pacific Islander. The gang also began to establish a presence in Canada in the early 1990s; Crip sets are active in the Canadian cities of Montreal and Toronto. Bloods The Bloods gang was first established in Los Angeles as a defense against the Crips. The Pirus street gang, which was initially a group of the Crips, split out during an internal gang battle, united with other minor gangs to create the gang that would later become known as the Bloods, which is where the Bloods' origins and their rivalry with the Crips begin. At the time, there were three more Crips sets than Bloods sets. Despite this disparity in numbers, Bloods sets became more aggressive, especially towards rival Crips members, in an effort to demonstrate their dominance. Therefore, it is believed that the Pirus were the original Bloods founders. The gang's concentration changed to drug manufacture during the emergence of crack. The United Blood Nation, a gang that started out on Rikers Island, is frequently associated with blood sets on the East Coast. The George Motchan Detention Center (GMDC), often known as C 73, is located on Rikers Island and is home to the United Blood Nation, also known as the Bloods. Problem offenders were separated from the rest of the jail facilities using GMDC. The Latin Kings were the most prominent and well-organized gang in the NYC jail system before this time. The majority-Hispanic Latin Kings were violently abusing White and occasionally African American prisoners. These African American prisoners created a defense organization they named the United Blood Nation after being organized by some of the most aggressive and charismatic prisoners. This prison group, United Blood Nation, was copying the Bloods street gangs in Los Angeles. Eight initial Blood sets were formed by many of the leaders of this freshly formed prison gang to recruit in their local communities around New York City. By 1996, the Blood street gang had grown to include thousands of members and was becoming one of the most powerful gangs in existence. It also kept up a regular recruiting push. The Bloods were at this point less organized and more vicious than other gangs. Numerous slashings (attacks with a razor blade or knife) that were recorded during robberies were later determined to be Bloods initiations. The Bloods' signature ceremony was the Blood ritual. Bloods found recruits all throughout the East Coast. In addition to members of other races and ethnicities, African Americans make up the majority of the Bloods. Early adolescence to mid-twenties is the average age of members, however some continue to retain leadership roles well into their late twenties and, on occasion, their thirties. Although there is no one person who can be identified as the Bloods' national leader, each individual Bloods set has a hierarchical leadership structure with distinct degrees of membership. Status within a gang is indicated by these membership levels. Each set is managed by a leader, who is often an older person with a longer criminal history. A fixed leader is not chosen; instead, he or she exerts themselves through creating and overseeing the gang's illicit businesses, using their reputation for brutality and violence as well as their own charisma to do so. The majority of the cast members are "soldiers," and they range in age from 16 to 22. Because of their readiness to use violence to win the respect of gang members and to deal with anybody who "disrespects" the set, soldiers have a strong feeling of dedication to their set and are very dangerous. Although they are not full members, "associates" participate in a variety of illegal acts and identify with the gang. If any women are involved in the gang, they are often associate members and are frequently employed by their male counterparts to carry guns, store narcotics, or engage in self-prostitution in order to support their group. The surroundings of a recruit frequently affects recruitment. Bloods actively seek for school-age African Americans in particularly impoverished regions. Youth might find security and a sense of belonging by joining a gang. Economically deprived children who observe the trappings of gang life—gold jewelry, cash, pricey sportswear—can likewise experience instant satisfaction. Based on how long a person has been a part of a certain set, blood sets have an informal hierarchy of levels. The ranks are only a symbol of respect for individuals who have been a part of the set the longest and have survived the longest; they do not indicate leadership or domination over the set. Bloods of lesser ranks are not subject to those in positions of authority. Bloods of lesser status frequently refer to Bloods of higher rank as "Big Homies." They also call one another "relatives." Once a person joins a Blood set, they cannot quit the set or flip (move to another set) for the rest of their lives. Members of the Bloods frequently refer to themselves as dawgs or ballers, HKs (an initialism for Hoover-Killer), CKs (an initialism for Crip-Killer), and MOBs (an initialism for Member of Bloods) (meaning drug dealers). Contrary to popular belief, Bloods & Crips are typically friendly amongst sets. Although it is against the law, bloods sometimes engage in civil war with one another. For example, the deuce 2x Crips and tray 3x Crips are at war, and they frequently work with Crip sets to eliminate their fellow blood competitors. The many gang indicators used by Bloods members to distinguish themselves from other gangs include colors, attire, emblems, tattoos, jewelry, graffiti, language, and hand signals. Red is the gang's primary color. They like donning athletic attire, such as team coats that display their gang's colors. San Francisco 49ers, Miami Heat, Atlanta Hawks, Houston Rockets, Boston Red Sox, St. Louis Cardinals, Cincinnati Reds, Portland Trailblazers, Cleveland Indians, Philadelphia Phillies, Los Angeles Clippers, New Jersey Devils, Philadelphia 76ers, and Chicago Bulls are a few of their favorite clubs. The most commonly used Bloods symbols include the number “5,” the five pointed star, and the five pointed crown. Despite common misconception Bloods are not a people nation (with the exception of a few) but they will however tie flags with the people for defense or mutually such as how the Crips & BGDs consider themselves cousins. These symbols may be seen in the tattoos, jewelry, and clothing that gang members wear as well as in gang graffiti, which is used by the Bloods to mark their territory. Such graffiti can include gang names, nicknames, declaration of loyalty, threats against rival gangs, or a description of criminal acts in which the gang has been involved. Bloods graffiti might also include the word “Piru” which refers to the fact that the first known Bloods gang was formed by individuals from Piru Street in Compton, California. Yakuza During the Tokugawa Shogunate (1603–1868), two distinct groups of outcasts gave rise to the yakuza. The tekiya were the first of such groups; they were nomadic peddlers who moved from village to village selling cheap things at fairs and markets. Many tekiya belonged to the burakumin social class, which was essentially underneath the four-tiered Japanese feudal social order and consisted of misfits or "non-humans." The tekiya started forming close-knit gangs in the early 1700s under the direction of bosses and underbosses. The tekiya began to engage in customary organized crime operations including turf battles and protection rackets after being strengthened by fugitives from the upper classes. In keeping with a long-standing custom, tekiya frequently provided security for Shinto festivals and, in exchange for payment for protection, assigned stalls at the associated fairs. Between 1735 and 1749, the shogun's government appointed oyabun, or officially recognized leaders, in an effort to quell gang conflicts among various tekiya factions and lessen the amount of fraud they engaged in. The oyabun was given the privilege of using a surname and carrying a sword, which was previously reserved for samurai. The term "oyabun," which refers to the bosses' roles as the leaders of their tekiya families, literally means "foster parent." The bakuto, or gamblers, were the second social group that gave rise to the yakuza. During the Tokugawa era, gambling was outright prohibited and is still outlawed in Japan today. The bakuto hit the highways and preyed on gullible prey using hanafuda card games or dice games. They frequently adorned their bodies with vibrant tattoos, which gave rise to the practice of full-body tattooing among modern yakuza. The bakuto naturally expanded from their primary line of work as gamblers into lending shady business and other illicit pursuits. Depending on how they make the majority of their money, certain yakuza groups may still refer to themselves as tekiya or bakuto. They still use the rites that were a component of the initiation ceremonies of the older organizations. Yakuza gangs have seen a rise in prominence since the end of World War II following a decline during the conflict. More than 102,000 yakuza members in 2,500 different families were reported to be employed in Japan and overseas by the Japanese government in 2007. Despite the burakumin being officially exempt from discrimination since 1861, many gang members today are descended from that marginalized group. Others are ethnic Koreans, who are also subjected to a great deal of prejudice in Japanese society. The distinctive characteristics of modern yakuza culture bear traces of the gangs' antecedents. For instance, a large number of yakuza have full-body tattoos that were applied with conventional bamboo or steel needles as opposed to sophisticated tattooing guns. Even the genitalia may be tattooed, which is a very unpleasant ritual. Although they typically wear long sleeves in public, the yakuza members frequently take their shirts off while playing cards with one other and show off their body art as a reference to the bakuto customs. The practice of yubitsume, or cutting off the little finger's joint, is another aspect of yakuza culture. When a yakuza member disobeys or otherwise offends his boss, he will perform a yubitsume as an apology. The offender provides the boss with the top joint of his left pinkie finger, which he has amputated. Subsequent offenses result in the loss of other finger joints. This practice dates back to the Tokugawa era; the gangster's sword grip is weakened by the loss of finger joints, theoretically making him more reliant on the group as a whole for defense. To blend in, many yakuza members wear prosthetic fingertips today. The three biggest yakuza organizations currently in existence are the Sumiyoshi-kai, which started in Osaka and has about 20,000 members, the Yamaguchi-gumi, centered in Kobe, with 15,000 members, and the Inagawa-kai, located in Tokyo and Yokohama, with 20,000 members. The gangs engage in illegal activities such the trafficking of people and goods, the exportation of weapons, and the smuggling of illegal drugs. They do, however, also own a sizable amount of stock in well-established companies, and some of them are well-connected to the Japanese financial, banking, and real estate industries. It's interesting to note that the Yamaguchi-gumi were the first to assist victims in the gang's hometown after the tragic Kobe earthquake of January 17, 1995. Similar to this, many yakuza organizations delivered truckloads of goods to the afflicted area following the earthquake and tsunami of 2011. The yakuza also has the strange benefit of suppressing small-time criminals. Because small-fry thieves don't intrude on yakuza turf, Kobe and Osaka, with their strong yakuza syndicates, are among the safest cities in an overall safe country. The Japanese government has clamped down on the gangs in recent decades despite these unexpected social benefits of the yakuza. A strong new anti-racketeering law known as the Act for Prevention of Unlawful Activities by Criminal Gang Members was passed in March 1995. All of the listed businesses with ties to the yakuza were removed from the Osaka Securities Exchange in 2008. Yakuza bosses have been detained by authorities since 2009, and businesses that support the gangs have been closed down. Even though the police are currently working very hard to quell yakuza activities in Japan, it appears improbable that the syndicates would completely vanish. After all, they have endured for more than 300 years and are intricately linked to many facets of Japanese society and culture. Mara Salvatrucha(MS-13) La Mara Salvatrucha, also referred to as MS-13, is a ruthless, inhumane street gang. As many as 40 states in the United States are now home to MS-13 members who commit murder, rape, maiming, and terror. Legendary tales exist of their heinous crimes. No one contests the veracity of these statements. MS-13, like many street gangs, actually takes pride in its well-deserved image. The U.S. Department of Justice claims that the group's motto is "kill, rape, control." If you believe President Donald Trump and others, America's broken immigration system is to blame for MS-13. The belief is that the United States will be a lot