Podcasts about neurosci

Welcome to the podcast with Dr. Brendan McCarthy!   This episode takes you deep into the real-world practice of prescribing testosterone therapy for women. This is not a high-level overview—this is a nuts and bolts breakdown: ✅ Who it's for ✅ How it's dosed ✅ What labs to run ✅ What delivery methods are safest ✅ Why it's often done wrong—and how to get it right   With over 20 years of clinical experience, Dr. McCarthy shares the insights no seminar or textbook can offer, including the emotional and psychological challenges women face when beginning testosterone therapy, and the very real fears around side effects and community stigma.  

Welcome to the podcast with Dr. Brendan McCarthy!   In this episode we dive deep into one of the most misunderstood and debated topics in hormone health: testosterone replacement therapy (TRT) for women. You may have heard horror stories—or glowing reviews. But what's the truth? Dr. McCarthy discusses: - Why testosterone matters for women's health - How it affects brain chemistry, mood, bone density, and even breast tissue - Its role after estrogen-suppressing breast cancer treatments - The difference between safe and unsafe TRT - What your provider should be doing to monitor and manage it effectively   Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he's been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more.   Citations: Popma, Arne, et al. "Cortisol moderates the relationship between testosterone and aggression in delinquent male adolescents." Biological psychiatry 61.3 (2007): 405-411 Likhtik, E., Stujenske, J. M., Topiwala, M. A., Harris, A. Z. & Gordon, J. A. Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety. Nat. Neurosci. 17, 106–113 (2014). Brannon, Skylar M., et al. "Exogenous testosterone increases sensitivity to moral norms in moral dilemma judgements." Nature Human Behaviour 3.8 (2019): 856-866.. * M.H.M. Hutschemaekers, R.A. de Kleine, M.L. Davis, M. Kampman, J.A.J. Smits, K. Roelofs,Endogenous testosterone levels are predictive of symptom reduction with exposure therapy in social anxiety disorder,Psychoneuroendocrinology,Volume 115,2020,104612 Barel, E, Abu‐Shkara, R, Colodner, R, et al. Gonadal hormones modulate the HPA‐axis and the SNS in response to psychosocial stress. J Neuro Res. 2018; 96: 1388– 1397. https://doi.org/10.1002/jnr.24259 * Buades-Rotger, M., Engelke, C., Beyer, F. et al. Endogenous testosterone is associated with lower amygdala reactivity to angry faces and reduced aggressive behavior in healthy young women. Sci Rep 6, 38538 (2016). https://doi.org/10.1038/srep38538 Ando, Sebastiano, et al. "Breast cancer: from estrogen to androgen receptor." Molecular and cellular endocrinology193.1-2 (2002): 121-128. Somboonporn, Woraluk, and Susan R. Davis. "Testosterone effects on the breast: implications for testosterone therapy for women." Endocrine reviews 25.3 (2004): 374-388. Donovitz, Gary, and Mandy Cotten. "Breast cancer incidence reduction in women treated with subcutaneous testosterone: testosterone therapy and breast cancer incidence study." European journal of breast health 17.2 (2021): 150. Glaser, Rebecca L., Anne E. York, and Constantine Dimitrakakis. "Incidence of invasive breast cancer in women treated with testosterone implants: a prospective 10-year cohort study." BMC cancer 19.1 (2019): 1271.   Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next!   Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-...   -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com

Overwhelmed by the relentless grip of fear while navigating your role as a grandparent raising grandchildren? Fear not, you're not alone. Join Laura Brazan on 'Grandparents Raising Grandchildren: Nurturing Through Adversity' and explore the art of fearless living with Emmy Award-winning life coach, Rhonda Britten. Dive into powerful stories, tips, and insights that illuminate the path to overcoming fear, transforming it into strength. Through expert guidance from the Fearless Living Institute and practical strategies, redefine your relationship with fear and embrace a fearless mindset. Delve into the neuroscience of fear, kinship carSend us a textWe recognize the unique challenges and needs of grandparents raising their grandchildren. That's why we've teamed up with EggMed, a world-renowned practice management software developer, to create a tailored online platform that fosters a strong, supportive community, all within a HIPAA-secure, safe, and moderated environment.This program will provide a secure space for connection, support, and shared learning. You'll be able to connect with other grandparents, share your experiences, Owner, Broker, and Realtor at Team Eureka with National Parks Realty Forbes Global Properties—Sandi Hall is a beacon of trust and insight for both local and international clients. With a Graduate REALTOR® Institute designation and a feature in Forbes, underscore her commitment to excellence.Visit WelcomeHomeMontana.com today or call (406) 471-0749 and experience the difference an expert like Sandi can bring to your journey home. Big Heart Family Dentistry, led by Dr. Seth Hinckley. Their dedication goes beyond treating teeth; they empower healthier, happier lives through prevention and education. They use state-of-the-art technology and are deeply connected to the community, addressing every dental need with expertise and heart. Join us for "Fun Self-Care Tips" with Jeanette Yates! Discover how self-care doesn't have to be a chore. Jeanette will share her favorite creative and enjoyable strategies at the end of every episode. From playful activities to joyful mindfulness practices, you'll learn how to infuse fun into your daily routine while prioritizing your well-being. Tune in and start your journey to a more joyful and balanced self!Thank you for tuning into today's episode. It's been a journey of shared stories, insights, and invaluable advice from the heart of a community that knows the beauty and challenges of raising grandchildren. Your presence and engagement mean the world to us and to grandparents everywhere stepping up in ways they never imagined. Remember, you're not alone on this journey. For more resources, support, and stories, visit our website and follow us on our social media channels. If today's episode moved you, consider sharing it with someone who might find comfort and connection in our shared experiences. We look forward to bringing more stories and expert advice your way next week. Until then, take care of yourselves and each other.Want to be a guest on Grandparents Raising Grandchildren: Nurturing Through Adversity? Send Laura Brazan a message on PodMatch, here: https://www.podmatch.com/hostdetailpreview/grgLiked this episode? Share it and tag us on Facebook @GrandparentsRaisingGrandchilden Love the show? Leave a review and let us know! CONNECT WITH US: Website | Facebook

ReferencesJournal of Biological Chemistry 2013. 28.8 52 :37355-37364 Neuro Oncol . 2020 Mar5;22(3):333-344.Front. Cell. Neurosci., 2018 27 NovemberCell Metabolism 2016. Volume 23, Issue 2, Pages 303-314JBC in Press 2025. 10854. 4April. Mydland, B. 1989. "I will Take You Home" Grateful Deadhttps://open.spotify.com/track/1Q3AmIjEbPYemA6UkjUUu0?si=3301b3057df94e04Joel, B. 1979. "Until the Night"https://open.spotify.com/track/3UzWjLQVzCG60gwJdApLqI?si=c0a9ded856c941cdSimon, P. 1965. "April Come She Will"https://open.spotify.com/track/0djZ2ndRfAL69WYNra5jRC?si=da8581de131448b2Mozart, WA. 1787. et al. Symphony 25 K.183 in G minor , plus symphonies 28, and 29https://open.spotify.com/album/3qhUJTpkFjDeM49QidGMQb?si=iUpvUWNfSlyWGSzgvjDKLg

What can the history of science tell us about the world we live in today and where we might be headed tomorrow? To find out, Dr. Charles Liu and co-host Allen Liu welcome historian of science Rebecca Charbonneau, PhD from the American Institute of Physics and the National Radio Astronomy Observatory with expertise in radio astronomy and the search for extraterrestrial intelligence (SETI). This episode kicks off with Allen and Chuck talking about January's Lunar Occultation of Mars. You can see a photo taken by Chuck on our YouTube Community tab. And then it's time for today's joyfully cool cosmic thing: a recent paper in the Astrophysical Journal Letters confirming there are galaxies that were fully formed just 400 million years after The Big Bang. Chuck, who studies galactic evolution, tells us why this changes our understanding of galaxy formation. Rebecca talks about how new ideas can be controversial and how personalities, politics and cultures can impact the evolution of science. She brings up the current controversy in astronomy concerning the locations of terrestrial telescopes and the tension between scientific and cultural imperatives. She also recounts seeing people in Russia wearing NASA t-shirts and explains how NASA understood the importance of controlling the narrative, even inviting Norman Rockwell to popularize the space program. Our first question comes from Pablo P. on Patreon, who asks, “Can humanity be destroyed by AI powered by quantum computing?” Rebecca explains how during the Cold War, scientists on both sides engaged in “science diplomacy” that helped lower tensions. She applies this thinking to AI, pointing out that while a “Terminator-like” scenario is unlikely, public concern is causing the tech world to confront and grapple with real threats from AI like biases in hiring algorithms. Allen, a mathematician who writes about AI professionally, addresses whether AI powered by quantum computing is more dangerous than AI in general. Rebecca shares the terrifying story of a Soviet nuclear submarine and the US navy during the Cuban Missile Crisis that nearly started a nuclear war. The dissenting actions of a single officer named Vasily Arkhipov made the difference, and she wonders if AI would have made the same decision based on the available data. For our next question, we return to our Pablo P. from Patreon for his follow up: “How [do] we answer the question about whether or not we are engaging in self-destructive behavior?” Chuck and Rebecca discuss the confluence of astronomy and the military, and how the history of the SETI program highlights their shared concerns. You'll find out what the Drake Equation has to do with concepts like The Great Filter. Science, she reminds us, is a tool to try to get closer to the truth, but it's not always perfect in pointing out whether what we're doing is safe or potentially self-destructive. Then we turn to Rebecca's other big passion, art history and the window into the human experience that art provides. Charles brings up The Scream by Edvard Munch and the fact that it's actually a depiction of a real atmospheric event. Rebecca talks the use of fractal studies to determine the authenticity of Jackson Pollock art. She also explores the artistic value of scientific artifacts like the controversial plaque attached to Pioneer 10 depicting a naked man and woman, and the interstellar Arecibo Message, sent by Frank Drake in 1974. You'll even hear how Frank worked himself into the message and what that has to do with Albrecht Durer's self-portrait painted in the year 1500. Finally, we turn to what Rebecca's been up to recently. Her new book Mixed Signals came out in January of this year. Keep up with her on her website at and follow her on X @rebecca_charbon and on BlueSky @rebeccacharbon.bsky.social. We hope you enjoy this episode of The LIUniverse, and, if you do, please support us on Patreon. Credits for Images Used in this Episode: A young Milky Way-like galaxy and a background quasar 12 billion and 12.5 billion light-years away, respectively. – Credit: ALMA (ESO/NAOJ/NRAO), M. Neeleman & J. Xavier Prochaska; Keck Observatory Artist's concept of a high red-shift galaxy. – Credit: Alexandra Angelich (NRAO/AUI/NSF) John Young and Gus Grissom are suited for the first Gemini flight March 1965. Norman Rockwell, 1965. – Credit: Smithsonian National Air and Space Museum / Norman Rockwell Edvard Munch, 1893, The Scream. – Credit: Edvard Munch / National Gallery of Norway (Public Domain) Fractal study of Jackson Pollock art. – Credit: “Perceptual and physiological responses to Jackson Pollock's fractals,” R. Taylor, et al, Front. Hum. Neurosci., 21 June 2011. The Arecibo message. – Credit: Creative Commons NASA image of Pioneer 10's famed Pioneer plaque. – Credit: NASA Albrecht Durer self-portrait. – Credit: Albrecht Dürer - Alte Pinakothek (Public Domain)

