Podcasts about caltech

This is a two-part episode. The first ~30m covers the most important 2025 breakthroughs in polygenic embryo screening, while the second 30m focuses specifically on AI capabilities at the frontier of human knowledge. Both segments make predictions for 2026 and beyond.Links:Chinese billionaires, Philo-semitism, and the Chosen embryos:https://x.com/hsu_steve/status/2000206116823675078My talk from Reproductive Frontiers 2025 in Berkeley:https://www.youtube.com/watch?v=n64rrRPtCa8Previous episodes on frontier AI capabilities in math and theoretical physicshttps://www.manifold1.com/episodes/theoretical-physics-with-generative-ai-101https://www.manifold1.com/episodes/ais-win-math-olympiad-gold-prof-lin-yang-ucla-97Chapter Markers:(00:00) - Introduction (02:22) - Advancements in Polygenic Prediction of Human Traits (03:20) - Polygenic Risk Scores in Healthcare (08:15) - Embryo Selection and IVF (20:37) - Public Perceptions: billionaires and FOMO (31:40) - AI advances in 2025: High end capabilities and use of AI at the frontier of human knowledge (55:33) - Conclusion and predictions for 2026 –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

"Natural selectin is innovation ... that is when new things are invented in biology. The difference with humans is we have culture which makes us able to make innovations much faster."Are you interested in new forms of government? What do you think about betting markets – can they help our governance? How can we ensure the continuation of our cherished values? Interview with Robin Hanson, American economist and author. We will talk about his vision for the future of cities, cultural evolution, adaptability, innovation, and many more. Robin Hanson (born August 28, 1959) is an American economist and author known for his pioneering work on prediction markets and unconventional futuristic concepts. He currently serves as an associate professor of economics at George Mason University and was a research associate at the Future of Humanity Institute at Oxford University. He holds a PhD in social science from Caltech, as well as degrees in physics and the conceptual foundations of science. Robin is widely recognized for inventing the Logarithmic Market Scoring Rule used in prediction markets and for proposing "futarchy," a governance system determined by betting markets. He also originated the "Great Filter" hypothesis to explain the lack of observable extraterrestrial civilizations. His major publications include The Age of Em (2016), which models a future economy of brain emulations, and The Elephant in the Brain (2018), which explores hidden human motives. Additionally, Robin is a vocal advocate for cryonics.Find out more about Robin through these links:Robin Hanson on LinkedInRobin Hanson website@robinhanson as Robin Hanson on X@RobinHanson as Robin Hanson on YoutubeOvercoming Bias - Robin Hanson's blogThe Age of EM - book by Robin HansonThe Elephant in the Brain - book by Robin Hanson and Kevin SimlerRobin Hanson on WikipediaRobin Hanson on Google ScholarRobin Hanson at TEDConnected episodes you might be interested in:No.274 - Interview with Richard Gill about disruptive technologiesNo.294 - Interview with Erick A. Brimen about Prospera HondurasNo.380 - Interview with Adam Miller about DAOs as new governance typeNo.388 - Interview with Maurice Berger and Raquel Medrano Clemente about cultural evolutionNo.389R - Shall we vote on values, but bet on beliefs? What was the most interesting part for you? What questions did arise for you? Let me know on Twitter ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@WTF4Cities⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or on the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠wtf4cities.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ website where the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠shownotes⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ are also available.I hope this was an interesting episode for you and thanks for tuning in.Episode generated with ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Descript⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ assistance (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠affiliate link⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠).Music by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Lesfm ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Pixabay

Balancing the gut microbiome can transform the body's entire internal terrain—regulating immune function, reducing inflammation, influencing metabolism, and impacting brain health through the gut-brain axis. These interconnected systems play a critical role in the prevention and potential reversal of chronic illness. In this episode, Tee sits down with Martha Carlin, a pioneering citizen scientist and systems researcher who has spent the past decade uncovering the hidden links between the microbiome, chronic disease, and environmental toxins. After her husband was diagnosed with Parkinson's disease, Martha left a successful corporate career to investigate the deeper drivers of neurodegeneration and metabolic dysfunction, starting in the gut. Martha is the founder and CEO of The BioCollective, an innovative microbiome research company that has collaborated with leading institutions, including Caltech, the University of Chicago, and University College Cork. Her team developed the BioFlux™ metabolic modeling system and Sugar Shift®, a patented probiotic that has been clinically shown to reduce endotoxin (LPS), improve insulin resistance, and increase microbiome diversity. Throughout the conversation, Martha and Tee emphasize the importance of mindful choices around diet, water consumption, and reducing exposure to harmful chemicals to support a resilient microbiome. The episode delivers practical, science-backed insights for anyone seeking better overall health, with particular relevance for women focused on hormone balance, metabolic health, and long-term wellness. Connect with Martha and The BioCollective:  Martha's Website BiotiQuest Website Substack Instagram Facebook YouTube LinkedIn X Follow Therese "Tee" Forton-Barnes and The Green Living Gurus: Austin Air Purifiers: For podcast listeners, take 15% off any Austin Air product; please email Tee@thegreenlivinggurus.com and mention that you want to buy a product and would like the discount. See all products here: Austin Air The Green Living Gurus' Website  Instagram YouTube Facebook Healthy Living Group on Facebook Tip the podcaster! Support Tee and the endless information that she provides: Patreon Venmo: @Therese-Forton-Barnes last four digits of her cell are 8868 For further info, contact Tee: Email: Tee@thegreenlivinggurus.com Cell: 716-868-8868 DISCLAIMER: ALL INFORMATION PROVIDED HERE IS GENERAL GUIDANCE AND NOT MEANT TO BE USED FOR INDIVIDUAL TREATMENT. PLEASE CONTACT YOUR PROVIDER OR DOCTOR FOR MEDICAL ADVICE. Produced By: Social Chameleon

In this episode of SpaceTime, we uncover groundbreaking astronomical events and the latest advancements in space exploration.First Ever Super Kilonova DetectedAstronomers have made a significant discovery with the potential detection of the first ever super kilonova explosion. This extraordinary event, cataloged as AT 2025ULZ, is believed to have been triggered by a double supernova explosion, producing both gravitational waves and electromagnetic radiation. Lead author Manzi Kasliwal from Caltech's Palomar Observatory discusses how this unique phenomenon could reshape our understanding of stellar evolution and the formation of heavy elements in the universe. With only one confirmed kilonova event to date, this new discovery presents an exciting opportunity to explore the complexities of cosmic explosions.Blue Ghost 2 Spacecraft Shake TestFirefly Aerospace's Blue Ghost Mission 2 spacecraft has undergone rigorous shake testing at NASA's Environmental Test Laboratory. This critical assessment simulates the intense vibrations and acoustics experienced during launch, ensuring the spacecraft can withstand the harsh conditions of a rocket ascent. JPL engineer Michael Williams explains the importance of these tests in preparing spacecraft for successful missions, as the Blue Ghost 2 aims to deliver multiple payloads to the lunar far side next year.Shenzhou 20 Capsule Returns SafelyChina's Shenzhou 20 spacecraft has successfully completed an unmanned return to Earth after sustaining damage from space debris. Initially intended to bring a crew of Tigernauts back home, mission managers opted for a safe return without the crew due to concerns over a crack in the capsule's viewport. This decision highlights the importance of safety in space missions, while also providing valuable data for future flights.www.spacetimewithstuartgary.com✍️ Episode ReferencesAstrophysical Journal LettersNASA ReportsNature CommunicationsBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.(00:00:00) This is Space Time Series 28, Episode 152 for broadcast on 26 December 2025(00:00:47) Astronomers detect what could be the first ever super kilonova explosion(00:15:30) Firefly Aerospace's Blue Ghost 2 spacecraft undergoes shake testing at NASA's JPL(00:20:10) China's Shenzhou 20 capsule returns safely to Earth after damage from space debris(00:25:00) New study reveals the benefits of swearing during physical exertion

Tras el Big Bang, solo había hidrógeno, helio y un poco de litio. El oxígeno, necesario para hacer agua (H2O), tuvo que "cocinarse" en el interior de las primeras estrellas y ser expulsado al espacio después, cuando éstas murieron. Esto convierte a este descubrimiento en la reserva más grande y, sobre todo, la más antigua de agua que se conoce hasta la fecha. El agua, por lo tanto, no es una rareza moderna; es una parte intrínseca de la historia antigua del cosmos. El agua que han detectado no es líquida, como la de nuestros mares, sino una niebla "espesa" y "caliente" (en términos cósmicos) que envuelve por completo al agujero negro. En el cuásar APM 08279+5255, el agua no puede congelarse. La energía del agujero negro la mantiene en estado gaseoso, excitada, emitiendo señales de radio que han viajado por el universo durante 12.000 millones de años hasta llegar al espectrómetro Z-Spec en el Observatorio Submilimétrico de Caltech, en Hawái, y al interferómetro de Plateau de Bure en los Alpes franceses. Es gracias a estos instrumentos que hemos podido "leer" la firma química del agua a través del abismo del tiempo.