safer if it can stop MS-13 gang members from committing all of their mayhem, deport them, and stop them from crossing the border. Unfortunately, things don't work that way. "Attention to gangs is valid. About 13 percent of the homicides in this country are gang related. That's far more homicides than from mass shootings or terrorism," David Pyrooz, a sociologist at the University of Colorado who specializes in gangs and criminal networks, says. "But let's remember this. The maximum number of homicides associated with MS-13 in a given year — gang-related homicides — is about 2 percent of the total ... gang-related homicides in the United States. That is, I hate to use this language, but that is in many ways a drop in the bucket when it comes to gang activity." "MS-13 is sort of the perfect boogeyman," Pyrooz says. "They are the moral panic; the connection to immigration, the connection to Latinos, and then the heinous violence, makes it so they can function as this evil boogeyman." It's frequently forgotten in discussions of MS-13 that the organization didn't start out in Latin America and then storm the border to wreak havoc on the American way of life. The gang was founded in the United States in the 1970s. El Salvadoran immigrants went to Los Angeles in an effort to escape a devastating civil conflict. There, they lived in areas of the city that were already under the influence of other gangs, used marijuana, and listened to heavy metal music. La Mara Salvatrucha was created when the newcomers came together to socialize and to defend themselves from other groups. A brief explanation of the group name is as follows: In El Salvador, the word for "gang" is "mara." Here is an explanation of "Salvatrucha" and the subsequent 13 (again, from the DOJ): Salvatrucha is a slang term for "alert," "watch out," or "cunning," and it combines the terms "Salva," which stands for "Salvadoran," and "trucha." The "13" stands for the 13th letter of the alphabet, or "M," signifying the group's ties to the Mexican Mafia, an organization that operates inside prisons. Police started to crack down as the new gang confronted more established organizations in Los Angeles and linked up with other gangs (including the Mexican Mafia), deporting some members to El Salvador, where civil instability remained rife. However, some of those MS-13 members returned to the United States in the 1980s, and others from El Salvador joined them. However, it seems unlikely that there was a premeditated influx of gang members from Latin America into the country. "Criminal migration is real," according to "MS13 in the Americas: How the World's Most Notorious Gang Defies Logic, Resists Destruction," a report by The Center for Latin American & Latino Studies at American University in Washington D.C., and Insight Crime, a foundation that studies organized crime in Latin America and the Caribbean. "But this does not appear to be part of a master plan, nor is it coordinated from some central headquarters. Gang members appear to move in the same patterns as the rest of the population, and many of them move to escape the gang and the violence associated with it." Currently, MS-13 claims to have 10,000 members in the United States and 30,000 members worldwide. Thus, it ranks among the largest gangs in the entire world. The group is the first and only street gang to be listed as a global criminal organization by the American government. Despite its size, MS-13 does not have a particularly significant criminal presence in the United States when compared to the total number of gang members in the nation. The National Gang Intelligence Center estimates that there are 1.4 million gang members nationally, and MS-13 is just one of the 33,000 gangs that the FBI has identified. "What's interesting about them, what makes them different from other groups — partly in response to what the president has been tweeting and talking about them" Pyrooz says, "we can't think of an example in recent history of a single group that has attracted such attention on a national level." According to news reports and those who have investigated the MS-13 gang, its members engage in money laundering, prostitution, drug trafficking, racketeering, and other illicit activities. They are extremely brutal in how they do their street business. The group has been implicated in numerous violent assaults, kidnappings, rapes, and most infamously, some horrifying murders. "Gang violence is far more lethal than what it was four or five decades ago," Pyrooz says. From "MS-13 in the Americas": "Violence is a major part of the glue that binds the MS-13. It is part of every stage of an MS-13 member's life: Potential members commit violent acts to be considered for membership and ultimately to gain entry; they are then beaten into the gang in a ritual that has left more than one permanently scarred; they move up the gang ladder by 'putting in the work' and showing 'commitment,' euphemisms for committing violent acts in the name of the gang." According to the Washington Post, up to 10 MS-13 members lured a guy into a park in Maryland in 2017 before stabbing him more than 100 times, beheading him, and chopping out his heart. In vengeance for her boyfriend's murder, an 18-year-old Virginia lady admitted to taking part in the killing of a 15-year-old girl. The 18-year-old killed the younger girl by stabbing her 13 times and recorded it to show MS-13 leaders. "It's hard to say that the attention is not undue or not deserved," Pyrooz says. "But it's hard to be able to focus specifically on them without paying more attention to what the problem of gang activity is in the United States as a whole." The 25 Best Gang Movies of All Time - IMDb
Patrick Desrumaux, Managing Director van het Belgische modelabel Xandres, heeft al heel wat op zijn palmares staan. Na twee jaar lang als Researcher te hebben gewerkt bij de Vlerick Management School, ging hij aan de slag als Commercieel Directeur bij E5 mode, een functie die hij maar liefst 7 jaar bekleed heeft. In de jaren daarop werkte hij als Sales & Marketing Manager bij CKS, en nadien als hun Algemeen Directeur. Bovendien richtte hij ook zijn eigen merk Besuite op. Met andere woorden: iemand met een ervaring om u tegen te zeggen in de kledingsector. En in zijn vrije tijd? Dan is hij bezig met ‘permanent studeren' zoals hij zelf zegt, of brengt hij tijd door met zijn twee tieners van 14 en 16 jaar. Xandres is een Oost-Vlaams modebedrijf dat ontstond in 1968. Het merk kende zijn oorsprong al in 1927, en stond oorspronkelijk vooral bekend om zijn werkbroeken en -kledij. Intussen ontpopte het zich tot een luxueus en tijdloos modemerk. Wanneer het merk in de zomer van 2016 werd overgekocht door Damartex Group, was het Patrick Desrumaux die aan het hoofd ervan kwam te staan. Xandres is momenteel in volle ontwikkeling om een nog inclusiever en duurzamer merk te worden, en biedt collecties aan van maat 34 tot maat 56. Diversiteit is hun schoonheidsideaal, en ze willen elke vrouw hullen in de perfecte pasvorm, stof en uitvoering. Romy Schlimbach, aka Romy Curvy, is plussize model, Dove Selflove Ambassador van 2022, schrijfster van de Self Confidence Column in Flair, en baatte daarnaast ook een eigen pop-upstore uit in Mechelen: Romy Curvy zit niet stil! Als body positivity activiste, volgt ze bovendien de plussize community op de voet. Je kunt haar volgen via @Romycurvy op Instagram.
It's back-to-school season, and with that comes IEPs, IPRC, 504s, and education plans! If the terms or process are confusing and frustrating, we have covered you in this week's podcast with Mark Courtepatte – one of the most popular Insider Experts in our CKS Coaching Program. But you don't have to be in the program now to hear his expertise!We talk about how Mark met Savanna, his partner who has FASD, how they became involved with the Hamilton Parents and Caregivers Support group that he co-chair, and how his interest in the education sector developed.This episode is full of insight on how to work collaboratively with teachers and the school board. Mark is just as comfortable talking to the Minister of Children and Community Services as he is too overwhelmed by caregivers or children with FASD. You will find out why he thinks 99% of IEPs are not worth the paper they are written and gives you some concrete steps to follow from being confused and not sure how to proceed to become the confident advocate for your child. He provides some suggested rebuttals to resistance and gives you a gauge to know if the plan is working. You are going to find out why his workshops are one of the most popular in our CKS program.Be sure to check out the show notes for a link to our blog where you can find his awesome support group website.Show Notes: Check out our blog for all the links at FASD Success.Smells Like HumansLike spending time with funny friends talking about curious human behavior. Listen on: Apple Podcasts SpotifySupport the show
https://go.dok.community/slack https://dok.community/ ABSTRACT OF THE TALK During my first talk for DoK community I want to walk you through the world of NoSQL database MongoDB and Kubernetes Operators - Community Edition, Enterprise Edition (MongoDB and Ops Manager on K8s), and Atlas operator, highlight the most important capabilities, talk about use cases and challenges, the theory will be mixed with a live demos! BIO I'm a SRE / NoSQL / DevOps professional. I hold CKA, CKAD, CKS, also I'm MongoDB Certified DBA and MongoDB Champion. I have experience with multiple cloud providers, Kubernetes, different types of K8s operators (Strimzi, RabbitMQ Cluster Operator), but especially MongoDB K8s Operator. I also work with KEDA. Since 2017, I have been a speaker at MongoDB conferences all around the world (USA, China, Europe). KEY TAKE-AWAYS FROM THE TALK I would like to share the best practices of running NoSQL database - MongoDB on Kubernetes also I want to show how to manage Atlas (MongoDB cloud) via K8s operator https://www.mongodb.com/developer/community-champions/arkadiusz-borucki/
Ann Claes is de CEO van modebedrijf JBC. Ze leidt het bedrijf samen met haar broer Bart. Het heet niet meer JBC, het heet Claes Retail Group, en bevat behalve JBC ook Mayerline en CKS, wat ze overnamen in volle coronacrisis. Het hoofdkwartier van het bedrijf is in Houthalen, en daar hadden we afgesproken voor dit gesprek. In een zaaltje waar niet alleen een tafel en stoelen staan, maar ook een kleedhokje. Ann Claes vertelt over het managementboek dat ze na vele jaren opnieuw las en zo goed vond dat ze het onmiddellijk gaat beginnen toepassen in haar bedrijf. Over hoe het is om als bedrijfsleider bovenaan te staan, en niemand boven je te hebben. Over het familiecharter van het bedrijf - ze hebben een familiecharter. Over je best willen doen, én over goed willen doen. En over hoe Dimitri Verhulst haar met een boek terugbracht naar haar kindertijd. Alle boeken en auteurs uit deze aflevering vind je in de shownotes op wimoosterlinck.be De drie boeken van Ann Claes zijn: 1. Steven Covey: De zeven eigenschappen van effectief leiderschap 2. Annelies Smolders: Start to sleep 3. Dimitri Verhulst: De helaasheid der dingen
Life as an FASD Caregiver is challenging enough – but what about when you have to leave everything you have ever known, first to seek immediate safety, then as a refugee to another country and then apply as a refugee yet again – all in the space of three months, while raising two daughters, one with FASD. We first met Olga and Serhii Bolshova, a family I interviewed days after Russia invaded Ukraine in Episode 97: Olga and Serhii: An FASD Family on the Front Lines in Ukraine. Olga is an alumnus of our CKS! Caregiver Kick-start Coaching Program and was beginning her journey to help build an FASD community in her homeland when war was declared. You may remember on the night they were to flee from their home, Olga had Serhii and the girls waiting in the car as she wrapped up an FASD training session on Zoom! It's been a few months and their adventures continue. Many of you wondered how they are, so once I found out they were in Ontario, I knew I had to take a drive down to see them. Check out the episode to find out about life in a refugee camp in Poland, how they have been welcomed into Canada and what their next steps are. Show Notes: Check out our blog for all the links at FASD Success Smells Like HumansLike spending time with funny friends talking about curious human behavior. Listen on: Apple Podcasts SpotifySupport the show
At the May 25, 2022, Board of Supervisors (BOS) meeting, there was a lively debate regarding whether or not to send the 5G wireless JMZO amendment back to the Joint Zoning Council (JZC) with the changes, corrections, additions suggested by the CKS, the Township Planner. There was a disagreement as to whether and WHEN other changes such as those suggested by Mr. Andrew Campanelli, ESQ. should be passed on to the JZC. In the end, the supervisors agreed by a 4-1 vote to table the motion until further discussion about other changes can be had. Jerry Schenckman, JZC Solicitor, agreed to work with supervisors to hammer out suggested changes to bring before the BOS at its next public meeting.