The legendary ‪Charlie Morley‬ is talking about his IASD presentation in June 2025. In his keynote talk, Charlie will be discussing the remarkable results of two recent scientific studies that used lucid dreaming as a treatment for Post Traumatic Stress Disorder (PTSD). The results of the studies were quite remarkable, with the average PTSD score dropping so far below the medical threshold that dozens of participants were no longer classified as having PTSD by the end of the one-week study. He will also discuss the initial refusal to publish from many journals, the eventual publication in the peer-reviewed journal Traumatology, and his controversial TED talk on the subject that was blacklisted over disputed data. So, join us at this exciting talk to explore how lucid dreaming may well be one of the most promising interventions for trauma currently available.✨ Join Us at the IASD Conference! ✨The International Association for the Study of Dreams (IASD) is hosting its annual conference, bringing together some of the brightest minds in dream research, art, psychology, and spirituality. This is your chance to connect with a global community of dreamers, attend insightful presentations, and expand your understanding of the dream world.

Dans cet épisode, Romain Giop explique en détail les mécanismes en jeu lors des principales douleurs attribuées aux migraines. Il évoque comment traduire la littérature en pratique, quelle place attribuer à la thérapie manuelle, et prodigue quelques conseils utiles aux patients souffrant de migraines, notamment en termes d'activité physique. Extraits sonores Fais pas ci, fais pas ça | Interprété par Jacques Dutronc | Ecrit par Jacques Lanzmann et Anne Segalen | Album : il est cinq heures | 1968 References Watson, D. H. & Drummond, P. D. The Role of the Trigemino Cervical Complex in Chronic Whiplash Associated Headache: A Cross Sectional Study. Headache: J. Head Face Pain 56, 961–975 (2016) Luedtke, K. & May, A. Stratifying migraine patients based on dynamic pain provocation over the upper cervical spine. J. Headache Pain 18, 97 (2017) Burstein, R., Noseda, R. & Borsook, D. Migraine: Multiple Processes, Complex Pathophysiology. J. Neurosci. 35, 6619–6629 (2015) Carvalho, G. F. et al. Physical therapy and migraine: musculoskeletal and balance dysfunctions and their relevance for clinical practice. Braz. J. Phys. Ther. 24, 306–317 (2020) Luedtke, K., Starke, W. & May, A. Musculoskeletal dysfunction in migraine patients. Cephalalgia 38, 865–875 (2017) Soutenez-nous sur Tipeee !

References Front.Cell. Neurosci., 09 March 2015 Guerra,DJ 2024 notes Haggard, M. 1958. "I am a Lonesome Fugitive" Roy Buchanan https://open.spotify.com/track/4LSx92Q1CqfW8ouL0WJZkw?si=c3a128ffca274864 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Avant la saison 7 de Neurosapiens, je vous propose de (re)découvrir des épisodes! Ce mois-ci focus sur l'amour et le plaisir! Découvrez le livre NEUROSAPIENS, sorti le 26 janvier aux éditions Les Arènes ! Pour apprendre à créer rapidement et à moindre coût son podcast, c'est par ici ! Dans le monde entier et de tout temps, les gens aiment. Les mythes et légendes portent sur l'amour et son contraire. Les anthropologues ont découvert que l'amour romantique existait dans plus de 170 sociétés humaines ! L'amour semble être la pierre angulaire de notre espèce mais aussi de bien des espèces animales. Dans cet épisode, nous répondrons aux questions suivantes :  Que se passe-t-il dans le cerveau quand on tombe amoureux ?  L'amour dure-t-il réellement 3 ans ? Et pourquoi tombe-t-on amoureux d'une personne plutôt qu'une autre ? ____________ Si vous souhaitez avoir un éclairage neuro sur un sujet en particulier de la vie quotidienne, de notre fonctionnement, écrivez-moi à neurosapiens.podcast@gmail.com Production, animation, réalisation et illustration : Anaïs Roux Le podcast en version blog : www.neurosapiens.fr A bientôt pour un nouvel épisode ! ____________ SOURCES Bartels A, Zeki S. The neural basis of romantic love. Neuroreport. 2000 Nov 27;11(17):3829-34. doi: 10.1097/00001756-200011270-00046. PMID: 11117499. Acevedo BP, Aron A, Fisher HE, Brown LL. Neural correlates of long-term intense romantic love. Soc Cogn Affect Neurosci. 2012 Feb;7(2):145-59. doi: 10.1093/scan/nsq092. Epub 2011 Jan 5. PMID: 21208991; PMCID: PMC3277362. Insel TR, Winslow JT, Wang Z, Young LJ. Oxytocin, vasopressin, and the neuroendocrine basis of pair bond formation. Adv Exp Med Biol. 1998;449:215-24. doi: 10.1007/978-1-4615-4871-3_28. PMID: 10026808. Cormier, Z. Gene switches make prairie voles fall in love. Nature (2013). S. Stroope et al., Marital characteristics and the sexual relationships of U.S. older adults: an analysis of national social life, health, and aging project data, in Arch. Sex. Behav., vol. 44, pp. 233-247, 2015. B. P. Acevedo et al., Neural correlates of long-term intense romantic love, in Social Cognitive and Affective Neuroscience, vol. 7, pp. 145-159, 2012. K. D. O'Leary et al., Is long-term love more than a rare phenomenon ? If so, what are its correlates ? in Social Psychology and Personality Science, vol. 3, pp. 241-249, 2012. Insel, T. R., and Hulihan, T. (1995). A gender-specific mechanism forpair bonding: Oxytocin and partner preference formation in mo-nogamous voles. Behav. Neurosci. 109, 782–789. Insel, T. R., and Shapiro, L. E. (1992). Oxytocin receptor distributionreflects social organization in monogamous and polygamousvoles. Proc. Natl. Acad. Sci. USA 89, 5981–5985 Helen Fisher, Why We Love : The Nature and Chemistry of Romantic Love, Henry Holt, 2004 Helen Fisher, Why Him? Why Her? : Finding Real Love By Understanding Your Personality Type, Oneworld Publications UK-Commonwealth, 2009.  Musique d'intro KEEP ON GOING Musique proposée par La Musique Libre Joakim Karud - Keep On Going :https://youtu.be/lOfg0jRqaA8 Joakim Karud : https://soundcloud.com/joakimkarud

From Basel, Switzerland to the summer of love in San Francisco. What did we learn about LSD, and why did it fall out of favor in the US? Part 2 will explore what's next in research... Audio Correction: Colby misspoke 4:15: meant to say “Methergine is used for postpartum hemorrhage after delivery,” said “hemorrhage after bleeding” (which of course is redundant and a mistake). Article on Ergotamine association with the Salem Witch Trials (from the Outside Hustle, Colby's other blog): Blotter Art examples: https://keseyblotterart.com/ References: Bryant C, Clark J. “How LSD Works.” Stuff You Should Know [podcast] 5 May 2016. Dyck E. LSD: a new treatment emerging from the past. CMAJ. 2015 Aug 4;187(14):1079–80. doi: 10.1503/cmaj.141358. Epub ahead of print. PMID: 26243813; PMCID: PMC4592308. Dyck, E. (2006). ‘Hitting Highs at Rock Bottom': LSD Treatment for Alcoholism, 1950–1970. Soc. Hist. Med. 19: 313-329. [PDF] Gasser, P. et al. (2014). Safety and Efficacy of Lysergic Acid Diethylamide-Assisted Psychotherapy for Anxiety Associated With Life-threatening Diseases. J. Nerv. Ment. Dis. 202: 513-520. [Full text] Irwin, S. A., et al. (2013). Daily Oral Ketamine for the Treatment of Depression and Anxiety in Patients Receiving Hospice Care: A 28-Day Open-Label Proof-of-Concept Trial. J. Palliat. Med. 16: 958-965. [PDF] Pollen M. “How to Change Your Mind: What the New Science of Psychedelics Teaches us About Consciousness, Dying, Addiction, Depression, and Transcendence.” Penguin Press. New York. 2018. Sandison, R. A., et al. (1954). The therapeutic value of lysergic acid diethylamide in mental illness. J. Ment. Sci. 100: 491-507. [Summary] Sandison, R. A. & Whitelaw, J. D. A. (1957). Further studies of the therapeutic value of lysergic acid diethylamide in mental illness. J. Ment. Sci. 103: 332-343. [Summary] Sessa, B. (2008). Can psychedelic drugs play a role in palliative care? Eur. J. Pall. Care 15: 235-237. [PDF] Simmons, J. Q., et al. (1966). Modification of Autistic Behavior with LSD-25. Am. J. Psych. 122: 1201-1211. [Summary] Smart, R. G. & Storm, T. (1964). The Efficacy of LSD in the Treatment of Alcoholism. Quart. J. Alcohol 25: 333-338. [PDF] Smith, C. M. (1958). A New Adjunct to the Treatment of Alcoholism: The Hallucinogenic Drugs. Quart. J. Alcohol 19: 406-417. [PDF] Shroder T. “Apparently Useless: The Accidental Discovery of LSD. The Atlantic. 9 Sept 2014. Available at: https://www.theatlantic.com/health/archive/2014/09/the-accidental-discovery-of-lsd/379564/ Tanne, J. H. (2004). Humphrey Osmond. BMJ 328: 713. [Full text] Vollenweider F. X. & Kometer, M. (2010). The neurobiology of psychedelic drugs: implications for the treatment of mood disorders. Nature Rev. Neurosci. 11: 642-651. [PDF]

