Podcasts about lipids

Discover why cotton candy can beat a corn dog, how the perimeter-of-the-store hack simplifies everything, and what it really looks like to eat like your great-grandparents. Episode Summary In part 3 of the “Ancestral Mismatch” series, Ben Greenfield delivers three no-nonsense dietary strategies that anyone can implement without breaking the bank or setting foot in an overpriced health food store. You'll learn why fried seed oils are more damaging than sugar (and why Ben would choose cotton candy over a corn dog every time), how to avoid ultra-processed foods by shopping the perimeter of any grocery store, and why sourcing your food matters for your health, animal welfare, and the planet. Ben even drops his go-to travel grocery list that works at any supermarket on Earth. Question of the Day

Autism, Parenting, And The Art Of Ignoring Unsolicited Advice Julie Green had a very limited understanding of autism before her son was born. Navigating his diagnosis was difficult, especially when differing opinions were being thrown at them from all sides. Green reveals the realities of motherhood, autism, and self-discovery in her new book, Motherness. Guests: Julie M. Green, author, Motherness Host: Elizabeth Westfield Producer: Kristen Farrah     Kitchen Chemistry: The Cooking Oil That May Be Driving Obesity Though there are various cooking oils to choose from, soybean oil remains the most commercially popular choice in America. But is this cheap option making us obese? Our experts reveal how the high concentration of a particular fatty acid in this common oil may be influencing how our bodies store fat and contribute to rising health concerns. Guests:  Sonia P. Deol, assistant professional researcher in the department of microbiology and plant pathology, University of California, Riverside Frances M. Sladek, professor of cell biology & toxicologist, University of California, Riverside Host: Greg Johnson Producer:  Kristen Farrah   Medical Notes: How Energy Drinks May Worsen Your Cancer, A Non-Invasive Treatment For Seizures, And How To Fight Against Procrastination   Are energy drinks making you sick? A new treatment for seizures may soon be possible without the need for invasive brain surgery. Good news for sugar addicts! Scientists have created a healthier sweetener using tagatose. How to fight against procrastination. Host: Maayan Voss de Bettancourt Producer: Kristen Farrah Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Kitchen Chemistry: The Cooking Oil That May Be Driving ObesityThough there are various cooking oils to choose from, soybean oil remains the most commercially popular choice in America. But is this cheap option making us obese? Our experts reveal how the high concentration of a particular fatty acid in this common oil may be influencing how our bodies store fat and contribute to rising health concerns.Guests: Sonia P. Deol, assistant professional researcher in the department of microbiology and plant pathology, University of California, RiversideFrances M. Sladek, professor of cell biology & toxicologist, University of California, RiversideHost: Greg JohnsonProducers: Kristen Farrah Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Key TakeawaysHow does the precise localization of GPCRs in lipid rafts reshape drug discovery strategy? Examine implications for functional assays and therapeutic innovation.Explore the pivotal role of GPCR-lipid raft compartmentalization in receptor signaling, desensitization, and pharmacology research. Dr. Keyvan Sedaghat discusses assay approaches, regulatory mechanisms, and the translational impact of bitter taste receptors beyond sensory biology. Leveraging decades of experience in assay development and database creation, he offers actionable insights for researchers optimizing GPCR drug discovery pipelines.Compartmentalization of GPCRs in lipid rafts directly influences receptor signaling and drug response.Desensitization pathways of dopamine D1 receptors depend on precise phosphorylation domains—challenging classical paradigms.Bitter taste receptors demonstrate functional relevance in non-gustatory tissues with emerging therapeutic applications.Database-driven research accelerates the identification of receptor-microdomain interactions for novel targets.Integration of computational modeling and biochemical validation is essential for advancing GPCR assay strategies.Dr. GPCR Links & ResourcesAccess the Dr. GPCR Ecosystem at https://www.ecosystem.drgpcr.com/ for community, tools, and databases.Details on Membership & Pricing: https://www.ecosystem.drgpcr.com/university-pricingGPCR Weekly News: https://www.ecosystem.drgpcr.com/gpcr-weekly-newsExplore Dr. GPCR Premium for expanded translational resources and networking.About the GuestDr. Keyvan Sedaghat holds a pharmacy degree and a PhD in cellular and molecular medicine, specializing in pharmacology, from the University of Ottawa. With over two decades of academic experience, he has served as a professor, senior lecturer, and chief scientific officer in the pharmaceutical and cosmetic industries. Dr. Sedaghat's work spans peer-reviewed publications and editorial roles across journals in molecular pharmacology, cell signaling, and G protein-coupled receptors. His scientific drive centers on unraveling molecular mechanisms underlying GPCR function and translating those findings into effective teaching, research, and drug discovery strategies.Guest on the Web:LinkedInGoogle Scholar

Today, I am excited to share the first class in a series of lipid masterclasses with the amazing Dr. Thomas Dayspring! Dr. Dayspring is certified in internal medicine and clinical epidemiology and is a fellow of the American College of Physicians and the National Lipid Association. He was previously the Educational Director of a nonprofit organization and has served as the Chief Academic Advisor for two major cardiovascular labs.  Given the in-depth nature of my discussions with Dr. Dayspring over several sessions, each lasting nearly six hours, it seemed logical to present these masterclasses in segments to make them easier to understand. In our first class today, we dive into the fundamentals, exploring what lipids are and how lipids and fatty acids are classified. We cover the physiology and transport of cholesterol and the roles of apoptosis, apo-proteins, and apo-lipoproteins; we unravel the differences between HDL, LDL, IDL, and VLDL; and we explain how to calculate LDL and triglycerides to assess metabolic health. Dr. Dayspring also shares his preferences regarding lab values and indicators that help him assess the early risk of cardiovascular disease. We cover some detailed aspects of physical chemistry in this episode, so I highlight the main clinical points throughout our conversation to make it easier to follow. Be sure to join Dr. Dayspring and me for our next episode in the lipid masterclass series. IN THIS EPISODE YOU WILL LEARN: What are lipids, and why are they important? Dr. Dayspring explains what triglycerides are. How lipids get absorbed and transported throughout the body What lipoproteins are, and how they get classified How cholesterols get calculated The impact of triglycerides on cholesterol levels and cardiovascular health How high triglyceride levels can indicate early insulin resistance or increased ASCVD risk What is the role of HDL particles? How metabolic syndrome impacts cardiovascular health Bio: Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, he moved to Virginia in 2012. He served as an educational director for a nonprofit cardiovascular foundation and, until mid-2019, as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular / lipidology educator. Career-wise he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women's cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He was the recipient of the 2011 National Lipid Association's Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association and serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Thomas Dayspring ⁠Twitter⁠ (@DrLipid) ⁠LinkedIn⁠ ⁠Books written by Gary Taubes⁠ 

Contributor: Alec Coston, MD Educational Pearls: Disclaimer: this has nothing to do with the ER but is too cool to not talk about. Condition: Carbamoyl phosphate synthetase 1 (CPS1) deficiency Rare inborn error of metabolism Inability to properly break down ammonia Leads to severe hyperammonemia and hepatic encephalopathy Natural history: Without treatment, typically fatal within the first few weeks of life Even with current standard treatments, life expectancy is often limited to ~5–6 years Breakthrough treatment: A team of researchers at the Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania developed the CRISPR-based targeted gene therapy for this patient. First-of-its-kind precision approach tailored to the patient's specific mutation Key components of the therapy: Whole-genome sequencing to identify the exact CPS1 mutation Creation of a custom base-editing enzyme designed to correct that specific mutation Design of a guide RNA to direct the base editor to the precise genomic location Delivery method: Lipid nanoparticles used to deliver the gene-editing machinery Nanoparticles can be targeted to specific tissues Why the liver works well: CPS1 is primarily expressed in hepatocytes The liver is relatively easy to target with lipid nanoparticles Hepatocytes divide frequently, allowing edited genes to be passed on as cells replicate Long-term impact: Once edited, cells continue producing functional CPS1 enzyme Potential for durable, possibly lifelong correction from a single treatment References https://www.nih.gov/news-events/news-releases/infant-rare-incurable-disease-first-successfully-receive-personalized-gene-therapy-treatment Choi Y, Oh A, Lee Y, Kim GH, Choi JH, Yoo HW, Lee BH. Unfavorable clinical outcomes in patients with carbamoyl phosphate synthetase 1 deficiency. Clin Chim Acta. 2022 Feb 1;526:55-61. doi: 10.1016/j.cca.2021.11.029. Epub 2021 Dec 29. PMID: 34973183. Bharti N, Modi U, Bhatia D, Solanki R. Engineering delivery platforms for CRISPR-Cas and their applications in healthcare, agriculture and beyond. Nanoscale Adv. 2026 Jan 5. doi: 10.1039/d5na00535c. Epub ahead of print. PMID: 41640466; PMCID: PMC12865601. Summarized and edited by Jeffrey Olson MS4 Donate: https://emergencymedicalminute.org/donate/ Join our mailing list: http://eepurl.com/c9ouHf