Gościnią najnowszego, 36. odcinka podcastu "Hallo Haller" była Karolina Zdrodowska – dyrektorka koordynatorka ds. przedsiębiorczości i dialogu społecznego. Zarządza i koordynuje pracę następujących komórek organizacyjnych Urzędu m.st. Warszawy: Biura Rozwoju Gospodarczego (RG) i Centrum Komunikacji Społecznej (CKS). W najnowszym odcinku podcastu "Hallo Haller" prowadząca Dorota Haller zaprosiła do rozmowy Karolinę Zdrodowską, która jest polityczką, dyrektorką koordynatorką ds. przedsiębiorczości i dialogu społecznego oraz bliską współpracowniczką prezydenta Warszawy, Rafała Trzaskowskiego. Na co dzień pracuje w stołecznym ratuszu, gdzie zajmuje się zarządzaniem i koordynowaniem działań następujących komórek organizacyjnych Urzędu m.st. Warszawy: Biura Rozwoju Gospodarczego (RG) oraz Centrum Komunikacji Społecznej (CKS). Na wstępie rozmowy gospodyni podcastu zauważa, że Zdrodowska jest z wykształcenia architektką. Haller dopytała ją o odczucia, wiążące się z decyzją o zmianie drogi zawodowej, którą podjęła kilka lat temu. — Tak naprawdę architektka to jest mój drugi zawód, bo na początku byłam jeszcze nauczycielką języka angielskiego — zdradziła gościni. Podkreśliła, że dużym przełomem było dla niej przejście do samorządu
After the U.S. dropped an atomic bomb on Hiroshima in 1945, nations around the world began thinking about acquiring nuclear weapons of their own. Among them was China, then ruled by supreme leader Chiang Kai-shek. The Nationalists' retreat to Taiwan interrupted those early ambitions, but when the PRC successfully detonated a nuclear device in 1964, CKS stepped up efforts to develop nukes. This secret program continued after the death of Chiang Kai-shek in 1975 and came surprisingly close to success. Taiwan, however, would not end up joining the Atomic Club. Here's the story of how that happened:
Siden Espen har tatt vinterferie har Christian fått inn Thomas Lone som supervikar. Vi skal innom resultatene til Flyr, Norwegian og SAS - og selvsagt SAS Forward. Ellers skal vi også innom brannslukningsfly og fem-motors A380. Velkommen ombord på flight 193 som ble spilt inn 22.02.2022 Ulykkesflight 193: National Airlines 193 Vraket av "Donna" heves. Selv om flyet ikke ble så skadet av landingen i sjøen, ble det avskrevet på grunn av korrosjon etter oppholdet i saltvann Tara Air 193 Lockheed L-193 Constellation II AKTUELT: Flyr Q4-resultat Norwegian Q4-resultat SAS Q1-resultat og SAS Forward ST Aerospace skal konvertere 15 757-200 til brannslukningsfly Airbus og CFM sammen om hydrogenfly - skal teste på en A380 Airbus A380 med en femte motor - som skal teste hydrogen som drivstoff UKENS ANBEFALING: Følg med på sikkerhetsgjennomgangen når du er ute og flyr (en av CKs favoritter) https://www.youtube.com/watch?v=z1A5BtqsaPM
Tech News & AMA #15 with our community members Abdelfettah, Kawtar and Youssef. During this episode, we discuss the latest Tech News, and we answer audience questions about programming, community, new technologies, and much more. Guests Kawtar Choubari Youssef Benadda Abdelfettah Sghiouar Notes 0:00:00 - Introduction 0:04:00 - Kawtar experience and learning process during last year. 0:10:32 - Time management advice for beginners. 0:21:00 - Youssef experience with Notion apps and doing profitable projects. 0:33:00 - Career advice about PFE internship on salesforce and its future for a developer. 0:38:00 - Can a developer combine between Dev and DevOps? 0:41:00 - K8s certifications: More valuable ones for a career (CNCK, CKAD, CKA, or CKS). 0:44:00 - Does the school and diploma in IT matter? 0:55:00 - Do developers need to learn about marketing in addition to programming? 1:01:00 - MoroccoTech 1:08:00 - First GDE in Morocco. 1:13:00 - faker.js story 1:32:00 - Giveaway. 1:33:00 - Tips on obtaining many certificates. 1:36:00 - Best practices to measure code quality as a junior developer? 1:51:10 - GeeksBlabla Picks. 1:59:00 - Wrap up & Goodbye Picks Atomic Habit How to Get Rich Storytel The Ministry for the Future Save to Notion Links The Dark side of open source, What really happened to faker.js MoroccoTech With Zouheir Lakhdissi Google Developer Expert GDE program application form Morocco's Chari valued at $100M Prepared and Presented by Youssouf El Azizi
As a research scientist in the health care field, Ngaire thought she knew everything, but now understands how little she knew. With three girls on the Spectrum, it felt like WW3 in the home with rages, outbursts, and mental health concerns. Combining what she learned in the CKS Coaching Program with her research background, she set goals and applied a scientific analysis to measure progress. Her unrealistic expectations have been shelved and they are celebrating a year of no physical aggression, thanks to the education, coaching and support she has received in the CKS. Show Notes: Want to learn more about FASD, find support and expert advice? Registration closes Friday, October 29, 2021: The CKS Coaching Program or catch up in the free: CKS Workshop Check out our blog for all the links at FASD Success Support the show
Previous guests have included moms and dads, but this is the first time we've had a couple appear together to talk about their journey as FASD Caregivers. I couldn't think of a better couple than Chandra and Jordan as the first. Chandra and Jordan are parents to 6 children – two with an FASD diagnosis and one suspected. Like Angelene Bruce, our conversation was not intended to be a podcast. It was for a case study for our upcoming CKS workshop. Like Angelene, their story is filled with great lessons that will benefit many.Chandra and Jordan are always a favourite on our Coaching Calls. I am excited for you to listen to what they have learned. You can try us out with the Caregiver Kickstart Workshop next week. The link is in the Show Notes.I do not doubt that with knowledge, understanding and support you too can achieve great things for yourself, your family, and your kids.Visit our blog for more information: The FASD Success ShowWant to learn more about FASD? Sign up for our free CKS Workshop Support the show (https://www.buymeacoffee.com/FASDSUCCESS)
Continuing with our series, in this video will the cover the "Workloads and Scheduling" domain for the Certified Kubernetes Administrator exam. In episode 4, we are going to be talking with Walid Shaari (@walidshaar) about Workloads and Scheduling. Walid is a cloud-native advocate #RedHatAccelerator, and #AWSContainerHero. He also holds the CKA, CKAD, and CKS certifications which can give you an overview of the experience he has within Kubernetes. We will see the different topics within this domain, practice with some questions and even tricks that will help you within the exam. Resources: https://kubernetes.io/docs/reference/kubectl/cheatsheet/ https://github.com/walidshaari/Kubernetes-Certified-Administrator https://github.com/walidshaari/vmug-cka
Queen Kate @CogirlWIworld, and one of my new favorites, Daniel Kotnik, aka.. Double D, aka... Danny Dimes, Packer Podcast OG over @packadaypodcast & Lombardi's Bar @gameonwi, just fills the air with concise common sense and just great talk, joined the E-Squared Brigade today and we rapped life, Kate's San Fran tailgating, her No F&CKS given for shitty fans, Pittsburgh tailgating with the Twitter Crew, and we find out these Kids like Spotted Cow a bit, huh? Green Bay Packers Podcast!!! Eric and Eric - Couple 1-2 Northern Wisconsin Boys, bleed Green and Yellow, both might say something we regret! SUPPORT OUR SPONSOR: www.tuliptreegardensco.com Check us out on all socials you dig below! https://linktr.ee/AcmeArmy https://www.youtube.com/channel/UCflsTCMM7xu-txkN-PTSQGQ https://podcasts.apple.com/us/podcast/acme-army-podcast/id1532625760 https://open.spotify.com/show/42fewGyqrFJcSLxzk5VaHL?si=SJBAGsBaQY2sjdXLN7nriA https://PeterPrinceMusic.com THANK YOU PETER, for the Greatest Music around!!! Check out Peter, Today! --- Send in a voice message: https://anchor.fm/acmearmy/message Support this podcast: https://anchor.fm/acmearmy/support
Tonight will be a continuation of our Certified Kubernetes Administrator series, where we are covering the major domains of the exam. In episode 3, we are going to be talking with Tyler Hatton (@tlrhtn) about Cluster Configuration. Tyler is an automation SME and focuses on assisting traditional IT organizations to adopt SRE/DevOps principles. He also holds the CKA, CKAD, and CKS certifications, so you are in amazing hands for this talk! Stay tuned for tips and tricks for the exam, a way to spin up Kubernetes clusters quickly and easily for studying, and an overview of managing a K8S cluster with kubectl, RBAC, namespaces, and more. Resources: https://twitter.com/tlrhtn https://www.linkedin.com/in/tyler-hatton/ https://katacoda.com/ https://kubernetes.io/docs/reference/kubectl/cheatsheet/ https://kubernetes.io/releases/version-skew-policy/ https://kubernetes.io/docs/tasks/administer-cluster/kubeadm/kubeadm-upgrade/ https://www.udemy.com/course/certified-kubernetes-administrator-with-practice-tests/ https://killer.sh/cka
Workplace MVP: Drew Sewell, CKS Packaging Drew Sewell, COO of CKS Packaging, experienced a compelling call to confront the sources of the problems of drug dealing, prostitution, and crime affecting the area near his company’s Atlanta headquarters. That calling led to the successful development of second chance hiring program for formerly incarcerated individuals at CKS […] The post Workplace MVP: Drew Sewell, CKS Packaging appeared first on Business RadioX ®.
