Podcasts about hypoxic

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This episode covers hypoxic-ischaemic encephalopathy.Written notes can be found at https://zerotofinals.com/paediatrics/neonatology/hie/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

Posting tomorrow..Not all cardiac issues have to do with the heart.

In this powerful episode honoring HIE Awareness Month, Neonatal Nurse Practitioner Jessica Fulton shares the raw and emotional story of her son Bo's birth — a delivery marked by unexpected complications that led to a diagnosis of Hypoxic-Ischemic Encephalopathy (HIE). Jessica opens up about what it was like to watch her own son become a critical patient in the very NICU where she had worked for years — as her personal and professional worlds suddenly collided. She speaks candidly about the shocking helplessness she felt as a parent, despite her medical background, and the lifelong challenges that continue to follow: a cerebral palsy diagnosis, fierce advocacy, intensive therapies, emotional isolation, and the realities of parenting a child with complex needs. This episode is a must-listen for NICU parents, healthcare providers, and anyone supporting a family navigating the lifelong impact of HIE. Dr. Brown's Medical: https://www.drbrownsmedical.com Our NICU Roadmap: A Comprehensive NICU Journal: https://empoweringnicuparents.com/nicujournal/ NICU Mama Hats: https://empoweringnicuparents.com/hats/ NICU Milestone Cards: https://empoweringnicuparents.com/nicuproducts/ Newborn Holiday Cards: https://empoweringnicuparents.com/shop/ Empowering NICU Parents Show Notes: https://empoweringnicuparents.com/shownotes/ Episode 68 Show Notes: https://empoweringnicuparents.com/episode68 Empowering NICU Parents Instagram: https://www.instagram.com/empoweringnicuparents/ Empowering NICU Parents FB Group: https://www.facebook.com/groups/empoweringnicuparents Pinterest Page: https://pin.it/36MJjmH

In this episode of Run the Riot, we catch up with an incredible ultrarunner and returning guest — Amanda Lynch! It's been a few years since Amanda last joined us, and she's been busy stacking up strong finishes and incredible experiences. From winning first female at the Loup Garou 100 to tackling technical trails at Lovit 100, Amanda has stayed consistent, positive, and resilient. We dive deep into her racing adventures — from the rocky, rolling terrain of Southern States 200 to her methodical preparation for the upcoming Western States 100. Amanda shares practical lessons about training smarter (with the help of hypoxic masks!), fueling smarter, and racing with grit and joy through every challenge. If you're passionate about trail running, ultra racing, and seeing what's possible with dedication and positivity, this episode is packed with insight and inspiration. Topics Covered: Amanda's journey to finishing her first 200-mile race at Southern States 200 Nutrition strategies for ultra racing and long-distance trail running Training smart with hypoxic simulation for altitude performance Lessons learned from Loup Garou 100, Lovit 100, and Mohican 100 Managing physical challenges like swollen feet and nighttime navigation Mental strategies for pushing through deep fatigue in 200+ mile races Preparing for the legendary Western States 100 Click here for full episode notes and video! Magic Mind Go to http://mm.runtheriot.run and Use Code: RUNTHERIOTAPR

Refractory hypoxemia in the intubated patient is one of the scariest situations any emergency physician can face. In this episode of EMRA*Cast, Drs. Peter Lorenz and Steven Haywood discuss a stepwise approach to managing this worst-case scenario.

In this episode of Autism for Badass Moms, we sit down with Allysa Parker, a dedicated Certified Dental Assistant and fierce advocate for her 6-year-old son, Julian. Julian was diagnosed with Hypoxic Ischemic Encephalopathy (H.I.E.) just two days after birth and later received an Autism diagnosis at 4.5 years old. Navigating these diagnoses has been an emotional rollercoaster for Allysa, bringing moments of helplessness and anxiety. But through it all, she has remained committed to ensuring Julian experiences the world to the fullest. Now, Allysa is using her journey to empower other moms, sharing her insights on H.I.E. and Autism while building a community of support and encouragement. Tune in to hear Allysa's incredible journey. Follow her journey on Instagram: https://www.instagram.com/lovely.loveable.leo/ Don't forget to subscribe and stay tuned for more empowering stories like Allysa's. Follow Us: Instagram: https://www.instagram.com/theabmpodcast/ Facebook: https://www.facebook.com/profile.php?id=100095054651586