All but the last 20 minutes of this episode should be comprehensible to non-physicists.Steve explains where frontier AI models are in understanding frontier theoretical physics. The best analogy is to a “brilliant but unreliable genius colleague”!He describes a specific example: the use of AI in recent research in quantum field theory (Tomonaga-Schwinger integrability conditions applied to state-dependent modifications of quantum mechanics), work now accepted for publication in Physics Letters B after peer review. Remarkably, the main idea in the paper originated de novo from GPT-5.Links:X discussion - https://x.com/hsu_steve/status/1996034522308026435Companion paper: Theoretical Physics With Generative AI -  https://drive.google.com/file/d/16sxJuwsHoi-fvTFbri9Bu8B9bqA6lr1H/viewPhysics paper - https://arxiv.org/abs/2511.15935 | https://www.sciencedirect.com/science/article/pii/S0370269325008111Related discussion of AI and theoretical physics with Prof. Nirmalya Kajuri (IIT) and Prof. Jonathan Oppenheim (UCL) - https://youtu.be/BRuDd3l0e3kRelated video: AIs Win Math Olympiad Gold: Prof. Lin Yang (UCLA) – Manifold #97 - https://youtu.be/8JeRCqNg7RcChapter markers:(00:00) - Intro: AI discussion with specialized physics at the end (03:40) - The current AI landscape for science: frontier models, Co-Scientist, and recent math breakthroughs (11:01) - Why models help and why they fail: errors, deep confabulation, and the research risk (15:54) - The Generator–Verifier workflow: how chaining model inference suppresses mistakes (23:30) - Project origin: testing models on Hsu's older nonlinear QM/QFT work (30:35) - The “GPT-5 moment”: Tomonaga–Schwinger angle appears and produces the key equation (40:35) - Wild goose chases & a practical heuristic: axiomatic QFT detour; Generator-Verifier convergence (51:44) - Referee-driven test case: Kaplan–Rajendran model, past-lightcone geometry, and verification (55:55) - Tooling & outlook: automation prototype, chaining into “supermodels,” where this is headed (59:39) - Physics slides (advanced): TS integrability, microcausality, and why nonlinearity threatens locality –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

While humans were leaving the Stone Age and entering the Bronze, some Bristlecone pine trees grew from seeds to sprouts. They've been growing ever since. These 5,000-year-old pines are among the oldest organisms on Earth. Superlatives are also appropriate for the towering redwoods. Trees are amazing in many ways. They provide us with timber and cool us with shade, they sequester carbon and release oxygen, and are home to countless species. But they are also marvels of evolutionary adaptation. We consider the beauty and diversity of trees, and learn why their future is intertwined with ours. Guests: Kevin Dixon - Naturalist at The East Bay Regional Park District, Oakland, California Daniel Lewis - Environmental historian and senior curator for the History of Science and Technology at the Huntington Library, art museum and botanical gardens in Pasadena, California, professor of the natural sciences and the environment at Caltech, and author of “Twelve Trees: The Deep Roots of our Future” Featuring music by Dewey Dellay and Jun Miyake Originally aired January 25, 2025 Big Picture Science is part of the Airwave Media podcast network. Please contact advertising@airwavemedia.com to inquire about advertising on Big Picture Science. You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support! Learn more about your ad choices. Visit megaphone.fm/adchoices

While humans were leaving the Stone Age and entering the Bronze, some Bristlecone pine trees grew from seeds to sprouts. They've been growing ever since. These 5,000-year-old pines are among the oldest organisms on Earth. Superlatives are also appropriate for the towering redwoods. Trees are amazing in many ways. They provide us with timber and cool us with shade, they sequester carbon and release oxygen, and are home to countless species. But they are also marvels of evolutionary adaptation. We consider the beauty and diversity of trees, and learn why their future is intertwined with ours. Guests: Kevin Dixon - Naturalist at The East Bay Regional Park District, Oakland, California Daniel Lewis - Environmental historian and senior curator for the History of Science and Technology at the Huntington Library, art museum and botanical gardens in Pasadena, California, professor of the natural sciences and the environment at Caltech, and author of “Twelve Trees: The Deep Roots of our Future” Featuring music by Dewey Dellay and Jun Miyake Originally aired January 25, 2025 Big Picture Science is part of the Airwave Media podcast network. Please contact advertising@airwavemedia.com to inquire about advertising on Big Picture Science. You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support! Learn more about your ad choices. Visit megaphone.fm/adchoices

The story goes that Wolfgang Pauli, who first proposed the existence of neutrinos, was embarrassed to have done so, as it was considered uncouth to hypothesize new particles that could not be detected. Modern physicists have no such scruples, of course, but more importantly neutrinos turn out to be very detectable, given sufficient resources and experimental technique. I talk with neutrino physicist Ryan Patterson about what current and upcoming experiments teach us about neutrinos themselves, as well as implications for dark matter and why there are more particles than antiparticles in the universe.Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/12/08/228-ryan-patterson-on-the-physics-of-neutrinos/Support Mindscape on Patreon.Ryan Patterson received his Ph.D. in physics from Princeton University. He is currently Professor of Physics at Caltech. His research involves a number of aspects of experimental neutrino physics, including involvement in the NOvA and DUNE experiments.Caltech web pagePublications at inSpireSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jason Pruitt is the Women's Basketball Associate Head Coach at Indiana State University joining Head Coach Marc Mitchell's staff in June of 2024.Pruitt previously served as the Women's Basketball Head Coach at Elmhurst, where he helped the Bluejays to a nine-win improvement from the previous season while securing a spot in the CCIW Tournament for the first time since the 2018-19 season.Pruitt's experience also includes head coaching stops at La Verne, the University of Antelope Valley, and Bethesda University. He also spent time as the associate men's basketball coach at Caltech and the associate head basketball coach at the NSU University School.Prior to his time coaching, Pruitt spent a decade in the media industry in various positions at NBC, CBS, and ABC affiliates. As a player, Pruitt began his college basketball career at Calhoun Community College, where he won the NJCAA Alabama State Championship and played in the NJCAA National Championship game. He finished his collegiate athletic career with a season at Mississippi Valley State before spending his last season at Kentucky State. Pruitt was recently inducted into the Colbert County Sports Hall of Fame Class of 2024 for his outstanding athletic accomplishments in the county.On this episode Mike & Jason discuss the evolving landscape of college basketball, particularly the challenges inherent in building a competitive program amidst the increasing prevalence of player movement and the necessity for immediate results. As we delve into the intricacies of team dynamics and the necessity of adapting coaching strategies to the realities of contemporary recruiting, we examine the significance of maximizing the skill sets of players within the limited timeframe available. Our conversation also touches upon the importance of establishing a foundation of trust and rapport with players, which is essential for fostering a successful team environment. Ultimately, this episode seeks to illuminate the multifaceted nature of coaching in today's rapidly changing collegiate athletic landscape.Follow us on Twitter and Instagram @hoopheadspod for the latest updates on episodes, guests, and events from the Hoop Heads Pod.Make sure you're subscribed to the Hoop Heads Pod on Apple Podcasts or wherever you get your podcasts and while you're there please leave us a 5 star rating and review. Your ratings help your friends and coaching colleagues find the show. If you really love what you're hearing recommend the Hoop Heads Pod to someone and get them to join you as a part of Hoop Heads Nation.Take some notes as you listen to this episode with Jason Pruitt, Women's Basketball Associate Head Coach at Indiana State University.Website - https://gosycamores.com/sports/womens-basketballEmail - Jason.Pruitt@indstate.eduTwitter/X - @CoachjkpruittVisit our Sponsors!Dr. Dish BasketballA Perfect Gift To Your Team for the Holidays! Score Big on Dr. Dish Basketball's End of Year Sale and give your team the gift of extra, more efficient reps this season!