In this captivating episode, we embark on a fascinating journey into the world of meditation and its potential as a treatment and preventive measure for Alzheimer's disease. While meditation is widely recognized for its ability to reduce stress, depression, and anxiety, it turns out there may be even more to this ancient practice.   Join us as we delve deeper into the remarkable imaging studies that prove structural changes in the brains of regular meditators. These changes not only contribute to enhanced cognitive behavior and memory but also serve as a protective mechanism against the onset of dementia.   However, the burning question remains: How significant is this data? By exploring the methodologies employed in these studies and understanding the implications of the results, we aim to shed light on the true potential of meditation in combating Alzheimer's.   Although we acknowledge that we are still in the early stages of research, it becomes clear that meditation is a wonderful intervention worth recommending. Tune in as we explore the captivating intersection of meditation, brain health, and the fight against Alzheimer's disease. Don't miss this enlightening episode of the Wild Health Podcast!   Refernces: Effects of Meditation on Structural Changes of the Brain in Patients With Mild Cognitive Impairment or Alzheimer's Disease Dementia. Front. Hum. Neurosci., 12 November 2021 Sec. Cognitive Neuroscience https://www.frontiersin.org/articles/10.3389/fnhum.2021.728993/full   Effect of an 18-Month Meditation Training on Regional Brain Volume and Perfusion in Older Adults. JAMA Neurol. 2022;79(11):1165-1174. doi:10.1001/jamaneurol.2022.3185 https://jamanetwork.com/journals/jamaneurology/fullarticle/2796818

CONTENT WARNING: child sexual abuse, sexual assault, intimate partner violence Aly Dearborn is back to help break down the similarities between Autism and Borderline Personality Disorder as it relates to confusion among clinicians and the too-often misdiagnosis of Autistic females. This professional take is sprinkled with personal examples of how this gap in knowledge has impacted Candice and Aly throughout their lives. They also give a sneak peek into the content of their upcoming presentation for the 2023 IITAP Symposium! Connect with Aly Information for Domestic Violence and Sexual Assault Counselors Closed Captions References: 1) Cazalis, et al - Evidence that 9 of 10 Autistic Females Victims of Sexual Violence. Front. Behav. Neurosci., 26 April 2022; Sec. Pathological Conditions, Volume 16 - 2022 |  2) Bargiela, S., Steward, R., and Mandy, W. The experiences of late-diagnosed women with autism spectrum conditions: an investigation of the female autism phenotype. J. Autism Dev. Disord. 2016; 46, 3281–3294. doi: 10.1007/s10803-016-2872-8 3) Fusar-Poli, L., Brondino, N., Politi, P. et al. Missed diagnoses and misdiagnoses of adults with autism spectrum disorder. Eur Arch Psychiatry Clin Neurosci 2022.; 272, 187–198 ;https://doi.org/10.1007/s00406-020-01189-w 4) Pecora LA, Hancock GI, Mesibov GB, Stokes MA. Characterising the Sexuality and Sexual Experiences of Autistic Females. J Autism Dev Disord. 2019 5) Pecora LA, Hooley M, Sperry L, Mesibov GB, Stokes MA. Sexuality and Gender Issues in Individuals with Autism Spectrum Disorder. Child Adolesc Psychiatr Clin N Am. 2020 Jul;29(3):543-556. doi: 10.1016/j.chc.2020.02.007. Epub 2020 Apr 3. PMID: 32471601.

Dr. Nally's checks your Egg IQ asking you five questions about eggs. Send your answers and your T-shirt size to questions@docmuscles.com. The first person to correctly answer will win a free DocMuscles.com T-Shirt. Dr. Nally talks about how a pen and notepad can change your memory in just 66 days. You're not going to want to miss this one. Dr. Nally's Favorite Leather Notebook Cover: https://amzn.to/3JQyX7Z Dr. Nally's Favorite Moleskin Journal: https://amzn.to/3YxKf5H Show Note References: Umejima K, Ibaraki T, Yamazaki T, Sakai K. Paper notebooks vs mobile devices: Brain activation differences during memory retrieval. Front. Behav. Neurosci., 19 March 2021(15). https://doi.org/10.3389/fnbeh.2021.634158 Vanderbilt University, Treadway M, Zald D. Dopamine impacts your willingness to work. Journal of Neuroscience 2 May 2012.

We are joined again by Dr. Asher Brandt, Professor of Biochemistry at the Saint Joseph University, Connecticut, specializing in psychedelic pharmacology. We discuss a recently published paper about how Single Nucleotide Polymorphisms, (SNPs, pronounced “snips”) might alter the pharmacological signaling of potentially therapeutic psychedelics.SNPs are the most common type of genetic variation among people. Specifically, it's a genomic variant at a single base position in the DNA, which can lead to a single point amino acid mutation in the subsequently synthesized protein.In the study, the authors examined whether sequence variations in the 5-HT2A receptor gene affect the signaling of some of the most used psychedelic drugs such as LSD, mescalin, psilocybin. They examined the in vitro pharmacology of seven non-synonymous SNPs, which give rise to a variant of 5-HT2A serotonin receptors. What they found is that these non-synonymous SNPs exert statistically significant effects on not just the the efficacy but also the potency of four therapeutically relevant psychedelics.What's mind blowing, in our opinion, is that the in vitro pharmacological effects of the SNP drug actions at 5-HT2A receptor are both amino acid and drug specific.References:Schmitz et al. (2022). 5-HT2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics. ACS Chem. Neurosci. 2022, 13, 16, 2386–2398.NCBI SNPs Database (dbSNP) url: https://www.ncbi.nlm.nih.gov/snp/

As we see more patients who have had Covid-19, we ask psychiatrist, Dr. Imaan Alaidroos, to speak with us about the neuropsychiatric impact of the disease. In this episode, Dr. Alaidroos outlines the treatments that are currently being studied for the neuropsychiatric symptoms of Covid-19. We also chat about the implications of these symptoms for the field of mental health. Hosts: Alan, Toshia Guest: Imaan Alaidroos, MD References: 7. Qureshi, A. I., Baskett, W. I., Huang, W., Shyu, D., Myers, D., Raju, M., Lobanova, I., Suri, M., Naqvi, S. H., French, B. R., Siddiq, F., Gomez, C. R., & Shyu, C. R. (2021). Acute Ischemic Stroke and COVID-19: An Analysis of 27 676 Patients. Stroke, 52(3), 905–912. https://doi.org/10.1161/STROKEAHA.120.031786 8. Helms J, Kremer S, MerdjiH, Clere-JehlR, Schenck M, KummerlenC, et al. Neurologic features in severe SARS-CoV-2 infection. N EnglJ Med. 2020;382:2268–2270. doi: 10.1056/NEJMc2008597. 9. FerrandoSJ, KlepaczL, Lynch S, TavakkoliM, DornbushR, BaharaniR, Smolin Y, Bartell A. COVID-19 psychosis: a potential new neuropsychiatric condition triggered by novel coronavirus infection and the inflammatory response? Psychosomatics. 2020;61:551–555. doi: 10.1016/j.psym.2020.05.012. 10. Parra A, JuanesA, LosadaCP, Álvarez-SesmeroS, Santana VD, Martí I, et al. Psychotic symptoms in COVID-19 patients. A retrospective descriptive study. Psychiatry Res. 2020;291:113254. doi: 10.1016/j.psychres.2020.113254. 11. Farooq, S., Tunmore, J., Wajid Ali, M., & Ayub, M. (2021). Suicide, self-harm and suicidal ideation during COVID-19: A systematic review. Psychiatry research, 306, 114228. https://doi.org/10.1016/j.psychres.2021.114228 12. Stefano, G. B., Büttiker, P., Weissenberger, S., Ptacek, R., Wang, F., Esch, T., Bilfinger, T. V., & Kream, R. M. (2021). Biomedical Perspectives of Acute and Chronic Neurological and Neuropsychiatric Sequelae of COVID-19. Current neuropharmacology, 10.2174/1570159X20666211223130228. Advance online publication. https://doi.org/10.2174/1570159X206662112231 13. de Erausquin, G. A., Snyder, H., Carrillo, M., Hosseini, A. A., Brugha, T. S., Seshadri, S., & CNS SARS-CoV-2 Consortium (2021). The chronic neuropsychiatric sequelae of COVID-19: The need for a prospective study of viral impact on brain functioning. Alzheimer's & dementia : the journal of the Alzheimer's Association, 17(6), 1056–1065. https://doi.org/10.1002/alz.12255 14. PashaeiY. Drug repurposing of selective serotonin reuptake inhibitors: Could these drugs help fight COVID-19 and save lives? J. Clin. Neurosci. 2021;88:163–172. doi: 10.1016/j.jocn.2021.03.010. 15. Dąbrowska, E., Galińska-Skok, B., & Waszkiewicz, N. (2021). Depressive and Neurocognitive Disorders in the Context of the Inflammatory Background of COVID-19. Life (Basel, Switzerland), 11(10), 1056. https://doi.org/10.3390/life11101056 Kępińska AP, Iyegbe CO, Vernon AC, Yolken R, Murray RM, Pollak TA. Schizophrenia and Influenza at the Centenary of the 1918-1919 Spanish Influenza Pandemic: Mechanisms of Psychosis Risk. Front Psychiatry. 2020 Feb 26;11:72. doi: 10.3389/fpsyt.2020.00072. PMID: 32174851; PMCID: PMC7054463.