#476 What's in a swim stroke? Welcome Welcome to Episode #476 of the 303 Endurance Podcast. We're your hosts Coaches Rich Soares and April Spilde. Thanks for joining us for another week of endurance news, coaching tips and discussion.   February is our month to focus on swimming and I thought the highlight of today's show should be the Ask A Coach section. The question everyone asks is - “How can I improve my swim stroke?” We are going to talk about what that is today and the answer is going to blow your mind!    Heck yes! I couldn't agree more. The swim is oftentimes the barrier to entry for a lot of beginner triathletes and those who are interested in this sport. So, the timing of this topic couldn't be more perfect as most of us are gearing up for our next season!   But first, I'm bringing back the Dad joke…What do a dentist and a swim coach have in common?   Show Sponsor: UCAN UCAN created LIVSTEADY as an alternative to sugar based nutrition products. LIVSTEADY was purposefully designed to work with your body, delivering long-lasting energy you can feel. Whether UCAN Energy Powders, Bars or Gels, LIVSTEADY's unique time-release profile allows your body to access energy consistently throughout the day, unlocking your natural ability to finish stronger and recover more quickly!    In Today's Show Announcements Ask a Coach: What's the most important part of the swim stroke? Get Gritty Tip: The Power of a Misogi Challenge TriDot Workout of the Week - CSS Assessment: What, how, and why? Fun Segment: Like It, Love It, Leave It (Pool Edition)     Announcements:   FulGaz Virtual Group Ride Schedule - We are riding February 1st and we are riding the Pikes Peak ride on our FulGaz Virtual Group Ride.  Link to FulGaz Ride: Quick Start - FulGaz Group Code: 830238 Link to Teams: https://teams.microsoft.com/dl/launcher/launcher.html?url=%2F_%23%2Fl%2Fmeetup-join%2F19%3Ameeting_ZjkyYjc2ZTktYTNmOC00OTliLWE5NTItMGM5ZGRiMzI1MWEx%40thread.v2%2F0%3Fcontext%3D%257b%2522Tid%2522%253a%2522b66709e9-1b6a-4649-a18d-017b8a4b8aa7%2522%252c%2522Oid%2522%253a%2522a731b547-aa9a-4990-a6bc-527e8ce60a7e%2522%257d%26anon%3Dtrue&type=meetup-join&deeplinkId=ed09915f-7770-4919-8ef2-058af0139cdf&directDl=true&msLaunch=true&enableMobilePage=true&suppressPrompt=true   Join us on this FulGaz Ride. Start Here: https://fulgaz.com/quick-start/ 1 JOIN & DOWNLOAD FULGAZ Create an account to activate your 14-day FREE trial.  Then download the FulGaz from your favourite app store. FulGaz is compatible with iOS, Android, Windows, Apple TV or Mac. To see if your device is compatible with FulGaz check out our guide.   2 Connect your trainer Simply open FulGaz, hit “Get Started,” and then connect your devices via the button at the top of the homepage.   FulGaz is compatible with most smart trainers and smart bikes, speed sensors, and heart rate monitors. To see if your trainer is compatible, check out our guide.   QUICK START GUIDE 3 Let's ride With 2,000+ rides and new ones added weekly, there is something for every level of cyclist. Search for iconic rides or by country, time and difficultly.  Our NEW and TRENDING collections are also a great place to start.   Be social and join us on Teams too - https://teams.microsoft.com/dl/launcher/launcher.html?url=%2F_%23%2Fl%2Fmeetup-join%2F19%3Ameeting_ZjkyYjc2ZTktYTNmOC00OTliLWE5NTItMGM5ZGRiMzI1MWEx%40thread.v2%2F0%3Fcontext%3D%257b%2522Tid%2522%253a%2522b66709e9-1b6a-4649-a18d-017b8a4b8aa7%2522%252c%2522Oid%2522%253a%2522a731b547-aa9a-4990-a6bc-527e8ce60a7e%2522%257d%26anon%3Dtrue&type=meetup-join&deeplinkId=ed09915f-7770-4919-8ef2-058af0139cdf&directDl=true&msLaunch=true&enableMobilePage=true&suppressPrompt=true   303 Webinar Series Continues - February 4th 6-7 TriDot Pool School. We have Coach Brandy Ramirez to take us though the program and where you can find a TriDot Pool School near you!   Announcing Coaches Corner (aka Office Hours) with Coaches April Spilde and Rich Soares. Every 3rd Tuesday of the month. Link to Feb. 18 Coaches Corner - link   Upcoming Programming - Our February focus will be on swimming. Feb. 1 - FASST and essential pool equipment Feb. 8 - Webinar with TriDot Pool School Director, Coach Brandy Ramirez Feb. 15 - How to Read Swim Workout Feb. 22 - Open Water Skills   Grit2Greatness Coaching Facebook Page Live - Come check out our new coaching Facebook page @grit2greatnessendurance Ask A Coach Sponsor: G2G Endurance Triathletes, stop guessing and start progressing! At Grit2Greatness Endurance Coaching, we've teamed up with TriDot to take the trial and error out of your training. Personalized workouts, next-level analytics, and seamless onboarding—it's all built to make you better, faster. Try it for two weeks FREE, then keep going for as little as $14.99 a month. The right training plan can change everything. Ready to see how far you can go? Click one of the sign-up links in our show notes today!  Ask A Coach: What's the most important part of the swim stroke? Hint, it's not the stroke. It's F.A.S.S.T. Setup (Rich): Swimming 101 in college, private in-pool lessons, professional assessments with video and coaches (eg, Swim Labs), reading books, Total Immersion, the pro in the lane next - these are all some of the ways that I tried to improve my swimming technique and form.    In July of 2022, I was invited to Dallas with the TriDot coaches at that time to pilot the TriDot Pool School. This was a program that had been in development for years and the coaches were going to be the students/subjects.   The greatest problems to overcome are drag and balance. At the core of the program is the foundation of the swim position that occurs between strokes. In fact, this program spends 90% of its focus on that position between strokes and maybe 10% on the stroke itself.   We are going to introduce the components of this position which we affectionately call F.A.S.S.T. Fingers flat and forward Arm stretched straight Shoulders and hips at 45 degrees Spine aligned from tail to crown with head facing down Thumb to thigh with palm to sky To really learn the FASST method, it helps to have long blade fins, snorkel and nose clips. Here are some links to what I generally suggest and are common at the pool schools. Amazon.com : Speedo Unisex-Adult Swim Training Fins : Sports & Outdoors Amazon.com : Speedo unisex adult Swim Training Bullet Head diving snorkels, Shocking Lime, One Size US : Sports & Outdoors Amazon.com : TYR Ergo Swimclip - Black : Nose Plugs : Sports & Outdoors   The nose clips are to keep water out of your nose while using the snorkel.   Get Gritty Tip: The Power of a Misogi Challenge What if you did something so difficult, so uncertain, that there was a real chance you might fail? That's the essence of *Misogi*—an ancient Japanese practice redefined by modern thinkers as a way to push boundaries, build resilience, and redefine what's possible.   The rule? Pick a challenge so big and audacious that there's at least a 50% chance you won't succeed. It should be something far outside your comfort zone, forcing you to confront your limits—and then go beyond them.   For multi-sport athletes, a *Misogi* isn't just about physical endurance. It's about mental toughness, adaptability, and proving to yourself that you're capable of more than you think. Maybe it's your first ultra-distance event, a self-supported adventure, or a challenge that removes the usual metrics and expectations.   For the everyday human? A *Misogi* might mean committing to something that genuinely scares you—signing up for a triathlon when you don't see yourself as an athlete, tackling a project at work that feels beyond your skillset, or even showing up in a space where imposter syndrome tells you you don't belong.   Here's the truth: You don't grow by doing what you already know you can do. Growth happens when you face uncertainty and decide to take the leap anyway.   So, what's *your* Misogi for 2025?     TriDot Workouts of the Week:  To kickoff our February theme on swimming, let's start with a TriDot Swim workout. Since this is an Assessment Week for both April and I, we thought we'd share the Critical Swim Speed assessment. We'll explain what the session is, how to pace it for your best results, how to calculate your Critical Swim Speed and how to track your progress. Warmup 4 x 25 Kicking With or Without Fins (15 sec) 4 x 25 FASST with Breathing (15 sec) 4 x 25 Pinocchio-Glove (15 sec) 4 x 25 FASST-1-FASST (15 sec) 4 x 25 Finger-Tip Drag Drill (15 sec) 4 x 25 Full Stroke Swimming Build to Z4 (15 sec)     Main Set 200 swim starting slow and gradually building pace from Z2 to Z4 for final 50; rest 2 min 1. Perform a 400 time trial effort from a push (not dive). 2. Recover for 10 to 15 minutes with easy swimming and rest. 3. Perform a 200 time trial effort from a push. Be sure to count your laps correctly. Your 400 time should not be faster than twice your 200 time. Balance of time @ Z2 with excellent form Be sure to enter/confirm your assessment results to update your training intensities and race projections.     Cool Down Balance of time @ Z2 and/or repeat warm up drills as time permits. How to calculate your CSS? Critical Swim Speed (CSS) is a measure of a swimmer's aerobic capacity and is calculated using the following formula: CSS (m/sec) = 200 / (time taken for 400m – time taken for 200m). CSS in meters per second can also be calculated using the following formula: CSS (m/sec) = (D2 - D1) ÷ (T2 - T1), where D1 = 50, D2 = 400, T1 = time for 50m swim in seconds and T2 = time for 400m swim in seconds. Swimming fast can be simplified into a physics equation: (S)peed = Stroke (L)ength x Stroke (R)ate. How to track your CSS? Use TriDot and let it do it automatically. Plus keep a SwimDot score of your percentile ranking, normalized and banded to show you against your peers. Keep a spreadsheet and build this formula into it.  We are happy to email you the CSS Logbook which includes a way to track what your 400 and 200 paces were, the ratio between the two and more. Simply go to the G2G Contact Us Page and send with the subject line CSS and we will get that right over to you. Guess what, Rich! It's that special time of the show where we have some fun as I take you through some fun and maybe, “not-so fun dilemmas.” It's time for…!  Today's Fun Segment: Like It, Love It, or Leave It! (Pool Edition) How It Works: You give your guest three pool-related training experiences. They must "Like It" (it's fine), "Love It" (can't get enough), or "Leave It" (never again!) by assigning one to each category. 1. Lane Etiquette Dilemmas Swimming with someone who constantly touches your feet Circle swimming with five strangers in a lane Getting stuck behind a slow swimmer with no passing room 2. Swim Gear Struggles Goggles that fog up mid-set A swim cap that keeps slipping off Wearing a wetsuit in the pool for “race simulation” 3. Pool Training Drills Endless kickboard drills Hypoxic breathing sets (fewer breaths per lap) Sighting practice in the pool (aka, looking like a dolphin) 4. Post-Swim Realities Smelling like chlorine for the rest of the day That intense hunger that hits 10 minutes after getting out Wet hair dripping down your back no matter how well you towel off 5. Annoying Pool Habits The person who sprints past you, then immediately slows down Mid-lane conversations that block the wall when you're trying to turn Someone doing butterfly in a crowded lane 6. Swim Set Preferences 10x100s on a tight interval A long, slow continuous swim IM (individual medley) even though you're only here for freestyle 7. Unexpected Pool Hazards That mystery warm spot in the water Hairballs floating toward you mid-lap The moment your goggles snap right before the main set   Closing: Thanks again for listening this week.  Please be sure to follow us @303endurance and of course go to iTunes and give us a rating and a comment.  We'd really appreciate it! Stay tuned, train informed, and enjoy the endurance journey! Train With Coach Rich: Coach Rich Soares Rich.soares@tridot.com Rich Soares Coaching TriDot Signup - https://app.tridot.com/onboard/sign-up/richsoares RunDot Signup - https://app.rundot.com/onboard/sign-up/richsoares   Train with Coach April: Coach April Spilde April.spilde@tridot.com Grit2Greatness Endurance Podcast Podcast Series - Apple Podcasts TriDot Signup - https://app.tridot.com/onboard/sign-up/aprilspilde Triathlon Fun Segments: Would You Rather? Ironman Confessions Like It, Love It, Leave It Transition Troubles   Shoutouts to: @genucan @grit2greatnesscoaching @ironmantri @303triathlon @tridottraining @tridottrainingsystem #grit #grit2greatness #usatriathlon #wintertriathlon #breckenbiener  #ironmantri #cycling #triathlon #swimbikerun #Iamtridot #tridotambassador #tridotcoach