Santiago and David discuss the innovative “five quiz” model – an educational framework designed to improve student learning outcomes. Conceived during the pandemic, this model includes five types of quizzes: prerequisites, instructional, mastery, testing, and extension quizzes. Santiago and David explore how this framework, originally conceptualised for online courses, addresses various educational contexts and learning needs, from low-resource environments to high-resource institutions like Caltech.

Murtaza Hussain is a reporter for Drop Site News, which has brokenimportant stories based on recently obtained Epstein emails. Hussainreports that Epstein had an “extensive relationship with Israeliintelligence, U.S. intelligence and the intelligence agencies of othercountries, as well... He was a dealmaker and a fixer at a very, veryelite level.”Links:Drop Site News series on Epstein and Israelhttps://www.dropsitenews.com/s/epstein-and-israelFormer Israeli spy Ari Ben Menashe on Jeffrey Epsteinhttps://x.com/hsu_steve/status/1994046737040712144(01:08) - Introduction (02:20) - The Mission of Drop Site News (06:00) - Epstein Emails (15:28) - Epstein connections and elite power (35:48) - Epstein and intel agencies (39:54) - Ari Ben Menashe and the Iran Contra Affair (42:21) - Media Censorship and Political Implications (47:33) - The Future of Epstein Investigations –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

After graduating from Caltech with a degree in physics, Scott Sperling pursued computer science and ended up working in rocket science. He’s also been a Christian for decades and has applied his analytical mind to Bible study, especially on his website ScriptureStudies.com. In this interview I ask him about his paper, “A Hypothesis for the Mechanism of Bodily Resurrection” in which he explains how God can raise the dead on the basis of DNA and the neural connectome. He does not see any need for the existence of an immaterial soul or dualism to account for biblical resurrection.   Listen on Spotify   Listen on Apple Podcasts —— Links —— See Scott Sperling’s studies at his website where you can also download his paper. Support Restitutio by donating here Join our Facebook group, follow on X @RestitutioSF or Instagram @Sean.P.Finnegan Leave a 90 second voice message via SpeakPipe with questions or comments and we may play it out on the air Who is Sean Finnegan?  Read his bio here Get Finnegan’s book, Kingdom Journey to learn about God’s kingdom coming on earth as well as the story of how Christianity lost this pearl of great price. Get the transcript of this episode Intro music: Good Vibes by MBB Attribution-ShareAlike 3.0 Unported (CC BY-SA 3.0) Free Download / Stream: Music promoted by Audio Library.

Queridos Curiosinautas, hoy tenemos un episodio ENORME

Were you inspired by "Star Trek" (or one of its innumerable spinoffs) as a young person? We know we were, so it was a pleasure to invite Glen Swanson, author of the new Star Trek history book "Inspired Enterprise" onto the show. We've all heard lore about the original series, but Swanson, who was previously the Chief Historian at the Johnson Space Center, used his prodigious skills to perform a deep dive into the topic. From Gene Roddenberry's original inspiration to working with Caltech, the RAND Corporation, and NASA; and on to the design of the good ship Enterprise itself (and the very popular AMT models that followed), this book provides everything you need to know to be a certified Trekker. Headlines: Comet 3I Atlas confirmed as a comet, not a spacecraft & NASA releases new images and details of the comet SpaceX's Starship Version 3 booster suffers damage during test Uranus reaches yearly opposition—best viewing opportunity Main Topic: The Real Inspirations Behind Star Trek Glenn Swanson shares career highlights as a NASA historian and magazine founder How Gene Roddenberry's background and influences shaped Star Trek NASA's direct involvement and technical guidance for Star Trek's creators The significant role of the aerospace industry, Rand Corporation, and real-world science in Star Trek's development The story behind NASA and the Smithsonian Enterprise shooting model connections AMT's plastic model kits fueled fan obsession and supported the show's visuals Influences from movies like Robinson Crusoe on Mars and Forbidden Planet Space Station K7 design's origins traced to NASA and Douglas Aircraft concepts Star Trek's impact on inspiring real-life astronauts and the space community Glenn Swanson's book, "Inspired Enterprise," and how you can get a signed copy Hosts: Rod Pyle and Tariq Malik Guest: Glen Swanson Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit

Today we've got writer and publisher Dennis Mallonee, who moved from CalTech economics to #comics by pitching story ideas to Bill Mantlo and helping develop the Official Handbook of the Marvel Universe with Rick Hoberg. Dennis recounts launching The Champions at a 1985 SDCC panel, first publishing through Eclipse, and then forming his own imprint that evolved into Heroic Publishing. We dig into the complicated licensing history with Hero Games, the disputes over tone and pinup art that led to revoked rights and renamed characters (Marksman → Huntsman, Foxbat → Flying Fox), and the 1988 ruling confirming Marvel had abandoned the Champions trademark. Dennis also touches on publishing 100+ comics, his 2009–2012 Flare newspaper strip, and building a unique #superhero universe.You can follow Dennis and his Heroic exploits on his site, heroicmultiverse.com, on X @heroicpublish, and on his own YouTube interview show, The Heroic Voice.Support the show___________________Check out video versions of this and other episodes on YouTube: youtube.com/dollarbinbandits!If you like this podcast, please rate, review, and subscribe on Apple Podcasts or wherever you found this episode. And if you really like this podcast, become a member of the Dollar Bin Boosters on Patreon: patreon.com/DollarBinBoosters.You can follow us @dollarbinbandits on Facebook, Instagram, and Bluesky, or @DBBandits on X. You can email us at dollarbinbandits@gmail.com.___________________Dollar Bin Bandits is the official podcast of TwoMorrows Publishing. Check out their fine publications at twomorrows.com. ___________________ Thank you to Sam Fonseca for our theme music, Sean McMillan for our graphics, and Pat McGrath for our logo.

Were you inspired by "Star Trek" (or one of its innumerable spinoffs) as a young person? We know we were, so it was a pleasure to invite Glen Swanson, author of the new Star Trek history book "Inspired Enterprise" onto the show. We've all heard lore about the original series, but Swanson, who was previously the Chief Historian at the Johnson Space Center, used his prodigious skills to perform a deep dive into the topic. From Gene Roddenberry's original inspiration to working with Caltech, the RAND Corporation, and NASA; and on to the design of the good ship Enterprise itself (and the very popular AMT models that followed), this book provides everything you need to know to be a certified Trekker. Headlines: Comet 3I Atlas confirmed as a comet, not a spacecraft & NASA releases new images and details of the comet SpaceX's Starship Version 3 booster suffers damage during test Uranus reaches yearly opposition—best viewing opportunity Main Topic: The Real Inspirations Behind Star Trek Glenn Swanson shares career highlights as a NASA historian and magazine founder How Gene Roddenberry's background and influences shaped Star Trek NASA's direct involvement and technical guidance for Star Trek's creators The significant role of the aerospace industry, Rand Corporation, and real-world science in Star Trek's development The story behind NASA and the Smithsonian Enterprise shooting model connections AMT's plastic model kits fueled fan obsession and supported the show's visuals Influences from movies like Robinson Crusoe on Mars and Forbidden Planet Space Station K7 design's origins traced to NASA and Douglas Aircraft concepts Star Trek's impact on inspiring real-life astronauts and the space community Glenn Swanson's book, "Inspired Enterprise," and how you can get a signed copy Hosts: Rod Pyle and Tariq Malik Guest: Glen Swanson Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit

Were you inspired by "Star Trek" (or one of its innumerable spinoffs) as a young person? We know we were, so it was a pleasure to invite Glen Swanson, author of the new Star Trek history book "Inspired Enterprise" onto the show. We've all heard lore about the original series, but Swanson, who was previously the Chief Historian at the Johnson Space Center, used his prodigious skills to perform a deep dive into the topic. From Gene Roddenberry's original inspiration to working with Caltech, the RAND Corporation, and NASA; and on to the design of the good ship Enterprise itself (and the very popular AMT models that followed), this book provides everything you need to know to be a certified Trekker. Headlines: Comet 3I Atlas confirmed as a comet, not a spacecraft & NASA releases new images and details of the comet SpaceX's Starship Version 3 booster suffers damage during test Uranus reaches yearly opposition—best viewing opportunity Main Topic: The Real Inspirations Behind Star Trek Glenn Swanson shares career highlights as a NASA historian and magazine founder How Gene Roddenberry's background and influences shaped Star Trek NASA's direct involvement and technical guidance for Star Trek's creators The significant role of the aerospace industry, Rand Corporation, and real-world science in Star Trek's development The story behind NASA and the Smithsonian Enterprise shooting model connections AMT's plastic model kits fueled fan obsession and supported the show's visuals Influences from movies like Robinson Crusoe on Mars and Forbidden Planet Space Station K7 design's origins traced to NASA and Douglas Aircraft concepts Star Trek's impact on inspiring real-life astronauts and the space community Glenn Swanson's book, "Inspired Enterprise," and how you can get a signed copy Hosts: Rod Pyle and Tariq Malik Guest: Glen Swanson Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit

Were you inspired by "Star Trek" (or one of its innumerable spinoffs) as a young person? We know we were, so it was a pleasure to invite Glen Swanson, author of the new Star Trek history book "Inspired Enterprise" onto the show. We've all heard lore about the original series, but Swanson, who was previously the Chief Historian at the Johnson Space Center, used his prodigious skills to perform a deep dive into the topic. From Gene Roddenberry's original inspiration to working with Caltech, the RAND Corporation, and NASA; and on to the design of the good ship Enterprise itself (and the very popular AMT models that followed), this book provides everything you need to know to be a certified Trekker. Headlines: Comet 3I Atlas confirmed as a comet, not a spacecraft & NASA releases new images and details of the comet SpaceX's Starship Version 3 booster suffers damage during test Uranus reaches yearly opposition—best viewing opportunity Main Topic: The Real Inspirations Behind Star Trek Glenn Swanson shares career highlights as a NASA historian and magazine founder How Gene Roddenberry's background and influences shaped Star Trek NASA's direct involvement and technical guidance for Star Trek's creators The significant role of the aerospace industry, Rand Corporation, and real-world science in Star Trek's development The story behind NASA and the Smithsonian Enterprise shooting model connections AMT's plastic model kits fueled fan obsession and supported the show's visuals Influences from movies like Robinson Crusoe on Mars and Forbidden Planet Space Station K7 design's origins traced to NASA and Douglas Aircraft concepts Star Trek's impact on inspiring real-life astronauts and the space community Glenn Swanson's book, "Inspired Enterprise," and how you can get a signed copy Hosts: Rod Pyle and Tariq Malik Guest: Glen Swanson Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit

Jian Lian is an expert on China's political economy, industrial development, and technological development. He graduated from Peking University with a bachelor's and master's degree in economics. Starting out as an industry analyst at a Chinese investment bank, he participated in the "Made in China 2025" initiative as a Chinese venture capitalist, working for a state-owned fund. He is the author of "The Truth About Capital" 资本的真相 (2016), which contains major predictions about technology, economy, and society in China, most of which have since come true.Jian and Steve discuss the origins of the industrial party movement (discussed in an earlier episode with Kyle Chan), which culminated in the "industrial maximalism" view of development adopted by the PRC government. They also discuss the development of supply chains in China, and the role that US sanctions had in accelerating the Chinese semiconductor industry.Kyle Chan episode:https://www.manifold1.com/episodes/kyle-chan-on-the-future-of-us-china-competition-94Chinese industrial maximalism: https://www.high-capacity.com/p/chinese-industrial-maximalism(00:00) - Introduction (00:49) - Jian Gaokao score was 23rd in all of Fujian = Econ at Beida, not Genomics! (05:21) - China's Industrial Policy and Innovation (24:19) - Domestic supply chain strategy; How Huawei became a national champion due to US sanctions (34:13) - Venture Capital in China (36:13) - Hard Tech Investments (37:40) - Regulations of Tech Giants (44:28) - Future of China Technological Development –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU.Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

Pri Narang likes to go fast. It's no surprise, then, that she's sprinting toward the very edge of what's possible. While most are currently navigating an AI conversation, Pri — a Caltech-trained quantum physicist, award-winning professor, and U.S. Science Envoy — is pioneering the quantum frontier to solve humanity's most pressing challenges. In this episode, she and Ryan unpack “quantum theory” including what it takes to lead when the roadmap doesn't exist. Pri also shares how she equips teams to solve problems no one's ever cracked, what her endurance training has taught her about resilience, and why the emotional journey of discovery is just as important as the science. This is a conversation that spans research, policy, purpose, and the power of going full speed into the unknown.

Dr. John Eiler is the Robert P. Sharp Professor of Geology and Geochemistry, as well as the Ted and Ginger Jenkins Leadership Chair of the Division of Geological and Planetary Sciences at Caltech. In this episode, John discusses his career, his research examining the molecular structure of isotopes, and how the approach that he and his collaborators have developed is relevant for the anti-doping community. He goes into detail on a recent PCC-funded research project investigating the use of molecular isotopic structure as a tool for doping forensics, their promising new results, and the impacts that this work could have to advance clean sport.

In this episode, ARK's Cathie Wood and Brett Winton sit down with Sean McClain, Founder and CEO of AbSci, to explore how generative AI is reshaping drug discovery, development timelines, and clinical costs. Sean walks through real-world examples of AI-designed antibodies—such as AbSci's breakthrough HIV antibody and a regenerative treatment for hair loss—and explains how these platforms are helping unlock previously “undruggable” biology.They discuss AbSci's Phase 2-ready hair growth antibody (BS201), the company's partnerships with Caltech and AMD, and why the FDA's evolving embrace of AI could accelerate the end of animal testing. The conversation closes with a forward-looking discussion on the role of regenerative medicine in longevity—and why AI drug discovery might just pull biotech out of its multi-year bear market.Key Points From This Episode:(00:00:00) How AbSci uses generative AI to design antibodies from scratch(00:02:42) HIV, ion channels, and the promise of targeting "undruggable" biology(00:06:28) AbSci's BS201 drug for hair regrowth: mechanism, speed, and cost advantages(00:13:20) Clinical timeline: From concept to Phase 2 readout in 3.5 years(00:15:34) Bringing costs down: $100–150M vs. the industry average of $2.4B(00:17:36) Why AI enables “keys designed for specific locks” in drug targeting(00:22:58) What AbSci's models are trained on—and how prompts work in drug inference(00:25:32) The future of clinical testing: AI replacing animal models(00:36:43) Sarcopenia, strength loss, and regenerative approaches to aging(00:48:10) BS201 as a long-acting pulse therapy—and how it compares to transplants

In this episode we explore the most classical topic from Game Theory – equilibrium analysis. Our guest Colin Camerer shares insights on the game LUPI ('lowest unique positive integer'). We first discuss the actual mathematical equilibrium analysis and then dive into real life: results from a Swedish game show in which the game was played in a lottery format. Colin also compares the results from the game show with a study of the same game in a controlled lab environment. We finish the episode by deep-diving into level-k reasoning and Colin shares an example based on the role of published movie reviews.   Colin Camerer is the Robert Kirby Professor of Behavioral Economics at Caltech. His research interests include decisions, games, and markets.

Scott Horton is the author of Provoked: How Washington Started the New Cold War with Russia and the Catastrophe in Ukraine. Horton is a libertarian and anti-war activist. He and Steve discuss the Russia Hoax and its connection to American foreign policy, in light of new evidence that has emerged since the first Trump term.Scott's book: https://www.amazon.com/Provoked-Washington-Started-Catastrophe-Ukraine/dp/1733647376X handle: @scotthortonshow(00:00) - Scott Horton on the Russia Hoax and Ukraine War – #98 (01:49) - Scott Horton's Political Journey (04:55) - The State of Public Awareness and Media (11:42) - Russiagate and the Indictment of James Comey (43:13) - Perjury and Obstruction Charges: The Virginia Trial Dilemma (43:51) - The Durham Investigation: Unveiling Corruption (46:28) - Post-Durham Report Revelations (59:04) - Ukraine Conflict: Provoked or Unprovoked? –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU.Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

Host Dave Schlom visits with brand new MacArthur Fellowship award winner Kareem El-Badry, an astrophysicist at the California Institute of Technology in Pasadena.