Fast Takes - Episode 42 In this episode, Brian Sandroff, PhD, senior research scientist in the Center for Neuropsychology and Neuroscience Research at Kessler Foundation, talks about his peer-reviewed article, “Developing the Rationale for Including Virtual Reality in Cognitive Rehabilitation and Exercise Training Approaches for Managing Cognitive Dysfunction in MS,” published in April 2022, in the journal NeuroSci. He discusses how virtual reality could increase sensory input and promote multisensory integration and processing during rehabilitation for multiple sclerosis. Learn more about: 
Dr. Brian Sandroff, https://kesslerfoundation.org/about-us/foundation-staff/brian-m-sandroff-phd Center for Neuropsychology and Neuroscience Research, https://kesslerfoundation.org/center-neuropsychology-and-neuroscience-research The peer-reviewed article at www.mdpi.com/2673-4087/3/2/15 Co-authors: Carly L. A. Wender, https://kesslerfoundation.org/about-us/foundation-staff/carly-wender, John DeLuca, https://kesslerfoundation.org/aboutus/John%20DeLuca, Brian M. Sandroff ======================================================= Tuned in to our podcast series lately? Join our listeners in 90 countries who enjoy learning about the work of Kessler Foundation. Be sure to subscribe to our SoundCloud channel “KesslerFoundation” for more research updates. 
Follow us on Facebook, Twitter, and Instagram. Listen to us on Apple Podcasts, Spotify, SoundCloud, or wherever you get your podcasts. This podcast was recorded remotely on May 4, 2022, and was edited and produced by Joan Banks-Smith, Creative Producer for Kessler Foundation.

References Dr. Guerra's notes Cancer Res. 2011 May 1; 71(9): 3400–3409 Front. Neurosci., 17 May 2017 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

Suurimmalle osalle on tuttua äitiaivot-ilmiö, jolla viitataan aikaan lapsen saamisen jälkeen, kun äiti saattaa kärsiä mm. aivosumusta, muistamattomuudesta ja tarkkaamattomuudesta. Kyseessä ei suinkaan ole urbaanilegenda tai kätevä tekosyy univelkaiselle äidille, vaan ihan tutkitut muutokset synnyttäneen aivoissa. Äitiys siis muuttaa monia asioita äidin elämässä, jopa hänen aivonsa! Mutta onko äitiaivot pelkästään huono asia vai seuraako siitä jotain hyvääkin? Mitä ilmiön taustalla on, mikä sen syvempi tarkoitus äidille on? Säde jakaa meille uusimpia tutkimustuloksia. Jaksossa pohdimme myös muutosta laajemmin. Onko tässä ajassa jotenkin ihanteellista, että äitiys muuttaisi naisen elämää mahdollisimman vähän? Mitä hyötyä äitiydestä ja äitiyslomasta on työelämän kannalta? Muun muassa näitäkin aiheita pääsimme sivupoluilla pohtimaan. Olet lämpimästi tervetullut seuraamme oppimaan uutta, saamaan vertaistukea ja viihtymään! Lähteet: Pilyoung Et al.,2016. The maternal brain and its plasticity in humans. Hormones and Behavior. Martínez-García et al., 2021. Do pregnancy-induced brain changes reverse? The brain of a mother six years after parturition. Brain Sci. Pawluski et al., 2022. Less can be more: Fine tuning the maternal brain. Neurosci. Biobehav. Rev. Gupta, P.D., 2021. Neuropsychology of Expectant Mothers. J. Clin. Surg. Carolyn Keating, 2018: Baby on the Brain

我們以圍棋這項頂尖智力競技，作為人類認知功能隨年齡消長的模型分析，「一代不如一代」是錯誤的推論，這項研究成果剛獲《精神醫學與臨床神經科學》（Psychiatry and Clinical Neurosciences, IF=5.118）期刊接受。 圍棋是最困難的智力競技，規則長達百年而不變，而且有明確的勝負，很適合詮釋為人類認知功能在專業領域的表現，也可以公平地比較每個世代認知功能與專業表現的年齡軌跡。 我們分析從1980年以來的職業圍棋對局資料庫，其中62位曾獲世界冠軍棋士以及與他們曾經對局過的2,269位職業棋士，共94,189盤對局勝負的分析，觀察每個世代的圍棋世界冠軍在職涯歷程中棋力隨年齡的改變。 我們發現所有世代的職業棋士，代表認知功能的「全歷史等級分」隨著年齡大致呈倒U型的軌跡。每個世代中，較年輕的世代達到最巔峰的棋力，都超過上一個世代；而且達到巔峰棋力的年齡也比上一個世代更年輕。例如最年輕的Z世代棋士達到巔峰棋力的年齡約在20歲左右，而先前的X世代或Y世代棋士則是大約在25-30歲時方達到巔峰棋力，而最資深的戰後嬰兒潮世代則大約是在30歲之後才達到巔峰棋力。最年輕的Z世代棋士達到巔峰棋力的全歷史等級分超過3500，而Y世代的巔峰棋力則在3500左右，最資深的Ｘ世代與戰後嬰兒潮的巔峰棋力則低於3400。總結來說，在圍棋領域菁英的認知功能，是一代超越上一代，而且越年輕的世代達到認知功能巔峰的時間也比上一個世代更早、更年輕。 另一項高難度的智力競技，西洋棋世界冠軍的棋力年齡軌跡，與本研究中圍棋世界冠軍的結論也非常相似，由這兩個重要的人類認知功能模型可以推論「一代不如一代」是沒有任何實證根據的說法。

Recipient of the 2012 Global HR Excellence Award in Leadership, the 2016 Global Coaching Leadership Award, and voted 2020 Executive Coach of the Year in Singapore, Marcel Daane is an accredited Professional Certified Coach with the International Coaching Federation.Since 2010, Marcel has been partnering with organizations, teams, and individuals in Asia and North America providing leadership assessments, feedback, and coaching to align the leadership skills of senior managers and behaviors of teams with the organization's brand promise and culture.As a coach and author, Marcel is considered one of the world's authorities in mind-body leadership, a whole person approach to leadership using a combination of energy practices, mindfulness, and somatic awareness. that enables leaders to choose the right energy projection for lasting results in how they perform, live, and lead. He is the author of his critically acclaimed leadership and performance books “Headstrong Performance,” and “Five Energies of Horrible Bosses and How Not To Become One.”Marcel is a life-long practitioner of Martial Arts and is the son of a celebrated Political Activist who taught him early on that life has greater meaning when we are of service to others rather than merely to ourselves. In his spare time, Marcel volunteers as a Mental Health & Wellness advocate and he loves to spend quality family time with his wife, Ursula, and Daughter, Kilani.Marcel holds a post-graduate degree in the Neurosci­ence of Leadership from Middlesex University an Undergraduate Degree in Complementary Medicine from Charles Sturt University coupled with multiple certifications in Executive Coaching and Sports Performance CoachingMichael and Marcel discuss the five energies, pillars of wisdom and how simple this all really is and how to use it to be a better leader.  Awareness is key here and Marcel breaks it down so elegantly.#MarcelDaane #fiveenergiesofhorribleboxxes