ETV Bharat Karnataka news in kannada for May 4 2021 12pm is about Inquiry officer visits Chamarajanagar district hospital, Vidhan Sabha former speaker Ramesh Kumar writes letter to Karnataka CM over Chamarajanagar oxygen tragedy, India's total covid cases tally crosses 2 crore mark with 3,57,229 new cases, IPL 2021- CSK vs RR match in trouble as CKS's bowling coach tested positive for Covid and several other news, for more live news download Etv Bharat Download ETV Bharat on App store – https://apps.apple.com/in/app/etv-bharat/id1453416186 Play Store – https://play.google.com/store/apps/details?id=com.etvbharat.android Or watch us live on – www.etvbharat.com ETV Bharat is d Division of Ushodaya Enterprises Pvt. Ltd. , is a comprehensive digital national news platform conceived to deliver seamless news and information services, using video-centric Mobile App and Web Portals. It is first-of-its kind offering in India in terms of diversity and depth, dedicated journalists network, reach of 24 states with services in 13 languages i.e.– Hindi, Urdu, Telugu, Tamil, Kannada, Malayalam, Gujarati, Marathi, Bengali, Punjabi, Assamese, Odia and English. ETV Bharat is the latest initiative of the five-decade old multi-dimensional Ramoji Group. The Group's highly successful media endeavors include : Eenadu - one of the largely circulated language dailies in the country , and ETV Network with Telugu general entertainment, infotainment and news channels. With a strong lineage of the most trusted media house, ETV Bharat would draw on its strengths of decades' long experience and innovation. ETV Bharat will combine the new technologies of mobile and digital media to engage news and information seekers in a new connected world. It will be driven by well-established news gathering setup, technology specialists and other professionals.
In this episode, hosts Alan Cammack of Canyon River Instruction and Ryan Wiegman (@digitallcowboy), interview Fred Morrison from CKS Main Street. Fred gives us his speculation on the new Dagger Code and the just-released Pyranha Scorch. We also talk about the King and Queen of the Arkansas community paddle that Fred organizes with a few other folks. Finally, we give our prediction on high flows on the Arkansas this year and what boats CKS will have in stock.
An interview with Aaron Pott from Denver’s “House of Welcome and Mission.” Malcolm Schluenderfritz and Peter Land interview Aaron Pott, who lives in a small Denver-area Christian intentional community, Casa Karibu Sze-Ming. Aaron talks about the origin, history, mission, spirituality, and structure of his community; the “home liturgies” that help glue the community together; the ups and downs of community life; raising children in a community setting; sharing burdens with others; the financial benefits of community; ecumenism; the other communities he has experienced; the balance between consensus and leadership; the dangers of idealism and overly-high expectations; not expecting a community to meet all of one’s needs; staying connected to a wider community; and the importance of hospitality. Peter Land is able to talk about his experience staying at Casa Karibu as a pilgrim traveling through Denver. (Image shows some of the CKS members in 2019. Courtesy of Aaron Pott)
Einundzwanzig. Sieben. Drei. Diese Zahlen kommen immer und immer wieder vor in der Mordserie des Countdown-Killers, und zwar so oft, dass es auffällt, wenn sie es nicht tun. Es war schon immer merkwürdig, dass er seine Mordserie mit einem zwanzigjährigen Opfer begonnen haben soll, wenn er doch von der Zahl einundzwanzig besessen ist. Endlich stößt Elle auf eine Spur, die sie zu CKs allererstem Opfer führt …
Covid cluster grows. Taiwan's population drops. Most are satisfied with job, gender equality. Man eggs CKS statue. Government Chinese IT kit to go. International pressure over automotive chips. Flying squirrel, Yuhan launched into space. PRC belligerence rises. Hsiao Bi-khim quarantined.
Covid cluster grows. Taiwan's population drops. Most are satisfied with job, gender equality. Man eggs CKS statue. Government Chinese IT kit to go. International pressure over automotive chips. Flying squirrel, Yuhan launched into space. PRC belligerence rises. Hsiao Bi-khim quarantined.
Today's episode comes with a trigger warning. Also, if you play our episodes while your children are in the room, I suggest you wear headphones or listen when alone because we talk openly about challenging behaviours, addictions, mental health, truancy, running away and suicide. My conversation with Megan Tucker about Harm Reduction may also trigger reactions to long-held beliefs or value clashes – but if you feel like you are at the end of your proverbial rope with any of the above, the Harm Reduction Model is a shift in thinking and supporting that can turn things around. I have known my guest for many years, having attended conferences as presenters and worked with Megan in my CKS program. She is the Training Coordinator, as well as a Prevention Conversation Facilitator at the Lakeland Centre for FASD (Alberta). She studied Humanities at the University of Alberta. Megan has worked at the Lakeland Centre for almost 10 years in multiple capacities. She created and implemented the Transition to Adulthood Program currently in place at the Centre and was also Children's Coordinator as a part of the Centre's Post Diagnostic Services. She provides FASD training in the Lakeland region as well as at conferences outside of the region. If you haven't heard of harm reduction or harm minimization, it refers to policies or programs designed to lessen the negative social and/or physical consequences associated with both legal and illegal human behaviour. This is a model that is now being adopted to help people who support people with FASD. So do you need to implement harm reduction? You might if you feel you have tried “everything” and “nothing” has worked, and you view your child's or client's behaviours as purposeful and willful. Are you constantly frustrated and mad? If so, it is unlikely you are providing the supports they need and harm reduction might be what you need. “We get so angry at the behaviour and we misinterpret it and then we disconnect and that's when our child (teen, adult) goes to look for connection elsewhere. What does the brain need? Connection. We all need a connection. We need to be cared about. We need to know that we are good and valuable people."Megan and I explore what we need to understand about individuals with FASD, as well as: What the root of harm reduction is (and isn't). The brain domains and inconsistencies that make individuals vulnerable.Two keys to the harm reduction model. Harm reduction is unorthodox, as it goes against what we were taught or how we are used to parenting. It can feel like it won't work, or you are giving in. You need to ask yourself, what part are you playing in the behaviour? And you need to understand the brain basis behind the behaviour. But the more you can make sense of it, the better off everyone will be.This is a difficult topic for many caregivers. There is no judgement here and like with anything about FASD, you don't know what you don't know. So, we offer different ways to provide support to ensure success for caregivers and individuals on the Spectrum. Harm reduction is peeling back the layers to find the disconnect. Figuring out how we can reconnect and show up for our kids, to let them know they are good and valuable, so they don't find that connection somewhere else. If you want to learn more about Megan's work, and the Lakeland Centre for FASD, she is hosting monthly Lunch and Chats on Facebook (link in Show Notes) to explore different topics. Let me know what you think about this topic. Is it something you've heard of? Use? Found success with? Show Notes:Lakeland Centre for FASD Support the show
# Podcast S02-E01: Up and runnning... Amazon se esta pasando? - Conducido por @_marKox, @domix ## Revisión de las noticias - [Amazon: NOT OK - why we had to change Elastic licensing](https://www.elastic.co/blog/why-license-change-AWS) - [Certified Kubernetes Security Specialist (CKS)](https://www.cncf.io/certification/cks/) - [Kubernetes Security Essentials Course Now Available](https://www.cncf.io/blog/2021/01/08/kubernetes-security-essentials-course-now-available/) - [Enroll in CKS Prep Skool by StackRox](https://security.stackrox.com/CKS.html) - [AWS re:Invent 2020 – Top Announcements](https://aws.amazon.com/blogs/aws/aws-reinvent-announcements-2020/) - [Announcing HashiCorp Waypoint 0.2.0](https://www.hashicorp.com/blog/announcing-hashicorp-waypoint-0-2-0) - [Announcing HashiCorp Boundary](https://www.hashicorp.com/blog/hashicorp-boundary) - [Announcing CDK for Terraform 0.1](https://www.hashicorp.com/blog/announcing-cdk-for-terraform-0-1) - [Shifting Modes: Creating a Program to Support Sustained Resilience](https://www.infoq.com/articles/series-enhancing-resilience-2/) - [97 things every SRE should know - Part 01](https://www.unixdaemon.net/sysadmin/97-things-every-sre-01/) ## Referencias y Recursos - [Cloud Native Computing Foundation (CNCF) annual report for 2020](https://www.cncf.io/wp-content/uploads/2021/01/CNCF-Annual-Report-2020.pdf) ## Repos chingones de código - [kube-linter](https://github.com/stackrox/kube-linter) ### Créditos de música Music by Scott Buckley – www.scottbuckley.com.au
Bart Claes is CEO van het kledingbedrijf 'CRG' (Claes Retail Group), bekend van de merken JBC en Mayerline. Van de groep FNG nam hij recent ook het modemerk CKS en de kindermerken Fred & Ginger en Baker Bridge over. Bart is een dynamische merkenbouwer en is tevens een van de eerste retailers die het belang van CRM en data inzag. Hij benadrukt het belang van dicht bij jezelf te blijven, authentiek te zijn en dat elk merk zijn eigen DNA moet bewaken en bewaren. - Bart Claes est CEO de l'entreprise de vêtements 'CRG' (Claes Retail Group), réputée pour ses marques JBC et Mayerline. Il a récemment repris au groupe FNG la marque de mode CKS et les marques pour enfants Fred & Ginger et Baker Bridge. Bart est un faiseur de marques dynamique et un des premiers retailers à avoir compris le rôle crucial du CRM et des données. Il souligne l'importance de rester en accord avec soi-même, d'être authentique et, pour chaque marque, de défendre et préserver son ADN.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.21.307009v1?rss=1 Authors: Wu, G., Wei, X., Wang, X., Liang, X., Wei, Y. Abstract: Mature embryos were used as explant for embryogenic callus (EC) induction, and then EC further developed to form somatic embryos during somatic embryogenesis (SE) of Ormosia henryi Prain, however, some mature embryos could induced non embryogenic callus (NEC), browning callus (BC) or snowflake callus (SC). The present study was carried out to analyse the biochemical events and histochemical changes at different SE stages in 0. henryi. The contents of their energy substances, H2O2, endogenous hormones and enzyme activities were measured. The results showed that the contents of soluble sugar, starch, the activities of PPO, SOD, APX, POD, the ratios of IAA/ABA, IAA/GAs, AUX/GAs, AUX/ABA decreased gradually at different SE stages; in contrary, the contents of soluble protein, H2O2, all kinds of endogenous hormones increased gradually; however, CAT activity and the ratios of IAA/CKs, AUX/CKs, ABA/CKs, GAs/CKs increased first and then decreased. The high contents of GAs, ABA, the high ratios of ABA/CKs, GAs/CKs and the low ratios of IAA/ABA, IAA/GAs, AUX/GAs, AUX/ABA were the reasons why callus could not form EC. The low enzyme activities, the low contents of energy substances and H2O2 were related to the NEC formation; the high contents of soluble sugar, H2O2, AUX, CKs and PPO activity and the low conent of soluble protein were the basic reasons for BC formation; the high energy substances contents and the low activities of SOD, POD were easy to form SC. Copy rights belong to original authors. Visit the link for more info