What's at stake in climate modelling? Professor Tapio Schneider, CalTech, discusses how computational science improves understanding of tail risks and extreme events; why small-scale processes are critical for accurate models; and how finance can better integrate climate data into investments.

Lin Yang is a professor of computer science at UCLA. Recently, he and his collaborator built an AI pipeline using commercial models such as Gemini, ChatGPT, and Grok that performed at the gold medal level on International Mathematics Olympiad problems. Steve and Lin discuss this research, which relies on "verifier-refiner" LLM instances and large token budgets to reliably solve difficult problems. They discuss how these methods can be used to advance AI for scientific research, legal analysis, and complex document processing.https://github.com/lyang36/IMO25/blob/main/IMO25.pdfhttps://x.com/hsu_steve/status/1948189075707469942Chapter markers:(00:00) - AIs Win Math Olympiad Gold: Prof. Lin Yang (UCLA) – #97 (00:57) - Prof. Lin Yang, UCLA (04:27) - Journey from Physics to Computer Science: 2 PhDs (11:15) - Transition to AI from Theoretical CS (13:16) - AI Pipeline Math Olympiad: Gold Medal! (28:23) - Probability Amplification (29:00) - Applications in Industry and Legal Analysis (29:58) - Challenges in Model Reasoning and Verification (33:23) - Future of AI in Scientific Research and AGI Speculations –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU.Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

Zixuan Li is Director of Product and genAI Strategy at Z.ai. He was educated at Renmin and Tsinghua University in China, and at MIT and Carnegie Mellon. Z.ai has released frontier open source LLMs but is largely unknown in the West except among AI experts. Steve and Zixuan discuss the AI race from the perspective of a startup in Beijing.https://chat.z.ai/Follow Z.AI on X: @Zai_orgChapter markers:(00:00) - Introduction and Guest Background (05:14) - Z.ai's Evolution and Challenges (10:37) - AI Model Comparison and Industry Insights (34:04) - Pragmatic Views on AGI in China (35:51) - Specialized Models and Scientific Contributions (39:02) - AI Chips and Model Training in PRC (50:54) - Open Source AI and Future Predictions –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU.Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

Quantum Milestone, Microsoft Account Mandate, AI Energy Surge, and Gen AI in Marketing In this episode, host Jim Love covers groundbreaking advancements and significant changes in the tech world. Topics include Caltech's achievement of a 6,100 qubit quantum processor operating at room temperature, Microsoft's decision to require cloud sign-ins for Windows 11 users, and projections of a tenfold surge in power demand from AI data centers by 2030. Additionally, the episode discusses a survey indicating that 85% of marketing teams are now utilizing generative AI, up from 75% last year, and highlights the rapid, extensive effects of AI on marketing practices. 00:00 Quantum Milestone: 6,100 Qubits at Room Temperature 02:57 Microsoft Ends Local Windows Accounts 04:26 AI's Growing Power Demand 06:34 Generative AI Revolution in Marketing 08:37 Conclusion and Farewell

Matilde Marcolli is a computational linguist and mathematical physicist currently serving as Robert F. Christy Professor of Mathematics and Computing and Mathematical Sciences at Caltech. Her latest book is Mathematical Structure of Syntactic Merge: An Algebraic Model for Generative Linguistics with Noam Chomsky and Robert C. Berwick.ReferencesFrancesco Cirillo, "L'autonomia nomade." Gli autonomi: La autonomia operaia meridionale—Basiclica, Puglia, Calabria, Sicilia, part 3. eds Antonio Bove, Francesco Festa. DeriveApprodi, 2022.Oscar Greco, "L'Autonomia nel Sud. Affinità e divergenze tra i movimenti e l'autonomia calabrese." Gli autonomi: La autonomia operaia meridionale—Basiclica, Puglia, Calabria, Sicilia, part 3. eds Antonio Bove, Francesco Festa. DeriveApprodi, 2022.Adriano Maini, "Si strutturano nuove modalità di protesta quali assemblee, conferenze, dibattiti, sit-in, commissioni di lavoro," Collasgarba, January 5, 2023.David P. Palazzo. The "Social Factory" In Postwar Italian Radical Thought From Operaismo To Autonomia. Dissertation. State University of New York, 2014.Fabio Papalia. Il Sessantotto italiano nella dinamica delle occupazioni e dei cortei: un confronto tra i movimenti studenteschi di Torino, Milano e Roma. Dissertation. Università degli studi Roma Tre, 2011.Paolo Perri, "Per un pugno di riviste? Il blitz all'Università della Calabria." Gli autonomi: La autonomia operaia meridionale—Basiclica, Puglia, Calabria, Sicilia, part 3. eds Antonio Bove, Francesco Festa. DeriveApprodi, 2022.Franco Piperno, Lo spettacolo cosmico. Scrivere il cielo: lezioni di astronomia visiva. DeriveApprodi, 2007.Franco Piperno, "Conversazione in Calabria." Gli autonomi: La autonomia operaia meridionale, part 1. eds Antonio Bove, Francesco Festa. DeriveApprodi, 2022.Franco Piperno, "⁠AUTONOMIA POSSIBILE, VALORE D'USO, LAVORO NON-OPERAIO⁠." Metropoli, Rome, 1978.Franco Piperno and Francesco Raparelli, "La rivolta del sapere," Dinamo Press, June 27, 2018. Potere Operaio. "Alle avanguardie per il partito," 1970.Marco Scavino. Potere operaio: La storia. La teoria. Vol. 1. Roma: Derive Approdi, 2018.Steve Wright. The Weight of the Printed Word: Text, Context and Militancy in Operaismo. Leiden: Brill, 2021.

Tom is a fascinating man. He's shot lasers at the moon and measured their reflection. After studying astrophysics at Cal Tech he taught at UCSD for years. But there came a point where his awareness of the destructiveness of the machine made it impossible to keep making adjustments to its smooth functioning. Unlike many people confronted with that contradiction, Tom walked away, choosing freedom of thought over financial stability and ego gratification. This is the first part of what I hope will be an on-going conversation. Part two is coming next week.You can read Tom's thoughts at his newsletter, called Do the Math.Here's a taste of our conversation. If you prefer to see/hear the whole thing, here's a link to the full video.Intro music “Brightside of the Sun,” by Basin and Range. “Whiter Shade of Pale,” performed by Steve Winwood and Carlos Santana. Outro: “Smoke Alarm,” by Carsie Blanton.If you buy from Amazon, my link is here. (You can click on it once, then bookmark that as your go-to Amazon link so it'll always work.)Buy some merch from my mom here.Find other Tangentialistas around the world! This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit chrisryan.substack.com/subscribe

On University of Southern California Dornsife Week: We're still seeking to better understand dark matter in our universe. Vera Glusevic, associate professor of physics and astronomy, examines one way to do so. Vera received her B.Sc. from University of Belgrade (Serbia) in 2007, and her Ph.D. from Caltech in 2013. After completing a postdoctoral fellowship […]