On this week's listener episode, we welcome Sarah. Sarah shares her two birth experiences with us. Her first pregnancy resulted in an undetected infection and meconium aspiration, which led to her daughter's hypoxic-ischemic encephalopathy (HIE) diagnosis.  Sarah also shares about her subsequent pregnancy and birth which she describes as part of her healing.On this episode, you will hear:- Maternal infection - Meconium aspiration- Hypoxic-ischemic encephalopathy (HIE)- NICU journey- Healing and support: finding community- Second birth experience as redemptive - Advocacy and intuition You can find Sarah on Instagram: @Sarahber88If you have a birth trauma story you would like to share with us, click this link and fill out the form. For more birth trauma content and a community full of love and support, head to my Instagram at @thebirthtrauma_mama.Learn more about the support and services I offer through The Birth Trauma Mama Therapy & Support Services.

Premium Podcast Access. Click below ⁠https://www.patreon.com/perfecthealth⁠ Learn more: ⁠https://perfecthealthlesson.com/ Episode Summary:In this episode of The New Science of Physical Health, host Shane Stubbs dives deep into the science of fat loss, VO₂ max, and hypoxic exercise. Discover how shedding excess fat impacts not only aesthetics but also overall well-being by boosting energy, reducing chronic disease risk, and improving physical performance. Shane also explains the critical role of mitochondria in fat metabolism and shares actionable strategies for tracking key health metrics that can enhance your heart health and longevity. Why Fat Loss Matters Fat loss isn't just about looking better—it's about feeling better, improving energy levels, reducing joint pain, and lowering the risk of chronic diseases. Shane explains the molecular process of fat loss, focusing on how triglycerides are broken down and used for energy in the mitochondria. The Science of Fat Loss Hormone-sensitive lipase (HSL) triggers the breakdown of triglycerides into glycerol and fatty acids. These fatty acids undergo beta-oxidation in the mitochondria, producing ATP, water, and carbon dioxide. The importance of creating a caloric deficit and how it facilitates fat loss is discussed in detail. Raising Your VO₂ Max VO₂ max is a critical fitness metric, indicating how much oxygen your body can utilize during intense exercise. Shane shares strategies to improve your VO₂ max through interval training and aerobic exercises, emphasizing the importance of consistency. Learn why individuals with high VO₂ max levels tend to live longer and have healthier cardiovascular systems. Tracking Blood Biomarkers Shane highlights six key blood biomarkers you should monitor, including: Proactively tracking these markers helps detect early signs of heart disease and diabetes, allowing for timely intervention. Coronary Calcium Score Testing By age 40, Shane recommends getting a Coronary Calcium Score test—a non-invasive scan that measures plaque buildup in your coronary arteries. Early detection can lead to life-saving interventions, and Shane explains why this test is a must for proactive heart health. Addressing Insulin Resistance and Weight Challenges Shane discusses the link between insulin resistance, metabolic syndrome, and weight gain. He encourages listeners to explore pharmacological options such as GLP-1 agonists in consultation with a healthcare professional for managing excess weight and improving metabolic health. The Power of Lifelong Learning Staying informed is key to long-term health. Shane advises seeking evidence-based information from reputable sources and staying curious about new developments in health science. Hypoxic Exercise – The Oxygen Deficit Advantage Shane explains the concept of hypoxic training, which involves exercising in a low-oxygen environment to trigger unique physiological adaptations. Benefits include increased red blood cell production, enhanced mitochondrial efficiency, improved cardiovascular health, and greater fat oxidation. Learn about the science of hypoxia-induced metabolic adaptations and how they can boost fat loss and fitness If you enjoyed this episode and want to unlock more exclusive content, visit our Patreon link in the show notes or head to PerfectHealthLesson.com. Your support helps us continue to deliver cutting-edge health education and personalized guidance to help you achieve your best physical health! Don't forget to subscribe, leave a review, and share this episode with someone who's ready to take control of their health.

Send us a Text Message.Response categorization and outcomes in extremely premature infants born at 22-26 weeks gestation that received inhaled nitric oxide for hypoxic respiratory failure.Boly TJ, Dagle JM, Klein JM, Rios DR, McNamara PJ, Giesinger RE.J Perinatol. 2023 Mar;43(3):324-331. doi: 10.1038/s41372-022-01582-4. Epub 2022 Dec 12.PMID: 36509816 Free PMC article.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode, listen to our editorial apprentice, Dr. Eric Peeples describe the scope and importance of our collection on neonatal encephalopathy and hypoxic-ischemic encephalopathy.Visit the collection here: Neonatal Encephalopathy and Hypoxic Ischemic Encephalopathy (nature.com) Hosted on Acast. See acast.com/privacy for more information.

Don't Face Cancer Alone"The 6 Pillars of Healing Cancer" workshop series provides you valuable insights and strategies to support your healing journey - Click Here to Enroll  Can Breathing Less Oxygen Actually Improve Your Health?Dr. Katie Deming sits down with Dr. Ark Prokopov, a leading expert in the field of mitochondrial function and hypoxia. Dr. Prokopov explains that when you breathe in less oxygen, your body has to work harder to produce energy. Over time, this training makes your mitochondria stronger and more efficient.From boosting your mitochondrial function and enhancing your body's natural defenses, to potentially complementing conventional treatments for conditions like cancer and Lyme disease, the benefits of intermittent hypoxic training are vast and promising. Chapters:08:11 Growing Age Leads to Accumulation of Damaged Mitochondria13:25 Lyme Disease Treatment21:24 Why Bowhead Whales Living Exceptionally Long Lives28:21 Optimize Cancer Radiation Treatment38:31 Negative Effects of Tent Sleeping Imagine if you could tap into the same powerful adaptations that allow elite athletes to push their bodies to the limit, all from the comfort of your own home. Dr. Prokopov breaks down the science behind this fascinating approach, sharing insights gained from his extensive research and clinical experience.Listen and learn how by challenging our bodies with controlled periods of low oxygen, we can unlock our own natural abilities to heal, adapt, and thrive.Learn More About Dr. Prokopov's Work:  https://oxyesta.com/Send us a Text Message.Don't Face Cancer Alone"The 6 Pillars of Healing Cancer" workshop series provides you valuable insights and strategies to support your healing journey - Click Here to Enroll MORE FROM KATIE DEMING M.D. Take a Deeper Dive into Your Healing JourneyFollow Dr. Katie Deming's Substack HereJoin Dr. Katies Free Workshop: Your Roadmap to Radiant Health Work with Dr. Katie:www.katiedeming.comFollow Dr. Katie Deming on Instagram:The.Conscious.OncologistPlease Support the Show Share this episode with a friend or family member Give a Review on Spotify Give a Review on Apple Podcast DISCLAIMER:The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose, treat, cure, or prevent any disease without consulting your healthcare provider.