Artificial intelligence is rapidly changing how we understand our health — not just how we feel today, but how fast we're actually aging.On this episode of Live Long, host Peter Bowes continues his personal experiment with Hundred, the AI-powered longevity platform that combines advanced blood testing, wearable data and personalized insights to track biological age and guide smarter health decisions.After introducing the app in an earlier conversation, Peter reconnects with Hundred's founder, Tyler Smith, to go deeper into the idea of a “health operating system” — essentially a personal doctor in your pocket. Together they explore how continuous testing and AI analysis could help prevent disease, spot risks earlier, and motivate lasting behavior change — while also addressing the realities of over-testing, false alarms, privacy concerns and health anxiety.Peter also shares the results of his own first round of testing, what surprised him most, and how he's using the data to shape his approach to longevity and healthy aging.-----JOIN HUNDREDOptimize your healthspan and potentially lower your biological age.  Tyler and the team at HUNDRED are offering $75 in credit for add-on tests and supplements from the HUNDRED marketplace when you sign up at hundred.com/livelongpodcastThis podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/Time-line Mitopure (a highly pure form of Urolithin A) boosts the health of our mitochondria – the battery packs of our cells – and improves muscle strength. Time-line is offering LLAMA listeners a 10% discount on its range of products – Mitopure powders, softgels & skin creams.  Use the code LLAMA at checkout-Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts SpotifyEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountPartiQlar supplementsEnhance your wellness journey with pure single ingredients. 15% DISCOUNT - use code: MASTERAGING15Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Sorry for the hiatus but we are back with a new episode on a topic that everyone can relate to! In this episode, we speak to Dr. Elliot Lass about lipids and everything related to managing lipids as a family physician whether it is using laboratory results or making decisions on lifestyle changes. Drawing from his personal experience, Elliot gives us insight into the importance of balancing risk versus benefits when taking care of patients across all ages, even for routine medical issues like lipids.

We have another short-form, live YouTube episode today, where I dive into questions from listeners. Recently, the most frequently asked questions have been about cholesterol, likely because I often reference my podcast series with Dr. Tom Dayspring, a renowned lipidologist and menopause expert. Join me today to clear away some more of the confusion surrounding cholesterol. IN THIS EPISODE, YOU WILL LEARN: Why comprehensive lipid testing rather than standard testing is essential, post-menopause How menopause impacts women's lipid and triglyceride levels The roles APO B and Lp(a) play in assessing cardiac risk How the cardiac risk of women increases as estrogen declines The cardiac health benefits of monitoring lipids and considering HRT within the first six years of menopause What research studies reveal about how menopause influences cardiovascular risk Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Episodes with Dr. Thomas Dayspring: Episode 336: Lipid Masterclass: An Introduction to Lipids and Cholesterol with Dr. Thomas Dayspring Episode 344: Lipid Masterclass: A Deep Dive into Our Cardiovascular Needs with Thomas Dayspring Episode 352: Lipid Masterclass: Apo-B, Labs and Women's Heart Health with Thomas Dayspring Episode 495: Are You At Risk for Dementia? – The Most Overlooked Cholesterol Marker You Need to Know with Dr. Thomas Dayspring

Dr. Jessica Rose, PhD, MSc, BSc, is a Senior Fellow specializing in Computational Biology from Canada. She holds a Bachelor's Degree in applied mathematics and a master's degree in Immunology from Memorial University of Newfoundland, and a PhD in Computational Biology from Bar Ilan University. Dr. Rose has completed two post-doctoral degrees in Molecular Biology from the Hebrew University of Jerusalem, and in Biochemistry from the Technion Institute of Technology. She is best known for her contributions to public health and safety related to the COVID-19 injectable products, and her analyses of pharmacovigilance databases like VAERS. In this episode, Drs. Brian and Jessica talk about… (00:00) Intro (04:57) Dr. Jessica's upbringing, personality, and scientific pursuits (09:41) Covid vaccines, natural immunity, and bodily autonomy of individuals (19:50) The research of Kevin McKernan on DNA in vials of COVID-19 vaccines (27:39) The composition and production of Covid mRNA vaccines (33:04) National health regulation agencies and Covid vaccine DNA contamination (35:54) Lipid nanoparticles in mRNA vaccines and how they impact human health (44:22) Vaccine injuries due to spike protein proliferation and how the spike protein ruins the human immune system (54:38) Spike protein detox therapies (01:01:12) Fascia release (01:03:07) Cholesterol, gal bladder health, and nutrition (01:07:54) Fasting, autophogy, and the microbiome (01:11:33) Peer review and post-peer review attacks on valid research (01:21:53) Outro   For more information, please see the links below. Thank you for listening!   Links:   Resources Mentioned in this Episode: Jules Horn (Fascia Release): https://www.youtube.com/@Jules_horn Science Guardians (post-peer review group): https://x.com/SciGuardians   Dr. Jessica Rose: Research: https://www.researchgate.net/profile/Jessica-Rose-24 Why does DNA remain in vials of COVID-19 mRNA Shots?: https://rumble.com/v74rdvs-why-does-dna-remain-in-vials-of-covid-19-mrna-shots.html What Jessica Rose Knows: Dr. Jessica Rose on DarkHorse: https://rumble.com/v5q0zl8-what-jessica-rose-knows-dr.-jessica-rose-on-darkhorse.html   Dr. Brian Lenzkes:  Arizona Metabolic Health: https://arizonametabolichealth.com/ Low Carb MD Podcast: https://www.lowcarbmd.com/   HLTH Code: HLTH Code Promo Code: METHEALTH • • HLTH Code Website: https://gethlth.com