HIFT representa un método apropiado para mejorar el rendimiento cognitivo, específicamente la memoria de trabajo. Autor Jan Wilke Department of Sports Medicine, Goethe University Frankfurt am Main, Ginnheimer Landstraße 39, 60487, Frankfurt am Main, Germany. wilke@sport.uni-frankfurt.de. Enlace al Articulo Original en Ingles Los ejercicios aeróbicos y de resistencia (con pesas) aumentan de manera inmediata el rendimiento cognitivo (PC). El entrenamiento funcional de alta intensidad (HIFT) combina las características de ambos regímenes, pero su efecto sobre el rendimiento cognitivo no está claro. Treinta y cinco individuos sanos (26,7 ± 3,6 años, 18 mujeres) fueron asignados al azar a tres grupos. El primer grupo (HIFT) realizó un entrenamiento funcional con el máximo esfuerzo y en formato de circuito involucrando todos los grupos musculares del cuerpo, mientras que el segundo grupo (WALK) caminó al 60% de la reserva de frecuencia cardíaca. El tercer grupo permaneció físicamente inactivo leyendo un libro (CON). Antes y después del período de intervención que duro 15 minutos, el rendimiento cognitivo se evaluó con el Stroop Task, Trail Making Test y Digit Span Test. Se utilizaron ANOVA de medidas repetidas e intervalos de confianza del 95% post-hoc para detectar diferencias en los grupos y tiempo (previo y posterior a los protocolos). Se encontró una interacción significativa entre los grupos y el tiempo para la condición de conteo hacia atras de Digit Span Test (p = 0.04, IC 95%). HIFT fue superior a WALK y CON. Ademas, el análisis de la puntuación total del Digit Span Test y la condición incongruente del Stroop Task, reveló efectos pre y post (p 0.05). En conclusión, HIFT representa un método apropiado para mejorar de manera inmediata la memoria de trabajo, siendo potencialmente superior al ejercicio de tipo aeróbico moderado. El entrenamiento funcional de alta intensidad (HIFT, por sus siglas en inglés) como metodo de entrenamiento es una tendencia muy popular en el mundo del fitness, que integra el esfuerzo cardiovascular y muscular. El HIFT utiliza movimientos funcionales, multimodales y multiarticulares, por ejemplo, sentadillas, flexiones y burpees (Buckley et al., 2015). Los ejercicios funcionales utilizan todo el cuerpo y provocan un patrón de reclutamiento motor universal (Heinrich et al., 2014). El HIFT también tiene una configuración de intervalos de descanso mínimo o casi nulo (Feito, Heinrich, Butcher, & Poston, 2018). Las características mencionadas anteriormente confieren al HIFT la capacidad de mejorar la fuerza y la potencia muscular, así como de generar adaptaciones cardiovasculares anaeróbicas y aeróbicas, por lo que se ha demostrado que el HIFT desencadena efectos beneficiosos sobre el consumo de oxígeno (Vo2max), la potencia anaeróbica y fuerza muscular (Alcaraz et al., 2008; Brisebois et al., 2018; Menz et al., 2019). Además, el HIFT parece causar también beneficios neurofisiologicos. Los primeros estudios neurocientíficos asocian el HIFT con una reducción aguda del BDNF (García-Suárez et al., 2020), y curiosamente, en intervenciones más largas con un incremento del BDNF basal (Murawska-Ciałowicz et al., 2021). Además, una sesión aguda de entrenamiento del circuito HIFT mejoró la memoria a corto plazo y el control inhibitorio (Wilke et al., 2020) y una intervención de tres meses mejoró el rendimiento en el aprendizaje espacial, la separación de patrones y la capacidad de atención (Ben-Zeev, Hirsh, Weiss, Gornstein y Okun, 2020). En este estudio la intervencion consistía en una sesion de 15 ejercicios funcionales para todo el cuerpo, realizados en formato de circuito con repeticiones de 20 segundos de entrenamiento y 10 segundos de descanso. Con una duración total de 15 minutos. La selección de los ejercicios se basó en dos objetivos principales (a) la implicación de los principales grupos musculares para aumentar el consumo absoluto de oxígeno y (b) la simulación de patrones de movimiento fundamentales de uso diario (por ejemplo, sentadillas, desplantes, flexiones). El rendimiento cognitivo (CP), que puede subdividirse en funciones cognitivas de orden superior (por ejemplo, control inhibitorio o memoria de trabajo) y de orden inferior (por ejemplo, atención o tiempo de reacción). Las revisiones sistemáticas disponibles han investigado los efectos del ejercicio de tipo aeróbico, han detectando un efecto positivo en el CP incluso cuando se realiza como un único entrenamiento. Tanto el ejercicio continuo aerobico de intensidad moderada como de alta intensidad han reportado un impacto positivo en el rendimiento cognitivo. El test de Stroop consta de tres partes. En la primera y segunda sección de captación de la atención, se pide a los participantes que nombren lo más rápidamente posible las palabras escritas o los colores que aparecen en una hoja. La tercera sección representa una medida de control de la inhibición. Las palabras de colores se presentan de forma incongruente (por ejemplo, "verde" escrito en rojo o "azul escrito en amarillo"). Aquí, los participantes deben nombrar el color de la palabra mientras ignoraban las letras. Para el análisis posterior, se registra el tiempo necesario para completar la tarea. Se ha demostrado que el test de Stroop presenta una alta fiabilidad (ICC: 0,82) y consistencia interna (alfa de Cronbach: 0,93-0,97). Es el Episodio 4 Correr y Salud Mental puedes aprender mas sobre esta prueba cognitiva. El test de creación de rastros (TMT) consta de dos partes. En la parte A, los participantes deben conectar números linealmente crecientes utilizando un bolígrafo a la máxima velocidad posible. En la parte B, deben enlazar números y letras sucesivos (por ejemplo, del 1 al a y del 2 al b) de forma alterna. Al igual que en la prueba Stroop, se registra el tiempo necesario para completar la prueba. Los resultados de la prueba proporcionan una medida de detección visual/atención (TMT-A) y de flexibilidad cognitiva/memoria de trabajo (TMT-B). Se ha demostrado una alta fiabilidad (ICC: 0,81-0,86) y validez de constructo de la TMT. En la prueba de amplitud de dígitos, se realizan dos condiciones. En la primera, los participantes tienen que memorizar y repetir cantidades crecientes de números que se les leen. Al principio, deben recordar cuatro números. Si la memorización es satisfactoria, se les leen cinco números los memorizan y repiten, y asi continua subiendo la cantidad de numeros leidos que tienen que memorizar y repetir. Para cada paso, se realizan dos repeticiones y se otorgan uno o cero puntos en función del éxito de la memorización. La prueba termina si se fallan los dos ensayos. La segunda condición es idéntica a la primera, pero los números deben repetirse en orden inverso (por ejemplo, 2, 4, 7, 9 se convierte en 9, 7, 4, 2). Ambas partes de la prueba y la puntuación compuesta están relacionadas con la memoria a corto plazo y la memoria de trabajo. La prueba de amplitud de dígitos es fiable en las mediciones repetidas (r = 0,73). Los participantes del grupo WALK realizaron 15 minutos de marcha en cinta rodante al 60% de la reserva de frecuencia cardíaca individual. La RFC se determina mediante la fórmula de Karvonen (frecuencia cardíaca en reposo + ((frecuencia cardíaca máxima - frecuencia cardíaca en reposo) x intensidad). Esto es porque Los resultados de este estudio sugieren que el HIFT puede mejorar de forma inmediata el rendimiento cognitivo, concretamente la memoria a corto plazo/de trabajo y el control inhibitorio. Siendo el HIFT ligeramente superior al ejercicio aerobico continuo. Los autores mencionan que los posibles mecanismos que explican este aumento en el rendimiento cognitivo son Aumento de la perfusión cerebral tras el ejercicio de resistencia (Querido & Sheel, 2007; Ogoh & Ainslie, 2009). El aumento de los niveles séricos de cortisol y BDNF, que se ha reportado con entrenamiento de resistencia (pesas) (Tsai, et al. 2014; Yarrow, et al. 2010). Sin embargo los resultados son contradictorios en el sentido que no reportan mejoras con el ejercicio aeróbico, las cuales han sido encontradas en estudios anteriores con intensidades del 40 al 80% de la capacidad maxima de oxigeno ( Brisswalter, et al. 2002; Chang, et al. 2012). Acerca de este tema, Browne et al. 2017 sugiere que multiples factores, como el nivel de forma física y el modo de ejercicio, influyen en la relación entre el ejercicio y la cognición. Una implicación clinica práctica importante del presente estudio es que el HIFT representa una alternativa al uso de otros métodos de entrenamiento convencionales, no sólo en lo que respecta a la mejora o recuperacion de la función muscular y cardiovascular (Wilke, et al. 2020; Menz, et al. 2019), sino también cuando se pretende mejorar el rendimiento cognitivo a corto plazo. El HIFT también podría ser interesante para los individuos sedentarios con poca motivacion y tiempo limitado para hacer ejercicio, ya que se ha reportado una mayor motivacion intrinseca y mayor disfrute del ejercicio que una actividad de tipo aeróbico moderado (Wilke, et al. 2020). No se investigo la sosteníbilidad de la mejora de la PC, con evaluaciones de seguimiento adicionales, por lo que investigar los cambios 5, 10 15, 30, 60 minutos después o incluso 2, 6, 12, 24 horas después del entrenamiento a largo plazo es una tarea pendiente.No incluyó una comparación con una sesión de entrenamiento aeróbico o de resistencia con pesas de intensidad equivalente, es decir de alta intensidad. Solamente HIFT fue de alta intensidad, pero el ejercicio aeróbico estuvo en el limite superior de ejercicio de baja intensidad, con lo que la diferencia en intensidad pudo haber afectado la comparación. Alcaraz, P. E., Sánchez-Lorente, J., & Blazevich, A. J. (2008). Physical performance and cardiovascular responses to an acute bout of heavy resistance circuit training versus traditional strength training. In Journal of Strength and Conditioning Research (Vol. 22, pp. 667-671): J Strength Cond Res.Ben-Zeev, T., Hirsh, T., Weiss, I., Gornstein, M., & Okun, E. (2020). The Effects of High-intensity Functional Training (HIFT) on Spatial Learning, Visual Pattern Separation and Attention Span in Adolescents. In Frontiers in Behavioral Neuroscience (Vol. 14, pp. 577390): Frontiers Media S.A.Brisswalter, J., Collardeau, M. & René, A. Effects of acute physical exercise characteristics on cognitive performance. Sports Med. 32, 555–566 (2002).Browne, S. E. et al. Effects of acute high-intensity exercise on cognitive performance in trained individuals: a systematic review. Progr. Brain. Res. 234, 161–187 (2017).Buckley, S., Knapp, K., Lackie, A., Lewry, C., Horvey, K., Benko, C., . . . Butcher, S. (2015). Multimodal high-intensity interval training increases muscle function and metabolic performance in females. In Applied Physiology, Nutrition and Metabolism (Vol. 40, pp. 1157-1162): Appl Physiol Nutr MetabChang, Y. et al. The effects of acute exercise on cognitive performance: a meta-analysis. Brain. Res. 1453, 87–101 (2012).Feito, Y., Heinrich, K. M., Butcher, S. J., & Poston, W. S. C. (2018). High-Intensity Functional Training (HIFT): Definition and Research Implications for Improved Fitness. In Sports (Basel, Switzerland) (Vol. 6, pp. 76): MDPI AGGarcía-Suárez, P. C., Rentería, I., Moncada-Jiménez, J., Fry, A. C., & Jiménez-Maldonado, A. (2020). Acute Systemic Response Of BDNF, Lactate and Cortisol to Strenuous Exercise Modalities in Healthy Untrained Women. In Dose-response : a publication of International Hormesis Society (Vol. 18, pp. 1559325820970818): SAGE Publications Inc.Heinrich, K. M., Patel, P. M., O'Neal, J. L., & Heinrich, B. S. (2014). High-intensity compared to moderate-intensity training for exercise initiation, enjoyment, adherence, and intentions: an intervention study. BMC Public Health, 14, 789. doi:10.1186/1471-2458-14-789Menz, V. et al. Functional vs running low-volume high-intensity interval training: effects on VO2max and muscular endurance. J. Sports Sci. Med. 18, 497–504 (2019).Murawska-Ciałowicz, E., de Assis, G. G., Clemente, F. M., Feito, Y., Stastny, P., Zuwała-Jagiełło, J., . . . Wolański, P. (2021). Effect of four different forms of high intensity training on BDNF response to Wingate and Graded Exercise Test. In Scientific Reports (Vol. 11, pp. 8599): Nature Research.Ogoh, S. & Ainslie, P. N. Cerebral blood flow during exercise: mechanisms of regulation. J. Appl. Physiol. 107, 1370–1380 (2009).Querido, J. S. & Sheel, A. W. Regulation of cerebral blood flow during exercise. Sports Med. 37, 765–782 (2007).Tsai, C. et al. Executive function and endocrinological responses to acute resistance exercise. Front Behav Neurosci. 8, 283 (2014).Wilke, J. et al. Effects of high-intensity functional circuit training on motor function and sport motivation in healthy, inactive adults. Scand. J. Med. Sci. Sports 29, 144–153 (2019).Wilke, J., Stricker, V., & Usedly, S. (2020). Free-Weight Resistance Exercise Is More Effective in Enhancing Inhibitory Control than Machine-Based Training: A Randomized, Controlled Trial. In Brain sciences (Vol. 10, pp. 1-10): MDPI AG.Yarrow, J. F., White, L. J., McCoy, S. C. & Borst, S. E. Training augments resistance exercise induced elevation of circulating brain derived neurotrophic factor (BDNF). Neurosci. Lett. 26, 161–165 (2010).