Moderator: James P. Rathmell, M.D. Participants: Albert Dahan, M.D., Ph.D., and Thomas K. Henthorn, M.D. Articles Discussed: Reversal of Propofol-induced Depression of the Hypoxic Ventilatory Response by BK-channel Blocker ENA-001: A Randomized Controlled Trial Reversal for Respiratory Depression: Let's Take a Breath! Transcript

Elena Conser is a third year PhD student in the Plankton Ecology Lab within the Department of Integrative Biology. She really, really, loves plankton – marine organisms that are unable to swim against the current and are thus, at the whim and mercy of their environment. To study plankton, Elena employs a cutting-edge technology imaging system to view plankton in their natural environment, something that has not previously been possible in her field. (Disclaimer: this episode was recorded with a backup system so the audio quality is somewhat below the usual). Hosted by Matt Vaughan and Joseph Valencia.

Esophageal versus Rectal Temperature Monitoring during Whole-body Therapeutic Hypothermia for Hypoxic-ischemic Encephalopathy: Association with Short and Long-term Outcomes. Wu TW, Schmicker R, Wood TR, Mietzsch U, Comstock B, Heagerty PJ, Rao R, Gonzalez F, Juul S, Wu YW.J Pediatr. 2024 Feb 1:113933. doi: 10.1016/j.jpeds.2024.113933. Online ahead of print.PMID: 38309524 Free article. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Hello Friends, We have a new episode of journal club for you this week. On this episode Ben & Daphna review the latest research in neonatology, and welcome the EBNEO team for a new commentary. The articles reviewed this week include: Esophageal versus Rectal Temperature Monitoring during Whole-body Therapeutic Hypothermia for Hypoxic-ischemic Encephalopathy: Association with Short and Long-term Outcomes. Wu TW, Schmicker R, Wood TR, Mietzsch U, Comstock B, Heagerty PJ, Rao R, Gonzalez F, Juul S, Wu YW.J Pediatr. 2024 Feb 1:113933. doi: 10.1016/j.jpeds.2024.113933. Online ahead of print.PMID: 38309524 Free article.Neonatal Outcomes After COVID-19 Vaccination in Pregnancy. Norman M, Magnus MC, Söderling J, Juliusson PB, Navér L, Örtqvist AK, Håberg S, Stephansson O.JAMA. 2024 Feb 6;331(5):396-407. doi: 10.1001/jama.2023.26945.PMID: 38319332Maternal syphilis rates tripled in the US between 2016 and 2022, data show. Tanne JH.BMJ. 2024 Feb 15;384:q416. doi: 10.1136/bmj.q416.PMID: 38359912 No abstract available. Therapeutic hypothermia for preterm infants 34-35 weeks gestational age with neonatal encephalopathy. Kim SH, El-Shibiny H, Inder T, El-Dib M.J Perinatol. 2024 Jan 16. doi: 10.1038/s41372-024-01874-x. Online ahead of print.PMID: 38228763Randomised study of a new inline respiratory function monitor (Juno) to improve mask seal and delivered ventilation with neonatal manikins. Tracy MB, Hinder M, Morakeas S, Lowe K, Priyadarshi A, Crott M, Boustred M, Culcer M.Arch Dis Child Fetal Neonatal Ed. 2024 Feb 9:fetalneonatal-2023-326256. doi: 10.1136/archdischild-2023-326256. Online ahead of print.PMID: 38336472Dextrose gel prophylaxis for neonatal hypoglycaemia and neurocognitive function at early school age: a randomised dosage trial. Wei X, Franke N, Alsweiler JM, Brown GTL, Gamble GD, McNeill A, Rogers J, Thompson B, Turuwhenua J, Wouldes TA, Harding JE, McKinlay CJD; pre-hPOD Early School-age Outcomes Study Group.Arch Dis Child Fetal Neonatal Ed. 2024 Feb 12:fetalneonatal-2023-326452. doi: 10.1136/archdischild-2023-326452. Online ahead of print.PMID: 38307710Effect of human milk-based fortification in extremely preterm infants fed exclusively with breast milk: a randomised controlled trial. Jensen, G. B., Domellöf, M., Ahlsson, F., Elfvin, A., Navér, L., & Abrahamsson, T. eClinicalMedicine (2023).Neurodevelopmental Outcomes of Extremely Preterm Infants Fed Donor Milk or Preterm Infant Formula: A Randomized Clinical Trial. Colaizy TT, Poindexter BB, McDonald SA, et al. JAMA. 2024;331(7):582–591. doi:10.1001/jama.2023.27693EBNEO Commentary: De-MIST-ifying the 2-year outcomes of non-invasive surfactant therapy. Loft L, Ferguson KN, Tingay DG. Acta Paediatr. 2024 Jan 25. doi: 10.1111/apa.17116. O As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Welcome back to the Real Health Talk Podcast with Zak and Jordan.Today's episode is our first guest episode with none other than the incredible Eugene Koning. Eugene is a breathwork practitioner who runs both breathwork and meditation at Saint Haven Private Wellness Club. He also runs the Eugene Koning podcast and is one of our best friends.In this episode, we cover - why we should care about breathing, what good breathing looks like, what poor breathing looks like, Wim Hof,  breathwork practices, and much more.Key takeaways include:Becoming aware of your breathBreathe with your noseBreathe lightBreathe into the bellyFollow the LSD method - Light, slow, deepBuild your breathwork toolbox with different breathwork techniques.Products/Resources/People Mentioned:OthershipWim HofRecovery mate nasal strips - zak20 for 20% offLaird HamiltonYes Theory - Wim HoffWaking upThe breath houseYou can find Eugene on Instagram @eugene_koning and check out his podcast at The Eugene Koning Podcast.Stay connected with us, Jordan and Zak, on Instagram. You can find Jordan at @jordan_davey and Zak at @coachzakgoold. We're excited to engage with our community and hear your thoughts.Stay up to date with everything Real Health @real_health_talk. Don't forget to subscribe to our podcast on your preferred platform. If you enjoy our content, please consider leaving a 5-star review. Your feedback is invaluable, and we're eager to hear what resonates with you and what doesn't. Your input helps us tailor our content to your interests and needs.Thank you for tuning in, and let's embark on this journey to real health together.Yours in the best of health.(0:00) Intro(4:36) Introduction to Eugene (9:40) Why should you care about breathing(15:22) Subconscious breathing vs conscious breathing (22:40) Down regulating breath work(24:00) Breathwork techniques with Eugene(30:00) The average person isn't breathing correctly(33:40) Eugene's breath journey(38:51) Finding Wim Hof(44:50) Guided Wim Hof with Eugene(50:20) Build a breathing technique toolkit(55:30) Meditation(59:00) Spiritual breathwork(1:04:00) Functional breath work(1:05:01) Working on improving your breathwork(1:06:40) Hypoxic training(1:15:00) Poor vs good breathing habits (1:18:50) Breathing to brace your core(1:24:15) The harm of mouth breathing (1:28:20) Using the breath to  improve mental health(1:30:40) The levels of breathing(1:33:37) Othership and breathwork techniques(1:35:25) The diaphragm(1:37:31)  Level 3 & 4(1:40:45) What a good day of breathing looks like(1:45:47) The exploratory side of breathing(1:53:23) Surrounding yourself with people who want the best for you(2:00:00) OutroSupport the Show.

Dr. Patricia Graese discusses the diagnosis of delayed post-hypoxic leukoencephalopathy.