BUFFALO, NY — January 15, 2026 — A new #research paper was #published in Volume 17, Issue 12 of Aging-US on December 1, 2025, titled “CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice.” Led by Taesik Gwag and Shuxia Wang from the University of Kentucky and the Lexington Veterans Affairs Medical Center, the research shows that reducing CD47 levels improves blood sugar regulation and lipid balance in older mice. These findings are significant because metabolic disorders linked to aging increase the risk of diabetes, cardiovascular disease, and other chronic conditions. The results suggest that CD47 may be a promising target for improving metabolic health during aging. As people age, metabolic problems such as insulin resistance, high cholesterol, and increased abdominal fat become more common, even without significant weight gain. CD47 is known to play roles in immune signaling and aging-related inflammation, and earlier studies have linked it to metabolic dysfunction. This study examined whether lowering CD47 activity could reverse age-related metabolic decline. Researchers treated aged male mice with an antisense oligonucleotide (ASO) designed to reduce CD47 for ten weeks. The treatment led to lower fasting blood glucose, improved glucose tolerance, and enhanced insulin sensitivity. Circulating lipid levels, including cholesterol and free fatty acids, were also reduced. Importantly, these benefits occurred without changes in overall body weight, indicating improved metabolic efficiency rather than weight loss. “Twenty-month-old male mice were treated with control ASO or CD47 ASO (25 μg/g) for 10 weeks.” One of the most notable findings was a selective reduction in visceral fat, the deep abdominal fat closely associated with metabolic disease. Fat cells in this tissue were smaller, reflecting reduced fat production within the cells rather than increased fat breakdown. This change helps explain why metabolic health improved without weight loss. Treatment also improved brown fat tissue function. Brown fat plays a key role in energy use and metabolism. Treated mice showed increased activity of genes involved in energy burning and hormone-like signaling, supporting improved whole-body glucose and lipid balance. Moreover, the liver showed improved glucose metabolism. While liver fat content was unchanged, genes involved in glucose uptake and processing were more active, further contributing to better blood sugar control. Together, these findings identify CD47 as a key regulator of age-related metabolic dysfunction. By improving glucose control, lipid balance, and fat tissue function in aged male mice, CD47 antisense therapy offers a promising path for future strategies aimed at reducing metabolic disease risk in aging populations. DOI: https://doi.org/10.18632/aging.206343 Corresponding authors: Taesik Gwag - Taesik.gwag@uky.edu and Shuxia Wang - swang7@uky.edu Abstract video: https://www.youtube.com/watch?v=U6CiiOIaIWI Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206343 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Hello everyone! We are delighted to be back in studio for a staggering-to-us ninth season of 2 Dudes Doin' Trivia! As always, thanks to all the long time listeners, and welcome to the new ones :)Season 9 once again features our classic game type: This or That. We present each other two sets of clues and we pick "this category" or "that category" to play this episode, and defer the other category to a future episode. We do that twice for four total sets! We and the listeners really enjoy this game!But that's not all! We introduce a new segment in Season 9, with the abbreviated name TMITSSTATOPWFI, and we hope at least one listener finds this new segment interesting :)Listen in and play along with us for Season 9 Episode 1's categories, which are Burgers; Questions Written for [Will's] Mom; Short; and the succinctly named Things That Simpsons Fans Will Know Easily And Right Away, But Non-Simpsons Fans Have A Way Into The Answer.You know our coordinates by now, so drop us a line if you like :). See you in two weeks!

Send us a textDr. Christie M. Ballantyne, MD is a Cardiologist and is one of the nation's foremost experts on lipids, atherosclerosis and heart disease prevention. He holds many leadership positions at Baylor College of Medicine ( https://www.bcm.edu/people-search/christie-ballantyne-17846 ), including director of the Center for Cardiometabolic Disease Prevention, co-director of the Lipid Metabolism and Atherosclerosis Clinic, and chief of the Section of Cardiology. With over 1000 publications in the area of atherosclerosis, lipids, and inflammation, Dr. Ballantyne's research on heart disease prevention has led him to become an established investigator for the American Heart Association and the recipient of continuous funding from the National Institutes of Health with a core focus on in basic research of leukocyte–endothelial interactions, translational research in biomarkers, and clinical trials.Dr. Ballantyne's many accomplishments have included being elected as Fellow of the American Association for the Advancement of Science, the American Society of Clinical Investigation, and the Association of American Physicians. In 2012, he received the American College of Cardiology Distinguished Scientist Award (Basic Domain). In 2014 and 2015, Thomson Reuters recognized Dr. Ballantyne as one of “The World's Most Influential Scientific Minds.” Clarivate Analytics, Web of Science, named Dr. Ballantyne as a “Highly Cited Researcher” 2017-2022 in the top 1% of researchers most cited. In 2019, Dr. Ballantyne was awarded the Baylor College of Medicine Michael E. DeBakey, M.D., Excellence in Research Award. His research in biomarkers has led to the FDA approval of 2 biomarkers for cardiovascular risk prediction, and he has played a prominent role in the development and FDA approval of new therapies for treatment of lipids.Dr. Ballantyne also serves on the Editorial Board for Circulation and the Journal of the American College of Cardiology. He received his MD from Baylor College of Medicine with internal medicine residency at The University of Texas Southwestern Medical School and cardiology fellowship at Baylor College of Medicine and an AHA fellowship at the Howard Hughes Medical Institute and Institute for Molecular Genetics at Baylor.Dr. Alexander Tal, MD is an accomplished and recently retired board-certified Endocrinologist ( https://www.doximity.com/pub/alexander-tal-md ) with extensive training from institutions like Baylor College of Medicine, East Tennessee State University/Quillen College of Medicine, Mount Sinai Hospital Medical Center of Chicago and Tel Aviv University Sackler, where he specialized in Diabetes, Metabolism, and Geriatric Medicine, and held Fellow status with the American Association of Clinical Endocrinology, treating various hormonal conditions.Important Episode Link - Merck's Enlicitide Decanoate, an Investigational Oral PCSK9 Inhibitor, Significantly Reduced LDL-C in Phase 3 CORALreef Lipids Trial - https://www.merck.com/news/mercks-enlicitide-decanoate-an-investigational-oral-pcsk9-inhibitor-significantly-reduced-ldl-c-in-phase-3-coralreef-lipids-trial/#ChristieBallantyne #Cardiologist #Lipids #Atherosclerosis #HeartDiseasePrevention #BaylorCollegeOfMedicine #CardiometabolicDisease #LipidMetabolism #Cardiology #AlexanderTal #Endocrinologist #Diabetes #Metabolism #GeriatricMedicine #Merck #Enlicitide #OralPCSK9Inhibitor #Statins #Ezetimibe #Hypercholesterolemia #apoB #Lpa #Lipoproteins #Healthspan #Longevity #Aging #STEM #Innovation #Science #Technology #Research #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #Podcasting #ViralPodcastSupport the show

Ever wonder why your skin changes so much in winter? In this episode of Biohacking Beauty, we explain what actually happens when humidity drops, TEWL rises and indoor heating pulls moisture from the skin. We also talk about UVA exposure in cold months, lifestyle shifts that increase oxidative stress and why winter puts more pressure on your skin's repair systems.We break down the winter ingredients that matter most, like ceramides, barrier lipids, vitamin F, beta glucan, hyaluronic acid, peptides, NAD precursors and exosomes, and how to use them in a routine that supports barrier strength and cellular energy. We also share simple protocol adjustments for different climates and biological skin ages.If you want a clear strategy for keeping your skin healthy and supported through the colder months, this episode gives you everything you need.What's Discussed:(00:36) How Winter Alters Skin Biology and Accelerates Aging(03:01) TEWL and Barrier Breakdown: Why Skin Gets Drier and More Reactive(06:26) The Hidden Winter Risk: UVA, Snow Reflection and Daily SPF Needs(12:47) Glycation, Inflammaging and NAD Decline During Winter(15:18) Essential Winter Ingredients: Ceramides, Lipids, Vitamin F and Smart Hydration(21:43) Longevity Actives: NAD Precursors, Peptides, Exosomes and Mitochondrial Support(28:11) Building the Winter Routine: Climate Adjustments and Repair Protocols(37:41) Tiered Protocols for Every Age: 30s, 40s, 50s and BeyondLinks Mentioned in This Episode: Watch our Instagram Reel on Red Light Therapy here!You can find Young Goose's Winter Protocol here!Find more from Young Goose:VAMPIRE EXOSOMES: Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com Instagram: @young_goose_skincare