References Biol Psychiatry. 2020 Jan 1; 87(1): 64–73 Front. Neurosci., 26 November 2019 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

On se retrouve cette semaine pour un sujet très très très complexe. Ce sujet m'a vraiment donné du fil à retordre, autant qu'il en donne à tous les chercheurs en neurosciences qui travaillent sur le sujet. Je parle de, roulement de tambour bien que ce soit marqué dans le nom de l'épisode, la conscience !La question : existe-t-il une origine cérébrale de la conscience est une des plus grandes questions du 21ème siècle pour la recherche scientifique. Et avant même que les scientifiques ne s'en mêlent, la conscience, sa définition et son origine a été une grande préoccupation des philosophes.Dans cet épisode, j'essayerais donc de vous partager où nous en sommes aujourd'hui dans la recherche portant sur la conscience. Comment définit-on la conscience ? D'où émerge la conscience ? Peut-on localiser la conscience dans le cerveau ? Quels éléments sont nécessaires pour faire émerger la conscience d'un individu ? Si vous souhaitez avoir un éclairage neuro sur un sujet en particulier de la vie quotidienne, de notre fonctionnement, écrivez-moi à neurosapiens.podcast@gmail.com Production, animation, réalisation et illustration : Anaïs RouxLe podcast en version blog : www.neurosapiens.frA bientôt pour un nouvel épisode !SOURCES :S. Dehaene, Le Code de la conscience, Odile Jacob, 2014. L. Naccache, Le Nouvel Inconscient, Odile Jacob, 2006.S. Dehaene et al., What is consciousness, and could machines have it ?, Science, 27 octobre 2017.M. Babo-Rebelo et al., Neural responses to heartbeats in spontaneous thoughts, Journal of Neuroscience, 27/07/2016.S. Achard et al., Hubs of brain functional networks are radically reorganized in comatose patients, PNAS, en ligne le 26 novembre.S. Silva et al., Disruption of posteromedial large-scale neural communication predicts recovery from coma, Neurology, en ligne le 11/10/2015.O. Gosseries et S. Laureys, La conscience, comment la déceler ?, Pour la Science n°422, décembre 2012.S. Dehaene, J.-P. Changeux, Experimental and theoretical approaches to conscious processing, in Neuron, vol. 70, p. 200, 2011.S. Kouider et al., How rich is consciousness ? The partial awareness hypothesis, in Trends in Cognitive Sciences, vol. 14, pp. 301-307, 2010.Z. Huang et al., Temporal circuit of macroscale dynamic brain activity supports human consciousness, Science Advances, vol. 6, n° 11, eaaz0087, 11 mars 2020.K. Stiefel et al., The claustrum's proposed role in consciousness is supported by the effect and target localization of Salvia divinorum, in Front. Integr. Neurosci., vol. 8, 2014. Voir Acast.com/privacy pour les informations sur la vie privée et l'opt-out. Become a member at https://plus.acast.com/s/neurosapiens.

你覺得全世界、台灣大約有多少人符合「網路成癮」或「網路遊戲成癮」呢？   這集podcast將舉台灣最大型對8110位青少年網路遊戲成癮調查，以及系統性回顧從1996年「網路成癮」這個詞被提出之後，全世界31個國家在這二十多年來共69萬人的最新統合分析結論。   我們也會從實證研究討論「為什麼玩遊戲的時間，不是判斷網路成癮的指標？」、「東西方國家的網路成癮盛行率有差異嗎？」、「隨著網路的普及，近二十年來的網路成癮有越來越多嗎？」   關於網路成癮的基本介紹： https://reurl.cc/aN4Wa4  

The prisoners in Plato's Cave live in a world of projections. They think they see a cat, but it is actually a shadow of a statue of a cat. Is it the same for us? Do we live in a kind of illusion? And if so, what are ways to see through this illusion and lift the fog at least a little? We explore these questions with neuroscientist, Buddhist and ballet dancer Marieke van Vugt.    About Marieke:  Marieke is an assistant professor in the cognitive modeling group at the University of Groningen (The Netherlands). She obtained her PhD with Michael Kahana in the neuroscience program of the University of Pennsylvania, after having spent one year at Brandeis University. After that I did a postdoc with Jonathan Cohen at Princeton University. The main question that guides her research is: how do we think? In what ways do we mind-wander? What effects does that have on decisions? And how can we make our thinking more adaptive by means of contemplative practices such as mindfulness and meditation. She likes to use mathematical models and techniques to better understand those very complicated data. This model-based neuroscience approach allows us to think about the mechanism by which someone thinks, and make more detailed predictions than verbal models.   Resources Marieke's website, twitter and ballet-related pictures on her instagram.  Mind and Life Institute: https://www.mindandlife-europe.org  Evan Thompson: research on whether meditation makes you a better scientist https://evanthompson.me/ Jostein Gaarder (1991). Sophie's World: https://en.wikipedia.org/wiki/Sophie%27s_World Tamboukou M. Archival research: unravelling space/time/matter entanglements and fragments. Qualitative Research. 2014;14(5):617-633. doi:10.1177/1468794113490719 Jostein Gaarder, 1991. Sophie's World Film about neurobiologist Francisco Varela: Monte Grande: What is Life? https://www.imdb.com/title/tt0466070/ Balerinas by Night :http://ballerinasbynight.blogspot.com/ Navillera (Netflix series, 2021) Marieke van Vugt MK (2014) Ballet as a movement-based contemplative practice? Implications for neuroscientific studies. Front. Hum. Neurosci. 8:513. doi: 10.3389/fnhum.2014.00513 Dominic Pettman (2016) Infinite Distraction. Polity Books https://dominicpettman.com/books/infinite-distraction/ Ricard, Matthieu (1999). The Monk and the Philosopher. New York City: Schocken. https://www.amazon.com/Monk-Philosopher-Father-Discuss-Meaning/dp/0805211039  The Brain Facts Book (free download in many languages) https://www.brainfacts.org/the-brain-facts-book Social Psychology experiment on change blindness: https://www.youtube.com/watch?v=vBPG_OBgTWg and https://youtu.be/VkrrVozZR2c?t=101   I hope you enjoy the episode! Mario http://lifefromplatoscave.com/    Here's how to contact me if you have any questions or comments: Twitter: https://twitter.com/lifeplatoscave  Insta: https://www.instagram.com/lifefromplatoscave/ Facebook: https://www.facebook.com/lifefromplatoscave  Illustration © by Julien Penning, Light One Art: https://www.instagram.com/light_one_art/ 