CKS is a french Techno DJ and Producer based in Paris, France. CKS always tries to create sets which will bring you into a spirited journey. His style goes from deep and minimal to mental and dark techno CKS created an exclusive mix and I am very happy to release right now. http://www.lowfrequencypodcast.net https://www.facebook.com/lowfrequencypodcast https://www.facebook.com/cksproducer/ https://soundcloud.com/cksmusic
Vibe Tribe!!!!!!!!!! I am SO pumped to be back after a much needed reevaluation of, well... my life. The podcast and my brand are entering a new phase as I purge some more old conditioning and move forward into my authentic mission:FAITH♡FITNESS♡FREEDOMIn this episode I touch base with you on where the heck i've been, what's going on with me and the podcast, and what these three things mean. We touch on people pleasing, purpose, mission, lessons, limitations, and so much more. This was a jam-packed episode with ALL of my brainf*Cks from the last few months (why yes, we do curse here now ;) I hope you love it as much as I LOVE YOU ! Energy ReportSupport the show (https://pod.fan/maximum-vibes-podcast)
Una entrevista a la distancia con la Maestra Claudia Gomez Gutierrez, donde nos platica sus primeros pasos en las Artes Marciales, también nos narra algunos detalles de como fue su camino a su cinta negra. En la entrevista nos cuenta como fue su encuentro con su actual maestro Javier de la Torre. Juntos han llevado a CKS a ser lo que es el dia de hoy, una escuela dinámica como ella la nombra, divertida y tradicional. Siganla en sus redes sociales; https://www.facebook.com/claudiagomezgutierrez https://www.facebook.com/claudiakaratestudio/ @gomezgutierrezclaudia
It seems weird for someone to be interviewing me but that's just what we are doing! Stacy Brown my childhood best friend interviews me with all of the questions I usually ask my guests. I hope you enjoy it. I'm absolutely terrified to put myself out here like this - CKS
I veckans avsnitt babblar bla viktor och jens om ordspråk, släktforskning och att fylla 30. De har även kollat på CKs nya special som de har lite tankar om såklart. Stötta gärna podden på https://www.patreon.com/FALKENGBERG ni som redan gör de är hjältar, hjältar på riktigt inte som de i sjukvården. lol de är också hjältar såklart, men inte lika mycket som ni.
Podcast 160 of atomar audio, featuring cutting edge techno artists. This week we present you CKS from Paris, France. Enjoy! CKS @cksmusic Visit atomar audio on Facebook: www.facebook.com/atomar.audio
Get Your Journal Here: https://squareup.com/store/hammerfactor/ Ladies and gentlemen, we are back! 70 freaking 1…how did this happen. Anyway, we have an...
Get Your Journal Here: https://squareup.com/store/hammerfactor/ Ladies and gentlemen, we are back! 70 freaking 1…how did this happen. Anyway, we have an...
Episode 52 “They're gonna be nice to you” Shout Out to CKS for stoppingRIP Bushwick Bill•Crane Collapse in North Texas•E3 video game convention•U of A returns 26.5 million dollar gift to donor•World Donut Day•Central Park five head investigatory given a lot of backlash after documentary•Pride month•Future Save ME•Scriptures Tee Grizzley•Chris Brown•C3 turns 11 •NBA Playoffs•Tony Parker to retire•Ja Rule on the Breakfast Club & More!
Apps for nurses + and other toolsDo you want apps for nurses, pharmacists, physician associates or other healthcare professionals to help in primary care? Then watch this and see tools to help you in practice, help patients, your learning and benefit you. Click the image below to watch the full video. Subscribe to or follow the eGPlearning platform for more videos, app reviews and content to support technology-enhanced primary care and learning.
What is the best haematology app?Watch this review of Buku Haematology - a useful clinical reference resource that details how to manage haematological investigation results, work up for common haematological conditions and emergencies.With a clean interface and clear explanations and reference to BMJ, CKS and national guidance it really is a valuable resource for anyone in primary care.The highs and lows section covers individual test results and the implications of them to help clinicians understand how to manage the results in the context of each patient.The coagulation section gives useful guides on problems with coagulation including FAQs on DOACs like Rivaroxaban.The workup section explains common presentations and considerations for haematological conditions and how to manage from a primary care perspective and what point to refer.The obstetric section has useful criteria for managing anaemia in pregnancy. The emergency section helps guide how to manage complex haematological emergencies.Created by Dr Alex Langridge and Prof Steven O'Brian it really is a useful app that is updated in content on a regular basis.Check out this app in detail use the link below to download it: https://bukuhaem.appyourself.net/?web...Subscribe to or follow the eGPlearning platform for more videos, app reviews and content to support technology-enhanced primary care and learning.Facebook - https://www.facebook.com/Egplearning/Twitter - https://twitter.com/egplearningWebsite - https://egplearning.co.uk/Support: https://patreon.com/egplearning
Stephen White shared his journey from Madison, WI, to various ventures combining music, communities, DJing, and tech, which led him to Gracenote and now Dubset and MixBANK. He shared his observations on early streaming and in shifting from one type of B2B model to another. He discussed international trends, the role of curation by DJs, and the hard challenges that Dubset had to overcome to get to this spot. Guest: Stephen White, CEO, Dubset Stephen is the CEO and Chairman for Dubset Media Holdings, and joined Dubset as CEO in February 2015. Prior to joining Dubset, he as CEO and President at Gracenote from 2012-2014. White held numerous roles for the company across 14 years and played a critical role in growing the company from a small start-up, focusing on music technologies and information, into a digital entertainment leader that now touches millions of music and movie fans around the globe. In his role as president, White oversaw all company strategy and operations, and was responsible for growing Gracenote’s core business. Before joining Gracenote, he was VP of development for streaming music start-up Echo.com, which was one of the first companies to combine group content streaming and community features. Prior to Echo.com, he was a senior director and executive producer for CKS, a media consultancy based in Silicon Valley where he lead teams in the creation of web properties such as the Apple online store and GM.com. He began his career as a reporter and writer. Site: MixBANK LinkedIn https://www.linkedin.com/in/stephenhwhite/ Twitter: @dubset and @swhite415
## AnthroAlert## Episode 26: STEMOriginally aired 15 December 2017 on bullsradio.orgDr. Rebecca Campbell is our guest this week.Dr. Campbell is part of a team of researchers at the University of Connecticut and the University of South Florida, with affiliates elsewhere, working on a project exploring how social capital and cultural models impact the retention and degree attainment of women and underrepresented minorities in STEM undergraduate programs. The research is supported by a grant from the National Science Foundation and is led by the PI, Dr. Gladis Kersaint, who is the Dean in the Neag School of Education at UConn. The research team includes an interdisciplinary team of researchers including anthropologists, sociologists, methodologists, educators, and engineers who are using their collective expertise to address the research questions being examined. Other members of the team include Dr. Chrystal Smith and myself who moved to UConn with Dr. Kersaint and the remainder of the USF team that includes Dr. George MacDonald and Mr. Reginald Lee at the Center for Research, Evaluation, Assessment, and Measurement and the College of Education here at USF; Dr. John Skvoretz, Distinguished University Professor of Sociology; Dr. Kingsley Reeves, Assistant Professor of Industrial & Management Systems Engineering and Dr. Hes Wao formerly of USF Health.This mixed-methods research is guided by the collective and interdisciplinary expertise of the research team and utilizes approaches from each of the disciplinary areas. For example, we use cognitive anthropology theory to think about cultural models, and anthropological research methods, such as Think Alouds and Freelisting, which help us increase reliability and validity of our survey and interview methods. Ego Network Analysis stems from Sociology, and we use it to understand social capital by looking at the people or influencers who helped our survey respondents get into and succeed in engineering. From education, we incorporate linear logistic test model (LLTM) to provide conceptual knowledge states (CKS) estimates; basically that means we designed survey items to measure concepts important in our research. These include Academic Preparation, Persistence & Success, Resources, Departmental Support, Relationships & Support, Limitations, and Fit.There were nearly 2,200 students in our first survey, and we have followed them from their freshmen year of engineering until now, which is their fourth year as students. We’ve conducted the first set of interviews with a subsample of 55 women and underrepresented engineering students. There are 10 colleges of engineering that cater to different types of student populations in our four-year longitudinal study. Our important outcome variables are: 1) the decision to pursue engineering undergraduate degrees and 2) retention to the fourth year of the degree program. We are in the process of analyzing data and deploying our fourth survey and second set of interviews. We’ve presented our interim findings at conferences, to the National Science Foundation, to our participating universities, and through journal articles under review.Findings include those listed in our 2016 Annual Report, which will be discussed during Friday’sradio show.Listen Live Friday at 3 PM EST https://tunein.com/radio/Bulls-Radio-897-s230635/## Podcast link## Video link## Album art photo credit:Oliver Thompsonhttps://flic.kr/p/9zVPYBCC License: https://creativecommons.org/licenses/by/2.0/## Intro music credit:Awel by stefsaxhttp://ccmixter.org/files/stefsax/7785http://creativecommons.org/licenses/by/2.5/Urbana-Metronica (wooh-yeah mix) by spinningmerkabahttp://ccmixter.org/files/jlbrock44/33345https://creativecommons.org/licenses/by/3.0/There's A Better WAY ! by Loveshadowhttp://ccmixter.org/files/Loveshadow/34402https://creativecommons.org/licenses/by/3.0/"Jungle Tracking" by pingnewshttp://ccmixter.org/files/pingnews/13481https://creativecommons.org/licenses/by/3.0/ See acast.com/privacy for privacy and opt-out information.