Today, we speak with Dr Carling Ursem, an accomplished trail runner from Northern California. Carling specializes in ultra-runs (runs with distances longer than traditional marathon races of 26.2 miles) and holds many FKTs (fastest known times) all over the Sierra mountains. But that's not all, she's also a hard-working oncologist at UCSF, a rock climber, a wife, and is raising two beautiful girls in the coastal town of Marin. In this freewheeling conversation, we dive into Carling's journey into ultra-running, her training routines, diet, and how she manages to have fun with it all! ▶️ YouTube

“Note to a Hypoxic Delusion” by K. Lynn Harrison Manawaker Studio’s Flash Fiction Podcast is supported by patrons on Patreon: http://patreon.com/manawaker/ Contributor Bios: http://www.manawaker.com/flash-fiction-podcast-contributors/ Please consider supporting Manawaker Studio with a purchase of one of our books or games: http://www.manawaker.com Have a piece of fiction to submit to FFP? Check guidelines here: http://www.manawaker.com/ffp-submissions/

Today we give you our second pediatric clinical case with Dr. Sakina Butt.  This time she talks about hypoxic-ischemic injury and low Apgar scores in infants and young children, or “littles” as she endearingly refers to them. Show notes are available at www.NavNeuro.com/129 _________________ If you'd like to support the show, here are a few easy ways: 1) Get APA-approved CE credits for listening to select episodes: www.NavNeuro.com/INS  2) Tell your friends and colleagues about it 3) Subscribe (free) and leave an Apple Podcasts rating/review: www.NavNeuro.com/itunes 4) Check out our book Becoming a Neuropsychologist, and leave it an Amazon rating   Thanks for listening, and join us next time as we continue to navigate the brain and behavior! [Note: This podcast and all linked content is intended for general educational purposes only and does not constitute the practice of psychology or any other professional healthcare advice and services. No professional relationship is formed between hosts and listeners. All content is to be used at listeners' own risk. Users should always seek appropriate medical and psychological care from their licensed healthcare provider.]

Alexey Molchanov is a multi-world record holding and world record breaking freediving athlete and arguably the greatest and most consistent freediving athlete of all time.In this episode we discuss:This is the 150th episode of The Freedive Cafe!Alexey was in Cyprus at the time of recording, preparing for the AIDA World Championships.Alexey's thoughts on the doping accusations against Vitomir Maricic and Petar Klovar and doping in freediving.Is it time for new freediving organisations?Talking about Alexey's competition and how his training has evolved since we last spoke.Questions from patreon supporters Jordy and Matthias about Alexey's base training phase.Question from Zoe about the benefits of swimming for beginner freedivers.How does Alexey train his no fins leg lick?A question from Maurice about recovery protocols.The benefits of active recovery for Alexey's body type.A question from Emile about lung squeeze and how the experience of squeeze has evolved over the years.The importance of developing mobility of the breathing muscles and thoracic cage.A question from Bizo Silva (#137) about a special technique to counter contractions.Hypoxic tolerance and how it evolves over the years.Is no fins the key to improving hypoxic tolerance???What is Alexey's experience with narcosis and does adaptation come over time?A question from Kris about mental preparation before a dive.A question from several patrons about what Alexey thinks his mum would think about the way the freediving world has changed in the last few years.Why does Alexey freedive?

Dr. Martin Gibala is a muscle physiologist, professor, and kinesiology department chair at McMaster University in Hamilton, Ontario, Canada. He is best known for pioneering research on the health benefits of high-intensity interval training (HIIT) and his profound understanding of HIIT's physiological mechanisms. He is a co-author of the book "The One-Minute Workout." In this episode, we discuss: (00:00) Introduction (11:00) What is high-intensity training? (11:53) Zone 2 vs. HIIT for VO2 max — which is better? (13:22) The vital role of vigorous exercise (14:40) Why VO2 max matters for longevity (17:45) Elite athletes vs. committed exercisers (22:09) Measuring maximum heart rate and VO2 max (30:31) How the heart adapts to HIIT to increase VO2 max (35:47) Why vigorous exercise accelerates mitochondrial adaptation (40:06) Enhancing fat oxidation and mitochondrial growth with vigorous exercise (44:22) How intensive exercise boosts fat breakdown (45:56) Is high-intensity exercise better for autophagy than fasting? (58:05) Exercise snacks (1:00:39) Protocol for VO2 max (1:05:50) The effect of HIIT on muscle fiber types (1:10:18) How aging effects muscle fibers (1:14:09) Does high-intensity training produce an “afterburn effect? (1:16:13) Why vigorous workouts are better for BDNF and cognition (1:24:15) Anti-metastatic cancer effects (1:50:23) Wingate training vs. reHIIT — a comparison of protocols (1:55:38) Perceived exertion vs. HRmax (1:59:23) Interval walking for type 2 diabetics (2:01:06) Contraindications of HIIT (2:05:06) Why preconditioning reduces risks from exercise (2:10:44) Can resistance training be a type of aerobic exercise? (2:16:24) Does cardio and strength training interfere with each other? (2:18:45) How many minutes per week of high-intensity training? (2:26:58) Are there sex differences in high-intensity training? (2:26:58) Misconceptions on high-intensity interval training for women (2:27:42) Should post-menopausal women do H.I.I.T.? (2:27:47) Does intense exercise raise cortisol? (2:34:25) Bone density and osteoarthritis (2:36:40) Atrial fibrillation risk (2:32:13) Hypoxic training and blood flow restriction (2:40:45) Tips for training with joint issues

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.31.551394v1?rss=1 Authors: Fernandez-Gonzalez, A., Mukhia, A., Nadkarni, J., Willis, G., Reis, M., Zhumka, K., Vitali, S., Liu, X., Galls, A., Mitsialis, S. A., Kourembanas, S. Abstract: Objective: Macrophages play a central role in the onset and progression of vascular disease in pulmonary hypertension (PH) and cell-based immunotherapies aimed at treating vascular remodeling are lacking. This work evaluates the effect of pulmonary administration of macrophages modified to have an anti-inflammatory/pro-resolving phenotype in attenuating early pulmonary inflammation and progression of experimentally induced PH. Approach and Results: Mouse bone marrow derived macrophages (BMDMs) were polarized in vitro to a regulatory (M2reg) phenotype. M2reg profile and anti-inflammatory capacity were assessed in vitro upon lipopolysaccharide (LPS)/interferon-{gamma} (IFN{gamma}) restimulation, before their administration to 8- to 12- week-old mice. M2reg protective effect was tested at early (2 to 4 days) and late (4 weeks) time points during hypoxia (8.5% O2) exposure. Levels of inflammatory markers were quantified in alveolar macrophages and whole lung, while PH development was ascertained by right ventricular systolic pressure (RSVP) and right ventricular hypertrophy (RVH) measurements. Bronchoalveolar lavage (BAL) from M2reg-transplanted hypoxic mice was collected, and its inflammatory potential tested on naive BMDMs. M2reg macrophages demonstrated a stable anti-inflammatory phenotype upon a subsequent pro-inflammatory stimulus by maintaining the expression of specific anti-inflammatory markers (Tgf{beta}, Il10 and Cd206) and downregulating the induction of proinflammatory cytokines and surface molecules (Cd86, Il6 and Tnf). A single dose of M2regs attenuated the hypoxic monocytic recruitment and perivascular inflammation. Early hypoxic lung and alveolar macrophage inflammation leading to PH development was significantly reduced and, importantly, M2regs attenuated RVH, RVSP and vascular remodeling at 4 weeks post treatment. Conclusion: Adoptive transfer of M2regs halts the recruitment of monocytes and modifies the hypoxic lung microenvironment, potentially changing the immunoreactivity of recruited macrophages and restoring normal immune functionality of the lung. These findings provide new mechanistic insights on the diverse role of macrophage phenotype on lung vascular homeostasis that can be explored as novel therapeutic targets. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Discussion of initial workup, classification and differential diagnosis of hypoxia & Hypoxemic respiratory failure. 1- Please make sure you have the formulas ready in front of you (including PA-O2 formula, O2 delivery, O2 content and Fick's Formulas among others). 2- If you need to pause and repeat do so before moving on (it can save lives ....!)