Episode 29: In this episode, host Angie Gust talks about how we can calm our amygdalas. The amygdala is the part of our brain responsible for the experience of stress and can override the thinking part of our brains. If you'd like to try to calm your amygdala, you can try mindfulness meditation, breathing techniques, chanting, and listening to solfeggio frequencies. With regard to the environment, a new organization was recently formed called the Global Alliance for a Green New Deal and  includes lawmakers from every continent except Antarctica.  The goal of the group is to put the principles of a Green New Deal at the center of a global recovery from Covid-19. The group aims to put pressure on world governments ahead of the United Nations climate talks, COP 26, set to take place in Glasgow, Scotland, this November. References Akimoto, K., Ailing Hu, Takuji Yamaguchi, Hiroyuki Kobayashi. Effect of 528 Hz Music on the Endocrine System and Autonomic Nervous System 2018. Health, 2018, 10, 1159-1170 Aronoff, K. Jul 19, 2021.A New Global Group of 21 Lawmakers Will Pressure Countries on Climate Change. New Republic. https://newrepublic.com/article/162999/ilhan-omar-global-green-new-deal Doll A, Hölzel BK, Mulej Bratec S, Boucard CC, Xie X, Wohlschläger AM, Sorg C. Mindful attention to breath regulates emotions via increased amygdala-prefrontal cortex connectivity. Neuroimage. 2016 Jul 1;134:305-313. doi: 10.1016/j.neuroimage.2016.03.041. Epub 2016 Mar 24. PMID: 27033686 Gao, J. et al. Emotional Schema to Counterbalance Fear: A Multi-Modal Functional and Structural MRI Study. Front. Behav. Neurosci., 24 November 2020. https://doi.org/10.3389/fnbeh.2020.548856  Gotink RA, Meijboom R, Vernooij MW, Smits M, Hunink MG. 8-week Mindfulness Based Stress Reduction induces brain changes similar to traditional long-term meditation practice - A systematic review. Brain Cogn. 2016 Oct;108:32-41. doi: 10.1016/j.bandc.2016.07.001.  Jerath, R et al. 2015.Self-Regulation of Breathing as a Primary Treatment for Anxiety. Applied Psychophysiology and Biofeedback 40(2) Kalyani BG, Venkatasubramanian G, Arasappa R, et al. Neurohemodynamic correlates of 'OM' chanting: A pilot functional magnetic resonance imaging study. Int J Yoga. 2011;4(1):3-6. doi:10.4103/0973-6131.7817     McGaugh JL The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annu Rev Neurosci. 2004;27:1-28. Neuron. 2005 Oct 20;48(2):175-87. Contributions of the amygdala to emotion processing: from animal models to human behavior. Phelps EA(1), LeDoux JE. Relax Melodies.The Science Behind Solfeggio Frequencies. https://www.relaxmelodies.com/blog/science-behind-solfeggio-frequencies/ Reynolds-Tylus, T.Psychological Reactance and Persuasive Health Communication: A Review of the Literature. Front. Commun., 31 October 2019. Toplin. RB. Dec 20,2020. The Psychology of Election Denial. Columbian College of Arts &Sciences. https://historynewsnetwork.org/article/178552

Dans le monde entier et de tout temps, les gens aiment. Les mythes et légendes portent sur l'amour et son contraire. Les anthropologues ont découvert que l'amour romantique existait dans plus de 170 sociétés humaines ! L'amour semble être la pierre angulaire de notre espèce mais aussi de bien des espèces animales. Dans cet épisode, nous répondrons aux questions suivantes : Que se passe-t-il dans le cerveau quand on tombe amoureux ? L'amour dure-t-il réellement 3 ans ?Et pourquoi tombe-t-on amoureux d'une personne plutôt qu'une autre ?Si vous souhaitez avoir un éclairage neuro sur un sujet en particulier de la vie quotidienne, de notre fonctionnement, écrivez-moi à neurosapiens.podcast@gmail.com Production, animation, réalisation et illustration : Anaïs Roux  SOURCESBartels A, Zeki S. The neural basis of romantic love. Neuroreport. 2000 Nov 27;11(17):3829-34. doi: 10.1097/00001756-200011270-00046. PMID: 11117499.Acevedo BP, Aron A, Fisher HE, Brown LL. Neural correlates of long-term intense romantic love. Soc Cogn Affect Neurosci. 2012 Feb;7(2):145-59. doi: 10.1093/scan/nsq092. Epub 2011 Jan 5. PMID: 21208991; PMCID: PMC3277362.Insel TR, Winslow JT, Wang Z, Young LJ. Oxytocin, vasopressin, and the neuroendocrine basis of pair bond formation. Adv Exp Med Biol. 1998;449:215-24. doi: 10.1007/978-1-4615-4871-3_28. PMID: 10026808.Cormier, Z. Gene switches make prairie voles fall in love. Nature (2013).S. Stroope et al., Marital characteristics and the sexual relationships of U.S. older adults: an analysis of national social life, health, and aging project data, in Arch. Sex. Behav., vol. 44, pp. 233-247, 2015.B. P. Acevedo et al., Neural correlates of long-term intense romantic love, in Social Cognitive and Affective Neuroscience, vol. 7, pp. 145-159, 2012.K. D. O'Leary et al., Is long-term love more than a rare phenomenon ? If so, what are its correlates ? in Social Psychology and Personality Science, vol. 3, pp. 241-249, 2012.Insel, T. R., and Hulihan, T. (1995). A gender-specific mechanism forpair bonding: Oxytocin and partner preference formation in mo-nogamous voles. Behav. Neurosci. 109, 782–789.Insel, T. R., and Shapiro, L. E. (1992). Oxytocin receptor distributionreflects social organization in monogamous and polygamousvoles. Proc. Natl. Acad. Sci. USA 89, 5981–5985Helen Fisher, Why We Love : The Nature and Chemistry of Romantic Love, Henry Holt, 2004Helen Fisher, Why Him? Why Her? : Finding Real Love By Understanding Your Personality Type, Oneworld Publications UK-Commonwealth, 2009.  Musique d'intro KEEP ON GOINGMusique proposée par La Musique LibreJoakim Karud - Keep On Going : https://youtu.be/lOfg0jRqaA8Joakim Karud : https://soundcloud.com/joakimkarud Voir Acast.com/privacy pour les informations sur la vie privée et l'opt-out. Become a member at https://plus.acast.com/s/neurosapiens.

W dzisiejszym odcinku skupiam się na składnikach mineralnych, których niedobór może albo sprzyjać rozwojowi depresji, albo pogarszać przebieg leczenia. Jednakże, nie namawiam, by od razu rzucić wszystko i biec do apteki (i niekoniecznie w Bieszczady!) po suplementy, bo jak się okazuje więcej nie zawsze znaczy lepiej. Poza tym, to jedzenie jest pierwszym wyborem jeżeli chodzi o dostarczenie składników mineralnych do organizmu, suplementacja później. Omawiam także kwasy omega-3, których wpływ na mózg jest niepodważalny, co ma znaczenie również w kontekście depresji. Jeżeli masz pytania do tego odcinka napisz do mnie na malgorzata@pielichowska.pl Odwiedź moją stronę: https://pielichowska.pl Zostań moim patronem: https://patronite.pl/pielichowska Odwiedź mojego Facebooka: https://www.facebook.com/pielichowska.dietetyk Odwiedź mojego Instagrama: https://www.instagram.com/diet.and.mindfulness/ Literatura:Aly J and Engmann O (2020) The Way to a Human's Brain Goes Through Their Stomach: Dietary Factors in Major Depressive Disorder. Front. Neurosci. 14:582853.Appleton KM, Sallis HM, Perry R, Ness AR, Churchill R. Omega-3 fatty acids for depression in adults. Cochrane Database Syst Rev. 2015 Nov 5;2015(11):CD004692.Liao Y, Xie B, Zhang H, He Q, Guo L, Subramaniapillai M, Fan B, Lu C, Mclntyer RS. Efficacy of omega-3 PUFAs in depression: A meta-analysis. Transl Psychiatry. 2019 Aug 5;9(1):190.Wang, J., Um, P., Dickerman, B. A., & Liu, J. (2018). Zinc, Magnesium, Selenium and Depression: A Review of the Evidence, Potential Mechanisms and Implications. Nutrients, 10(5), 584.

W dzisiejszym odcinku dalej kontynuuję temat związku między dietą a zaburzeniami nastroju, w tym depresyjnymi. Tym razem omawiam witaminy, które mają znaczenie w rozwoju depresji i przebiegu leczenia: witaminy z grupy B, witaminę D i C. Dlaczego są ważne, jakie są źródła, czy potrzebna jest suplementacja? Zapraszam do słuchania. Jeżeli masz pytania do tego odcinka napisz do mnie na malgorzata@pielichowska.pl Odwiedź moją stronę: https://pielichowska.pl Zostań moim patronem: https://patronite.pl/pielichowska Odwiedź mojego Facebooka: https://www.facebook.com/pielichowska.dietetyk Odwiedź mojego Instagrama: https://www.instagram.com/diet.and.mindfulness/ Literatura: Aly J and Engmann O (2020) The Way to a Human's Brain Goes Through Their Stomach: Dietary Factors in Major Depressive Disorder. Front. Neurosci. 14:582853.Patrick R., Ames B., Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior. The FASEB Journal Vol.29, No.6 , pp:2207-2222.Anglin RE, Samaan Z, Walter SD, McDonald SD. Vitamin D deficiency and depression in adults: systematic review and meta-analysis. Br J Psychiatry. 2013 Feb;202:100-7.Berridge MJ. Vitamin D and Depression: Cellular and Regulatory Mechanisms. Pharmacol Rev. 2017 Apr;69(2):80-92. doi: 10.1124/pr.116.013227. PMID: 28202503.C Geng, AS Shaikh, W Han, D Chen, Y Guo and P Jiang., Vitamin D and depression: mechanisms, determination and application. Asia Pac J Clin Nutr 2019;28(4):689-694Okereke OI, Reynolds CF 3rd, Mischoulon D, Chang G, Vyas CM, Cook NR, Weinberg A, Bubes V, Copeland T, Friedenberg G, Lee IM, Buring JE, Manson JE. Effect of Long-term Vitamin D3 Supplementation vs Placebo on Risk of Depression or Clinically Relevant Depressive Symptoms and on Change in Mood Scores: A Randomized Clinical Trial. JAMA. 2020 Aug 4;324(5):471-480.Kocot, J., Luchowska-Kocot, D., Kiełczykowska, M., Musik, I., & Kurzepa, J. (2017). Does Vitamin C Influence Neurodegenerative Diseases and Psychiatric Disorders?. Nutrients, 9(7), 659.