A breakthrough in inflammatory support has arrived in the natural health market. PEA, which stands for palmitoylethanolamide, is a naturally occurring fatty acid derivative made in the body and found in small amounts in foods. Several human studies have demonstrated that PEA has broad- spectrum pain-relieving properties, anti-inflammatory effects, and nerve protection.To help us unpack all the research and studies we have Dr. Stengler joining us today.In addition to authoring 30 books on health and several best-sellers such as “The Natural Physician's Healing Therapies,” “Prescription for Natural Cures,” “Prescription for Drug Alternatives,” and “Outside the Box Cancer Therapies,” Dr. Stengler has been published in several peer-reviewed medical journals such as The International Journal of Family & Community Medicine, Endocrinology & Metabolism International Journal, and Journal of Nutritional Health & Food Engineering.Dr. Stengler's, NMD. The newest book is called, The Holistic Guide to Gut Health. A comprehensive yet accessible approach to healing leaky gut and the many uncomfortable symptoms it causes. Dr Stengler is also the founder of The Stengler Center for Integrative Medicine.Talking Points:Palmitoylethanolamide (PEA), is a naturally occurring fatty acid derivative made in the body and found in small amounts in foods. PEA was first discovered in 1957 by scientists at Merck Sharp & Dohme, who isolated it from egg yolk, peanut meal, and soy lecithin. They found that PEA had anti-inflammatory properties in guinea pigs.However, PEA's role as a potential therapeutic agent was not widely recognized until 1993, when Rita Levi-Montalcini and her colleagues published research that suggested PEA has anti-inflammatory properties. Levi-Montalcini's group termed PEA an autocoid local injury antagonist (ALIA), and suggested that it acts locally to counteract injury.Multiple studies have demonstrated that PEA improves all sorts of pain. For example, a 2023 analysis of 11 studies found that PEA improved pain of various conditions, including muscle and joints, nerves, gynecological, and digestive. In terms of joint pain, a high-quality study demonstrated that PEA significantly reduced adult joint pain compared to placebo. Moreover, 8 clinical trials demonstrated that PEA was effective for low back pain, sciatica, and carpal tunnel syndrome. Even migraine headache pain was shown in published research to be improved with PEA.Lipid mediators help to balance the immune, nervous, and endocrine systems, affecting pain pathways related to inflammation. But unfortunately, due to changing diets, many of us do not get the nutrition and activity we need to make enough PEA ourselves.Supplemental PEA, by Levagen+ is properly formulated for optimal bioavailability, 75% more bioavailable to cell receptors than dietary forms. Levagen+ liposomal delivery of PEA has been clinically studied and shows benefits in joint pain, nerve pain, migraine, infections, sleep, and cognitive function.Learn more about Dr. Mark Stengler, NMDLearn more about Emerald Labs PEA+ Levagen Use the code: Forever and get 20% off your order.

Microbes are awesome, says biologist Paula Welander. They have shaped Earth's chemistry and its environment over billions of years, including oxygenating the planet to make it habitable for larger life forms. In turn, microbes have been shaped by that very same environment, evolving as the climate has evolved, she says. Welander now studies the lipid membranes of ancient microbes, which can endure for millions of years, to understand this evolution and where we might be headed in the future. Microbes are our connection to the ancient world, Welander tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: ​​Paula V. WelanderConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Paula Welander, a professor of Earth Science at Stanford University.(00:04:06) Why Study Microbial LipidsWhy lipids are essential for modern microbiology and Earth's history.(00:05:19) Diversity of Microbial MembranesHow bacteria and Archaea build different kinds of membranes.(00:07:15) Reconstructing Ancient EnvironmentsUsing specific lipid biomarkers to understand the early planet.(00:09:20) Chemical Fossils vs. Organism FossilsWhy microbes don't leave traditional fossils—but their lipids do.(00:10:55) Lipids as Environmental CluesHow certain lipids indicate the environments organisms lived in.(00:12:36) Archaea: A Distinct and Ancient EntityArchaea's evolutionary importance and chemically distinct membranes.(00:15:43) The Lipid DivideWhy eukaryotic membranes resemble bacterial, not Archaeal, membranes.(00:17:12) Tracing Membrane EvolutionRecent breakthroughs in studying Archaeal lineages related to eukaryotes.(00:19:11)  Lipid Preservation Over TimeHow archaeal lipids are especially reliable as long-term biomarkers.(00:20:58) Sterols as BiomarkersThe role sterols, including cholesterol, play in lipid archeology.(00:23:14) Bacterial Cholesterol DiscoveryThe discovery that a rare bacteria can synthesize sterol precursors.(00:25:02) Functional Roles of Bacterial SterolsThe possible roles sterols may play in microbial membranes and cell function.(00:26:31) Archaea in the Human GutThe number and types of Archaea found in the human microbiome.(00:28:43) Archaea and AntibioticsWhether Archaea react similarly to bacteria when exposed to antibiotics.(00:29:46) Future In a MinuteRapid-fire Q&A: hope, research needs, and alternate career dreams.(00:31:43) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Send Audrey a Text to get your question answered on the showWhether it is a new "forage feed" for your horses or the same old tired concentrated feed products, you will find Vitamin E on the label. Today, we are talking about why that doesn't count towards your horse's daily vitamin E requirement and what to do instead.References Nielsen M M et al. (2022). Lipid oxidation in whole-grain flour during storage after milling. University of Copenhagen.Barden L & Decker E A (2016). Lipid Oxidation in Low-Moisture Foods: Mechanisms and Role of Antioxidants. Critical Reviews in Food Science and Nutrition.Merck Veterinary Manual. Vitamin E in Horses — Nutrition and Feed Management.Liu Q et al. (2020). Effect of fat supplementation and vitamin E on oxidative status in exercising horses. Journal of Animal Science.Barden L et al. (2015). Tocopherols as natural antioxidants in cereal products. Journal of Cereal Science. Find all the Resource Listed Here: linktr.ee/equineenergymed Audrey is not an MD or DVM and has never implied or claimed to be either. Audrey holds a Doctoral Degree of Traditional Naturopathy and a Masters Degree in Science. She created an evidenced-based anti-inflammatory nutrition program for equine and has successfully helped over 10k horses. This information is not meant to diagnose, prescribe for, treat, or cure, and is not a replacement for your veterinarian. These are my personal interpretations based on my education, skill and clinical experience.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Sarah Cogle, PharmD, BCNSP, FASPEN Evolving evidence supports the shift from single-source to multi-source intravenous lipid emulsions in parenteral nutrition. These newer formulations may offer improved metabolic, inflammatory, and hepatic outcomes, particularly for vulnerable patient populations. Joining Dr. Charles Turck to discuss the clinical rationale and operational considerations for these formulations is Dr. Sarah Cogle, who's a Clinical Pharmacist Specialist at Vanderbilt University Medical Center in Nashville, Tennessee.

In this episode of The Brainstorm, we delve into the groundbreaking advancements in gene editing, focusing on its potential to transform healthcare. We explore the shift from treating rare diseases to tackling common killers like cardiovascular disease, and discover how CRISPR technology is paving the way for a new era in medical treatment.If you know ARK, then you probably know about our long-term research projections, like estimating where we will be 5-10 years from now! But just because we are long-term investors, doesn't mean we don't have strong views and opinions on breaking news. In fact, we discuss and debate this every day. So now we're sharing some of these internal discussions with you in our new video series, “The Brainstorm”, a co-production from ARK and Wolf.financial, and sponsored by Public. Tune in every week as we react to the latest in innovation. Here and there we'll be joined by special guests, but ultimately this is our chance to join the conversation and share ARK's quick takes on what's going on in tech today.Key Points From This Episode:CRISPR-based gene editing is moving from treating rare diseases to addressing common conditions like cardiovascular disease.The transition from ex vivo to in vivo gene editing could simplify treatment processes significantly.Lipid nanoparticle delivery is a key advancement enabling in vivo gene editing.The potential market for in vivo gene editing treatments is vast, with significant implications for healthcare costs and patient outcomes.To learn more about WOLF: https://wolf.financialTo learn more about Public: https://public.com/Relevant Links:https://www.ark-invest.com/newsletters/issue-491

Could a decline in "plasmalogens" be a missing link in Alzheimer's and aging? Dr. Peter Meikle reveals why this critical brain lipid drops as we age and the surprising foods that might help restore it.In this interview, we sit down with Dr. Peter Meikle, Head of the Metabolomics Laboratory at the Baker Heart and Diabetes Institute, to explore the critical role of plasmalogens in human health. Plasmalogens are unique phospholipids that act as powerful antioxidants, protecting our cell membranes from oxidative stress. Dr. Meikle explains how plasmalogen levels naturally decline with age and why this drop is strongly associated with Alzheimer's disease, heart disease, and fatty liver.We dive deep into the genetic connection, specifically how the ApoE4 gene impacts these lipids, and discuss the results of mediation analyses that suggest a causal link to neurodegeneration. Finally, Dr. Meikle shares practical advice on how to boost your levels, debating the trade-offs of dietary sources like eggs and red meat versus supplements like krill oil and shark liver oil, and outlines the future of synthetic plasmalogen therapy.