In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part IV, Peter and Tom review the history and current use of drugs to prevent cardiovascular disease. They also discuss why some drugs appear to be more effective than others, an in-depth conversation about niacin, cholesterol and brain health, and the futility of using CKs (creatinine kinase) and liver function tests to identify adverse effects in statins, to name a few topics in this episode. We discuss: Bile acid sequestrants and statins [2:00]; Ezetimibe (Zetia) [15:00]; PCSK9 inhibitors [27:30]; Fibrates [41:00]; Fish oil, DHA, and EPA [1:01:00]; Niacin [1:05:15]; PCSK9 inhibitors [1:23:45]; Cholesterol, statins, and the brain [1:30:00]; Elevated creatine kinase (CK) and liver function tests (LFTs) on statins [1:50:30]; and More. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.
SUFE or not SUFE? That is the question! Dr Colin Gilhooley joins us at DREEAM to talk us through 'The Child with a Limp' including: - Red flags - When to suspect non accidental injury (more of that later!) - The most common causes in each age group and some rarer ones too - When to take blood and when to image The guidance mentioned is based on the NICE 'Acute Childhood Limp' Clinical Knowledge Summary You can find the blog entry including links to the CKS and the #TakeVisually for this episode at https://www.takeaurally.com/paediatric-emergency-medicine/2018/8/17/the-child-with-a-limp Don't forget to subscribe via SoundCloud and iTunes Take Aurally and NUH DREEAM are both on Facebook and Twitter Next week's episode is the second in our Arrhythmia series on Bradyarrhythmias!
We talk plenty of Taiwan-US issues, Tiananmen Square, future plans for a famous statue of CKS, assisted suicide and the end of an era for TSMC.
We talk plenty of Taiwan-US issues, Tiananmen Square, future plans for a famous statue of CKS, assisted suicide and the end of an era for TSMC.
Roto Pope Founder and co-host, Aaron Sauceda, interviews Corey Kluber Society's Matt Esposito in a special Trout Wars Fantasy Baseball edition. Aaron and Matt discuss a variety of topics, including: - Early-season success of Matt's Braves (including CKS's own, Ozzie Albies - Key learnings from last season's April 1st place prize, but 2nd place finish - Early success of CKS players (Kurt Suzuki, Freddie Freeman, Travis Shaw, Corey Kluber, Dylan Bundy, etc.) - Looming threat/team Matt is thinking about - Zach/Boppas shoutout! - Much more!
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Top Of Show Sponsors: CKS Mainstreet Rants and Raves Sponsor: Calleva Subscription Options: Itunes: https://itunes.apple.com/us/podcast/amongstit-inc/id1095013227?mt=2 Stitcher: http://www.stitcher.com/podcast/john-grace/the-hammer-factor?refid=stpr RSS Direct Feed:...
Laura Porto Stockwell Laura Porto Stockwell has developed a strategy process that connects the dots between business goals, brand aspirations, market opportunities, and user needs. The intersection of those elements, she says, "Is where the magic happens." Laura applies her strategic approach to both top-level digital strategies and to content strategies for her clients as the CEO of Big Thinkers Society. We talked about: her transition from community journalism to digital agency work her pioneering content strategy work at early digital agencies like Ikonic, marchFIRST, and Razorfish her content-strategy process the relationship between content strategy and digital publishing the ongoing challenges of prying content out of clients the relationship between digital, branding, and content strategies her definitions of strategy and content strategy her interest in media ecology and digital literacy Laura's Bio Laura Porto Stockwell is the CEO and Founder of Big Thinkers Society, an agency that helps organizations embrace digital to connect with the world in new ways and helps professionals level up their strategic skills through flexible, online classes. Over the past 25 years, Laura has brought innovation and inspiration to clients including Ford, Microsoft, Nike, T-Mobile, Toyota, and the Bill and Melinda Gates Foundation. And as an executive leader at agencies across the U.S. and Italy, she's helped bring a culture of strategy to creative environments. Laura is a regular speaker at industry events as well as a frequent guest lecturer at the University of Washington. She holds a B.A. in Journalism from the University of Colorado at Boulder and an M.A. in Media Studies from The New School in New York City. Video Here's the video version of our conversation: https://youtu.be/jd0qj2Qf4kQ Show Notes/"Transcript" [Not an actual transcript - just my quick notes on first listen-through] 0:00 - my intro - journalism > digital strategy > content strategy 1:00 - Laura intro - content strategy near and dear to her heart - journalism degree - off to Prague - newspaper community reporting, translated nicely to digital, since there's so much community - first digital job report at Seattle Times - put whole newspaper online on bulletin board every day - next 10 years at agencies - Razorfish, marchFirst, etc. in LA, San Francisco, Milan, New York, and Seattle - started 4 years ago. 3:10 - content strategy in late 1990s 3:35 - story of marchFIRST - Ikonic proposal writing working with CD-ROM content strategy group - "fearless leader" there was Eric Johnson, a total content-strategy visionary - great group of folks - USWeb bought them, and then merged with CKS agency, then purchased/merged and became marchFIRST (still gets emails from colleagues there every March 1) - became a prominent global agency - she moved to LA and ran content strategy for southwest - 2000 or so web bust sank the company - 2004 Razorfish with Karen McGrane some of the pieces picked up there - 6:15 - what was content strategy then? 6:25 - when at Seattle Times, she founded ST WebWorks, launched web dev team to build sites for local advertisers - team was developer & designer, assumption was that client would provide content - OK for 1, 2, 3- page website, but realized need to understand content better - she can't find content-strategy explainer video: fake client at desk, cartoon-ey, put cocktail napkin notes online, culminates with UX, designer, and content person skipping through a park together - still an obstacle today, content never ready - had to figure out a strategy - developed a documented process (that she still has) for strategy (market and user needs), moving into structure (taxonomy, metadata, SEO, etc) > creation > maintenance - 2004 at Razorfish, as content strategist for a Fortune 10 company, did a content audit - found dated content, e.g. - so need processes in place to maintain content - that ...