Synopsis: When biotech meets bold partnerships, new models of innovation emerge. In this episode of the Biotech 2050 Podcast, host Rahul Chaturvedi welcomes Paul Biondi, Managing Partner at Flagship Pioneering, and Uli Stilz, Vice President, R&D External Innovation Partners at Novo Nordisk, to explore the power of co-creation. Together, they unpack how Flagship's pioneering medicines model and Novo's Bio Innovation Hub intersect to accelerate breakthroughs in obesity, diabetes, and cardiometabolic diseases. They share lessons on building trust, navigating crises, and structuring alliances that go beyond transactions into enduring innovation ecosystems. From human disease atlases to new frameworks for agile collaboration, this episode offers a rare behind-the-scenes look at how pharma and biotech can partner differently—turning complexity into transformative therapies. Biography: Paul Biondi is a Managing Partner at Flagship Pioneering, leading Flagship's product and partnering capabilities, including Pioneering Medicines, Partnering, and Pipeline and Product Innovation. In this role, Paul oversees Pioneering Medicines, Flagship's in-house drug discovery and development unit, as well as therapeutic partnering and business development efforts for the Flagship ecosystem, including driving broad institution-wide Innovation Supply Chain partnerships with biopharma companies to jointly conceive and create innovative products. Paul also works with Flagship company CEOs and their teams to achieve the best attainable value for each company, guiding them in their pipeline strategy, product concepts, R&D execution, and partnering approach. He serves on the boards of Flagship-founded companies, including Tessera Technologies (NASDAQ: TSRA) and Valo Health. Paul Biondi is Managing Partner at Flagship Pioneering, joining after 17 years at Bristol-Myers Squibb (BMS), where he served as SVP of Strategy & Business Development and held leadership roles in R&D. He previously spent nine years at Mercer Management Consulting. Paul earned his MBA from the Kellogg School of Management at Northwestern University and his B.A. from Dartmouth College. Uli Stilz is Corporate Vice President, R&D External Innovation Partners, External & Exploratory Innovation (E2I) at Novo Nordisk., based in Boston. He leads a global R&D team that builds creative partnerships with biotech, venture capital, academia, and research hospitals to co-create next-generation therapeutics in cardiometabolic and rare diseases. Building on the success of the Novo Nordisk Bio Innovation Hub, Uli and the E2I team drive an externally anchored portfolio of collaborations that stimulate global innovation ecosystems and advance Novo Nordisk's pipeline. Uli Stilz earned his Master's in Organic Chemistry from ETH Zürich and a Ph.D. in Biochemistry from the Max-Planck-Institute of Biochemistry in Martinsried, followed by postdoctoral research at Caltech. He began his industry career at Hoechst AG and later Sanofi, where he became Associate VP of the Innovation Unit in the Diabetes Division. Over two decades, he contributed to more than 60 preclinical and clinical drug candidates in cardiometabolic, immunology, and oncology. From 2012–2014, he served as President of the European Federation for Medicinal Chemistry. In 2014, Uli joined Novo Nordisk in Copenhagen and in 2019 moved to Boston to establish and lead the Bio Innovation Hub, now the External & Exploratory Innovation (E2I) organization. He also serves as Adjunct Professor at the University of Frankfurt, sits on editorial and scientific advisory boards, and holds board roles at the Kendall Square Association and Gensaic, while advising the aMoon Fund.

In this episode of ACM ByteCast, Bruke Kifle hosts ACM Distinguished Member Cecilia Aragon, Professor in the Department of Human Centered Design and Engineering and Director of the Human-Centered Data Science Lab at the University of Washington (UW). She is the co-inventor (with Raimund Seidel) of the treap data structure, a binary search tree in which each node has both a key and a priority. She is also known for her work in data-intensive science and visual analytics of very large data sets, for which she received the Presidential Early Career Award for Scientists and Engineers (PECASE) in 2008. Prior to her appointment at UW, she was a computer scientist and data scientist at Lawrence Berkeley National Laboratory and NASA Ames Research Center, and before that, an airshow and test pilot, entrepreneur, and member of the United States Aerobatic Team. She is a co-founder of Latinas in Computing. Cecilia shares her journey into computing, starting as a math major at Caltech with a love of the Lisp programming language, to vital work innovating data structures, visual analytics tools for astronomy (Sunfall), and augmented reality systems for aviation. She highlights the importance of making data science more human-centered and inclusive practices in design. Cecilia discusses her passion for broadening participation in computing for young people, a mission made more personal when she realized she was the first Latina full professor in the College of Engineering at UW. She also talks about Viata, a startup she co-founded with her son, applying visualization research from her lab to help people solve everyday travel planning challenges. We want to hear from you!

- "World Models” aim for the next big thing in AI - Microsoft's $3.3B datacenter, with a $4B one to Follow - OpenAI talks central-park-sized datacenter, times 13 - In-Chip ‘Microfluidics' cooling - Caltech tames 6,100 neutral atom qubits with 12,000 optical tweezers [audio mp3="https://orionx.net/wp-content/uploads/2025/09/HPCNB_20250929.mp3"][/audio] The post HPC News Bytes – 20250929 appeared first on OrionX.net.

3/4: This file details Steady State theory creation, Hoyle's element theory, coining "Big Bang," and CMB discovery. Fred Hoyle, Bondi, and Gold conceived Steady State theory after watching The Dead of Night (1946/47). Their model proposed continuous creation via quantum uncertainty. Hoyle solved carbon formation: two helium atoms form unstable Beryllium-8, briefly uniting with third helium to forge Carbon-12. Hoyle predicted carbon's specific energy level, which Willie Fowler at Caltech verified. Hoyle coined "Big Bang" derisively on BBC radio, mocking single-blast creation. Gamow and Ralph Alpher called initial substance "ylem." Hoyle and Gamow met in 1956 La Jolla, discussing universe temperature; Hoyle believed near 0 Kelvin, Gamow preferred 10 Kelvin. In 1964, Penzias and Wilson at Bell Labs accidentally discovered persistent background radiation—the Cosmic Microwave Background—proving the Big Bang that Gamow sought. Flashes of Creation: George Gamow, Fred Hoyle, and the Great Big Bang Debate, by Paul Halpern

Dr. Konstantin Batygin, professor of Planetary Science at Caltech, made a joke that turned out to be true. In 2014, another Caltech professor, Mike Brown, brought an intriguing research paper to Batygin's attention. The paper described a peculiar planetary alignment in the outer solar system. While developing theoretical models to explain the paper's assertions, Brown and Batygin had a running gag, "We were like, okay, as a joke, let's put a planet in the outer solar system just to see what would happen." In this episode of Looking Up, Dean Regas chats with Dr. Batygin and gets the full story.

Zócalo Public Square presents two back-to-back panels moderated by Zócalo's California columnist Joe Mathews to ask: How exceptional do we want California to be? The first panel features expert voices in fields shaping California's identity: business advocate and public affairs specialist Brooke Armour Spiegel, Caltech astrophysicist Konstantin Batygin, and immigrant rights advocate Yliana Johansen-Méndez. The second panel features youth leaders who are inheriting the state: trans rights organizer, budget advocacy and policy expert Michaé De La Cuadra, community organizer and housing justice advocate Aidan Lin-Tostado, and Tongva, Chumash, and Xicano artist and environmental advocate Isaac Michael Ybarra. This program is presented with generous support from Latino Community Foundation, the Karsh Family Foundation, and Snap Foundation. Timestamps: 00:00:00 - Intros 00:03:18 - Panel 1 (Expert Voices): Brooke Armour Spiegel, Konstantin Batygin, Yliana Johansen-Méndez 00:43:02 - Panel 2 (Youth Leaders): Michaé De La Cuadra, Aidan Lin-Tostado, Isaac Michael Ybarra Visit www.zocalopublicsquare.org/ for more programs and essays in the series. Follow Zócalo on X: x.com/thepublicsquare Instagram: www.instagram.com/thepublicsquare/ Facebook: www.facebook.com/zocalopublicsquare LinkedIn: www.linkedin.com/company/z-calo-public-square/

Bio: Jim Fruchterman is a leading social entrepreneur, author, MacArthur Fellow, recipient of the Skoll Award for Social Entrepreneurship, and Distinguished Alumnus of Caltech. After starting two successful for-profit AI companies, he went on to found Benetech, the award-winning tech nonprofit, building tools for people with disabilities and human rights defenders document and analyze abuses.  His current nonprofit projects at Tech Matters include Aselo, a shared modern contact center for the crisis response field; Terraso, software for the people on the front line of the climate crisis; and the Better Deal for Data, a data governance reform movement.    This episode is sponsored by the coaching company of the host, Paul Zelizer. Consider a Strategy Session if you can use support growing your impact business. Resources mentioned in this episode include: Benetech site Bookshare site Aselo site Terrasoul site Tech for Good book Paul's Strategy Sessions Pitch an Awarepreneurs episode

In this episode of SparX, Mukesh Bansal speaks with Rana Adhikari, experimental physicist at Caltech and leading voice in gravitational-wave research. From doubting Einstein as a student to helping build the LIGO detectors that confirmed his theories, Rana has been honoured with the Breakthrough Prize, Gruber Prize, and the New Horizons in Physics Prize.They dive into:What gravitational waves really are, and how LIGO measures distortions smaller than an atom.The story behind LIGO's breakthrough detections which is now catching 2–3 black hole mergers every week.Why LIGO-India, now approved and funded, could be the world's most precise detector and even test Einstein's theory of relativity itself.The cutting-edge role of quantum entanglement and AI in pushing measurement beyond classical limits.Building a thriving science ecosystem in India focused on mentorship, risk-taking, and the path to future Nobel Prizes.Rana also shares his personal journey from tinkering as an auto mechanic in Florida, to becoming one of the world's foremost experimental physicists, and now working closely with India to bring world-class science infrastructure to life.If you're curious about black holes, the true nature of reality, or India's chance to lead in fundamental science, this conversation is a must-watch.