Susan Schwab talks about how she got the research bug, bugs she ate, and her research on how the lipid S1P helps T cells decide- should I stay or should I go. Host: Cindy Leifer Guest: Susan Schwab Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Schwab lab website Monocytes produce the lipid S1P to regulate T cell movement Review on S1P and immune cell migration Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Master cardiovascular disease prevention! Learn how to apply the new PREVENT risk calculator, use the CPR framework for risk reclassification, and interpret ApoB and Lp(a) in modern lipid management. We're joined by Dr. Laurence Sperling to break down what's new in ASCVD risk assessment and prevention. Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments Intro Case 1 from Kashlak  Risk assessment framework ApoB and Non-HDL cholesterol Lipoprotein(a) and its importance The PREVENT risk score and its implications Statins and other lipid lowering therapies The role of diet and lifestyle in lipid management Case 2 from Kashlak Familial Hypercholesterolemia diagnosis and management Key takeaways Outro Credits Producer, Writer, Shownotes, Infographic, and Cover art: Ben Furman, MPH  Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Leah Witt, MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Laurence Sperling, MD  Disclosures Dr. Sperling reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. Sponsor: Bucksbaum-Siegler Institute If you want to learn more about what the Bucksbaum-Siegler Institute is doing and to nominate someone for the Clinical Excellence Award—you can check them out today. Visit bucksbauminstitute.uchicago.edu. Sponsor: Grammarly  Sign up for FREE and experience how Grammarly can elevate your professional writing from start to finish. Visit Grammarly.com/podcast.  Sponsor: Continuing Education Company Use promo code Curb30 to get 30% off all online courses and webcast. Visit CMEmeeting.org/curbsiders to learn more. Sponsor: Freed Use code: CURB50 to get $50 off your first month when you subscribe!

In this podcast, experts in the field review current recommendations for cardiovascular risk assessment and the importance of early and sustained LDL-C lowering in high-risk patients.   To claim CE credit after listening to this episode, go to this link and check the "Already listened on another platform?" box: 

I am honored to have Dr. Tom Dayspring join me again today for another AMA session. He and I have done eight podcasts before, and this is a continuation of our last Ask Me Anything episode.  Dr Dayspring is an esteemed expert on internal medicine and clinical lipidology. He is likely one of the most influential worldwide lipid experts, so I am thrilled to have him back with me to dive into various topics related to listener questions, including the impact of hormone replacement therapy on lipid changes, methods of administration, and why bioidentical hormone replacement therapy is preferable for managing both menopausal symptoms and lipid health. We discuss medications, including PCSK9 inhibitors and GLP-1s, as well as intermittent fasting, lipids, and cardiovascular disease risk. We also examine how heart disease develops gradually, over time, the impact of stress and lifestyle, and Dr. Dayspring shares the labs he recommends beyond traditional lipids, ApoB, and LpA. In our discussion, Dr. Dayspring noted that he was not in a position to speak about GLP-1 therapies or microdosing. Since I received many questions from listeners on those topics, I will host a future solo AMA to address some of their concerns. Today's conversation with Dr. Tom Dayspring is truly invaluable, and I trust you will walk away with valuable insights you can share with your healthcare providers. We created a PDF - cynthiathurlow.com/lipids -  specifically for listeners that outlines key labs to discuss with your providers and questions to ask them to help you advocate for your own health and your family members' health. IN THIS EPISODE, YOU WILL LEARN: Why being physically fit does not always eliminate the risk of heart problems arising How ApoB and cholesterol contribute to heart disease over decades Why the early testing of risk factors is essential How chronic stress increases the risk of heart disease  How high cortisol affects insulin sensitivity and glucose regulation How stress impacts endothelial and nitric oxide function The link between low Omega-3 levels and heart problems How insulin resistance degrades heart health How high homocysteine levels can impair endothelial function and contribute to cardiovascular problems Connect with Cynthia Thurlow   Follow on⁠ X⁠,⁠ Instagram⁠ &⁠ LinkedIn⁠ Check out Cynthia's⁠ website⁠ Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community ⁠(The Midlife Pause/Cynthia Thurlow⁠)⁠ ⁠ Cynthia's⁠ Menopause Gut Book⁠ is on presale now! Cynthia's⁠ Intermittent Fasting Transformation⁠ Book ⁠The Midlife Pause supplement line⁠ Connect with Dr. Thomas Dayspring On X (@DrLipid) On LinkedIn

Join Kate, Gary and Mark (Henry has the day off) as we discuss 3 useful new studies: colorectal cancer screening reminders, aspirin or clopidogrel for secondary prevention of CV events, and lipid lowering drugs and dementia risk

Yogev Debbi and Prof Avi Schroeder (Technion Israel Institute of Technology), co-founded Mana bio along with Dr. Kira Radinsky and Roy Nevo. They are leveraging data, machine learning and high throughput screening to design novel Lipid NanoParticles for targeted extrahepatic delivery of nucleic acid therapeutics and vaccines. Lipid nanoparticles are microscopic fatty bubbles that deliver genetic medicines into your cells—think of them as the FedEx trucks of molecular biology. Remember the mRNA vaccines that saved millions during COVID? They used lipid nano particles as the delivery vehicle.. The little secret behind those vaccines is that we got lucky. Those lipid nanoparticles worked beautifully for the liver and immune system. But if you try to deliver RNA to your brain, your lungs, or a tumor, those would be a massive failure! Scientists are still running thousands of experiments hoping to stumble onto the right formulation. This actually was my postdoc work as well, which makes this episode very special. I always wished there was a better way to design these delivery vehicles—and that's exactly what today's guests have built with AI." We talk about how they founded and currently building Mana Bio- a big part around how biologists and chemists can interact with technologists, especially data and AI geeks to build something important. Their story provides a great framework for scientists and tech folks to work together. Shownotes: https://www.mana.bio/ How Avi got started using data/AI to design LNPs Optimizing LNP formulations targeting different organs Working with Bob Langer and Dan Anderson @MIT Yogev transitioning to gene editing Defining the problem & cross disciplinary conversations and projects Language that helps interactions between scientists and software/AI folks Deepdive into the platform- building data sets Data scraping, validation, improvisation, new data generation (both positive and negative data) Cleaning data and normalization Work in the wet lab: 'I trust my colleagues and believe data can be replicated" Data moats: Proprietary data vs public data Daily routine in the lab and interactions with the data/AI team Cross Functional dynamics Scientists trying to save money vs optimizing for more valuable time Lab hypothesis predictions vs AI predictions: competitive spirit Factoring in errors by the machines and humans Business model: Building customized solutions for drug delivery Potentially becoming a pharma company Regulatory affairs Fears that keep them up Dynamics of a diverse founding team: Roy Nevo and Dr. Kira Radinsky (the other two co founders) Message to academia: "Publish more data- including failures. This will accelerate science" Omri Drory, Kira Radinsky https://www.youtube.com/watch?v=y5hX3vq3iNk