Laura Porto Stockwell Laura Porto Stockwell has developed a strategy process that connects the dots between business goals, brand aspirations, market opportunities, and user needs. The intersection of those elements, she says, "Is where the magic happens." Laura applies her strategic approach to both top-level digital strategies and to content strategies for her clients as the CEO of Big Thinkers Society. We talked about: her transition from community journalism to digital agency work her pioneering content strategy work at early digital agencies like Ikonic, marchFIRST, and Razorfish her content-strategy process the relationship between content strategy and digital publishing the ongoing challenges of prying content out of clients the relationship between digital, branding, and content strategies her definitions of strategy and content strategy her interest in media ecology and digital literacy Laura's Bio Laura Porto Stockwell is the CEO and Founder of Big Thinkers Society, an agency that helps organizations embrace digital to connect with the world in new ways and helps professionals level up their strategic skills through flexible, online classes. Over the past 25 years, Laura has brought innovation and inspiration to clients including Ford, Microsoft, Nike, T-Mobile, Toyota, and the Bill and Melinda Gates Foundation. And as an executive leader at agencies across the U.S. and Italy, she’s helped bring a culture of strategy to creative environments. Laura is a regular speaker at industry events as well as a frequent guest lecturer at the University of Washington. She holds a B.A. in Journalism from the University of Colorado at Boulder and an M.A. in Media Studies from The New School in New York City. Video Here's the video version of our conversation: https://youtu.be/jd0qj2Qf4kQ Show Notes/"Transcript" [Not an actual transcript - just my quick notes on first listen-through] 0:00 - my intro - journalism > digital strategy > content strategy 1:00 - Laura intro - content strategy near and dear to her heart - journalism degree - off to Prague - newspaper community reporting, translated nicely to digital, since there's so much community - first digital job report at Seattle Times - put whole newspaper online on bulletin board every day - next 10 years at agencies - Razorfish, marchFirst, etc. in LA, San Francisco, Milan, New York, and Seattle - started 4 years ago. 3:10 - content strategy in late 1990s 3:35 - story of marchFIRST - Ikonic proposal writing working with CD-ROM content strategy group - "fearless leader" there was Eric Johnson, a total content-strategy visionary - great group of folks - USWeb bought them, and then merged with CKS agency, then purchased/merged and became marchFIRST (still gets emails from colleagues there every March 1) - became a prominent global agency - she moved to LA and ran content strategy for southwest - 2000 or so web bust sank the company - 2004 Razorfish with Karen McGrane some of the pieces picked up there - 6:15 - what was content strategy then? 6:25 - when at Seattle Times, she founded ST WebWorks, launched web dev team to build sites for local advertisers - team was developer & designer, assumption was that client would provide content - OK for 1, 2, 3- page website, but realized need to understand content better - she can't find content-strategy explainer video: fake client at desk, cartoon-ey, put cocktail napkin notes online, culminates with UX, designer, and content person skipping through a park together - still an obstacle today, content never ready - had to figure out a strategy - developed a documented process (that she still has) for strategy (market and user needs), moving into structure (taxonomy, metadata, SEO, etc) > creation > maintenance - 2004 at Razorfish, as content strategist for a Fortune 10 company, did a content audit - found dated content, e.g. - so need processes in place to maintain content - that ...
In this episode Joseph Warren interviews Nick Tanis, Catholic father and Principal of Christ The King Catholic School in Tampa, FL about his struggles with holiness. Learn more: www.CKS-school.org Get More: www.BrokenCatholic.com Become A Patron of The Show!! Get Patron-Only Rewards
We had the opportunity to interview branding and marketing expert: Bernie Schroeder. Bernie is notorious for helping Amazon get their start, working with Apple & Pixar, and was a partner in one of the largest integrated branding agencies in the world. He is currently a mentor in the SDSU entrepreneurship program and the author of a new book for Millennial Marketers titled “Brands & Bullshit”
Dr. Carolyn Lam: Welcome to "Circulation On The Run", your weekly podcast summary and backstage pass to the journal and its editors. I'm Dr. Carolyn Lam, associate editor from the National Heart Center and Duke National University of Singapore. Today's feature paper looks at the early use of N-Acetyl Cysteine with nitrate therapy in patients undergoing primary PCI for STEMI. More soon right after this week's summary of original articles. The first paper identifies a novel association between Phosphatidyl Choline Transfer Protein, or PCTP expression, in the blood, and death or myocardial infarction in patients with cardiovascular disease. Now, PCTP regulates intermembrane transfer for phosphatidyl choline. Platelet PCTP expression has been shown to be associated with increased platelet responses upon activation of protease-activated receptor four thrombin receptors. In today's paper, first authors Dr. Mao and Songdej, corresponding author Doctor Rao, and colleagues from the Temple University School of Medicine in Philadelphia used DNA protein binding studies and human erythroleukemia cells, as well as luciferase reporter studies to show that PCTP is a direct transcriptional target of RUNX1, a major hematopoietic transcription factor that regulates platelet production and function. Furthermore, in 587 patients with cardiovascular disease, the authors showed that PCTP expression in the blood correlated with RUNX1 expression and was independently associated with future death or myocardial infarction. Thus, regulation of PCTP by transcription factor RUNX1 may play a role in the pathogenesis of platelet-mediated cardiovascular events. The next paper provides molecular insights into cardiac fibrosis and shows that bone marrow cells are involved in cardiac fibrosis during pathological stress. Drs. Kishore, Verma and colleagues from Lewis Katz School of Medicine and Temple University of Philadelphia hypothesize that interleukin-10 inhibits pressure overload-induced homing of bone marrow fibroblast progenitor cells to the heart, and inhibits their trans-differentiation to myofibroblasts, thus attenuating cardiac fibrosis. To test this hypothesis, the authors used pressure-overload in wild-type and interleukin-10 knockout mice by transverse aortic constriction, and used chimeric mice to determine bone marrow origin. They further isolated fibroblast progenitor cells from mouse bone marrow for mechanistic studies. They found that, in addition to resident cardiac fibroblasts, bone marrow-derived fibroblasts significantly contributed to progression of pathological cardiac fibrosis, and that pliotropic antiinflammatory interleukin-10 inhibited the recruitment and trans-differentiation of bone marrow fibroblast progenitor cells in the pressure-overloaded myocardium. At a molecular level, they showed that interleukin-10 inhibited TGFβ SMAD2-3 signaling in activated bone marrow fibroblast progenitor cells. Furthermore, inhibition of TGFβ SMAD2-3 signaling mediated micro-RNA21 maturation was a novel mechanism by which interleukin-10 inhibited bone marrow progenitor cells-mediated cardiac fibrosis. Thus, selective inhibition of bone marrow cells homing to the heart and of fibrotic signaling using interleukin-10 or selective RNAs might inhibit the transition of physiological hypertrophy to heart failure, and may be a potential therapeutic target to treat or prevent the development of hypertrophic remodeling. The next study looks at the risk of major bleeding in patients receiving ticagrelor compared to Aspirin after a TIA or Acute Ischemic Stroke in the SOCRATES study. As a reminder, the SOCRATES trial was the first outcome study with ticagrelor in patients with Acute Ischemic Stroke or TIA, who were given ninety days of monotherapy with ticagrelor, 90 milligrams, twice daily and compared with those given aspirin 100 milligrams daily. The trial found that ticagrelor was not superior to aspirin in reducing the primary composite endpoint of stroke myocardial infarction or death. In today's study, Dr. Easton and colleagues from University of California San Francisco aimed to describe the bleeding profile of monotherapy with ticagrelor versus aspirin in this population of patients with Acute Ischemic Stroke and TIA, to characterize major bleeding based on the PLATO, TIMI and GUSTO bleeding definitions, and to identify factors associated with major bleeding. They found that PLATO major bleeds occurred in 0.5% of patients on ticagrelor and 0.6% of patients on aspirin. The most common locations of major bleeds were intracranial and gastrointestinal. Intracranial hemorrhage was reported in 12 patients, or 0.2%, on ticagrelor and 18 patients, or 0.3%, in aspirin. Independent of bleeding classification, PLATO, TIMI or GUSTO, the relative difference between treatments for major or severe bleedings was similar. However, non-major bleeds were more common on ticagrelor. Thus, this paper contributes important data on the bleeding profile of ticagrelor in patients with acute cerebral ischemia, provides some reassurance that there's no increased risk of major bleedings with ticagrelor compared to aspirin, including intracranial bleeds, however, a numerical increase in minor bleedings with ticagrelor. The next paper tells us that single 24-hour urine collections may be useful for estimation of average sodium intake in populations. However, for a reliable estimation of cardiovascular and renal risk, multiple 24-hour urine collections may be needed. First author, Dr. Olde Engberink, corresponding author, Dr. Vogt and colleagues from Academic Medical Center Amsterdam selected 574 adults with EGFR above 60, an outpatient 24-hour urine sample, and at least one collection during a seventeen year follow-up. Sodium intake was estimated using a single baseline collection, and the average of samples that were collected during a one, five, and fifteen year follow-up. They found that estimates of daily sodium intake changed more than 0.8 grams in half of the subjects when using multiple follow-up collections instead of a single baseline collection. The way of estimating sodium intake significantly affected the observed relationship between sodium intake and long-term outcome. Hazard ratios for cardiovascular and renal outcomes changed up to 85% when multiple follow-up 24-hour urine collections were used, instead of a single baseline collection. Thus, in summary, relative to a single baseline, the use of subsequent 24-hour urine samples resulted in different estimations of an individual's sodium intake, while population averages remained similar. This had significant consequences for the association between sodium intake and long-term cardiovascular and renal outcome. That wraps it up for your summaries this week. Now to our featured discussion. Today for our featured discussion, we are talking about approaches to cardio protection. Now, we all know that the mortality rates in STEMI has improved over the last few years, because we've gotten better at reperfusion therapy with primary PCI, as well as effective secondary prevention therapy. However, the incidents and severity of heart failure following STEMI has been rising and thus, cario-protective therapies are of great interest to prevent heart failure and improve overall clinical outcomes following STEMI, following primary PCI. Over the years, a number of cardio-protective therapies have been tried, but have either been unable to reduce MI size or improve clinical outcomes following STEMI, but in this week's journal, we have an exciting trial, very interestingly of two old cardio-protective therapies showing a lot of promise in this area. And to do discuss this, I am so pleased to have the corresponding author, Dr. John Beltrame from University of Adelaide in Australia, as well as associate editor from Brigham and Women's Hospital in Boston, Massachusetts, Dr. Laura Mauri. John, you know, in my introduction I said this is very interesting. You're actually combining two old therapies, N-acetylcysteine and nitroglycerin in your approach in this trial. Now, both these drugs have been around for a long time. Please share with us what led you to think that a combination would work, what made you test the combination, and what makes your trial different