Skin aging is a natural process that affects everyone as they grow older, however, there are several factors that can accelerate the aging process, including cellular degeneration. Our skin is composed of various types of cells, each playing a crucial role in maintaining its health and appearance. Understanding these cellular mechanisms can help us take steps to slow down the aging process and maintain healthier, more youthful-looking skin. Welcome to another episode of the Biohacking Beauty podcast brought to you by Young Goose Skincare! In this episode, host Amitay Eshel, the CEO of Young Goose, is joined by Dr. Sandra Kaufmann to discuss the cellular causes of skin aging, and her work in developing the Kaufmann protocol. We'll also cover why both internal and external care is necessary for optimizing skin health, and why mixing up your skincare can be beneficial for aging skin. Dr. Sandra Kaufmann began her academic career in the field of cellular biology, earning a Master's Degree from the University of Connecticut in Tropical Ecology and Plant Physiology. Turning to medicine, she received her medical Degree at the University of Maryland, and completed a residency and fellowship at Johns Hopkins in the field of pediatric anesthesiology. For the last five years she has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children's Hospital, a nationally recognized center of excellence. Most recently, she was recognized as “Best in Medicine” by the American Health Council.What we discuss:[00:00] Dr. Sandra Kaufmann's work on cellular degeneration and aging can revolutionize skin care.[06:28] Using molecules to affect aging pathways is the key to longevity.[17:17] Improving skin health requires both internal and external care.[22:12] Lactoferrin can help block Advanced glycation end products (AGEs) and clear them from the skin.[32:31] Mixing up skincare is important for aging skin[37:57] Hypoxic training can enhance mitochondrial function for high altitude climbing.[48:24] Starting a longevity company to provide access to preventive medicine[53:16] Tailored dosing strategy is important for longevity medicines[1:03:40] Hyaluronic acid is an important molecule for skin health.Key Takeaways:When it comes to achieving and maintaining healthy, radiant skin, it's essential to adopt a comprehensive approach that includes both internal and external care. While topical treatments like injectables and Platelet-Rich Plasma (PRP) therapies can enhance skin appearance, internal care through supplements can play a pivotal role in protecting and repairing the skin from damage.As we age, our skin undergoes various changes and requires different approaches to maintain its health and vitality. One effective strategy for aging skin is to mix up your skincare routine. This involves incorporating a range of products and techniques to address different concerns and adapt to the changing needs of your skin.Addressing skin concerns like creepiness requires a combination of internal and external approaches. However, in order to stimulate collagen, it is important to provide the necessary nutrients for fibroblasts, the cells responsible for collagen production. To learn more about Young Goose:Website: https://www.younggoose.com/Instagram: @young_goose_skincareGet 20% off your first purchase by using code PODCAST20 at www.younggoose.comTo learn more about Dr. Sandra Kaufmann:Website: https://kaufmannprotocol.com/Instagram:...

Having made his way through school and started his career as an electrical engineer, skydiving hadn't been much more than a one time experience with a static line jump in college; yet as the real world started to exert itself on him, Mark "Trunk" Kirschenbaum decided to give jumping another go. This time around he could afford to pursue skydiving properly, and quickly found himself not just jumping but filming as well. Back then and especially for a talented electrical engineer, the shortcomings of freefall photography made themselves crystal clear. Luckily for the majority of camera flyers, Trunk had a real knack for exactly this type of problem solving, and the beginnings of his company Hypoxic began to take shape. Now providing camera solutions while still traveling the country and enjoying the boogie life (although a slightly more mellow version) Mark "Trunk" Kirschenbaum and Hypoxic continue to help capture our Lunatic Fringe on video.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.05.01.538334v1?rss=1 Authors: Michno, W. M., Puno, A., Li, L., Everitt, A., McCluskey, K., Birey, F., Htun, S., Nagar, D., Dai, Y., Gurwitz, E., Willsey, J., Pasca, A. M. Abstract: Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.23.537998v1?rss=1 Authors: Zelmer, A. R., Starczak, Y., Solomon, L. B., Richter, K., Yang, D., Atkins, G. J. Abstract: The intracellular infection of osteocytes represents a clinically important aspect of osteomyelitis. However, few human osteocyte in vitro models exist and the differentiation of immature osteoblasts to an osteocyte stage typically takes at least 4-weeks of culture, making the study of this process challenging and time consuming. The osteosarcoma cell line Saos-2 has proved to be a useful model of human osteoblast differentiation through to a mature osteocyte-like stage. Culture under osteogenic conditions in a standard 5% CO2 and normoxic (21% O2) atmosphere results in reproducible mineralisation and acquisition of mature osteocyte markers over the expected 28-35 day culture period. In order to expedite experimental assays, we tested whether reducing available oxygen to mimic concentrations experienced by osteocytes in vivo would increase the rate of differentiation of Saos-2 cells. Cells cultured in a 5% CO2, 1% O2 atmosphere exhibited accelerated deposition of mineral, reaching near saturation by 14 days as demonstrated with the Alizarin Red and Von Kossa staining. The gene expression of the major hypoxia-induced transcription factor HIF1 and the key osteogenic transcription factor RUNX2 were both elevated under 1% O2. Early (COLA1, MEPE) and mature (PHEX, DMP1 and SOST) osteocyte markers were also upregulated earlier under hypoxic compared to normoxic growth conditions. Thus, culture under low oxygen accelerates key markers of osteocyte differentiation, resulting in a useful human osteocyte-like in vitro cell model within 14 days. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Stuart and Carolyn speak with Paris Collingsworth about hypoxia in the Great Lakes. What is it? Why does it happen? Is it bad? Plus: more than you probably knew about midges and the act of forgetting to remember not to forget.Show links:Widespread prevalence of hypoxia and the classification of hypoxic conditions in the Laurentian Great LakesExperimental Lake Erie Hypoxia Forecast Ice Cover, Food, and Hypoxia: How is Climate Change Affecting Great Lakes Fish? | International Joint Commission Joba Chamberlain recalls his bout with the midgesCafecito http://chi.iheartcafecito.com/Sleeping Bear Dunes National Lakeshore (U.S. National Park Service) Norelco Love Hurts adShow credits:Host & Executive Producer: Stuart CarltonCo-Host: Megan GunnSenior Producer: Carolyn FoleyProducers: Hope Charters, Megan Gunn, & Irene MilesAssociate Producer: Ethan ChittyEdited by: Quinn RosePodcast art by: Joel DavenportMusic by: Stuart Carlton

Review the current status of hypothermia treatment for hypoxic-ischemic encephalopathy (HIE).Review other trials of therapeutic hypothermia.Review the results of combining hypothermia with other neuroprotective treatments.Discuss the considerations of therapeutic hypothermia for infants with mild HIE.

Join NAFI: www.nafinet.org For more information on Aerox Oxygen Systems and to learn more about their products see: www.aerox.com/ ------------------------------------------------------------------------------------------------------------ For this episode, we sit down with President and CEO of Aerox Oxygen Systems Scott Ashton to discuss common misconceptions of aviation oxygen, the history of the 12,500 O2 regulation, and why commercially available canned "shots" of oxygen can do more harm than good when used in the cockpit.  Just remember "It's Toxic to be Hypoxic"   About Aerox: From portable systems to highly engineered systems on Part 25 aircraft, Aerox® has a system for you to deliver high performance at an economical cost.   Since 1981 we have been providing the aviation industry with innovative solutions for all of its oxygen needs. While our comprehensive website is representative of many of the products that Aerox offers, if you don't see exactly what you are looking for, please contact us. Aerox is certified to ISO9001:2015 and AS9100D.  We offer a wide array of TSO oxygen masks and PMA oxygen cylinders in both Kevlar and Steel and operate FAA Repair Station YXQR567B We offer a complete line of stock or custom systems, parts, and accessories. We are a provider of OEM systems, serving Diamond, Agusta, Piper, and many others. We can also design any kind of emergency or portable system, for use in the air or on the ground. Contact us to let us know how we can help you. Aerox is family owned and operated by the Ashton Family.  CEO Scott Ashton is an aerospace engineer and an accomplished pilot with an Airline Transport Pilot Certificate.  He s rated in airplanes, gliders and helicopters.  He is also an active flight instructor and FAAST Team rep.  Scott was also President of the New England Air Museum and is a board member and volunteer pilot for PALS SkyHope.