In this episode of The Poultry Nutrition Blackbelt Podcast, Dr. Dawn Koltes from Iowa State University shares her research on enzymes in turkey nutrition. She explains the differences between endogenous and exogenous enzymes, how turkey feeding practices have evolved, and why more updated research is needed. Listen now on all major platforms!"Exogenous enzymes are essentially enzymes that we are providing to the bird, while the endogenous ones are produced by the bird."Meet the guest: Dr. Dawn Koltes earned her M.S. and Ph.D. in Genetics from Iowa State University, where she focused on animal breeding and genetics. She has served as a postdoctoral researcher, research scientist, and faculty member, currently holding the position of Assistant Professor at Iowa State University. Her research focuses on poultry nutrition, particularly enzyme utilization and lipid metabolism in turkeys. Liked this one? Don't stop now — Here's what we think you'll love!Dr. Sara Llamas-Moya: Enzyme Innovations in Poultry | Ep. 102Dr. Lisa Bielke: Feed Additives for Poultry Gut Health | Ep. 105What you'll learn:(00:00) Highlight(01:39) Introduction(02:44) Endogenous x exogenous enzymes(04:55) Turkey diet phases(05:35) Limited research(06:34) Exogenous enzymes(08:22) Lipid trials(10:11) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like:Kerry* Fortiva- Barentz- Kemin- Poultry Science Association- BASF- Anitox

Longevity, Success, Healthy Living, and Nutrition Made Simple Join Our Health Club Community FREE https://www.drasa.com/health-club   Visit Us At Our Health Club Retreats https://www.drasa.com/retreats/ It's Dr. Asa Here... Ask Me Your Question! Text Me: 407-255-7076 Call Me: 888-283-7272 Send me a DM: @DrAsa We are here to help you live your best life. You don't have to live lower than your potential for the rest of your life! Also our Health Club Providers are here to help guide and teach you on how quickly you can reach your health and wellness goals at: https://www.drasa.com/find-a-provider

Send us a textJosh Wageman is a returning guest on our show! Be sure to check out his first appearance on episode on 869 of BBR!Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease and, although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Josh is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!

(00:00) Intro and Matt's Background (04:28) Tips: Workspace, and. Going Big (07:25) Test Washing and Big Dumpers (12:18) Clear Tech and Oxygen (14:29) Gettiing Rosin into Carts (16:28) Blending for Higher Yield (19:56) Hashinene and Volatile Terps (21:39) Reclaiming Terps from Ice (24:54) Fats, Lipids, and Waxes Brand new guest Matt from Low Temp Plates joins us for an incredibly enlightening episode about the top tips and tricks for making world-class rosin at home. Matt talks about press loss, maximizing yield, and optimizing your work flow- but he also drops some incredible knowledge on reclaiming terpenes from freeze dryer ice, mixing bubble hashes to increase press yields, and more. Be sure to check out www.lowtemp-plates.com for more! Second part of this interview dropping soon, stay tuned. ----- Join GrowCast Membership TODAY! Connect with the most active, vibrant cannabis community in the entire world. Personal 24/7 garden support, Members Only content and discounts, and the Grand Pheno Hunt! www.growcast.com/membership  GrowCast Seed Co KLM DROP IS LIVE! Members get $20 off per pack- this Key Lime Madness Drop is going fast so don't miss it! www.growcast.com/seeds Code GROWCAST15 now works with grow KITS from AC Infinity! www.acinfinity.com use promo code GROWCAST15 for 15% off the BEST grow fans in the game, plus tents, pots, scissors, LED lights, and now REFILLABLE FILTERS!

In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Lipid Lowering Drugs⁠ from the Cardiovascular section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

This is part 2 of OMS3 Trent Henderson's series to tackle Lipids!

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video, I break down ATX-304 (also known as OS-01 or OS-03) — a powerful small molecule AMPK activator being studied for fat loss, metabolic health, and longevity. If you've heard ATX-304 described as “exercise in a capsule,” you'll see why after going through the research, mechanisms, human trials, and potential applications.I also share how ATX-304 works differently than GLP-1s, why it preserves muscle while supporting fat loss, and what the future may hold for this compound in anti-aging medicine.

Cardiovascular expert Colleen Walsh-Irwin returns to NP Pulse for an in-depth look at hyperlipidemia and the importance of controlling LDL-C levels. Walsh-Irwin also walks us through lipid panels, risk scoring and the many tools NPs have at their disposal to keep patients healthy and informed.  This podcast is made possible by Amgen.

In this episode of The Poultry Nutrition Blackbelt Podcast, Savannah Wells from the University of Arkansas explores the use of soybean add-backs and soybean genotype selection for improving nutrient composition in poultry diets. She explains their energy value, moisture content, and practical inclusion in broiler feed. Listen now on all major platforms!"With more soybean crushing, we're producing more add backs, and the idea is to re-incorporate them into soybean meal to boost its energy content."Meet the guest: Savannah Wells is a Graduate Student Research Assistant at the University of Arkansas, where she is pursuing her PhD in Poultry Science. She holds a B.S. and M.S. in Poultry Science from the same institution, along with a B.A.Sc. in Animal Science from Arkansas State University.  With a unique background in crop and animal science, she brings valuable insight into feed formulation strategies. Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:31) Introduction(04:25) Soybean add backs(06:46) Lipid composition(07:46) Broiler diet strategy(10:07) Energy value comparison(11:05) Secondary ingredient effects(12:35) Closing research summaryThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like:* Kemin* Kerry- Anitox- BASF- Poultry Science Association

On today's show: The lineup for Coachella 2026 has already been announced. Good Vibes at 6:55! Alyssa likes to hug, Bill does not, and that has caused some problems. The Group Chat: Olivia recently got engaged but isn't sure how to pull off the wedding of her dreams. Alyssa's College of Knowledge! Alyssa is trying to help find a lost cat in Old Brooklyn. Plus, do you need to fast before getting a blood test?

Dr. Vera Tarman sits down with Dr. Bart Kay—former professor of health sciences turned “nutrition science watchdog”—to unpack a big, practical question for people in recovery from ultra-processed food use: If sugar needs to go, what about other carbs? And where does dietary fat fit in? We explore Dr. Kay's perspective on the Randle (Randall) cycle, insulin resistance, mixed macro diets, seed oils, ketogenic/carnivore patterns, and real-world considerations for folks with sugar/UPF addiction who struggle to “moderate.” We also discuss staged change (don't flip your diet overnight), what “abstainer vs. moderator” can mean in food recovery, and how to keep any nutrition experiment aligned with your health team and your recovery plan. What we cover The “Randle cycle,” plain-English: why mixing higher carbs and higher fats may worsen metabolic friction, and why choosing one dominant fuel is central to Dr. Kay's model. Insulin resistance re-framed: why Dr. Kay views it as a protective cellular response (his position) and how that informs low-carb/carnivore advocacy. Carbs in recovery: “quit sugar” vs. “how low is low?”—Dr. Kay's thresholds (e.g., ≤50 g/day unlikely to cause problems in his view) and why many with UPF addiction do better with abstinence than moderation. Fats & satiety: why dietary fat often increases fullness cues; practical guardrails; “can you eat too much fat or protein?” Seed oils: Dr. Kay's strong critique of industrial seed oils and his inflammation concerns. Cholesterol worries on low-carb/carnivore: why lipid numbers may rise and how Dr. Kay interprets A1C and lipid changes (controversial; see note below). GLP-1s, metformin & meds: Dr. Kay's take on drug mechanisms vs. root-cause nutrition changes. Change management: why he recommends a 4–6 week ramp instead of an overnight switch to very low-carb/carnivore; supporting thyroid, energy, and the microbiome while you transition. Recovery lens: abstainer vs. moderator, harm-reduction steps when “only food will regulate,” and building a plan that supports mental health and addiction recovery. Key takeaways Abstinence can be a kindness. If you're a “can't moderate sugar” person, treating sugar/UPFs as an abstinence-worthy trigger can protect your recovery. Don't crash-diet your microbiome. If you're experimenting with lower-carb or carnivore, step down over 4–6 weeks with plenty of electrolytes, hydration, and support. Pick a lane with macros. In Dr. Kay's model, mixing higher carbs with higher fats is the most metabolically problematic; choosing one dominant fuel source may reduce friction. Numbers are data, not destiny. Lipids and A1C can shift on low-carb—interpret changes with a clinician who understands your whole picture (medical history, meds, symptoms, goals). Harm-reduction still counts. If full abstinence isn't feasible today: remove red-light foods first, shrink access, use “pause + plan” tools, and reach out before the binge. About our guest Dr. Bart Kay is a former professor of human physiology, nutrition, and vascular pathophysiology with teaching/research stints in New Zealand, Australia, the UK, and the US. He's consulted for elite sport and defense organizations and now educates the public on YouTube as a self-described nutrition myth-buster. One of his core topics is the Randle cycle and its implications for diet composition. Dr. Kay's YouTube: https://www.youtube.com/@Professor-Bart-Kay-Nutrition   The content of our show is educational only. It does not supplement or supersede your healthcare provider's professional relationship and direction. Always seek the advice of your physician or other qualified mental health providers with any questions you may have regarding a medical condition, substance use disorder, or mental health concern.