from the other reperfusion studies before. Dr. John Beltrame: So, nitroglycerin, of course, has been utilized to treat myocardial infarctions for many years, has been shown to reduce the chest pain in that scenario, but little reward in perhaps reducing infarct size. And one of the main benefits of that people don't know is the vasodilation effect that it has on the coronary arteries, as well as reducing the wall stress. So, what we thought to combine it with N-acetylcysteine, which potentiates nitroglycerin effects, but also is a free radical scavenger. So therefore it would actually also work on reperfusion injuries. So these have a very synergistic effect, and therefore we expected to have good benefits. The ... because we're also looking at an anti-ischemic therapy with a reperfusion protective therapy, we wanted to introduce it as soon as possible. And so this drug was initiated in the emergency department as patients arrived, and then taken off to the cath lab where it was continued. We also began to ensure that we had adequate N-acetylcysteine, which I'll probably refer to as NHC from now on, as much on board as possible before we actually opened the artery. We gave high dose N-acetylcysteine at 20 milligrams in the first thirty minutes, and then at a slower rate for the next twenty-four hours. So for the first hour we gave it at 20 milligrams a minute, and then thereafter 10 milligrams a minute. And then, the actual study. We had patients randomized and double-blind placebo control trial, multiple sites here within South Australia with the primary endpoint being myocardial infarct size on early cardiac MRIs. So they got to see the opportunity to have a smaller sample size than many of the conventional infarct studies, and the key finding was in that early MRI, we saw an absolute 5% reduction in infarct size, which was an exciting find for us and this we expect to translate to a significant reduction in cardiovascular events and that's where I guess we're going in the future, is that we need to now undertake a study where we show that the combination of these two drugs also impacts on cardiac events. Dr. Carolyn Lam: How beautifully summarized, John. And really, congratulations on such an impactful and elegantly done study. I like the way you highlight it, though. Basically, you gave this drug earlier than most other trials of reperfusion therapies, because you gave it even before the primary PCI procedure as most cardio-protective strategies were tried within the cath lab. Would that be accurate? Dr. John Beltrame: Exactly right. So, whereas a number of the studies would take the patient with the STEMI to the cath lab, undertake the diagnostic angiogram and the diagnostic angiogram would then confirm that this was occluded, then they would introduce the cardio-protective agent and then proceed on to open up the artery. Whereas we had an opportunity for sort of ... at least twenty to thirty minutes before the artery was opened to actually have those drugs on board. And so, in a number of cases, we improved the patency of the vessel when we got to the diagnostic angiogram. So it's a two-point strategy, one anti-ischemic and one cardio-protective in terms of reperfusion injury. And we think that future trials in this area need to address both those conditions. Dr. Carolyn Lam: I can think of no better person to comment on being able to do these trials and the future of these trials than Laura. Laura, what are your thoughts? Dr. Laura Mauri: Thanks Carolyn. John, that was a great summary and I think you're really to be commended, because this is just such a challenging area to be doing trials in, but that's really what we need. And you know, most of the trials have focused on early procedure success for therapies that we currently use, rather than showing documented benefit in longer-term endpoints. But as you mentioned earlier, Carolyn, we really do still have patients who would benefit from therapies that may reduce infarct size. I think it's really remarkable, John, that your study was able to intervene early in the emergency room, as we know as clinicians that's not easy to do, not only to activate the quick pathways of care that we need for STEMI, but then on top of that to lay on a randomized trial, but I think it's incredibly important. What are you foreseeing as the challenges? As you think about your next steps in rolling this out to a ... potentially a larger trial and implementing such a study? Dr. John Beltrame: As with many trials, it's ways of recruitment, because a study like this is not gonna be funded by industry, you need to be looking at ... here within Australia, be looking at government authorities to put in an application for funding and then, it's a matter of recruiting. That's one of challenges we came across in doing this particular study, and this relates particularly, I guess, to the MRI endpoint, is the number of patients that were claustrophobic and therefore we couldn't actually perform the cardiac MRI, and so your primary endpoint ... you missed out. And so again, there's going to be frustrations like that and a much larger trial, which will need to involve even more centers. But funding that's ... for much of the research, I guess, it will be the challenge, because we've got two agents as Carolyn mentioned in the beginning that have been around for a long time and are certainly unlikely to attract any industry funding. Dr. Carolyn Lam: John, I have a question about the design as well. Of the current and maybe a future trial, because I'm left with the question, was it your early intervention? Was it the outcome you chose? Or was it one drug or the combination? And so, you did not do a factorial design in this trial. Are there plans to look at that, or do you the combination ... it's so obvious that two separate drugs don't need to be tested? Dr. John Beltrame: Very good question. So, you're quite correct, we can't be absolutely confident in terms of the mechanism, because we had one opportunity, I guess, to do the study and so we wanted to keep a simplified design, and that's what we gave everyone; a background of nitroglycerin and then just randomized the N-acetylcysteine. But we think it's actually the combination of the two that makes the benefits, because as you would be aware, the synergistic benefits is that the N-acetylcysteine potentiates the effect of the nitrates, potentiates the vasodilating properties, potentiates it's anti-platelet properties also. And so we think it's a combination of the two. Dr. Laura Mauri: John, it's interesting ... the use of the cardiac MRI endpoint, as we've all seen, it's being used more and more frequently, but at the same time, it's new for us, right? So you've raised some of the challenges and the practical execution of getting patients who can tolerate it, especially after an acute hospitalization. But the classical endpoint has been SPECT imaging as a surrogate endpoint for mortality in myocardial infarction. Of course, that's based on very large trials showing correlation, but the MRI should really give much better resolution, so I think that's really a very logical next step. But I think the more data that we get across multiple different trials, the better we can validate that endpoint and see how it might differ from the classical surrogate endpoints that we've had for myocardial infarction. Other than the efficiency of looking at MRIs, do you have other observations when you look at MRIs at endpoint compared with some of the traditional endpoints like SPECT? Dr. John Beltrame: Not SPECT so much, but to follow on exactly what she was saying, we all also measured serum creatine kinase, so CK, values. And because of the larger spread of the data and therefore the need to have a larger sample size, although we certainly saw a trend of improvement in CKs as a marker of infarct size, we didn't achieve statistical significance, but with the MRI because we had more precise measurements, that gave us a smaller margin of error and therefore, we were able to see a difference between the two treatments. So certainly I think in the future, the MRI is certainly a very good way to evaluate agents in this particular area. Dr. Laura Mauri: It's nice to see the consistency that you saw across the different endpoints. Dr. Carolyn Lam: That's true, but I do have a question though, as an Echo cardiologist here, your three-month assessment of the ventricular remodeling, if I read it right, there was no change detected at three months. Would you like to comment on that? Dr. John Beltrame: What we saw in terms of the infarct size, we still saw a difference. I think what you might be referring to, the infarct size was a little bit smaller, so that's just ... over time the we feel like the scar contracts down. But I'm not sure if you're also referring to the ... Dr. Carolyn Lam: LV dimensions and injection fraction. Dr. John Beltrame: The injection fraction's interesting, because when we looked at that ... because we found no difference in the injection fraction. Now, if you take a look at the actual values, they're almost normal and I think that says something to where we are in terms of the management of acute STEMIs, because we preserved the left ventricular function, because there were normal ejection fractions, so we couldn't make them better than what we had in placebo, so that is something to primary PCI, I think. Dr. Carolyn Lam: That's a great answer. Thank you, John. And Laura? Dr. Laura Mauri: John, your group is really to be commended for conducting such a high-quality trial in this very challenging area. We've been victims of our own success, I think, in this space because the mortality rates have obviously declined after MI, infarct size is on the decline with early reperfusion. Getting in there with attempted therapies is a race when you're also trying to achieve fast door-to-ballon times, but it's still an important area and one we can only address with careful, randomized trials with important therapies. So I want to congratulate you and your group, it's really a step in the right direction. Dr. Carolyn Lam: You've been listening to "Circulation On The Run", thank you so much for joining us, and don't forget to tune in next week!
Episode One of The VVRP! In this episode Chandler discusses Australia & New Zealand, the new 20700 battery and reviews the CKS icon 200W box mod from Cloud Kicker Society! He also invents a Bod Mox. If you want to make your own Clapton wire, Lezlee shows you how! Enjoy!
Let's face it...not going to be a good season. Vandy broke our collective hearts. It sucked. Shows aren't fun anymore because I hate the doom and gloom stuff...but thats where we are. WE ARE the dumpster fire now...hope CKS can turn it around.
Le podcast radio exclusif du Cut Killer Show [N°1 FM],le samedi de 22h à minuit en direct sur Skyrock. Chaque semaine,retrouve les dernières bombes Rap et Rnb du moment remixés par Dj Cut Killer.
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CUT KILLER SHOW 839 / 23-11-13 : SESSION HH # 2
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New expo at CKS showcases one of the best-preserved mammoths!
New expo at CKS showcases one of the best-preserved mammoths!
In the present study, we examined the distribution of 6 groups ofintermediate filaments (IFs; cytokeratins, CKs, vimentin, synemin,desmin, glial fibrillary acidic protein and lamins) in oocytes andfollicular walls of the Japanese quail (Coturnix japonica) during theirdevelopment using immunohistochemical and ultrastructural techniques. Adistinctly vimentin- and synemin-positive Balbiani body, which is atransient accumulation of organelles (mitochondria, Golgi complex andendoplasnnic reticulum) that occurs in the oocytes of all vertebratesincluding birds, could be detected in the oocytes of primordial andearly pre-vitellogenic follicles. In larger pre-vitellogenic follicles,the Balbiani body has dispersed and the positivity of the granulosacells appeared to concentrate in the basal portion of their cytoplasm.Our ultrastructural data demonstrated that the matrix of the Balbianibody consists of fine IFs, which may play a role in the formation anddispersion of the Balbiani body. Of the CKs studied (panCK, CK5, CK7,CK8, CK14, CK15, CK18 and CK19), only CK5 showed a slight positivestaining in both the theca externa and the Balbiani bodies ofpre-vitellogenic oocytes. In conclusion, our data, which describe thechanges in avian IF protein expression during folliculogenesis, suggestthat the functions of the IFs (vimentin and synemin) of oocytes andfollicular walls are not primarily mechanical but may be involved in thetransient tethering of mitochondria in the area of the Balbiani body andin the gain of endocrine competence during the differentiation ofgranulosa cells.
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