Dr Glenn McConell chats with Professor Grégoire Millet from the University of Lausanne in Switzerland. He is an absolute world leader in research into altitude training and hypoxic conditioning. This area has progressed greatly from Live High-Train High (LHTH) to Live High-Train Low (LHTL), LLTH and LHTL (and High). The type of attitude training/hypoxic conditioning one would undertake depends on if training for endurance or team sports. We also discussed using low oxygen (hypoxia) and high oxygen (hyperoxia) for health benefits. 0:00. Introduction and Grégoire's background 4:58. History of altitude training 6:52. Many combinations of altitude training LHTH, Live High-Train Low (LHTL), LLTH, LHTL (and High) 9:45. Altitude and oxygen availability 12:45. Altitude vs breathing low oxygen: not the same 14:32. Immediate responses to hypoxia 20:12. Lower VO2 max at altitude 24:39. Absolute vs relative exercise intensity 25:46. Placebo effect? 28:45. Long-term responses to altitude 32:24. Need to exercise for optimal adaptations in muscle 33:34. LHTL 36:19. LLTH 41:34. Health effects of LLTH 43:04. Repeated sprints in hypoxia (RSH) 45:29. LLTH and improved blood vessel function 47:54. Health effects of low and high oxygen 54:50. Hypoventilation at low lung volume (VHL) to cause hypoxia 59:00. VO2 max training at altitude 1:00:55. Use more carbohydrate during exercise at altitude 1:02:30. Greater sympathetic activation (adrenaline etc) at altitude 1:04:52. Oxidative stress/ Reactive oxygen species 1:08:42. What doesn't kill you makes you stronger 1:10:12. Manipulating repeated sprints duration to alter aerobic/anaerobic contributions 1:13:20. Specificity of training to achieve required outcomes 1:13:51. LHTL (and High) in Rugby players 1:17:40. LHTL and LHTL (and High) for endurance 1:19:09. Ultramarathon star Killian Jornet and altitude training 1:21:15. Controversies in the area 1:24:47. Health benefits the most exciting for him 1:25:37. Outro (9 secs) Inside Exercise brings to you the who's who of exercise metabolism, exercise physiology and exercise's effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all. The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University. He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9). Connect with Inside Exercise and Glenn McConell at: Twitter: @Inside_exercise and @GlennMcConell1 Instagram: insideexercise Facebook: Glenn McConell LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460 ResearchGate: Glenn McConell Email: glenn.mcconell@gmail.com Subscribe to Inside exercise: Apple Podcasts: https://podcastsconnect.apple.com/my-podcasts/show/inside-exercise/03a07373-888a-472b-bf7e-a0ff155209b2 YouTube https://www.youtube.com/channel/UChQpsAQVEsizOxnWWGPKeag Spotify Google Podcasts Anchor Podcast Addict Etc

 Live High and Train Low? In this episode hosts Dr. Jinger Gottschall and Mac Cassin dive into the basics of altitude. The Definition, long-term and short-term responses, submaximal and maximum intensities. And then finally, a few strategies for training. From Sea Level to the Death Zone we help you understand Altitude in order to train and race effectively. Enjoy it! It's Nice! 

Guest: Betsy Pilon - In this episode, Michelle is joined by Betsy, the Executive Director of “Hope for Acquired Hypoxic Ischemic Encephalopathy (HIE).” This hour is a deeply profound conversation as one mom shares her journey of advocacy and empowerment, inspiring and educating us along the way. Join in as the topics of causes and current treatment for HIE. are presented. Potential long-term impacts and barriers to continued treatment after NICU discharge will be discussed.

Guest: Raquel Garcia, SLPD, CCC-SLP, CNT, BCS-S - In this course, the presenter discusses hypoxic-ischemic encephalopathy (HIE) and how this devastating diagnosis can result in pediatric dysphagia. We learn about new resources and organizations, such as “Hope for HIE”, that are educating and advocating interprofessional practice partners and caregivers about the most current research to advance the quality of care for even our littlest patients.

Do you struggle with knowing how to best breathe during CrossFit workouts? In this episode, learn how to breathe most efficiently in each movement & start crushing your MetCons. Listen with Show Notes: https://zoarfitness.com/podcast/055/Watch on YouTube: https://www.youtube.com/watch?v=S6JzwBEUen0Get Pro [Upgrade Your Fitness Knowledge]: https://zoarfitness.com/pro/The Protocol [Weekly Programming]: https://zoarfitness.com/theprotocol/1-on-1 Remote Coaching: https://www.zoarfitness.com/coach/Breath Work for the Sport of Fitness: https://www.zoarfitness.com/product/breath-work-for-crossfit/Gymnastics Density University: https://www.zoarfitness.com/product/gymnastics-density-university/Gymnastics Density for the Big Five: https://www.zoarfitness.com/product/gymnastics-density-for-crossfit/Bulletproof Body: Accessory Work for Functional Fitness: https://www.zoarfitness.com/product/bulletproof-body/Cyclical Supremacy: https://www.zoarfitness.com/product/cyclical-supremacy/Your First Muscle-Up: https://www.zoarfitness.com/product/your-first-muscle-up-program/Follow ZOAR Fitness on Instagram: https://www.instagram.com/zoarfitness/Support the show

References Dr Guerra's letures/reasoning SCIENCE ADVANCES • 22 May 2019 • Vol 5, Issue 5 Cell MetabolismVolume 22, Issue 2, 4 August 2015, Pages 304-311 Cell Chem Biol. 2020 May 21; 27(5): 538–550.e7. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

Matt Wyrick, who is in the sixth year of his FAA career, all at Indianapolis Center (ZID), grew up immersed in aviation. His father, Allan, was a longtime pilot for NetJets. Wyrick said hypoxia came up in some discussions between them. That, along with his training, prepared him to successfully assist the pilot of a Cessna 441 Conquest II who was exhibiting signs of hypoxia while over south-central Ohio en route to Youngstown, Ohio, at 29,000 feet. For his efforts, Wyrick has been named the Great Lakes Region winner of the 2021 Archie League Medal of Safety Award, presented by the National Air Traffic Controllers Association. He will be honored on June 17 in New Orleans. Wyrick said he was honored and humbled by the award. “I was just there doing my job that day and I had a bunch of good people around me who were a huge part of the outcome. I really think the award is more a reflection of everybody I work with. I don't have a doubt in my mind that any one of the controllers in my area could have sat there and achieved the same outcome.”