Join Dr. Mohamed Abou-el-Enein, Editor-in-Chief of Molecular Therapy Methods & Clinical Development, as he discusses a recent article published in MTMCD with co-authors Drs. Daniel Stone, Harrison Dulin, and Keith R. Jerome from the Fred Hutchinson Cancer Center. The article, “Serum factors create species-specific barriers to hepatic gene transfer by lipid nanoparticles in liver-humanized mice,” will appear in MTMCD’s upcoming special issue, Lipid nanoparticles for cell and gene therapy. If you enjoy this episode, check out our hybrid event this fall that will allow you to engage with pioneering researchers in gene editing! Breakthroughs in Targeted In Vivo Gene Editing will be held in San Diego and virtually November 20-21. Register to secure your spot or submit an abstract through Sept. 12 for the opportunity to present your research! Music: 'Electric Dreams' by Scott Buckley - released under CC-BY 4.0. www.scottbuckley.com.auShow your support for ASGCT!: https://asgct.org/membership/donateSee omnystudio.com/listener for privacy information.

This is a fascinating podcast episode from Dr. Lipid himself on desmosterol.  What is it?  How do we measure it?  Why should we care? Pharmacists are well-positioned to guide patients in understanding the role of desmosterol, how medications may influence its levels, the options for measuring it, and the steps to take if levels are too high or too low. Dr. Thomas Dayspring: linkedin.com/in/thomas-dayspring-md-facp-fnla-3aaa876 or @DrLipid on X  Tamara Ruggles, PharmD: linkedin.com/in/tamara-ruggles-491882251 Resource on lipids recommended by Dr. Dayspring: https://familyheart.org/ Wages PA, Kim HH, Korade Z, Porter NA. Identification and characterization of prescription drugs that change levels of 7-dehydrocholesterol and desmosterol. J Lipid Res. 2018 Oct;59(10):1916-1926. doi: 10.1194/jlr.M086991. Epub 2018 Aug 7. PMID: 30087204; PMCID: PMC6168312.  Available at:  https://pubmed.ncbi.nlm.nih.gov/30087204/  The Geriatric Pharmacy Focus podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

Send us a textDr. Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease, and although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Dr. Josh Wageman is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!

Dr. Gillett and James O'Hara discuss a new paper they have published.Studies/References:► https://www.sciencedirect.com/science/article/pii/S266666772500145X► https://pmc.ncbi.nlm.nih.gov/articles/PMC11170451/For High-quality labs:► http://sagebio.com/For information on the Gillett Health clinic, lab panels, and health coaching:► https://GillettHealth.comFollow Gillett Health for more content from James and Kyle► https://instagram.com/gilletthealth► https://www.tiktok.com/@gilletthealth► https://twitter.com/gilletthealth► https://www.facebook.com/gilletthealthFollow Kyle Gillett, MD► https://instagram.com/kylegillettmdFollow James O'Hara, NP► https://Instagram.com/jamesoharanpFor 10% off Gorilla Mind products, including SIGMA: Use code “GH10”► https://gorillamind.com/For discounts on high-quality supplements►https://www.thorne.com/u/GillettHealth#cholesterol #lipids #health #podcastAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Lipids are an incredibly dense subject that you've probably spent MANY hours to understand only to lose the big picture. OMS3 Trent Henderson aims to attack this problem in this high yield 2-episode series!

Send us a textCellular clean up by immune cells and how early-life fructose exposure leads to neurodevelopmental problems.Episode Summary: Dr. Justin Perry talks about the body's constant cellular turnover—about 3 million cells die per second in adults (double in children and women)—handled by phagocytes like macrophages that engulf and digest debris to prevent diseases like lupus. They explore phagocytosis steps, macrophage adaptations in tissues like the brain (microglia), and how high fructose intake impairs microglial function in developing mice, leading to uncleared brain cells and anxiety-like behaviors, with implications for human neurodevelopmental disorders amid rising fructose consumption.About the guest: Justin Perry, PhD is an immunologist and clinical psychologist who leads a lab at Memorial Sloan Kettering Cancer Center focusing on how the body clears dead cells and debris to maintain homeostasis.Discussion Points:The body turns over 1-2% of its 30 trillion cells daily, mostly blood cells, but neurons in kids and endometrium in women turnover at ~2x this ratePhagocytosis involves "find me," "eat me," and digestion signals; failures can cause autoimmunity.Microglia are brain macrophages that uptake fructose via GLUT5 transporter.Early high fructose exposure (comparable to one soda daily) impairs the pruning of synapses and dead neurons.In mice, prenatal or postnatal fructose causes phagocytosis deficits in the prefrontal cortex, leading to heightened fear responses and poor fear extinction, mimicking anxiety disorders.Fructose correlates with rising neurodevelopmental issues like autism and anxiety; it's passed via breast milk, and liquid forms (e.g., sodas) overwhelm metabolic shields more than solid fruits.Macrophages may hold keys to diseases from atherosclerosis to cancer; deleting GLUT5 in microglia reverses fructose's effects, hinting at evolutionary roles in aging or low-oxygen states.Related content:M&M 215: Cancer Metabolism: Sugar, Fructose, Lipids & Fasting | Gary PattiArticle | Dietary Fructose & Metabolic Health: An Evolutionary PerspectiveReference Paper:Study | Early life high fructose impairs microglial phagocytosis and neurodevelopment*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Did you know that brain fog can be a metabolic warning sign? In this episode, Dr. Austin Perlmutter breaks down how blood sugar swings, inflammation, and poor metabolic health silently chip away at your brain function over time. We also talk about how to eat to protect your mood, cognition, and long-term brain health, including the latest research on how to prevent dementia and Alzheimer's disease.Timestamps:[1:38] Intro[3:43] Conversation with Dr. Austin Perlmutter[10:27] You mentioned that inflammation can manifest in different ways, is there a reason it manifests a different way for one person than another?[17:53] What is excites you the most as far as the shifts we can make that result in better cognitive function?[29:34] Do you agree with Alzheimer's being called “type 3 diabetes”?[38:07] Are you recommending that people wear a CGM or that they get their metabolic markers tested regularly, and if so, what are those markers we should be looking at?[50:13] How can we improve brain fog after 40?[59:23] Do you think our screens and social media habits are changing  our brain function, and is there anything we can be doing nutritionally especially if we have to be on our computers all day for work?Episode Links:Dr. Austin Perlmutter's Website Follow Dr. Austin on InstagramBrain Wash: Detox Your Mind for Clearer Thinking, Deeper Relationships, and Lasting Happiness Big Bold HealthDr. Austin's YouTubeTop Causes of Brain FogBiomarkers:Hemoglobin A1cBasic metabolic panel (fasting insulin, fasting glucose)Lipid panel - Triglycerides are the key markerWaist to hip ratioSMASH fishSponsors:Go to https://thisisneeded.com/  and use coupon code WELLFED for 20% off your first order.Go to boncharge.com/WELLFED and use coupon code WELLFED to save 15% off any order.Go to http://mdlogichealth.com/whey-protein, and use coupon code WELLFED for 10% off.Go to wellminerals.us/creatine and use code WELLFED to get 10% off your order.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Suzanne: Thank you for your time in advance. In late 2021, my husband was diagnosed with Stage IV prostate cancer. He underwent six rounds of chemo along with Eligard injections. After his last scans, whole body and bone, we were told the cancer is "stabilized". He is currently on 300 mg of Nubeqa 2x a day (down from 4 x because I asked about it) and Lupron injections every 3 months. We have consciously changed our diet (no added sugar, no alcohol, no processed foods) and he is doing pretty well, although, he does fatigue and sweat easily. My question is whether you believe that taking a couple of your home tests would be beneficial for him? I worry about these powerful drugs he is being given and have noticed a reluctance from the doctor about reducing his drugs any further. Thank you again!                                                Sheena: Hi Dr C! Hope you and your team are well. I recently went for blood work. I fasted for 14 hours and was wondering what your thoughts are specifically regarding my Lipid Panel and Iron Panel. My triglycerides is 1.83, Total 4.05, HDL 1.72 and LDL 1.63 (all mmol/L). For iron my levels are 37 umol/L, iron binding 0.70 umol/L, and ferritin 44 ugL. My Dr says she's concerned with my triglycerides. How can I lower it? And shes concerned with my ferritin and iron levels so shes sending me for a Hemochromatosis blood test to see why the levels are off. (My fasting glucose is 4.9, hbA1c is 5.2, TSH is 1.04 and Auto CBC is 3.8). Would love your thoughts and any food and supplementation recommendations would be appreciated! Love you and all the best to everyone on their health journey!                                                            Madhia: Hello My Dr is giving me a hard time to prescribe MRI for my breast exam. Do you have any Dr you can recommend that would help me in greater Los Angeles area?                                                                                                 Margie: My son, who is 46 years old has had Alpha-Gal for approximately 10 years. Now his wife has also been diagnosed with it. I am aware it is caused by a tick bite. He constantly has mass cell inflammation including breathing and allergy issues. Could you please explain specifically how this disease affects the body's immune system and which of your protocols should be used to bring the body back into balance. Will that particular protocol bring the body back into balance enough so that it will relieve the mass cell inflammation and they can return to eating mammal meat?                                                     Jackie: Hi Dr. Cabral thank you for all that you do. You have made a tremendous impact in my and my clients lives. My husband has just finally been diagnosed after 10 years of misdiagnosis with neurogenic TOS. We have a great rehab team working on the biomechanics and we are exploring Big 5 root causes. I was wondering what natural pain management methods you would recommend during the process pain is 10/10 and conventional medicines wants to basically kill the nerve or put him on Lyrica which neither are an option for us. We are exploring accupuncture, grounding and adrenal sooth/inflammasoothe/cbd protocol. Any other alternative inflammation reduction techniques or devices you would recommend? Could you do a podcast on natural pain management strategies for people with chronic pain?          Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3495 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