In this episode you will hear:   Mark shares two admissions tips from students and he discusses Cal Tech's new test score policy. Lisa leads a panel discussion of five parents, all listeners of YCBK. The parents open up and reveal the pressure their student faces at school to go to an elite college.   Here is a link for our new YCBK listener survey so you can take the survey:   Speakpipe.com/YCBK is our method if you want to ask a question and we will be prioritizing all questions sent in via Speakpipe. Unfortunately, we will NOT answer questions on the podcast anymore that are emailed in. If you want us to answer a question on the podcast, please use speakpipe.com/YCBK. We feel hearing from our listeners in their own voices adds to the community feel of our podcast.   You can also use this for many other purposes: 1) Send us constructive criticism about how we can improve our podcast 2) Share an encouraging word about something you like about an episode or the podcast in general 3) Share a topic or an article you would like us to address 4) Share a speaker you want us to interview 5) Leave positive feedback for one of our interviewees. We will send your verbal feedback directly to them and I can almost assure you, your positive feedback will make their day.   To sign up to receive Your College-Bound Kid PLUS, our new monthly admissions newsletter, delivered directly to your email once a month, just go to yourcollegeboundkid.com, and you will see the sign-up popup. We will include many of the hot topics being discussed on college campuses.   Check out our new blog. We write timely and insightful articles on college admissions:   On X for our podcast:   https://twitter.com/YCBKpodcast   1. To access our transcripts, click: https://yourcollegeboundkid.com/category/transcripts/ 2. Find the specific episode transcripts for the one you want to search and click the link 3. Find the magnifying glass icon in blue (search feature) and click it 4. Enter whatever word you want to search. I.e. Loans 5. Every word in that episode when the words loans are used, will be highlighted in yellow with a timestamps 6. Click the word highlighted in yellow and the player will play the episode from that starting point 7. You can also download the entire podcast as a transcript   We would be honored if you will pass this podcast episode on to others who you feel will benefit from the content in YCBK.   Please follow our podcast. It really helps us move up in Spotify and Apple's search feature so others can find our podcast.   If you enjoy our podcast, would you please do us a favor and share our podcast both verbally and on social media? We would be most grateful!   If you want to help more people find Your College-Bound Kid, please make sure you follow our podcast. You will also get instant notifications as soon as each episode goes live.   Check out the college admissions books Mark recommends:   Check out the college websites Mark recommends:   If you want to have some input about what you like and what you recommend, we change about our podcast, please complete our Podcast survey; here is the link:     If you want a college consultation with Mark just text Mark at 404-664-4340 or email Lisa at . All we ask is that you review their services and pricing on their website before the complimentary session; here is link to their services with transparent pricing: https://schoolmatch4u.com/services/compare-packages/  

Assistant Professor Mohammad Mirhosseini (Caltech EE/APh) explains how his group built a mechanical quantum memory that stores microwave-photon quantum states far longer than typical superconducting qubits, and why that matters for hybrid quantum architectures. The discussion covers microwave photons, phonons, optomechanics, coherence versus lifetime (T2 vs. T1), current speed bottlenecks, and implications for quantum transduction and error mechanisms. The discussion centers on a paper from Mirhosseini's paper from December of 2024 titled, “A mechanical quantum memory for microwave photons,” detailing strong coupling between a transmon and a long‑lived nanomechanical oscillator for storage and retrieval of nonclassical states.GuestMohammad Mirhosseini is an Assistant Professor of Electrical Engineering and Applied Physics at Caltech, where his group engineers hybrid superconducting–phononic–photonic systems at millikelvin temperatures for computing, communication, and sensing. He completed his PhD at the University of Rochester's Institute of Optics and was a postdoc in Oscar Painter's group at Caltech before starting his lab. His recent team effort demonstrates mechanical oscillators as compact, long‑lived quantum memories integrated with superconducting circuits.Key topicsWhat “microwave photons” are and how qubits emit/absorb single microwave photons in circuit QED analogously to atoms and optical photons.Why “memory” is missing in today's quantum processors and how a dedicated long‑lived storage element can complement fast but dissipative superconducting qubits.Optomechanics 101: mapping quantum states between electrical and mechanical degrees of freedom, with phonons as the quantized vibrational excitations.T1 vs. T2: demonstrated order‑of‑magnitude gains in lifetime (T1) and more modest current gains in coherence (T2), plus paths to mitigate dephasing.Present bottleneck: state conversion between qubit and oscillator is about 100× slower than native superconducting operations, with clear engineering avenues to speed up.Quantum transduction: leveraging the same mechanical intermediary to bridge microwave and optical domains for interconnects and networking.Two‑level system (TLS) defects: shared decoherence mechanisms across mechanical oscillators and superconducting circuits and why comparing both can illuminate materials limits.Why it mattersHybrid architectures that pair fast processors with long‑lived memories are a natural route to scaling, and mechanical oscillators offer lifetimes far exceeding conventional superconducting storage elements while remaining chip‑integrable.. Demonstrating nonclassical state storage and retrieval with strong qubit–mechanics coupling validates mechanical oscillators as practical quantum memories and sets the stage for on‑chip transduction. Overcoming current speed limits and dephasing would lower the overhead for synchronization, buffering, and possibly future fault‑tolerant protocols in superconducting platforms.Episode highlightsA clear explanation of microwave photons and how circuit QED lets qubits create and absorb them one by one.Mechanical memory concept: store quantum states as phonons in a gigahertz‑frequency nanomechanical oscillator and read them back later.Performance today: roughly 10–30× longer T1 than typical superconducting qubits with current T2 gains of a few×, alongside concrete strategies to extend T2.Speed trade‑off: present qubit–mechanics state transfer is ~100× slower than native superconducting gates, but device design and coupling improvements are underway.Roadmap: tighter coupling for in‑oscillator gates, microwave‑to‑optical conversion via the same mechanics, and probing TLS defects to inform both mechanical and superconducting coherence.

Lead in gasoline powered cars have killed more people than those that died in World War Two. That's the astonishing claim of David Obst who, in his new Saving Ourselves From Big Car, lays out a strategy to kick our self-destructive automobile addiction. The former investigative reporter, who worked with Seymour Hersh on the My Lai massacre story and represented Woodward and Bernstein for All the President's Men, argues that the auto industry suppressed knowledge about lead's deadly effects for 70 years. More controversially, Obst claims electric vehicles are no better due to the lead in batteries. The only safe future is one without cars, he insists, pointing to car-free communities like Tempe, Arizona and Taipei, Taiwan as models for breaking what he calls our addiction to automobiles.1. Lead in gasoline killed more people than World War II Obst claims that from 1927 to the 1990s, lead additives in gasoline caused more deaths globally than WWII, citing World Health Organization statistics - though interviewer Andrew Keen found this claim conspiratorial.2. Electric vehicles aren't the solution Surprisingly, Obst argues EVs are just as dangerous as gas cars because their batteries contain lead. He points to Tesla fires in the California Palisades spreading lead pollution as evidence of this ongoing problem.3. The auto industry suppressed the truth for 70 years The Ethel Corporation (formed by Standard Oil, DuPont, and GM) allegedly kept lead's deadly effects secret through lobbying and silencing critics, including exiling Caltech scientist Claire Patterson who tried to expose the danger.4. Americans are "addicted" to cars Inspired by his granddaughter telling him "you are the traffic," Obst argues we must treat car dependence like any other addiction - acknowledging that 30% of gasoline is burned just looking for parking spaces.5. Car-free communities are the only answer Obst profiles successful car-free zones from Tempe, Arizona (6,000 residents, no cars allowed) to Taipei's bicycle-centric system, arguing for gradual implementation of car-free neighborhoods rather than overnight transformation.Keen On America is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit keenon.substack.com/subscribe

BASILISK, the first esports organization dedicated to promoting science, has teamed up with The Planetary Society and Caltech’s Institute for Quantum Information and Matter to bring the banner of “Science Victory” to gamers around the world. Their roster includes world champions in StarCraft II, chess, Magic: The Gathering, and fighting games, all united by a shared mission to inspire the next generation of scientists. Joining us to talk about this unique collaboration is Kyle Hill, award-winning science communicator and BASILISK’s head of science education and outreach. Kyle shares how his career in science communication led him from YouTube into the world of professional gaming, where science and play are coming together in powerful new ways. Then, stick around for What’s Up with Bruce Betts, our chief scientist, as we share our favorite space-themed video games and a new random space fact. Discover more at: https://www.planetary.org/planetary-radio/2025-basiliskSee omnystudio.com/listener for privacy information.