Ana Elisa Barioni faz mestrado em física na UNICAMP. Ela estuda osciladores acoplados de Kuramoto e sua aplicação em neurosciência. Conversamos sobre neurônios como osciladores, grau de sincronização, como soluções não dependem da dimensionalidade das oscilações, entre outras coisas. 25 de fevereiro de 2021

Według różnych danych, zaburzeń depresyjnych doświadcza 1-1,5 mln Polaków. Według WHO, depresja dotyka ponad 264 mln osób na całym świecie. To są jednak dane z 2017 i początku 2020 roku, jeszcze przed wybuchem pandemii koronawirusa, która — nie oszukujmy się — wpłynęła na wszystkich negatywnie, głównie z powodu poczucia niepokoju, izolacji społecznej. Z kolei, według raportu ONZ dotyczącego związku COVID-19 ze zdrowiem psychicznym, pandemia może jeszcze pogorszyć te statystyki, które i tak nie były optymistyczne. Mamy problem ze zdrowiem psychicznym i tym bardziej zatrważa dostępność do specjalistów ds. zdrowia psychicznego - zgodnie z raportem ONZ, w skali świata, na każde 10 tys. osób przypada mniej niż 1 specjalista ds. zdrowia psychicznego. Co z tym można zrobić? Jedną z rzeczy, które mają wpływ na nasz nastrój i w tym na rozwój zaburzeń depresyjnych ma dieta. W tym odcinku skupiam się na związku diety z rozwojem zaburzeń depresyjnych. Nie skupię się jednak na przyczynach depresji czy innych zaburzeń nastroju, bo jest ich wiele, a ja nie mam takiej wiedzy żeby tutaj się mądrzyć z pozycji eksperta. Nawiążę do kwestii osi mózg-jelito, jelito-mózg, o której mówiłam w poprzednim odcinku (#20.) i zachęcam do odsłuchania. Jeżeli masz pytania do tego odcinka napisz do mnie na malgorzata@pielichowska.pl Odwiedź moją stronę: https://pielichowska.pl Zostań moim patronem: https://patronite.pl/pielichowska Odwiedź mojego Facebooka: https://www.facebook.com/pielichowska.dietetyk Odwiedź mojego Instagrama: https://www.instagram.com/diet.and.mindfulness/ Literatura: Marx W., Lane M., Hockey M., i wsp. Diet and depression: exploring the biological mechanisms of action. Molecular Psychiatry, Nov 2020.Firth J., Marx W., Dash S. I wsp., The Effects of Dietary Improvement on Symptoms of Depression and Anxiety: A Meta-Analysis of Randomized Controlled Trials. Psychosomatic Medicine (2019) 81 (5): 265-280. Lassale C, Batty GD, Baghdadli A, Jacka F, Sánchez-Villegas A, Kivimäki M, Akbaraly T. Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies. Mol Psychiatry. 2019 Jul;24(7):965-986.Li Y, Lv MR, Wei YJ, Sun L, Zhang JX, Zhang HG, Li B. Dietary patterns and depression risk: A meta-analysis. Psychiatry Res. 2017 Jul; 253:373-382.Zheng L, Sun J, Yu X, Zhang D. Ultra-Processed Food Is Positively Associated With Depressive Symptoms Among United States Adults. Front Nutr. 2020 Dec 15;7:600449.Liu RT, Walsh RFL, Sheehan AE. Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials. Neurosci Biobehav Rev. 2019 Jul;102:13-23.https://www.foundmyfitness.com/topics/bdnf Olajossy M., Olajossy B., Wnuk S., i wsp. Stężenia kwasu kynureninowego w surowicy krwi pacjentów leczonych elektrycznie z rozpoznaniem zaburzenia depresyjnego nawracającego i depresji w przebiegu choroby afektywnej dwubiegunowej oraz zaburzenia schizoafektywnego. Psychiatr. Pol. 2017; 51(3): 455–468Aly J., Engmann O. The Way to a Human's Brain Goes Through Their Stomach: Dietary Factors in Major Depressive Disorder. Front. Neurosci. (2020) 14:582853. https://www.un.org/sites/un2.un.org/files/un_policy_brief-covid_and_mental_health_final.pdfhttps://zdrowedane.nfz.gov.pl/pluginfile.php/266/mod_resource/content/1/nfz_o_zdrowiu_depresja.pdf

Wydawać by się mogło, że mózg jest jeden i to ten właśnie narząd odpowiedzialny jest za przetwarzanie informacji, samopoczucie czy zachowanie. Okazuje się, że co nieco — a może i nawet więcej niż co nieco — mają do powiedzenia jelita i mikrobiota jelitowa. Ich wpływ na mózg i cały organizm jest ważny do tego stopnia, że określa się je jako „drugi mózg”. Co to oznacza? W tym odcinku wyjaśnię, dlaczego jelita określane są drugim mózgiem, co do pracy "mózgów" mają bakterie, wirusy i grzyby, w jaki sposób nasze „mózgi” komunikują się ze sobą, a także jaki wpływ na zdrowie fizyczne i mentalne ma zaburzenie tej komunikacji. Zapraszam do słuchania. Jeżeli masz pytania do tego odcinka napisz do mnie na malgorzata@pielichowska.pl Odwiedź moją stronę: https://pielichowska.pl Zostań moim patronem: https://patronite.pl/pielichowska Odwiedź mojego Facebooka: https://www.facebook.com/pielichowska.dietetyk Odwiedź mojego Instagrama: https://www.instagram.com/diet.and.mindfulness/ Literatura: Liang S, Wu X and Jin F. Gut-Brain Psychology: Rethinking Psychology From the Microbiota–Gut–Brain Axis. Front. Integr. Neurosci. (2018) 12:33.; Cryan J.F. i wsp. The Microbiota-Gut-Brain Axis (2019) Physiol Rev 99: 1877–2013; Liddle R.A., Parkinson's Disease from the Gut. Brain Res. (2018) August 15; 1693: 201–206.

Cześć! W dzisiejszym odcinku dowiesz się co można robić na najwyższej górze świata (i nie chodzi nam tylko o jej zdobycie), czy Adrian planuje dołączyć do sekty i co zachęca go do zdobycia Śnieżki w samych szortach! Ponadto rozmawiamy o tym jak to jest się nie bać, jak długo człowiek może wytrzymać w kąpieli lodowej (jak tylko zrobi ten jeden prosty trick... a właściwie to trzy), a także co wspólnego ma poznawanie mózgu i zderzanie samochodów! Odcinek zawiera śladowe ilości zmiany biegów. Do usłyszenia! Adrian o Mount Everest, wpływie wysokości na organizm człowieka i metodzie Wima Hoffa: 1:04:05 Patryk o pacjentce SM-046: 11:48 Źródła internetowe: https://www.wimhofmethod.com www.youtube.com/watch?v=VaMjhwFE1Zw&list=WL&index=49&t Bibliografia M. P. W. Grocott et al., N. Engl. J. Med. 360, 2009, 140-149 T. O. Nelson et al., J Exp. Psychol. Gen. 119, 1990, 367-374 J. Ke et al., Exerc. Sport Sci. Rev. 14, 1986, 269-302 J. B. West, J. Appl. Physiol. 102, 1985, 2398-2399 O. Muzik, NeuroImage 172, 2018, 632-641 M. Kox, Proceedings of the National Academy of Sciences 111, 2014, 7379-7384 R. Adolphs et al., Nature 372, 1994, 669-672 R. Adolphs et al., J. Neurosci. 15, 1995, 5879-5891 R. Adolphs et al., Nature 393, 1998, 470-474 J.S. Feinstein et al., Curr Biol. 21, 2011, 34-38 J.S. Feinstein et al., Nat. Neurosci. 16, 2013, 270-272 D. Tranel et al., Cogn. Neuropsychiatry 11, 2006, 219-232

Neuroscientist Amy Belfi recommends “White Matter Correlates of Musical Anhedonia: Implications for Evolution of Music” by Loui, Patterson, Sachs, Leung, Zeng, and Przysinda, published in Frontiers in Psychology (2017). Amy and Finn interview Prof. Psyche Loui about this study, its relevance to theories of the evolution of music, and music anhedonia more broadly. Show notes Recommended article: Loui P, Patterson S, Sachs ME, Leung Y, Zeng T and Przysinda E (2017) White Matter Correlates of Musical Anhedonia: Implications for Evolution of Music. Front. Psychol. 8:1664. doi: 10.3389/fpsyg.2017.01664 Interviewee: Prof. Psyche Loui, Department of Psychology, Program in Neuroscience and Behavior, Wesleyan University Co-host: Prof. Amy Belfi, Department of Psychological Science, Missouri University of Science and Technology Papers cited in the discussion: Altenmüller, E., Kopiez, R., and Grewe, O. (2013a). “A contribution to the evolutionary basis of music: lessons from the chill response,” in The Evolution of Emotional Communication: From Sounds in Nonhuman Mammals to Speech and Music in Man, eds E. Altenmüller, S. Schmidt, and E. Zimmermann (Oxford: Oxford University Press), 313–335. Belfi, A. M., Evans, E., Heskje, J., Bruss, J., and Tranel, D. (2017). Musical anhedonia after focal brain damage. Neuropsychologia 97, 29–37. doi: 10.1016/j.neuropsychologia.2017.01.030 Brielmann, A. A., & Pelli, D. G. (2017). Beauty requires thought. Current Biology, 27(10), 1506-1513. Mas-Herrero, E., Marco-Pallares, J., Lorenzo-Seva, U., Zatorre, R. J., and Rodriguez-Fornells, A. (2013). Individual differences in Music Reward experiences. Music Percept. 31, 118–138. doi: 10.1525/mp.2013.31.2.118 Sachs, M. E., Ellis, R. J., Schlaug, G., and Loui, P. (2016). Brain connectivity reflects human aesthetic responses to music. Soc. Cogn. Aect. Neurosci. 11, 884–891. doi: 10.1093/scan/nsw009 Time Stamps [0:00:10] Intro with Amy Belfi [0:15:15] Interview: Where this study comes from [0:20:12] Interview: Components of research project [0:31:47] Interview: Results [0:44:55] Interview: Implications [0:59:05] Closing with Amy Belfi Credits The So Strangely Podcast is produced by Finn Upham, 2018. The closing music includes a sample of Diana Deutsch's Speech-Song Illusion sound demo 1.