I am deeply honored to reconnect with Dr. Thomas Dayspring, who joined me in 2024 for an immensely popular five-part series. Dr. Dayspring is certified in internal medicine and clinical lipidology. He is a distinguished fellow of both the American College of Physicians and the National Lipid Association.  Today, we have the first episode in a new series of conversations with Dr. Dayspring, in which he will share more of his perspective and answer more questions from listeners. In our discussion, we review the basics about cholesterol, triglycerides, and lipoproteins, exploring the factors that contribute to the development of cardiovascular disease, the significance of ApoB and Lp(a), and the risk factors for younger women. We also dive into the limitations of traditional allopathic medicines, and Dr. Dayspring shares his views on lipids, lipid changes in menopause, specific ways to address ApoB, some of the challenges associated with statin therapy, and more.  Dr. Dayspring brings a wealth of experience and expertise to this discussion, and you are sure to find this series as invaluable as the last. IN THIS EPISODE, YOU WILL LEARN: Dr. Dayspring revisits the differences between cholesterol, triglycerides, and lipoproteins What atherosclerosis is, and why it is concerning Dr. Dayspring explains the structure and function of lipoproteins The role of ApoB in lipoprotein particles and its significance in atherosclerosis Some of the risk factors for lipid abnormalities in younger women Lipid changes that occur as women transition from perimenopause to menopause  Dr. Dayspring shares his take on statin therapy Ways to address high ApoB Dr. Dayspring's suggested goals for ApoB therapy Connect with Cynthia Thurlow   Follow on ⁠X⁠, ⁠Instagram⁠ & ⁠LinkedIn⁠ Check out Cynthia's ⁠website⁠ Submit your questions to ⁠support@cynthiathurlow.com⁠ Connect with Dr. Thomas Dayspring On⁠ X⁠ (@Drlipid) On⁠ LinkedIn⁠ ⁠Journal Article: Atherosclerosis: Non-genetic influences on lipoprotein(a) concentrations⁠  ⁠Journal of the American Heart Association: Trajectories of Blood Lipid Profiles in Midlife Women: Does Menopause Matter?⁠  

In this episode, I sit down with Dr. Rupy Aujla, an NHS GP and the founder of The Doctor's Kitchen, an app that includes doctor-approved recipes to cook at home. In this conversation, we dive into why cardiovascular disease remains the #1 killer worldwide, the connection between cholesterol and heart health, how fiber acts as a “magical nutrient” for the body, how to introduce it into your daily meals, and the role of lifestyle choices in preventing illness and supporting long-term brain and heart health. *** About Dr. Rupy Aujla: After suffering a significant heart condition, he dove deep into the science of nutritional medicine and was able to reverse his condition through food and lifestyle. In 2015, he launched The Doctor's Kitchen as a way to teach people how to cook their way to better health and to showcase the medicinal effects of eating well. The incredible “Doctor's Kitchen” cooking app has over 1000 delicious, science-backed recipes and 20 brand new ones added each month. There's also a handy meal planner that will personalise recipes based on your preferences. It actually suggested a delicious looking salmon poached in harissa coconut sauce, and  olive and date braised chicken, which suit my personal dietary needs and all sound great. You can download and use the app completely for free using this link. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: David's Protein: Buy four cartons and get your fifth one completely free | Head to https://davidprotein.com/pages/neuro Ketone IQ: Go to https://ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. FIGS: You can get 15% off your first order at https://wearfigs.com with the code FIGSRX. Caraway: https://caraway.com/neuro for an additional 10% off your purchase MUDWTR: The coffee alternative. If you're ready to ditch the crash and sip smarter, go to https://mudwtr.com and use code NEURO to get 43% off + free shipping. *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics: 00:02:43: Lipid panels & overlooked markers 00:05:21: Atherosclerosis explained 00:08:13: Misleading “normal” cholesterol panels 00:10:48: Why heart disease remains #1 killer & prevention timeline 00:12:51: Cholesterol & Alzheimer's; LDL targets for brain health 00:15:12: Cholesterol causality, very low LDL safety 00:19:23: Statins & pharmacological interventions 00:26:02: Ultra-processed foods & saturated fats 00:29:26: Fiber's role in lowering LDL 00:32:05: How fiber binds bile acids & removes cholesterol 00:33:29: Gut microbiome & short-chain fatty acids from fiber 00:35:05: Lowering ApoB, LDL by eating plant-rich foods, portfolio diet 00:37:15: Oats & heart health 00:41:51: Pesticides in fruits and vegetables 00:45:37: Eggs and cholesterol 00:48:18: Soy 00:53:55: Balanced eating 00:57:40: Stress, sleep & cardiovascular disease 00:59:55: Memorable patient stories, family member with stent 01:04:04: How to reduce risk of heart attack or stroke with diet Learn more about your ad choices. Visit megaphone.fm/adchoices