Like most critical aspects of health, stress can be a double-edged sword. It's necessary for physical and emotional growth, and we all know that what doesn't kill you makes you stronger. However, too much stress can do far more damage than even a poor diet or a sedentary lifestyle. The trick seems to be embracing the right kinds of stress in the right doses, and under those conditions, it can be a catalyst for improved strength and resilience. ​Today for the second instalment of our Health Fundamental series, NBT coaches Megan Hall and Clay Higgins are examining stress and hormesis. They talk about simple biomarkers to help you measure your current allostatic load and then they discuss simple, practical things anyone can do to better manage emotional stress. They also discuss how to use hormesis - intentional and measured amounts of stressors like temperature, exercise, diet, and breathing, to boost your body's functioning while becoming better adapted and stronger. To get all the details and studies supporting the information in this podcast, be sure to follow along with Megan's outline for this episode. Here's the outline of this episode with Megan Hall and Clay Higgins: [00:01:23] Defining stress: allostatic load, eustress, distress. [00:05:06] Dealing with negative stressors. [00:05:20] Sympathetic vs. parasympathetic. [00:05:49] Measuring allostatic load: Heart rate variability, resting heart rate, and other biomarkers. [00:06:41] Podcast: How to Know if You're Stressed, with Jason Moore. [00:07:26] Mike T. Nelson, PhD. [00:09:54] Simon Marshall, PhD.; Stress Audit (list of your problem-based and emotion-based coping strategies) - Podcast: How to Manage Stress. [00:11:16] Panoramic vision/optic flow as the basis for EMDR therapy; Podcast: How to Develop Coping Resilience and Mental Toughness. [00:13:05] Physiological sigh. [00:13:31] Spending time in nature; forest bathing (Shinrin-yoku). [00:14:35] Movement and exercise. [00:18:00] Breathwork; Podcast with James Nestor: How to Fix Your Breathing to Improve Your Health; Book: https://amzn.to/39wccpN. [00:19:55] Soma Breathwork; Podcast: How to Use SOMA Breathwork to Relieve Stress and Improve Your Health and Performance, with Nigel McHollan and Kara Lynn Kelly. [00:21:41] Nasal breathing vs. mouth breathing; inhale vs. exhale duration. [00:22:01] Circadian rhythm entrainment; DUTCH test; Doing a daily audit. [00:24:30] Q1 interventions (Quadrant 1 from the 4-Quadrant Model). [00:27:20] Podcast: Health Fundamentals: How to Get Great Sleep. [00:28:51] Previous podcasts on sleep: Why Sleep Is Critical for Immune Health (2/12/21); Better Sleep for Athletes (1/3/20); How to Use Cognitive Behavioral Therapy for Insomnia (12/13/19); What to Do When You Can't Sleep (11/22/19); Sleep To Win: How Navy SEALs and Other High Performers Stay on Top (10/25/19); Morning Larks and Night Owls: the Biology of Chronotypes (1/27/19); Why Your Diet Isn't Working: Sleep and Circadian Rhythm (9/3/18); How to Entrain Your Circadian Rhythm for Perfect Sleep and Metabolic Health (7/4/18); How to Get Perfect Sleep with Dr. Kirk Parsley, MD (4/15/16). [00:29:14] Simon Marshall's traffic light system; Podcast: How to Stay Consistent (Minute 11:00). [00:30:02] Community and social connection; Feeling lonely is associated with depression, anxiety, hopelessness, fatigue, poor life satisfaction. Finding a club, altruism. [00:33:06] Podcasts on community: The Compassion Project: The Power of Hope and Human Kindness (4/9/21), The Community Cure: Transforming Health Outcomes Together (11/13/20), Building Compassionate Communities to Improve Public Health (1/10/19). [00:33:26] Hormesis; Paper: Calabrese, Edward J., and Mark P. Mattson. "How does hormesis impact biology, toxicology, and medicine?." NPJ aging and mechanisms of disease 3.1 (2017): 1-8. [00:35:54] Review papers on Hormesis - find them in Megan's outline for this episode. [00:36:10] Temperature: extreme heat and cold. [00:37:16] Clay's DIY sauna. [00:38:50] Ben Lynch article on sauna: Sauna Benefits & How-To Guide, by Dr. Ben Lynch. [00:41:23] Exercise. [00:42:05] Lactate can improve cellular defense mechanisms; Study: Lactate and pyruvate promote oxidative stress resistance through hormetic ROS signaling. [00:42:50] Food as a hormetic stressor: manipulating macros. [00:44:46] Fasting and calorie restriction. [00:45:28] Fruit and vegetable compounds that stimulate detoxification; NRF2 stimulated by sulforaphane and resveratrol. [00:46:30] Hygiene hypothesis. [00:47:26] Oxygen stress; Altitude/hypoxia, LiveO2. [00:48:13] Getting a hormetic response from lower-intensity exercise; Study: Balestra, Costantino, et al. "Hypoxic and hyperoxic breathing as a complement to low-intensity physical exercise programs: A proof-of-principle study." International journal of molecular sciences 22.17 (2021): 9600. [00:49:06] Wim Hof Method. [00:50:15] Where to start. [00:50:43] Simon Marshall's podcasts on habit formation: Nudge Tactics for Performance and Health, How to Get Motivated. [00:53:22] More is not better - hormesis can have a cost. [00:55:14] Article: Defining Hormesis, by Calabrese and Baldwin.

For our 29th Podcast episode and to close out HIE Awareness month, I sat down with Brigid Janousek. She bravely shares the story of her son William's traumatic delivery and his subsequent treatment with therapeutic hypothermia due to his diagnosis of Hypoxic Ischemic Encephalopathy or HIE. Infants with HIE have experienced a lack of oxygen to the brain either prior to birth, during the birth process, after birth, or during childhood. Infants with suspected HIE are treated in the NICU with therapeutic hypothermia or cooling that needs to be initiated within the first 6 hours of life. The cooling therapy reduces the rate of brain cell death and the risk of reperfusion injury which commonly occurs due to the release of toxins from the injured brain cells. The cooling process occurs for 72 hours post-delivery and has been shown to minimize the extent of death and disability in children. Brigid shares a more in depth look into William's time in the NICU, and how they first learned about his diagnosis. She explains why they felt like they were outcasts in the NICU due to William being a term infant. Brigid shares the struggles they endured once they were discharged home and how she unknowingly was suffering from postpartum depression, perinatal mood disorder, and PTSD. We discuss ways it was helpful for her to work through her trauma and why she is so passionate about bringing awareness to the misconception that all NICU babies are preterm as well as the importance of focusing on maternal mental health. We thank Brigid for sharing her family's very personal story. It is our goal to help bring awareness to HIE and to help break down some of the barriers and social disparities that exist with HIE infants and full-term NICU babies and strive for inclusive NICU messaging.Stay tuned, you will not want to miss their story…Our NICU Roadmap: https://empoweringnicuparents.com/nicujournal/Website: https://empoweringnicuparents.comEmpowering NICU Parents Show Notes: https://empoweringnicuparents.com/episode29/Empowering NICU Parents Instagram: https://www.instagram.com/empoweringnicuparents/Empowering NICU Parents FB Group: https://www.facebook.com/groups/empoweringnicuparentsPinterest Page: https://pin.it/36MJjmH

Omicron update, COVID stats, assessment of the hypoxic COVID patient Reference: Dhont, S., Derom, E., Van Braeckel, E. et al. The pathophysiology of ‘happy' hypoxemia in COVID-19. Respir Res 21, 198 (2020). https://doi.org/10.1186/s12931-020-01462-5

My interview with the band discussing their album A New Way Of Death and much more! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/robert-carrigan/support

To honor HIE Awareness Month this April, I sat down with the Executive Director for Hope for HIE, Betsy Pilon. Betsy shares her personal experience after her son, Max was diagnosed with HIE or Hypoxic Ischemic Encephalopathy, a type of neonatal brain injury. Listen to hear how repetitive gaps in resources and lack of support for HIE families drove her to make a change. She now spearheads the non-profit organization to help other HIE families navigate their journey. By promoting awareness, education, and support, she ensures that no one feels alone after a diagnosis of HIE. Despite permanent impacts from Max's HIE, he is living his best life, thriving in school, and optimizing the opportunities given to him. They have learned through their personal journey and the support of the HIE community that families and individuals can thrive in their own ways. Empowering NICU Parents Show Notes:https://empoweringnicuparents.com/episode9/Empowering NICU Parents Instagram: https://www.instagram.com/empoweringnicuparents/Empowering NICU Parents FB Group:https://www.facebook.com/groups/empoweringnicuparents

In this episode's off-topic section, Josh talks about that time he saved a skydiver that was unconscious in freefall due to hypoxia. The story and accompanying video is one hell of a dizzying event, literally and figuratively. Brett then rants about one critic named Nick who was just trying to go about his job of criticizing books and stuff. Oh yeah, Brett also talks about the debut novel from Ernest Cline: Ready Player One. Did someone order the dystopian sci-fi with a side of utopian Oasis?   Off-top Links and References: Hypoxic Skydive Video Have Not Seen This Podcast   Content: Ready Player One (Book) Oasis Beta Launches on Oculus Rift Ernest Cline Visits Oculus HQ Grumpy Nick's Review   Follow Us: All of our links! Facebook Instagram Sponsor: Best Maps Ever

This episode covers hypoxic-ischaemic encephalopathy.Written notes can be found at https://zerotofinals.com/paediatrics/neonatology/hie/ or in the neonatology section in the Zero to Finals paediatrics book.The audio in the episode was expertly edited by Harry Watchman.

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