Dr. Melanie Walker is a trained neurosurgeon who, in the late 1990s, served as a science advisor to Jeffrey Epstein. She reportedly met Epstein in the early 1990s and, in 1998, while completing post-doctoral work at Caltech, accepted that role—helping him identify and connect with academics whose work he might fund, thus facilitating his access to elite intellectual circles. Despite her advisory connection, Walker has not been accused of any wrongdoing or involvement in Epstein's criminal activities.In the 2000s, Walker transitioned into philanthropy and global development. She held significant roles at the Bill & Melinda Gates Foundation—including deputy director of special initiatives—and was later placed at the World Bank under a secondment arrangement, ultimately becoming Senior Adviser to the President and Director of the Delivery Unit. She also serves in leadership roles within health and development policy spheres, such as co‑chairing the World Economic Forum's Future Council on neuro-technology and brain science.To contact me:bobbycapucci@protonmail.comSource:https://www.thesun.co.uk/news/worldnews/10397210/prince-andrew-jeffrey-epstein-neurosurgeon-ranch/

Dr. Melanie Walker is a trained neurosurgeon who, in the late 1990s, served as a science advisor to Jeffrey Epstein. She reportedly met Epstein in the early 1990s and, in 1998, while completing post-doctoral work at Caltech, accepted that role—helping him identify and connect with academics whose work he might fund, thus facilitating his access to elite intellectual circles. Despite her advisory connection, Walker has not been accused of any wrongdoing or involvement in Epstein's criminal activities.In the 2000s, Walker transitioned into philanthropy and global development. She held significant roles at the Bill & Melinda Gates Foundation—including deputy director of special initiatives—and was later placed at the World Bank under a secondment arrangement, ultimately becoming Senior Adviser to the President and Director of the Delivery Unit. She also serves in leadership roles within health and development policy spheres, such as co‑chairing the World Economic Forum's Future Council on neuro-technology and brain science.To contact me:bobbycapucci@protonmail.comSource:https://www.thesun.co.uk/news/worldnews/10397210/prince-andrew-jeffrey-epstein-neurosurgeon-ranch/Become a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

In this episode of The Bulletin, producer Clarissa Moll talks with missiologist Todd Korpi about what AI reveals about being human. Associate producer Alexa Burke digs into artificial intelligence history with data science professor Jonathan Barlow, and Dr. Finny Kuruvilla shares the amazing advancements and ethical questions that AI in medical technology raises.  GO DEEPER WITH THE BULLETIN: -Join the conversation at our Substack. -Find us on YouTube. -Rate and review the show in Apple Podcasts. ABOUT THE GUESTS:   Todd Korpi is a Pentecostal missiologist, researcher, and writer. In addition to work consulting with churches on organizational effectiveness and missional engagement, he serves as lead researcher of the Digital Mission Consortia at the Wheaton College Billy Graham Center and as an adjunct instructor in mission and leadership at several institutions. Jonathan Barlow is associate director of the Data Science program at Mississippi State as well as an assistant teaching professor. Previously, Barlow was an associate director at NSPARC, a research center at Mississippi State University. With a background in industry and university research, Barlow has more than 25 years of experience in software development, data modeling, data-intensive applications, and data analysis. His research interests involve natural language processing and the ethics of artificial intelligence. Finny Kuruvilla holds an MD from Harvard Medical School, a PhD in Chemistry and Chemical Biology from Harvard University, a master's degree in Electrical Engineering and Computer Science from MIT, and a bachelor's degree from Caltech in Chemistry. He is the co-chief investment officer at Eventide Asset Management, LLC, a socially-responsible and values-based investing firm.   Views expressed in this podcast are intended for information purposes and do not constitute investment advice. Eventide does not provide tax, accounting, or legal advice. Eventide's values-based approach to investing may not produce desired results and could result in underperformance compared with other investments. There is no guarantee that any investment will achieve its objectives, generate positive returns, or avoid losses. ABOUT THE BULLETIN: The Bulletin is a twice-weekly politics and current events show from Christianity Today moderated by Clarissa Moll, with senior commentary from Russell Moore (Christianity Today's editor in chief) and Mike Cosper (director, CT Media). Each week, the show explores current events and breaking news and shares a Christian perspective on issues that are shaping our world. We also offer special one-on-one conversations with writers, artists, and thought leaders whose impact on the world brings important significance to a Christian worldview, like Bono, Sharon McMahon, Harrison Scott Key, Frank Bruni, and more.  The Bulletin listeners get 25 percent off CT. Go to https://orderct.com/THEBULLETIN to learn more. “The Bulletin” is a production of Christianity Today Producer: Clarissa Moll Associate Producer: Alexa Burke Editing and Mix: Kevin Morris Music: Dan Phelps Executive Producers: Erik Petrik and Mike Cosper Senior Producer: Matt Stevens Learn more about your ad choices. Visit podcastchoices.com/adchoices

Today Razib talks to repeat guest Steve Hsu about China, a topic with so many currently relevant dimensions gIven the PRC's clear emergence as an economic, military and political rival to the US. Hsu is a Caltech‑trained theoretical physicist who migrated from black holes to big data, co‑invented privacy tech at SafeWeb, helped found the biotech company Genomic Prediction, all while remaining a prominent public voice on genetics, intelligence and the future of human enhancement. He is also a professor of physics at Michigan State, and from 2012-2020 was vice president for research and graduate studies there. Razib and Hsu discuss whether China is innovating and how meanwhile American regulation and culture are stifling its domestic creativity. A proud Iowan, Hsu rebuts the notion that he is pro-China, seeing himself simply as a realist convinced that it is important to face the PRC head on and assess its strengths candidly. He and Razib talk about China's demographic headwinds. Hsu points out the reality of demographic inertia. The generation already born in the 21st century is an abundant young workforce who will power the nation's rise for the next 30-40 years; that disastrously plummeting fertility making headlines today is a concern post-dated for at least a generation down the road. They also discuss the quality of Chinese higher education, and the reality that the population today is far more educated than it was 25 years ago. Hsu also talks about possible cultural and biobehavioral differences between East Asians and Europeans, and addresses why South Asians seem to be better adapted to succeed in American corporate culture.

Many chronic health conditions—such as IBS, asthma, and autoimmune disorders—can be traced back to imbalances in the gut. Disruptions to the microbiome caused by antibiotics, poor diet, food sensitivities, and environmental exposures can lead to inflammation, malabsorption, and increased intestinal permeability (leaky gut). Addressing gut health through a structured Functional Medicine approach called the 5R's of gut repair—removing harmful triggers, replacing missing digestive factors, reinoculating with beneficial bacteria, repairing the gut lining, and rebalancing lifestyle factors—can restore balance and improve systemic health.  In this episode, I discuss, along with Dr. Elizabeth Boham and Raja Dhir, the Functional Medicine approach to healing the gut and why the gut is at the center of imbalances in the body, including many health conditions. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women's Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Raja Dhir is the co-founder and co-CEO of Seed Health, a microbiome science company developing innovative probiotics and living medicines to advance human and planetary health. He specializes in translating cutting-edge microbial research into impactful products and leads Seed Health's academic collaborations with institutions such as MIT, Harvard, Stanford, Caltech, and the NIH. Raja co-chairs Seed's Scientific Board alongside Dr. Jacques Ravel, guiding research across microbiology, immunology, genetics, and ecology. He also directs LUCA Biologics, a company focused on the vaginal microbiome and women's health, and oversees SeedLabs, which drives environmental initiatives. Through this work, Raja plays a key role in accelerating microbiome-based solutions from discovery to market. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: What Is Leaky Gut And How Can You Treat It?How to Select a Probiotic and the Future of the MicrobiomeHow To Do The 10-Day Detox